Standard name Systematic name Name description Description
LSM6 YDR378C Lsm (Like Sm) protein Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA
Visualize the interactome of LSM6
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
LSM6 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
LSM1 YJL124C Lsm (Like Sm) protein physical 14 4 11 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Co-purification
LSM3 YLR438C-A Lsm (Like Sm) protein physical 9 4 8 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Affinity Capture-Western
LSM4 YER112W Lsm (Like Sm) protein physical 9 4 6 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA
LSM8 YJR022W Lsm (Like Sm) protein physical 8 3 6 Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS, PCA
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 7 4 7 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
LSM7 YNL147W Lsm (Like Sm) protein physical 7 3 5 Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Co-localization
LSM2 YBL026W Lsm (Like Sm) protein physical 7 3 5 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) physical 6 3 6 Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
LSM5 YER146W Lsm (Like Sm) protein physical 6 2 5 Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid
HIR1 YBL008W Subunit of the HIR complex genetic 6 2 5 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 6 2 5 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 6 1 5 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
YPT6 YLR262C Rab family GTPase genetic 6 1 5 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 6 2 4 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling physical 5 4 5 Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-RNA, Affinity Capture-Western
TOP1 YOL006C Topoisomerase I genetic 5 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 5 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality
ELP3 YPL086C Subunit of Elongator complex genetic 5 2 4 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 4 3 4 Affinity Capture-MS, PCA, Affinity Capture-MS, Affinity Capture-RNA
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 4 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SAC3 YDR159W mRNA export factor genetic 4 2 3 Negative Genetic, Positive Genetic, Negative Genetic, Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 4 2 3 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA genetic 4 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 4 2 3 Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
PRP3 YDR473C Splicing factor physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP31 YGR091W Splicing factor physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWC3 YAL011W Protein of unknown function genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
REX2 YLR059C 3'-5' RNA exonuclease genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 3 2 3 Positive Genetic, Negative Genetic, Positive Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 3 2 3 Positive Genetic, Negative Genetic, Positive Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
THI6 YPL214C Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Positive Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
PFY1 YOR122C Profilin genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 3 2 2 Positive Genetic, Negative Genetic, Positive Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 3 2 2 Positive Genetic, Positive Genetic, Negative Genetic
PRP31 YGR091W Splicing factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PRP4 YPR178W Splicing factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
REC104 YHR157W Protein involved in early stages of meiotic recombination genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SMM1 YNR015W Dihydrouridine synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC45 YLR103C DNA replication initiation factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LIN1 YHR156C Non-essential component of U5 snRNP genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
AIM22 YJL046W Lipoate-protein ligase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC73 YLR418C Component of the Paf1p complex genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
LEO1 YOR123C Component of the Paf1 complex genetic 2 2 2 Negative Genetic, Positive Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 physical 2 2 2 Two-hybrid, Affinity Capture-MS
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 2 2 2 Negative Genetic, Positive Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 2 2 Negative Genetic, Positive Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
CHS5 YLR330W Component of the exomer complex genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 2 1 2 Negative Genetic, Negative Genetic
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
ECM2 YBR065C Pre-mRNA splicing factor genetic 2 1 2 Negative Genetic, Negative Genetic
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 2 1 2 Negative Genetic, Negative Genetic
PRP4 YPR178W Splicing factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP6 YBR055C Splicing factor genetic 2 1 2 Negative Genetic, Negative Genetic
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 2 1 2 Negative Genetic, Negative Genetic
MFT1 YML062C Subunit of the THO complex genetic 2 1 2 Negative Genetic, Negative Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 2 1 2 Negative Genetic, Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 2 1 2 Negative Genetic, Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
SSD1 YDR293C Translational repressor genetic 2 1 2 Negative Genetic, Negative Genetic
SRC1 YML034W Inner nuclear membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) genetic 2 1 2 Negative Genetic, Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 2 1 2 Negative Genetic, Negative Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 2 1 2 Positive Genetic, Positive Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 2 1 2 Positive Genetic, Positive Genetic
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 2 1 2 Negative Genetic, Negative Genetic
PML1 YLR016C Subunit of the RES complex genetic 2 1 2 Negative Genetic, Negative Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 2 1 2 Negative Genetic, Negative Genetic
SLM4 YBR077C Subunit of the EGO/GSE complex genetic 2 1 2 Positive Genetic, Positive Genetic
TFC1 YBR123C Subunit of RNA polymerase III transcription initiation factor complex genetic 2 1 2 Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
RPL13A YDL082W Ribosomal 60S subunit protein L13A genetic 2 1 2 Negative Genetic, Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 2 1 2 Negative Genetic, Negative Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 2 1 2 Negative Genetic, Negative Genetic
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity genetic 2 1 2 Negative Genetic, Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 2 1 2 Negative Genetic, Negative Genetic
REE1 YJL217W Cytoplasmic protein involved in the regulation of enolase (ENO1) genetic 2 1 2 Negative Genetic, Negative Genetic
SSC1 YJR045C Hsp70 family ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 2 1 2 Negative Genetic, Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 2 1 2 Positive Genetic, Positive Genetic
NFU1 YKL040C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 2 1 2 Negative Genetic, Negative Genetic
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 2 1 2 Negative Genetic, Negative Genetic
SFH1 YLR321C Component of the RSC chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 2 1 2 Negative Genetic, Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 2 1 2 Negative Genetic, Negative Genetic
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 2 1 2 Negative Genetic, Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 2 1 2 Positive Genetic, Positive Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 2 1 2 Negative Genetic, Negative Genetic
RAS2 YNL098C GTP-binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 2 1 2 Negative Genetic, Negative Genetic
RPO31 YOR116C RNA polymerase III largest subunit C160 genetic 2 1 2 Negative Genetic, Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 2 1 2 Negative Genetic, Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex genetic 2 1 2 Negative Genetic, Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 2 1 2 Negative Genetic, Negative Genetic
STB5 YHR178W Transcription factor genetic 2 1 2 Positive Genetic, Positive Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 2 1 2 Negative Genetic, Negative Genetic
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP genetic 2 1 2 Negative Genetic, Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 2 Negative Genetic, Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 2 1 2 Negative Genetic, Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 2 1 2 Negative Genetic, Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 2 1 2 Negative Genetic, Negative Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 2 1 2 Negative Genetic, Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 2 1 2 Negative Genetic, Negative Genetic
ABD1 YBR236C Methyltransferase genetic 2 1 2 Positive Genetic, Positive Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 2 1 2 Negative Genetic, Negative Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 2 1 2 Negative Genetic, Negative Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 2 1 2 Negative Genetic, Negative Genetic
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 2 1 2 Negative Genetic, Negative Genetic
ATP11 YNL315C Molecular chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 2 1 2 Positive Genetic, Positive Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 2 Negative Genetic, Negative Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 2 1 2 Negative Genetic, Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 2 1 2 Negative Genetic, Negative Genetic
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 2 1 2 Negative Genetic, Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 2 1 2 Negative Genetic, Negative Genetic
KGD2 YDR148C Dihydrolipoyl transsuccinylase genetic 2 1 2 Negative Genetic, Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 2 1 2 Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Positive Genetic, Positive Genetic
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 2 1 2 Negative Genetic, Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 1 2 Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) genetic 2 1 2 Negative Genetic, Negative Genetic
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 2 1 2 Negative Genetic, Negative Genetic
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 2 1 2 Negative Genetic, Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 2 1 2 Negative Genetic, Negative Genetic
DAL82 YNL314W Positive regulator of allophanate inducible genes genetic 2 1 2 Negative Genetic, Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 2 1 2 Negative Genetic, Negative Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 2 1 2 Negative Genetic, Negative Genetic
ATC1 YDR184C Nuclear protein genetic 2 1 2 Negative Genetic, Negative Genetic
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 2 1 2 Negative Genetic, Negative Genetic
ATP12 YJL180C Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase genetic 2 1 2 Negative Genetic, Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites genetic 2 1 2 Negative Genetic, Negative Genetic
JID1 YPR061C Probable Hsp40p co-chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
DPH5 YLR172C Methyltransferase required for synthesis of diphthamide genetic 2 1 2 Negative Genetic, Negative Genetic
DER1 YBR201W ER membrane protein that promotes export of misfolded polypeptides genetic 2 1 2 Negative Genetic, Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 2 1 2 Negative Genetic, Negative Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 2 1 2 Negative Genetic, Negative Genetic
GYP8 YFL027C GTPase-activating protein for yeast Rab family members genetic 2 1 2 Negative Genetic, Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 2 1 2 Positive Genetic, Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 2 1 Positive Genetic, Negative Genetic
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 2 2 1 Negative Genetic, Positive Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 2 2 1 Negative Genetic, Positive Genetic
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 2 1 1 Negative Genetic, Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RTC6 YPL183W-A Protein involved in translation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 2 1 1 Positive Genetic, Positive Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 2 1 1 Positive Genetic, Positive Genetic
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export genetic 2 1 1 Negative Genetic, Negative Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 2 1 1 Negative Genetic, Negative Genetic
NUM1 YDR150W Protein required for nuclear migration genetic 2 1 1 Negative Genetic, Negative Genetic
SYF2 YGR129W Member of the NineTeen Complex (NTC) genetic 2 1 1 Negative Genetic, Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 2 1 1 Negative Genetic, Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 2 1 1 Negative Genetic, Negative Genetic
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit genetic 2 1 1 Negative Genetic, Negative Genetic
VPS68 YOL129W Vacuolar membrane protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome genetic 2 1 1 Negative Genetic, Negative Genetic
MRS2 YOR334W Mitochondrial inner membrane Mg(2+) channel genetic 2 1 1 Negative Genetic, Negative Genetic
URN1 YPR152C Protein of unknown function containing WW and FF domains genetic 2 1 1 Negative Genetic, Negative Genetic
MET16 YPR167C 3'-phosphoadenylsulfate reductase genetic 2 1 1 Negative Genetic, Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 2 1 1 Negative Genetic, Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 2 1 1 Negative Genetic, Negative Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 2 1 1 Negative Genetic, Negative Genetic
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 2 1 1 Negative Genetic, Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 1 Negative Genetic, Negative Genetic
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 2 1 1 Negative Genetic, Negative Genetic
BUD13 YGL174W Subunit of the RES complex genetic 2 1 1 Negative Genetic, Negative Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 2 1 1 Negative Genetic, Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 2 1 1 Negative Genetic, Negative Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 2 1 1 Negative Genetic, Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 2 1 1 Negative Genetic, Negative Genetic
JNM1 YMR294W Component of the yeast dynactin complex genetic 2 1 1 Negative Genetic, Negative Genetic
GPB2 YAL056W Multistep regulator of cAMP-PKA signaling genetic 2 1 1 Negative Genetic, Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 2 1 1 Negative Genetic, Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 2 1 1 Negative Genetic, Negative Genetic
BER1 YLR412W Protein involved in microtubule-related processes genetic 2 1 1 Negative Genetic, Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RSF2 YJR127C Zinc-finger protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CLF1 YLR117C Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 1 1 1 Negative Genetic
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 1 1 1 Negative Genetic
AIM25 YJR100C Mitochondria protein of unknown function genetic 1 1 1 Negative Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
KAP123 YER110C Karyopherin beta genetic 1 1 1 Negative Genetic
KRE29 YER038C Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family genetic 1 1 1 Positive Genetic
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex genetic 1 1 1 Negative Genetic
HCA4 YJL033W DEAD box RNA helicase genetic 1 1 1 Negative Genetic
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex genetic 1 1 1 Positive Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
YLR053C YLR053C Putative protein of unknown function physical 1 1 1 Two-hybrid
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
YUR1 YJL139C Mannosyltransferase involved in protein N-glycosylation physical 1 1 1 Two-hybrid
PRP19 YLL036C Splicing factor associated with the spliceosome physical 1 1 1 Co-purification
PRP2 YNR011C RNA-dependent DExD/H-box ATPase physical 1 1 1 Affinity Capture-MS
PRP6 YBR055C Splicing factor physical 1 1 1 Affinity Capture-MS
RSE1 YML049C Protein involved in pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
SMD3 YLR147C Core Sm protein Sm D3 physical 1 1 1 Affinity Capture-MS
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 1 1 1 Affinity Capture-MS
MFA2 YNL145W Mating pheromone a-factor physical 1 1 1 Protein-RNA
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 Protein-RNA
RPL41A YDL184C Ribosomal 60S subunit protein L41A physical 1 1 1 Protein-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
SMB1 YER029C Core Sm protein Sm B physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family genetic 1 1 1 Negative Genetic
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Negative Genetic
NMD4 YLR363C Protein that may be involved in nonsense-mediated mRNA decay physical 1 1 1 Affinity Capture-MS
STL1 YDR536W Glycerol proton symporter of the plasma membrane physical 1 1 1 Affinity Capture-RNA
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains physical 1 1 1 Affinity Capture-MS
NPL6 YMR091C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
THP1 YOL072W Nuclear pore-associated protein genetic 1 1 1 Negative Genetic
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
SKA1 YKL023W SKI complex-associated protein genetic 1 1 1 Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Negative Genetic
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Negative Genetic
PSY3 YLR376C Component of Shu complex (aka PCSS complex) genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
RDH54 YBR073W DNA-dependent ATPase genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
RBH1 YJL181W Putative protein of unknown function genetic 1 1 1 Negative Genetic
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Negative Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 1 1 1 Negative Genetic
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Negative Genetic
RAD24 YER173W Checkpoint protein genetic 1 1 1 Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Negative Genetic
SPT23 YKL020C ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Negative Genetic
SAS4 YDR181C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 1 1 1 Negative Genetic
MED2 YDL005C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
VPS75 YNL246W NAP family histone chaperone genetic 1 1 1 Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Negative Genetic
RPN13 YLR421C Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Negative Genetic
NHP6B YBR089C-A High-mobility group (HMG) protein genetic 1 1 1 Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Positive Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Positive Genetic
RAD3 YER171W 5' to 3' DNA helicase genetic 1 1 1 Positive Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Positive Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Positive Genetic
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Positive Genetic
WHI4 YDL224C Putative RNA binding protein genetic 1 1 1 Positive Genetic
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Positive Genetic
SCY1 YGL083W Putative kinase genetic 1 1 1 Negative Genetic
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Positive Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Negative Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Positive Genetic
YCH1 YGR203W Phosphatase with sequence similarity to Mih1p genetic 1 1 1 Negative Genetic
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 1 1 1 Positive Genetic
TUB3 YML124C Alpha-tubulin genetic 1 1 1 Negative Genetic
TEP1 YNL128W PTEN homolog with no demonstrated inositol lipid phosphatase activity genetic 1 1 1 Negative Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Negative Genetic
YIH1 YCR059C Negative regulator of eIF2 kinase Gcn2p genetic 1 1 1 Negative Genetic
SRF1 YDL133W Regulator of phospholipase D (Spo14p) genetic 1 1 1 Negative Genetic
PRP28 YDR243C Pre-mRNA splicing factor genetic 1 1 1 Negative Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 1 1 1 Negative Genetic
ROM1 YGR070W Guanine nucleotide exchange factor (GEF) for Rho1p genetic 1 1 1 Negative Genetic
UTP22 YGR090W Component of the small-subunit processome genetic 1 1 1 Negative Genetic
MMF1 YIL051C Mitochondrial protein required for transamination of isoleucine genetic 1 1 1 Negative Genetic
MBR1 YKL093W Protein involved in mitochondrial functions and stress response genetic 1 1 1 Negative Genetic
YKR018C YKR018C Protein of unknown function genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
PAU4 YLR461W Member of the seripauperin multigene family genetic 1 1 1 Negative Genetic
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Positive Genetic
NCR1 YPL006W Vacuolar membrane protein involved with Npc2p in sterol trafficking genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Synthetic Growth Defect
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Lethality
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Growth Defect
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Synthetic Growth Defect
RAD51 YER095W Strand exchange protein genetic 1 1 1 Synthetic Growth Defect
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Synthetic Growth Defect
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 1 1 1 Synthetic Growth Defect
RAD55 YDR076W Protein that stimulates strand exchange genetic 1 1 1 Synthetic Growth Defect
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Synthetic Growth Defect
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Synthetic Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation genetic 1 1 1 Synthetic Rescue
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Synthetic Growth Defect
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Synthetic Growth Defect
RPB5 YBR154C RNA polymerase subunit ABC27 genetic 1 1 1 Positive Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
RRP43 YCR035C Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Positive Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Positive Genetic
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family genetic 1 1 1 Positive Genetic
MTR3 YGR158C Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
THS1 YIL078W Threonyl-tRNA synthetase genetic 1 1 1 Positive Genetic
RFA3 YJL173C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Positive Genetic
TAH11 YJR046W DNA replication licensing factor genetic 1 1 1 Positive Genetic
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit genetic 1 1 1 Positive Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Positive Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Positive Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Positive Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
LTO1 YNL260C Substrate-specific adaptor protein involved in apo-Rli1p maturation genetic 1 1 1 Positive Genetic
RPB11 YOL005C RNA polymerase II subunit B12.5 genetic 1 1 1 Positive Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Positive Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Positive Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Positive Genetic
NGR1 YBR212W RNA binding protein that negatively regulates growth rate genetic 1 1 1 Positive Genetic
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Positive Genetic
PER1 YCR044C Protein of the endoplasmic reticulum genetic 1 1 1 Positive Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Positive Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 1 1 1 Positive Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Positive Genetic
RSA3 YLR221C Protein with a likely role in ribosomal maturation genetic 1 1 1 Positive Genetic
YLR297W YLR297W Protein of unknown function genetic 1 1 1 Positive Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Positive Genetic
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Positive Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Positive Genetic
YHM2 YMR241W Citrate and oxoglutarate carrier protein genetic 1 1 1 Positive Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Positive Genetic
MPP6 YNR024W Nuclear exosome-associated RNA binding protein genetic 1 1 1 Positive Genetic
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor genetic 1 1 1 Positive Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Positive Genetic
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein genetic 1 1 1 Positive Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Positive Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Positive Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Positive Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Positive Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Positive Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Positive Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Positive Genetic
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 1 1 1 Positive Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Positive Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Positive Genetic
YNL190W YNL190W Hydrophilin essential in desiccation-rehydration process genetic 1 1 1 Positive Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Positive Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Positive Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Positive Genetic
TFC3 YAL001C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Negative Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
POP4 YBR257W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
SCM3 YDL139C Nonhistone component of centromeric chromatin genetic 1 1 1 Negative Genetic
RPC11 YDR045C RNA polymerase III subunit C11 genetic 1 1 1 Negative Genetic
PDS1 YDR113C Securin genetic 1 1 1 Negative Genetic
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
TAM41 YGR046W Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase) genetic 1 1 1 Negative Genetic
TFC4 YGR047C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
TFG1 YGR186W TFIIF (Transcription Factor II) largest subunit genetic 1 1 1 Negative Genetic
YHR020W YHR020W Prolyl-tRNA synthetase genetic 1 1 1 Negative Genetic
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation genetic 1 1 1 Negative Genetic
PRP40 YKL012W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
TFA1 YKL028W TFIIE large subunit genetic 1 1 1 Negative Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p genetic 1 1 1 Negative Genetic
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
MAS1 YLR163C Beta subunit of the mitochondrial processing protease (MPP) genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
PRP39 YML046W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
PRE8 YML092C Alpha 2 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
TAF7 YMR227C TFIID subunit (67 kDa) genetic 1 1 1 Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex genetic 1 1 1 Negative Genetic
TOP2 YNL088W Topoisomerase II genetic 1 1 1 Negative Genetic
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Negative Genetic
ORC5 YNL261W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
TIM50 YPL063W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
TFB2 YPL122C Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
SPC29 YPL124W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Negative Genetic
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Negative Genetic
SUI3 YPL237W Beta subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
TAF11 YML015C TFIID subunit (40 kDa) genetic 1 1 1 Negative Genetic
ORC1 YML065W Largest subunit of the origin recognition complex genetic 1 1 1 Negative Genetic
TAF4 YMR005W TFIID subunit (48 kDa) genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Negative Genetic
TBF1 YPL128C Telobox-containing general regulatory factor genetic 1 1 1 Negative Genetic
SYN8 YAL014C Endosomal SNARE related to mammalian syntaxin 8 genetic 1 1 1 Negative Genetic
YBL008W-A YBL008W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL4A YBR031W Ribosomal 60S subunit protein L4A genetic 1 1 1 Negative Genetic
SCO1 YBR037C Copper-binding protein of mitochondrial inner membrane genetic 1 1 1 Negative Genetic
RPL19A YBR084C-A Ribosomal 60S subunit protein L19A genetic 1 1 1 Negative Genetic
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase genetic 1 1 1 Negative Genetic
RAD16 YBR114W Nucleotide excision repair (NER) protein genetic 1 1 1 Negative Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Negative Genetic
PEX32 YBR168W Peroxisomal integral membrane protein genetic 1 1 1 Negative Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Negative Genetic
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
VBA3 YCL069W Permease of basic amino acids in the vacuolar membrane genetic 1 1 1 Negative Genetic
SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PHO2 YDL106C Homeobox transcription factor genetic 1 1 1 Negative Genetic
MRPL11 YDL202W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
TFB5 YDR079C-A Component of RNA polymerase II general transcription factor TFIIH genetic 1 1 1 Negative Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Negative Genetic
MRX16 YDR132C Protein that associates with the large mitoribosomal subunit genetic 1 1 1 Negative Genetic
PEX7 YDR142C Peroxisomal signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
SDH4 YDR178W Membrane anchor subunit of succinate dehydrogenase (SDH) genetic 1 1 1 Negative Genetic
REF2 YDR195W RNA-binding protein genetic 1 1 1 Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport genetic 1 1 1 Negative Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
YBL081W YBL081W Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
YPK3 YBR028C AGC kinase genetic 1 1 1 Negative Genetic
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 1 1 1 Negative Genetic
NTC20 YBR188C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
YCL002C YCL002C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
VBA4 YDR119W Protein of unknown function genetic 1 1 1 Negative Genetic
MSH4 YFL003C Protein involved in meiotic recombination genetic 1 1 1 Negative Genetic
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
MPC3 YGR243W Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) genetic 1 1 1 Negative Genetic
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Negative Genetic
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Negative Genetic
NCE101 YJL205C Protein of unknown function genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
RPL37A YLR185W Ribosomal 60S subunit protein L37A genetic 1 1 1 Negative Genetic
NDL1 YLR254C Homolog of nuclear distribution factor NudE genetic 1 1 1 Negative Genetic
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Negative Genetic
YLR345W YLR345W Similar to 6-phosphofructo-2-kinase enzymes genetic 1 1 1 Negative Genetic
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Negative Genetic
REC114 YMR133W Protein involved in early stages of meiotic recombination genetic 1 1 1 Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 1 1 1 Negative Genetic
YMR265C YMR265C Putative protein of unknown function genetic 1 1 1 Negative Genetic
MTQ1 YNL063W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Negative Genetic
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p genetic 1 1 1 Negative Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
RRT8 YOL048C Protein involved in spore wall assembly genetic 1 1 1 Negative Genetic
SDH5 YOL071W Protein required for flavinylation of Sdh1p genetic 1 1 1 Negative Genetic
TRM11 YOL124C Catalytic subunit of adoMet-dependent tRNA methyltransferase complex genetic 1 1 1 Negative Genetic
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Negative Genetic
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
YPL068C YPL068C Protein of unknown function genetic 1 1 1 Negative Genetic
PCL8 YPL219W Cyclin genetic 1 1 1 Negative Genetic
PXP1 YEL020C Peroxisomal matrix protein genetic 1 1 1 Negative Genetic
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
RPS8B YER102W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS26B YER131W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
OXA1 YER154W Mitochondrial inner membrane insertase genetic 1 1 1 Negative Genetic
RRT5 YFR032C Putative protein of unknown function genetic 1 1 1 Negative Genetic
PUF4 YGL014W Member of the PUF protein family genetic 1 1 1 Negative Genetic
SDS23 YGL056C Protein involved in cell separation during budding genetic 1 1 1 Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TIM21 YGR033C Nonessential component of the TIM23 complex genetic 1 1 1 Negative Genetic
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YGR161W-C YGR161W-C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Negative Genetic
OTU2 YHL013C Protein of unknown function genetic 1 1 1 Negative Genetic
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
RPL42B YHR141C Ribosomal 60S subunit protein L42B genetic 1 1 1 Negative Genetic
MRPL6 YHR147C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MDM31 YHR194W Mitochondrial protein that may have a role in phospholipid metabolism genetic 1 1 1 Negative Genetic
MAM33 YIL070C Acidic protein of the mitochondrial matrix genetic 1 1 1 Negative Genetic
OSM1 YJR051W Fumarate reductase, catalyzes the reduction of fumarate to succinate genetic 1 1 1 Negative Genetic
YJR120W YJR120W Protein of unknown function genetic 1 1 1 Negative Genetic
YPT52 YKR014C Endosomal Rab family GTPase genetic 1 1 1 Negative Genetic
YKR075C YKR075C Protein of unknown function genetic 1 1 1 Negative Genetic
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 1 1 1 Negative Genetic
YLL056C YLL056C NADH-dependent aldehyde reductase genetic 1 1 1 Negative Genetic
YEH2 YLR020C Steryl ester hydrolase genetic 1 1 1 Negative Genetic
MLH2 YLR035C Protein involved in mismatch repair and meiotic recombination genetic 1 1 1 Negative Genetic
NHA1 YLR138W Na+/H+ antiporter genetic 1 1 1 Negative Genetic
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
RPL26A YLR344W Ribosomal 60S subunit protein L26A genetic 1 1 1 Negative Genetic
VAC14 YLR386W Enzyme regulator genetic 1 1 1 Negative Genetic
MRPL39 YML009C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
YML054C-A YML054C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Negative Genetic
RPL6A YML073C Ribosomal 60S subunit protein L6A genetic 1 1 1 Negative Genetic
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
YMR155W YMR155W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Negative Genetic
MRP7 YNL005C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
RPL16B YNL069C Ribosomal 60S subunit protein L16B genetic 1 1 1 Negative Genetic
MRP35 YNL122C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
PEX17 YNL214W Membrane peroxin of the peroxisomal importomer complex genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway genetic 1 1 1 Negative Genetic
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Negative Genetic
MRPS12 YNR036C Mitochondrial protein genetic 1 1 1 Negative Genetic
PET494 YNR045W Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Negative Genetic
MDM20 YOL076W Non-catalytic subunit of the NatB N-terminal acetyltransferase genetic 1 1 1 Negative Genetic
YOR034C-A YOR034C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SER1 YOR184W 3-phosphoserine aminotransferase genetic 1 1 1 Negative Genetic
RPL33B YOR234C Ribosomal 60S subunit protein L33B genetic 1 1 1 Negative Genetic
RFM1 YOR279C Component of the Sum1p-Rfm1p-Hst1p complex genetic 1 1 1 Negative Genetic
RAD17 YOR368W Checkpoint protein genetic 1 1 1 Negative Genetic
MFM1 YPL060W Mitochondrial inner membrane magnesium transporter genetic 1 1 1 Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SPO19 YPL130W Meiosis-specific prospore protein genetic 1 1 1 Negative Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 1 1 1 Negative Genetic
PET20 YPL159C Mitochondrial protein genetic 1 1 1 Negative Genetic
MRX4 YPL168W Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Negative Genetic
ROX1 YPR065W Heme-dependent repressor of hypoxic genes genetic 1 1 1 Negative Genetic
TKL1 YPR074C Transketolase genetic 1 1 1 Negative Genetic
YPR084W YPR084W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SMT1 YJL147C Translational repressor of the mitochondrial ATP6/8 mRNA genetic 1 1 1 Negative Genetic
SNL1 YIL016W Ribosome-associated protein genetic 1 1 1 Negative Genetic
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 1 1 1 Positive Genetic
QDR3 YBR043C Multidrug transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
PEX12 YMR026C C3HC4-type RING-finger peroxin and E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
PPR1 YLR014C Zinc finger transcription factor genetic 1 1 1 Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 1 1 1 Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Positive Genetic
PRR1 YKL116C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
NBL1 YHR199C-A Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
YPR096C YPR096C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Lethality
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex physical 1 1 1 PCA
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex genetic 1 1 1 Negative Genetic
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Positive Genetic
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 1 1 1 Negative Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Negative Genetic
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
COX4 YGL187C Subunit IV of cytochrome c oxidase genetic 1 1 1 Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex physical 1 1 1 Affinity Capture-Western
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
GCN2 YDR283C Protein kinase genetic 1 1 1 Negative Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Negative Genetic
GTR2 YGR163W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Positive Genetic
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
HAT2 YEL056W Subunit of the Hat1p-Hat2p histone acetyltransferase complex genetic 1 1 1 Negative Genetic
BDF2 YDL070W Protein involved in transcription initiation genetic 1 1 1 Negative Genetic
AEP1 YMR064W Protein required for expression of the mitochondrial OLI1 gene genetic 1 1 1 Negative Genetic
HHF2 YNL030W Histone H4 genetic 1 1 1 Negative Genetic
HIF1 YLL022C Non-essential component of the HAT-B histone acetyltransferase complex genetic 1 1 1 Negative Genetic
DPB4 YDR121W Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex genetic 1 1 1 Negative Genetic
IML3 YBR107C Outer kinetochore protein and component of the Ctf19 complex genetic 1 1 1 Negative Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Positive Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Positive Genetic
DIB1 YPR082C 17-kDa component of the U4/U6aU5 tri-snRNP physical 1 1 1 Affinity Capture-MS
LSM4 YER112W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Positive Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
DUR12 YBR208C Urea amidolyase genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Negative Genetic
HTA1 YDR225W Histone H2A genetic 1 1 1 Positive Genetic
FYV8 YGR196C Protein of unknown function genetic 1 1 1 Negative Genetic
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 1 1 1 Negative Genetic
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 1 1 1 Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Negative Genetic
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 1 1 1 Positive Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Positive Genetic
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Negative Genetic
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Negative Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
HTB1 YDR224C Histone H2B genetic 1 1 1 Positive Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase physical 1 1 1 Affinity Capture-RNA
ECM10 YEL030W Heat shock protein of the Hsp70 family genetic 1 1 1 Negative Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Negative Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Positive Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Positive Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Positive Genetic
LRO1 YNR008W Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) genetic 1 1 1 Negative Genetic
ADD66 YKL206C Protein involved in 20S proteasome assembly genetic 1 1 1 Negative Genetic
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Negative Genetic
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome physical 1 1 1 Affinity Capture-MS
EMI2 YDR516C Hexokinase expressed during growth with low glucose levels genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Positive Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Positive Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Positive Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Negative Genetic
GSY1 YFR015C Glycogen synthase genetic 1 1 1 Negative Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 1 1 1 Negative Genetic
LOS1 YKL205W Nuclear pore protein genetic 1 1 1 Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Synthetic Lethality
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Negative Genetic
CKI1 YLR133W Choline kinase genetic 1 1 1 Negative Genetic
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 1 1 1 Negative Genetic
IGO1 YNL157W Protein required for initiation of G0 program genetic 1 1 1 Phenotypic Suppression
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
CRC1 YOR100C Mitochondrial inner membrane carnitine transporter genetic 1 1 1 Negative Genetic
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Positive Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
ATP7 YKL016C Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Positive Genetic
FZF1 YGL254W Transcription factor involved in sulfite metabolism genetic 1 1 1 Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 1 1 1 Positive Genetic
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Positive Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
LPP1 YDR503C Lipid phosphate phosphatase genetic 1 1 1 Negative Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Negative Genetic
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
CSM3 YMR048W Replication fork associated factor genetic 1 1 1 Positive Genetic
COQ5 YML110C 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase genetic 1 1 1 Negative Genetic
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 1 1 1 Negative Genetic
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
DOC1 YGL240W Processivity factor genetic 1 1 1 Negative Genetic
BMT5 YIL096C Methyltransferase required for m3U2634 methylation of the 25S rRNA genetic 1 1 1 Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Positive Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 1 1 1 Positive Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Positive Genetic
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
CLC1 YGR167W Clathrin light chain genetic 1 1 1 Positive Genetic
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Positive Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
BIK1 YCL029C Microtubule-associated protein genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
DPH2 YKL191W Protein required for synthesis of diphthamide genetic 1 1 1 Negative Genetic
KTI11 YBL071W-A Zn-ribbon protein that co-purifies with Dph1 and Dph2 genetic 1 1 1 Negative Genetic
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes genetic 1 1 1 Negative Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Negative Genetic
GAL80 YML051W Transcriptional regulator involved in the repression of GAL genes genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
EMC5 YIL027C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
BUD6 YLR319C Actin- and formin-interacting protein genetic 1 1 1 Negative Genetic
GNT1 YOR320C N-acetylglucosaminyltransferase physical 1 1 1 Two-hybrid
GNT1 YOR320C N-acetylglucosaminyltransferase genetic 1 1 1 Negative Genetic
HFM1 YGL251C Meiosis specific DNA helicase physical 1 1 1 Two-hybrid
FMP42 YMR221C Putative protein of unknown function physical 1 1 1 Two-hybrid
AZF1 YOR113W Zinc-finger transcription factor genetic 1 1 1 Negative Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ADY4 YLR227C Structural component of the meiotic outer plaque genetic 1 1 1 Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Synthetic Lethality
HHT2 YNL031C Histone H3 genetic 1 1 1 Negative Genetic
EIS1 YMR031C Component of the eisosome required for proper eisosome assembly genetic 1 1 1 Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 1 1 1 Dosage Rescue
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
ABZ1 YNR033W Para-aminobenzoate (PABA) synthase genetic 1 1 1 Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Positive Genetic
FUR1 YHR128W Uracil phosphoribosyltransferase genetic 1 1 1 Negative Genetic
FRK1 YPL141C Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
BCH2 YKR027W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Negative Genetic
CST26 YBR042C Acyltransferase genetic 1 1 1 Negative Genetic
GAT2 YMR136W Protein containing GATA family zinc finger motifs genetic 1 1 1 Negative Genetic
ERV15 YBR210W Protein involved in export of proteins from the endoplasmic reticulum genetic 1 1 1 Negative Genetic
ATP14 YLR295C Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Negative Genetic
COQ11 YLR290C Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes genetic 1 1 1 Negative Genetic
CAB4 YGR277C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Positive Genetic
BIO2 YGR286C Biotin synthase genetic 1 1 1 Negative Genetic
ALD6 YPL061W Cytosolic aldehyde dehydrogenase genetic 1 1 1 Positive Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Negative Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
IZH3 YLR023C Membrane protein involved in zinc ion homeostasis genetic 1 1 1 Negative Genetic
CGI121 YML036W Component of the EKC/KEOPS complex genetic 1 1 1 Positive Genetic
KIN4 YOR233W Serine/threonine protein kinase genetic 1 1 1 Positive Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
COA3 YJL062W-A Mitochondrial protein required for cytochrome c oxidase assembly genetic 1 1 1 Negative Genetic
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
GVP36 YIL041W BAR domain protein that localizes to early and late Golgi vesicles genetic 1 1 1 Negative Genetic
DGR2 YKL121W Protein of unknown function genetic 1 1 1 Positive Genetic
CHS7 YHR142W Protein of unknown function genetic 1 1 1 Negative Genetic
DAP2 YHR028C Dipeptidyl aminopeptidase genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
AAD4 YDL243C Putative aryl-alcohol dehydrogenase genetic 1 1 1 Negative Genetic
DOT5 YIL010W Nuclear thiol peroxidase genetic 1 1 1 Negative Genetic
JJJ3 YJR097W Iron-binding protein genetic 1 1 1 Negative Genetic
HXT2 YMR011W High-affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Positive Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Positive Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 1 1 1 Negative Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Positive Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 1 1 1 Negative Genetic
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 1 1 1 Negative Genetic
DUS4 YLR405W Dihydrouridine synthase genetic 1 1 1 Negative Genetic
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly genetic 1 1 1 Negative Genetic
EDS1 YBR033W Putative zinc cluster protein, predicted to be a transcription factor genetic 1 1 1 Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
BSC4 YNL269W Protein of unknown function genetic 1 1 1 Positive Genetic
AIM14 YGL160W NADPH oxidase localized to the perinuclear ER genetic 1 1 1 Negative Genetic
LCB4 YOR171C Sphingoid long-chain base kinase genetic 1 1 1 Negative Genetic
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Negative Genetic
IGO2 YHR132W-A Protein required for initiation of G0 program genetic 1 1 1 Phenotypic Suppression
ARR1 YPR199C Transcriptional activator of the basic leucine zipper (bZIP) family genetic 1 1 1 Negative Genetic
GLD1 YPR109W Component of Dsc E3 ligase complex in Golgi and endosomes genetic 1 1 1 Negative Genetic
LMO1 YLL007C Homolog of mammalian ELMO (Engulfment and celL MOtility) genetic 1 1 1 Positive Genetic
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Negative Genetic
CPR8 YNR028W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Negative Genetic
GAT3 YLR013W Protein containing GATA family zinc finger motifs genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
AIM36 YMR157C Protein of unknown function genetic 1 1 1 Negative Genetic
HST2 YPL015C Cytoplasmic NAD(+)-dependent protein deacetylase genetic 1 1 1 Negative Genetic
LEU5 YHR002W Mitochondrial carrier protein genetic 1 1 1 Negative Genetic
LDB16 YCL005W Protein involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
ADF1 YCL058W-A Transcriptional repressor encoded by the FYV5 antisense strand genetic 1 1 1 Positive Genetic
FYV12 YOR183W Protein of unknown function genetic 1 1 1 Negative Genetic