Standard name Systematic name Name description Description
CSE4 YKL049C Centromeric histone H3-like protein Centromeric histone H3-like protein; associates with promoters, accessible chromatin, and RNAPII-bound regions; Cse4p associates with centromeres, promoting kinetochore assembly and Sgo1p association with centromeric chromatin; Ipl1p-dependent phosphorylation destabilizes defective kinetochores promoting bi-orientation; phosphorylation by Cdc7p maintains Cse4p at kinetochores and promotes faithful chromosome segregation; regulated by multiple E3 ligases; complements human homolog CENPA mutations
Visualize the interactome of CSE4
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 88

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.057 NaN NaN
Budsite 0.086 NaN 0.057
Cytoplasm 0.086 NaN 0.138
Endosome 0.200 NaN NaN
Mito 0.200 NaN 0.494
Nucleolus 0.400 NaN 0.207
Nucleus 0.086 NaN NaN
Peroxisome 0.086 NaN NaN
SpindlePole 0.200 NaN 0.368
Vac/Vac Memb 0.086 NaN NaN

GFP localization & abundance

GFP localization GFP abundance
nucleus, spindle pole no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CSE4 0 1 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p physical 15 4 9 Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Affinity Capture-MS, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
SCM3 YDL139C Nonhistone component of centromeric chromatin physical 14 4 12 Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Co-localization, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p genetic 13 8 10 Dosage Growth Defect, Dosage Rescue, Dosage Lethality, Dosage Lethality, Dosage Lethality, Synthetic Growth Defect, Synthetic Lethality, Phenotypic Suppression, Synthetic Rescue, Dosage Rescue, Negative Genetic, Dosage Growth Defect, Dosage Lethality
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 12 3 10 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation physical 10 6 6 Affinity Capture-Western, Co-localization, Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Protein-peptide, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 9 5 8 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue, Phenotypic Suppression, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic
HHF1 YBR009C Histone H4 physical 9 5 8 Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Co-crystal Structure, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs physical 9 4 7 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Protein-peptide, Reconstituted Complex
MIF2 YKL089W Centromeric CDEIII region binding protein physical 7 4 6 Affinity Capture-MS, Affinity Capture-Western, Co-localization, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
HHF1 YBR009C Histone H4 genetic 7 4 6 Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Lethality, Negative Genetic, Synthetic Growth Defect
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 7 3 6 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
CSE4 YKL049C Centromeric histone H3-like protein physical 6 4 6 Affinity Capture-Western, Affinity Capture-MS, FRET, PCA, Affinity Capture-Western, Affinity Capture-MS
SCM3 YDL139C Nonhistone component of centromeric chromatin genetic 6 2 6 Dosage Rescue, Dosage Rescue, Dosage Rescue, Phenotypic Suppression, Dosage Rescue, Dosage Rescue
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 6 4 5 Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Negative Genetic
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs genetic 6 5 4 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Synthetic Lethality, Synthetic Rescue, Phenotypic Suppression
HTA1 YDR225W Histone H2A physical 6 2 4 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 5 4 4 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Suppression
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation physical 4 3 4 Two-hybrid, Two-hybrid, Co-localization, Affinity Capture-MS
HHF2 YNL030W Histone H4 physical 4 3 4 Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 4 3 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity
HTA1 YDR225W Histone H2A genetic 4 3 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue, Negative Genetic
HHT1 YBR010W Histone H3 genetic 4 3 3 Dosage Lethality, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 4 3 3 Synthetic Growth Defect, Negative Genetic, Synthetic Rescue, Synthetic Growth Defect
HTA2 YBL003C Histone H2A physical 4 2 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
HTB1 YDR224C Histone H2B physical 4 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex physical 4 1 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
SGO1 YOR073W Component of the spindle checkpoint physical 4 3 2 Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Reconstituted Complex
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 3 3 3 Synthetic Growth Defect, Synthetic Lethality, Negative Genetic
HHF2 YNL030W Histone H4 genetic 3 3 3 Synthetic Growth Defect, Negative Genetic, Positive Genetic
CTF3 YLR381W Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p genetic 3 3 3 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 3 3 3 Dosage Lethality, Synthetic Growth Defect, Negative Genetic
MTW1 YAL034W-A Essential component of the MIND kinetochore complex physical 3 2 3 Affinity Capture-Western, Affinity Capture-Western, Co-localization
HTB2 YBL002W Histone H2B physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
HIR1 YBL008W Subunit of the HIR complex genetic 3 3 2 Synthetic Growth Defect, Dosage Lethality, Negative Genetic
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
HHT1 YBR010W Histone H3 physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
HHT2 YNL031C Histone H3 physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 3 1 2 Dosage Lethality, Dosage Lethality, Dosage Lethality
CDC5 YMR001C Polo-like kinase required for mitotic exit regulation 3 3 1 co-immunoprecipitation evidence, protein kinase assay evidence, qualitative western immunoblotting evidence
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) physical 2 2 2 Reconstituted Complex, Co-localization
SNF1 YDR477W AMP-activated S/T protein kinase physical 2 2 2 Affinity Capture-MS, Two-hybrid
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase physical 2 2 2 Affinity Capture-MS, Two-hybrid
SMC3 YJL074C Subunit of the multiprotein cohesin complex physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
MCM22 YJR135C Outer kinetochore protein and component of the Ctf3 subcomplex genetic 2 2 2 Synthetic Lethality, Negative Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 2 2 2 Synthetic Rescue, Negative Genetic
IML3 YBR107C Outer kinetochore protein and component of the Ctf19 complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
UBX7 YBR273C UBX (ubiquitin regulatory X) domain-containing protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 2 2 Synthetic Lethality, Negative Genetic
CBF2 YGR140W Essential kinetochore protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 2 2 Dosage Growth Defect, Positive Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
NNF1 YJR112W Essential component of the outer kinetochore MIND complex physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 2 1 2 Positive Genetic, Positive Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 2 1 2 Negative Genetic, Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 2 1 2 Negative Genetic, Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 2 1 2 Negative Genetic, Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 2 1 2 Negative Genetic, Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions regulation 2 2 1 co-immunoprecipitation evidence, qualitative western immunoblotting evidence
MET30 YIL046W F-box protein containing five copies of the WD40 motif regulation 2 2 1 co-immunoprecipitation evidence, qualitative western immunoblotting evidence
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex regulation 2 2 1 co-immunoprecipitation evidence, qualitative western immunoblotting evidence
ASF1 YJL115W Nucleosome assembly factor genetic 2 2 1 Dosage Lethality, Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 2 2 1 Synthetic Growth Defect, Dosage Growth Defect
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 2 2 1 Dosage Rescue, Synthetic Rescue
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 2 2 1 Synthetic Rescue, Dosage Lethality
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 2 2 1 Dosage Lethality, Negative Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 2 2 1 Dosage Lethality, Negative Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 2 2 1 Dosage Lethality, Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 2 2 1 Synthetic Growth Defect, Dosage Growth Defect
CDC53 YDL132W Cullin physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) regulation 1 1 1 protein kinase assay evidence
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p regulation 1 1 1 qualitative western immunoblotting evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription physical 1 1 1 Affinity Capture-MS
CHL4 YDR254W Outer kinetochore protein required for chromosome stability physical 1 1 1 Co-localization
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
BFR2 YDR299W Component of the SSU and 90S preribosomes physical 1 1 1 Affinity Capture-MS
ADH1 YOL086C Alcohol dehydrogenase physical 1 1 1 Affinity Capture-MS
BMH1 YER177W 14-3-3 protein, major isoform physical 1 1 1 Affinity Capture-MS
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 1 1 1 Affinity Capture-MS
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Positive Genetic
CEX1 YOR112W Component of nuclear aminoacylation-dependent tRNA export pathway physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex physical 1 1 1 Affinity Capture-MS
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Affinity Capture-MS
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme physical 1 1 1 Affinity Capture-MS
APL1 YJR005W Beta-adaptin genetic 1 1 1 Negative Genetic
ARO1 YDR127W Pentafunctional arom protein physical 1 1 1 Affinity Capture-MS
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Synthetic Lethality
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Lethality
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Positive Genetic
CHC1 YGL206C Clathrin heavy chain physical 1 1 1 Affinity Capture-MS
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex physical 1 1 1 Affinity Capture-MS
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Synthetic Growth Defect
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family physical 1 1 1 Affinity Capture-MS
ADA2 YDR448W Transcription coactivator genetic 1 1 1 Negative Genetic
BUD3 YCL014W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin genetic 1 1 1 Synthetic Growth Defect
BLM10 YFL007W Proteasome activator physical 1 1 1 Affinity Capture-MS
BLM10 YFL007W Proteasome activator genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Positive Genetic
CRN1 YLR429W Coronin genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT7 YJL111W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-MS
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 1 1 1 Affinity Capture-MS
ACH1 YBL015W Protein with CoA transferase activity genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex genetic 1 1 1 Positive Genetic
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization genetic 1 1 1 Positive Genetic
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator genetic 1 1 1 Positive Genetic
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Positive Genetic
BUB2 YMR055C Mitotic exit network regulator genetic 1 1 1 Negative Genetic
CMP2 YML057W Calcineurin A genetic 1 1 1 Positive Genetic
BUD13 YGL174W Subunit of the RES complex genetic 1 1 1 Positive Genetic
CMK1 YFR014C Calmodulin-dependent protein kinase genetic 1 1 1 Negative Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
ADD66 YKL206C Protein involved in 20S proteasome assembly genetic 1 1 1 Negative Genetic
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Synthetic Lethality
CBP3 YPL215W Mitochondrial protein required for assembly of cytochrome bc1 complex physical 1 1 1 Affinity Capture-MS
ARE1 YCR048W Acyl-CoA:sterol acyltransferase genetic 1 1 1 Positive Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p physical 1 1 1 Affinity Capture-Western
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Negative Genetic
APA1 YCL050C AP4A phosphorylase genetic 1 1 1 Positive Genetic
BTN2 YGR142W v-SNARE binding protein physical 1 1 1 Affinity Capture-MS
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Synthetic Growth Defect
ATG5 YPL149W Conserved protein involved in autophagy and the Cvt pathway genetic 1 1 1 Positive Genetic
CNM1 YBR063C Molecular tether on nuclear membrane genetic 1 1 1 Negative Genetic
CRC1 YOR100C Mitochondrial inner membrane carnitine transporter genetic 1 1 1 Negative Genetic
APL4 YPR029C Gamma-adaptin genetic 1 1 1 Negative Genetic
ASI3 YNL008C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Positive Genetic
ADE8 YDR408C Phosphoribosyl-glycinamide transformylase genetic 1 1 1 Positive Genetic
CIN4 YMR138W GTP-binding protein involved in beta-tubulin (Tub2p) folding genetic 1 1 1 Positive Genetic
CIT2 YCR005C Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle genetic 1 1 1 Positive Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Synthetic Growth Defect
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase physical 1 1 1 Affinity Capture-MS
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Synthetic Growth Defect
CLG1 YGL215W Cyclin-like protein that interacts with Pho85p genetic 1 1 1 Negative Genetic
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation genetic 1 1 1 Positive Genetic
BMT2 YBR141C Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
CNL1 YDR357C Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Positive Genetic
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 Co-localization
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Positive Genetic
APC9 YLR102C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Positive Genetic
BMT5 YIL096C Methyltransferase required for m3U2634 methylation of the 25S rRNA genetic 1 1 1 Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Negative Genetic
MTW1 YAL034W-A Essential component of the MIND kinetochore complex genetic 1 1 1 Synthetic Growth Defect
NSL1 YPL233W Essential component of the MIND kinetochore complex physical 1 1 1 Affinity Capture-Western
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Co-localization
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Synthetic Rescue
PRP9 YDL030W Subunit of the SF3a splicing factor complex physical 1 1 1 Two-hybrid
YBP2 YGL060W Central kinetochore associated protein physical 1 1 1 Affinity Capture-Western
HTA2 YBL003C Histone H2A genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase physical 1 1 1 Affinity Capture-MS
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase physical 1 1 1 Affinity Capture-MS
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 1 1 1 Affinity Capture-MS
HSP60 YLR259C Tetradecameric mitochondrial chaperonin physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
YER138C YER138C Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
YDR316W-B YDR316W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
FAS1 YKL182W Beta subunit of fatty acid synthetase physical 1 1 1 Affinity Capture-MS
YDR261C-D YDR261C-D Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YDR365W-B YDR365W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YGR027W-B YGR027W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YDR210C-D YDR210C-D Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YGR038C-B YGR038C-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YER160C YER160C Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YDR098C-B YDR098C-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
YHR214C-B YHR214C-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YJR029W YJR029W Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YJR027W YJR027W Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YDJ1 YNL064C Type I HSP40 co-chaperone physical 1 1 1 Affinity Capture-MS
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 1 1 1 Affinity Capture-MS
YGR161C-D YGR161C-D Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YML045W YML045W Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
SPT6 YGR116W Nucleosome remodeling protein physical 1 1 1 Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Affinity Capture-MS
NMD5 YJR132W Karyopherin physical 1 1 1 Affinity Capture-MS
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 1 1 1 Affinity Capture-MS
SSE2 YBR169C Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family physical 1 1 1 Affinity Capture-MS
NEW1 YPL226W Translation termination and ribosome biogenesis factor physical 1 1 1 Affinity Capture-MS
RPB2 YOR151C RNA polymerase II second largest subunit B150 physical 1 1 1 Affinity Capture-MS
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
NUM1 YDR150W Protein required for nuclear migration physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-MS
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
MDJ1 YFL016C Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity physical 1 1 1 Affinity Capture-MS
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
KAP123 YER110C Karyopherin beta physical 1 1 1 Affinity Capture-MS
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer physical 1 1 1 Affinity Capture-MS
IKI3 YLR384C Subunit of Elongator complex physical 1 1 1 Affinity Capture-MS
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
TUB1 YML085C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
STT4 YLR305C Phosphatidylinositol-4-kinase physical 1 1 1 Affinity Capture-MS
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
HAT2 YEL056W Subunit of the Hat1p-Hat2p histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
TUB3 YML124C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
YDR261C-C YDR261C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YAR010C YAR010C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YPR137C-A YPR137C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YPR137C-B YPR137C-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex physical 1 1 1 Affinity Capture-MS
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
SEC21 YNL287W Gamma subunit of coatomer physical 1 1 1 Affinity Capture-MS
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering physical 1 1 1 Affinity Capture-MS
TUB2 YFL037W Beta-tubulin physical 1 1 1 Affinity Capture-MS
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-MS
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
LEU1 YGL009C Isopropylmalate isomerase physical 1 1 1 Affinity Capture-MS
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 physical 1 1 1 Affinity Capture-MS
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 genetic 1 1 1 Negative Genetic
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 physical 1 1 1 Affinity Capture-MS
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis physical 1 1 1 Affinity Capture-MS
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases physical 1 1 1 Affinity Capture-MS
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases genetic 1 1 1 Positive Genetic
YDR210W-B YDR210W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
PIL1 YGR086C Eisosome core component physical 1 1 1 Affinity Capture-MS
PIL1 YGR086C Eisosome core component genetic 1 1 1 Positive Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
PDI1 YCL043C Protein disulfide isomerase physical 1 1 1 Affinity Capture-MS
MTC1 YJL123C Protein of unknown function that may interact with ribosomes physical 1 1 1 Affinity Capture-MS
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Positive Genetic
EFR3 YMR212C Protein required for Stt4-containing PI kinase complex localization physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-MS
SEC13 YLR208W Structural component of 3 complexes physical 1 1 1 Affinity Capture-MS
YHB1 YGR234W Nitric oxide oxidoreductase physical 1 1 1 Affinity Capture-MS
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
SCJ1 YMR214W One of several homologs of bacterial chaperone DnaJ physical 1 1 1 Affinity Capture-MS
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes physical 1 1 1 Affinity Capture-MS
TCB1 YOR086C Lipid-binding ER protein involved in ER-plasma membrane tethering physical 1 1 1 Affinity Capture-MS
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Affinity Capture-MS
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring physical 1 1 1 Affinity Capture-MS
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase physical 1 1 1 Affinity Capture-MS
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Positive Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes physical 1 1 1 Affinity Capture-MS
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase physical 1 1 1 Affinity Capture-MS
EIS1 YMR031C Component of the eisosome required for proper eisosome assembly physical 1 1 1 Affinity Capture-MS
SYP1 YCR030C Negative regulator of WASP-Arp23 complex physical 1 1 1 Affinity Capture-MS
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
MPM1 YJL066C Mitochondrial intermembrane space protein of unknown function physical 1 1 1 Affinity Capture-MS
HIF1 YLL022C Non-essential component of the HAT-B histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
NCP1 YHR042W NADP-cytochrome P450 reductase physical 1 1 1 Affinity Capture-MS
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter physical 1 1 1 Affinity Capture-MS
VTC5 YDR089W Novel subunit of the vacuolar transporter chaperone complex physical 1 1 1 Affinity Capture-MS
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
VID27 YNL212W Cytoplasmic protein of unknown function physical 1 1 1 Affinity Capture-MS
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
YNL054W-B YNL054W-B TyB Gag-Pol protein physical 1 1 1 Affinity Capture-MS
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) physical 1 1 1 Affinity Capture-MS
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
SRV2 YNL138W CAP (cyclase-associated protein) physical 1 1 1 Affinity Capture-MS
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis physical 1 1 1 Affinity Capture-MS
SIR3 YLR442C Silencing protein physical 1 1 1 Affinity Capture-MS
NVJ2 YPR091C Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) physical 1 1 1 Affinity Capture-MS
STE20 YHL007C Cdc42p-activated signal transducing kinase physical 1 1 1 Affinity Capture-MS
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
YNR065C YNR065C Protein of unknown function physical 1 1 1 Affinity Capture-MS
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen physical 1 1 1 Affinity Capture-MS
SXM1 YDR395W Nuclear transport factor (karyopherin) physical 1 1 1 Affinity Capture-MS
PAA1 YDR071C Polyamine acetyltransferase physical 1 1 1 Affinity Capture-MS
PAA1 YDR071C Polyamine acetyltransferase genetic 1 1 1 Negative Genetic
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation physical 1 1 1 Affinity Capture-MS
YNR066C YNR066C Putative membrane-localized protein of unknown function physical 1 1 1 Affinity Capture-MS
NPL6 YMR091C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-MS
NPL3 YDR432W RNA-binding protein physical 1 1 1 Affinity Capture-MS
TCM62 YBR044C Protein involved in assembly of the succinate dehydrogenase complex physical 1 1 1 Affinity Capture-MS
TCM62 YBR044C Protein involved in assembly of the succinate dehydrogenase complex genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer physical 1 1 1 Affinity Capture-MS
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B physical 1 1 1 Affinity Capture-MS
SEC63 YOR254C Essential subunit of Sec63 complex physical 1 1 1 Affinity Capture-MS
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex physical 1 1 1 Affinity Capture-MS
VPS5 YOR069W Nexin-1 homolog physical 1 1 1 Affinity Capture-MS
EDC3 YEL015W Non-essential conserved protein with a role in mRNA decapping physical 1 1 1 Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex physical 1 1 1 Affinity Capture-MS
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
FAA4 YMR246W Long chain fatty acyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
MDV1 YJL112W Peripheral protein of cytosolic face of mitochondrial outer membrane physical 1 1 1 Affinity Capture-MS
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane physical 1 1 1 Affinity Capture-MS
YPP1 YGR198W Cargo-transport protein involved in endocytosis physical 1 1 1 Affinity Capture-MS
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
HMG1 YML075C HMG-CoA reductase physical 1 1 1 Affinity Capture-MS
HMG1 YML075C HMG-CoA reductase genetic 1 1 1 Positive Genetic
RPN2 YIL075C Subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
NAB6 YML117W Putative RNA-binding protein physical 1 1 1 Affinity Capture-MS
SEC3 YER008C Subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase genetic 1 1 1 Positive Genetic
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation physical 1 1 1 Affinity Capture-MS
INO80 YGL150C Nucleosome spacing factor physical 1 1 1 Affinity Capture-MS
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase physical 1 1 1 Affinity Capture-MS
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway physical 1 1 1 Affinity Capture-MS
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
TSA1 YML028W Thioredoxin peroxidase physical 1 1 1 Affinity Capture-MS
VPS75 YNL246W NAP family histone chaperone physical 1 1 1 Affinity Capture-MS
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism physical 1 1 1 Affinity Capture-MS
RFC3 YNL290W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 1 1 1 Affinity Capture-MS
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 1 1 1 Affinity Capture-MS
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
MCM21 YDR318W Component of the kinetochore sub-complex COMA physical 1 1 1 Affinity Capture-MS
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
YBL111C YBL111C Helicase-like protein encoded within the telomeric Y' element physical 1 1 1 Affinity Capture-MS
NOG2 YNR053C Putative GTPase physical 1 1 1 Affinity Capture-MS
SMY2 YBR172C GYF domain protein physical 1 1 1 Affinity Capture-MS
YME1 YPR024W Catalytic subunit of i-AAA protease complex physical 1 1 1 Affinity Capture-MS
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
KAP95 YLR347C Karyopherin beta physical 1 1 1 Affinity Capture-MS
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex physical 1 1 1 Affinity Capture-MS
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex physical 1 1 1 Affinity Capture-MS
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Affinity Capture-MS
MCM2 YBL023C Protein involved in DNA replication physical 1 1 1 Affinity Capture-MS
FUN12 YAL035W Translation initiation factor eIF5B physical 1 1 1 Affinity Capture-MS
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 1 1 1 Affinity Capture-MS
MRC1 YCL061C S-phase checkpoint protein required for DNA replication physical 1 1 1 Affinity Capture-MS
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex physical 1 1 1 Affinity Capture-MS
YML133C YML133C Putative Y' element ATP-dependent helicase physical 1 1 1 Affinity Capture-MS
YIL177C YIL177C Putative Y' element ATP-dependent helicase physical 1 1 1 Affinity Capture-MS
PHO81 YGR233C Cyclin-dependent kinase (CDK) inhibitor physical 1 1 1 Affinity Capture-MS
YJL225C YJL225C Putative Y' element ATP-dependent helicase physical 1 1 1 Affinity Capture-MS
YRF1-6 YNL339C Helicase encoded by the Y' element of subtelomeric regions physical 1 1 1 Affinity Capture-MS
VTH1 YIL173W Putative membrane glycoprotein physical 1 1 1 Affinity Capture-MS
VTH1 YIL173W Putative membrane glycoprotein genetic 1 1 1 Negative Genetic
VTH2 YJL222W Putative membrane glycoprotein physical 1 1 1 Affinity Capture-MS
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) physical 1 1 1 Affinity Capture-MS
PUP3 YER094C Beta 3 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
SAR1 YPL218W ARF family GTPase physical 1 1 1 Affinity Capture-MS
PLN1 YKR046C Perilipin, involved in formation and stability of lipid droplets physical 1 1 1 Affinity Capture-MS
PRE5 YMR314W Alpha 6 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
NKP1 YDR383C Central kinetochore protein and subunit of the Ctf19 complex physical 1 1 1 Affinity Capture-MS
NKP1 YDR383C Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Negative Genetic
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
TIF35 YDR429C eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
PRE4 YFR050C Beta 7 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex physical 1 1 1 Affinity Capture-MS
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Positive Genetic
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex physical 1 1 1 Affinity Capture-MS
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex physical 1 1 1 Affinity Capture-MS
TIM50 YPL063W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
TAF4 YMR005W TFIID subunit (48 kDa) physical 1 1 1 Affinity Capture-MS
UTP9 YHR196W Nucleolar protein physical 1 1 1 Affinity Capture-MS
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs physical 1 1 1 Affinity Capture-MS
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
HRK1 YOR267C Protein kinase physical 1 1 1 Affinity Capture-MS
RIE1 YGR250C RNA binding protein and negative regulator of START physical 1 1 1 Affinity Capture-MS
ELP3 YPL086C Subunit of Elongator complex physical 1 1 1 Affinity Capture-MS
RSC6 YCR052W Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
HPR1 YDR138W Subunit of THO/TREX complexes physical 1 1 1 Affinity Capture-MS
NAN1 YPL126W U3 snoRNP protein physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
RSC2 YLR357W Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
MCM6 YGL201C Protein involved in DNA replication physical 1 1 1 Affinity Capture-MS
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex physical 1 1 1 Affinity Capture-MS
CTF4 YPR135W Chromatin-associated protein physical 1 1 1 Affinity Capture-MS
SLA1 YBL007C Cytoskeletal protein binding protein physical 1 1 1 Affinity Capture-MS
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping physical 1 1 1 Affinity Capture-MS
UBP2 YOR124C Ubiquitin-specific protease physical 1 1 1 Affinity Capture-MS
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 1 1 1 Affinity Capture-MS
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
OSH2 YDL019C Member of an oxysterol-binding protein family with seven members physical 1 1 1 Affinity Capture-MS
RPO31 YOR116C RNA polymerase III largest subunit C160 physical 1 1 1 Affinity Capture-MS
TCB2 YNL087W ER protein involved in ER-plasma membrane tethering physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
TOP2 YNL088W Topoisomerase II physical 1 1 1 Affinity Capture-MS
MYO1 YHR023W Type II myosin heavy chain physical 1 1 1 Affinity Capture-MS
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors physical 1 1 1 Affinity Capture-MS
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis physical 1 1 1 Affinity Capture-MS
YRF1-1 YDR545W Helicase encoded by the Y' element of subtelomeric regions physical 1 1 1 Affinity Capture-MS
YRF1-5 YLR467W Helicase encoded by the Y' element of subtelomeric regions physical 1 1 1 Affinity Capture-MS
YRF1-7 YPL283C Helicase encoded by the Y' element of subtelomeric regions physical 1 1 1 Affinity Capture-MS
YRF1-3 YGR296W Helicase encoded by the Y' element of subtelomeric regions physical 1 1 1 Affinity Capture-MS
IPL1 YPL209C Aurora kinase of chromosomal passenger complex physical 1 1 1 Biochemical Activity
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-Western
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Synthetic Growth Defect
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex physical 1 1 1 Affinity Capture-Western
SIZ1 YDR409W SUMO E3 ligase physical 1 1 1 Biochemical Activity
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Positive Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HIR2 YOR038C Subunit of HIR nucleosome assembly complex physical 1 1 1 Affinity Capture-Western
MCM10 YIL150C Essential chromatin-associated protein physical 1 1 1 Two-hybrid
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A physical 1 1 1 Two-hybrid
TAT2 YOL020W High affinity tryptophan and tyrosine permease physical 1 1 1 Two-hybrid
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex physical 1 1 1 Two-hybrid
SPS1 YDR523C STE20-family GCKIII protein kinase physical 1 1 1 Two-hybrid
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 1 1 1 Affinity Capture-Western
CTF13 YMR094W Subunit of the CBF3 complex physical 1 1 1 Reconstituted Complex
SFH1 YLR321C Component of the RSC chromatin remodeling complex genetic 1 1 1 Dosage Rescue
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 1 1 1 Synthetic Growth Defect
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p genetic 1 1 1 Synthetic Growth Defect
STB5 YHR178W Transcription factor genetic 1 1 1 Synthetic Growth Defect
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Synthetic Growth Defect
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex genetic 1 1 1 Dosage Lethality
SAS4 YDR181C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 1 1 1 Dosage Lethality
SAS5 YOR213C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 1 1 1 Dosage Lethality
FUN30 YAL019W Snf2p family member with ATP-dependent chromatin remodeling activity genetic 1 1 1 Synthetic Growth Defect
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Synthetic Growth Defect
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Dosage Growth Defect
PEP3 YLR148W Component of CORVET membrane tethering complex genetic 1 1 1 Synthetic Growth Defect
DOA4 YDR069C Ubiquitin hydrolase genetic 1 1 1 Synthetic Growth Defect
UFO1 YML088W F-box receptor protein genetic 1 1 1 Synthetic Growth Defect
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
GAS3 YMR215W Putative 1,3-beta-glucanosyltransferase genetic 1 1 1 Positive Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Positive Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
GCV3 YAL044C H subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Negative Genetic
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 1 1 1 Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Negative Genetic
VPS45 YGL095C Protein of the Sec1p/Munc-18 family genetic 1 1 1 Negative Genetic
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis genetic 1 1 1 Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Negative Genetic
MRPL38 YKL170W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 1 1 1 Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Negative Genetic
IRC15 YPL017C Microtubule associated protein genetic 1 1 1 Negative Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 1 1 1 Synthetic Rescue
MUB1 YMR100W MYND domain-containing protein genetic 1 1 1 Synthetic Rescue
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Phenotypic Suppression
RTT106 YNL206C Histone chaperone genetic 1 1 1 Dosage Lethality
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
YLR287C YLR287C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YRA2 YKL214C Member of the REF (RNA and export factor binding proteins) family genetic 1 1 1 Negative Genetic
RNH201 YNL072W Ribonuclease H2 catalytic subunit genetic 1 1 1 Negative Genetic
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes genetic 1 1 1 Negative Genetic
GAL2 YLR081W Galactose permease genetic 1 1 1 Negative Genetic
PGM2 YMR105C Phosphoglucomutase genetic 1 1 1 Negative Genetic
YCR090C YCR090C Putative protein of unknown function genetic 1 1 1 Negative Genetic
FYV4 YHR059W Protein of unknown function genetic 1 1 1 Negative Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 1 1 1 Negative Genetic
MIR1 YJR077C Mitochondrial phosphate carrier genetic 1 1 1 Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
FTR1 YER145C High affinity iron permease genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
PYC2 YBR218C Pyruvate carboxylase isoform genetic 1 1 1 Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
SDD4 YPR022C Putative transcription factor, as suggested by computational analysis genetic 1 1 1 Negative Genetic
FUB1 YCR076C Proteasome-binding protein genetic 1 1 1 Negative Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
FET3 YMR058W Ferro-O2-oxidoreductase genetic 1 1 1 Negative Genetic
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Negative Genetic
DAL3 YIR032C Ureidoglycolate lyase genetic 1 1 1 Negative Genetic
GAL1 YBR020W Galactokinase genetic 1 1 1 Negative Genetic
UBX5 YDR330W UBX domain-containing protein that interacts with Cdc48p genetic 1 1 1 Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Negative Genetic
PFF1 YBR074W Multi-spanning vacuolar membrane protease genetic 1 1 1 Negative Genetic
GRX7 YBR014C Cis-golgi localized monothiol glutaredoxin genetic 1 1 1 Negative Genetic
YIL054W YIL054W Protein of unknown function genetic 1 1 1 Negative Genetic
YBR013C YBR013C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
MCH5 YOR306C Plasma membrane riboflavin transporter genetic 1 1 1 Negative Genetic
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein genetic 1 1 1 Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
KEL2 YGR238C Protein that negatively regulates mitotic exit genetic 1 1 1 Negative Genetic
UBC13 YDR092W E2 ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
SOK1 YDR006C Protein of unknown function genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
GAL10 YBR019C UDP-glucose-4-epimerase genetic 1 1 1 Negative Genetic
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
MET17 YLR303W O-acetyl homoserine-O-acetyl serine sulfhydrylase genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
YBR016W YBR016W Tail-anchored plasma membrane protein with a conserved CYSTM module genetic 1 1 1 Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
TAL1 YLR354C Transaldolase, enzyme in the non-oxidative pentose phosphate pathway genetic 1 1 1 Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
UGA2 YBR006W Succinate semialdehyde dehydrogenase genetic 1 1 1 Negative Genetic
POA1 YBR022W Phosphatase that is highly specific for ADP-ribose 1''-phosphate genetic 1 1 1 Negative Genetic
CST9 YLR394W SUMO E3 ligase genetic 1 1 1 Negative Genetic
YLR297W YLR297W Protein of unknown function genetic 1 1 1 Negative Genetic
SCO2 YBR024W Protein anchored to mitochondrial inner membrane genetic 1 1 1 Negative Genetic
IRC3 YDR332W Double-stranded DNA-dependent helicase of the DExH/D-box family genetic 1 1 1 Negative Genetic
YGR127W YGR127W Putative protein of unknown function genetic 1 1 1 Negative Genetic
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
RAD10 YML095C Single-stranded DNA endonuclease (with Rad1p) genetic 1 1 1 Negative Genetic
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 1 1 1 Negative Genetic
YNL134C YNL134C NADH-dependent aldehyde reductase genetic 1 1 1 Negative Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Negative Genetic
YDR541C YDR541C Aldehyde reductase genetic 1 1 1 Negative Genetic
RGI2 YIL057C Protein of unknown function genetic 1 1 1 Negative Genetic
EDS1 YBR033W Putative zinc cluster protein, predicted to be a transcription factor genetic 1 1 1 Negative Genetic
MET12 YPL023C Protein with MTHFR activity in vitro genetic 1 1 1 Negative Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Negative Genetic
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions genetic 1 1 1 Negative Genetic
RNY1 YPL123C Vacuolar RNase of the T(2) family genetic 1 1 1 Negative Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
SUR7 YML052W Plasma membrane protein, component of eisosomes genetic 1 1 1 Negative Genetic
YOR062C YOR062C Protein of unknown function genetic 1 1 1 Negative Genetic
PEX13 YLR191W Peroxisomal importomer complex component genetic 1 1 1 Negative Genetic
YLL053C YLL053C Putative protein genetic 1 1 1 Negative Genetic
YGL036W YGL036W Putative protein of unknown function genetic 1 1 1 Negative Genetic
DUF1 YOL087C Ubiquitin-binding protein of unknown function genetic 1 1 1 Negative Genetic
EMA19 YLR050C Integral ER membrane protein involved in protein sorting genetic 1 1 1 Negative Genetic
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling genetic 1 1 1 Negative Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Negative Genetic
RPL35B YDL136W Ribosomal 60S subunit protein L35B genetic 1 1 1 Negative Genetic
GDH1 YOR375C NADP(+)-dependent glutamate dehydrogenase genetic 1 1 1 Negative Genetic
FMP45 YDL222C Integral membrane protein localized to mitochondria genetic 1 1 1 Negative Genetic
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 1 1 1 Negative Genetic
RPL4A YBR031W Ribosomal 60S subunit protein L4A genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
MRS2 YOR334W Mitochondrial inner membrane Mg(2+) channel genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Negative Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
EMC10 YDR056C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Negative Genetic
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B genetic 1 1 1 Negative Genetic
SDH2 YLL041C Iron-sulfur protein subunit of succinate dehydrogenase genetic 1 1 1 Negative Genetic
DET1 YDR051C Acid phosphatase genetic 1 1 1 Negative Genetic
VIK1 YPL253C Protein that forms a kinesin-14 heterodimeric motor with Kar3p genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
IRC23 YOR044W Protein of unknown function involved in multidrug resistance genetic 1 1 1 Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Negative Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
SIP1 YDR422C One of three alternate beta-subunits of the Snf1p kinase complex genetic 1 1 1 Negative Genetic
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein genetic 1 1 1 Negative Genetic
SUL2 YLR092W High affinity sulfate permease genetic 1 1 1 Negative Genetic
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
RMD5 YDR255C Component of GID Complex that confers ubiquitin ligase (U3) activity genetic 1 1 1 Negative Genetic
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Negative Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Negative Genetic
DUG2 YBR281C Component of glutamine amidotransferase (GATase II) genetic 1 1 1 Negative Genetic
NTH2 YBR001C Putative neutral trehalase, required for thermotolerance genetic 1 1 1 Negative Genetic
SPO11 YHL022C Meiosis-specific protein required for meiotic recombination genetic 1 1 1 Negative Genetic
RPL16A YIL133C Ribosomal 60S subunit protein L16A genetic 1 1 1 Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
SUL1 YBR294W High affinity sulfate permease of the SulP anion transporter family genetic 1 1 1 Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Negative Genetic
PEX10 YDR265W Peroxisomal membrane E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
RKM3 YBR030W Ribosomal lysine methyltransferase genetic 1 1 1 Negative Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
HEH2 YDR458C Inner nuclear membrane (INM) protein genetic 1 1 1 Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
NQM1 YGR043C Transaldolase of unknown function genetic 1 1 1 Negative Genetic
YJR120W YJR120W Protein of unknown function genetic 1 1 1 Negative Genetic
YNL092W YNL092W S-adenosylmethionine-dependent protein methyltransferase genetic 1 1 1 Negative Genetic
RCF2 YNR018W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
MLO127 YJR039W Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
MBP1 YDL056W Transcription factor genetic 1 1 1 Negative Genetic
YJR079W YJR079W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
HPF1 YOL155C Haze-protective mannoprotein genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
FDC1 YDR539W Ferulic acid decarboxylase genetic 1 1 1 Negative Genetic
DIP5 YPL265W Dicarboxylic amino acid permease genetic 1 1 1 Negative Genetic
YMR196W YMR196W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YHM2 YMR241W Citrate and oxoglutarate carrier protein genetic 1 1 1 Negative Genetic
HOS1 YPR068C Class I histone deacetylase (HDAC) family member genetic 1 1 1 Negative Genetic
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Negative Genetic
NUR1 YDL089W Protein involved in regulation of mitotic exit genetic 1 1 1 Negative Genetic
YGL176C YGL176C Putative protein of unknown function genetic 1 1 1 Negative Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Negative Genetic
YHR022C YHR022C Putative protein of unknown function genetic 1 1 1 Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 1 1 1 Negative Genetic
YFL012W YFL012W Putative protein of unknown function genetic 1 1 1 Negative Genetic
STB3 YDR169C Ribosomal RNA processing element (RRPE)-binding protein genetic 1 1 1 Negative Genetic
ECM30 YLR436C Protein of unknown function genetic 1 1 1 Negative Genetic
YOR338W YOR338W Putative protein of unknown function genetic 1 1 1 Negative Genetic
MSC6 YOR354C Multicopy suppressor of HER2 involved in mitochondrial translation genetic 1 1 1 Negative Genetic
PRR2 YDL214C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SSA3 YBL075C ATPase involved in protein folding and the response to stress genetic 1 1 1 Negative Genetic
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Negative Genetic
GID8 YMR135C Subunit of GID Complex, binds strongly to central component Vid30p genetic 1 1 1 Negative Genetic
UGA4 YDL210W GABA (gamma-aminobutyrate) permease genetic 1 1 1 Negative Genetic
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase genetic 1 1 1 Negative Genetic
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
PMT5 YDL093W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p genetic 1 1 1 Negative Genetic
TPO2 YGR138C Polyamine transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
SLK19 YOR195W Kinetochore-associated protein genetic 1 1 1 Negative Genetic
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 1 1 1 Negative Genetic
MDE1 YJR024C 5'-methylthioribulose-1-phosphate dehydratase genetic 1 1 1 Negative Genetic
RPL38 YLR325C Ribosomal 60S subunit protein L38 genetic 1 1 1 Negative Genetic
EFM6 YNL024C Putative S-adenosylmethionine-dependent lysine methyltransferase genetic 1 1 1 Negative Genetic
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Negative Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Negative Genetic
ZRC1 YMR243C Vacuolar membrane zinc transporter genetic 1 1 1 Negative Genetic
YKE4 YIL023C Zinc transporter genetic 1 1 1 Negative Genetic
DOG1 YHR044C 2-deoxyglucose-6-phosphate phosphatase genetic 1 1 1 Negative Genetic
DCR2 YLR361C Protein phosphatase genetic 1 1 1 Negative Genetic
SWC7 YLR385C Protein of unknown function genetic 1 1 1 Negative Genetic
FLO8 YER109C Transcription factor genetic 1 1 1 Negative Genetic
HOP1 YIL072W Meiosis-specific protein required for chromosome synapsis genetic 1 1 1 Negative Genetic
GRX1 YCL035C Glutathione-dependent disulfide oxidoreductase genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Negative Genetic
YOL153C YOL153C Blocked reading frame, contains two in-frame stops in translation genetic 1 1 1 Negative Genetic
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Negative Genetic
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex genetic 1 1 1 Negative Genetic
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 1 1 1 Negative Genetic
PAI3 YMR174C Cytoplasmic proteinase A (Pep4p) inhibitor genetic 1 1 1 Negative Genetic
RSN1 YMR266W Membrane protein of unknown function genetic 1 1 1 Negative Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Negative Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Negative Genetic
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation genetic 1 1 1 Negative Genetic
YJL027C YJL027C Putative protein of unknown function genetic 1 1 1 Negative Genetic
GRH1 YDR517W Acetylated cis-Golgi protein, homolog of human GRASP65 genetic 1 1 1 Negative Genetic
NMA1 YLR328W Nicotinic acid mononucleotide adenylyltransferase genetic 1 1 1 Negative Genetic
CST26 YBR042C Acyltransferase genetic 1 1 1 Positive Genetic
PMS1 YNL082W ATP-binding protein required for mismatch repair genetic 1 1 1 Positive Genetic
PEA2 YER149C Coiled-coil 12S polarisome subunit genetic 1 1 1 Positive Genetic
GDS1 YOR355W Protein involved in histone H4 acetylation at ribosomal protein genes genetic 1 1 1 Positive Genetic
GUD1 YDL238C Guanine deaminase genetic 1 1 1 Positive Genetic
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Positive Genetic
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 1 1 1 Positive Genetic
MSC7 YHR039C Protein of unknown function genetic 1 1 1 Positive Genetic
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering genetic 1 1 1 Positive Genetic
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex genetic 1 1 1 Positive Genetic
YML119W YML119W Putative protein of unknown function genetic 1 1 1 Positive Genetic
MAL33 YBR297W MAL-activator protein genetic 1 1 1 Positive Genetic
SMN1 YHR202W Putative AMP hydrolase genetic 1 1 1 Positive Genetic
ICS2 YBR157C Protein of unknown function genetic 1 1 1 Positive Genetic
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Positive Genetic
LSB6 YJL100W Type II phosphatidylinositol 4-kinase genetic 1 1 1 Positive Genetic
NRK1 YNL129W Nicotinamide riboside kinase genetic 1 1 1 Positive Genetic
YOL075C YOL075C Putative ABC transporter genetic 1 1 1 Positive Genetic
UIP3 YAR027W Putative integral membrane protein of unknown function genetic 1 1 1 Positive Genetic
DDC1 YPL194W DNA damage checkpoint protein genetic 1 1 1 Positive Genetic
SMP1 YBR182C MADS-box transcription factor involved in osmotic stress response genetic 1 1 1 Positive Genetic
DXO1 YDR370C Cytoplasmic 5' exoribonuclease genetic 1 1 1 Positive Genetic
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway genetic 1 1 1 Positive Genetic
FBP1 YLR377C Fructose-1,6-bisphosphatase genetic 1 1 1 Positive Genetic
DLD2 YDL178W D-2-hydroxyglutarate dehydrogenase, and minor D-lactate dehydrogenase genetic 1 1 1 Positive Genetic
OXP1 YKL215C 5-oxoprolinase genetic 1 1 1 Positive Genetic
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome genetic 1 1 1 Positive Genetic
YCR007C YCR007C Putative integral membrane protein genetic 1 1 1 Positive Genetic
HLR1 YDR528W Protein involved in regulation of cell wall composition and integrity genetic 1 1 1 Positive Genetic
MTO1 YGL236C Mitochondrial protein genetic 1 1 1 Positive Genetic
RSM25 YIL093C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
PBP2 YBR233W RNA binding protein genetic 1 1 1 Positive Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Positive Genetic
MCH4 YOL119C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Positive Genetic
YSC83 YHR017W Non-essential mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
FUN14 YAL008W Integral mitochondrial outer membrane (MOM) protein genetic 1 1 1 Positive Genetic
YPS5 YGL259W Protein with similarity to GPI-anchored aspartic proteases genetic 1 1 1 Positive Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Positive Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Positive Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Positive Genetic
YOR289W YOR289W Putative protein of unknown function genetic 1 1 1 Positive Genetic
MOH1 YBL049W Protein of unknown function, essential for stationary phase survival genetic 1 1 1 Positive Genetic
PHO92 YDR374C Posttranscriptional regulator of phosphate and glucose metabolism genetic 1 1 1 Positive Genetic
YDR514C YDR514C Protein of unknown function that localizes to mitochondria genetic 1 1 1 Positive Genetic
UPS2 YLR168C Mitochondrial intermembrane space protein genetic 1 1 1 Positive Genetic
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
MDM30 YLR368W F-box component of an SCF ubiquitin protein ligase complex genetic 1 1 1 Positive Genetic
YAR1 YPL239W Nucleocytoplasmic shuttling assembly chaperone genetic 1 1 1 Positive Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Positive Genetic
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme genetic 1 1 1 Positive Genetic
TPO1 YLL028W Polyamine transporter of the major facilitator superfamily genetic 1 1 1 Positive Genetic
RPS1A YLR441C Ribosomal protein of the small (40S) subunit genetic 1 1 1 Positive Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Positive Genetic
TAX4 YJL083W EH domain-containing protein genetic 1 1 1 Positive Genetic
YLL054C YLL054C Putative protein of unknown function with similarity to Pip2p genetic 1 1 1 Positive Genetic
YPR084W YPR084W Putative protein of unknown function genetic 1 1 1 Positive Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Positive Genetic
INP2 YMR163C Peroxisome-specific receptor important for peroxisome inheritance genetic 1 1 1 Positive Genetic
TIF2 YJL138C Translation initiation factor eIF4A genetic 1 1 1 Positive Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Positive Genetic
OCA2 YNL056W Protein of unknown function genetic 1 1 1 Positive Genetic
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex genetic 1 1 1 Positive Genetic
DIE2 YGR227W Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase genetic 1 1 1 Positive Genetic
MTC6 YHR151C Protein of unknown function genetic 1 1 1 Positive Genetic
YOR296W YOR296W Putative protein of unknown function genetic 1 1 1 Positive Genetic
NTG1 YAL015C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Positive Genetic
URA4 YLR420W Dihydroorotase genetic 1 1 1 Positive Genetic
KTR4 YBR199W Glycosyltransferase involved in protein glycosylation genetic 1 1 1 Positive Genetic
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor genetic 1 1 1 Positive Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
MDM36 YPR083W Mitochondrial protein genetic 1 1 1 Positive Genetic
MVB12 YGR206W ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers genetic 1 1 1 Positive Genetic
YCF1 YDR135C Vacuolar glutathione S-conjugate transporter genetic 1 1 1 Positive Genetic
FRE7 YOL152W Putative ferric reductase with similarity to Fre2p genetic 1 1 1 Positive Genetic
YJL132W YJL132W Putative protein of unknown function genetic 1 1 1 Positive Genetic
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function genetic 1 1 1 Positive Genetic
TDP1 YBR223C Tyrosyl-DNA phosphodiesterase I genetic 1 1 1 Positive Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Positive Genetic
GAT3 YLR013W Protein containing GATA family zinc finger motifs genetic 1 1 1 Positive Genetic
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Positive Genetic
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Positive Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
MKK2 YPL140C MAPKK involved in the protein kinase C signaling pathway genetic 1 1 1 Positive Genetic
NCW2 YLR194C GPI-anchored protein involved in cell wall remodeling genetic 1 1 1 Positive Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Positive Genetic
MRX8 YDR336W Protein that associates with mitochondrial ribosome genetic 1 1 1 Positive Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Positive Genetic
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 genetic 1 1 1 Positive Genetic
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Positive Genetic
MME1 YMR166C Transporter of the mitochondrial inner membrane that exports magnesium genetic 1 1 1 Positive Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 1 1 1 Positive Genetic
HPM1 YIL110W AdoMet-dependent methyltransferase genetic 1 1 1 Positive Genetic
MIL1 YFL034W Predicted lipase genetic 1 1 1 Positive Genetic
YDR476C YDR476C Putative protein of unknown function genetic 1 1 1 Positive Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Positive Genetic
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Positive Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Positive Genetic
RPL36A YMR194W Ribosomal 60S subunit protein L36A genetic 1 1 1 Positive Genetic
FAR7 YFR008W Protein involved in recovery from pheromone-induced cell cycle arrest genetic 1 1 1 Positive Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Positive Genetic
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Positive Genetic
SDS23 YGL056C Protein involved in cell separation during budding genetic 1 1 1 Positive Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Positive Genetic
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Positive Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Positive Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Positive Genetic
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 1 1 1 Positive Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Positive Genetic
OPY1 YBR129C Protein of unknown function genetic 1 1 1 Positive Genetic
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Positive Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 1 1 1 Positive Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 1 1 1 Positive Genetic
SCS22 YBL091C-A Protein involved in regulation of phospholipid metabolism genetic 1 1 1 Positive Genetic
THI20 YOL055C Trifunctional enzyme of thiamine biosynthesis, degradation and salvage genetic 1 1 1 Positive Genetic
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Positive Genetic
SPS4 YOR313C Protein whose expression is induced during sporulation genetic 1 1 1 Positive Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Positive Genetic
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
SYN8 YAL014C Endosomal SNARE related to mammalian syntaxin 8 genetic 1 1 1 Positive Genetic
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
RAD59 YDL059C Protein involved DNA double-strand break repair genetic 1 1 1 Positive Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Positive Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Positive Genetic
OPI10 YOL032W Protein with a possible role in phospholipid biosynthesis genetic 1 1 1 Positive Genetic
MSH4 YFL003C Protein involved in meiotic recombination genetic 1 1 1 Positive Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
YBP1 YBR216C Protein involved in cellular response to oxidative stress genetic 1 1 1 Positive Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Positive Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Positive Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Positive Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Positive Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Synthetic Growth Defect
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 1 1 1 Synthetic Growth Defect
HRP1 YOL123W Subunit of cleavage factor I genetic 1 1 1 Synthetic Growth Defect
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Synthetic Growth Defect
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Synthetic Growth Defect
UBI4 YLL039C Ubiquitin genetic 1 1 1 Dosage Rescue
BRN1 YBL097W Subunit of the condensin complex physical 1 1 1 Affinity Capture-MS
BIK1 YCL029C Microtubule-associated protein genetic 1 1 1 Negative Genetic
CBF2 YGR140W Essential kinetochore protein physical 1 1 1 Co-localization
BUD8 YLR353W Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
CHS3 YBR023C Chitin synthase III genetic 1 1 1 Negative Genetic
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
CHS5 YLR330W Component of the exomer complex physical 1 1 1 Affinity Capture-MS
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Positive Genetic
APN2 YBL019W Class II abasic (AP) endonuclease involved in repair of DNA damage genetic 1 1 1 Negative Genetic
ARO80 YDR421W Zinc finger transcriptional activator of the Zn2Cys6 family genetic 1 1 1 Positive Genetic
CNN1 YFR046C Kinetochore protein genetic 1 1 1 Synthetic Growth Defect
CIT1 YNR001C Mitochondrial citrate synthase genetic 1 1 1 Positive Genetic
ATF1 YOR377W Alcohol acetyltransferase genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
BNS1 YGR230W Protein of unknown function genetic 1 1 1 Positive Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 1 1 1 Negative Genetic
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase genetic 1 1 1 Positive Genetic
COQ10 YOL008W Coenzyme Q (ubiquinone) binding protein genetic 1 1 1 Positive Genetic
COQ11 YLR290C Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes genetic 1 1 1 Positive Genetic
BIL1 YOR304C-A Protein that binds Bud6p and has a role in actin cable assembly genetic 1 1 1 Positive Genetic
ATG33 YLR356W Mitochondrial mitophagy-specific protein genetic 1 1 1 Negative Genetic
ABZ2 YMR289W Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase) genetic 1 1 1 Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 1 1 1 Positive Genetic
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 PCA
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation genetic 1 1 1 Negative Genetic
AIM11 YER093C-A Protein of unknown function genetic 1 1 1 Negative Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 1 1 1 Positive Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Positive Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Positive Genetic
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 1 1 1 Negative Genetic
ALK1 YGL021W Atypical protein kinase physical 1 1 1 Affinity Capture-MS
BER1 YLR412W Protein involved in microtubule-related processes genetic 1 1 1 Positive Genetic
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease genetic 1 1 1 Negative Genetic
ALG8 YOR067C Glucosyl transferase genetic 1 1 1 Positive Genetic
COA6 YMR244C-A Protein involved in cytochrome c oxidase (Complex IV) assembly genetic 1 1 1 Positive Genetic
BNA4 YBL098W Kynurenine 3-monooxygenase genetic 1 1 1 Positive Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic