Standard name Systematic name Name description Description
TUB4 YLR212C Gamma-tubulin Gamma-tubulin; involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body; protein abundance increases in response to DNA replication stress; null mutation is complemented by human TUBG1
Visualize the interactome of TUB4
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1/S 46

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.969 1.0 0.992

GFP localization & abundance

GFP localization GFP abundance
spindle pole 7200

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TUB4 1 1 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex physical 25 5 16 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, FRET, FRET, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
SPC98 YNL126W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex physical 11 4 8 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western
SPC110 YDR356W Inner plaque spindle pole body (SPB) component physical 11 5 6 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Co-purification, FRET, FRET, Affinity Capture-Western, Reconstituted Complex
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 9 5 5 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Co-localization, Reconstituted Complex, Co-fractionation
SPC98 YNL126W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 8 4 4 Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Phenotypic Suppression, Phenotypic Enhancement
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 6 3 5 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect
BIM1 YER016W Microtubule plus end-tracking protein genetic 4 3 3 Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect
CDC73 YLR418C Component of the Paf1p complex genetic 3 3 3 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 3 3 3 Negative Genetic, Positive Genetic, Synthetic Rescue
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 3 3 3 Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 3 3 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 3 3 2 Synthetic Lethality, Synthetic Rescue, Synthetic Growth Defect
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 3 3 2 Negative Genetic, Synthetic Rescue, Synthetic Growth Defect
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 3 2 2 Synthetic Haploinsufficiency, Synthetic Haploinsufficiency, Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 2 2 2 Dosage Rescue, Synthetic Rescue
LSM1 YJL124C Lsm (Like Sm) protein genetic 2 2 2 Positive Genetic, Synthetic Rescue
DST1 YGL043W General transcription elongation factor TFIIS genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 2 2 2 Dosage Rescue, Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 2 2 2 Positive Genetic, Synthetic Rescue
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
TIF1 YKR059W Translation initiation factor eIF4A genetic 2 2 2 Negative Genetic, Synthetic Rescue
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 2 Synthetic Lethality, Positive Genetic
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor genetic 2 2 2 Dosage Rescue, Synthetic Growth Defect
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
KAR3 YPR141C Minus-end-directed microtubule motor genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RTT109 YLL002W Histone acetyltransferase genetic 2 2 2 Positive Genetic, Synthetic Rescue
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 2 2 2 Negative Genetic, Synthetic Rescue
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 2 2 2 Negative Genetic, Synthetic Rescue
RTC6 YPL183W-A Protein involved in translation genetic 2 2 2 Negative Genetic, Synthetic Rescue
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BUB2 YMR055C Mitotic exit network regulator genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 2 2 1 PCA, Biochemical Activity
AEP2 YMR282C Mitochondrial protein genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SKI3 YPR189W Ski complex component and TPR protein genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
ATG29 YPL166W Autophagy-specific protein genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
HUA2 YOR284W Cytoplasmic protein of unknown function genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
YPL225W YPL225W Protein of unknown function genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
YOR342C YOR342C Protein of unknown function genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
TUM1 YOR251C Rhodanese domain sulfur transferase genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
YPR071W YPR071W Putative membrane protein genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
JNM1 YMR294W Component of the yeast dynactin complex genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family physical 2 2 1 Reconstituted Complex, Co-fractionation
RPL33B YOR234C Ribosomal 60S subunit protein L33B genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
RTT106 YNL206C Histone chaperone genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
FSF1 YOR271C Putative protein genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Synthetic Growth Defect
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Negative Genetic
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Synthetic Rescue
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
NOP16 YER002W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Synthetic Rescue
RPL16A YIL133C Ribosomal 60S subunit protein L16A genetic 1 1 1 Synthetic Rescue
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Synthetic Rescue
HOL1 YNR055C Putative transporter in the major facilitator superfamily genetic 1 1 1 Synthetic Rescue
NUC1 YJL208C Major mitochondrial nuclease genetic 1 1 1 Synthetic Rescue
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Synthetic Growth Defect
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Positive Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes genetic 1 1 1 Positive Genetic
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Synthetic Growth Defect
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases genetic 1 1 1 Synthetic Rescue
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family genetic 1 1 1 Synthetic Rescue
PUS7 YOR243C Pseudouridine synthase genetic 1 1 1 Synthetic Growth Defect
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Synthetic Growth Defect
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
TIF2 YJL138C Translation initiation factor eIF4A genetic 1 1 1 Synthetic Growth Defect
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Synthetic Rescue
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Synthetic Rescue
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Synthetic Rescue
TEX1 YNL253W Protein involved in mRNA export genetic 1 1 1 Synthetic Rescue
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Synthetic Rescue
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Synthetic Rescue
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Synthetic Rescue
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Synthetic Growth Defect
IMD3 YLR432W Inosine monophosphate dehydrogenase genetic 1 1 1 Synthetic Rescue
SSD1 YDR293C Translational repressor genetic 1 1 1 Synthetic Growth Defect
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Synthetic Growth Defect
PUF6 YDR496C Pumilio-homology domain protein genetic 1 1 1 Synthetic Growth Defect
TSR2 YLR435W Protein with a potential role in pre-rRNA processing genetic 1 1 1 Synthetic Rescue
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) genetic 1 1 1 Synthetic Growth Defect
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Synthetic Growth Defect
CAF40 YNL288W Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Rescue
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
ATP11 YNL315C Molecular chaperone genetic 1 1 1 Synthetic Rescue
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Synthetic Growth Defect
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Synthetic Rescue
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Synthetic Rescue
FRS1 YLR060W Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase genetic 1 1 1 Positive Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Synthetic Growth Defect
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B genetic 1 1 1 Synthetic Growth Defect
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking genetic 1 1 1 Synthetic Rescue
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Synthetic Growth Defect
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HIS4 YCL030C Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase genetic 1 1 1 Synthetic Growth Defect
HST1 YOL068C NAD(+)-dependent histone deacetylase genetic 1 1 1 Synthetic Rescue
IOC3 YFR013W Subunit of the Isw1a complex genetic 1 1 1 Synthetic Rescue
KGD1 YIL125W Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex genetic 1 1 1 Synthetic Growth Defect
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
MAL12 YGR292W Maltase (alpha-D-glucosidase) genetic 1 1 1 Negative Genetic
MBP1 YDL056W Transcription factor genetic 1 1 1 Synthetic Rescue
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Negative Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Synthetic Growth Defect
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
EHD3 YDR036C 3-hydroxyisobutyryl-CoA hydrolase genetic 1 1 1 Synthetic Growth Defect
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 1 1 1 Affinity Capture-MS
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Synthetic Rescue
MLC2 YPR188C Regulatory light chain for the type II myosin Myo1p genetic 1 1 1 Synthetic Growth Defect
CMD1 YBR109C Calmodulin physical 1 1 1 Affinity Capture-Western
CMD1 YBR109C Calmodulin genetic 1 1 1 Dosage Rescue
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Synthetic Growth Defect
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Synthetic Rescue
HER1 YOR227W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Synthetic Rescue
NPL4 YBR170C Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase genetic 1 1 1 Synthetic Growth Defect
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex physical 1 1 1 Affinity Capture-Western
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex physical 1 1 1 Affinity Capture-Western
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Synthetic Lethality
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex physical 1 1 1 Affinity Capture-Western
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Synthetic Lethality
PCF11 YDR228C mRNA 3' end processing factor genetic 1 1 1 Negative Genetic
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex genetic 1 1 1 Synthetic Rescue
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Synthetic Growth Defect
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Synthetic Growth Defect
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Synthetic Growth Defect
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Synthetic Growth Defect
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome genetic 1 1 1 Synthetic Rescue
MIR1 YJR077C Mitochondrial phosphate carrier genetic 1 1 1 Synthetic Rescue
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Synthetic Rescue
ADE57 YGL234W Bifunctional enzyme of 'de novo' purine nucleotide pathway genetic 1 1 1 Synthetic Growth Defect
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Rescue
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Rescue
RKM1 YPL208W SET-domain lysine-N-methyltransferase genetic 1 1 1 Synthetic Growth Defect
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Synthetic Rescue
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Synthetic Rescue
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Synthetic Growth Defect
SGN1 YIR001C Cytoplasmic RNA-binding protein genetic 1 1 1 Synthetic Rescue
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Synthetic Rescue
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Synthetic Rescue
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
AVT4 YNL101W Vacuolar transporter genetic 1 1 1 Synthetic Rescue
HRK1 YOR267C Protein kinase genetic 1 1 1 Synthetic Growth Defect
BSP1 YPR171W Adapter that links synaptojanins to the cortical actin cytoskeleton genetic 1 1 1 Synthetic Growth Defect
SLC1 YDL052C 1-acyl-sn-glycerol-3-phosphate acyltransferase genetic 1 1 1 Synthetic Growth Defect
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
SEC17 YBL050W Alpha-SNAP cochaperone genetic 1 1 1 Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Synthetic Growth Defect
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Synthetic Growth Defect
SPE3 YPR069C Spermidine synthase genetic 1 1 1 Synthetic Growth Defect
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Synthetic Rescue
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 1 1 1 Synthetic Growth Defect
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Synthetic Growth Defect
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Synthetic Growth Defect
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Positive Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Positive Genetic
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering genetic 1 1 1 Synthetic Growth Defect
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Synthetic Growth Defect
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Synthetic Growth Defect
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
CAM1 YPL048W One of two isoforms of the gamma subunit of eEF1B genetic 1 1 1 Synthetic Rescue
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Synthetic Rescue
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
TKL1 YPR074C Transketolase genetic 1 1 1 Synthetic Growth Defect
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Synthetic Growth Defect
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Synthetic Growth Defect
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Synthetic Growth Defect
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Synthetic Growth Defect
TRP2 YER090W Anthranilate synthase genetic 1 1 1 Synthetic Growth Defect
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 1 1 1 Dosage Rescue
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Synthetic Growth Defect
ECM30 YLR436C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ALT2 YDR111C Catalytically inactive alanine transaminase genetic 1 1 1 Synthetic Growth Defect
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Synthetic Growth Defect
SAW1 YAL027W 5'- and 3'-flap DNA binding protein genetic 1 1 1 Synthetic Growth Defect
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
SPP1 YPL138C Subunit of COMPASS (Set1C) genetic 1 1 1 Synthetic Growth Defect
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Synthetic Growth Defect
SLX9 YGR081C Protein required for pre-rRNA processing genetic 1 1 1 Synthetic Rescue
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 1 1 1 Synthetic Growth Defect
FAR11 YNL127W Protein involved in recovery from cell cycle arrest genetic 1 1 1 Synthetic Rescue
LYS9 YNR050C Saccharopine dehydrogenase (NADP+, L-glutamate-forming) genetic 1 1 1 Synthetic Rescue
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Synthetic Rescue
CIR2 YOR356W Putative ortholog of human ETF-dH genetic 1 1 1 Synthetic Growth Defect
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Negative Genetic
AIM41 YOR215C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Synthetic Rescue
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Synthetic Growth Defect
LSP1 YPL004C Eisosome core component genetic 1 1 1 Synthetic Growth Defect
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane genetic 1 1 1 Synthetic Rescue
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Synthetic Growth Defect
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex genetic 1 1 1 Synthetic Growth Defect
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Synthetic Growth Defect
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Synthetic Rescue
ATG31 YDR022C Autophagy-specific protein required for autophagosome formation genetic 1 1 1 Synthetic Rescue
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator genetic 1 1 1 Synthetic Growth Defect
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase genetic 1 1 1 Synthetic Rescue
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity genetic 1 1 1 Synthetic Growth Defect
SER1 YOR184W 3-phosphoserine aminotransferase genetic 1 1 1 Synthetic Growth Defect
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Synthetic Rescue
CNA1 YLR433C Calcineurin A genetic 1 1 1 Synthetic Rescue
CNB1 YKL190W Calcineurin B genetic 1 1 1 Synthetic Rescue
GDE1 YPL110C Glycerophosphocholine (GroPCho) phosphodiesterase genetic 1 1 1 Synthetic Growth Defect
FKH1 YIL131C Forkhead family transcription factor genetic 1 1 1 Synthetic Growth Defect
FDO1 YMR144W Protein involved in directionality of mating type switching genetic 1 1 1 Synthetic Rescue
BUD13 YGL174W Subunit of the RES complex genetic 1 1 1 Synthetic Growth Defect
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Synthetic Growth Defect
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Synthetic Rescue
AMF1 YOR378W Low affinity NH4+ transporter genetic 1 1 1 Synthetic Growth Defect
ENV7 YPL236C Vacuolar membrane protein kinase genetic 1 1 1 Synthetic Growth Defect
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Synthetic Growth Defect
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation genetic 1 1 1 Synthetic Rescue
DDC1 YPL194W DNA damage checkpoint protein genetic 1 1 1 Synthetic Growth Defect
ARG4 YHR018C Argininosuccinate lyase genetic 1 1 1 Synthetic Growth Defect
OM45 YIL136W Mitochondrial outer membrane protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SOD2 YHR008C Mitochondrial manganese superoxide dismutase genetic 1 1 1 Synthetic Growth Defect
APT1 YML022W Adenine phosphoribosyltransferase genetic 1 1 1 Synthetic Rescue
AIP1 YMR092C Actin cortical patch component genetic 1 1 1 Synthetic Rescue
DAS1 YJL149W Putative SCF ubiquitin ligase F-box protein genetic 1 1 1 Synthetic Rescue
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Synthetic Growth Defect
GID8 YMR135C Subunit of GID Complex, binds strongly to central component Vid30p genetic 1 1 1 Synthetic Rescue
PSK2 YOL045W PAS-domain containing serine/threonine protein kinase genetic 1 1 1 Synthetic Rescue
ARE2 YNR019W Acyl-CoA:sterol acyltransferase genetic 1 1 1 Synthetic Rescue
ATG7 YHR171W Autophagy-related protein and dual specificity member of the E1 family genetic 1 1 1 Synthetic Rescue
ETP1 YHL010C Protein of unknown function required for growth on ethanol physical 1 1 1 Two-hybrid
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone genetic 1 1 1 Synthetic Growth Defect
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
LTP1 YPR073C Protein phosphotyrosine phosphatase of unknown cellular role genetic 1 1 1 Synthetic Growth Defect
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Synthetic Growth Defect
LRO1 YNR008W Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) genetic 1 1 1 Synthetic Rescue
PEX6 YNL329C AAA-peroxin genetic 1 1 1 Synthetic Growth Defect
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Synthetic Rescue
PBA1 YLR199C Protein involved in 20S proteasome assembly genetic 1 1 1 Synthetic Growth Defect
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Synthetic Rescue
TMA19 YKL056C Protein that associates with ribosomes genetic 1 1 1 Synthetic Rescue
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Synthetic Growth Defect
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) genetic 1 1 1 Synthetic Rescue
AIM46 YHR199C Protein of unknown function genetic 1 1 1 Synthetic Rescue
PDX1 YGR193C E3-binding protein of the mitochondrial pyruvate dehydrogenase complex genetic 1 1 1 Synthetic Rescue
ARE1 YCR048W Acyl-CoA:sterol acyltransferase physical 1 1 1 Two-hybrid
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Synthetic Rescue
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Synthetic Rescue
FAA1 YOR317W Long chain fatty acyl-CoA synthetase genetic 1 1 1 Synthetic Growth Defect
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 1 1 1 Synthetic Growth Defect
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Synthetic Growth Defect
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Negative Genetic
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Synthetic Rescue
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
BUD7 YOR299W Member of the ChAPs family (Chs5p-Arf1p-binding proteins) genetic 1 1 1 Synthetic Growth Defect
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Synthetic Growth Defect
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) genetic 1 1 1 Synthetic Growth Defect
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Synthetic Rescue
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) genetic 1 1 1 Synthetic Rescue
LSC1 YOR142W Alpha subunit of succinyl-CoA ligase genetic 1 1 1 Synthetic Rescue
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase genetic 1 1 1 Synthetic Rescue
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Synthetic Growth Defect
MIH1 YMR036C Protein tyrosine phosphatase genetic 1 1 1 Synthetic Rescue
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 1 1 1 Synthetic Growth Defect
PTP2 YOR208W Phosphotyrosine-specific phosphatase genetic 1 1 1 Synthetic Growth Defect
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Rescue
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Synthetic Rescue
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Synthetic Growth Defect
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Synthetic Growth Defect
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases genetic 1 1 1 Synthetic Rescue
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Synthetic Rescue
SNO2 YNL334C Protein of unknown function genetic 1 1 1 Synthetic Rescue
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Synthetic Growth Defect
NDE1 YMR145C Mitochondrial external NADH dehydrogenase genetic 1 1 1 Synthetic Rescue
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Synthetic Rescue
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Synthetic Growth Defect
LOS1 YKL205W Nuclear pore protein genetic 1 1 1 Synthetic Rescue
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 1 1 1 Synthetic Growth Defect
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
AVT2 YEL064C Putative transporter genetic 1 1 1 Synthetic Growth Defect
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Synthetic Rescue
MSG5 YNL053W Dual-specificity protein phosphatase genetic 1 1 1 Synthetic Growth Defect
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Negative Genetic
DUF1 YOL087C Ubiquitin-binding protein of unknown function genetic 1 1 1 Synthetic Growth Defect
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Synthetic Growth Defect
CBR1 YIL043C Cytochrome b reductase and NADH-dependent reductase for Dph3p genetic 1 1 1 Synthetic Rescue
ADH6 YMR318C NADPH-dependent medium chain alcohol dehydrogenase genetic 1 1 1 Synthetic Rescue
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase genetic 1 1 1 Synthetic Rescue
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Synthetic Rescue
RIM11 YMR139W Protein kinase genetic 1 1 1 Synthetic Rescue
DAP1 YPL170W Heme-binding protein genetic 1 1 1 Synthetic Growth Defect
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Synthetic Growth Defect
GCY1 YOR120W Glycerol dehydrogenase genetic 1 1 1 Synthetic Rescue
MET16 YPR167C 3'-phosphoadenylsulfate reductase genetic 1 1 1 Synthetic Growth Defect
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis genetic 1 1 1 Synthetic Rescue
RAD28 YDR030C Protein involved in DNA repair genetic 1 1 1 Synthetic Growth Defect
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 1 1 1 Synthetic Rescue
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
RED1 YLR263W Protein component of the synaptonemal complex axial elements genetic 1 1 1 Synthetic Growth Defect
PSO2 YMR137C Nuclease required for DNA single- and double-strand break repair genetic 1 1 1 Synthetic Rescue
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
CRC1 YOR100C Mitochondrial inner membrane carnitine transporter genetic 1 1 1 Synthetic Rescue
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
CUE5 YOR042W Ubiquitin-binding protein genetic 1 1 1 Synthetic Rescue
SNZ2 YNL333W Protein involved in thiamine and pyridoxine biosynthesis genetic 1 1 1 Synthetic Rescue
PEX29 YDR479C ER-resident protein involved in peroxisomal biogenesis genetic 1 1 1 Synthetic Rescue
ADE8 YDR408C Phosphoribosyl-glycinamide transformylase genetic 1 1 1 Synthetic Growth Defect
CIN4 YMR138W GTP-binding protein involved in beta-tubulin (Tub2p) folding genetic 1 1 1 Synthetic Rescue
ECM31 YBR176W Ketopantoate hydroxymethyltransferase genetic 1 1 1 Synthetic Growth Defect
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 1 1 1 Synthetic Rescue
ARG81 YML099C Zinc finger transcription factor involved in arginine-responsive genes genetic 1 1 1 Synthetic Rescue
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Synthetic Rescue
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Synthetic Rescue
GDS1 YOR355W Protein involved in histone H4 acetylation at ribosomal protein genes genetic 1 1 1 Synthetic Growth Defect
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Synthetic Rescue
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Synthetic Growth Defect
ISU2 YOR226C Mitochondrial protein required for iron-sulfur protein synthesis genetic 1 1 1 Synthetic Growth Defect
MPD2 YOL088C Member of the protein disulfide isomerase (PDI) family genetic 1 1 1 Synthetic Rescue
MSN5 YDR335W Karyopherin genetic 1 1 1 Synthetic Growth Defect
PEX21 YGR239C Peroxin required for peroxisomal matrix protein targeting genetic 1 1 1 Synthetic Growth Defect
CLG1 YGL215W Cyclin-like protein that interacts with Pho85p genetic 1 1 1 Synthetic Growth Defect
PCL8 YPL219W Cyclin genetic 1 1 1 Synthetic Growth Defect
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 1 1 1 Synthetic Rescue
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) genetic 1 1 1 Synthetic Rescue
RRN10 YBL025W Protein involved in promoting high level transcription of rDNA genetic 1 1 1 Synthetic Growth Defect
ATG34 YOL083W Receptor protein involved in selective autophagy during starvation genetic 1 1 1 Synthetic Rescue
GNP1 YDR508C Broad specificity amino acid permease genetic 1 1 1 Synthetic Growth Defect
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Negative Genetic
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Synthetic Growth Defect
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 1 1 1 Synthetic Rescue
PFS1 YHR185C Sporulation protein required for prospore membrane formation genetic 1 1 1 Synthetic Rescue
SSP1 YHR184W Protein involved in the control of meiotic nuclear division genetic 1 1 1 Synthetic Rescue
STD1 YOR047C Protein involved in control of glucose-regulated gene expression genetic 1 1 1 Synthetic Growth Defect
PRM3 YPL192C Protein required for nuclear envelope fusion during karyogamy genetic 1 1 1 Synthetic Growth Defect
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Rescue
DAS2 YDR020C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay genetic 1 1 1 Synthetic Rescue
SNA3 YJL151C Protein involved in efficient MVB sorting of proteins to the vacuole genetic 1 1 1 Synthetic Rescue
PRM9 YAR031W Pheromone-regulated protein genetic 1 1 1 Synthetic Growth Defect
MVP1 YMR004W Protein required for sorting proteins to the vacuole genetic 1 1 1 Synthetic Growth Defect
LAM6 YLR072W Sterol transporter that transfers sterols between membranes genetic 1 1 1 Negative Genetic
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance genetic 1 1 1 Synthetic Rescue
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
ITT1 YML068W Protein that modulates the efficiency of translation termination genetic 1 1 1 Synthetic Rescue
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Synthetic Rescue
SWM2 YNR004W Protein with a role in snRNA and snoRNA cap trimethylation genetic 1 1 1 Synthetic Rescue
FMP40 YPL222W Mitochondrial AMPylator in the pseudokinase selenoprotein-O family genetic 1 1 1 Synthetic Growth Defect
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Synthetic Growth Defect
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Positive Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Synthetic Rescue
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Synthetic Rescue
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p genetic 1 1 1 Synthetic Growth Defect
PEX17 YNL214W Membrane peroxin of the peroxisomal importomer complex genetic 1 1 1 Synthetic Growth Defect
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Synthetic Growth Defect
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family genetic 1 1 1 Synthetic Growth Defect
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 1 1 1 Synthetic Rescue
RPL9B YNL067W Ribosomal 60S subunit protein L9B genetic 1 1 1 Synthetic Rescue
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Synthetic Growth Defect
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Synthetic Rescue
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Synthetic Growth Defect
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Synthetic Growth Defect
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) genetic 1 1 1 Synthetic Growth Defect
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Positive Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Synthetic Growth Defect
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Synthetic Growth Defect
RPS1A YLR441C Ribosomal protein of the small (40S) subunit genetic 1 1 1 Synthetic Rescue
RPL20B YOR312C Ribosomal 60S subunit protein L20B genetic 1 1 1 Synthetic Rescue
RPS1B YML063W Ribosomal protein of the small (40S) subunit genetic 1 1 1 Synthetic Rescue
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ELO3 YLR372W Elongase genetic 1 1 1 Synthetic Rescue
HOS1 YPR068C Class I histone deacetylase (HDAC) family member genetic 1 1 1 Synthetic Growth Defect
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Synthetic Growth Defect
KAR3 YPR141C Minus-end-directed microtubule motor physical 1 1 1 Reconstituted Complex
KAR9 YPL269W Spindle positioning factor genetic 1 1 1 Phenotypic Enhancement
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Synthetic Rescue
PEA2 YER149C Coiled-coil 12S polarisome subunit genetic 1 1 1 Synthetic Growth Defect
PNG1 YPL096W Conserved peptide N-glycanase genetic 1 1 1 Synthetic Growth Defect
PUP1 YOR157C Beta 2 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RFM1 YOR279C Component of the Sum1p-Rfm1p-Hst1p complex genetic 1 1 1 Synthetic Growth Defect
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Synthetic Growth Defect
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Positive Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport genetic 1 1 1 Synthetic Lethality
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 1 1 1 Synthetic Growth Defect
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Synthetic Rescue
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Synthetic Growth Defect
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex physical 1 1 1 Affinity Capture-Western
TUB4 YLR212C Gamma-tubulin physical 1 1 1 Two-hybrid
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 1 1 1 Negative Genetic
YKL075C YKL075C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YLR053C YLR053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein genetic 1 1 1 Synthetic Rescue
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 1 1 1 Synthetic Rescue
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Synthetic Rescue
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 1 1 1 Synthetic Rescue
YMD8 YML038C Putative nucleotide sugar transporter genetic 1 1 1 Synthetic Rescue
VAC14 YLR386W Enzyme regulator genetic 1 1 1 Synthetic Rescue
YTP1 YNL237W Probable type-III integral membrane protein of unknown function genetic 1 1 1 Synthetic Rescue
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Synthetic Rescue
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme genetic 1 1 1 Synthetic Rescue
YNR029C YNR029C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Synthetic Rescue
YIM1 YMR152W Aldehyde reductase genetic 1 1 1 Synthetic Rescue
YML108W YML108W Protein of unknown function genetic 1 1 1 Synthetic Rescue
YNR021W YNR021W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YVC1 YOR087W Vacuolar cation channel genetic 1 1 1 Synthetic Rescue
YJL206C YJL206C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YAP1801 YHR161C Protein of the AP180 family, involved in clathrin cage assembly genetic 1 1 1 Synthetic Rescue
YJL213W YJL213W Protein of unknown function that may interact with ribosomes genetic 1 1 1 Synthetic Rescue
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Synthetic Rescue
YHL008C YHL008C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Synthetic Rescue
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 1 1 1 Synthetic Rescue
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation genetic 1 1 1 Synthetic Rescue
YIL165C YIL165C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
UBC8 YEL012W Ubiquitin-conjugating enzyme that regulates gluconeogenesis genetic 1 1 1 Synthetic Rescue
YSP3 YOR003W Putative precursor of the subtilisin-like protease III genetic 1 1 1 Synthetic Rescue
VID28 YIL017C GID Complex subunit, serves as adaptor for regulatory subunit Vid24p genetic 1 1 1 Synthetic Rescue
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Rescue
YHR022C YHR022C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
URA4 YLR420W Dihydroorotase genetic 1 1 1 Synthetic Rescue
YHL017W YHL017W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YGR111W YGR111W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YHM2 YMR241W Citrate and oxoglutarate carrier protein genetic 1 1 1 Synthetic Rescue
YML053C YML053C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YFL012W YFL012W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YOR111W YOR111W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YIL152W YIL152W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YHR033W YHR033W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YNL134C YNL134C NADH-dependent aldehyde reductase genetic 1 1 1 Synthetic Rescue
YML037C YML037C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
TWF1 YGR080W Twinfilin genetic 1 1 1 Synthetic Rescue
YOR019W YOR019W Protein of unknown function genetic 1 1 1 Synthetic Rescue
YOL057W YOL057W Dipeptidyl-peptidase III genetic 1 1 1 Synthetic Rescue
YNR014W YNR014W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YOR012W YOR012W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
WAR1 YML076C Homodimeric Zn2Cys6 zinc finger transcription factor genetic 1 1 1 Synthetic Rescue
YKE4 YIL023C Zinc transporter genetic 1 1 1 Synthetic Rescue
VID24 YBR105C GID Complex regulatory subunit genetic 1 1 1 Synthetic Rescue
YOL163W YOL163W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YHK8 YHR048W Presumed antiporter of the major facilitator superfamily genetic 1 1 1 Synthetic Rescue
WSC4 YHL028W Endoplasmic reticulum (ER) membrane protein genetic 1 1 1 Synthetic Rescue
YOX1 YML027W Homeobox transcriptional repressor genetic 1 1 1 Synthetic Rescue
YOR062C YOR062C Protein of unknown function genetic 1 1 1 Synthetic Rescue
YNL190W YNL190W Hydrophilin essential in desiccation-rehydration process genetic 1 1 1 Synthetic Rescue
YJL193W YJL193W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
UBC7 YMR022W Ubiquitin conjugating enzyme genetic 1 1 1 Synthetic Rescue
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Synthetic Rescue
YIL060W YIL060W Mitochondrial protein of unknown function genetic 1 1 1 Synthetic Rescue
UBP12 YJL197W Ubiquitin-specific protease genetic 1 1 1 Synthetic Rescue
YIR016W YIR016W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Synthetic Rescue
YMR226C YMR226C NADP(+)-dependent serine dehydrogenase and carbonyl reductase genetic 1 1 1 Synthetic Rescue
YSA1 YBR111C Nudix hydrolase family member with ADP-ribose pyrophosphatase activity genetic 1 1 1 Synthetic Growth Defect
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Synthetic Growth Defect
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Synthetic Growth Defect
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Synthetic Growth Defect
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Synthetic Growth Defect
VIK1 YPL253C Protein that forms a kinesin-14 heterodimeric motor with Kar3p genetic 1 1 1 Synthetic Growth Defect
YGL081W YGL081W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YER084W YER084W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Synthetic Growth Defect
YPT7 YML001W Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Synthetic Growth Defect
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Synthetic Growth Defect
UBI4 YLL039C Ubiquitin genetic 1 1 1 Synthetic Growth Defect
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Synthetic Growth Defect
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Synthetic Rescue
YOR338W YOR338W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YEH2 YLR020C Steryl ester hydrolase genetic 1 1 1 Synthetic Growth Defect
ZRT2 YLR130C Low-affinity zinc transporter of the plasma membrane genetic 1 1 1 Synthetic Growth Defect
YDL211C YDL211C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YLR036C YLR036C Putative protein predicted to have transmembrane domains genetic 1 1 1 Synthetic Growth Defect
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
UBC11 YOR339C Ubiquitin-conjugating enzyme genetic 1 1 1 Synthetic Growth Defect
YTA6 YPL074W Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family genetic 1 1 1 Synthetic Growth Defect
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Synthetic Growth Defect
YDC1 YPL087W Alkaline dihydroceramidase, involved in sphingolipid metabolism genetic 1 1 1 Synthetic Growth Defect
YIG1 YPL201C Protein that interacts with glycerol 3-phosphatase genetic 1 1 1 Synthetic Growth Defect
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Synthetic Growth Defect
UBP16 YPL072W Deubiquitinating enzyme anchored to the outer mitochondrial membrane genetic 1 1 1 Synthetic Growth Defect
YOR289W YOR289W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ULA1 YPL003W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Synthetic Growth Defect
YPR148C YPR148C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YPL068C YPL068C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YOR365C YOR365C Putative protein involved in sphingolipid biosynthesis genetic 1 1 1 Synthetic Growth Defect
YDR042C YDR042C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YPL113C YPL113C Glyoxylate reductase genetic 1 1 1 Synthetic Growth Defect
WTM2 YOR229W Transcriptional modulator genetic 1 1 1 Synthetic Growth Defect
YOR385W YOR385W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YPL088W YPL088W Putative aryl alcohol dehydrogenase genetic 1 1 1 Synthetic Growth Defect
YPL257W YPL257W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YOL153C YOL153C Blocked reading frame, contains two in-frame stops in translation genetic 1 1 1 Synthetic Growth Defect
YEL023C YEL023C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
WHI3 YNL197C RNA binding protein that modulates mRNA stability genetic 1 1 1 Synthetic Growth Defect
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Synthetic Growth Defect
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Synthetic Growth Defect
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Synthetic Growth Defect
YPL071C YPL071C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
TYW1 YPL207W Iron-sulfur protein required for synthesis of wybutosine modified tRNA genetic 1 1 1 Synthetic Growth Defect
WSS1 YHR134W SUMO-ligase and SUMO-targeted metalloprotease genetic 1 1 1 Synthetic Growth Defect
YAP1802 YGR241C Protein of the AP180 family, involved in clathrin cage assembly genetic 1 1 1 Synthetic Growth Defect
YPL199C YPL199C Protein involved in nonstop mRNA decay genetic 1 1 1 Synthetic Growth Defect
VSB1 YGR125W Vacuolar membrane protein required for uptake and storage of arginine genetic 1 1 1 Synthetic Growth Defect
WTM1 YOR230W Transcriptional modulator genetic 1 1 1 Synthetic Growth Defect
YOR283W YOR283W Phosphatase with a broad substrate specificity genetic 1 1 1 Synthetic Growth Defect
YPL108W YPL108W Cytoplasmic protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YPR027C YPR027C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YOR268C YOR268C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ZEO1 YOL109W Peripheral membrane protein of the plasma membrane genetic 1 1 1 Synthetic Growth Defect
YPL216W YPL216W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
UIP4 YPL186C Protein that interacts with Ulp1p genetic 1 1 1 Synthetic Growth Defect
YPL191C YPL191C K48-specific deubiquitinating (DUB) enzyme genetic 1 1 1 Synthetic Growth Defect
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Synthetic Growth Defect
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif genetic 1 1 1 Synthetic Growth Defect
YOR296W YOR296W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YDR109C YDR109C D-ribulokinase genetic 1 1 1 Synthetic Growth Defect
USV1 YPL230W Putative transcription factor containing a C2H2 zinc finger genetic 1 1 1 Synthetic Growth Defect
YOR238W YOR238W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YMC1 YPR058W Secondary mitochondrial inner membrane glycine transporter genetic 1 1 1 Synthetic Growth Defect
YOP1 YPR028W Reticulon-interacting protein genetic 1 1 1 Synthetic Growth Defect
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Synthetic Growth Defect
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Growth Defect
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation genetic 1 1 1 Synthetic Rescue
DPH2 YKL191W Protein required for synthesis of diphthamide genetic 1 1 1 Synthetic Rescue
HRB1 YNL004W Poly(A+) RNA-binding protein genetic 1 1 1 Synthetic Rescue
PHO2 YDL106C Homeobox transcription factor genetic 1 1 1 Synthetic Rescue
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Synthetic Growth Defect
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Synthetic Lethality
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Negative Genetic
OST6 YML019W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Synthetic Growth Defect
MBF1 YOR298C-A Transcriptional coactivator genetic 1 1 1 Synthetic Growth Defect
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
TRS33 YOR115C Core component of TRAPP complexes I, II and IV genetic 1 1 1 Synthetic Rescue
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Synthetic Rescue
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
MSO1 YNR049C Lipid-interacting protein in SNARE complex assembly machinery genetic 1 1 1 Synthetic Rescue
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Synthetic Growth Defect
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Synthetic Growth Defect
ARG80 YMR042W Transcription factor involved in regulating arginine-responsive genes genetic 1 1 1 Synthetic Rescue
CHS3 YBR023C Chitin synthase III genetic 1 1 1 Negative Genetic
ESC1 YMR219W Protein involved in telomeric silencing genetic 1 1 1 Synthetic Rescue
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Synthetic Rescue
GNT1 YOR320C N-acetylglucosaminyltransferase genetic 1 1 1 Synthetic Growth Defect
DBP1 YPL119C ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Synthetic Growth Defect
DCN1 YLR128W Scaffold-type E3 ligase genetic 1 1 1 Synthetic Growth Defect
BCH1 YMR237W Member of the ChAPs family (Chs5p-Arf1p-binding proteins) genetic 1 1 1 Synthetic Rescue
EMA17 YIL029C Protein involved in targeting mitochondrial membrane protein precursor genetic 1 1 1 Synthetic Rescue
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Synthetic Rescue
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Growth Defect
PEX25 YPL112C Peripheral peroxisomal membrane peroxin genetic 1 1 1 Synthetic Growth Defect
PEX28 YHR150W Peroxisomal integral membrane peroxin genetic 1 1 1 Synthetic Rescue
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
CMR2 YOR093C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
RLM1 YPL089C MADS-box transcription factor genetic 1 1 1 Synthetic Growth Defect
ARK1 YNL020C Ser/Thr protein kinase genetic 1 1 1 Synthetic Rescue
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway genetic 1 1 1 Synthetic Growth Defect
SPA2 YLL021W Component of the polarisome genetic 1 1 1 Synthetic Growth Defect
SPC42 YKL042W Central plaque component of spindle pole body (SPB) physical 1 1 1 Affinity Capture-MS
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Synthetic Rescue
TEA1 YOR337W Ty1 enhancer activator involved in Ty enhancer-mediated transcription genetic 1 1 1 Synthetic Growth Defect
PEX27 YOR193W Peripheral peroxisomal membrane protein genetic 1 1 1 Synthetic Rescue
SAM2 YDR502C S-adenosylmethionine synthetase genetic 1 1 1 Synthetic Rescue
RPL1A YPL220W Ribosomal 60S subunit protein L1A genetic 1 1 1 Synthetic Growth Defect
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Synthetic Growth Defect
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body genetic 1 1 1 Synthetic Rescue
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Synthetic Growth Defect
NIP100 YPL174C Large subunit of the dynactin complex genetic 1 1 1 Synthetic Growth Defect
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly genetic 1 1 1 Synthetic Growth Defect
REV3 YPL167C Catalytic subunit of DNA polymerase zeta genetic 1 1 1 Synthetic Growth Defect
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 1 1 1 Synthetic Growth Defect
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) genetic 1 1 1 Synthetic Growth Defect
CCH1 YGR217W Voltage-gated high-affinity calcium channel genetic 1 1 1 Synthetic Rescue
KAR1 YNL188W Protein involved in karyogamy and spindle pole body duplication physical 1 1 1 Affinity Capture-Western
CQD1 YPL109C UbiB family mitochondrial protein genetic 1 1 1 Synthetic Growth Defect
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Synthetic Rescue
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Synthetic Growth Defect
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation genetic 1 1 1 Synthetic Rescue
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Rescue
COX17 YLL009C Copper metallochaperone that transfers copper to Sco1p and Cox11p genetic 1 1 1 Synthetic Growth Defect
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 1 1 1 Synthetic Rescue
HPA2 YPR193C Tetrameric histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Synthetic Growth Defect
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) genetic 1 1 1 Synthetic Rescue
ERV29 YGR284C Protein localized to COPII-coated vesicles genetic 1 1 1 Synthetic Rescue
REC8 YPR007C Meiosis-specific component of the sister chromatid cohesion complex genetic 1 1 1 Synthetic Growth Defect
PMT3 YOR321W Protein O-mannosyltransferase genetic 1 1 1 Synthetic Growth Defect
TCB1 YOR086C Lipid-binding ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Synthetic Rescue
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Synthetic Rescue
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway genetic 1 1 1 Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Rescue
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Synthetic Growth Defect
ENV11 YGR071C Protein proposed to be involved in vacuolar functions genetic 1 1 1 Synthetic Rescue
MNN14 YJR061W Protein required for N-glycan mannosylphosphorylation genetic 1 1 1 Synthetic Rescue
GSM1 YJL103C Putative zinc cluster protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MNT4 YNR059W Putative alpha-1,3-mannosyltransferase genetic 1 1 1 Synthetic Rescue
ENT5 YDR153C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Synthetic Rescue
KAP120 YPL125W Karyopherin responsible for the nuclear import of Rpf1p genetic 1 1 1 Synthetic Growth Defect
ASN1 YPR145W Asparagine synthetase genetic 1 1 1 Synthetic Growth Defect
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Synthetic Growth Defect
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Synthetic Rescue
HUB1 YNR032C-A Ubiquitin-like protein modifier genetic 1 1 1 Synthetic Rescue
COX14 YML129C Mitochondrial cytochrome c oxidase (complex IV) assembly factor genetic 1 1 1 Synthetic Growth Defect
CLB3 YDL155W B-type cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Growth Defect
STB5 YHR178W Transcription factor genetic 1 1 1 Synthetic Growth Defect
TUB1 YML085C Alpha-tubulin physical 1 1 1 Co-localization
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Synthetic Growth Defect
AQR1 YNL065W Plasma membrane transporter of the major facilitator superfamily genetic 1 1 1 Synthetic Growth Defect
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 genetic 1 1 1 Synthetic Rescue
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
PER33 YLR064W Protein that localizes to the endoplasmic reticulum genetic 1 1 1 Synthetic Growth Defect
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Synthetic Rescue
RPL13A YDL082W Ribosomal 60S subunit protein L13A genetic 1 1 1 Synthetic Rescue
MDM31 YHR194W Mitochondrial protein that may have a role in phospholipid metabolism genetic 1 1 1 Synthetic Growth Defect
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Synthetic Growth Defect
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 genetic 1 1 1 Synthetic Rescue
RPS0A YGR214W Ribosomal 40S subunit protein S0A genetic 1 1 1 Synthetic Rescue
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Synthetic Rescue
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Synthetic Growth Defect
MIT1 YEL007W Transcriptional regulator of pseudohyphal growth genetic 1 1 1 Synthetic Growth Defect
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Synthetic Growth Defect
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Negative Genetic
CRR1 YLR213C Putative glycoside hydrolase of the spore wall envelope genetic 1 1 1 Synthetic Growth Defect
REV1 YOR346W Deoxycytidyl transferase genetic 1 1 1 Synthetic Growth Defect
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Synthetic Rescue
ARO8 YGL202W Aromatic aminotransferase I genetic 1 1 1 Synthetic Rescue
SLK19 YOR195W Kinetochore-associated protein genetic 1 1 1 Synthetic Growth Defect
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Synthetic Rescue
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 1 1 1 Synthetic Growth Defect
KIP2 YPL155C Kinesin-related motor protein involved in mitotic spindle positioning genetic 1 1 1 Synthetic Lethality
RPL16B YNL069C Ribosomal 60S subunit protein L16B genetic 1 1 1 Synthetic Rescue
GPB1 YOR371C Multistep regulator of cAMP-PKA signaling genetic 1 1 1 Synthetic Growth Defect
GLR1 YPL091W Cytosolic and mitochondrial glutathione oxidoreductase genetic 1 1 1 Synthetic Growth Defect
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Synthetic Rescue
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Synthetic Rescue
ADE1 YAR015W N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase genetic 1 1 1 Synthetic Growth Defect
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Synthetic Growth Defect
FMO1 YHR176W Flavin-containing monooxygenase genetic 1 1 1 Synthetic Rescue
ATF1 YOR377W Alcohol acetyltransferase genetic 1 1 1 Synthetic Growth Defect
ARR3 YPR201W Plasma membrane metalloid/H+ antiporter genetic 1 1 1 Synthetic Growth Defect
DUS3 YLR401C Dihydrouridine synthase genetic 1 1 1 Negative Genetic
BCH2 YKR027W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Synthetic Rescue
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
NDJ1 YOL104C Protein that regulates meiotic SPB cohesion and telomere clustering genetic 1 1 1 Synthetic Rescue
SIA1 YOR137C Protein of unassigned function genetic 1 1 1 Synthetic Growth Defect
CAN1 YEL063C Plasma membrane arginine permease genetic 1 1 1 Synthetic Growth Defect
RMI1 YPL024W Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex genetic 1 1 1 Synthetic Growth Defect
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Synthetic Growth Defect
PAM17 YKR065C Constituent of the TIM23 complex genetic 1 1 1 Synthetic Rescue
MF(ALPHA)1 YPL187W Mating pheromone alpha-factor, made by alpha cells genetic 1 1 1 Synthetic Growth Defect
PYK2 YOR347C Pyruvate kinase genetic 1 1 1 Synthetic Growth Defect
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 1 1 1 Synthetic Rescue
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 1 1 1 Synthetic Growth Defect
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
NCE102 YPR149W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 1 1 1 Synthetic Growth Defect
TIP1 YBR067C Major cell wall mannoprotein with possible lipase activity genetic 1 1 1 Synthetic Growth Defect
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Synthetic Growth Defect
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B genetic 1 1 1 Synthetic Rescue
FRE3 YOR381W Ferric reductase genetic 1 1 1 Synthetic Growth Defect
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
PHR1 YOR386W DNA photolyase involved in photoreactivation genetic 1 1 1 Synthetic Growth Defect
DSE4 YNR067C Daughter cell-specific secreted protein with similarity to glucanases genetic 1 1 1 Synthetic Rescue
COQ10 YOL008W Coenzyme Q (ubiquinone) binding protein genetic 1 1 1 Synthetic Growth Defect
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex genetic 1 1 1 Synthetic Growth Defect
PIP2 YOR363C Autoregulatory, oleate-activated transcription factor genetic 1 1 1 Synthetic Growth Defect
NAT5 YOR253W Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
RAD34 YDR314C Protein involved in nucleotide excision repair (NER) genetic 1 1 1 Synthetic Rescue
PUF4 YGL014W Member of the PUF protein family genetic 1 1 1 Synthetic Rescue
STP1 YDR463W Transcription factor genetic 1 1 1 Synthetic Growth Defect
JIP4 YDR475C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Positive Genetic
COQ11 YLR290C Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes genetic 1 1 1 Synthetic Growth Defect
DDR48 YMR173W DNA damage-responsive protein genetic 1 1 1 Synthetic Rescue
HIS2 YFR025C Histidinolphosphatase genetic 1 1 1 Synthetic Growth Defect
ATG38 YLR211C Homodimeric subunit of autophagy-specific PtdIns-3-kinase complex I genetic 1 1 1 Synthetic Growth Defect
CUE3 YGL110C Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Synthetic Rescue
MET12 YPL023C Protein with MTHFR activity in vitro genetic 1 1 1 Synthetic Growth Defect
MPP6 YNR024W Nuclear exosome-associated RNA binding protein genetic 1 1 1 Synthetic Rescue
MVB12 YGR206W ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers genetic 1 1 1 Synthetic Rescue
IRC3 YDR332W Double-stranded DNA-dependent helicase of the DExH/D-box family genetic 1 1 1 Synthetic Growth Defect
BIO2 YGR286C Biotin synthase genetic 1 1 1 Synthetic Rescue
MRP35 YNL122C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Rescue
LYS14 YDR034C Transcriptional activator involved in regulating lysine biosynthesis genetic 1 1 1 Synthetic Growth Defect
NDT80 YHR124W Meiosis-specific transcription factor genetic 1 1 1 Synthetic Rescue
INA22 YIR024C F1F0 ATP synthase peripheral stalk assembly factor genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Synthetic Growth Defect
ALD6 YPL061W Cytosolic aldehyde dehydrogenase genetic 1 1 1 Synthetic Growth Defect
RTC4 YNL254C Protein of unknown function genetic 1 1 1 Synthetic Rescue
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Synthetic Growth Defect
IZH3 YLR023C Membrane protein involved in zinc ion homeostasis genetic 1 1 1 Synthetic Growth Defect
MUK1 YPL070W Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Growth Defect
CGI121 YML036W Component of the EKC/KEOPS complex genetic 1 1 1 Synthetic Rescue
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Synthetic Rescue
RPL37A YLR185W Ribosomal 60S subunit protein L37A genetic 1 1 1 Synthetic Rescue
KIN4 YOR233W Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Synthetic Growth Defect
INA17 YPL099C F1F0 ATPase synthase peripheral stalk assembly factor genetic 1 1 1 Synthetic Growth Defect
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Synthetic Rescue
RPS25B YLR333C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
MDM36 YPR083W Mitochondrial protein genetic 1 1 1 Negative Genetic
ECM3 YOR092W Non-essential protein of unknown function genetic 1 1 1 Synthetic Rescue
ANY1 YMR010W Protein involved in phospholipid flippase function genetic 1 1 1 Synthetic Rescue
HFD1 YMR110C Dehydrogenase involved in ubiquinone and sphingolipid metabolism genetic 1 1 1 Synthetic Growth Defect
RPL42A YNL162W Ribosomal 60S subunit protein L42A genetic 1 1 1 Synthetic Rescue
ERV2 YPR037C Flavin-linked sulfhydryl oxidase localized to the ER lumen genetic 1 1 1 Synthetic Growth Defect
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase genetic 1 1 1 Synthetic Growth Defect
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes genetic 1 1 1 Synthetic Rescue
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Synthetic Growth Defect
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 1 1 1 Synthetic Growth Defect
MRS2 YOR334W Mitochondrial inner membrane Mg(2+) channel genetic 1 1 1 Synthetic Growth Defect
ALD4 YOR374W Mitochondrial aldehyde dehydrogenase genetic 1 1 1 Synthetic Growth Defect
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 1 1 1 Synthetic Growth Defect
SYH1 YPL105C Protein of unknown function that influences nuclear pore distribution genetic 1 1 1 Synthetic Growth Defect
RDS2 YPL133C Transcription factor involved in regulating gluconeogenesis genetic 1 1 1 Synthetic Growth Defect
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Synthetic Growth Defect
PFK26 YIL107C 6-phosphofructo-2-kinase genetic 1 1 1 Synthetic Rescue
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
IDP3 YNL009W Peroxisomal NADP-dependent isocitrate dehydrogenase genetic 1 1 1 Synthetic Rescue
KRE28 YDR532C Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Synthetic Growth Defect
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Synthetic Rescue
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Synthetic Rescue
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Synthetic Growth Defect
MSS18 YPR134W Nuclear encoded protein needed for splicing of mitochondrial intron genetic 1 1 1 Synthetic Growth Defect
ARO3 YDR035W 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase genetic 1 1 1 Synthetic Growth Defect
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Synthetic Growth Defect
RPL24A YGL031C Ribosomal 60S subunit protein L24A genetic 1 1 1 Synthetic Rescue
SDD3 YOL098C Putative metalloprotease genetic 1 1 1 Synthetic Rescue
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
RPL7B YPL198W Ribosomal 60S subunit protein L7B genetic 1 1 1 Synthetic Growth Defect
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Synthetic Rescue
PMS1 YNL082W ATP-binding protein required for mismatch repair genetic 1 1 1 Synthetic Rescue
RTR1 YER139C Dual specificity protein phosphatase genetic 1 1 1 Synthetic Growth Defect
RPL17B YJL177W Ribosomal 60S subunit protein L17B genetic 1 1 1 Synthetic Rescue
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Synthetic Growth Defect
RPL6B YLR448W Ribosomal 60S subunit protein L6B genetic 1 1 1 Synthetic Rescue
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Synthetic Rescue
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 1 1 1 Synthetic Rescue
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Negative Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Synthetic Growth Defect
SQS1 YNL224C Protein that stimulates the ATPase and helicase activities of Prp43p genetic 1 1 1 Synthetic Rescue
GVP36 YIL041W BAR domain protein that localizes to early and late Golgi vesicles genetic 1 1 1 Synthetic Rescue
RPP2A YOL039W Ribosomal protein P2 alpha genetic 1 1 1 Synthetic Rescue
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 1 1 1 Synthetic Growth Defect
RPL36A YMR194W Ribosomal 60S subunit protein L36A genetic 1 1 1 Synthetic Rescue
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
RPL26A YLR344W Ribosomal 60S subunit protein L26A genetic 1 1 1 Synthetic Rescue
RPL34A YER056C-A Ribosomal 60S subunit protein L34A genetic 1 1 1 Synthetic Rescue
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
ABP140 YOR239W AdoMet-dependent tRNA methyltransferase and actin binding protein genetic 1 1 1 Synthetic Growth Defect
ATG21 YPL100W Phosphoinositide binding protein genetic 1 1 1 Synthetic Growth Defect
AIM29 YKR074W Protein of unknown function genetic 1 1 1 Synthetic Rescue
CMK2 YOL016C Calmodulin-dependent protein kinase physical 1 1 1 Reconstituted Complex
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Synthetic Growth Defect
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Synthetic Rescue
ARN2 YHL047C Transporter genetic 1 1 1 Synthetic Rescue
ABM1 YJR108W Protein of unknown function genetic 1 1 1 Synthetic Rescue
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Synthetic Rescue
IRC23 YOR044W Protein of unknown function involved in multidrug resistance genetic 1 1 1 Synthetic Rescue
AIM39 YOL053W Protein of unknown function genetic 1 1 1 Synthetic Rescue
HIS5 YIL116W Histidinol-phosphate aminotransferase genetic 1 1 1 Synthetic Growth Defect
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Synthetic Growth Defect
PUF2 YPR042C PUF family mRNA-binding protein genetic 1 1 1 Synthetic Growth Defect
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein genetic 1 1 1 Synthetic Growth Defect
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Synthetic Growth Defect
RNY1 YPL123C Vacuolar RNase of the T(2) family genetic 1 1 1 Synthetic Growth Defect
TMA22 YJR014W Protein of unknown function genetic 1 1 1 Synthetic Rescue
DIA1 YMR316W Protein of unknown function genetic 1 1 1 Synthetic Rescue
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Synthetic Growth Defect
LCL1 YPL056C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
TIP41 YPR040W Tap42p-interacting protein genetic 1 1 1 Synthetic Growth Defect
ECM7 YLR443W Putative integral membrane protein with a role in calcium uptake genetic 1 1 1 Synthetic Rescue
SIT1 YEL065W Ferrioxamine B transporter genetic 1 1 1 Synthetic Growth Defect
PNT1 YOR266W Mitochondrial integral inner membrane protein genetic 1 1 1 Synthetic Growth Defect
TOS4 YLR183C Putative transcription factor, contains Forkhead Associated domain genetic 1 1 1 Synthetic Growth Defect
SMF1 YOL122C Divalent metal ion transporter genetic 1 1 1 Synthetic Rescue
TRI1 YMR233W Non-essential sumoylated protein of unknown function genetic 1 1 1 Synthetic Rescue
RGS2 YOR107W Negative regulator of glucose-induced cAMP signaling genetic 1 1 1 Synthetic Rescue
RPS18B YML026C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
SGE1 YPR198W Plasma membrane multidrug transporter genetic 1 1 1 Synthetic Rescue
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Synthetic Growth Defect
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Synthetic Growth Defect
NRM1 YNR009W Transcriptional co-repressor of MBF-regulated gene expression genetic 1 1 1 Synthetic Rescue
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Synthetic Rescue
SNX3 YOR357C Sorting nexin for late-Golgi enzymes genetic 1 1 1 Synthetic Growth Defect
EST2 YLR318W Reverse transcriptase subunit of the telomerase holoenzyme genetic 1 1 1 Synthetic Rescue
ASI1 YMR119W Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Synthetic Growth Defect
OSW1 YOR255W Protein involved in sporulation genetic 1 1 1 Synthetic Growth Defect
RRT2 YBR246W Methylesterase performing penultimate step of diphthamide biosynthesis genetic 1 1 1 Synthetic Growth Defect
PEX31 YGR004W Peroxisomal integral membrane protein genetic 1 1 1 Synthetic Growth Defect
THR1 YHR025W Homoserine kinase genetic 1 1 1 Synthetic Growth Defect
APE4 YHR113W Cytoplasmic aspartyl aminopeptidase with possible vacuole function genetic 1 1 1 Synthetic Rescue
RSF1 YMR030W Protein required for respiratory growth genetic 1 1 1 Synthetic Rescue
COQ2 YNR041C Para hydroxybenzoate polyprenyl transferase genetic 1 1 1 Synthetic Growth Defect
RPP1B YDL130W Ribosomal protein P1 beta genetic 1 1 1 Synthetic Rescue
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Synthetic Growth Defect
PNC1 YGL037C Nicotinamidase that converts nicotinamide to nicotinic acid genetic 1 1 1 Synthetic Growth Defect
PNP1 YLR209C Purine nucleoside phosphorylase genetic 1 1 1 Synthetic Growth Defect
RDL1 YOR285W Thiosulfate sulfurtransferase genetic 1 1 1 Synthetic Growth Defect
EEB1 YPL095C Acyl-coenzymeA:ethanol O-acyltransferase genetic 1 1 1 Synthetic Growth Defect
SPO11 YHL022C Meiosis-specific protein required for meiotic recombination genetic 1 1 1 Negative Genetic
RCR2 YDR003W Vacuolar ubiquitin ligase-substrate adaptor genetic 1 1 1 Synthetic Growth Defect
NPR1 YNL183C Protein kinase genetic 1 1 1 Synthetic Growth Defect
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
ARF3 YOR094W Glucose-repressible ADP-ribosylation factor genetic 1 1 1 Synthetic Rescue
HXT2 YMR011W High-affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Synthetic Rescue
FRE1 YLR214W Ferric reductase and cupric reductase genetic 1 1 1 Synthetic Growth Defect
SUR7 YML052W Plasma membrane protein, component of eisosomes genetic 1 1 1 Synthetic Rescue
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 1 1 1 Synthetic Growth Defect
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Synthetic Growth Defect
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Synthetic Rescue
AIM34 YMR003W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
PRY1 YJL079C Lipid binding protein genetic 1 1 1 Synthetic Growth Defect
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Synthetic Growth Defect
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Synthetic Rescue
MET8 YBR213W Bifunctional dehydrogenase and ferrochelatase genetic 1 1 1 Synthetic Growth Defect
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Synthetic Growth Defect
FLC1 YPL221W Flavin adenine dinucleotide transporter genetic 1 1 1 Synthetic Growth Defect
DUR3 YHL016C Plasma membrane transporter for both urea and polyamines genetic 1 1 1 Synthetic Rescue
RBS1 YDL189W Protein involved in assembly of the RNA Pol III complex genetic 1 1 1 Synthetic Rescue
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Synthetic Growth Defect
SPO19 YPL130W Meiosis-specific prospore protein genetic 1 1 1 Synthetic Growth Defect
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Synthetic Rescue
PIN2 YOR104W Exomer-dependent cargo protein genetic 1 1 1 Synthetic Rescue
TPO4 YOR273C Polyamine transporter of the major facilitator superfamily genetic 1 1 1 Synthetic Growth Defect
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Synthetic Growth Defect
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER genetic 1 1 1 Synthetic Rescue
SHR5 YOL110W Palmitoyltransferase subunit genetic 1 1 1 Synthetic Growth Defect
DCW1 YKL046C Putative mannosidase genetic 1 1 1 Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Synthetic Rescue
ARO7 YPR060C Chorismate mutase genetic 1 1 1 Synthetic Growth Defect
SLM4 YBR077C Subunit of the EGO/GSE complex genetic 1 1 1 Synthetic Growth Defect
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Synthetic Growth Defect
FRT1 YOR324C Tail-anchored ER membrane protein of unknown function genetic 1 1 1 Synthetic Growth Defect
AMD2 YDR242W Putative amidase genetic 1 1 1 Synthetic Growth Defect
PXP1 YEL020C Peroxisomal matrix protein genetic 1 1 1 Synthetic Growth Defect
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase genetic 1 1 1 Synthetic Rescue
MLO127 YJR039W Mitochondrial protein of unknown function genetic 1 1 1 Synthetic Growth Defect
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 1 1 1 Synthetic Growth Defect
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Synthetic Growth Defect
HAL9 YOL089C Putative transcription factor containing a zinc finger genetic 1 1 1 Synthetic Rescue
CUR1 YPR158W Sorting factor, central regulator of spatial protein quality control genetic 1 1 1 Synthetic Growth Defect
DAT1 YML113W DNA binding protein that recognizes oligo(dA).oligo(dT) tracts genetic 1 1 1 Synthetic Rescue
AGA1 YNR044W Anchorage subunit of a-agglutinin of a-cells genetic 1 1 1 Synthetic Rescue
FRE5 YOR384W Putative ferric reductase with similarity to Fre2p genetic 1 1 1 Synthetic Growth Defect
FIT3 YOR383C Mannoprotein that is incorporated into the cell wall genetic 1 1 1 Synthetic Growth Defect
EMI1 YDR512C Non-essential protein of unknown function genetic 1 1 1 Synthetic Rescue
AFT2 YPL202C Iron-regulated transcriptional activator genetic 1 1 1 Synthetic Growth Defect
ATO2 YNR002C Putative transmembrane protein involved in export of ammonia genetic 1 1 1 Synthetic Rescue
ELO1 YJL196C Elongase I, medium-chain acyl elongase genetic 1 1 1 Synthetic Rescue
CSM4 YPL200W Protein required for accurate chromosome segregation during meiosis genetic 1 1 1 Synthetic Growth Defect
COX12 YLR038C Subunit VIb of cytochrome c oxidase genetic 1 1 1 Synthetic Growth Defect
CRT10 YOL063C Protein required for the degradation of mutant 25S rRNAs genetic 1 1 1 Synthetic Rescue
SLY41 YOR307C Protein involved in ER-to-Golgi transport genetic 1 1 1 Synthetic Rescue
OPT1 YJL212C Proton-coupled oligopeptide transporter of the plasma membrane genetic 1 1 1 Synthetic Rescue
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Synthetic Growth Defect
STP2 YHR006W Transcription factor genetic 1 1 1 Synthetic Rescue
PHA2 YNL316C Prephenate dehydratase genetic 1 1 1 Synthetic Growth Defect
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Growth Defect
SCW10 YMR305C Cell wall protein with similarity to glucanases genetic 1 1 1 Synthetic Rescue
SET6 YPL165C SET domain protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MTO1 YGL236C Mitochondrial protein genetic 1 1 1 Synthetic Growth Defect
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
GPM3 YOL056W Nonfunctional homolog of Gpm1p phosphoglycerate mutase genetic 1 1 1 Synthetic Rescue
ATH1 YPR026W Acid trehalase required for utilization of extracellular trehalose genetic 1 1 1 Synthetic Growth Defect
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Synthetic Rescue
HIS1 YER055C ATP phosphoribosyltransferase genetic 1 1 1 Synthetic Growth Defect
MAM3 YOL060C Protein involved in magnesium homeostasis genetic 1 1 1 Synthetic Rescue
ARN1 YHL040C ARN family transporter for siderophore-iron chelates genetic 1 1 1 Synthetic Rescue
SRL1 YOR247W Mannoprotein that exhibits a tight association with the cell wall genetic 1 1 1 Synthetic Growth Defect
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
MPC1 YGL080W Highly conserved subunit of mitochondrial pyruvate carrier (MPC) genetic 1 1 1 Synthetic Rescue
COX5B YIL111W Subunit Vb of cytochrome c oxidase genetic 1 1 1 Synthetic Growth Defect
DPC25 YPL107W Putative mitochondrial protein of unknown function genetic 1 1 1 Synthetic Growth Defect
FSH3 YOR280C Putative serine hydrolase genetic 1 1 1 Synthetic Growth Defect
MCP1 YOR228C Mitochondrial protein of unknown function involved in lipid homeostas genetic 1 1 1 Synthetic Growth Defect
MIC27 YNL100W Component of the MICOS complex genetic 1 1 1 Synthetic Rescue
ARR1 YPR199C Transcriptional activator of the basic leucine zipper (bZIP) family genetic 1 1 1 Synthetic Growth Defect
HPF1 YOL155C Haze-protective mannoprotein genetic 1 1 1 Synthetic Rescue
MZM1 YDR493W Protein required for assembly of the cytochrome bc(1) complex genetic 1 1 1 Synthetic Growth Defect
MPC2 YHR162W Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) genetic 1 1 1 Synthetic Rescue
DSC2 YOL073C Multi-transmembrane subunit of the DSC ubiquitin ligase complex genetic 1 1 1 Synthetic Growth Defect
LMO1 YLL007C Homolog of mammalian ELMO (Engulfment and celL MOtility) genetic 1 1 1 Synthetic Growth Defect
CYT2 YKL087C Cytochrome c1 heme lyase genetic 1 1 1 Synthetic Growth Defect
AGC1 YPR021C Mitochondrial amino acid transporter genetic 1 1 1 Synthetic Growth Defect
AIM20 YIL158W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
EFM4 YIL064W Lysine methyltransferase genetic 1 1 1 Synthetic Rescue
CPR8 YNR028W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Synthetic Rescue
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Synthetic Growth Defect
GSH2 YOL049W Glutathione synthetase genetic 1 1 1 Synthetic Rescue
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Synthetic Growth Defect
LDS2 YOL047C Protein Involved in spore wall assembly genetic 1 1 1 Synthetic Rescue
BIO5 YNR056C Putative transmembrane protein involved in the biotin biosynthesis genetic 1 1 1 Synthetic Rescue
MOD5 YOR274W Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase genetic 1 1 1 Synthetic Growth Defect
LDO16 YMR148W Protein of unknown function with possible role in spore wall assembly genetic 1 1 1 Synthetic Rescue
ALE1 YOR175C Broad-specificity lysophospholipid acyltransferase genetic 1 1 1 Synthetic Growth Defect
LEE1 YPL054W Zinc-finger protein of unknown function genetic 1 1 1 Synthetic Growth Defect
FMP30 YPL103C Protein with a role in maintaining mitochondrial morphology genetic 1 1 1 Synthetic Growth Defect
MIX14 YDR031W Mitochondrial intermembrane space protein of unknown function genetic 1 1 1 Synthetic Growth Defect
RPL24B YGR148C Ribosomal 60S subunit protein L24B genetic 1 1 1 Synthetic Rescue
REH1 YLR387C Cytoplasmic 60S subunit biogenesis factor genetic 1 1 1 Synthetic Growth Defect
ENB1 YOL158C Ferric enterobactin transmembrane transporter genetic 1 1 1 Synthetic Rescue
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Synthetic Rescue
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease genetic 1 1 1 Synthetic Growth Defect
ATR2 YMR279C Putative boron transporter involved in boron efflux and resistance genetic 1 1 1 Synthetic Rescue
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Synthetic Growth Defect
GUP2 YPL189W Probable membrane protein genetic 1 1 1 Synthetic Growth Defect
MNN1 YER001W Alpha-1,3-mannosyltransferase genetic 1 1 1 Synthetic Growth Defect
FLX1 YIL134W Mitochondrial flavin adenine dinucleotide transporter genetic 1 1 1 Synthetic Rescue
AQY1 YPR192W Spore-specific water channel genetic 1 1 1 Synthetic Growth Defect
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 1 1 1 Synthetic Growth Defect
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Synthetic Growth Defect
SMF2 YHR050W Divalent metal ion transporter involved in manganese homeostasis genetic 1 1 1 Synthetic Rescue
HXT8 YJL214W Protein of unknown function with similarity to hexose transporters genetic 1 1 1 Synthetic Rescue
CNE1 YAL058W Calnexin genetic 1 1 1 Synthetic Growth Defect
ODC1 YPL134C Mitochondrial inner membrane transporter genetic 1 1 1 Synthetic Growth Defect
HXT17 YNR072W Putative transmembrane polyol transporter genetic 1 1 1 Synthetic Growth Defect
ALG8 YOR067C Glucosyl transferase genetic 1 1 1 Synthetic Growth Defect
MFM1 YPL060W Mitochondrial inner membrane magnesium transporter genetic 1 1 1 Synthetic Growth Defect
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Synthetic Growth Defect
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Synthetic Rescue
PXP2 YJR111C Peroxisomal matrix protein with naturally active promoter genetic 1 1 1 Synthetic Rescue
PEX35 YGR168C Regulator of peroxisome abundance genetic 1 1 1 Synthetic Rescue
RPS30B YOR182C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
ARR2 YPR200C Arsenate reductase required for arsenate resistance genetic 1 1 1 Synthetic Growth Defect
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 1 1 1 Synthetic Growth Defect
NGL1 YOL042W Putative endonuclease genetic 1 1 1 Synthetic Rescue
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Synthetic Growth Defect
MFA1 YDR461W Mating pheromone a-factor genetic 1 1 1 Synthetic Growth Defect
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER genetic 1 1 1 Synthetic Rescue
PUS6 YGR169C tRNA:pseudouridine synthase genetic 1 1 1 Synthetic Rescue
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
RPS29A YLR388W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
SDH5 YOL071W Protein required for flavinylation of Sdh1p genetic 1 1 1 Synthetic Rescue
CSS3 YOL159C Protein of unknown function, secreted when constitutively expressed genetic 1 1 1 Synthetic Rescue
RPS28A YOR167C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
SCP1 YOR367W Component of yeast cortical actin cytoskeleton genetic 1 1 1 Synthetic Growth Defect
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Synthetic Growth Defect
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Synthetic Rescue
SFM1 YOR021C SPOUT methyltransferase genetic 1 1 1 Synthetic Rescue
HTC1 YPL067C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
PAN6 YIL145C Pantothenate synthase genetic 1 1 1 Synthetic Growth Defect
AIF1 YNR074C Mitochondrial cell death effector genetic 1 1 1 Synthetic Rescue
SPR3 YGR059W Sporulation-specific homolog of the CDC3/10/11/12 family of genes physical 1 1 1 Two-hybrid
SYM1 YLR251W Protein required for ethanol metabolism genetic 1 1 1 Synthetic Growth Defect
RKR1 YMR247C RING domain E3 ubiquitin ligase genetic 1 1 1 Synthetic Rescue
RPS30A YLR287C-A Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
MSC6 YOR354C Multicopy suppressor of HER2 involved in mitochondrial translation genetic 1 1 1 Synthetic Growth Defect
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Synthetic Growth Defect
PGC1 YPL206C Phosphatidylglycerol phospholipase C genetic 1 1 1 Synthetic Growth Defect
SIM1 YIL123W Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) genetic 1 1 1 Synthetic Rescue
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Synthetic Rescue
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Synthetic Growth Defect
SOL3 YHR163W 6-phosphogluconolactonase genetic 1 1 1 Synthetic Rescue
HPM1 YIL110W AdoMet-dependent methyltransferase genetic 1 1 1 Synthetic Rescue
SPE4 YLR146C Spermine synthase genetic 1 1 1 Synthetic Growth Defect
MRX11 YPL041C Protein that associates with mitochondrial ribosome genetic 1 1 1 Synthetic Growth Defect
OXR1 YPL196W Protein involved in regulation of vacuolar V-ATPase genetic 1 1 1 Synthetic Growth Defect
PRY3 YJL078C GPI-anchored cell wall protein involved in export of sterols genetic 1 1 1 Synthetic Rescue
SLH1 YGR271W Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Synthetic Rescue
MRX4 YPL168W Protein that associates with mitochondrial ribosome genetic 1 1 1 Synthetic Growth Defect
TMA16 YOR252W Protein of unknown function that associates with ribosomes genetic 1 1 1 Synthetic Growth Defect
FRE7 YOL152W Putative ferric reductase with similarity to Fre2p genetic 1 1 1 Synthetic Rescue
IRS4 YKR019C EH domain-containing protein genetic 1 1 1 Synthetic Growth Defect
FLO10 YKR102W Member of the FLO family of cell wall flocculation proteins genetic 1 1 1 Synthetic Rescue
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Synthetic Rescue
THI20 YOL055C Trifunctional enzyme of thiamine biosynthesis, degradation and salvage genetic 1 1 1 Synthetic Rescue
GRE1 YPL223C Hydrophilin essential in desiccation-rehydration process genetic 1 1 1 Synthetic Growth Defect
SPO22 YIL073C Meiosis-specific protein essential for chromosome synapsis genetic 1 1 1 Synthetic Rescue
TOM6 YOR045W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Synthetic Rescue
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 1 1 1 Synthetic Growth Defect
PAU23 YLR037C Cell wall mannoprotein genetic 1 1 1 Synthetic Growth Defect
HES1 YOR237W Protein implicated in the regulation of ergosterol biosynthesis genetic 1 1 1 Synthetic Growth Defect
MTC6 YHR151C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
TRM10 YOL093W tRNA methyltransferase genetic 1 1 1 Synthetic Rescue
ECM23 YPL021W Non-essential protein of unconfirmed function genetic 1 1 1 Synthetic Growth Defect
RTC5 YOR118W Protein of unknown function genetic 1 1 1 Synthetic Rescue
SRL4 YPL033C Protein of unknown function genetic 1 1 1 Synthetic Rescue
FYV12 YOR183W Protein of unknown function genetic 1 1 1 Synthetic Rescue
PAU4 YLR461W Member of the seripauperin multigene family genetic 1 1 1 Synthetic Rescue
RRT8 YOL048C Protein involved in spore wall assembly genetic 1 1 1 Synthetic Rescue
TPP1 YMR156C DNA 3'-phosphatase genetic 1 1 1 Synthetic Rescue
RCH1 YMR034C Negative regulator of cytosolic calcium homeostasis genetic 1 1 1 Synthetic Rescue
SPR2 YOR214C Putative spore wall protein genetic 1 1 1 Synthetic Growth Defect
TRP4 YDR354W Anthranilate phosphoribosyl transferase genetic 1 1 1 Synthetic Growth Defect
TDA6 YPR157W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 1 1 1 Negative Genetic
SHH3 YMR118C Putative mitochondrial inner membrane protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SSU1 YPL092W Plasma membrane sulfite pump involved in sulfite metabolism genetic 1 1 1 Synthetic Growth Defect
TFB6 YOR352W Subunit of TFIIH complex genetic 1 1 1 Synthetic Growth Defect
MTC7 YEL033W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect