Standard name Systematic name Name description Description
SWC5 YBR231C Component of the SWR1 complex Component of the SWR1 complex; complex exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; protein abundance increases in response to DNA replication stress; relocalizes to the cytosol in response to hypoxia
Visualize the interactome of SWC5
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.057 0.383 NaN
Nucleolus 0.234 NaN NaN
Nucleus 0.905 0.861 0.939

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SWC5 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SWR1 YDR334W Swi2/Snf2-related ATPase physical 16 4 15 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS
BRE1 YDL074C E3 ubiquitin ligase genetic 8 3 7 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 8 3 7 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 8 3 7 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 8 3 6 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 7 3 7 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 7 3 7 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Lethality, Negative Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 7 3 6 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 7 3 6 Positive Genetic, Positive Genetic, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Positive Genetic, Positive Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 7 3 6 Synthetic Lethality, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 7 3 6 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 7 3 6 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 7 3 6 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 7 2 6 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic
CDC73 YLR418C Component of the Paf1p complex genetic 7 3 5 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 6 3 6 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 6 2 6 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 6 2 6 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 6 4 5 Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 6 3 5 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 6 3 5 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 6 3 5 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect, Negative Genetic
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding genetic 6 3 5 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 6 4 4 Negative Genetic, Phenotypic Enhancement, Positive Genetic, Synthetic Lethality, Synthetic Lethality, Positive Genetic
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 6 3 4 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 5 4 5 Synthetic Lethality, Negative Genetic, Positive Genetic, Synthetic Growth Defect, Positive Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 5 3 5 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 5 3 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 5 3 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 5 2 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 5 2 5 Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 5 2 5 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 5 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 5 2 5 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 5 2 5 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 5 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
HCM1 YCR065W Forkhead transcription factor genetic 5 2 5 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 5 3 4 Synthetic Lethality, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
BRE5 YNR051C Ubiquitin protease cofactor genetic 5 3 4 Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 5 2 4 Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 5 2 4 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
SWC3 YAL011W Protein of unknown function genetic 5 2 4 Positive Genetic, Positive Genetic, Phenotypic Suppression, Phenotypic Suppression, Positive Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 4 3 4 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 4 3 4 Negative Genetic, Positive Genetic, Synthetic Growth Defect, Positive Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 4 3 4 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 4 3 4 Synthetic Lethality, Negative Genetic, Positive Genetic, Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 4 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 4 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 4 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 4 2 4 Positive Genetic, Positive Genetic, Positive Genetic, Phenotypic Suppression
POL32 YJR043C Third subunit of DNA polymerase delta genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
SRC1 YML034W Inner nuclear membrane protein genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 4 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 4 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 4 3 3 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 4 2 3 Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 4 2 3 Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 4 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic
MSC1 YML128C Protein of unknown function genetic 4 2 3 Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 4 3 2 Phenotypic Enhancement, Phenotypic Enhancement, Positive Genetic, Negative Genetic
SAC3 YDR159W mRNA export factor genetic 3 3 3 Negative Genetic, Synthetic Growth Defect, Positive Genetic
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 3 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 3 2 3 Positive Genetic, Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 3 2 3 Phenotypic Enhancement, Negative Genetic, Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BDF1 YLR399C BET family transcriptional regulator physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
TUB3 YML124C Alpha-tubulin genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YPL150W YPL150W Protein kinase of unknown cellular role genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 3 1 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Positive Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Positive Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 3 2 2 Negative Genetic, Synthetic Rescue, Synthetic Rescue
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 3 2 2 Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
TED1 YIL039W GPI-glycan remodelase genetic 3 2 2 Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement
USO1 YDL058W Essential protein involved in vesicle-mediated ER to Golgi transport genetic 3 2 2 Negative Genetic, Negative Genetic, Positive Genetic
PHO80 YOL001W Cyclin genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Positive Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 3 2 2 Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 2 2 2 Positive Genetic, Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 2 2 2 Synthetic Lethality, Negative Genetic
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
THP1 YOL072W Nuclear pore-associated protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 2 2 2 Positive Genetic, Negative Genetic
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 2 2 2 Negative Genetic, Synthetic Lethality
SEC59 YMR013C Dolichol kinase genetic 2 2 2 Positive Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 2 1 2 Negative Genetic, Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 2 1 2 Negative Genetic, Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 2 1 2 Negative Genetic, Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 2 1 2 Negative Genetic, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
RPC19 YNL113W RNA polymerase subunit AC19 genetic 2 1 2 Negative Genetic, Negative Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 2 1 2 Negative Genetic, Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 2 1 2 Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 2 Negative Genetic, Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 2 1 2 Negative Genetic, Negative Genetic
BDF2 YDL070W Protein involved in transcription initiation genetic 2 1 2 Negative Genetic, Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 2 1 2 Negative Genetic, Negative Genetic
ADA2 YDR448W Transcription coactivator genetic 2 1 2 Negative Genetic, Negative Genetic
HTZ1 YOL012C Histone variant H2AZ physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins genetic 2 1 2 Negative Genetic, Negative Genetic
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity genetic 2 1 2 Negative Genetic, Negative Genetic
PRP28 YDR243C Pre-mRNA splicing factor genetic 2 1 2 Negative Genetic, Negative Genetic
PRP4 YPR178W Splicing factor genetic 2 1 2 Negative Genetic, Negative Genetic
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex genetic 2 1 2 Positive Genetic, Positive Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 2 1 2 Negative Genetic, Negative Genetic
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 2 1 2 Negative Genetic, Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 2 1 2 Negative Genetic, Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 2 1 2 Positive Genetic, Positive Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 2 1 2 Negative Genetic, Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 2 1 2 Negative Genetic, Negative Genetic
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking genetic 2 1 2 Negative Genetic, Negative Genetic
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 2 Negative Genetic, Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 2 1 2 Negative Genetic, Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 2 1 2 Negative Genetic, Negative Genetic
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 2 1 2 Negative Genetic, Negative Genetic
BUD13 YGL174W Subunit of the RES complex genetic 2 1 2 Negative Genetic, Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 2 1 2 Negative Genetic, Negative Genetic
KAP122 YGL016W Karyopherin beta genetic 2 1 2 Negative Genetic, Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 2 1 2 Negative Genetic, Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 2 1 2 Negative Genetic, Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 2 1 2 Negative Genetic, Negative Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 2 Positive Genetic, Positive Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 2 Negative Genetic, Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 2 1 2 Negative Genetic, Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 2 1 2 Negative Genetic, Negative Genetic
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 2 1 2 Negative Genetic, Negative Genetic
SWC7 YLR385C Protein of unknown function physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
VPS72 YDR485C Htz1p-binding component of the SWR1 complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 2 Negative Genetic, Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 2 1 2 Negative Genetic, Negative Genetic
TFB2 YPL122C Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
YPT31 YER031C Rab family GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 2 1 2 Negative Genetic, Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 2 1 2 Negative Genetic, Negative Genetic
YDR169C-A YDR169C-A Putative protein of unknown function genetic 2 1 2 Positive Genetic, Positive Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 2 1 2 Positive Genetic, Positive Genetic
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 2 1 2 Negative Genetic, Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 2 1 2 Negative Genetic, Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 1 2 Negative Genetic, Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 2 1 2 Negative Genetic, Negative Genetic
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 2 1 2 Negative Genetic, Negative Genetic
SWC3 YAL011W Protein of unknown function physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ENV11 YGR071C Protein proposed to be involved in vacuolar functions genetic 2 1 2 Negative Genetic, Negative Genetic
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 2 1 2 Negative Genetic, Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 2 1 2 Negative Genetic, Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 2 1 2 Negative Genetic, Negative Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 2 1 2 Negative Genetic, Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 2 1 2 Negative Genetic, Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 2 1 2 Negative Genetic, Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 2 1 2 Negative Genetic, Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
CYC1 YJR048W Cytochrome c, isoform 1 genetic 2 1 2 Negative Genetic, Negative Genetic
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 2 1 2 Negative Genetic, Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 2 1 2 Positive Genetic, Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 2 1 2 Negative Genetic, Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 2 1 2 Negative Genetic, Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 2 1 2 Negative Genetic, Negative Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 2 1 2 Negative Genetic, Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 2 1 2 Negative Genetic, Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 2 1 2 Positive Genetic, Positive Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 2 2 1 Negative Genetic, Positive Genetic
TAF3 YPL011C TFIID subunit (47 kDa) genetic 2 2 1 Positive Genetic, Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 2 2 1 Negative Genetic, Positive Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 2 2 1 Positive Genetic, Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
ERP1 YAR002C-A Member of the p24 family involved in ER to Golgi transport genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ERP2 YAL007C Member of the p24 family involved in ER to Golgi transport genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ARF1 YDL192W ADP-ribosylation factor genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BOP2 YLR267W Protein of unknown function genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
TFC1 YBR123C Subunit of RNA polymerase III transcription initiation factor complex physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
YHR078W YHR078W High osmolarity-regulated gene of unknown function genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
VPS3 YDR495C Component of CORVET membrane tethering complex genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
OST5 YGL226C-A Zeta subunit of the oligosaccharyltransferase complex of the ER lumen genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SIL1 YOL031C Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ERV14 YGL054C COPII-coated vesicle protein genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SSH1 YBR283C Subunit of the Ssh1 translocon complex genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
CWH41 YGL027C Processing alpha glucosidase I genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
RUD3 YOR216C Golgi matrix protein genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
GOT1 YMR292W Homodimeric protein that is packaged into COPII vesicles genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ITR1 YDR497C Myo-inositol transporter genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
CCW12 YLR110C Cell wall mannoprotein genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
EMP65 YER140W Integral membrane protein of the ER genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SLP1 YOR154W Glycosylated integral ER membrane protein of unknown function genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Negative Genetic
CDC40 YDR364C Pre-mRNA splicing factor genetic 1 1 1 Negative Genetic
CEF1 YMR213W Essential splicing factor genetic 1 1 1 Negative Genetic
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 1 1 1 Negative Genetic
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Positive Genetic
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Positive Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
BFR2 YDR299W Component of the SSU and 90S preribosomes genetic 1 1 1 Negative Genetic
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing genetic 1 1 1 Positive Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Positive Genetic
NOP4 YPL043W Nucleolar protein genetic 1 1 1 Positive Genetic
NOP7 YGR103W Component of several different pre-ribosomal particles genetic 1 1 1 Positive Genetic
RPL17A YKL180W Ribosomal 60S subunit protein L17A genetic 1 1 1 Positive Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
POP5 YAL033W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Positive Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
LTO1 YNL260C Substrate-specific adaptor protein involved in apo-Rli1p maturation genetic 1 1 1 Negative Genetic
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes genetic 1 1 1 Positive Genetic
RRP14 YKL082C Essential protein, constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) genetic 1 1 1 Positive Genetic
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Synthetic Growth Defect
RPO31 YOR116C RNA polymerase III largest subunit C160 genetic 1 1 1 Positive Genetic
RPB4 YJL140W RNA polymerase II subunit B32 genetic 1 1 1 Positive Genetic
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export genetic 1 1 1 Negative Genetic
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
NPL6 YMR091C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase genetic 1 1 1 Positive Genetic
PRP40 YKL012W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
PRE8 YML092C Alpha 2 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Positive Genetic
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling genetic 1 1 1 Negative Genetic
HGH1 YGR187C Chaperone protein for translation factor eEF2 genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Negative Genetic
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Positive Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Positive Genetic
CAF40 YNL288W Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Positive Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Positive Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
CDC45 YLR103C DNA replication initiation factor genetic 1 1 1 Synthetic Lethality
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 1 1 1 Negative Genetic
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 1 1 1 Negative Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B genetic 1 1 1 Positive Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
IRR1 YIL026C Subunit of the cohesin complex genetic 1 1 1 Negative Genetic
IST1 YNL265C Protein with positive role in the multivesicular body sorting pathway genetic 1 1 1 Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Synthetic Growth Defect
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
IMG1 YCR046C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
FYV4 YHR059W Protein of unknown function genetic 1 1 1 Negative Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Synthetic Growth Defect
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Negative Genetic
MTR10 YOR160W Nuclear import receptor genetic 1 1 1 Negative Genetic
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
NBP35 YGL091C Essential cytoplasmic iron-sulfur cluster binding protein genetic 1 1 1 Negative Genetic
INO80 YGL150C Nucleosome spacing factor genetic 1 1 1 Negative Genetic
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 1 1 1 Negative Genetic
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex genetic 1 1 1 Negative Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Positive Genetic
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Growth Defect
HTA1 YDR225W Histone H2A physical 1 1 1 Reconstituted Complex
PRP31 YGR091W Splicing factor genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Synthetic Rescue
ESF2 YNR054C Essential nucleolar protein involved in pre-18S rRNA processing genetic 1 1 1 Negative Genetic
RAD23 YEL037C Protein with ubiquitin-like N terminus genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
RAD3 YER171W 5' to 3' DNA helicase genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
REF2 YDR195W RNA-binding protein genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Positive Genetic
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RNA14 YMR061W Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NUT2 YPR168W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPB11 YOL005C RNA polymerase II subunit B12.5 genetic 1 1 1 Negative Genetic
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 1 1 1 Negative Genetic
RPB9 YGL070C RNA polymerase II subunit B12.6 genetic 1 1 1 Synthetic Growth Defect
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
MLH2 YLR035C Protein involved in mismatch repair and meiotic recombination genetic 1 1 1 Positive Genetic
RPO26 YPR187W RNA polymerase subunit ABC23 genetic 1 1 1 Negative Genetic
RRI1 YDL216C Catalytic subunit of the COP9 signalosome (CSN) complex genetic 1 1 1 Negative Genetic
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Synthetic Growth Defect
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 1 1 1 Negative Genetic
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
SEC21 YNL287W Gamma subunit of coatomer genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Negative Genetic
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Synthetic Growth Defect
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 1 1 1 Positive Genetic
SEC17 YBL050W Alpha-SNAP cochaperone genetic 1 1 1 Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
SME1 YOR159C Core Sm protein Sm E genetic 1 1 1 Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Negative Genetic
PRP11 YDL043C Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
SNF12 YNR023W 73 kDa subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
SPO7 YAL009W Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Positive Genetic
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Growth Defect
SRO9 YCL037C Cytoplasmic RNA-binding protein genetic 1 1 1 Positive Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
SEN54 YPL083C Subunit of the tRNA splicing endonuclease genetic 1 1 1 Negative Genetic
HEM13 YDR044W Coproporphyrinogen III oxidase genetic 1 1 1 Negative Genetic
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
FDH1 YOR388C NAD(+)-dependent formate dehydrogenase genetic 1 1 1 Negative Genetic
SPP1 YPL138C Subunit of COMPASS (Set1C) genetic 1 1 1 Synthetic Lethality
LSM12 YHR121W Protein of unknown function that may function in RNA processing genetic 1 1 1 Negative Genetic
NTE1 YML059C Serine esterase genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Growth Defect
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Positive Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
ACO1 YLR304C Aconitase genetic 1 1 1 Negative Genetic
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor genetic 1 1 1 Positive Genetic
LAM5 YFL042C Putative sterol transfer protein genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 1 1 1 Biochemical Activity
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Negative Genetic
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Negative Genetic
SER1 YOR184W 3-phosphoserine aminotransferase genetic 1 1 1 Negative Genetic
DMA2 YNL116W Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Negative Genetic
HTB1 YDR224C Histone H2B physical 1 1 1 Reconstituted Complex
CMP2 YML057W Calcineurin A genetic 1 1 1 Negative Genetic
HSH49 YOR319W U2-snRNP associated splicing factor genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
ILV5 YLR355C Acetohydroxyacid reductoisomerase and mtDNA binding protein genetic 1 1 1 Negative Genetic
HXT6 YDR343C High-affinity glucose transporter genetic 1 1 1 Negative Genetic
LCP5 YER127W Essential protein involved in maturation of 18S rRNA genetic 1 1 1 Negative Genetic
ESL2 YKR096W hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Negative Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Positive Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
ERG27 YLR100W 3-keto sterol reductase genetic 1 1 1 Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
PSK2 YOL045W PAS-domain containing serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Positive Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Positive Genetic
DSS4 YPR017C Guanine nucleotide dissociation stimulator for Sec4p genetic 1 1 1 Negative Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase genetic 1 1 1 Positive Genetic
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Positive Genetic
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Negative Genetic
PPE1 YHR075C Protein with carboxyl methyl esterase activity genetic 1 1 1 Negative Genetic
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis genetic 1 1 1 Negative Genetic
KEL2 YGR238C Protein that negatively regulates mitotic exit genetic 1 1 1 Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Positive Genetic
MAG1 YER142C 3-methyl-adenine DNA glycosylase genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Synthetic Growth Defect
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
RAD59 YDL059C Protein involved DNA double-strand break repair genetic 1 1 1 Positive Genetic
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 1 1 1 Negative Genetic
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 1 1 1 Negative Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 1 1 1 Negative Genetic
PAC2 YER007W Microtubule effector required for tubulin heterodimer formation genetic 1 1 1 Negative Genetic
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Synthetic Lethality
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Negative Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Negative Genetic
MFB1 YDR219C Mitochondria-associated F-box protein genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
DEF1 YKL054C RNAPII degradation factor genetic 1 1 1 Negative Genetic
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 1 1 1 Negative Genetic
MIC19 YFR011C Component of the MICOS complex genetic 1 1 1 Positive Genetic
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Positive Genetic
FCF1 YDR339C PINc domain endonuclease genetic 1 1 1 Negative Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Positive Genetic
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase genetic 1 1 1 Positive Genetic
PRS2 YER099C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase genetic 1 1 1 Positive Genetic
MET16 YPR167C 3'-phosphoadenylsulfate reductase genetic 1 1 1 Negative Genetic
CHZ1 YER030W Histone chaperone for Htz1p/H2A-H2B dimer genetic 1 1 1 Negative Genetic
QCR7 YDR529C Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
PSO2 YMR137C Nuclease required for DNA single- and double-strand break repair genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Positive Genetic
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Negative Genetic
SNO1 YMR095C Protein of unconfirmed function genetic 1 1 1 Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Positive Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 1 1 1 Negative Genetic
DSL1 YNL258C Peripheral membrane protein needed for Golgi-to-ER retrograde traffic genetic 1 1 1 Negative Genetic
NAS2 YIL007C Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 1 1 1 Negative Genetic
SNF8 YPL002C Component of the ESCRT-II complex genetic 1 1 1 Negative Genetic
DAL82 YNL314W Positive regulator of allophanate inducible genes genetic 1 1 1 Positive Genetic
HCS1 YKL017C Hexameric DNA polymerase alpha-associated DNA helicase A genetic 1 1 1 Negative Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Positive Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Positive Genetic
SAE2 YGL175C Endonuclease required for telomere elongation genetic 1 1 1 Negative Genetic
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
MNS1 YJR131W Alpha-1,2-mannosidase genetic 1 1 1 Negative Genetic
DAS2 YDR020C Putative protein of unknown function genetic 1 1 1 Negative Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Negative Genetic
DLS1 YJL065C Subunit of ISW2/yCHRAC chromatin accessibility complex genetic 1 1 1 Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 1 1 1 Negative Genetic
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 1 1 1 Negative Genetic
SMC5 YOL034W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CWC15 YDR163W Non-essential protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
NNF1 YJR112W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
NHP6A YPR052C High-mobility group (HMG) protein genetic 1 1 1 Phenotypic Suppression
ARP6 YLR085C Actin-related protein that binds nucleosomes physical 1 1 1 Affinity Capture-MS
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 1 1 1 Positive Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Biochemical Activity
TAF4 YMR005W TFIID subunit (48 kDa) genetic 1 1 1 Negative Genetic
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) genetic 1 1 1 Negative Genetic
UBC11 YOR339C Ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
THI6 YPL214C Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Positive Genetic
YML119W YML119W Putative protein of unknown function genetic 1 1 1 Positive Genetic
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression genetic 1 1 1 Positive Genetic
YBL086C YBL086C Protein of unknown function genetic 1 1 1 Positive Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Positive Genetic
YFH1 YDL120W Mitochondrial matrix iron chaperone genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 1 1 1 Positive Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 1 1 1 Negative Genetic
WHI3 YNL197C RNA binding protein that modulates mRNA stability genetic 1 1 1 Positive Genetic
TEP1 YNL128W PTEN homolog with no demonstrated inositol lipid phosphatase activity genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Synthetic Rescue
TCD2 YKL027W tRNA threonylcarbamoyladenosine dehydratase genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
YET2 YMR040W Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
VMA11 YPL234C Vacuolar ATPase V0 domain subunit c' genetic 1 1 1 Negative Genetic
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Negative Genetic
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties genetic 1 1 1 Synthetic Growth Defect
TIP20 YGL145W Peripheral membrane protein required for COPI vesicle fusion to the ER genetic 1 1 1 Positive Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Positive Genetic
TAF11 YML015C TFIID subunit (40 kDa) genetic 1 1 1 Positive Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Positive Genetic
TIM50 YPL063W Essential component of the TIM23 complex genetic 1 1 1 Positive Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Positive Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Positive Genetic
YAT2 YER024W Carnitine acetyltransferase genetic 1 1 1 Positive Genetic
THI5 YFL058W Protein involved in synthesis of the thiamine precursor HMP genetic 1 1 1 Positive Genetic
YGL185C YGL185C Putative protein with sequence similar to hydroxyacid dehydrogenases genetic 1 1 1 Positive Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Positive Genetic
YJL047C-A YJL047C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
YJL107C YJL107C Putative protein of unknown function genetic 1 1 1 Positive Genetic
UBC12 YLR306W Enzyme that mediates the conjugation of Rub1p genetic 1 1 1 Positive Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Positive Genetic
YMR155W YMR155W Putative protein of unknown function genetic 1 1 1 Positive Genetic
YMR175W-A YMR175W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
YMR242W-A YMR242W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
YOR072W-B YOR072W-B Putative protein of unknown function genetic 1 1 1 Positive Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 1 1 1 Positive Genetic
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein genetic 1 1 1 Positive Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi genetic 1 1 1 Negative Genetic
VRG4 YGL225W Golgi GDP-mannose transporter genetic 1 1 1 Negative Genetic
TFC4 YGR047C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
VHT1 YGR065C High-affinity plasma membrane H+-biotin (vitamin H) symporter genetic 1 1 1 Negative Genetic
TOM20 YGR082W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Negative Genetic
UTP25 YIL091C Nucleolar protein genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation genetic 1 1 1 Negative Genetic
URB2 YJR041C Protein required for normal metabolism of the rRNA primary transcript genetic 1 1 1 Negative Genetic
SWD2 YKL018W Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex genetic 1 1 1 Negative Genetic
TFA1 YKL028W TFIIE large subunit genetic 1 1 1 Negative Genetic
UBA1 YKL210W Ubiquitin activating enzyme (E1) genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
UTP21 YLR409C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
YAL064W YAL064W Protein of unknown function genetic 1 1 1 Negative Genetic
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
YDL241W YDL241W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YDR061W YDR061W Protein with similarity to ABC transporter family members genetic 1 1 1 Negative Genetic
YDR262W YDR262W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TRP4 YDR354W Anthranilate phosphoribosyl transferase genetic 1 1 1 Negative Genetic
YER175W-A YER175W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SWP82 YFL049W Member of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
YGK1 YGL101W 5'-deoxynucleotidase genetic 1 1 1 Negative Genetic
YGL140C YGL140C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YIP4 YGL198W Protein that interacts with Rab GTPases genetic 1 1 1 Negative Genetic
ZIP2 YGL249W Meiosis-specific protein genetic 1 1 1 Negative Genetic
YGR161W-C YGR161W-C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TIM13 YGR181W Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
YGR210C YGR210C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YHR022C-A YHR022C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YHR045W YHR045W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YHR213W YHR213W Pseudogenic fragment with similarity to flocculins genetic 1 1 1 Negative Genetic
YIL024C YIL024C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VHR1 YIL056W Transcriptional activator genetic 1 1 1 Negative Genetic
VTC4 YJL012C Vacuolar membrane polyphosphate polymerase genetic 1 1 1 Negative Genetic
TOH1 YJL171C GPI-anchored cell wall protein of unknown function genetic 1 1 1 Negative Genetic
VPS25 YJR102C Component of the ESCRT-II complex genetic 1 1 1 Negative Genetic
YJR124C YJR124C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Negative Genetic
ZRT3 YKL175W Vacuolar membrane zinc transporter genetic 1 1 1 Negative Genetic
VBA5 YKR105C Plasma membrane protein of the Major Facilitator Superfamily (MFS) genetic 1 1 1 Negative Genetic
YLL053C YLL053C Putative protein genetic 1 1 1 Negative Genetic
YLL066W-B YLL066W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
YLR152C YLR152C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YLR154C-G YLR154C-G Putative protein of unknown function genetic 1 1 1 Negative Genetic
YLR285C-A YLR285C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TMA10 YLR327C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
YLR464W YLR464W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YML003W YML003W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YMR084W YMR084W Putative protein of unknown function genetic 1 1 1 Negative Genetic
VBA1 YMR088C Permease of basic amino acids in the vacuolar membrane genetic 1 1 1 Negative Genetic
YMR099C YMR099C Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) genetic 1 1 1 Negative Genetic
YMR262W YMR262W Protein of unknown function genetic 1 1 1 Negative Genetic
YPT53 YNL093W Stress-induced Rab family GTPase genetic 1 1 1 Negative Genetic
YNL190W YNL190W Hydrophilin essential in desiccation-rehydration process genetic 1 1 1 Negative Genetic
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
YNR048W YNR048W Potential noncatalytic subunit for phospholipid translocase Dnf3p genetic 1 1 1 Negative Genetic
YOR008C-A YOR008C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TRS33 YOR115C Core component of TRAPP complexes I, II and IV genetic 1 1 1 Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes genetic 1 1 1 Positive Genetic
TRM2 YKR056W tRNA methyltransferase genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Positive Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Positive Genetic
YIL046W-A YIL046W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
UFE1 YOR075W t-SNARE protein required for retrograde vesicular traffic genetic 1 1 1 Negative Genetic
YPL245W YPL245W Putative protein of unknown function genetic 1 1 1 Positive Genetic
VTC1 YER072W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) genetic 1 1 1 Positive Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Positive Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Negative Genetic
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 1 1 1 Positive Genetic
GCD10 YNL062C Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p genetic 1 1 1 Negative Genetic
BNI5 YNL166C Linker protein responsible for recruitment of myosin to the bud neck genetic 1 1 1 Positive Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Positive Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
BIK1 YCL029C Microtubule-associated protein genetic 1 1 1 Negative Genetic
CBF2 YGR140W Essential kinetochore protein genetic 1 1 1 Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA genetic 1 1 1 Negative Genetic
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Negative Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Positive Genetic
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 1 1 1 Positive Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
SIP5 YMR140W Protein of unknown function genetic 1 1 1 Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
STE6 YKL209C Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
PAM18 YLR008C Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
MGM1 YOR211C Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p genetic 1 1 1 Positive Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Positive Genetic
MKC7 YDR144C GPI-anchored aspartyl protease genetic 1 1 1 Negative Genetic
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation genetic 1 1 1 Negative Genetic
DPH2 YKL191W Protein required for synthesis of diphthamide genetic 1 1 1 Positive Genetic
HRB1 YNL004W Poly(A+) RNA-binding protein genetic 1 1 1 Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 1 1 1 Positive Genetic
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Synthetic Growth Defect
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
HCH1 YNL281W Heat shock protein regulator genetic 1 1 1 Positive Genetic
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 1 1 1 Positive Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Phenotypic Suppression
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
FIR1 YER032W Protein involved in 3' mRNA processing genetic 1 1 1 Positive Genetic
SNZ1 YMR096W Subunit of a two-component pyridoxal-5'-phosphate synthase genetic 1 1 1 Negative Genetic
SPC29 YPL124W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Positive Genetic
MRI1 YPR118W 5'-methylthioribose-1-phosphate isomerase genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex genetic 1 1 1 Positive Genetic
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly genetic 1 1 1 Negative Genetic
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Synthetic Growth Defect
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I genetic 1 1 1 Negative Genetic
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Negative Genetic
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
COX17 YLL009C Copper metallochaperone that transfers copper to Sco1p and Cox11p genetic 1 1 1 Negative Genetic
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 1 1 1 Positive Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Positive Genetic
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Positive Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Positive Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Synthetic Rescue
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Positive Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Negative Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
EMC6 YLL014W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
SLK19 YOR195W Kinetochore-associated protein genetic 1 1 1 Negative Genetic
GTA1 YEL043W Protein of unknown function genetic 1 1 1 Positive Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 1 1 1 Positive Genetic
APM2 YHL019C Protein of unknown function genetic 1 1 1 Negative Genetic
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Negative Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Positive Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Negative Genetic
SMN1 YHR202W Putative AMP hydrolase genetic 1 1 1 Negative Genetic
DSF2 YBR007C Deletion suppressor of mpt5 mutation genetic 1 1 1 Synthetic Growth Defect
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
MRH1 YDR033W Protein that localizes primarily to the plasma membrane genetic 1 1 1 Negative Genetic
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
CPR5 YDR304C Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the ER genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Negative Genetic
GID11 YLR149C Substrate receptor of the glucose-induced degradation-deficient (GID) genetic 1 1 1 Negative Genetic
COQ11 YLR290C Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes genetic 1 1 1 Negative Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
CRS1 YNL247W Cysteinyl-tRNA synthetase genetic 1 1 1 Positive Genetic
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy genetic 1 1 1 Negative Genetic
CAB4 YGR277C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Positive Genetic
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Positive Genetic
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Negative Genetic
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Negative Genetic
RSM24 YDR175C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Positive Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Synthetic Growth Defect
AQY3 YFL054C Putative channel-like protein genetic 1 1 1 Positive Genetic
INA17 YPL099C F1F0 ATPase synthase peripheral stalk assembly factor genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Negative Genetic
MSS51 YLR203C Specific translational activator for the mitochondrial COX1 mRNA genetic 1 1 1 Positive Genetic
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
SMT1 YJL147C Translational repressor of the mitochondrial ATP6/8 mRNA genetic 1 1 1 Positive Genetic
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family genetic 1 1 1 Phenotypic Suppression
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
CSS1 YIL169C Protein of unknown function, secreted when constitutively expressed genetic 1 1 1 Negative Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 1 1 1 Negative Genetic
CUP9 YPL177C Homeodomain-containing transcriptional repressor genetic 1 1 1 Negative Genetic
PFK26 YIL107C 6-phosphofructo-2-kinase genetic 1 1 1 Negative Genetic
RIM4 YHL024W Putative RNA-binding protein genetic 1 1 1 Negative Genetic
OGG1 YML060W Nuclear and mitochondrial glycosylase/lyase genetic 1 1 1 Negative Genetic
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
IRC19 YLL033W Protein of unknown function genetic 1 1 1 Negative Genetic
GEP5 YLR091W Protein of unknown function genetic 1 1 1 Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
RPL20A YMR242C Ribosomal 60S subunit protein L20A genetic 1 1 1 Positive Genetic
SDD3 YOL098C Putative metalloprotease genetic 1 1 1 Negative Genetic
RTR1 YER139C Dual specificity protein phosphatase genetic 1 1 1 Positive Genetic
SQS1 YNL224C Protein that stimulates the ATPase and helicase activities of Prp43p genetic 1 1 1 Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 1 1 1 Positive Genetic
OPY2 YPR075C Integral membrane protein that acts as a membrane anchor for Ste50p genetic 1 1 1 Positive Genetic
CCW22 YDR134C Cell wall protein genetic 1 1 1 Positive Genetic
CAB1 YDR531W Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase genetic 1 1 1 Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Negative Genetic
EMA35 YCR100C Protein involved in protein sorting genetic 1 1 1 Negative Genetic
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Positive Genetic
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Positive Genetic
AIM39 YOL053W Protein of unknown function genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Positive Genetic
SCD6 YPR129W Repressor of translation initiation genetic 1 1 1 Negative Genetic
SGO1 YOR073W Component of the spindle checkpoint genetic 1 1 1 Positive Genetic
DNF2 YDR093W Aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
ALO1 YML086C D-Arabinono-1,4-lactone oxidase genetic 1 1 1 Negative Genetic
CPD1 YGR247W Cyclic nucleotide phosphodiesterase genetic 1 1 1 Negative Genetic
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
PNC1 YGL037C Nicotinamidase that converts nicotinamide to nicotinic acid genetic 1 1 1 Negative Genetic
RBA50 YDR527W Protein involved in transcription genetic 1 1 1 Negative Genetic
SPO11 YHL022C Meiosis-specific protein required for meiotic recombination genetic 1 1 1 Positive Genetic
MET7 YOR241W Folylpolyglutamate synthetase genetic 1 1 1 Negative Genetic
AST2 YER101C Lipid raft associated protein genetic 1 1 1 Negative Genetic
RIP1 YEL024W Ubiquinol-cytochrome-c reductase genetic 1 1 1 Negative Genetic
MAM1 YER106W Monopolin genetic 1 1 1 Positive Genetic
MFG1 YDL233W Regulator of filamentous growth genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
NOP10 YHR072W-A Subunit of box H/ACA snoRNP complex genetic 1 1 1 Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Positive Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
RRT14 YIL127C Putative protein of unknown function genetic 1 1 1 Negative Genetic
INO1 YJL153C Inositol-3-phosphate synthase genetic 1 1 1 Positive Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Positive Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Negative Genetic
MEP2 YNL142W Ammonium permease involved in regulation of pseudohyphal growth genetic 1 1 1 Positive Genetic
DAL2 YIR029W Allantoicase genetic 1 1 1 Negative Genetic
AMD2 YDR242W Putative amidase genetic 1 1 1 Negative Genetic
PHO92 YDR374C Posttranscriptional regulator of phosphate and glucose metabolism genetic 1 1 1 Negative Genetic
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 1 1 1 Positive Genetic
GPI14 YJR013W Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
PFA4 YOL003C Palmitoyltransferase with autoacylation activity genetic 1 1 1 Negative Genetic
FIT2 YOR382W Mannoprotein that is incorporated into the cell wall genetic 1 1 1 Positive Genetic
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly genetic 1 1 1 Negative Genetic
GPI18 YBR004C Functional ortholog of human PIG-V genetic 1 1 1 Negative Genetic
ATG41 YPL250C Protein of unknown function genetic 1 1 1 Negative Genetic
SUT1 YGL162W Zn(II)2Cys6 family transcription factor genetic 1 1 1 Negative Genetic
SMP3 YOR149C Alpha 1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
RSB1 YOR049C Sphingoid long-chain base (LCB) efflux transporter genetic 1 1 1 Phenotypic Enhancement
EFM5 YGR001C S-adenosylmethionine-dependent lysine methyltransferase genetic 1 1 1 Negative Genetic
GRS2 YPR081C Glycine-tRNA synthetase, not expressed under normal growth conditions genetic 1 1 1 Positive Genetic
NCE103 YNL036W Carbonic anhydrase genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Positive Genetic
MIC27 YNL100W Component of the MICOS complex genetic 1 1 1 Negative Genetic
FYV7 YLR068W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Negative Genetic
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Negative Genetic
COS5 YJR161C Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
LEE1 YPL054W Zinc-finger protein of unknown function genetic 1 1 1 Negative Genetic
FMP30 YPL103C Protein with a role in maintaining mitochondrial morphology genetic 1 1 1 Negative Genetic
IRC15 YPL017C Microtubule associated protein genetic 1 1 1 Negative Genetic
SAM3 YPL274W High-affinity S-adenosylmethionine permease genetic 1 1 1 Negative Genetic
ALG11 YNL048W Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
ADY2 YCR010C Acetate transporter required for normal sporulation genetic 1 1 1 Negative Genetic
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Positive Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RIB2 YOL066C Bifunctional DRAP deaminase tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
AIM24 YJR080C Protein with a role in determining mitochondrial architecture genetic 1 1 1 Negative Genetic
QRI5 YLR204W Mitochondrial inner membrane protein genetic 1 1 1 Positive Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Negative Genetic
MNT3 YIL014W Alpha-1,3-mannosyltransferase genetic 1 1 1 Negative Genetic
GYP8 YFL027C GTPase-activating protein for yeast Rab family members genetic 1 1 1 Negative Genetic
ECM38 YLR299W Gamma-glutamyltranspeptidase genetic 1 1 1 Positive Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Positive Genetic
IDP2 YLR174W Cytosolic NADP-specific isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Positive Genetic
MRX20 YFR045W Putative mitochondrial transport protein genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase physical 1 1 1 Affinity Capture-MS
NRK1 YNL129W Nicotinamide riboside kinase genetic 1 1 1 Negative Genetic
HEM4 YOR278W Uroporphyrinogen III synthase genetic 1 1 1 Negative Genetic
RME1 YGR044C Zinc finger protein involved in control of meiosis genetic 1 1 1 Positive Genetic
SDH6 YDR379C-A Mitochondrial protein involved in assembly of succinate dehydrogenase genetic 1 1 1 Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
PHM7 YOL084W Protein of unknown function genetic 1 1 1 Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Positive Genetic
BUD25 YER014C-A Protein involved in bud-site selection genetic 1 1 1 Positive Genetic
SPO22 YIL073C Meiosis-specific protein essential for chromosome synapsis genetic 1 1 1 Negative Genetic
SSP2 YOR242C Sporulation specific protein that localizes to the spore wall genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
SPS4 YOR313C Protein whose expression is induced during sporulation genetic 1 1 1 Positive Genetic
SPR1 YOR190W Sporulation-specific exo-1,3-beta-glucanase genetic 1 1 1 Negative Genetic
PGA1 YNL158W Essential component of GPI-mannosyltransferase II genetic 1 1 1 Negative Genetic
RTR2 YDR066C Protein of unknown function genetic 1 1 1 Negative Genetic