Standard name Systematic name Name description Description
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex Subunit of NuA4, an essential histone acetyltransferase complex; positions Piccolo NuA4 for efficient acetylation of histone H4 or histone H2A; relocalizes to the cytosol in response to hypoxia; similar to human tumor suppressor ING1 and its isoforms ING4 and ING5
Visualize the interactome of YNG2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.117 0.080 NaN
Nucleus 0.934 0.866 0.932
Mito NaN 0.507 NaN
SpindlePole NaN NaN 0.057

GFP localization & abundance

GFP localization GFP abundance
nucleus low signal

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
YNG2 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex physical 15 5 12 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 8 3 8 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 7 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin physical 6 2 6 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
HHT1 YBR010W Histone H3 physical 6 4 4 Affinity Capture-Western, Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Reconstituted Complex, Protein-peptide
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 6 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex physical 5 2 5 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes physical 5 2 5 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex physical 5 2 4 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex physical 5 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 5 3 3 Synthetic Rescue, Synthetic Rescue, Dosage Lethality, Dosage Lethality, Phenotypic Suppression
HHT2 YNL031C Histone H3 physical 5 3 3 Affinity Capture-Western, Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Reconstituted Complex
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 5 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 5 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 5 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 5 1 2 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
BRE1 YDL074C E3 ubiquitin ligase genetic 4 3 3 Synthetic Lethality, Synthetic Rescue, Synthetic Rescue, Positive Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 4 3 3 Synthetic Lethality, Synthetic Rescue, Synthetic Rescue, Positive Genetic
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 4 3 3 Synthetic Lethality, Synthetic Rescue, Synthetic Rescue, Positive Genetic
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes physical 4 3 3 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 4 3 3 Synthetic Lethality, Synthetic Lethality, Dosage Growth Defect, Negative Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 4 3 3 Synthetic Lethality, Synthetic Rescue, Synthetic Rescue, Positive Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 4 3 2 Negative Genetic, Positive Genetic, Synthetic Lethality, Synthetic Lethality
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
ADA2 YDR448W Transcription coactivator genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 3 3 3 Synthetic Lethality, Negative Genetic, Positive Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
IKI3 YLR384C Subunit of Elongator complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Positive Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 3 2 2 Synthetic Rescue, Synthetic Rescue, Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
HTA1 YDR225W Histone H2A genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 3 2 2 Synthetic Rescue, Synthetic Rescue, Positive Genetic
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 3 2 2 Positive Genetic, Synthetic Lethality, Synthetic Lethality
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 3 2 2 Synthetic Rescue, Synthetic Rescue, Positive Genetic
GET1 YGL020C Subunit of the GET complex genetic 3 2 2 Negative Genetic, Synthetic Lethality, Synthetic Lethality
DIA2 YOR080W Origin-binding F-box protein genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
GDS1 YOR355W Protein involved in histone H4 acetylation at ribosomal protein genes genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
SAS4 YDR181C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 3 2 2 Negative Genetic, Synthetic Lethality, Synthetic Lethality
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 3 2 2 Synthetic Lethality, Synthetic Rescue, Synthetic Rescue
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
PEX4 YGR133W Peroxisomal ubiquitin conjugating enzyme genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Positive Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
CDC73 YLR418C Component of the Paf1p complex genetic 2 2 2 Synthetic Lethality, Positive Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 2 2 2 Synthetic Lethality, Positive Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 2 2 2 Synthetic Lethality, Positive Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 2 2 2 Synthetic Lethality, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 2 2 2 Negative Genetic, Positive Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 2 2 2 Synthetic Lethality, Positive Genetic
SPP1 YPL138C Subunit of COMPASS (Set1C) genetic 2 2 2 Synthetic Lethality, Positive Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 2 2 2 Negative Genetic, Positive Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
RTT109 YLL002W Histone acetyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 2 2 1 Synthetic Growth Defect, Phenotypic Suppression
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope genetic 2 2 1 Negative Genetic, Positive Genetic
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
UBC13 YDR092W E2 ubiquitin-conjugating enzyme genetic 2 2 1 Phenotypic Suppression, Synthetic Growth Defect
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
FUN12 YAL035W Translation initiation factor eIF5B genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
MDM20 YOL076W Non-catalytic subunit of the NatB N-terminal acetyltransferase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LSM1 YJL124C Lsm (Like Sm) protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
APC2 YLR127C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
ASF1 YJL115W Nucleosome assembly factor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BDF1 YLR399C BET family transcriptional regulator genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
INO80 YGL150C Nucleosome spacing factor genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
PEP3 YLR148W Component of CORVET membrane tethering complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
REF2 YDR195W RNA-binding protein genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SPO7 YAL009W Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SRO9 YCL037C Cytoplasmic RNA-binding protein genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VMA4 YOR332W Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VMA6 YLR447C Subunit d of the V0 integral membrane domain of V-ATPase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VMA7 YGR020C Subunit F of the V1 peripheral membrane domain of V-ATPase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PEP5 YMR231W Histone E3 ligase, component of CORVET membrane tethering complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS33 YLR396C ATP-binding protein that is a subunit of the HOPS and CORVET complexes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS45 YGL095C Protein of the Sec1p/Munc-18 family genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
PEX6 YNL329C AAA-peroxin genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
KSP1 YHR082C Serine/threonine protein kinase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
HHT1 YBR010W Histone H3 genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VAN1 YML115C Component of the mannan polymerase I genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS21 YOR089C Endosomal Rab family GTPase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DEF1 YKL054C RNAPII degradation factor genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SIR3 YLR442C Silencing protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SNF8 YPL002C Component of the ESCRT-II complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GRX5 YPL059W Glutathione-dependent oxidoreductase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
NBA1 YOL070C Protein involved in axial bud site selection genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VMA22 YHR060W Protein that is required for vacuolar H+-ATPase (V-ATPase) function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PEX14 YGL153W Central component of the peroxisomal importomer complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CDC26 YFR036W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
PEX10 YDR265W Peroxisomal membrane E3 ubiquitin ligase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PEX13 YLR191W Peroxisomal importomer complex component genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SWC5 YBR231C Component of the SWR1 complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SWI6 YLR182W Transcription cofactor genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
STP22 YCL008C Component of the ESCRT-I complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
STE50 YCL032W Adaptor protein for various signaling pathways genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ESC2 YDR363W Sumo-like domain protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ATP1 YBL099W Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SWC3 YAL011W Protein of unknown function genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TIF3 YPR163C Translation initiation factor eIF-4B genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SYS1 YJL004C Integral membrane protein of the Golgi genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TPM1 YNL079C Major isoform of tropomyosin genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
OCH1 YGL038C Mannosyltransferase of the cis-Golgi apparatus genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SAS5 YOR213C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PEX32 YBR168W Peroxisomal integral membrane protein genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LDB7 YBL006C Component of the RSC chromatin remodeling complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RNH70 YGR276C 3'-5' exoribonuclease genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RUD3 YOR216C Golgi matrix protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HUR1 YGL168W Protein with a role in DNA repair genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SGO1 YOR073W Component of the spindle checkpoint genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
PEX3 YDR329C Peroxisomal membrane protein (PMP) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
THR1 YHR025W Homoserine kinase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RSA1 YPL193W Protein involved in the assembly of 60S ribosomal subunits genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HXT4 YHR092C High-affinity glucose transporter genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
PEX8 YGR077C Intraperoxisomal organizer of the peroxisomal import machinery genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MSC1 YML128C Protein of unknown function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS36 YLR417W Component of the ESCRT-II complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Positive Genetic
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p genetic 1 1 1 Dosage Growth Defect
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 1 1 1 Dosage Lethality
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Positive Genetic
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex genetic 1 1 1 Negative Genetic
PUS7 YOR243C Pseudouridine synthase genetic 1 1 1 Negative Genetic
PRP3 YDR473C Splicing factor genetic 1 1 1 Negative Genetic
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Synthetic Lethality
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Positive Genetic
RSC3 YDR303C Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Dosage Lethality
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Dosage Growth Defect
KAP95 YLR347C Karyopherin beta physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Negative Genetic
TRM1 YDR120C tRNA methyltransferase genetic 1 1 1 Positive Genetic
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme genetic 1 1 1 Phenotypic Suppression
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 1 1 1 Negative Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 1 1 1 Positive Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 1 1 1 Synthetic Lethality
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 PCA
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Positive Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Dosage Lethality
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Dosage Growth Defect
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Positive Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Negative Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
HAT2 YEL056W Subunit of the Hat1p-Hat2p histone acetyltransferase complex genetic 1 1 1 Synthetic Lethality
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
AEP2 YMR282C Mitochondrial protein genetic 1 1 1 Negative Genetic
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing genetic 1 1 1 Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Positive Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
MAK10 YEL053C Non-catalytic subunit of the NatC N-terminal acetyltransferase genetic 1 1 1 Negative Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
MGS1 YNL218W Protein with DNA-dependent ATPase and ssDNA annealing activities genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Positive Genetic
MDS3 YGL197W Putative component of the TOR regulatory pathway genetic 1 1 1 Positive Genetic
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome genetic 1 1 1 Positive Genetic
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
RAD51 YER095W Strand exchange protein genetic 1 1 1 Synthetic Growth Defect
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Negative Genetic
ROX3 YBL093C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Dosage Growth Defect
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 1 1 1 Positive Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Positive Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Positive Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Positive Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Positive Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Positive Genetic
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex genetic 1 1 1 Positive Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Positive Genetic
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Positive Genetic
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Positive Genetic
SAW1 YAL027W 5'- and 3'-flap DNA binding protein genetic 1 1 1 Negative Genetic
SYF1 YDR416W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 1 1 1 Positive Genetic
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton genetic 1 1 1 Positive Genetic
AKL1 YBR059C Ser/Thr protein kinase genetic 1 1 1 Dosage Growth Defect
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 1 1 1 Synthetic Growth Defect
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 1 1 1 Negative Genetic
BUB2 YMR055C Mitotic exit network regulator genetic 1 1 1 Negative Genetic
HTB1 YDR224C Histone H2B physical 1 1 1 Reconstituted Complex
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Positive Genetic
BUD13 YGL174W Subunit of the RES complex genetic 1 1 1 Negative Genetic
ESL2 YKR096W hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Negative Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Negative Genetic
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Synthetic Growth Defect
AGX1 YFL030W Alanine:glyoxylate aminotransferase (AGT) genetic 1 1 1 Negative Genetic
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 1 1 1 Negative Genetic
RTN2 YDL204W Reticulon protein genetic 1 1 1 Negative Genetic
PCT1 YGR202C Cholinephosphate cytidylyltransferase genetic 1 1 1 Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Positive Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
DSS4 YPR017C Guanine nucleotide dissociation stimulator for Sec4p genetic 1 1 1 Negative Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 1 1 1 Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Negative Genetic
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Positive Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Dosage Growth Defect
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Negative Genetic
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Synthetic Lethality
MKK2 YPL140C MAPKK involved in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 1 1 1 Positive Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 1 1 1 Dosage Lethality
RAD59 YDL059C Protein involved DNA double-strand break repair genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Biochemical Activity
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Synthetic Lethality
AIR1 YIL079C Zinc knuckle protein genetic 1 1 1 Negative Genetic
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) genetic 1 1 1 Positive Genetic
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 1 1 1 Positive Genetic
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Negative Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Negative Genetic
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
APE3 YBR286W Vacuolar aminopeptidase Y genetic 1 1 1 Negative Genetic
MET16 YPR167C 3'-phosphoadenylsulfate reductase genetic 1 1 1 Negative Genetic
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 1 1 1 Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Negative Genetic
REX2 YLR059C 3'-5' RNA exonuclease genetic 1 1 1 Positive Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
ASI3 YNL008C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Positive Genetic
BIT2 YBR270C Subunit of TORC2 membrane-associated complex genetic 1 1 1 Positive Genetic
DDI1 YER143W Aspartic-type endopeptidase genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
CIN4 YMR138W GTP-binding protein involved in beta-tubulin (Tub2p) folding genetic 1 1 1 Synthetic Lethality
CIT2 YCR005C Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle genetic 1 1 1 Positive Genetic
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Positive Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
LPP1 YDR503C Lipid phosphate phosphatase genetic 1 1 1 Dosage Growth Defect
BIT61 YJL058C Subunit of TORC2 membrane-associated complex genetic 1 1 1 Positive Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 1 1 1 Reconstituted Complex
MSN5 YDR335W Karyopherin genetic 1 1 1 Negative Genetic
CSM3 YMR048W Replication fork associated factor genetic 1 1 1 Negative Genetic
PBY1 YBR094W Putative tubulin tyrosine ligase associated with P-bodies genetic 1 1 1 Negative Genetic
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation genetic 1 1 1 Positive Genetic
SAE2 YGL175C Endonuclease required for telomere elongation genetic 1 1 1 Positive Genetic
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Negative Genetic
SRL2 YLR082C Protein of unknown function genetic 1 1 1 Negative Genetic
THI6 YPL214C Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase genetic 1 1 1 Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Growth Defect
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
NUR1 YDL089W Protein involved in regulation of mitotic exit genetic 1 1 1 Negative Genetic
RMD5 YDR255C Component of GID Complex that confers ubiquitin ligase (U3) activity genetic 1 1 1 Negative Genetic
UGA4 YDL210W GABA (gamma-aminobutyrate) permease genetic 1 1 1 Dosage Growth Defect
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Positive Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Dosage Growth Defect
APC9 YLR102C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p genetic 1 1 1 Positive Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex physical 1 1 1 Biochemical Activity
PEX12 YMR026C C3HC4-type RING-finger peroxin and E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
PEX2 YJL210W RING-finger peroxin and E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Negative Genetic
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
NHP6A YPR052C High-mobility group (HMG) protein genetic 1 1 1 Positive Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Positive Genetic
TAF4 YMR005W TFIID subunit (48 kDa) genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Positive Genetic
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RPS1B YML063W Ribosomal protein of the small (40S) subunit genetic 1 1 1 Positive Genetic
PLC1 YPL268W Phospholipase C genetic 1 1 1 Synthetic Lethality
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Negative Genetic
ELO3 YLR372W Elongase genetic 1 1 1 Positive Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Negative Genetic
PEA2 YER149C Coiled-coil 12S polarisome subunit genetic 1 1 1 Negative Genetic
RAD17 YOR368W Checkpoint protein genetic 1 1 1 Positive Genetic
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 1 1 1 Phenotypic Suppression
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Synthetic Growth Defect
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex genetic 1 1 1 Synthetic Lethality
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
SNC1 YAL030W Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Dosage Growth Defect
SSQ1 YLR369W Mitochondrial hsp70-type molecular chaperone genetic 1 1 1 Positive Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Negative Genetic
FIG4 YNL325C Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase genetic 1 1 1 Positive Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
CST9 YLR394W SUMO E3 ligase genetic 1 1 1 Dosage Growth Defect
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Positive Genetic
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding genetic 1 1 1 Synthetic Lethality
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
SNX4 YJL036W Sorting nexin genetic 1 1 1 Negative Genetic
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes genetic 1 1 1 Negative Genetic
OST5 YGL226C-A Zeta subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
BUD8 YLR353W Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
EMC1 YCL045C Member of conserved endoplasmic reticulum membrane complex genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Positive Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Positive Genetic
EMC5 YIL027C Member of conserved ER transmembrane complex genetic 1 1 1 Positive Genetic
ARG82 YDR173C Inositol polyphosphate multikinase (IPMK) genetic 1 1 1 Positive Genetic
CHS3 YBR023C Chitin synthase III genetic 1 1 1 Negative Genetic
JEM1 YJL073W DnaJ-like chaperone required for nuclear membrane fusion during mating genetic 1 1 1 Positive Genetic
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 1 1 1 Negative Genetic
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p genetic 1 1 1 Negative Genetic
SPA2 YLL021W Component of the polarisome genetic 1 1 1 Negative Genetic
AZF1 YOR113W Zinc-finger transcription factor genetic 1 1 1 Positive Genetic
REV3 YPL167C Catalytic subunit of DNA polymerase zeta genetic 1 1 1 Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Positive Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
RDI1 YDL135C Rho GDP dissociation inhibitor genetic 1 1 1 Positive Genetic
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Negative Genetic
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 1 1 1 Affinity Capture-MS
ENV11 YGR071C Protein proposed to be involved in vacuolar functions genetic 1 1 1 Positive Genetic
ENT5 YDR153C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Positive Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Synthetic Lethality
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Negative Genetic
INP51 YIL002C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Negative Genetic
RPL19B YBL027W Ribosomal 60S subunit protein L19B genetic 1 1 1 Positive Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Dosage Growth Defect
KIP2 YPL155C Kinesin-related motor protein involved in mitotic spindle positioning genetic 1 1 1 Positive Genetic
FRK1 YPL141C Protein kinase of unknown cellular role genetic 1 1 1 Positive Genetic
HLR1 YDR528W Protein involved in regulation of cell wall composition and integrity genetic 1 1 1 Negative Genetic
GEF1 YJR040W Voltage-gated chloride channel genetic 1 1 1 Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Negative Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Negative Genetic
RMI1 YPL024W Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex genetic 1 1 1 Negative Genetic
AGP2 YBR132C Plasma membrane regulator of polyamine and carnitine transport genetic 1 1 1 Positive Genetic
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Negative Genetic
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 1 1 1 Positive Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
PEX1 YKL197C AAA-peroxin genetic 1 1 1 Positive Genetic
CUE1 YMR264W Ubiquitin-binding protein genetic 1 1 1 Positive Genetic
HXK1 YFR053C Hexokinase isoenzyme 1 genetic 1 1 1 Positive Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
PUF4 YGL014W Member of the PUF protein family genetic 1 1 1 Positive Genetic
STP1 YDR463W Transcription factor genetic 1 1 1 Positive Genetic
URA1 YKL216W Dihydroorotate dehydrogenase genetic 1 1 1 Positive Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Positive Genetic
IPF1 YDL176W Protein of unknown function involved in actin patch formation genetic 1 1 1 Positive Genetic
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Positive Genetic
IRC3 YDR332W Double-stranded DNA-dependent helicase of the DExH/D-box family genetic 1 1 1 Positive Genetic
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
YNL058C YNL058C Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
YPT11 YNL304W Rab GTPase genetic 1 1 1 Negative Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Dosage Growth Defect
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 1 1 1 Positive Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Negative Genetic
BYE1 YKL005C Negative regulator of transcription elongation genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Positive Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Negative Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Negative Genetic
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 1 1 1 Negative Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 1 1 1 Positive Genetic
FRD1 YEL047C Soluble fumarate reductase genetic 1 1 1 Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
GIP4 YAL031C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p genetic 1 1 1 Positive Genetic
MUB1 YMR100W MYND domain-containing protein genetic 1 1 1 Negative Genetic
GEP5 YLR091W Protein of unknown function genetic 1 1 1 Negative Genetic
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 1 1 1 Dosage Growth Defect
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 1 1 1 Negative Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Negative Genetic
RPL35B YDL136W Ribosomal 60S subunit protein L35B genetic 1 1 1 Positive Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Positive Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Negative Genetic
HUT1 YPL244C Protein with a role in UDP-galactose transport to the Golgi lumen genetic 1 1 1 Positive Genetic
RCN1 YKL159C Protein involved in calcineurin regulation during calcium signaling genetic 1 1 1 Positive Genetic
SKY1 YMR216C SR protein kinase (SRPK) physical 1 1 1 Biochemical Activity
TOS3 YGL179C Protein kinase physical 1 1 1 Biochemical Activity
TOS3 YGL179C Protein kinase genetic 1 1 1 Positive Genetic
SET5 YHR207C Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 genetic 1 1 1 Synthetic Growth Defect
URN1 YPR152C Protein of unknown function containing WW and FF domains genetic 1 1 1 Negative Genetic
DOT5 YIL010W Nuclear thiol peroxidase genetic 1 1 1 Dosage Growth Defect
YBL086C YBL086C Protein of unknown function genetic 1 1 1 Positive Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
CWH43 YCR017C GPI lipid remodelase genetic 1 1 1 Positive Genetic
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Positive Genetic
YMD8 YML038C Putative nucleotide sugar transporter genetic 1 1 1 Negative Genetic
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Negative Genetic
TED1 YIL039W GPI-glycan remodelase genetic 1 1 1 Positive Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Dosage Growth Defect
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Positive Genetic
ITR1 YDR497C Myo-inositol transporter genetic 1 1 1 Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
ALG7 YBR243C UDP-N-acetyl-glucosamine-1-P transferase genetic 1 1 1 Dosage Growth Defect
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Positive Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Positive Genetic
YGR054W YGR054W Eukaryotic initiation factor eIF2A genetic 1 1 1 Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
SPC2 YML055W Subunit of signal peptidase complex genetic 1 1 1 Negative Genetic
VPS75 YNL246W NAP family histone chaperone genetic 1 1 1 Negative Genetic
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type genetic 1 1 1 Positive Genetic
RPI1 YIL119C Transcription factor, allelic differences between S288C and Sigma1278b genetic 1 1 1 Positive Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Synthetic Lethality
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Negative Genetic
RMD8 YFR048W Cytosolic protein required for sporulation genetic 1 1 1 Negative Genetic
SED4 YCR067C Integral ER membrane protein that stimulates Sar1p GTPase activity genetic 1 1 1 Negative Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Negative Genetic
SET6 YPL165C SET domain protein of unknown function genetic 1 1 1 Negative Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Positive Genetic
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Dosage Growth Defect
REX4 YOL080C Putative RNA exonuclease genetic 1 1 1 Positive Genetic
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Negative Genetic
YBP2 YGL060W Central kinetochore associated protein genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Positive Genetic
DSD1 YGL196W D-serine dehydratase (aka D-serine ammonia-lyase) genetic 1 1 1 Positive Genetic
REH1 YLR387C Cytoplasmic 60S subunit biogenesis factor genetic 1 1 1 Dosage Growth Defect
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Positive Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Negative Genetic
YND1 YER005W Apyrase with wide substrate specificity genetic 1 1 1 Positive Genetic
YFL040W YFL040W Putative transporter genetic 1 1 1 Dosage Growth Defect
HXT8 YJL214W Protein of unknown function with similarity to hexose transporters genetic 1 1 1 Negative Genetic
HXT17 YNR072W Putative transmembrane polyol transporter genetic 1 1 1 Negative Genetic
ALK2 YBL009W Atypical protein kinase genetic 1 1 1 Dosage Growth Defect
SMY2 YBR172C GYF domain protein genetic 1 1 1 Dosage Growth Defect
MAL32 YBR299W Maltase (alpha-D-glucosidase) genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Positive Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Positive Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Positive Genetic
HTC1 YPL067C Putative protein of unknown function genetic 1 1 1 Dosage Lethality
UFO1 YML088W F-box receptor protein genetic 1 1 1 Dosage Growth Defect
TBS1 YBR150C Protein of unknown function genetic 1 1 1 Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Negative Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Negative Genetic
YGL081W YGL081W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 1 1 1 Negative Genetic
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Positive Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Positive Genetic
HPM1 YIL110W AdoMet-dependent methyltransferase genetic 1 1 1 Negative Genetic
SPE4 YLR146C Spermine synthase genetic 1 1 1 Positive Genetic
SDT1 YGL224C Pyrimidine nucleotidase genetic 1 1 1 Positive Genetic
RAD61 YDR014W Subunit of a complex that inhibits sister chromatid cohesion genetic 1 1 1 Positive Genetic
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
MTC4 YBR255W Protein of unknown function genetic 1 1 1 Positive Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Positive Genetic
TSC10 YBR265W 3-ketosphinganine reductase genetic 1 1 1 Dosage Growth Defect
SRC1 YML034W Inner nuclear membrane protein genetic 1 1 1 Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Positive Genetic
IRS4 YKR019C EH domain-containing protein genetic 1 1 1 Negative Genetic
UBP12 YJL197W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes genetic 1 1 1 Negative Genetic
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Negative Genetic
TEP1 YNL128W PTEN homolog with no demonstrated inositol lipid phosphatase activity genetic 1 1 1 Positive Genetic
UBP11 YKR098C Ubiquitin-specific protease genetic 1 1 1 Positive Genetic
SHE10 YGL228W Protein involved in outer spore wall assembly genetic 1 1 1 Positive Genetic
YAR066W YAR066W Putative GPI protein genetic 1 1 1 Dosage Growth Defect
YML018C YML018C Protein of unknown function genetic 1 1 1 Dosage Growth Defect
YFL012W YFL012W Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
YCR050C YCR050C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic