GEnome-wide tool for Multi-scale Modeling
data Extraction and Representation
for Saccharomyces cerevisiae

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.

Standard name	Systematic name	Name description	Type	#Experiments	#Methods	#Publications	Evidence
RAD9	YDR217C	DNA damage-dependent checkpoint protein	genetic	22	5	15	Synthetic Lethality, Synthetic Lethality, Phenotypic Enhancement, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Rescue, Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality
SRS2	YJL092W	DNA helicase and DNA-dependent ATPase	genetic	16	5	12	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Dosage Lethality, Dosage Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality
CSM3	YMR048W	Replication fork associated factor	genetic	16	4	11	Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Phenotypic Enhancement
TOF1	YNL273W	Subunit of a replication-pausing checkpoint complex	genetic	15	4	12	Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Phenotypic Enhancement
SGS1	YMR190C	RecQ family nucleolar DNA helicase	genetic	15	4	12	Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic
RRM3	YHR031C	DNA helicase involved in rDNA replication and Ty1 transposition	genetic	14	2	11	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality
RAD27	YKL113C	5' to 3' exonuclease, 5' flap endonuclease	genetic	13	4	10	Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect
CTF4	YPR135W	Chromatin-associated protein	genetic	12	2	9	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality
CTF18	YMR078C	Subunit of a complex with Ctf8p	genetic	12	4	8	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Synthetic Lethality
DDC1	YPL194W	DNA damage checkpoint protein	genetic	12	4	8	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic
ELG1	YOR144C	Subunit of an alternative replication factor C complex	genetic	12	3	8	Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DIA2	YOR080W	Origin-binding F-box protein	genetic	12	6	7	Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Synthetic Lethality, Synthetic Rescue, Dosage Growth Defect, Negative Genetic, Negative Genetic, Phenotypic Suppression
HTZ1	YOL012C	Histone variant H2AZ	genetic	11	3	10	Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect
RAD52	YML032C	Protein involved in homologous recombination	genetic	11	5	9	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Suppression, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect
RAD24	YER173W	Checkpoint protein	genetic	11	4	7	Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic
HST3	YOR025W	Sirtuin, histone H3 deacetylase	genetic	11	3	7	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality
POL32	YJR043C	Third subunit of DNA polymerase delta	genetic	11	3	7	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect
RAD17	YOR368W	Checkpoint protein	genetic	10	4	7	Synthetic Lethality, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
CTF8	YHR191C	Subunit of a complex with Ctf18p	genetic	10	3	6	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CHL1	YPL008W	Probable DNA helicase	genetic	9	4	7	Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWR1	YDR334W	Swi2/Snf2-related ATPase	genetic	9	3	7	Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect
ARP6	YLR085C	Actin-related protein that binds nucleosomes	genetic	9	2	7	Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
MCM4	YPR019W	Essential helicase component of heterohexameric MCM2-7 complexes	physical	8	2	7	Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
NUP60	YAR002W	FG-nucleoporin component of central core of the nuclear pore complex	genetic	8	2	7	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic
VPS72	YDR485C	Htz1p-binding component of the SWR1 complex	genetic	8	2	6	Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
MMS22	YLR320W	Subunit of E3 ubiquitin ligase complex involved in replication repair	genetic	8	3	5	Positive Genetic, Positive Genetic, Positive Genetic, Synthetic Rescue, Synthetic Rescue, Dosage Growth Defect, Positive Genetic, Positive Genetic
DIA2	YOR080W	Origin-binding F-box protein	physical	8	3	4	Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Biochemical Activity
RAD53	YPL153C	DNA damage response kinase	genetic	7	5	7	Synthetic Lethality, Negative Genetic, Synthetic Rescue, Synthetic Lethality, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic
CIK1	YMR198W	Kinesin-associated protein	genetic	7	3	6	Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic
MEC3	YLR288C	DNA damage and meiotic pachytene checkpoint protein	genetic	7	3	6	Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic
MMS1	YPR164W	Subunit of E3 ubiquitin ligase complex involved in replication repair	genetic	7	2	6	Positive Genetic, Positive Genetic, Positive Genetic, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Positive Genetic
GET2	YER083C	Subunit of the GET complex	genetic	7	2	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
MRE11	YMR224C	Nuclease subunit of the MRX complex with Rad50p and Xrs2p	genetic	7	2	5	Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
BIM1	YER016W	Microtubule plus end-tracking protein	genetic	6	3	6	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect
VPS71	YML041C	Nucleosome-binding component of the SWR1 complex	genetic	6	2	6	Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
DUN1	YDL101C	Cell-cycle checkpoint S/T protein kinase	genetic	6	4	5	Dosage Rescue, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic
CDC13	YDL220C	Single stranded DNA-binding protein found at TG1-3 telomere G-tails	genetic	6	3	5	Synthetic Growth Defect, Dosage Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
MCM3	YEL032W	Protein involved in DNA replication	physical	6	2	5	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
NUP133	YKR082W	Subunit of Nup84p subcomplex of nuclear pore complex (NPC)	genetic	6	2	5	Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic
SIC1	YLR079W	Cyclin-dependent kinase inhibitor (CKI)	genetic	6	2	5	Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic
SEN1	YLR430W	ATP-dependent 5' to 3' RNA/DNA and DNA helicase	genetic	6	4	4	Synthetic Lethality, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Lethality, Synthetic Growth Defect
DCC1	YCL016C	Subunit of a complex with Ctf8p and Ctf18p	genetic	6	3	4	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
DPB3	YBR278W	Third-largest subunit of DNA polymerase II (DNA polymerase epsilon)	genetic	6	2	4	Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
XRS2	YDR369C	FHA domain-containing component of the Mre11 complex	genetic	6	2	4	Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
VIP1	YLR410W	Bifunctional inositol pyrophosphate kinase and phosphatase	genetic	6	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ISW2	YOR304W	ATP-dependent DNA translocase involved in chromatin remodeling	genetic	6	4	3	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Suppression, Synthetic Rescue, Negative Genetic
RTT107	YHR154W	BRCA1 C-terminal domain protein needed for recovery from DNA damage	genetic	6	4	3	Positive Genetic, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Dosage Growth Defect
RTT101	YJL047C	Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex	genetic	6	4	3	Positive Genetic, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Dosage Growth Defect
HTA1	YDR225W	Histone H2A	genetic	6	3	3	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic
ASF1	YJL115W	Nucleosome assembly factor	genetic	5	3	5	Dosage Rescue, Positive Genetic, Positive Genetic, Synthetic Rescue, Synthetic Rescue
SWC5	YBR231C	Component of the SWR1 complex	genetic	5	2	5	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SML1	YML058W	Ribonucleotide reductase inhibitor	genetic	5	1	5	Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
CDC6	YJL194W	Essential ATP-binding protein required for DNA replication	genetic	5	3	4	Dosage Lethality, Synthetic Rescue, Negative Genetic, Negative Genetic, Negative Genetic
SLD5	YDR489W	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p)	physical	5	3	4	Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western
POL3	YDL102W	Catalytic subunit of DNA polymerase delta	genetic	5	3	4	Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RAD51	YER095W	Strand exchange protein	genetic	5	3	4	Dosage Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
CDC45	YLR103C	DNA replication initiation factor	genetic	5	2	4	Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality
MCD1	YDL003W	Essential alpha-kleisin subunit of the cohesin complex	genetic	5	2	4	Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
POL1	YNL102W	Catalytic subunit of the DNA polymerase I alpha-primase complex	genetic	5	2	4	Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect
CDC45	YLR103C	DNA replication initiation factor	physical	5	1	4	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RFC5	YBR087W	Subunit of heteropentameric Replication factor C (RF-C)	genetic	5	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SPT2	YER161C	Protein involved in negative regulation of transcription	genetic	5	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SMC1	YFL008W	Subunit of the multiprotein cohesin complex	genetic	5	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD50	YNL250W	Subunit of MRX complex with Mre11p and Xrs2p	genetic	5	3	3	Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
ORC2	YBR060C	Subunit of the origin recognition complex (ORC)	genetic	5	2	3	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
SWC3	YAL011W	Protein of unknown function	genetic	5	2	3	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
IPK1	YDR315C	Inositol 1,3,4,5,6-pentakisphosphate 2-kinase	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HOG1	YLR113W	Mitogen-activated protein kinase involved in osmoregulation	physical	5	3	2	Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Biochemical Activity
POL2	YNL262W	Catalytic subunit of DNA polymerase (II) epsilon	physical	5	2	2	Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
MCM2	YBL023C	Protein involved in DNA replication	physical	4	2	4	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
CDH1	YGL003C	Activator of anaphase-promoting complex/cyclosome (APC/C)	genetic	4	2	4	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CSM3	YMR048W	Replication fork associated factor	physical	4	2	4	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
BUB1	YGR188C	Protein kinase involved in the cell cycle checkpoint into anaphase	genetic	4	2	4	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
PPH3	YDR075W	Catalytic subunit of protein phosphatase PP4 complex	genetic	4	2	4	Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
POL2	YNL262W	Catalytic subunit of DNA polymerase (II) epsilon	genetic	4	4	3	Synthetic Lethality, Dosage Rescue, Synthetic Growth Defect, Negative Genetic
SLX4	YLR135W	Endonuclease involved in processing DNA	genetic	4	4	3	Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Growth Defect
DNA2	YHR164C	ATP-dependent 5'-flap endonuclease and DNA helicase	genetic	4	3	3	Synthetic Lethality, Synthetic Rescue, Negative Genetic, Negative Genetic
DPB11	YJL090C	DNA replication initiation protein	genetic	4	3	3	Synthetic Lethality, Negative Genetic, Negative Genetic, Dosage Growth Defect
BUB3	YOR026W	Kinetochore checkpoint WD40 repeat protein	genetic	4	3	3	Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic
HST4	YDR191W	NAD(+)-dependent protein deacetylase	genetic	4	3	3	Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality
CHD1	YER164W	Chromatin remodeler that regulates various aspects of transcription	genetic	4	2	3	Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic
KAR3	YPR141C	Minus-end-directed microtubule motor	genetic	4	2	3	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
TOF1	YNL273W	Subunit of a replication-pausing checkpoint complex	physical	4	2	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
RNR1	YER070W	Major isoform of large subunit of ribonucleotide-diphosphate reductase	genetic	4	2	3	Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Dosage Rescue
SWC4	YGR002C	Component of the Swr1p complex that incorporates Htz1p into chromatin	genetic	4	2	3	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
CDC8	YJR057W	Nucleoside monophosphate and nucleoside diphosphate kinase	genetic	4	2	3	Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SCC2	YDR180W	Subunit of cohesin loading factor (Scc2p-Scc4p)	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LGE1	YPL055C	Protein involved in histone H2B ubiquitination	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TEL1	YBL088C	Protein kinase primarily involved in telomere length regulation	genetic	4	3	2	Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Rescue
CMR1	YDL156W	Nuclear protein with role in transcription, protein quality control	genetic	4	3	1	Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression
SIR2	YDL042C	Conserved NAD+ dependent histone deacetylase of the Sirtuin family	genetic	3	3	3	Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression
SAE2	YGL175C	Endonuclease required for telomere elongation	genetic	3	3	3	Synthetic Rescue, Synthetic Growth Defect, Negative Genetic
DPB2	YPR175W	Second largest subunit of DNA polymerase II (DNA polymerase epsilon)	physical	3	2	3	Two-hybrid, Affinity Capture-Western, Affinity Capture-Western
MEC1	YBR136W	Genome integrity checkpoint protein and PI kinase superfamily member	genetic	3	2	3	Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect
MCM4	YPR019W	Essential helicase component of heterohexameric MCM2-7 complexes	genetic	3	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RMI1	YPL024W	Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex	genetic	3	2	3	Negative Genetic, Synthetic Growth Defect, Negative Genetic
TOP3	YLR234W	DNA Topoisomerase III	genetic	3	2	3	Negative Genetic, Synthetic Lethality, Negative Genetic
NUP84	YDL116W	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC)	genetic	3	2	3	Negative Genetic, Negative Genetic, Synthetic Lethality
YAF9	YNL107W	Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes	genetic	3	2	3	Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
YKU70	YMR284W	Subunit of the telomeric Ku complex (Yku70p-Yku80p)	genetic	3	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RTT109	YLL002W	Histone acetyltransferase	genetic	3	2	3	Synthetic Rescue, Positive Genetic, Synthetic Rescue
RFA2	YNL312W	Subunit of heterotrimeric Replication Protein A (RPA)	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
ESA1	YOR244W	Catalytic subunit of the histone acetyltransferase complex (NuA4)	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
CDC48	YDL126C	AAA ATPase with protein-unfoldase activity	genetic	3	2	2	Synthetic Growth Defect, Negative Genetic, Negative Genetic
SLD5	YDR489W	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p)	genetic	3	2	2	Synthetic Growth Defect, Negative Genetic, Negative Genetic
RAD53	YPL153C	DNA damage response kinase	physical	3	2	2	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
ORC5	YNL261W	Subunit of the origin recognition complex (ORC)	genetic	3	2	2	Synthetic Lethality, Synthetic Lethality, Synthetic Rescue
ORC6	YHR118C	Subunit of the origin recognition complex (ORC)	genetic	3	2	2	Synthetic Rescue, Negative Genetic, Negative Genetic
POL31	YJR006W	Subunit of DNA polymerase delta (polymerase III)	genetic	3	2	2	Synthetic Growth Defect, Negative Genetic, Negative Genetic
RAD6	YGL058W	Ubiquitin-conjugating enzyme (E2)	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement
MET7	YOR241W	Folylpolyglutamate synthetase	genetic	3	2	2	Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
CDC23	YHR166C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MCM6	YGL201C	Protein involved in DNA replication	physical	3	1	2	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
CSE2	YNR010W	Subunit of the RNA polymerase II mediator complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MED1	YPR070W	Subunit of the RNA polymerase II mediator complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MCM2	YBL023C	Protein involved in DNA replication	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CDC20	YGL116W	Activator of anaphase-promoting complex/cyclosome (APC/C)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RFC4	YOL094C	Subunit of heteropentameric Replication factor C (RF-C)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
VPS8	YAL002W	Membrane-binding component of the CORVET complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
POL12	YBL035C	B subunit of DNA polymerase alpha-primase complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
TAF5	YBR198C	Subunit (90 kDa) of TFIID and SAGA complexes	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
NUM1	YDR150W	Protein required for nuclear migration	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
NBP2	YDR162C	Protein involved in the HOG (high osmolarity glycerol) pathway	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SPS2	YDR522C	Protein expressed during sporulation	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MSP1	YGR028W	Highly-conserved N-terminally anchored AAA-ATPase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PMT6	YGR199W	Protein O-mannosyltransferase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PHO23	YNL097C	Component of the Rpd3L histone deacetylase complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RLF2	YPR018W	Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PSF1	YDR013W	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SMC3	YJL074C	Subunit of the multiprotein cohesin complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PRI2	YKL045W	Subunit of DNA primase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
ORC3	YLL004W	Subunit of the origin recognition complex (ORC)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
NHP10	YDL002C	Non-essential INO80 chromatin remodeling complex subunit	genetic	3	3	1	Synthetic Growth Defect, Phenotypic Suppression, Synthetic Rescue
MMS21	YEL019C	Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex	genetic	2	2	2	Synthetic Rescue, Phenotypic Enhancement
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	genetic	2	2	2	Phenotypic Enhancement, Synthetic Growth Defect
CHK1	YBR274W	Serine/threonine kinase and DNA damage checkpoint effector	genetic	2	2	2	Synthetic Rescue, Synthetic Lethality
MMS4	YBR098W	Subunit of structure-specific Mms4p-Mus81p endonuclease	genetic	2	2	2	Phenotypic Suppression, Negative Genetic
LRS4	YDR439W	Nucleolar protein that forms a complex with Csm1p	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
SLT2	YHR030C	Serine/threonine MAP kinase	genetic	2	2	2	Dosage Rescue, Negative Genetic
POL30	YBR088C	Proliferating cell nuclear antigen (PCNA)	genetic	2	2	2	Negative Genetic, Synthetic Lethality
PIF1	YML061C	DNA helicase, potent G-quadruplex DNA binder/unwinder	genetic	2	2	2	Dosage Growth Defect, Negative Genetic
RPN4	YDL020C	Transcription factor that stimulates expression of proteasome genes	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
TAF1	YGR274C	TFIID subunit, involved in RNA pol II transcription initiation	genetic	2	2	2	Synthetic Lethality, Negative Genetic
SMT3	YDR510W	Ubiquitin-like protein of the SUMO family	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
RAD1	YPL022W	Single-stranded DNA endonuclease (with Rad10p)	genetic	2	2	2	Synthetic Lethality, Synthetic Growth Defect
CTK1	YKL139W	Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I)	genetic	2	1	2	Negative Genetic, Negative Genetic
DOA1	YKL213C	WD-repeat protein involved in ubiquitin-mediated protein degradation	genetic	2	1	2	Negative Genetic, Negative Genetic
ENO2	YHR174W	Enolase II, a phosphopyruvate hydratase	genetic	2	1	2	Negative Genetic, Negative Genetic
ARP8	YOR141C	Nuclear actin-related protein involved in chromatin remodeling	genetic	2	1	2	Negative Genetic, Negative Genetic
LTE1	YAL024C	Protein similar to GDP/GTP exchange factors	genetic	2	1	2	Synthetic Growth Defect, Synthetic Growth Defect
ELM1	YKL048C	Serine/threonine protein kinase	genetic	2	1	2	Negative Genetic, Negative Genetic
CDC27	YBL084C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	2	1	2	Negative Genetic, Negative Genetic
BRE5	YNR051C	Ubiquitin protease cofactor	genetic	2	1	2	Negative Genetic, Negative Genetic
IES2	YNL215W	Protein that associates with the INO80 chromatin remodeling complex	genetic	2	1	2	Negative Genetic, Negative Genetic
GIM4	YEL003W	Subunit of the heterohexameric cochaperone prefoldin complex	genetic	2	1	2	Positive Genetic, Positive Genetic
AIM44	YPL158C	Regulator of Cdc42p and Rho1p	genetic	2	1	2	Negative Genetic, Negative Genetic
SPT16	YGL207W	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p)	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
NUP120	YKL057C	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC)	genetic	2	1	2	Synthetic Lethality, Synthetic Lethality
PRI1	YIR008C	Subunit of DNA primase	genetic	2	1	2	Negative Genetic, Negative Genetic
SLX8	YER116C	Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex	genetic	2	1	2	Negative Genetic, Negative Genetic
SEC22	YLR268W	R-SNARE protein	genetic	2	1	2	Negative Genetic, Negative Genetic
RFA1	YAR007C	Subunit of heterotrimeric Replication Protein A (RPA)	genetic	2	1	2	Negative Genetic, Negative Genetic
SLX5	YDL013W	Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex	genetic	2	1	2	Negative Genetic, Negative Genetic
MUS81	YDR386W	Subunit of structure-specific Mms4p-Mus81p endonuclease	genetic	2	1	2	Negative Genetic, Negative Genetic
YPT6	YLR262C	Rab family GTPase	genetic	2	1	2	Positive Genetic, Positive Genetic
RIC1	YLR039C	Protein involved in retrograde transport to the cis-Golgi network	genetic	2	1	2	Positive Genetic, Positive Genetic
PPE1	YHR075C	Protein with carboxyl methyl esterase activity	genetic	2	1	2	Positive Genetic, Positive Genetic
YKL069W	YKL069W	Methionine-R-sulfoxide reductase	genetic	2	1	2	Negative Genetic, Negative Genetic
SRN2	YLR119W	Component of the ESCRT-I complex	genetic	2	1	2	Negative Genetic, Negative Genetic
RAD23	YEL037C	Protein with ubiquitin-like N terminus	genetic	2	1	2	Negative Genetic, Negative Genetic
PBS2	YJL128C	MAP kinase kinase of the HOG signaling pathway	genetic	2	1	2	Negative Genetic, Negative Genetic
TAF8	YML114C	TFIID subunit (65 kDa)	genetic	2	1	2	Negative Genetic, Negative Genetic
TPM1	YNL079C	Major isoform of tropomyosin	genetic	2	1	2	Positive Genetic, Positive Genetic
RIM21	YNL294C	pH sensor molecule, component of the RIM101 pathway	genetic	2	1	2	Negative Genetic, Negative Genetic
HRQ1	YDR291W	3'-5' DNA helicase of the conserved RecQ family	genetic	2	1	2	Negative Genetic, Negative Genetic
HTA2	YBL003C	Histone H2A	genetic	2	2	1	Synthetic Growth Defect, Synthetic Lethality
BIR1	YJR089W	Subunit of chromosomal passenger complex (CPC)	genetic	2	2	1	Synthetic Growth Defect, Negative Genetic
SLT2	YHR030C	Serine/threonine MAP kinase	physical	2	2	1	Biochemical Activity, Affinity Capture-Western
PSK1	YAL017W	PAS domain-containing serine/threonine protein kinase	physical	2	2	1	Biochemical Activity, Affinity Capture-Western
SNF1	YDR477W	AMP-activated S/T protein kinase	physical	2	2	1	Biochemical Activity, Affinity Capture-Western
POP2	YNR052C	Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation	genetic	2	2	1	Synthetic Growth Defect, Phenotypic Enhancement
GLC7	YER133W	Type 1 S/T protein phosphatase (PP1) catalytic subunit	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
HOL1	YNR055C	Putative transporter in the major facilitator superfamily	genetic	2	1	1	Negative Genetic, Negative Genetic
ARD1	YHR013C	Subunit of protein N-terminal acetyltransferase NatA	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
EPL1	YFL024C	Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DPB4	YDR121W	Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex	genetic	2	1	1	Phenotypic Enhancement, Phenotypic Enhancement
MCM5	YLR274W	Component of the Mcm2-7 hexameric helicase complex	genetic	2	1	1	Negative Genetic, Negative Genetic
GET1	YGL020C	Subunit of the GET complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HHT1	YBR010W	Histone H3	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
ATG13	YPR185W	Regulatory subunit of the Atg1p signaling complex	genetic	2	1	1	Negative Genetic, Negative Genetic
APC5	YOR249C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	2	1	1	Negative Genetic, Negative Genetic
CLB5	YPR120C	B-type cyclin involved in DNA replication during S phase	genetic	2	1	1	Phenotypic Enhancement, Phenotypic Enhancement
IOC4	YMR044W	Member of a complex (Isw1b) with Isw1p and Ioc2p	genetic	2	1	1	Negative Genetic, Negative Genetic
GLN3	YER040W	Transcriptional activator in nitrogen catabolite repression system	genetic	2	1	1	Phenotypic Enhancement, Phenotypic Enhancement
MCM7	YBR202W	Component of the Mcm2-7 hexameric helicase complex	genetic	2	1	1	Negative Genetic, Negative Genetic
PSF2	YJL072C	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p)	genetic	2	1	1	Negative Genetic, Negative Genetic
VAM7	YGL212W	Vacuolar SNARE protein	genetic	2	1	1	Negative Genetic, Negative Genetic
RPA34	YJL148W	RNA polymerase I subunit A34.5	genetic	2	1	1	Negative Genetic, Negative Genetic
NUP188	YML103C	Subunit of the inner ring of the nuclear pore complex (NPC)	genetic	2	1	1	Positive Genetic, Positive Genetic
VPS9	YML097C	Guanine nucleotide exchange factor (GEF) and ubiquitin receptor	genetic	2	1	1	Negative Genetic, Negative Genetic
VPS27	YNR006W	Endosomal protein that forms a complex with Hse1p	genetic	2	1	1	Negative Genetic, Negative Genetic
URA7	YBL039C	Major CTP synthase isozyme (see also URA8)	genetic	2	1	1	Phenotypic Enhancement, Phenotypic Enhancement
RAD18	YCR066W	E3 ubiquitin ligase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NPT1	YOR209C	Nicotinate phosphoribosyltransferase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NAT1	YDL040C	Subunit of protein N-terminal acetyltransferase NatA	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NSE4	YDL105W	Component of the SMC5-SMC6 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
SCC4	YER147C	Subunit of cohesin loading factor (Scc2p-Scc4p)	genetic	2	1	1	Negative Genetic, Negative Genetic
SPT15	YER148W	TATA-binding protein (TBP)	genetic	2	1	1	Negative Genetic, Negative Genetic
SLD3	YGL113W	Protein involved in the initiation of DNA replication	genetic	2	1	1	Negative Genetic, Negative Genetic
TAH11	YJR046W	DNA replication licensing factor	genetic	2	1	1	Negative Genetic, Negative Genetic
RFC2	YJR068W	Subunit of heteropentameric Replication factor C (RF-C)	genetic	2	1	1	Negative Genetic, Negative Genetic
VTI1	YMR197C	Protein involved in cis-Golgi membrane traffic	genetic	2	1	1	Negative Genetic, Negative Genetic
ORC4	YPR162C	Subunit of the origin recognition complex (ORC)	genetic	2	1	1	Negative Genetic, Negative Genetic
RPC82	YPR190C	RNA polymerase III subunit C82	genetic	2	1	1	Negative Genetic, Negative Genetic
GAA1	YLR088W	Subunit of the GPI:protein transamidase complex	genetic	2	1	1	Negative Genetic, Negative Genetic
ARG2	YJL071W	Acetylglutamate synthase (glutamate N-acetyltransferase)	genetic	2	1	1	Phenotypic Enhancement, Phenotypic Enhancement
SFP1	YLR403W	Regulates transcription of ribosomal protein and biogenesis genes	regulation	1	1	1	DNA to cDNA expression microarray evidence
MED2	YDL005C	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MED4	YOR174W	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MBP1	YDL056W	Transcription factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CDC73	YLR418C	Component of the Paf1p complex	genetic	1	1	1	Phenotypic Enhancement
GWT1	YJL091C	Protein involved in the inositol acylation of GlcN-PI	physical	1	1	1	Affinity Capture-MS
ARP4	YJL081C	Nuclear actin-related protein involved in chromatin remodeling	genetic	1	1	1	Negative Genetic
EAF1	YDR359C	Component of the NuA4 histone acetyltransferase complex	genetic	1	1	1	Synthetic Growth Defect
IMH1	YLR309C	Protein involved in vesicular transport	genetic	1	1	1	Negative Genetic
BRR2	YER172C	RNA-dependent ATPase RNA helicase (DEIH box)	genetic	1	1	1	Negative Genetic
BRE1	YDL074C	E3 ubiquitin ligase	genetic	1	1	1	Negative Genetic
LSM1	YJL124C	Lsm (Like Sm) protein	genetic	1	1	1	Positive Genetic
HPR1	YDR138W	Subunit of THO/TREX complexes	genetic	1	1	1	Synthetic Growth Defect
DST1	YGL043W	General transcription elongation factor TFIIS	genetic	1	1	1	Negative Genetic
KAP95	YLR347C	Karyopherin beta	genetic	1	1	1	Negative Genetic
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	physical	1	1	1	Affinity Capture-RNA
ACC1	YNR016C	Acetyl-CoA carboxylase, biotin containing enzyme	genetic	1	1	1	Negative Genetic
AOS1	YPR180W	Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p	genetic	1	1	1	Negative Genetic
APC1	YNL172W	Largest subunit of the Anaphase-Promoting Complex/Cyclosome	genetic	1	1	1	Negative Genetic
ARO1	YDR127W	Pentafunctional arom protein	genetic	1	1	1	Negative Genetic
CDC14	YFR028C	Protein phosphatase required for mitotic exit	genetic	1	1	1	Negative Genetic
CDC28	YBR160W	Cyclin-dependent kinase (CDK) catalytic subunit	physical	1	1	1	Affinity Capture-MS
CDC28	YBR160W	Cyclin-dependent kinase (CDK) catalytic subunit	genetic	1	1	1	Synthetic Growth Defect
CDC11	YJR076C	Component of the septin ring that is required for cytokinesis	genetic	1	1	1	Negative Genetic
CDC12	YHR107C	Component of the septin ring that is required for cytokinesis	genetic	1	1	1	Positive Genetic
COX6	YHR051W	Subunit VI of cytochrome c oxidase (Complex IV)	genetic	1	1	1	Negative Genetic
CIA2	YHR122W	Component of cytosolic iron-sulfur protein assembly (CIA) machinery	genetic	1	1	1	Negative Genetic
GLO3	YER122C	ADP-ribosylation factor GTPase activating protein (ARF GAP)	genetic	1	1	1	Negative Genetic
ERV25	YML012W	Member of the p24 family involved in ER to Golgi transport	genetic	1	1	1	Negative Genetic
ESP1	YGR098C	Separase/separin, a caspase-like cysteine protease	genetic	1	1	1	Positive Genetic
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	physical	1	1	1	Affinity Capture-RNA
HHF2	YNL030W	Histone H4	genetic	1	1	1	Synthetic Growth Defect
IPP1	YBR011C	Cytoplasmic inorganic pyrophosphatase (PPase)	genetic	1	1	1	Negative Genetic
ISW1	YBR245C	ATPase subunit of imitation-switch (ISWI) class chromatin remodelers	physical	1	1	1	Affinity Capture-RNA
HSL1	YKL101W	Nim1p-related protein kinase	genetic	1	1	1	Negative Genetic
MCM5	YLR274W	Component of the Mcm2-7 hexameric helicase complex	physical	1	1	1	Affinity Capture-Western
MCM6	YGL201C	Protein involved in DNA replication	genetic	1	1	1	Negative Genetic
MED11	YMR112C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
FAB1	YFR019W	1-phosphatidylinositol-3-phosphate 5-kinase	genetic	1	1	1	Negative Genetic
MEC1	YBR136W	Genome integrity checkpoint protein and PI kinase superfamily member	physical	1	1	1	Biochemical Activity
MPH1	YIR002C	3'-5' DNA helicase involved in error-free bypass of DNA lesions	genetic	1	1	1	Negative Genetic
GIM3	YNL153C	Subunit of the heterohexameric cochaperone prefoldin complex	genetic	1	1	1	Negative Genetic
GIM5	YML094W	Subunit of the heterohexameric cochaperone prefoldin complex	genetic	1	1	1	Positive Genetic
CWC22	YGR278W	Spliceosome-associated protein that is required for pre-mRNA splicing	genetic	1	1	1	Negative Genetic
INO4	YOL108C	Transcription factor involved in phospholipid synthesis	genetic	1	1	1	Positive Genetic
MET18	YIL128W	Component of cytosolic iron-sulfur protein assembly (CIA) machinery	genetic	1	1	1	Negative Genetic
ILV1	YER086W	Threonine deaminase, catalyzes first step in isoleucine biosynthesis	genetic	1	1	1	Negative Genetic
ANP1	YEL036C	Subunit of the alpha-1,6 mannosyltransferase complex	genetic	1	1	1	Positive Genetic
MNN10	YDR245W	Subunit of a Golgi mannosyltransferase complex	genetic	1	1	1	Negative Genetic
INP52	YNL106C	Polyphosphatidylinositol phosphatase	genetic	1	1	1	Synthetic Growth Defect
GCN5	YGR252W	Catalytic subunit of ADA and SAGA histone acetyltransferase complexes	genetic	1	1	1	Positive Genetic
HFI1	YPL254W	Adaptor protein required for structural integrity of the SAGA complex	genetic	1	1	1	Negative Genetic
HYP2	YEL034W	Translation elongation factor eIF-5A	genetic	1	1	1	Negative Genetic
ASA1	YPR085C	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	1	1	1	Negative Genetic
HTB1	YDR224C	Histone H2B	genetic	1	1	1	Synthetic Growth Defect
HIR3	YJR140C	Subunit of the HIR complex	genetic	1	1	1	Negative Genetic
CDC9	YDL164C	DNA ligase I found in nucleus and mitochondria	genetic	1	1	1	Phenotypic Suppression
KAP122	YGL016W	Karyopherin beta	genetic	1	1	1	Negative Genetic
EST1	YLR233C	TLC1 RNA-associated factor involved in telomere length regulation	genetic	1	1	1	Synthetic Growth Defect
HUL5	YGL141W	Multiubiquitin chain assembly factor (E4)	genetic	1	1	1	Negative Genetic
CIN8	YEL061C	Bipolar kinesin motor protein	genetic	1	1	1	Synthetic Growth Defect
KSP1	YHR082C	Serine/threonine protein kinase	genetic	1	1	1	Negative Genetic
HHT1	YBR010W	Histone H3	physical	1	1	1	Affinity Capture-MS
CTF4	YPR135W	Chromatin-associated protein	physical	1	1	1	Affinity Capture-Western
LHS1	YKL073W	Molecular chaperone of the endoplasmic reticulum lumen	genetic	1	1	1	Positive Genetic
MEH1	YKR007W	Subunit of the EGO/GSE complex	genetic	1	1	1	Negative Genetic
DBF2	YGR092W	Ser/Thr kinase involved in transcription and stress response	genetic	1	1	1	Negative Genetic
FUS3	YBL016W	Mitogen-activated serine/threonine protein kinase involved in mating	genetic	1	1	1	Positive Genetic
CBR1	YIL043C	Cytochrome b reductase and NADH-dependent reductase for Dph3p	genetic	1	1	1	Phenotypic Enhancement
CDC7	YDL017W	S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase)	genetic	1	1	1	Synthetic Rescue
MMS22	YLR320W	Subunit of E3 ubiquitin ligase complex involved in replication repair	physical	1	1	1	Affinity Capture-MS
CSM1	YCR086W	Nucleolar protein that mediates homolog segregation during meiosis I	genetic	1	1	1	Synthetic Growth Defect
MCM10	YIL150C	Essential chromatin-associated protein	genetic	1	1	1	Negative Genetic
CAK1	YFL029C	Cyclin-dependent kinase-activating kinase	genetic	1	1	1	Positive Genetic
MET14	YKL001C	Adenylylsulfate kinase	genetic	1	1	1	Negative Genetic
APC11	YDL008W	Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	1	1	1	Negative Genetic
IES3	YLR052W	Subunit of the INO80 chromatin remodeling complex	genetic	1	1	1	Negative Genetic
CSE4	YKL049C	Centromeric histone H3-like protein	physical	1	1	1	Affinity Capture-MS
APN1	YKL114C	Major apurinic/apyrimidinic endonuclease	genetic	1	1	1	Synthetic Lethality
CLC1	YGR167W	Clathrin light chain	genetic	1	1	1	Negative Genetic
DBF4	YDR052C	Regulatory subunit of Cdc7p-Dbf4p kinase complex	genetic	1	1	1	Negative Genetic
HOP1	YIL072W	Meiosis-specific protein required for chromosome synapsis	genetic	1	1	1	Negative Genetic
MCM3	YEL032W	Protein involved in DNA replication	genetic	1	1	1	Negative Genetic
MPS1	YDL028C	Dual-specificity kinase	genetic	1	1	1	Positive Genetic
FUS2	YMR232W	Cell fusion regulator	genetic	1	1	1	Negative Genetic
MPT5	YGL178W	mRNA-binding protein of the PUF family	physical	1	1	1	Affinity Capture-RNA
MCM7	YBR202W	Component of the Mcm2-7 hexameric helicase complex	physical	1	1	1	Affinity Capture-Western
ESC2	YDR363W	Sumo-like domain protein	genetic	1	1	1	Phenotypic Suppression
GPB2	YAL056W	Multistep regulator of cAMP-PKA signaling	genetic	1	1	1	Negative Genetic
DOT1	YDR440W	Nucleosomal histone H3-Lys79 methylase	genetic	1	1	1	Negative Genetic
CLA4	YNL298W	Cdc42p-activated signal transducing kinase	genetic	1	1	1	Synthetic Growth Defect
HHT2	YNL031C	Histone H3	physical	1	1	1	Affinity Capture-MS
KEX2	YNL238W	Kexin, a subtilisin-like protease (proprotein convertase)	genetic	1	1	1	Positive Genetic
ERV29	YGR284C	Protein localized to COPII-coated vesicles	genetic	1	1	1	Negative Genetic
MOG1	YJR074W	Conserved nuclear protein that interacts with GTP-Gsp1p	genetic	1	1	1	Positive Genetic
PRP9	YDL030W	Subunit of the SF3a splicing factor complex	physical	1	1	1	Two-hybrid
RPN3	YER021W	Essential non-ATPase regulatory subunit of the 26S proteasome lid	physical	1	1	1	Affinity Capture-MS
PSF2	YJL072C	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p)	physical	1	1	1	Affinity Capture-Western
SPT7	YBR081C	Subunit of the SAGA transcriptional regulatory complex	physical	1	1	1	Affinity Capture-MS
TAF9	YMR236W	Subunit (17 kDa) of TFIID and SAGA complexes	physical	1	1	1	Affinity Capture-MS
STB2	YMR053C	Protein that interacts with Sin3p in a two-hybrid assay	physical	1	1	1	Two-hybrid
TYE7	YOR344C	Serine-rich protein that contains a bHLH DNA binding motif	physical	1	1	1	Two-hybrid
SPT21	YMR179W	Protein with a role in transcriptional silencing	physical	1	1	1	Affinity Capture-MS
SPT21	YMR179W	Protein with a role in transcriptional silencing	genetic	1	1	1	Positive Genetic
VAM6	YDL077C	Guanine nucleotide exchange factor for the GTPase Gtr1p	physical	1	1	1	Affinity Capture-MS
RTT107	YHR154W	BRCA1 C-terminal domain protein needed for recovery from DNA damage	physical	1	1	1	Affinity Capture-Western
RSP5	YER125W	NEDD4 family E3 ubiquitin ligase	physical	1	1	1	Affinity Capture-MS
RSP5	YER125W	NEDD4 family E3 ubiquitin ligase	genetic	1	1	1	Negative Genetic
RPB3	YIL021W	RNA polymerase II third largest subunit B44	physical	1	1	1	Affinity Capture-MS
SSB1	YDL229W	Cytoplasmic ATPase that is a ribosome-associated molecular chaperone	physical	1	1	1	Affinity Capture-MS
SNF1	YDR477W	AMP-activated S/T protein kinase	genetic	1	1	1	Phenotypic Suppression
STE20	YHL007C	Cdc42p-activated signal transducing kinase	physical	1	1	1	Biochemical Activity
PHO85	YPL031C	Cyclin-dependent kinase	physical	1	1	1	Biochemical Activity
SAW1	YAL027W	5'- and 3'-flap DNA binding protein	physical	1	1	1	Affinity Capture-Western
TOP1	YOL006C	Topoisomerase I	physical	1	1	1	Affinity Capture-Western
RAD24	YER173W	Checkpoint protein	physical	1	1	1	Affinity Capture-Western
SEN1	YLR430W	ATP-dependent 5' to 3' RNA/DNA and DNA helicase	physical	1	1	1	Affinity Capture-Western
PCL1	YNL289W	Cyclin, interacts with cyclin-dependent kinase Pho85p	genetic	1	1	1	Dosage Rescue
ZRG8	YER033C	Protein of unknown function	genetic	1	1	1	Dosage Rescue
TAF14	YPL129W	Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes	genetic	1	1	1	Negative Genetic
SIN4	YNL236W	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
SPT4	YGR063C	Spt4p/5p (DSIF) transcription elongation factor complex subunit	genetic	1	1	1	Negative Genetic
RSC6	YCR052W	Component of the RSC chromatin remodeling complex	genetic	1	1	1	Negative Genetic
SGF73	YGL066W	Subunit of DUBm module of SAGA and SLIK	genetic	1	1	1	Negative Genetic
RPA43	YOR340C	RNA polymerase I subunit A43	genetic	1	1	1	Negative Genetic
SPT3	YDR392W	Subunit of the SAGA and SAGA-like transcriptional regulatory complexes	genetic	1	1	1	Negative Genetic
SUS1	YBR111W-A	Global transcriptional regulator, component of SAGA, TREX-2 complexes	genetic	1	1	1	Negative Genetic
SGV1	YPR161C	Cyclin (Bur2p)-dependent protein kinase	genetic	1	1	1	Negative Genetic
SDC1	YDR469W	Subunit of the COMPASS (Set1C) complex	genetic	1	1	1	Negative Genetic
RPC25	YKL144C	RNA polymerase III subunit C25	genetic	1	1	1	Negative Genetic
PFD1	YJL179W	Subunit of heterohexameric prefoldin	genetic	1	1	1	Positive Genetic
RGP1	YDR137W	Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p)	genetic	1	1	1	Positive Genetic
SIR4	YDR227W	SIR protein involved in assembly of silent chromatin domains	genetic	1	1	1	Synthetic Rescue
SIR3	YLR442C	Silencing protein	genetic	1	1	1	Synthetic Rescue
UBP3	YER151C	Ubiquitin-specific protease that cleaves Ub-protein fusions	genetic	1	1	1	Negative Genetic
RRD1	YIL153W	Peptidyl-prolyl cis/trans-isomerase	genetic	1	1	1	Negative Genetic
SPA2	YLL021W	Component of the polarisome	genetic	1	1	1	Positive Genetic
TUB3	YML124C	Alpha-tubulin	genetic	1	1	1	Negative Genetic
TEP1	YNL128W	PTEN homolog with no demonstrated inositol lipid phosphatase activity	genetic	1	1	1	Negative Genetic
POP4	YBR257W	Subunit of both RNase MRP and nuclear RNase P	genetic	1	1	1	Negative Genetic
RTC2	YBR147W	Putative vacuolar membrane transporter for cationic amino acids	genetic	1	1	1	Negative Genetic
RPL41A	YDL184C	Ribosomal 60S subunit protein L41A	genetic	1	1	1	Negative Genetic
RSC2	YLR357W	Component of the RSC chromatin remodeling complex	genetic	1	1	1	Negative Genetic
RRP1	YDR087C	Essential evolutionarily conserved nucleolar protein	genetic	1	1	1	Negative Genetic
SAC3	YDR159W	mRNA export factor	genetic	1	1	1	Negative Genetic
THG1	YGR024C	tRNAHis guanylyltransferase	genetic	1	1	1	Negative Genetic
RSM7	YJR113C	Mitochondrial ribosomal protein of the small subunit	genetic	1	1	1	Negative Genetic
YLR152C	YLR152C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
YCS4	YLR272C	Subunit of the condensin complex	genetic	1	1	1	Positive Genetic
RPS22B	YLR367W	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
PRP4	YPR178W	Splicing factor	genetic	1	1	1	Positive Genetic
PHO5	YBR093C	Repressible acid phosphatase	genetic	1	1	1	Synthetic Growth Defect
SOH1	YGL127C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Synthetic Growth Defect
RNR4	YGR180C	Ribonucleotide-diphosphate reductase (RNR) small subunit	genetic	1	1	1	Synthetic Growth Defect
SWI6	YLR182W	Transcription cofactor	genetic	1	1	1	Synthetic Lethality
MYO1	YHR023W	Type II myosin heavy chain	genetic	1	1	1	Synthetic Lethality
VMA21	YGR105W	Integral membrane protein required for V-ATPase function	genetic	1	1	1	Synthetic Growth Defect
VOA1	YGR106C	ER protein that functions in assembly of the V0 sector of V-ATPase	genetic	1	1	1	Synthetic Growth Defect
PSY2	YNL201C	Subunit of protein phosphatase PP4 complex	genetic	1	1	1	Synthetic Growth Defect
RTG3	YBL103C	bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways	genetic	1	1	1	Negative Genetic
SOK2	YMR016C	Nuclear protein that negatively regulates pseudohyphal differentiation	genetic	1	1	1	Negative Genetic
RAD61	YDR014W	Subunit of a complex that inhibits sister chromatid cohesion	genetic	1	1	1	Phenotypic Suppression
TTI1	YKL033W	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	1	1	1	Negative Genetic
TEL2	YGR099W	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	1	1	1	Negative Genetic
TPP1	YMR156C	DNA 3'-phosphatase	genetic	1	1	1	Synthetic Lethality
SMC6	YLR383W	Subunit of the SMC5-SMC6 complex	genetic	1	1	1	Synthetic Rescue
SWI1	YPL016W	Subunit of the SWI/SNF chromatin remodeling complex	genetic	1	1	1	Positive Genetic
NIP100	YPL174C	Large subunit of the dynactin complex	genetic	1	1	1	Positive Genetic
PDR1	YGL013C	Transcription factor that regulates the pleiotropic drug response	genetic	1	1	1	Positive Genetic
ROM2	YLR371W	Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p	genetic	1	1	1	Positive Genetic
YCK2	YNL154C	Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform	genetic	1	1	1	Positive Genetic
RPA49	YNL248C	RNA polymerase I subunit A49	genetic	1	1	1	Positive Genetic
STN1	YDR082W	Telomere end-binding and capping protein	genetic	1	1	1	Negative Genetic
PDS1	YDR113C	Securin	genetic	1	1	1	Negative Genetic
UBC1	YDR177W	Ubiquitin-conjugating enzyme	genetic	1	1	1	Negative Genetic
TRS23	YDR246W	Core component of transport protein particle (TRAPP) complexes I-III	genetic	1	1	1	Negative Genetic
NSE3	YDR288W	Component of the SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
SRB7	YDR308C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
NCB2	YDR397C	Subunit of a heterodimeric NC2 transcription regulator complex	genetic	1	1	1	Negative Genetic
UTP7	YER082C	Nucleolar protein	genetic	1	1	1	Negative Genetic
RAD3	YER171W	5' to 3' DNA helicase	genetic	1	1	1	Negative Genetic
NUP145	YGL092W	Essential protein with distinct roles in two nuclear pore subcomplexes	genetic	1	1	1	Negative Genetic
UTP8	YGR128C	Nucleolar protein required for export of tRNAs from the nucleus	genetic	1	1	1	Negative Genetic
YIP1	YGR172C	Integral membrane protein	genetic	1	1	1	Negative Genetic
RRN7	YJL025W	Component of the core factor (CF) rDNA transcription factor complex	genetic	1	1	1	Negative Genetic
RFA3	YJL173C	Subunit of heterotrimeric Replication Protein A (RPA)	genetic	1	1	1	Negative Genetic
RSC4	YKR008W	Component of the RSC chromatin remodeling complex	genetic	1	1	1	Negative Genetic
UTP21	YLR409C	Subunit of U3-containing 90S preribosome and SSU processome complexes	genetic	1	1	1	Negative Genetic
NSE5	YML023C	Component of the SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
NUP116	YMR047C	FG-nucleoporin component of central core of the nuclear pore complex	genetic	1	1	1	Negative Genetic
RAP1	YNL216W	Essential DNA-binding transcription regulator that binds many loci	genetic	1	1	1	Negative Genetic
RFC1	YOR217W	Subunit of heteropentameric Replication factor C (RF-C)	genetic	1	1	1	Negative Genetic
TAF3	YPL011C	TFIID subunit (47 kDa)	genetic	1	1	1	Negative Genetic
SMX3	YPR182W	Core Sm protein Sm F	genetic	1	1	1	Negative Genetic
PZF1	YPR186C	Transcription factor IIIA (TFIIIA)	genetic	1	1	1	Negative Genetic
STU1	YBL034C	Microtubule plus-end-tracking non-motor protein	genetic	1	1	1	Negative Genetic
TAF12	YDR145W	Subunit (61/68 kDa) of TFIID and SAGA complexes	genetic	1	1	1	Negative Genetic
SKI6	YGR195W	Exosome non-catalytic core component	genetic	1	1	1	Negative Genetic
NUP85	YJR042W	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
ORC1	YML065W	Largest subunit of the origin recognition complex	genetic	1	1	1	Negative Genetic
SEC12	YNR026C	Guanine nucleotide exchange factor (GEF)	genetic	1	1	1	Negative Genetic
TOA1	YOR194C	TFIIA large subunit	genetic	1	1	1	Negative Genetic
YBL081W	YBL081W	Non-essential protein of unknown function	genetic	1	1	1	Negative Genetic
UBS1	YBR165W	Ubiquitin-conjugating enzyme suppressor that regulates Cdc34p	genetic	1	1	1	Negative Genetic
VMS1	YDR049W	Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes,	genetic	1	1	1	Negative Genetic
RAD55	YDR076W	Protein that stimulates strand exchange	genetic	1	1	1	Negative Genetic
SED1	YDR077W	Major stress-induced structural GPI-cell wall glycoprotein	genetic	1	1	1	Negative Genetic
SWF1	YDR126W	Palmitoyltransferase that acts on transmembrane proteins	genetic	1	1	1	Negative Genetic
SWI5	YDR146C	Transcription factor that recruits Mediator and Swi/Snf complexes	genetic	1	1	1	Negative Genetic
SAS4	YDR181C	Subunit of the SAS complex (Sas2p, Sas4p, Sas5p)	genetic	1	1	1	Negative Genetic
SND1	YDR186C	Protein involved in SRP-independent targeting of substrates to the ER	genetic	1	1	1	Negative Genetic
REF2	YDR195W	RNA-binding protein	genetic	1	1	1	Negative Genetic
OMS1	YDR316W	Protein integral to the mitochondrial membrane	genetic	1	1	1	Negative Genetic
YGL235W	YGL235W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
RSM27	YGR215W	Mitochondrial ribosomal protein of the small subunit	genetic	1	1	1	Negative Genetic
TNA1	YGR260W	High affinity nicotinic acid plasma membrane permease	genetic	1	1	1	Negative Genetic
YHR050W-A	YHR050W-A	Protein of unknown function	genetic	1	1	1	Negative Genetic
SEC28	YIL076W	Epsilon-COP subunit of the coatomer	genetic	1	1	1	Negative Genetic
NUC1	YJL208C	Major mitochondrial nuclease	genetic	1	1	1	Negative Genetic
RSM26	YJR101W	Mitochondrial ribosomal protein of the small subunit	genetic	1	1	1	Negative Genetic
PTR2	YKR093W	Integral membrane peptide transporter	genetic	1	1	1	Negative Genetic
SMA2	YML066C	Meiosis-specific prospore membrane protein	genetic	1	1	1	Negative Genetic
SUB1	YMR039C	Transcriptional regulator	genetic	1	1	1	Negative Genetic
VAC7	YNL054W	Integral vacuolar membrane protein	genetic	1	1	1	Negative Genetic
POR1	YNL055C	Mitochondrial porin (voltage-dependent anion channel)	genetic	1	1	1	Negative Genetic
YTP1	YNL237W	Probable type-III integral membrane protein of unknown function	genetic	1	1	1	Negative Genetic
SNF12	YNR023W	73 kDa subunit of the SWI/SNF chromatin remodeling complex	genetic	1	1	1	Negative Genetic
YKU80	YMR106C	Subunit of telomeric Ku complex (Yku70p-Yku80p)	genetic	1	1	1	Phenotypic Enhancement
YNR068C	YNR068C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
WSC3	YOL105C	Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway	genetic	1	1	1	Negative Genetic
YOL162W	YOL162W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
SUR1	YPL057C	Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit	genetic	1	1	1	Negative Genetic
UBP12	YJL197W	Ubiquitin-specific protease	genetic	1	1	1	Negative Genetic
XRN1	YGL173C	Evolutionarily-conserved 5'-3' exonuclease	genetic	1	1	1	Negative Genetic
RAD57	YDR004W	Protein that stimulates strand exchange	genetic	1	1	1	Negative Genetic
RPL11A	YPR102C	Ribosomal 60S subunit protein L11A	genetic	1	1	1	Positive Genetic
MSH1	YHR120W	DNA-binding protein of the mitochondria	genetic	1	1	1	Positive Genetic
RPS10B	YMR230W	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Positive Genetic
UBP7	YIL156W	Ubiquitin-specific protease that cleaves ubiquitin-protein fusions	genetic	1	1	1	Synthetic Growth Defect
VTC1	YER072W	Regulatory subunit of the vacuolar transporter chaperone (VTC) complex	genetic	1	1	1	Negative Genetic
TDP1	YBR223C	Tyrosyl-DNA phosphodiesterase I	genetic	1	1	1	Synthetic Growth Defect
STB4	YMR019W	Putative transcription factor	genetic	1	1	1	Negative Genetic
SPC24	YMR117C	Component of the kinetochore-associated Ndc80 complex	genetic	1	1	1	Positive Genetic
RIM20	YOR275C	Protein involved in proteolytic activation of Rim101p	genetic	1	1	1	Negative Genetic
YKE2	YLR200W	Subunit of the heterohexameric Gim/prefoldin protein complex	genetic	1	1	1	Negative Genetic
PML39	YML107C	Protein required for nuclear retention of unspliced pre-mRNAs	genetic	1	1	1	Negative Genetic
RET2	YFR051C	Delta subunit of the coatomer complex (COPI)	genetic	1	1	1	Negative Genetic
MSN2	YMR037C	Stress-responsive transcriptional activator	genetic	1	1	1	Phenotypic Suppression
MSN4	YKL062W	Stress-responsive transcriptional activator	genetic	1	1	1	Phenotypic Suppression
PMA1	YGL008C	Plasma membrane P2-type H+-ATPase	genetic	1	1	1	Negative Genetic
TEN1	YLR010C	Protein that regulates telomeric length	genetic	1	1	1	Synthetic Growth Defect
SET1	YHR119W	Histone methyltransferase, subunit of the COMPASS (Set1C) complex	genetic	1	1	1	Synthetic Rescue
BUG1	YDL099W	Cis-golgi localized protein involved in ER to Golgi transport	genetic	1	1	1	Negative Genetic
HNM1	YGL077C	Plasma membrane transporter for choline, ethanolamine, and carnitine	genetic	1	1	1	Negative Genetic
JHD2	YJR119C	JmjC domain family histone demethylase	genetic	1	1	1	Negative Genetic
KCS1	YDR017C	Inositol hexakisphosphate and inositol heptakisphosphate kinase	genetic	1	1	1	Negative Genetic
ETR1	YBR026C	2-enoyl thioester reductase	genetic	1	1	1	Negative Genetic
LIP5	YOR196C	Protein involved in biosynthesis of the coenzyme lipoic acid	genetic	1	1	1	Negative Genetic
ACL4	YDR161W	Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b	genetic	1	1	1	Negative Genetic
ARO2	YGL148W	Bifunctional chorismate synthase and flavin reductase	genetic	1	1	1	Negative Genetic
APJ1	YNL077W	Hsp40 chaperone with a role in SUMO-mediated protein degradation	physical	1	1	1	Affinity Capture-MS
CMK2	YOL016C	Calmodulin-dependent protein kinase	physical	1	1	1	Reconstituted Complex
ARV1	YLR242C	Cortical ER protein	genetic	1	1	1	Positive Genetic
IRC5	YFR038W	Putative ATPase containing the DEAD/H helicase-related sequence motif	genetic	1	1	1	Synthetic Growth Defect
DGR2	YKL121W	Protein of unknown function	genetic	1	1	1	Negative Genetic
MDM34	YGL219C	Mitochondrial component of the ERMES complex	genetic	1	1	1	Positive Genetic
MDM32	YOR147W	Mitochondrial inner membrane protein with similarity to Mdm31p	genetic	1	1	1	Negative Genetic
ERG3	YLR056W	C-5 sterol desaturase	genetic	1	1	1	Negative Genetic
DAL2	YIR029W	Allantoicase	genetic	1	1	1	Negative Genetic
ISC1	YER019W	Inositol phosphosphingolipid phospholipase C	genetic	1	1	1	Synthetic Growth Defect
GCG1	YER163C	Gamma-glutamyl cyclotransferase	genetic	1	1	1	Negative Genetic
CLB6	YGR109C	B-type cyclin involved in DNA replication during S phase	genetic	1	1	1	Positive Genetic
IFM1	YOL023W	Mitochondrial translation initiation factor 2	genetic	1	1	1	Positive Genetic
CDC1	YDR182W	Putative mannose-ethanolamine phosphate phosphodiesterase	genetic	1	1	1	Positive Genetic
MMM1	YLL006W	ER integral membrane protein, ERMES complex subunit	genetic	1	1	1	Positive Genetic
IRC21	YMR073C	Protein of unknown function	genetic	1	1	1	Negative Genetic
MME1	YMR166C	Transporter of the mitochondrial inner membrane that exports magnesium	genetic	1	1	1	Negative Genetic
ECM23	YPL021W	Non-essential protein of unconfirmed function	genetic	1	1	1	Negative Genetic