| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
physical |
19 |
5 |
12 |
Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-fractionation, Reconstituted Complex, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western |
| PDS1 |
YDR113C |
Securin |
physical |
15 |
4 |
13 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity |
| MAD3 |
YJL013C |
Subunit of spindle-assembly checkpoint complex |
physical |
12 |
5 |
8 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-Western |
| PDS1 |
YDR113C |
Securin |
genetic |
9 |
5 |
8 |
Dosage Rescue, Synthetic Lethality, Synthetic Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Lethality, Synthetic Rescue, Synthetic Rescue, Positive Genetic |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
physical |
7 |
3 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid |
| SWM1 |
YDR260C |
Subunit of the anaphase-promoting complex (APC) |
genetic |
7 |
3 |
4 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
6 |
3 |
6 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments |
| APC9 |
YLR102C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
6 |
3 |
4 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
6 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
6 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
6 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
5 |
4 |
5 |
Dosage Lethality, Synthetic Lethality, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
5 |
4 |
4 |
Synthetic Lethality, Synthetic Rescue, Negative Genetic, Negative Genetic, Dosage Lethality |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
physical |
5 |
3 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Co-localization, Two-hybrid, Affinity Capture-Western |
| CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
5 |
3 |
4 |
Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Phenotypic Enhancement |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
5 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
5 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
5 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
5 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
5 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
5 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
5 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
5 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
5 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Affinity Capture-Western |
| CDC16 |
YKL022C |
Subunit of the anaphase-promoting complex/cyclosome (APC/C) |
physical |
4 |
2 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex |
| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
4 |
2 |
4 |
Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Synthetic Rescue, Negative Genetic, Negative Genetic |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CDC26 |
YFR036W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
4 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
| CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
4 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
4 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
4 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
4 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| ADA2 |
YDR448W |
Transcription coactivator |
genetic |
4 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
4 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality |
| EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
4 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
4 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
4 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
4 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
4 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
4 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
4 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
3 |
2 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence |
| CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
physical |
3 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity |
| MSN5 |
YDR335W |
Karyopherin |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
3 |
3 |
2 |
Dosage Rescue, Synthetic Lethality, Negative Genetic |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
3 |
3 |
2 |
Phenotypic Suppression, Phenotypic Enhancement, Negative Genetic |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Negative Genetic, Negative Genetic |
| BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
3 |
2 |
2 |
Dosage Rescue, Negative Genetic, Negative Genetic |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
3 |
2 |
2 |
Dosage Rescue, Synthetic Lethality, Synthetic Lethality |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| HNT1 |
YDL125C |
Adenosine 5'-monophosphoramidase |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
| VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| ZDS2 |
YML109W |
Protein with a role in regulating Swe1p-dependent polarized growth |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TMA64 |
YDR117C |
Protein of unknown function that associates with ribosomes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SPO12 |
YHR152W |
Nucleolar protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NUP100 |
YKL068W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DYN3 |
YMR299C |
Dynein light intermediate chain (LIC) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VIK1 |
YPL253C |
Protein that forms a kinesin-14 heterodimeric motor with Kar3p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
physical |
3 |
1 |
2 |
Two-hybrid, Two-hybrid, Two-hybrid |
| RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
3 |
3 |
1 |
Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Suppression |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
2 |
1 |
Positive Genetic, Negative Genetic, Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
3 |
2 |
1 |
Positive Genetic, Negative Genetic, Negative Genetic |
| CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
| CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Co-fractionation |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
| CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Biochemical Activity |
| CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
| MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
2 |
2 |
2 |
Dosage Rescue, Positive Genetic |
| VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Lethality |
| TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Positive Genetic |
| ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
| MIH1 |
YMR036C |
Protein tyrosine phosphatase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
| AMA1 |
YGR225W |
Activator of meiotic anaphase promoting complex (APC/C) |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Biochemical Activity |
| AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
| CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
| CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| KIP1 |
YBL063W |
Kinesin-related motor protein |
genetic |
2 |
1 |
2 |
Phenotypic Suppression, Phenotypic Suppression |
| MUM2 |
YBR057C |
Protein essential for meiotic DNA replication and sporulation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SDD2 |
YMR074C |
Protein with homology to human PDCD5 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FDO1 |
YMR144W |
Protein involved in directionality of mating type switching |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MBF1 |
YOR298C-A |
Transcriptional coactivator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RNY1 |
YPL123C |
Vacuolar RNase of the T(2) family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ZDS1 |
YMR273C |
Protein with a role in regulating Swe1p-dependent polarized growth |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
| BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| HEM1 |
YDR232W |
5-aminolevulinate synthase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| MRS6 |
YOR370C |
Rab escort protein |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| SGT1 |
YOR057W |
Cochaperone protein |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| APC2 |
YLR127C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| CDC16 |
YKL022C |
Subunit of the anaphase-promoting complex/cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| CGR1 |
YGL029W |
Protein involved in nucleolar integrity and processing of pre-rRNA |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| ECM29 |
YHL030W |
Scaffold protein |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| GPT2 |
YKR067W |
Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| KTI12 |
YKL110C |
Protein that plays a role in modification of tRNA wobble nucleosides |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| OAR1 |
YKL055C |
Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| PEP3 |
YLR148W |
Component of CORVET membrane tethering complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| PEP5 |
YMR231W |
Histone E3 ligase, component of CORVET membrane tethering complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| PSY2 |
YNL201C |
Subunit of protein phosphatase PP4 complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SAT4 |
YCR008W |
Ser/Thr protein kinase involved in salt tolerance, nutrient response |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SHC1 |
YER096W |
Sporulation-specific activator of Chs3p (chitin synthase III) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SWC3 |
YAL011W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| TRK1 |
YJL129C |
Component of the Trk1p-Trk2p potassium transport system |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| UBP14 |
YBR058C |
Ubiquitin-specific protease |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| VMA22 |
YHR060W |
Protein that is required for vacuolar H+-ATPase (V-ATPase) function |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| VMA5 |
YKL080W |
Subunit C of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| VPS33 |
YLR396C |
ATP-binding protein that is a subunit of the HOPS and CORVET complexes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS45 |
YGL095C |
Protein of the Sec1p/Munc-18 family |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| YSA1 |
YBR111C |
Nudix hydrolase family member with ADP-ribose pyrophosphatase activity |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| GPI17 |
YDR434W |
Transmembrane protein |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| NSE1 |
YLR007W |
Component of the SMC5-SMC6 complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MCM10 |
YIL150C |
Essential chromatin-associated protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RRN3 |
YKL125W |
Protein required for transcription of rDNA by RNA polymerase I |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| UTP15 |
YMR093W |
Nucleolar protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YTM1 |
YOR272W |
Ribosomal assembly factor and 66S pre-ribosomal particle constituent |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRI2 |
YKL045W |
Subunit of DNA primase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HRP1 |
YOL123W |
Subunit of cleavage factor I |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPS21A |
YKR057W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DPH5 |
YLR172C |
Methyltransferase required for synthesis of diphthamide |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| KAP120 |
YPL125W |
Karyopherin responsible for the nuclear import of Rpf1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SIS2 |
YKR072C |
Negative regulatory subunit of protein phosphatase 1 (Ppz1p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YML119W |
YML119W |
Putative protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SOK1 |
YDR006C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TIF1 |
YKR059W |
Translation initiation factor eIF4A |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YLL032C |
YLL032C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SWM2 |
YNR004W |
Protein with a role in snRNA and snoRNA cap trimethylation |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TSR3 |
YOR006C |
Protein required for 20S pre-rRNA processing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PET20 |
YPL159C |
Mitochondrial protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| ACF2 |
YLR144C |
Intracellular beta-1,3-endoglucanase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RSF2 |
YJR127C |
Zinc-finger protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| NDD1 |
YOR372C |
Transcriptional activator essential for nuclear division |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRX1 |
YOL077C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AXL2 |
YIL140W |
Integral plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AOS1 |
YPR180W |
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATP11 |
YNL315C |
Molecular chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAP1 |
YHR047C |
Arginine/alanine amino peptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATP2 |
YJR121W |
Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACH1 |
YBL015W |
Protein with CoA transferase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AXL1 |
YPR122W |
Haploid specific endoprotease of a-factor mating pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAD3 |
YJL013C |
Subunit of spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MKK2 |
YPL140C |
MAPKK involved in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MDH1 |
YKL085W |
Mitochondrial malate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC26 |
YFR036W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
physical |
1 |
1 |
1 |
Two-hybrid |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
physical |
1 |
1 |
1 |
Co-localization |
| REC8 |
YPR007C |
Meiosis-specific component of the sister chromatid cohesion complex |
physical |
1 |
1 |
1 |
Co-localization |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EFM6 |
YNL024C |
Putative S-adenosylmethionine-dependent lysine methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSP1 |
YPL004C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HEF3 |
YNL014W |
Translational elongation factor EF-3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PNC1 |
YGL037C |
Nicotinamidase that converts nicotinamide to nicotinic acid |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| SGO1 |
YOR073W |
Component of the spindle checkpoint |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SPO13 |
YHR014W |
Meiotic regulator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SAS3 |
YBL052C |
Histone acetyltransferase catalytic subunit of NuA3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HHF1 |
YBR009C |
Histone H4 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YDR061W |
YDR061W |
Protein with similarity to ABC transporter family members |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DNF2 |
YDR093W |
Aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRT13 |
YER066W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YMD8 |
YML038C |
Putative nucleotide sugar transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TTI2 |
YJR136C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IGO2 |
YHR132W-A |
Protein required for initiation of G0 program |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PRP45 |
YAL032C |
Protein required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDS1 |
YBR029C |
Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CIA1 |
YDR267C |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YCG1 |
YDR325W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RBA50 |
YDR527W |
Protein involved in transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FRS2 |
YFL022C |
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TUB2 |
YFL037W |
Beta-tubulin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GRS1 |
YBR121C |
Cytoplasmic and mitochondrial glycyl-tRNA synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBC9 |
YDL064W |
SUMO-conjugating enzyme involved in the Smt3p conjugation pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DOP1 |
YDR141C |
Protein involved in vesicular transport at trans-Golgi network (TGN) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SYF1 |
YDR416W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PHS1 |
YJL097W |
Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LIP1 |
YMR298W |
Ceramide synthase subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP8 |
YOL144W |
Nucleolar protein required for 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIM50 |
YPL063W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MAS2 |
YHR024C |
Alpha subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PTI1 |
YGR156W |
Essential component of CPF (cleavage and polyadenylation factor) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MTR3 |
YGR158C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI14 |
YJR013W |
Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SFH1 |
YLR321C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RNA14 |
YMR061W |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HAS1 |
YMR290C |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSU72 |
YNL222W |
Phosphatase and transcription/RNA-processing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SYC1 |
YOR179C |
Subunit of the APT subcomplex of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RXT3 |
YDL076C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNG1 |
YGR197C |
Protein involved in resistance to nitrosoguanidine and 6-azauracil |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPT52 |
YKR014C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EMA19 |
YLR050C |
Integral ER membrane protein involved in protein sorting |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAX2 |
YLR084C |
Protein required for the maintenance of bud site selection |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMT1 |
YJL147C |
Translational repressor of the mitochondrial ATP6/8 mRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MDM1 |
YML104C |
PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FMT1 |
YBL013W |
Methionyl-tRNA formyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YBR085C-A |
YBR085C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FES1 |
YBR101C |
Hsp70 (Ssa1p) nucleotide exchange factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COX18 |
YGR062C |
Protein required for membrane insertion of C-terminus of Cox2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YLR156C-A |
YLR156C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MTG1 |
YMR097C |
Putative GTPase peripheral to the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCV2 |
YMR189W |
P subunit of the mitochondrial glycine decarboxylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOR7 |
YMR251W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NST1 |
YNL091W |
Translational inhibitor and suppressor of proteasome-assembly defects |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL11A |
YPR102C |
Ribosomal 60S subunit protein L11A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CHS2 |
YBR038W |
Chitin synthase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC3 |
YBR058C-A |
Protein that stimulates the activity of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC5 |
YBR087W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFC1 |
YBR123C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP10 |
YDL031W |
Putative ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEM13 |
YDR044W |
Coproporphyrinogen III oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPI1 |
YDR050C |
Triose phosphate isomerase, abundant glycolytic enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC1 |
YDR177W |
Ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP42 |
YDR235W |
U1 snRNP protein involved in splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP28 |
YDR243C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRB7 |
YDR308C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP7 |
YER082C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT15 |
YER148W |
TATA-binding protein (TBP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB1 |
YIL106W |
Component of the mitotic exit network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP159 |
YIL115C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MVD1 |
YNR043W |
Mevalonate pyrophosphate decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC97 |
YHR172W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP6 |
YDR449C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP4 |
YHR069C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC2 |
YJR068W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPP1 |
YGR198W |
Cargo-transport protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP2 |
YGR253C |
Alpha 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP1 |
YHR062C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CFD1 |
YIL003W |
Highly conserved iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRR1 |
YIL026C |
Subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP25 |
YIL091C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN7 |
YJL025W |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM54 |
YJL054W |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTR2 |
YKL186C |
mRNA transport regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBA1 |
YKL210W |
Ubiquitin activating enzyme (E1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOF1 |
YLL011W |
Protein required for biogenesis of 40S (small) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FCF2 |
YLR051C |
Nucleolar protein involved in the early steps of 35S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC45 |
YLR103C |
DNA replication initiation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSL5 |
YLR116W |
Component of commitment complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP13 |
YLR222C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP21 |
YLR409C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP39 |
YML046W |
U1 snRNP protein involved in splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRB1 |
YMR131C |
Specific assembly chaperone for ribosomal protein Rpl3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN9 |
YMR270C |
Protein involved in promoting high level transcription of rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP1 |
YNL189W |
Karyopherin alpha homolog |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIO2 |
YNL207W |
Essential serine kinase involved in the processing of 20S pre-rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESF2 |
YNR054C |
Essential nucleolar protein involved in pre-18S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RKI1 |
YOR095C |
Ribose-5-phosphate ketol-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIO1 |
YOR119C |
Serine kinase involved in cell cycle regulation and rDNA integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SME1 |
YOR159C |
Core Sm protein Sm E |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PLP2 |
YOR281C |
Protein that interacts with the CCT complex to stimulate actin folding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOG2 |
YOR353C |
Key component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEN54 |
YPL083C |
Subunit of the tRNA splicing endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC29 |
YPL124W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NGR1 |
YBR212W |
RNA binding protein that negatively regulates growth rate |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCR090C |
YCR090C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPT1 |
YDR072C |
Inositolphosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PLP1 |
YDR183W |
Protein that interacts with CCT (chaperonin containing TCP-1) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS26B |
YER131W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR127W |
YGR127W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HGH1 |
YGR187C |
Chaperone protein for translation factor eEF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS7 |
YHR142W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPH1 |
YIL103W |
Protein required for synthesis of diphthamide |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMP21 |
YIL154C |
Transcriptional activator involved in maintenance of ion homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAT4 |
YIR013C |
Protein containing GATA family zinc finger motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPS1 |
YJL172W |
Vacuolar carboxypeptidase S |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL43B |
YJR094W-A |
Ribosomal 60S subunit protein L43B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKL075C |
YKL075C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRR1 |
YKL116C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMC1 |
YKL137W |
Copper-binding protein of the mitochondrial intermembrane space |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRA2 |
YKL214C |
Member of the REF (RNA and export factor binding proteins) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRT3 |
YLR097C |
Putative SCF-ubiquitin ligase F-box protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPE4 |
YLR146C |
Spermine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNH203 |
YLR154C |
Ribonuclease H2 subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBA1 |
YLR199C |
Protein involved in 20S proteasome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TDA5 |
YLR426W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD10 |
YML095C |
Single-stranded DNA endonuclease (with Rad1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR253C |
YMR253C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRB1 |
YNL004W |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKT1 |
YNL085W |
Protein similar to nucleases that forms a complex with Pbp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAS5 |
YOL030W |
1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGA1 |
YOR127W |
GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SER1 |
YOR184W |
3-phosphoserine aminotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFM1 |
YOR279C |
Component of the Sum1p-Rfm1p-Hst1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAX1 |
YOR301W |
Protein involved in establishing bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIP2 |
YPL155C |
Kinesin-related motor protein involved in mitotic spindle positioning |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPE3 |
YPR069C |
Spermidine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKI3 |
YPR189W |
Ski complex component and TPR protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO2 |
YDL106C |
Homeobox transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP1 |
YDL122W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFA1 |
YDL168W |
Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD57 |
YDR004W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBX5 |
YDR330W |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GNP1 |
YDR508C |
Broad specificity amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR541C |
YDR541C |
Aldehyde reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMD8 |
YFR048W |
Cytosolic protein required for sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRH1 |
YGR189C |
Chitin transglycosylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAL12 |
YGR292W |
Maltase (alpha-D-glucosidase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EFM1 |
YHL039W |
Lysine methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INM1 |
YHR046C |
Inositol monophosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV10 |
YIL097W |
Subunit of GID complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REV7 |
YIL139C |
Accessory subunit of DNA polymerase zeta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPH1 |
YIR002C |
3'-5' DNA helicase involved in error-free bypass of DNA lesions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MND2 |
YIR025W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCK1 |
YKR097W |
Phosphoenolpyruvate carboxykinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPH6 |
YLR143W |
Diphthamide synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GID11 |
YLR149C |
Substrate receptor of the glucose-induced degradation-deficient (GID) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKI2 |
YLR398C |
Ski complex component and putative RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL44 |
YMR225C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NRM1 |
YNR009W |
Transcriptional co-repressor of MBF-regulated gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HST1 |
YOL068C |
NAD(+)-dependent histone deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RBL2 |
YOR265W |
Protein involved in microtubule morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRN1 |
YPL184C |
RNA-binding protein that may be involved in translational regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYT1 |
YPR095C |
Guanine nucleotide exchange factor (GEF) for Arf proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAY24 |
YPR153W |
Peripheral ER membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBS1 |
YBR165W |
Ubiquitin-conjugating enzyme suppressor that regulates Cdc34p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIG2 |
YCR089W |
Cell wall adhesin, expressed specifically during mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR045W |
YHR045W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOM71 |
YHR117W |
Mitochondrial outer membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIA6 |
YIL006W |
Mitochondrial NAD+ transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS6 |
YJL099W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GZF3 |
YJL110C |
GATA zinc finger protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL206C |
YJL206C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKG3 |
YLR187W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NMA1 |
YLR328W |
Nicotinic acid mononucleotide adenylyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OGG1 |
YML060W |
Nuclear and mitochondrial glycosylase/lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DSC2 |
YOL073C |
Multi-transmembrane subunit of the DSC ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HPF1 |
YOL155C |
Haze-protective mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NRT1 |
YOR071C |
High-affinity nicotinamide riboside transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP2 |
YOR124C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPR2 |
YOR214C |
Putative spore wall protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL264C |
YPL264C |
Endoplasmic reticulum protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR089W |
YPR089W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO7 |
YAL009W |
Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAL063C-A |
YAL063C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MST28 |
YAR033W |
Putative integral membrane protein, involved in vesicle formation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO11 |
YAR071W |
One of three repressible acid phosphatases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSY4 |
YBL046W |
Regulatory subunit of protein phosphatase PP4 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET112 |
YBL080C |
Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBL086C |
YBL086C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS3 |
YBR023C |
Chitin synthase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR071W |
YBR071W |
Protein of unknown function found in the cytoplasm and bud neck |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NHP6B |
YBR089C-A |
High-mobility group (HMG) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMY2 |
YBR172C |
GYF domain protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR184W |
YBR184W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBP1 |
YBR216C |
Protein involved in cellular response to oxidative stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR221W-A |
YBR221W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR238C |
YBR238C |
Mitochondrial membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIC12 |
YBR262C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCL001W-A |
YCL001W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMC1 |
YCL045C |
Member of conserved endoplasmic reticulum membrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POF1 |
YCL047C |
Nicotinamide mononucleotide-specific adenylyltransferase (NMNAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCR023C |
YCR023C |
Vacuolar membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCR024C-B |
YCR024C-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLM5 |
YCR024C |
Mitochondrial asparaginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HMRA1 |
YCR097W |
Silenced copy of a1 at HMR |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL057W |
YDL057W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYO1 |
YDL063C |
Transport adaptor or symportin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGT2 |
YDL138W |
Plasma membrane high glucose sensor that regulates glucose transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF3 |
YDL194W |
Plasma membrane low glucose sensor, regulates glucose transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP6 |
YDL213C |
rRNA-binding protein required for 40S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL218W |
YDL218W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD61 |
YDR014W |
Subunit of a complex that inhibits sister chromatid cohesion |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAS2 |
YDR020C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSH6 |
YDR097C |
Protein required for mismatch repair in mitosis and meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMT7 |
YDR307W |
Putative protein mannosyltransferase similar to Pmt1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL35 |
YDR322W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIZ1 |
YDR409W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL12B |
YDR418W |
Ribosomal 60S subunit protein L12B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL28 |
YDR462W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMI2 |
YDR516C |
Hexokinase expressed during growth with low glucose levels |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER076C |
YER076C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET6 |
YER091C |
Cobalamin-independent methionine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER189W |
YER189W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTC2 |
YFL004W |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UGA1 |
YGR019W |
Gamma-aminobutyrate (GABA) transaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORM1 |
YGR038W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPC1 |
YGR096W |
Mitochondrial membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THI4 |
YGR144W |
Thiazole synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR146C-A |
YGR146C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHL042W |
YHL042W |
Endoplasmic reticulum protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS24B |
YIL069C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIL089W |
YIL089W |
Protein of unknown function found in the ER and vacuole lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRT14 |
YIL127C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIL134C-A |
YIL134C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIT1 |
YIL164C |
Nitrilase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNX4 |
YJL036W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MHP1 |
YJL042W |
Microtubule-associated protein involved in microtubule organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IML2 |
YJL082W |
Protein required for clearance of inclusion bodies |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL136W-A |
YJL136W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDS2 |
YJL146W |
Protein involved in modulation of Ime2p activity during meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMA5 |
YJL216C |
Alpha-glucosidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET3 |
YJR010W |
ATP sulfurylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REC107 |
YJR021C |
Protein involved in early stages of meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| JJJ3 |
YJR097W |
Iron-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STR2 |
YJR130C |
Cystathionine gamma-synthase, converts cysteine into cystathionine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DEF1 |
YKL054C |
RNAPII degradation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMA19 |
YKL056C |
Protein that associates with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL38 |
YKL170W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL20 |
YKR085C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISA1 |
YLL027W |
Protein required for maturation of mitochondrial [4Fe-4S] proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEU1 |
YLR017W |
Methylthioadenosine phosphorylase (MTAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POM34 |
YLR018C |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEF1 |
YLR069C |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIN2 |
YLR096W |
S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR154C-H |
YLR154C-H |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRT15 |
YLR162W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PNP1 |
YLR209C |
Purine nucleoside phosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSO55 |
YLR281C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTS1 |
YLR286C |
Endochitinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEC3 |
YLR288C |
DNA damage and meiotic pachytene checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS29A |
YLR388W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR412C-A |
YLR412C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CGI121 |
YML036W |
Component of the EKC/KEOPS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MFT1 |
YML062C |
Subunit of the THO complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISF1 |
YMR081C |
Serine-rich, hydrophilic protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAF1 |
YMR102C |
Sterol-binding beta-propeller protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POM152 |
YMR129W |
Glycoprotein subunit of transmembrane ring of nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP2 |
YMR163C |
Peroxisome-specific receptor important for peroxisome inheritance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR181C |
YMR181C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIN3 |
YMR182W-A |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPG5 |
YMR191W |
Protein required for proteasome assembly during quiescence |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR262W |
YMR262W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDP3 |
YNL009W |
Peroxisomal NADP-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFB2 |
YNL049C |
Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNH201 |
YNL072W |
Ribonuclease H2 catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEU4 |
YNL104C |
Alpha-isopropylmalate synthase (2-isopropylmalate synthase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DGR1 |
YNL130C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IBD2 |
YNL164C |
Component of the BUB2-dependent spindle checkpoint pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRG9 |
YNL213C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO91 |
YNR013C |
Low-affinity vacuolar phosphate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF12 |
YNR023W |
73 kDa subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPR8 |
YNR028W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAN2 |
YNR073C |
Mannitol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL159C-A |
YOL159C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET127 |
YOR017W |
Protein with a role in 5'-end processing of mitochondrial RNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCO10 |
YOR020W-A |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOD5 |
YOR274W |
Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR376W-A |
YOR376W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCR1 |
YPL006W |
Vacuolar membrane protein involved with Npc2p in sterol trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL068C |
YPL068C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EEB1 |
YPL095C |
Acyl-coenzymeA:ethanol O-acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL119C-A |
YPL119C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL150W |
YPL150W |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIN2 |
YPL241C |
GTPase-activating protein (GAP) for Cin4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEL3 |
YPL263C |
Cytoplasmic protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FEX2 |
YPL279C |
Protein involved in fluoride export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP32 |
YPL280W |
Possible chaperone and cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| HHT1 |
YBR010W |
Histone H3 |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBR1 |
YIL043C |
Cytochrome b reductase and NADH-dependent reductase for Dph3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALD5 |
YER073W |
Mitochondrial aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG13 |
YPR185W |
Regulatory subunit of the Atg1p signaling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG8 |
YBL078C |
Ub-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG2 |
YNL242W |
Peripheral membrane protein required for autophagic vesicle formation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BAT2 |
YJR148W |
Cytosolic branched-chain amino acid (BCAA) aminotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APN2 |
YBL019W |
Class II abasic (AP) endonuclease involved in repair of DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCS1 |
YDR375C |
Protein translocase and chaperone required for Complex III assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ACM1 |
YPL267W |
Pseudosubstrate inhibitor of the APC/C |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE16 |
YLR028C |
Enzyme of 'de novo' purine biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG38 |
YLR211C |
Homodimeric subunit of autophagy-specific PtdIns-3-kinase complex I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAB4 |
YGR277C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BIL1 |
YOR304C-A |
Protein that binds Bud6p and has a role in actin cable assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARO7 |
YPR060C |
Chorismate mutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIG1 |
YHR101C |
Integral membrane protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASP3-2 |
YLR157C |
Cell-wall L-asparaginase II involved in asparagine catabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG41 |
YPL250C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BSC4 |
YNL269W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AGC1 |
YPR021C |
Mitochondrial amino acid transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BER1 |
YLR412W |
Protein involved in microtubule-related processes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |