Standard name Systematic name Name description Description
RRP6 YOR001W Nuclear exosome exonuclease component Nuclear exosome exonuclease component; has 3'-5' exonuclease activity that is regulated by Lrp1p; involved in RNA processing, maturation, surveillance, degradation, tethering, and export; role in sn/snoRNAs precursor degradation; forms a stable heterodimer with Lrp1p; has similarity to E. coli RNase D and to human PM-Sc1 100 (EXOSC10); mutant displays reduced transcription elongation in the G-less-based
Visualize the interactome of RRP6
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.300 0.317 0.094
Nucleus 0.771 0.714 0.886
Mito NaN 0.119 NaN

GFP localization & abundance

GFP localization GFP abundance
nucleolus, nucleus 2160

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RRP6 47 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein physical 19 6 17 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Co-purification, Co-crystal Structure, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS
DIS3 YOL021C Exosome core complex catalytic subunit physical 16 4 13 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
RRP4 YHR069C Exosome non-catalytic core component physical 15 5 13 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
CSL4 YNL232W Exosome non-catalytic core component physical 15 4 13 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
SKI6 YGR195W Exosome non-catalytic core component physical 15 4 13 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
RRP45 YDR280W Exosome non-catalytic core component physical 15 4 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
RRP43 YCR035C Exosome non-catalytic core component physical 14 4 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS
RRP46 YGR095C Exosome non-catalytic core component physical 14 4 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
RRP42 YDL111C Exosome non-catalytic core component physical 12 4 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
RRP40 YOL142W Exosome non-catalytic core component physical 12 4 10 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
MPP6 YNR024W Nuclear exosome-associated RNA binding protein physical 12 5 8 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS
MTR3 YGR158C Exosome non-catalytic core component physical 10 4 9 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
DIS3 YOL021C Exosome core complex catalytic subunit genetic 8 4 8 Dosage Rescue, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect
SRP1 YNL189W Karyopherin alpha homolog physical 8 2 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export genetic 7 5 6 Synthetic Lethality, Synthetic Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Dosage Growth Defect, Negative Genetic
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 7 4 6 Phenotypic Enhancement, Synthetic Lethality, Phenotypic Enhancement, Synthetic Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression
MTR4 YJL050W RNA duplex-sensing translocase physical 6 4 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Co-purification
KAP95 YLR347C Karyopherin beta physical 6 1 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 6 2 5 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SAC3 YDR159W mRNA export factor genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MTR4 YJL050W RNA duplex-sensing translocase genetic 6 4 4 Dosage Rescue, Synthetic Growth Defect, Dosage Rescue, Synthetic Lethality, Synthetic Rescue, Synthetic Rescue
MPP6 YNR024W Nuclear exosome-associated RNA binding protein genetic 5 4 5 Negative Genetic, Dosage Rescue, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
NRD1 YNL251C RNA-binding subunit of Nrd1 complex physical 5 2 5 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
RPA14 YDR156W RNA polymerase I subunit A14 genetic 5 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 5 4 4 Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Rescue, Synthetic Rescue
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 5 4 4 Synthetic Growth Defect, Positive Genetic, Positive Genetic, Phenotypic Suppression, Dosage Rescue
MFT1 YML062C Subunit of the THO complex genetic 5 3 4 Synthetic Rescue, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic
RNH70 YGR276C 3'-5' exoribonuclease genetic 5 2 4 Dosage Rescue, Negative Genetic, Dosage Rescue, Negative Genetic, Negative Genetic
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex genetic 5 4 3 Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Suppression, Negative Genetic
SKI6 YGR195W Exosome non-catalytic core component genetic 4 3 4 Phenotypic Enhancement, Negative Genetic, Synthetic Lethality, Negative Genetic
PAP1 YKR002W Poly(A) polymerase genetic 4 3 4 Synthetic Rescue, Phenotypic Suppression, Phenotypic Enhancement, Synthetic Rescue
YPT6 YLR262C Rab family GTPase genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome physical 4 3 3 Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 4 3 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Phenotypic Enhancement
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 3 3 3 Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Lethality
RNA14 YMR061W Component of the cleavage and polyadenylation factor I (CF I) genetic 3 3 3 Synthetic Rescue, Phenotypic Suppression, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 3 2 3 Negative Genetic, Positive Genetic, Negative Genetic
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 3 2 3 Negative Genetic, Phenotypic Enhancement, Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 3 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression
RRP6 YOR001W Nuclear exosome exonuclease component physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
STB5 YHR178W Transcription factor genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
HPR1 YDR138W Subunit of THO/TREX complexes genetic 3 3 2 Synthetic Growth Defect, Synthetic Rescue, Phenotypic Suppression
PCF11 YDR228C mRNA 3' end processing factor genetic 3 3 2 Synthetic Growth Defect, Positive Genetic, Negative Genetic
NOT5 YPR072W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 3 3 2 Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Lethality
TRM8 YDL201W Catalytic subunit of a tRNA methyltransferase complex genetic 3 2 2 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
NOP53 YPL146C Nucleolar protein physical 3 2 2 Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RSA3 YLR221C Protein with a likely role in ribosomal maturation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PUF6 YDR496C Pumilio-homology domain protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) physical 3 1 2 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
LSM1 YJL124C Lsm (Like Sm) protein genetic 2 2 2 Positive Genetic, Negative Genetic
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein genetic 2 2 2 Synthetic Lethality, Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 2 2 2 Affinity Capture-RNA, Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 2 2 Co-purification, Affinity Capture-MS
TOP1 YOL006C Topoisomerase I genetic 2 2 2 Phenotypic Suppression, Phenotypic Enhancement
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes genetic 2 2 2 Synthetic Lethality, Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 2 2 Affinity Capture-RNA, Reconstituted Complex
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex genetic 2 2 2 Positive Genetic, Phenotypic Suppression
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 2 2 2 Synthetic Lethality, Negative Genetic
GBP2 YCL011C Poly(A+) RNA-binding protein physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
GBP2 YCL011C Poly(A+) RNA-binding protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 2 2 2 Synthetic Rescue, Negative Genetic
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 2 2 2 Synthetic Lethality, Positive Genetic
CDC73 YLR418C Component of the Paf1p complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 2 1 2 Negative Genetic, Negative Genetic
NOP4 YPL043W Nucleolar protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
CSL4 YNL232W Exosome non-catalytic core component genetic 2 1 2 Negative Genetic, Negative Genetic
THS1 YIL078W Threonyl-tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
URB1 YKL014C Protein required for the normal accumulation of 25S and 5.8S rRNAs physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UTP21 YLR409C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein genetic 2 1 2 Positive Genetic, Positive Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
THP1 YOL072W Nuclear pore-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SWC3 YAL011W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
TFB2 YPL122C Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 2 1 2 Negative Genetic, Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 2 1 2 Negative Genetic, Negative Genetic
SRC1 YML034W Inner nuclear membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 2 1 2 Positive Genetic, Positive Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 2 1 2 Positive Genetic, Positive Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 2 1 2 Negative Genetic, Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 2 1 2 Negative Genetic, Negative Genetic
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
RCL1 YOL010W Endonuclease that cleaves pre-rRNA at site A2 for 18S rRNA biogenesis physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARO1 YDR127W Pentafunctional arom protein genetic 2 1 2 Negative Genetic, Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 1 2 Positive Genetic, Positive Genetic
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 2 1 2 Negative Genetic, Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 2 Negative Genetic, Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 2 1 2 Negative Genetic, Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 2 Positive Genetic, Positive Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 2 Positive Genetic, Positive Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 2 1 2 Positive Genetic, Positive Genetic
PRP4 YPR178W Splicing factor genetic 2 1 2 Negative Genetic, Negative Genetic
PNO1 YOR145C Essential nucleolar protein required for pre-18S rRNA processing physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BUD13 YGL174W Subunit of the RES complex genetic 2 1 2 Positive Genetic, Positive Genetic
FUM1 YPL262W Fumarase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 2 1 2 Negative Genetic, Negative Genetic
NOP13 YNL175C Nucleolar protein found in preribosomal complexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 2 1 2 Negative Genetic, Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 2 1 2 Negative Genetic, Negative Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 2 1 2 Negative Genetic, Negative Genetic
HSP12 YFL014W Plasma membrane protein involved in maintaining membrane organization physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
RMD8 YFR048W Cytosolic protein required for sporulation genetic 2 1 2 Negative Genetic, Negative Genetic
NPL3 YDR432W RNA-binding protein physical 2 2 1 Affinity Capture-Western, Two-hybrid
LCB2 YDR062W Component of serine palmitoyltransferase genetic 2 2 1 Positive Genetic, Negative Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
HYP2 YEL034W Translation elongation factor eIF-5A genetic 2 2 1 Positive Genetic, Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 2 2 1 Positive Genetic, Negative Genetic
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 2 1 1 Negative Genetic, Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 2 1 1 Negative Genetic, Negative Genetic
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
ARR1 YPR199C Transcriptional activator of the basic leucine zipper (bZIP) family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CEF1 YMR213W Essential splicing factor genetic 1 1 1 Positive Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Positive Genetic
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 1 1 1 Negative Genetic
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase genetic 1 1 1 Positive Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Synthetic Growth Defect
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs genetic 1 1 1 Synthetic Rescue
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Positive Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Phenotypic Enhancement
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
BRX1 YOL077C Nucleolar protein physical 1 1 1 Affinity Capture-MS
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing genetic 1 1 1 Negative Genetic
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly physical 1 1 1 Affinity Capture-MS
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly genetic 1 1 1 Negative Genetic
ERB1 YMR049C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
HAS1 YMR290C ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
MAK16 YAL025C Essential nuclear protein physical 1 1 1 Affinity Capture-MS
MAK16 YAL025C Essential nuclear protein genetic 1 1 1 Negative Genetic
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase genetic 1 1 1 Negative Genetic
NOP16 YER002W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
NOP4 YPL043W Nucleolar protein genetic 1 1 1 Negative Genetic
NOP7 YGR103W Component of several different pre-ribosomal particles genetic 1 1 1 Negative Genetic
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit genetic 1 1 1 Negative Genetic
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
RPL17A YKL180W Ribosomal 60S subunit protein L17A physical 1 1 1 Affinity Capture-MS
RPL27A YHR010W Ribosomal 60S subunit protein L27A physical 1 1 1 Affinity Capture-MS
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins genetic 1 1 1 Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 1 1 1 Negative Genetic
KAP123 YER110C Karyopherin beta physical 1 1 1 Affinity Capture-MS
NUC1 YJL208C Major mitochondrial nuclease genetic 1 1 1 Negative Genetic
AXL2 YIL140W Integral plasma membrane protein genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Positive Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
POP4 YBR257W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
POP8 YBL018C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Positive Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 1 1 1 Affinity Capture-MS
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Negative Genetic
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes physical 1 1 1 Affinity Capture-MS
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 1 1 1 Affinity Capture-MS
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic physical 1 1 1 Affinity Capture-MS
RRP14 YKL082C Essential protein, constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
NAN1 YPL126W U3 snoRNP protein physical 1 1 1 Affinity Capture-MS
DIP2 YLR129W Nucleolar protein physical 1 1 1 Affinity Capture-MS
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger physical 1 1 1 Affinity Capture-MS
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-MS
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
NOP15 YNL110C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 Affinity Capture-MS
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases genetic 1 1 1 Positive Genetic
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Affinity Capture-MS
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Negative Genetic
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins genetic 1 1 1 Negative Genetic
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
MAK21 YDR060W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs genetic 1 1 1 Negative Genetic
PUS7 YOR243C Pseudouridine synthase genetic 1 1 1 Synthetic Rescue
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 1 1 1 Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Positive Genetic
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
RPC40 YPR110C RNA polymerase subunit AC40 genetic 1 1 1 Negative Genetic
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
RRP43 YCR035C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
RRP45 YDR280W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
RRP42 YDL111C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-Western
SXM1 YDR395W Nuclear transport factor (karyopherin) physical 1 1 1 Affinity Capture-MS
RSA4 YCR072C Ribosomal large subunit (60S) assembly factor physical 1 1 1 Affinity Capture-MS
RSM24 YDR175C Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
RTC1 YOL138C Subunit of SEACAT, a subcomplex of the SEA complex physical 1 1 1 Affinity Capture-MS
RTC3 YHR087W Protein of unknown function involved in RNA metabolism physical 1 1 1 Affinity Capture-MS
RTT109 YLL002W Histone acetyltransferase physical 1 1 1 Affinity Capture-MS
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
SAC6 YDR129C Fimbrin, actin-bundling protein physical 1 1 1 Affinity Capture-MS
SAH1 YER043C S-adenosyl-L-homocysteine hydrolase physical 1 1 1 Affinity Capture-MS
SAM2 YDR502C S-adenosylmethionine synthetase physical 1 1 1 Affinity Capture-MS
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
SCW10 YMR305C Cell wall protein with similarity to glucanases physical 1 1 1 Affinity Capture-MS
SEC53 YFL045C Phosphomannomutase physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
SER1 YOR184W 3-phosphoserine aminotransferase physical 1 1 1 Affinity Capture-MS
SES1 YDR023W Cytosolic seryl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
SFM1 YOR021C SPOUT methyltransferase physical 1 1 1 Affinity Capture-MS
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p physical 1 1 1 Affinity Capture-MS
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis physical 1 1 1 Affinity Capture-MS
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 1 1 1 Affinity Capture-MS
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Affinity Capture-MS
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase physical 1 1 1 Affinity Capture-MS
SPE3 YPR069C Spermidine synthase physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 1 1 1 Affinity Capture-MS
SSE2 YBR169C Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family physical 1 1 1 Affinity Capture-MS
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) physical 1 1 1 Affinity Capture-MS
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone physical 1 1 1 Affinity Capture-MS
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 1 1 1 Affinity Capture-MS
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export physical 1 1 1 Affinity Capture-MS
TAL1 YLR354C Transaldolase, enzyme in the non-oxidative pentose phosphate pathway physical 1 1 1 Affinity Capture-MS
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Affinity Capture-MS
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B physical 1 1 1 Affinity Capture-MS
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase physical 1 1 1 Affinity Capture-MS
THR4 YCR053W Threonine synthase physical 1 1 1 Affinity Capture-MS
TIF2 YJL138C Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
TIF1 YKR059W Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
TIF1 YKR059W Translation initiation factor eIF4A genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
TIR1 YER011W Cell wall mannoprotein physical 1 1 1 Affinity Capture-MS
TKL1 YPR074C Transketolase physical 1 1 1 Affinity Capture-MS
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
TMA19 YKL056C Protein that associates with ribosomes physical 1 1 1 Affinity Capture-MS
TMA20 YER007C-A Protein of unknown function that associates with ribosomes physical 1 1 1 Affinity Capture-MS
TPI1 YDR050C Triose phosphate isomerase, abundant glycolytic enzyme physical 1 1 1 Affinity Capture-MS
TPM1 YNL079C Major isoform of tropomyosin physical 1 1 1 Affinity Capture-MS
TRL1 YJL087C tRNA ligase physical 1 1 1 Affinity Capture-MS
TRP5 YGL026C Tryptophan synthase physical 1 1 1 Affinity Capture-MS
TRR1 YDR353W Cytoplasmic thioredoxin reductase physical 1 1 1 Affinity Capture-MS
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme physical 1 1 1 Affinity Capture-MS
TSA1 YML028W Thioredoxin peroxidase physical 1 1 1 Affinity Capture-MS
UBA1 YKL210W Ubiquitin activating enzyme (E1) physical 1 1 1 Affinity Capture-MS
UBC1 YDR177W Ubiquitin-conjugating enzyme physical 1 1 1 Affinity Capture-MS
UBI4 YLL039C Ubiquitin physical 1 1 1 Affinity Capture-MS
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) physical 1 1 1 Affinity Capture-MS
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) genetic 1 1 1 Negative Genetic
URA6 YKL024C Uridylate kinase physical 1 1 1 Affinity Capture-MS
URA6 YKL024C Uridylate kinase genetic 1 1 1 Negative Genetic
URB1 YKL014C Protein required for the normal accumulation of 25S and 5.8S rRNAs genetic 1 1 1 Positive Genetic
UTP21 YLR409C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Negative Genetic
VAS1 YGR094W Mitochondrial and cytoplasmic valyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VMA10 YHR039C-A Subunit G of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VMA4 YOR332W Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) physical 1 1 1 Affinity Capture-MS
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis physical 1 1 1 Affinity Capture-MS
WTM1 YOR230W Transcriptional modulator physical 1 1 1 Affinity Capture-MS
YBR085C-A YBR085C-A Protein of unknown function physical 1 1 1 Affinity Capture-MS
YDL086W YDL086W Putative carboxymethylenebutenolidase physical 1 1 1 Affinity Capture-MS
YDL124W YDL124W NADPH-dependent alpha-keto amide reductase physical 1 1 1 Affinity Capture-MS
YGL117W YGL117W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YGL138C YGL138C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YHB1 YGR234W Nitric oxide oxidoreductase physical 1 1 1 Affinity Capture-MS
YHR020W YHR020W Prolyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex physical 1 1 1 Affinity Capture-MS
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Positive Genetic
YLR179C YLR179C Protein of unknown function with similarity to Tfs1p physical 1 1 1 Affinity Capture-MS
YMR027W YMR027W A metal-dependent phosphatase, part of the DUF89 protein family physical 1 1 1 Affinity Capture-MS
YMR099C YMR099C Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) physical 1 1 1 Affinity Capture-MS
YMR295C YMR295C Protein of unknown function that associates with ribosomes physical 1 1 1 Affinity Capture-MS
YNK1 YKL067W Nucleoside diphosphate kinase physical 1 1 1 Affinity Capture-MS
YNL208W YNL208W Protein of unknown function physical 1 1 1 Affinity Capture-MS
YOR283W YOR283W Phosphatase with a broad substrate specificity physical 1 1 1 Affinity Capture-MS
YPL225W YPL225W Protein of unknown function physical 1 1 1 Affinity Capture-MS
YPR1 YDR368W NADPH-dependent aldo-keto reductase physical 1 1 1 Affinity Capture-MS
ZEO1 YOL109W Peripheral membrane protein of the plasma membrane physical 1 1 1 Affinity Capture-MS
TRX1 YLR043C Cytoplasmic thioredoxin isoenzyme physical 1 1 1 Affinity Capture-MS
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK physical 1 1 1 Affinity Capture-Western
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Synthetic Rescue
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 1 1 1 Affinity Capture-MS
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Affinity Capture-MS
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase physical 1 1 1 Affinity Capture-MS
UTP9 YHR196W Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 1 1 1 Affinity Capture-MS
RRP7 YCL031C Essential protein involved in rRNA processing and ribosome biogenesis physical 1 1 1 Affinity Capture-MS
RRP7 YCL031C Essential protein involved in rRNA processing and ribosome biogenesis genetic 1 1 1 Negative Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes physical 1 1 1 Affinity Capture-MS
UTP11 YKL099C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
UTP11 YKL099C Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Negative Genetic
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
UTP7 YER082C Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP7 YER082C Nucleolar protein genetic 1 1 1 Negative Genetic
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-MS
UTP20 YBL004W Component of the small-subunit (SSU) processome physical 1 1 1 Affinity Capture-MS
RRP9 YPR137W Protein involved in pre-rRNA processing physical 1 1 1 Affinity Capture-MS
UTP15 YMR093W Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Affinity Capture-MS
RRT14 YIL127C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
RRT14 YIL127C Putative protein of unknown function genetic 1 1 1 Negative Genetic
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation physical 1 1 1 Affinity Capture-MS
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation genetic 1 1 1 Synthetic Lethality
UTP5 YDR398W Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
TSR1 YDL060W Protein required for processing of 20S pre-rRNA in the cytoplasm physical 1 1 1 Affinity Capture-MS
UTP13 YLR222C Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus physical 1 1 1 Affinity Capture-MS
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
TFA2 YKR062W TFIIE small subunit genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Negative Genetic
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 1 1 1 Negative Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 1 1 1 Negative Genetic
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
TRM44 YPL030W tRNA(Ser) Um(44) 2'-O-methyltransferase genetic 1 1 1 Synthetic Rescue
TAN1 YGL232W Putative tRNA acetyltransferase genetic 1 1 1 Synthetic Rescue
TRM2 YKR056W tRNA methyltransferase genetic 1 1 1 Negative Genetic
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
SEN15 YMR059W Subunit of the tRNA splicing endonuclease genetic 1 1 1 Negative Genetic
WHI3 YNL197C RNA binding protein that modulates mRNA stability genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Positive Genetic
SQT1 YIR012W Specific assembly chaperone for ribosomal protein Rpl10p genetic 1 1 1 Positive Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Positive Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Negative Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 1 1 1 Synthetic Growth Defect
STD1 YOR047C Protein involved in control of glucose-regulated gene expression genetic 1 1 1 Negative Genetic
ZAP1 YJL056C Zinc-regulated transcription factor genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
YML119W YML119W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SPT23 YKL020C ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Positive Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Negative Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Negative Genetic
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Dosage Lethality
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Phenotypic Enhancement
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Positive Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Positive Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Positive Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Positive Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Positive Genetic
TAH11 YJR046W DNA replication licensing factor genetic 1 1 1 Positive Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Positive Genetic
TAF11 YML015C TFIID subunit (40 kDa) genetic 1 1 1 Positive Genetic
TFB5 YDR079C-A Component of RNA polymerase II general transcription factor TFIIH genetic 1 1 1 Positive Genetic
TMH11 YJR085C Mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Positive Genetic
SPO24 YPR036W-A Small (67 amino acids) protein involved in sporulation genetic 1 1 1 Positive Genetic
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Negative Genetic
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Negative Genetic
SCM3 YDL139C Nonhistone component of centromeric chromatin genetic 1 1 1 Negative Genetic
STN1 YDR082W Telomere end-binding and capping protein genetic 1 1 1 Negative Genetic
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
UTP6 YDR449C Nucleolar protein genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Negative Genetic
SDA1 YGR245C Protein required for actin organization and passage through Start genetic 1 1 1 Negative Genetic
URB2 YJR041C Protein required for normal metabolism of the rRNA primary transcript genetic 1 1 1 Negative Genetic
SWD2 YKL018W Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex genetic 1 1 1 Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 1 1 1 Negative Genetic
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
SEN54 YPL083C Subunit of the tRNA splicing endonuclease genetic 1 1 1 Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat genetic 1 1 1 Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 1 1 1 Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
SCS22 YBL091C-A Protein involved in regulation of phospholipid metabolism genetic 1 1 1 Negative Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Negative Genetic
SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
YIH1 YCR059C Negative regulator of eIF2 kinase Gcn2p genetic 1 1 1 Negative Genetic
YDL180W YDL180W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
SIP1 YDR422C One of three alternate beta-subunits of the Snf1p kinase complex genetic 1 1 1 Negative Genetic
TSA2 YDR453C Stress inducible cytoplasmic thioredoxin peroxidase genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
YEL025C YEL025C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YER079W YER079W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SBH1 YER087C-B Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) genetic 1 1 1 Negative Genetic
TRP2 YER090W Anthranilate synthase genetic 1 1 1 Negative Genetic
YER175W-A YER175W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGL114W YGL114W Putative protein of unknown function genetic 1 1 1 Negative Genetic
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
YGR111W YGR111W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YHL017W YHL017W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Phenotypic Suppression
YKL075C YKL075C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKL183C-A YKL183C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Negative Genetic
XDJ1 YLR090W Chaperone with a role in facilitating mitochondrial protein import genetic 1 1 1 Negative Genetic
YLR162W YLR162W Protein of unknown function genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
SKP2 YNL311C F-box protein of unknown function genetic 1 1 1 Negative Genetic
YOL164W-A YOL164W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Negative Genetic
YOR292C YOR292C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
YPL068C YPL068C Protein of unknown function genetic 1 1 1 Negative Genetic
YPL150W YPL150W Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
YPL191C YPL191C K48-specific deubiquitinating (DUB) enzyme genetic 1 1 1 Negative Genetic
TMH18 YPR098C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
SKI3 YPR189W Ski complex component and TPR protein genetic 1 1 1 Negative Genetic
SRP14 YDL092W Signal recognition particle (SRP) subunit genetic 1 1 1 Phenotypic Suppression
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Rescue
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Synthetic Lethality
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Negative Genetic
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Negative Genetic
RPA135 YPR010C RNA polymerase I second largest subunit A135 genetic 1 1 1 Synthetic Growth Defect
RPA43 YOR340C RNA polymerase I subunit A43 genetic 1 1 1 Positive Genetic
RRB1 YMR131C Specific assembly chaperone for ribosomal protein Rpl3p physical 1 1 1 Affinity Capture-MS
HPR1 YDR138W Subunit of THO/TREX complexes physical 1 1 1 Affinity Capture-Western
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase physical 1 1 1 Affinity Capture-MS
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Synthetic Rescue
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 1 1 1 Negative Genetic
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Affinity Capture-MS
RLI1 YDR091C Essential Fe-S protein physical 1 1 1 Affinity Capture-MS
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
PTA1 YAL043C Subunit of holo-CPF genetic 1 1 1 Negative Genetic
IMD2 YHR216W Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
PRE8 YML092C Alpha 2 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Growth Defect
PUF6 YDR496C Pumilio-homology domain protein physical 1 1 1 Affinity Capture-MS
PUS1 YPL212C tRNA:pseudouridine synthase physical 1 1 1 Affinity Capture-MS
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Affinity Capture-MS
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Negative Genetic
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 1 1 1 Phenotypic Enhancement
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA physical 1 1 1 Affinity Capture-MS
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA genetic 1 1 1 Synthetic Rescue
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF physical 1 1 1 Affinity Capture-MS
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme physical 1 1 1 Affinity Capture-MS
ADE13 YLR359W Adenylosuccinate lyase physical 1 1 1 Affinity Capture-MS
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Negative Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Positive Genetic
ARO1 YDR127W Pentafunctional arom protein physical 1 1 1 Affinity Capture-MS
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Affinity Capture-MS
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Synthetic Growth Defect
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Biochemical Activity
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Synthetic Growth Defect
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Phenotypic Suppression
NOG2 YNR053C Putative GTPase physical 1 1 1 Affinity Capture-MS
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Positive Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Negative Genetic
CYS4 YGR155W Cystathionine beta-synthase physical 1 1 1 Affinity Capture-MS
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
EMG1 YLR186W Methyltransferase for rRNA physical 1 1 1 Affinity Capture-MS
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs genetic 1 1 1 Negative Genetic
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase physical 1 1 1 Affinity Capture-MS
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Positive Genetic
FRS1 YLR060W Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
GCN2 YDR283C Protein kinase physical 1 1 1 Affinity Capture-MS
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
GDI1 YER136W GDP dissociation inhibitor physical 1 1 1 Affinity Capture-MS
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HST1 YOL068C NAD(+)-dependent histone deacetylase genetic 1 1 1 Negative Genetic
IRR1 YIL026C Subunit of the cohesin complex physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Phenotypic Enhancement
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 1 1 1 Affinity Capture-MS
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit genetic 1 1 1 Negative Genetic
MPP10 YJR002W Component of the SSU processome and 90S preribosome physical 1 1 1 Affinity Capture-MS
IMP3 YHR148W Component of the SSU processome physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Negative Genetic
KRS1 YDR037W Lysyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase genetic 1 1 1 Negative Genetic
DIB1 YPR082C 17-kDa component of the U4/U6aU5 tri-snRNP genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
LYS2 YBR115C Alpha aminoadipate reductase physical 1 1 1 Affinity Capture-MS
LYS2 YBR115C Alpha aminoadipate reductase genetic 1 1 1 Synthetic Rescue
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Negative Genetic
MBP1 YDL056W Transcription factor genetic 1 1 1 Negative Genetic
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) physical 1 1 1 Affinity Capture-MS
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair physical 1 1 1 Affinity Capture-MS
MLC1 YGL106W Essential light chain for Myo1p physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Phenotypic Enhancement
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins physical 1 1 1 Affinity Capture-MS
LYS12 YIL094C Homo-isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
FPR4 YLR449W Peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
FPR4 YLR449W Peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity physical 1 1 1 Affinity Capture-MS
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
PAP1 YKR002W Poly(A) polymerase physical 1 1 1 Affinity Capture-Western
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Negative Genetic
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Growth Defect
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
PRO2 YOR323C Gamma-glutamyl phosphate reductase physical 1 1 1 Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Positive Genetic
NUD1 YOR373W Mitotic exit network (MEN) scaffold protein physical 1 1 1 Affinity Capture-MS
PAA1 YDR071C Polyamine acetyltransferase physical 1 1 1 Affinity Capture-MS
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Synthetic Growth Defect
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
NAB6 YML117W Putative RNA-binding protein genetic 1 1 1 Dosage Rescue
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome physical 1 1 1 Affinity Capture-MS
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase physical 1 1 1 Affinity Capture-MS
NOP14 YDL148C Nucleolar protein physical 1 1 1 Affinity Capture-MS
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
NOC4 YPR144C Nucleolar protein physical 1 1 1 Affinity Capture-MS
NOC4 YPR144C Nucleolar protein genetic 1 1 1 Positive Genetic
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Negative Genetic
RAD3 YER171W 5' to 3' DNA helicase genetic 1 1 1 Synthetic Rescue
RAD51 YER095W Strand exchange protein genetic 1 1 1 Phenotypic Suppression
RAI1 YGL246C Nuclear decapping endonuclease genetic 1 1 1 Synthetic Lethality
REF2 YDR195W RNA-binding protein genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Phenotypic Suppression
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Positive Genetic
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes genetic 1 1 1 Negative Genetic
FYV8 YGR196C Protein of unknown function genetic 1 1 1 Negative Genetic
RNH1 YMR234W Ribonuclease H1 genetic 1 1 1 Phenotypic Suppression
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NUT2 YPR168W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
RPL23A YBL087C Ribosomal 60S subunit protein L23A physical 1 1 1 Affinity Capture-MS
ADE3 YGR204W Cytoplasmic trifunctional enzyme physical 1 1 1 Affinity Capture-MS
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Synthetic Lethality
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 1 1 1 Negative Genetic
RPO26 YPR187W RNA polymerase subunit ABC23 genetic 1 1 1 Synthetic Rescue
MTR3 YGR158C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase physical 1 1 1 Affinity Capture-MS
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor physical 1 1 1 Affinity Capture-MS
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 1 1 1 Positive Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Negative Genetic
ABF2 YMR072W Mitochondrial DNA-binding protein physical 1 1 1 Affinity Capture-MS
BGL2 YGR282C Endo-beta-1,3-glucanase physical 1 1 1 Affinity Capture-MS
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Positive Genetic
PRP42 YDR235W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Phenotypic Enhancement
CRN1 YLR429W Coronin physical 1 1 1 Affinity Capture-MS
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
CAM1 YPL048W One of two isoforms of the gamma subunit of eEF1B physical 1 1 1 Affinity Capture-MS
EFB1 YAL003W Translation elongation factor 1 beta physical 1 1 1 Affinity Capture-MS
EFB1 YAL003W Translation elongation factor 1 beta genetic 1 1 1 Negative Genetic
GLN1 YPR035W Glutamine synthetase (GS) physical 1 1 1 Affinity Capture-MS
FDH1 YOR388C NAD(+)-dependent formate dehydrogenase genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 1 1 1 Affinity Capture-MS
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) genetic 1 1 1 Negative Genetic
LTV1 YKL143W Subunit of the EGO/GSE complex physical 1 1 1 Affinity Capture-MS
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 1 1 1 Affinity Capture-MS
DTD1 YDL219W D-Tyr-tRNA(Tyr) deacylase physical 1 1 1 Affinity Capture-MS
LYS9 YNR050C Saccharopine dehydrogenase (NADP+, L-glutamate-forming) physical 1 1 1 Affinity Capture-MS
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton physical 1 1 1 Affinity Capture-MS
CAR2 YLR438W L-ornithine transaminase (OTAse) physical 1 1 1 Affinity Capture-MS
PYC2 YBR218C Pyruvate carboxylase isoform physical 1 1 1 Affinity Capture-MS
ACH1 YBL015W Protein with CoA transferase activity genetic 1 1 1 Positive Genetic
HYP2 YEL034W Translation elongation factor eIF-5A physical 1 1 1 Affinity Capture-MS
ADO1 YJR105W Adenosine kinase physical 1 1 1 Affinity Capture-MS
PPQ1 YPL179W Protein phosphatase that regulates the mating response physical 1 1 1 Affinity Capture-MS
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase physical 1 1 1 Affinity Capture-MS
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity physical 1 1 1 Affinity Capture-MS
NMD5 YJR132W Karyopherin genetic 1 1 1 Positive Genetic
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange physical 1 1 1 Affinity Capture-MS
AHP1 YLR109W Thiol-specific peroxiredoxin physical 1 1 1 Affinity Capture-MS
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Negative Genetic
DPS1 YLL018C Aspartyl-tRNA synthetase, primarily cytoplasmic physical 1 1 1 Affinity Capture-MS
GRR1 YJR090C F-box protein component of an SCF ubiquitin-ligase complex physical 1 1 1 Affinity Capture-MS
ARO4 YBR249C 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase physical 1 1 1 Affinity Capture-MS
OYE2 YHR179W Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) physical 1 1 1 Affinity Capture-MS
KOG1 YHR186C Subunit of TORC1 genetic 1 1 1 Positive Genetic
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 1 1 1 Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Positive Genetic
LCP5 YER127W Essential protein involved in maturation of 18S rRNA genetic 1 1 1 Positive Genetic
ADK1 YDR226W Adenylate kinase, required for purine metabolism physical 1 1 1 Affinity Capture-MS
PGM2 YMR105C Phosphoglucomutase physical 1 1 1 Affinity Capture-MS
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization physical 1 1 1 Affinity Capture-MS
LIA1 YJR070C Deoxyhypusine hydroxylase physical 1 1 1 Affinity Capture-MS
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
PRO3 YER023W Delta 1-pyrroline-5-carboxylate reductase physical 1 1 1 Affinity Capture-MS
DLD3 YEL071W 2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase physical 1 1 1 Affinity Capture-MS
ACS2 YLR153C Acetyl-coA synthetase isoform physical 1 1 1 Affinity Capture-MS
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 1 1 1 Negative Genetic
ILV3 YJR016C Dihydroxyacid dehydratase physical 1 1 1 Affinity Capture-MS
ERG10 YPL028W Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) physical 1 1 1 Affinity Capture-MS
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
GUF1 YLR289W Mitochondrial matrix GTPase physical 1 1 1 Affinity Capture-MS
IMD4 YML056C Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription physical 1 1 1 Affinity Capture-MS
CDC60 YPL160W Cytosolic leucyl tRNA synthetase physical 1 1 1 Affinity Capture-MS
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 1 1 1 Positive Genetic
ERG20 YJL167W Farnesyl pyrophosphate synthetase physical 1 1 1 Affinity Capture-MS
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 1 1 1 Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone physical 1 1 1 Affinity Capture-MS
GPN3 YLR243W Putative GTPase with a role in biogenesis of RNA pol II and polIII genetic 1 1 1 Positive Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) physical 1 1 1 Affinity Capture-MS
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
GRX1 YCL035C Glutathione-dependent disulfide oxidoreductase physical 1 1 1 Affinity Capture-MS
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Negative Genetic
ARE1 YCR048W Acyl-CoA:sterol acyltransferase genetic 1 1 1 Negative Genetic
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis physical 1 1 1 Affinity Capture-MS
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis genetic 1 1 1 Positive Genetic
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 genetic 1 1 1 Negative Genetic
KEL2 YGR238C Protein that negatively regulates mitotic exit genetic 1 1 1 Negative Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 1 1 1 Negative Genetic
EMI2 YDR516C Hexokinase expressed during growth with low glucose levels physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen physical 1 1 1 Affinity Capture-MS
RCN2 YOR220W Protein of unknown function physical 1 1 1 Affinity Capture-MS
ATG4 YNL223W Conserved cysteine protease required for autophagy genetic 1 1 1 Negative Genetic
ARF2 YDL137W ADP-ribosylation factor genetic 1 1 1 Negative Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake physical 1 1 1 Affinity Capture-MS
MAP2 YBL091C Methionine aminopeptidase physical 1 1 1 Affinity Capture-MS
PAP2 YOL115W Non-canonical poly(A) polymerase physical 1 1 1 Reconstituted Complex
AIR1 YIL079C Zinc knuckle protein genetic 1 1 1 Phenotypic Enhancement
APA1 YCL050C AP4A phosphorylase physical 1 1 1 Affinity Capture-MS
CIA1 YDR267C Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
CPR3 YML078W Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
LOS1 YKL205W Nuclear pore protein genetic 1 1 1 Dosage Rescue
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Proximity Label-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Negative Genetic
FCF1 YDR339C PINc domain endonuclease genetic 1 1 1 Negative Genetic
RAD26 YJR035W Protein involved in transcription-coupled nucleotide excision repair genetic 1 1 1 Synthetic Growth Defect
ADH6 YMR318C NADPH-dependent medium chain alcohol dehydrogenase physical 1 1 1 Affinity Capture-MS
PMI40 YER003C Mannose-6-phosphate isomerase physical 1 1 1 Affinity Capture-MS
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
CYS3 YAL012W Cystathionine gamma-lyase physical 1 1 1 Affinity Capture-MS
MDH3 YDL078C Peroxisomal malate dehydrogenase physical 1 1 1 Affinity Capture-MS
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
REX2 YLR059C 3'-5' RNA exonuclease genetic 1 1 1 Dosage Rescue
RPL5 YPL131W Ribosomal 60S subunit protein L5 genetic 1 1 1 Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Synthetic Rescue
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 physical 1 1 1 Affinity Capture-MS
GDH1 YOR375C NADP(+)-dependent glutamate dehydrogenase physical 1 1 1 Affinity Capture-MS
ACO2 YJL200C Putative mitochondrial aconitase isozyme physical 1 1 1 Affinity Capture-MS
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Phenotypic Enhancement
KAR4 YCL055W Transcription factor required for response to pheromones genetic 1 1 1 Negative Genetic
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) physical 1 1 1 Affinity Capture-MS
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
MRP8 YKL142W Protein of unknown function physical 1 1 1 Affinity Capture-MS
NIF3 YGL221C Protein of unknown function physical 1 1 1 Affinity Capture-MS
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Positive Genetic
PEX18 YHR160C Peroxin genetic 1 1 1 Negative Genetic
PCL8 YPL219W Cyclin genetic 1 1 1 Negative Genetic
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) physical 1 1 1 Affinity Capture-MS
RPS26A YGL189C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
ATG34 YOL083W Receptor protein involved in selective autophagy during starvation physical 1 1 1 Affinity Capture-MS
RMD1 YDL001W Cytoplasmic protein required for sporulation genetic 1 1 1 Negative Genetic
PET191 YJR034W Protein required for assembly of cytochrome c oxidase genetic 1 1 1 Negative Genetic
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Positive Genetic
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site genetic 1 1 1 Negative Genetic
AKR2 YOR034C Ankyrin repeat-containing protein genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Positive Genetic
RIB4 YOL143C Lumazine synthase (DMRL synthase) physical 1 1 1 Affinity Capture-MS
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
NNF1 YJR112W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis physical 1 1 1 Affinity Capture-MS
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Negative Genetic
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
CRP1 YHR146W Protein that binds to cruciform DNA structures physical 1 1 1 Affinity Capture-MS
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Negative Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 1 1 1 Negative Genetic
IES6 YEL044W Component of the INO80 chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
MRS1 YIR021W Splicing protein genetic 1 1 1 Negative Genetic
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
ALF1 YNL148C Alpha-tubulin folding protein physical 1 1 1 Affinity Capture-MS
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex physical 1 1 1 Affinity Capture-MS
EPS1 YIL005W ER protein with chaperone and co-chaperone activity physical 1 1 1 Affinity Capture-MS
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease physical 1 1 1 Affinity Capture-MS
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease genetic 1 1 1 Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
HNT1 YDL125C Adenosine 5'-monophosphoramidase physical 1 1 1 Affinity Capture-MS
HOP1 YIL072W Meiosis-specific protein required for chromosome synapsis physical 1 1 1 Affinity Capture-MS
HOP1 YIL072W Meiosis-specific protein required for chromosome synapsis genetic 1 1 1 Negative Genetic
HSP150 YJL159W O-mannosylated heat shock protein physical 1 1 1 Affinity Capture-MS
HSP150 YJL159W O-mannosylated heat shock protein genetic 1 1 1 Dosage Rescue
HXK2 YGL253W Hexokinase isoenzyme 2 physical 1 1 1 Affinity Capture-MS
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export physical 1 1 1 Affinity Capture-Western
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway physical 1 1 1 Affinity Capture-MS
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Negative Genetic
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA physical 1 1 1 Affinity Capture-MS
BET1 YIL004C Type II membrane protein required for vesicular transport genetic 1 1 1 Negative Genetic
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Phenotypic Enhancement
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation physical 1 1 1 Affinity Capture-MS
HRB1 YNL004W Poly(A+) RNA-binding protein physical 1 1 1 Affinity Capture-Western
HRB1 YNL004W Poly(A+) RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
JNM1 YMR294W Component of the yeast dynactin complex physical 1 1 1 Affinity Capture-MS
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding genetic 1 1 1 Negative Genetic
PHO2 YDL106C Homeobox transcription factor genetic 1 1 1 Positive Genetic
EMP46 YLR080W Integral membrane component of ER-derived COPII-coated vesicles physical 1 1 1 Affinity Capture-MS
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Negative Genetic
MBF1 YOR298C-A Transcriptional coactivator physical 1 1 1 Affinity Capture-MS
MBF1 YOR298C-A Transcriptional coactivator genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
GAL80 YML051W Transcriptional regulator involved in the repression of GAL genes genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis physical 1 1 1 Affinity Capture-MS
ARG80 YMR042W Transcription factor involved in regulating arginine-responsive genes genetic 1 1 1 Positive Genetic
CAT8 YMR280C Zinc cluster transcriptional activator genetic 1 1 1 Negative Genetic
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator genetic 1 1 1 Negative Genetic
HFM1 YGL251C Meiosis specific DNA helicase genetic 1 1 1 Positive Genetic
BPT1 YLL015W ABC type transmembrane transporter of MRP/CFTR family genetic 1 1 1 Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
GFD2 YCL036W Protein of unknown function genetic 1 1 1 Negative Genetic
HRI1 YLR301W Protein of unknown function that interacts with Sec72p and Hrr25p physical 1 1 1 Affinity Capture-MS
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
BAT2 YJR148W Cytosolic branched-chain amino acid (BCAA) aminotransferase physical 1 1 1 Affinity Capture-MS
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Phenotypic Suppression
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin physical 1 1 1 Affinity Capture-MS
HMS1 YOR032C bHLH protein with similarity to myc-family transcription factors genetic 1 1 1 Negative Genetic
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
OAF1 YAL051W Oleate-activated transcription factor genetic 1 1 1 Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Positive Genetic
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Negative Genetic
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 genetic 1 1 1 Negative Genetic
PBI2 YNL015W Cytosolic inhibitor of vacuolar proteinase B (PRB1) physical 1 1 1 Affinity Capture-MS
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
CAP2 YIL034C Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 1 1 1 Negative Genetic
ETT1 YOR051C Nuclear protein that inhibits replication of Brome mosaic virus physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Positive Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Negative Genetic
DBP6 YNR038W Essential protein involved in ribosome biogenesis genetic 1 1 1 Negative Genetic
DYS1 YHR068W Deoxyhypusine synthase physical 1 1 1 Affinity Capture-MS
ATM1 YMR301C Mitochondrial inner membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit physical 1 1 1 Affinity Capture-MS
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Positive Genetic
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response genetic 1 1 1 Negative Genetic
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Negative Genetic
NOP8 YOL144W Nucleolar protein required for 60S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-Western
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 physical 1 1 1 Affinity Capture-MS
GDH3 YAL062W NADP(+)-dependent glutamate dehydrogenase physical 1 1 1 Affinity Capture-MS
MLS1 YNL117W Malate synthase, enzyme of the glyoxylate cycle physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
ASN2 YGR124W Asparagine synthetase physical 1 1 1 Affinity Capture-MS
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
CRG1 YHR209W S-AdoMet-dependent methyltransferase involved in lipid homeostasis genetic 1 1 1 Synthetic Growth Defect
ARO8 YGL202W Aromatic aminotransferase I physical 1 1 1 Affinity Capture-MS
ARO80 YDR421W Zinc finger transcriptional activator of the Zn2Cys6 family genetic 1 1 1 Negative Genetic
FUR1 YHR128W Uracil phosphoribosyltransferase physical 1 1 1 Affinity Capture-MS
RPL16B YNL069C Ribosomal 60S subunit protein L16B physical 1 1 1 Affinity Capture-MS
GLR1 YPL091W Cytosolic and mitochondrial glutathione oxidoreductase physical 1 1 1 Affinity Capture-MS
PLP1 YDR183W Protein that interacts with CCT (chaperonin containing TCP-1) complex genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p physical 1 1 1 Affinity Capture-MS
CUE4 YML101C Protein of unknown function physical 1 1 1 Affinity Capture-MS
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
DUS3 YLR401C Dihydrouridine synthase genetic 1 1 1 Synthetic Rescue
MEI5 YPL121C Meiosis-specific protein involved in meiotic recombination physical 1 1 1 Affinity Capture-MS
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Positive Genetic
RMI1 YPL024W Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex genetic 1 1 1 Negative Genetic
BSC6 YOL137W Protein of unknown function with 8 putative transmembrane segments genetic 1 1 1 Negative Genetic
HAM1 YJR069C Nucleoside triphosphate pyrophosphohydrolase physical 1 1 1 Affinity Capture-MS
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein genetic 1 1 1 Negative Genetic
RPS31 YLR167W Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin physical 1 1 1 Affinity Capture-MS
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
GLK1 YCL040W Glucokinase physical 1 1 1 Affinity Capture-MS
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Negative Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Negative Genetic
ARI1 YGL157W NADPH-dependent aldehyde reductase physical 1 1 1 Affinity Capture-MS
HXK1 YFR053C Hexokinase isoenzyme 1 physical 1 1 1 Affinity Capture-MS
HXK1 YFR053C Hexokinase isoenzyme 1 genetic 1 1 1 Negative Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
LYS4 YDR234W Homoaconitase physical 1 1 1 Affinity Capture-MS
FCF2 YLR051C Nucleolar protein involved in the early steps of 35S rRNA processing genetic 1 1 1 Negative Genetic
PUF4 YGL014W Member of the PUF protein family genetic 1 1 1 Negative Genetic
FPR2 YDR519W Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
GUK1 YDR454C Guanylate kinase physical 1 1 1 Affinity Capture-MS
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
BNA1 YJR025C 3-hydroxyanthranilic acid dioxygenase physical 1 1 1 Affinity Capture-MS
CRS1 YNL247W Cysteinyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
CAB4 YGR277C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Negative Genetic
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Positive Genetic
RRP15 YPR143W Nucleolar protein genetic 1 1 1 Negative Genetic
GRE3 YHR104W Aldose reductase physical 1 1 1 Affinity Capture-MS
HOB2 YPR117W Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
PPN1 YDR452W Dual endo- and exopolyphosphatase with a role in phosphate metabolism physical 1 1 1 Affinity Capture-MS
ALD6 YPL061W Cytosolic aldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
KIN4 YOR233W Serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
CBS1 YDL069C Mitochondrial translational activator of the COB mRNA genetic 1 1 1 Negative Genetic
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 1 1 1 Negative Genetic
FRD1 YEL047C Soluble fumarate reductase physical 1 1 1 Affinity Capture-MS
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase physical 1 1 1 Affinity Capture-MS
NPT1 YOR209C Nicotinate phosphoribosyltransferase physical 1 1 1 Affinity Capture-MS
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 1 1 1 Negative Genetic
ROX1 YPR065W Heme-dependent repressor of hypoxic genes genetic 1 1 1 Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
HEM12 YDR047W Uroporphyrinogen decarboxylase genetic 1 1 1 Negative Genetic
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PSA1 YDL055C GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) physical 1 1 1 Affinity Capture-MS
PSA1 YDL055C GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) genetic 1 1 1 Dosage Rescue
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex physical 1 1 1 Affinity Capture-MS
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MIL1 YFL034W Predicted lipase genetic 1 1 1 Negative Genetic
RPP2A YOL039W Ribosomal protein P2 alpha physical 1 1 1 Affinity Capture-MS
GUA1 YMR217W GMP synthase physical 1 1 1 Affinity Capture-MS
LDB7 YBL006C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
NMT1 YLR195C N-myristoyl transferase physical 1 1 1 Affinity Capture-MS
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
HST4 YDR191W NAD(+)-dependent protein deacetylase genetic 1 1 1 Phenotypic Enhancement
PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p genetic 1 1 1 Positive Genetic
MIC26 YGR235C Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A physical 1 1 1 Affinity Capture-MS
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
OSH6 YKR003W Oxysterol-binding phosphatidylserine transferase genetic 1 1 1 Negative Genetic
MRX18 YBR056W Putative glycoside hydrolase of the mitochondrial intermembrane space physical 1 1 1 Affinity Capture-MS
HEM2 YGL040C Aminolevulinate dehydratase physical 1 1 1 Affinity Capture-MS
RIB3 YDR487C 3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase) physical 1 1 1 Affinity Capture-MS
PNC1 YGL037C Nicotinamidase that converts nicotinamide to nicotinic acid physical 1 1 1 Affinity Capture-MS
EEB1 YPL095C Acyl-coenzymeA:ethanol O-acyltransferase genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
ARF3 YOR094W Glucose-repressible ADP-ribosylation factor physical 1 1 1 Affinity Capture-MS
MRL1 YPR079W Membrane protein genetic 1 1 1 Negative Genetic
RRP17 YDR412W 5' exoribonuclease required for 5' end processing of pre-60S rRNA physical 1 1 1 Affinity Capture-MS
ADK2 YER170W Mitochondrial adenylate kinase genetic 1 1 1 Negative Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Negative Genetic
HPT1 YDR399W Dimeric hypoxanthine-guanine phosphoribosyltransferase physical 1 1 1 Affinity Capture-MS
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Positive Genetic
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase physical 1 1 1 Affinity Capture-MS
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase physical 1 1 1 Affinity Capture-MS
HSP32 YPL280W Possible chaperone and cysteine protease genetic 1 1 1 Negative Genetic
GRX2 YDR513W Cytoplasmic glutaredoxin physical 1 1 1 Affinity Capture-MS
FIT2 YOR382W Mannoprotein that is incorporated into the cell wall genetic 1 1 1 Negative Genetic
BSC4 YNL269W Protein of unknown function genetic 1 1 1 Negative Genetic
AVT5 YBL089W Putative transporter genetic 1 1 1 Negative Genetic
LCB4 YOR171C Sphingoid long-chain base kinase genetic 1 1 1 Negative Genetic
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase physical 1 1 1 Affinity Capture-MS
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Negative Genetic
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Positive Genetic
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
REX4 YOL080C Putative RNA exonuclease genetic 1 1 1 Negative Genetic
GRE2 YOL151W 3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase physical 1 1 1 Affinity Capture-MS
HTS1 YPR033C Cytoplasmic and mitochondrial histidine tRNA synthetase physical 1 1 1 Affinity Capture-MS
PRD1 YCL057W Zinc metalloendopeptidase physical 1 1 1 Affinity Capture-MS
GRX6 YDL010W Cis-Golgi localized monothiol glutaredoxin, binds Fe-S cluster genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
MAL31 YBR298C Maltose permease genetic 1 1 1 Negative Genetic
CMC2 YBL059C-A Protein involved in respiratory chain complex assembly or maintenance physical 1 1 1 Affinity Capture-MS
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B physical 1 1 1 Affinity Capture-MS
GPI1 YGR216C Membrane protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder genetic 1 1 1 Dosage Growth Defect
CTS2 YDR371W Putative chitinase physical 1 1 1 Affinity Capture-MS
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
IDP2 YLR174W Cytosolic NADP-specific isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Negative Genetic
REX3 YLR107W RNA exonuclease genetic 1 1 1 Dosage Rescue
FMT1 YBL013W Methionyl-tRNA formyltransferase genetic 1 1 1 Positive Genetic
ADF1 YCL058W-A Transcriptional repressor encoded by the FYV5 antisense strand genetic 1 1 1 Negative Genetic
MND1 YGL183C Protein required for recombination and meiotic nuclear division physical 1 1 1 Affinity Capture-MS
PES4 YFR023W Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation genetic 1 1 1 Negative Genetic
PZF1 YPR186C Transcription factor IIIA (TFIIIA) genetic 1 1 1 Negative Genetic
MTC6 YHR151C Protein of unknown function genetic 1 1 1 Negative Genetic
PAU14 YIL176C Protein of unknown function genetic 1 1 1 Negative Genetic