Standard name Systematic name Name description Description
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family Conserved NAD+ dependent histone deacetylase of the Sirtuin family; deacetylation targets are primarily nuclear proteins; required for telomere hypercluster formation in quiescent yeast cells; involved in regulation of lifespan; plays roles in silencing at HML, HMR, telomeres, and rDNA; negatively regulates initiation of DNA replication; functions as regulator of autophagy like mammalian homolog SIRT1, and also of mitophagy
Visualize the interactome of SIR2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Endosome 0.098 0.116 0.079
Mito 0.199 NaN NaN
Nuc Periphery 0.236 0.303 0.288
Nucleolus 0.391 0.316 0.223
Nucleus 0.312 0.303 0.417
Vac/Vac Memb 0.058 0.142 0.094
SpindlePole NaN NaN 0.058

GFP localization & abundance

GFP localization GFP abundance
nuclear periphery 3350

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SIR2 4 1 0 0 1

Enzyme information

Catalyzed reactions in Yeast8
r_0767 (NAD nucleosidase nuclear)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains physical 34 6 27 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Reconstituted Complex, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Co-purification, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid
NET1 YJL076W Core subunit of the RENT complex physical 24 5 17 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-Western
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site genetic 18 4 17 Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression
HST1 YOL068C NAD(+)-dependent histone deacetylase genetic 11 4 11 Dosage Rescue, Phenotypic Enhancement, Synthetic Growth Defect, Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Enhancement
SIR3 YLR442C Silencing protein physical 11 5 9 Affinity Capture-Western, Affinity Capture-Western, Co-localization, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 10 4 6 Dosage Rescue, Dosage Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect, Synthetic Rescue
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 9 4 9 Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Dosage Rescue, Phenotypic Suppression, Phenotypic Suppression
HHF1 YBR009C Histone H4 physical 6 4 6 Biochemical Activity, Co-localization, Biochemical Activity, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 6 2 6 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression
HHT1 YBR010W Histone H3 physical 6 3 5 Biochemical Activity, Protein-peptide, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site physical 6 3 5 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid
HHT2 YNL031C Histone H3 physical 6 3 5 Biochemical Activity, Protein-peptide, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity
HHF2 YNL030W Histone H4 physical 5 3 5 Biochemical Activity, Co-localization, Biochemical Activity, Affinity Capture-Western, Biochemical Activity
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 5 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ASF1 YJL115W Nucleosome assembly factor genetic 5 3 4 Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Growth Defect
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 5 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family physical 4 4 4 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Co-crystal Structure
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 4 3 4 Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Suppression, Synthetic Rescue
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 4 2 3 Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue
RAD53 YPL153C DNA damage response kinase genetic 4 2 3 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue
MCM10 YIL150C Essential chromatin-associated protein physical 4 2 3 Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western
ESC2 YDR363W Sumo-like domain protein physical 4 1 3 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing physical 4 2 2 Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 3 3 3 Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Suppression
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex genetic 3 3 3 Synthetic Growth Defect, Synthetic Rescue, Phenotypic Suppression
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 3 3 3 Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression
HHF1 YBR009C Histone H4 genetic 3 2 3 Dosage Lethality, Dosage Rescue, Dosage Rescue
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex genetic 3 2 3 Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 3 2 3 Phenotypic Enhancement, Synthetic Rescue, Synthetic Rescue
SIR1 YKR101W Protein involved in silencing at mating-type loci HML and HMR physical 3 2 3 Co-localization, Affinity Capture-MS, Co-localization
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 3 3 2 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 3 3 2 Phenotypic Suppression, Synthetic Growth Defect, Synthetic Rescue
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 genetic 3 2 2 Dosage Rescue, Dosage Rescue, Phenotypic Suppression
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 3 2 2 Synthetic Growth Defect, Phenotypic Suppression, Synthetic Growth Defect
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 3 2 2 Synthetic Growth Defect, Phenotypic Suppression, Synthetic Growth Defect
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 3 2 2 Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK physical 3 2 1 Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
NSI1 YDR026C RNA polymerase I termination factor physical 3 2 1 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
CDC45 YLR103C DNA replication initiation factor genetic 2 2 2 Phenotypic Suppression, Synthetic Growth Defect
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 2 2 2 Phenotypic Suppression, Synthetic Growth Defect
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 2 2 2 Phenotypic Suppression, Phenotypic Enhancement
RAD52 YML032C Protein involved in homologous recombination genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains genetic 2 2 2 Phenotypic Suppression, Synthetic Rescue
SIR3 YLR442C Silencing protein genetic 2 2 2 Phenotypic Suppression, Synthetic Rescue
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins genetic 2 2 2 Synthetic Lethality, Synthetic Rescue
TIF2 YJL138C Translation initiation factor eIF4A genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
HTB1 YDR224C Histone H2B physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 2 2 2 Synthetic Rescue, Synthetic Growth Defect
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 2 2 2 Phenotypic Suppression, Phenotypic Enhancement
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
NFI1 YOR156C SUMO E3 ligase genetic 2 2 2 Phenotypic Suppression, Phenotypic Enhancement
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 2 2 2 Dosage Rescue, Phenotypic Suppression
RFM1 YOR279C Component of the Sum1p-Rfm1p-Hst1p complex physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RRN9 YMR270C Protein involved in promoting high level transcription of rDNA genetic 2 2 2 Synthetic Rescue, Phenotypic Enhancement
RTT109 YLL002W Histone acetyltransferase genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 2 2 2 Dosage Rescue, Synthetic Lethality
SCH9 YHR205W AGC family protein kinase genetic 2 2 2 Phenotypic Suppression, Phenotypic Enhancement
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
HHF2 YNL030W Histone H4 genetic 2 1 2 Dosage Rescue, Dosage Rescue
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
SIP2 YGL208W One of three alternate beta subunits of the Snf1 kinase complex genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CSM3 YMR048W Replication fork associated factor genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase physical 2 1 2 Co-localization, Co-localization
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 2 2 1 Dosage Rescue, Synthetic Rescue
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex physical 2 2 1 Two-hybrid, Reconstituted Complex
TDH1 YJL052W Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
TDH2 YJR009C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly physical 2 2 1 Two-hybrid, Reconstituted Complex
HIR1 YBL008W Subunit of the HIR complex genetic 2 2 1 Phenotypic Suppression, Phenotypic Enhancement
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 2 2 1 Phenotypic Enhancement, Phenotypic Suppression
RIF1 YBR275C Protein involved in control of DNA replication genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
MCM3 YEL032W Protein involved in DNA replication physical 2 2 1 Two-hybrid, Affinity Capture-Western
PBP1 YGR178C Component of glucose deprivation induced stress granules genetic 2 2 1 Phenotypic Enhancement, Phenotypic Suppression
ADA2 YDR448W Transcription coactivator physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
CMD1 YBR109C Calmodulin genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
HCM1 YCR065W Forkhead transcription factor physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase regulation 1 1 1 RNA-sequencing evidence
SER3 YER081W 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase regulation 1 1 1 RNA-sequencing evidence
SER1 YOR184W 3-phosphoserine aminotransferase regulation 1 1 1 RNA-sequencing evidence
ADI1 YMR009W Acireductone dioxygenease involved in methionine salvage pathway regulation 1 1 1 RNA-sequencing evidence
MET14 YKL001C Adenylylsulfate kinase regulation 1 1 1 RNA-sequencing evidence
AGA2 YGL032C Adhesion subunit of a-agglutinin of a-cells regulation 1 1 1 RNA-sequencing evidence
YPC1 YBR183W Alkaline ceramidase regulation 1 1 1 RNA-sequencing evidence
CAR1 YPL111W Arginase, catabolizes arginine to ornithine and urea regulation 1 1 1 RNA-sequencing evidence
ARO9 YHR137W Aromatic aminotransferase II regulation 1 1 1 RNA-sequencing evidence
BAR1 YIL015W Aspartyl protease secreted to periplasmic space of mating type a cell regulation 1 1 1 RNA-sequencing evidence
MET3 YJR010W ATP sulfurylase regulation 1 1 1 RNA-sequencing evidence
CHA1 YCL064C Catabolic L-serine (L-threonine) deaminase regulation 1 1 1 RNA-sequencing evidence
SUN4 YNL066W Cell wall protein related to glucanases localized in birth scars regulation 1 1 1 RNA-sequencing evidence
MHF2 YDL160C-A Component of the heterotetrameric MHF histone-fold complex regulation 1 1 1 RNA-sequencing evidence
TOS1 YBR162C Covalently-bound cell wall protein of unknown function regulation 1 1 1 RNA-sequencing evidence
CYB5 YNL111C Cytochrome b5 regulation 1 1 1 RNA-sequencing evidence
CYT1 YOR065W Cytochrome c1 regulation 1 1 1 RNA-sequencing evidence
CYC1 YJR048W Cytochrome c, isoform 1 regulation 1 1 1 RNA-sequencing evidence
CYC7 YEL039C Cytochrome c isoform 2, expressed under hypoxic conditions regulation 1 1 1 RNA-sequencing evidence
COA2 YPL189C-A Cytochrome oxidase assembly factor regulation 1 1 1 RNA-sequencing evidence
HUA2 YOR284W Cytoplasmic protein of unknown function regulation 1 1 1 RNA-sequencing evidence
ERG6 YML008C Delta(24)-sterol C-methyltransferase regulation 1 1 1 RNA-sequencing evidence
GPP2 YER062C DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis regulation 1 1 1 RNA-sequencing evidence
RDH54 YBR073W DNA-dependent ATPase regulation 1 1 1 RNA-sequencing evidence
NEJ1 YLR265C DNA end-binding protein required for nonhomologous end joining (NHEJ) regulation 1 1 1 RNA-sequencing evidence
YNL337W YNL337W Dubious open reading frame regulation 1 1 1 RNA-sequencing evidence
YCL076W YCL076W Dubious open reading frame regulation 1 1 1 RNA-sequencing evidence
YFL063W YFL063W Dubious open reading frame regulation 1 1 1 RNA-sequencing evidence
YCR097W-A YCR097W-A Dubious open reading frame regulation 1 1 1 RNA-sequencing evidence
YCL065W YCL065W Dubious open reading frame regulation 1 1 1 RNA-sequencing evidence
YGR182C YGR182C Dubious open reading frame regulation 1 1 1 RNA-sequencing evidence
COS1 YNL336W Endosomal protein involved in turnover of plasma membrane proteins regulation 1 1 1 RNA-sequencing evidence
COS4 YFL062W Endosomal protein involved in turnover of plasma membrane proteins regulation 1 1 1 RNA-sequencing evidence
COS8 YHL048W Endosomal protein involved in turnover of plasma membrane proteins regulation 1 1 1 RNA-sequencing evidence
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins regulation 1 1 1 RNA-sequencing evidence
YNR064C YNR064C Epoxide hydrolase regulation 1 1 1 RNA-sequencing evidence
HMX1 YLR205C ER localized heme oxygenase regulation 1 1 1 RNA-sequencing evidence
STE14 YDR410C Farnesyl cysteine-carboxyl methyltransferase regulation 1 1 1 RNA-sequencing evidence
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle regulation 1 1 1 RNA-sequencing evidence
STE4 YOR212W G protein beta subunit regulation 1 1 1 RNA-sequencing evidence
STE18 YJR086W G protein gamma subunit regulation 1 1 1 RNA-sequencing evidence
SST2 YLR452C GTPase-activating protein for Gpa1p regulation 1 1 1 RNA-sequencing evidence
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone regulation 1 1 1 RNA-sequencing evidence
YGL193C YGL193C Haploid-specific gene repressed by a1-alpha2 regulation 1 1 1 RNA-sequencing evidence
HPF1 YOL155C Haze-protective mannoprotein regulation 1 1 1 RNA-sequencing evidence
ROX1 YPR065W Heme-dependent repressor of hypoxic genes regulation 1 1 1 RNA-sequencing evidence
MMP1 YLL061W High-affinity S-methylmethionine permease regulation 1 1 1 RNA-sequencing evidence
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane regulation 1 1 1 RNA-sequencing evidence
MPC3 YGR243W Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) regulation 1 1 1 RNA-sequencing evidence
IMD2 YHR216W Inosine monophosphate dehydrogenase regulation 1 1 1 RNA-sequencing evidence
AXL2 YIL140W Integral plasma membrane protein regulation 1 1 1 RNA-sequencing evidence
IDI1 YPL117C Isopentenyl diphosphate:dimethylallyl diphosphate isomerase regulation 1 1 1 RNA-sequencing evidence
BNA5 YLR231C Kynureninase regulation 1 1 1 RNA-sequencing evidence
BNA4 YBL098W Kynurenine 3-monooxygenase regulation 1 1 1 RNA-sequencing evidence
DLD1 YDL174C Major mitochondrial D-lactate dehydrogenase regulation 1 1 1 RNA-sequencing evidence
MFA2 YNL145W Mating pheromone a-factor regulation 1 1 1 RNA-sequencing evidence
MFA1 YDR461W Mating pheromone a-factor regulation 1 1 1 RNA-sequencing evidence
YLR460C YLR460C Member of the quinone oxidoreductase family regulation 1 1 1 RNA-sequencing evidence
PAU4 YLR461W Member of the seripauperin multigene family regulation 1 1 1 RNA-sequencing evidence
HSP31 YDR533C Methylglyoxalase that converts methylglyoxal to D-lactate regulation 1 1 1 RNA-sequencing evidence
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase regulation 1 1 1 RNA-sequencing evidence
NDE1 YMR145C Mitochondrial external NADH dehydrogenase regulation 1 1 1 RNA-sequencing evidence
CRC1 YOR100C Mitochondrial inner membrane carnitine transporter regulation 1 1 1 RNA-sequencing evidence
MCR1 YKL150W Mitochondrial NADH-cytochrome b5 reductase regulation 1 1 1 RNA-sequencing evidence
PRX1 YBL064C Mitochondrial peroxiredoxin with thioredoxin peroxidase activity regulation 1 1 1 RNA-sequencing evidence
SFC1 YJR095W Mitochondrial succinate-fumarate transporter regulation 1 1 1 RNA-sequencing evidence
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating regulation 1 1 1 RNA-sequencing evidence
AMN1 YBR158W Modulator of cell separation and mitotic exit regulation 1 1 1 RNA-sequencing evidence
IME4 YGL192W mRNA N6-adenosine methyltransferase regulation 1 1 1 RNA-sequencing evidence
DDR2 YOL052C-A Multi-stress response protein regulation 1 1 1 RNA-sequencing evidence
FDH1 YOR388C NAD(+)-dependent formate dehydrogenase regulation 1 1 1 RNA-sequencing evidence
ADH7 YCR105W NADPH-dependent medium chain alcohol dehydrogenase regulation 1 1 1 RNA-sequencing evidence
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway regulation 1 1 1 RNA-sequencing evidence
YAR075W YAR075W Non-functional protein with homology IMP dehydrogenase regulation 1 1 1 RNA-sequencing evidence
IMD1 YAR073W Nonfunctional protein with homology to IMP dehydrogenase regulation 1 1 1 RNA-sequencing evidence
GTO3 YMR251W Omega class glutathione transferase regulation 1 1 1 RNA-sequencing evidence
PLN1 YKR046C Perilipin, involved in formation and stability of lipid droplets regulation 1 1 1 RNA-sequencing evidence
VBA2 YBR293W Permease of basic amino acids in the vacuolar membrane regulation 1 1 1 RNA-sequencing evidence
VBA3 YCL069W Permease of basic amino acids in the vacuolar membrane regulation 1 1 1 RNA-sequencing evidence
STE5 YDR103W Pheromone-responsive MAPK scaffold protein regulation 1 1 1 RNA-sequencing evidence
ERG8 YMR220W Phosphomevalonate kinase regulation 1 1 1 RNA-sequencing evidence
STE6 YKL209C Plasma membrane ATP-binding cassette (ABC) transporter regulation 1 1 1 RNA-sequencing evidence
PMA1 YGL008C Plasma membrane P2-type H+-ATPase regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
HSP12 YFL014W Plasma membrane protein involved in maintaining membrane organization regulation 1 1 1 RNA-sequencing evidence
JID1 YPR061C Probable Hsp40p co-chaperone regulation 1 1 1 RNA-sequencing evidence
YDR018C YDR018C Probable membrane protein with three predicted transmembrane domains regulation 1 1 1 RNA-sequencing evidence
PUT4 YOR348C Proline permease regulation 1 1 1 RNA-sequencing evidence
NCA3 YJL116C Protein involved in mitochondrion organization regulation 1 1 1 RNA-sequencing evidence
NSG2 YNL156C Protein involved in regulation of sterol biosynthesis regulation 1 1 1 RNA-sequencing evidence
THI5 YFL058W Protein involved in synthesis of the thiamine precursor HMP regulation 1 1 1 RNA-sequencing evidence
YER053C-A YER053C-A Protein of unknown function regulation 1 1 1 RNA-sequencing evidence
SNO3 YFL060C Protein of unknown function regulation 1 1 1 RNA-sequencing evidence
ICS2 YBR157C Protein of unknown function regulation 1 1 1 RNA-sequencing evidence
ICY1 YMR195W Protein of unknown function regulation 1 1 1 RNA-sequencing evidence
YKR075C YKR075C Protein of unknown function regulation 1 1 1 RNA-sequencing evidence
CMC4 YMR194C-B Protein that localizes to the mitochondrial intermembrane space regulation 1 1 1 RNA-sequencing evidence
YPS5 YGL259W Protein with similarity to GPI-anchored aspartic proteases regulation 1 1 1 RNA-sequencing evidence
GEX1 YCL073C Proton:glutathione antiporter regulation 1 1 1 RNA-sequencing evidence
PDH1 YPR002W Putative 2-methylcitrate dehydratase regulation 1 1 1 RNA-sequencing evidence
AAD15 YOL165C Putative aryl-alcohol dehydrogenase regulation 1 1 1 RNA-sequencing evidence
YBR284W YBR284W Putative metallo-dependent hydrolase superfamily protein regulation 1 1 1 RNA-sequencing evidence
DPI8 YJL133C-A Putative mitochondrial protein of unknown function regulation 1 1 1 RNA-sequencing evidence
YJL047C-A YJL047C-A Putative protein of unknown function regulation 1 1 1 RNA-sequencing evidence
YCL068C YCL068C Putative protein of unknown function regulation 1 1 1 RNA-sequencing evidence
YFR057W YFR057W Putative protein of unknown function regulation 1 1 1 RNA-sequencing evidence
YGL258W-A YGL258W-A Putative protein of unknown function regulation 1 1 1 RNA-sequencing evidence
YIL014C-A YIL014C-A Putative protein of unknown function regulation 1 1 1 RNA-sequencing evidence
YDR042C YDR042C Putative protein of unknown function regulation 1 1 1 RNA-sequencing evidence
YMR206W YMR206W Putative protein of unknown function regulation 1 1 1 RNA-sequencing evidence
YPR027C YPR027C Putative protein of unknown function regulation 1 1 1 RNA-sequencing evidence
YJR115W YJR115W Putative protein of unknown function regulation 1 1 1 RNA-sequencing evidence
STE2 YFL026W Receptor for alpha-factor pheromone regulation 1 1 1 RNA-sequencing evidence
YDR034C-D YDR034C-D Retrotransposon TYA Gag and TYB Pol genes regulation 1 1 1 RNA-sequencing evidence
YDR170W-A YDR170W-A Retrotransposon TYA Gag gene regulation 1 1 1 RNA-sequencing evidence
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly regulation 1 1 1 RNA-sequencing evidence
REX3 YLR107W RNA exonuclease regulation 1 1 1 RNA-sequencing evidence
HMRA1 YCR097W Silenced copy of a1 at HMR regulation 1 1 1 RNA-sequencing evidence
HMRA2 YCR096C Silenced copy of a2 at HMR regulation 1 1 1 RNA-sequencing evidence
HMLALPHA1 YCL066W Silenced copy of ALPHA1 at HML regulation 1 1 1 RNA-sequencing evidence
HMLALPHA2 YCL067C Silenced copy of ALPHA2 at HML regulation 1 1 1 RNA-sequencing evidence
HO YDL227C Site-specific endonuclease regulation 1 1 1 RNA-sequencing evidence
RDT1 YCL054W-A Small gene in the chromosome III recombination enhancer regulation 1 1 1 transcript expression evidence
RSB1 YOR049C Sphingoid long-chain base (LCB) efflux transporter regulation 1 1 1 RNA-sequencing evidence
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) regulation 1 1 1 RNA-sequencing evidence
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex regulation 1 1 1 RNA-sequencing evidence
QCR7 YDR529C Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) regulation 1 1 1 RNA-sequencing evidence
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) regulation 1 1 1 RNA-sequencing evidence
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) regulation 1 1 1 RNA-sequencing evidence
MET10 YFR030W Subunit alpha of assimilatory sulfite reductase regulation 1 1 1 RNA-sequencing evidence
COX26 YDR119W-A Subunit of cytochrome C oxidase complex regulation 1 1 1 RNA-sequencing evidence
GPA1 YHR005C Subunit of G protein involved in pheromone response regulation 1 1 1 RNA-sequencing evidence
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase regulation 1 1 1 RNA-sequencing evidence
QCR10 YHR001W-A Subunit of the ubiqunol-cytochrome c oxidoreductase complex regulation 1 1 1 RNA-sequencing evidence
COX5A YNL052W Subunit Va of cytochrome c oxidase regulation 1 1 1 RNA-sequencing evidence
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) regulation 1 1 1 RNA-sequencing evidence
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) regulation 1 1 1 RNA-sequencing evidence
AHP1 YLR109W Thiol-specific peroxiredoxin regulation 1 1 1 RNA-sequencing evidence
HAP4 YKL109W Transcription factor regulation 1 1 1 RNA-sequencing evidence
ATG39 YLR312C Transmembrane receptor with a role in nucleophagy regulation 1 1 1 RNA-sequencing evidence
TGL2 YDR058C Triacylglycerol lipase that is localized to the mitochondria regulation 1 1 1 RNA-sequencing evidence
BNA2 YJR078W Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase regulation 1 1 1 RNA-sequencing evidence
UBX6 YJL048C UBX (ubiquitin regulatory X) domain-containing protein regulation 1 1 1 RNA-sequencing evidence
RME1 YGR044C Zinc finger protein involved in control of meiosis regulation 1 1 1 RNA-sequencing evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Phenotypic Enhancement
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Synthetic Growth Defect
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Phenotypic Suppression
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 1 1 1 Phenotypic Enhancement
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly genetic 1 1 1 Synthetic Growth Defect
ERB1 YMR049C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
NOP16 YER002W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Synthetic Growth Defect
ADH1 YOL086C Alcohol dehydrogenase physical 1 1 1 Affinity Capture-MS
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Synthetic Growth Defect
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 1 1 1 Synthetic Rescue
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex genetic 1 1 1 Synthetic Growth Defect
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Phenotypic Enhancement
CDC33 YOL139C Translation initiation factor eIF4E genetic 1 1 1 Synthetic Growth Defect
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Synthetic Growth Defect
DIS3 YOL021C Exosome core complex catalytic subunit genetic 1 1 1 Synthetic Growth Defect
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Synthetic Growth Defect
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Phenotypic Enhancement
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Synthetic Growth Defect
RPC19 YNL113W RNA polymerase subunit AC19 physical 1 1 1 Affinity Capture-MS
RPO31 YOR116C RNA polymerase III largest subunit C160 physical 1 1 1 Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 1 1 1 Affinity Capture-Western
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Phenotypic Suppression
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-Western
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Synthetic Growth Defect
HPR1 YDR138W Subunit of THO/TREX complexes genetic 1 1 1 Phenotypic Enhancement
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Rescue
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Enhancement
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Phenotypic Suppression
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Synthetic Growth Defect
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Synthetic Growth Defect
KAP95 YLR347C Karyopherin beta physical 1 1 1 Affinity Capture-MS
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Synthetic Growth Defect
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Phenotypic Enhancement
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Synthetic Growth Defect
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Synthetic Growth Defect
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Phenotypic Enhancement
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Synthetic Growth Defect
BNI1 YNL271C Formin genetic 1 1 1 Synthetic Growth Defect
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Synthetic Growth Defect
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Synthetic Growth Defect
CNS1 YBR155W TPR-containing co-chaperone genetic 1 1 1 Synthetic Growth Defect
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Synthetic Growth Defect
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Phenotypic Suppression
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator genetic 1 1 1 Phenotypic Enhancement
DPB4 YDR121W Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex genetic 1 1 1 Phenotypic Suppression
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Synthetic Growth Defect
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex physical 1 1 1 Co-localization
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Two-hybrid
MCM6 YGL201C Protein involved in DNA replication physical 1 1 1 Two-hybrid
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Enhancement
MED2 YDL005C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Enhancement
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Phenotypic Suppression
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Phenotypic Suppression
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Synthetic Growth Defect
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Synthetic Growth Defect
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
NHP6B YBR089C-A High-mobility group (HMG) protein genetic 1 1 1 Phenotypic Suppression
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Phenotypic Suppression
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Two-hybrid
HTA1 YDR225W Histone H2A physical 1 1 1 Affinity Capture-Western
PRP21 YJL203W Subunit of the SF3a splicing factor complex genetic 1 1 1 Synthetic Growth Defect
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Phenotypic Enhancement
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Synthetic Growth Defect
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Synthetic Growth Defect
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
RPB10 YOR210W RNA polymerase subunit ABC10-beta physical 1 1 1 Affinity Capture-MS
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
RPL23A YBL087C Ribosomal 60S subunit protein L23A genetic 1 1 1 Phenotypic Suppression
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Dosage Rescue
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Phenotypic Suppression
SAM1 YLR180W S-adenosylmethionine synthetase genetic 1 1 1 Phenotypic Suppression
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Synthetic Growth Defect
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Phenotypic Enhancement
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Phenotypic Suppression
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Phenotypic Suppression
BGL2 YGR282C Endo-beta-1,3-glucanase physical 1 1 1 Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-MS
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth physical 1 1 1 Two-hybrid
ZDS2 YML109W Protein with a role in regulating Swe1p-dependent polarized growth physical 1 1 1 Two-hybrid
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes physical 1 1 1 Affinity Capture-Western
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Protein-RNA
SKA1 YKL023W SKI complex-associated protein physical 1 1 1 Affinity Capture-MS
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
TOP1 YOL006C Topoisomerase I physical 1 1 1 Affinity Capture-Western
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Growth Defect
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-Western
SMC6 YLR383W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Phenotypic Enhancement
SPO13 YHR014W Meiotic regulator genetic 1 1 1 Synthetic Rescue
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Dosage Rescue
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Synthetic Growth Defect
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Synthetic Growth Defect
SRC1 YML034W Inner nuclear membrane protein genetic 1 1 1 Phenotypic Enhancement
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Synthetic Growth Defect
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Synthetic Growth Defect
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Synthetic Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
SSA2 YLL024C HSP70 family ATP-binding protein genetic 1 1 1 Synthetic Growth Defect
SLX9 YGR081C Protein required for pre-rRNA processing genetic 1 1 1 Synthetic Growth Defect
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Synthetic Growth Defect
SSD1 YDR293C Translational repressor genetic 1 1 1 Synthetic Growth Defect
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Synthetic Growth Defect
TWF1 YGR080W Twinfilin genetic 1 1 1 Synthetic Growth Defect
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p genetic 1 1 1 Synthetic Growth Defect
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Synthetic Growth Defect
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Synthetic Growth Defect
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Synthetic Growth Defect
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
SRO9 YCL037C Cytoplasmic RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
SVP26 YHR181W ER exit adaptor for Golgi mannosyltransferases genetic 1 1 1 Synthetic Growth Defect
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Synthetic Growth Defect
SPH1 YLR313C Protein involved in shmoo formation and bipolar bud site selection genetic 1 1 1 Synthetic Growth Defect
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Synthetic Growth Defect
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Synthetic Growth Defect
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Synthetic Growth Defect
SPR28 YDR218C Sporulation-specific homolog of the CDC3/10/11/12 family of genes genetic 1 1 1 Synthetic Growth Defect
YGL081W YGL081W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SOD2 YHR008C Mitochondrial manganese superoxide dismutase genetic 1 1 1 Synthetic Growth Defect
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Synthetic Growth Defect
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Synthetic Growth Defect
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Synthetic Growth Defect
TIR1 YER011W Cell wall mannoprotein genetic 1 1 1 Synthetic Growth Defect
SND3 YBR106W Involved in SRP-independent protein targeting to the ER genetic 1 1 1 Synthetic Growth Defect
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Synthetic Growth Defect
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Synthetic Growth Defect
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Synthetic Growth Defect
SPS1 YDR523C STE20-family GCKIII protein kinase genetic 1 1 1 Phenotypic Suppression
TIS11 YLR136C mRNA-binding protein expressed during iron starvation genetic 1 1 1 Phenotypic Suppression
TMA19 YKL056C Protein that associates with ribosomes genetic 1 1 1 Phenotypic Suppression
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Phenotypic Suppression
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Phenotypic Suppression
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Phenotypic Suppression
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Enhancement
UTH1 YKR042W Mitochondrial inner membrane protein genetic 1 1 1 Phenotypic Suppression
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 1 1 1 Phenotypic Suppression
SLD7 YOR060C Protein with a role in chromosomal DNA replication genetic 1 1 1 Phenotypic Suppression
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties genetic 1 1 1 Phenotypic Suppression
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Synthetic Growth Defect
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Synthetic Growth Defect
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Synthetic Growth Defect
SMC2 YFR031C Subunit of the condensin complex genetic 1 1 1 Synthetic Growth Defect
TFC1 YBR123C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Synthetic Growth Defect
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Phenotypic Suppression
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 1 1 1 Synthetic Growth Defect
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Synthetic Rescue
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Synthetic Growth Defect
MIP6 YHR015W Putative RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
CRN1 YLR429W Coronin genetic 1 1 1 Synthetic Growth Defect
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Synthetic Growth Defect
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Synthetic Growth Defect
MCM2 YBL023C Protein involved in DNA replication genetic 1 1 1 Synthetic Rescue
SAW1 YAL027W 5'- and 3'-flap DNA binding protein genetic 1 1 1 Phenotypic Enhancement
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex physical 1 1 1 Co-localization
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Growth Defect
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization physical 1 1 1 Affinity Capture-MS
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton genetic 1 1 1 Synthetic Growth Defect
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor physical 1 1 1 Affinity Capture-MS
MDH1 YKL085W Mitochondrial malate dehydrogenase genetic 1 1 1 Phenotypic Suppression
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Synthetic Growth Defect
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Phenotypic Suppression
HTB1 YDR224C Histone H2B genetic 1 1 1 Synthetic Rescue
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Synthetic Growth Defect
SEC53 YFL045C Phosphomannomutase genetic 1 1 1 Synthetic Growth Defect
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector physical 1 1 1 Affinity Capture-MS
RAD55 YDR076W Protein that stimulates strand exchange genetic 1 1 1 Synthetic Growth Defect
HSP104 YLL026W Disaggregase genetic 1 1 1 Dosage Rescue
ARG4 YHR018C Argininosuccinate lyase genetic 1 1 1 Synthetic Growth Defect
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Synthetic Growth Defect
AIP1 YMR092C Actin cortical patch component genetic 1 1 1 Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Dosage Rescue
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Synthetic Growth Defect
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Phenotypic Suppression
RSN1 YMR266W Membrane protein of unknown function genetic 1 1 1 Synthetic Growth Defect
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 1 1 1 Synthetic Growth Defect
HHT1 YBR010W Histone H3 genetic 1 1 1 Phenotypic Suppression
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Synthetic Growth Defect
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p physical 1 1 1 Two-hybrid
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Phenotypic Enhancement
AIR1 YIL079C Zinc knuckle protein genetic 1 1 1 Synthetic Growth Defect
MAS2 YHR024C Alpha subunit of the mitochondrial processing protease (MPP) genetic 1 1 1 Synthetic Growth Defect
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Synthetic Growth Defect
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Synthetic Growth Defect
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Phenotypic Suppression
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Synthetic Growth Defect
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Synthetic Growth Defect
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Synthetic Growth Defect
RAD26 YJR035W Protein involved in transcription-coupled nucleotide excision repair genetic 1 1 1 Synthetic Rescue
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 1 1 1 Synthetic Growth Defect
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
FMP48 YGR052W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
BIL2 YGL015C Formin inhibitor genetic 1 1 1 Synthetic Growth Defect
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I physical 1 1 1 Co-localization
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Phenotypic Enhancement
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Synthetic Growth Defect
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Synthetic Growth Defect
RRN6 YBL014C Component of the core factor (CF) rDNA transcription factor complex genetic 1 1 1 Synthetic Rescue
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Phenotypic Enhancement
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Synthetic Growth Defect
NHP6A YPR052C High-mobility group (HMG) protein genetic 1 1 1 Phenotypic Suppression
SAC3 YDR159W mRNA export factor genetic 1 1 1 Synthetic Growth Defect
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) genetic 1 1 1 Phenotypic Suppression
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Dosage Rescue
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Phenotypic Enhancement
RIF1 YBR275C Protein involved in control of DNA replication physical 1 1 1 Affinity Capture-MS
ATG8 YBL078C Ub-like protein genetic 1 1 1 Synthetic Growth Defect
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Synthetic Growth Defect
HOP1 YIL072W Meiosis-specific protein required for chromosome synapsis genetic 1 1 1 Phenotypic Suppression
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Synthetic Growth Defect
PEA2 YER149C Coiled-coil 12S polarisome subunit genetic 1 1 1 Synthetic Growth Defect
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Phenotypic Enhancement
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Synthetic Growth Defect
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Synthetic Growth Defect
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Synthetic Growth Defect
HRB1 YNL004W Poly(A+) RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family genetic 1 1 1 Synthetic Rescue
FBP1 YLR377C Fructose-1,6-bisphosphatase genetic 1 1 1 Phenotypic Enhancement
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Synthetic Growth Defect
BUD6 YLR319C Actin- and formin-interacting protein genetic 1 1 1 Synthetic Growth Defect
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Two-hybrid
AFI1 YOR129C Arf3p polarization-specific docking factor genetic 1 1 1 Synthetic Growth Defect
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Phenotypic Enhancement
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 1 1 1 Affinity Capture-MS
SCD5 YOR329C Protein required for normal actin organization and endocytosis genetic 1 1 1 Synthetic Growth Defect
ORC5 YNL261W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Synthetic Rescue
MSB3 YNL293W Rab GTPase-activating protein genetic 1 1 1 Synthetic Growth Defect
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 1 1 1 Synthetic Growth Defect
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p physical 1 1 1 Co-localization
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Phenotypic Enhancement
HHT2 YNL031C Histone H3 genetic 1 1 1 Phenotypic Suppression
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Phenotypic Suppression
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Synthetic Growth Defect
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
INP51 YIL002C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Phenotypic Suppression
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Phenotypic Suppression
RPS23B YPR132W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
RPL13A YDL082W Ribosomal 60S subunit protein L13A genetic 1 1 1 Phenotypic Suppression
RPL7A YGL076C Ribosomal 60S subunit protein L7A genetic 1 1 1 Phenotypic Suppression
RTN1 YDR233C Reticulon protein physical 1 1 1 Affinity Capture-MS
RTN1 YDR233C Reticulon protein genetic 1 1 1 Synthetic Growth Defect
KIP1 YBL063W Kinesin-related motor protein genetic 1 1 1 Synthetic Growth Defect
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes physical 1 1 1 Biochemical Activity
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Phenotypic Suppression
JHD2 YJR119C JmjC domain family histone demethylase genetic 1 1 1 Phenotypic Enhancement
SEC8 YPR055W Essential 121 kDa subunit of the exocyst complex genetic 1 1 1 Synthetic Growth Defect
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) genetic 1 1 1 Synthetic Growth Defect
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 1 1 1 Phenotypic Suppression
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Synthetic Growth Defect
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B genetic 1 1 1 Phenotypic Suppression
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase physical 1 1 1 Affinity Capture-Western
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Synthetic Growth Defect
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 1 1 1 Phenotypic Suppression
FLO11 YIR019C GPI-anchored cell surface glycoprotein (flocculin) genetic 1 1 1 Phenotypic Suppression
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Synthetic Growth Defect
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Synthetic Growth Defect
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Synthetic Growth Defect
RPL35B YDL136W Ribosomal 60S subunit protein L35B genetic 1 1 1 Phenotypic Suppression
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
LAG1 YHL003C Ceramide synthase component genetic 1 1 1 Synthetic Growth Defect
HST4 YDR191W NAD(+)-dependent protein deacetylase genetic 1 1 1 Synthetic Growth Defect
NEJ1 YLR265C DNA end-binding protein required for nonhomologous end joining (NHEJ) genetic 1 1 1 Dosage Rescue
RTT106 YNL206C Histone chaperone genetic 1 1 1 Phenotypic Suppression
PCK1 YKR097W Phosphoenolpyruvate carboxykinase physical 1 1 1 Biochemical Activity
PCK1 YKR097W Phosphoenolpyruvate carboxykinase genetic 1 1 1 Phenotypic Suppression
PKP2 YGL059W Mitochondrial protein kinase genetic 1 1 1 Synthetic Growth Defect
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Synthetic Growth Defect
EST2 YLR318W Reverse transcriptase subunit of the telomerase holoenzyme genetic 1 1 1 Synthetic Growth Defect
PNC1 YGL037C Nicotinamidase that converts nicotinamide to nicotinic acid genetic 1 1 1 Phenotypic Suppression
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Synthetic Growth Defect
RCR2 YDR003W Vacuolar ubiquitin ligase-substrate adaptor genetic 1 1 1 Synthetic Growth Defect
MPS3 YJL019W Nuclear envelope protein genetic 1 1 1 Synthetic Growth Defect
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Synthetic Growth Defect
GRX3 YDR098C Glutathione-dependent oxidoreductase physical 1 1 1 Affinity Capture-Western
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Synthetic Growth Defect
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER genetic 1 1 1 Phenotypic Suppression
RMR1 YGL250W Protein required for meiotic recombination and gene conversion genetic 1 1 1 Synthetic Growth Defect
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase physical 1 1 1 Affinity Capture-MS
NAT4 YMR069W N alpha-acetyl-transferase genetic 1 1 1 Phenotypic Suppression
MSC1 YML128C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Synthetic Growth Defect
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Synthetic Growth Defect
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Phenotypic Suppression
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease genetic 1 1 1 Synthetic Growth Defect
HST2 YPL015C Cytoplasmic NAD(+)-dependent protein deacetylase genetic 1 1 1 Phenotypic Enhancement
RPL37B YDR500C Ribosomal 60S subunit protein L37B genetic 1 1 1 Phenotypic Suppression
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Phenotypic Enhancement
NRK1 YNL129W Nicotinamide riboside kinase genetic 1 1 1 Synthetic Lethality
AAT1 YKL106W Mitochondrial aspartate aminotransferase genetic 1 1 1 Phenotypic Suppression
MTC4 YBR255W Protein of unknown function genetic 1 1 1 Phenotypic Suppression
MSW1 YDR268W Mitochondrial tryptophanyl-tRNA synthetase genetic 1 1 1 Phenotypic Suppression
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Synthetic Growth Defect
IRS4 YKR019C EH domain-containing protein genetic 1 1 1 Phenotypic Enhancement
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Synthetic Growth Defect