Standard name Systematic name Name description Description
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase
Visualize the interactome of BCK1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 177

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.900 0.941 0.93
ER 0.057 NaN NaN
Mito NaN NaN 0.06

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 112

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
BCK1 1 0 0 4 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 11 3 9 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 10 4 9 Synthetic Rescue, Dosage Rescue, Synthetic Lethality, Negative Genetic, Synthetic Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Rescue
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 10 3 8 Positive Genetic, Positive Genetic, Positive Genetic, Dosage Growth Defect, Synthetic Growth Defect, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 9 2 9 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CHS5 YLR330W Component of the exomer complex genetic 9 3 7 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CHS7 YHR142W Protein of unknown function genetic 9 3 7 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 9 3 7 Negative Genetic, Negative Genetic, Negative Genetic, Dosage Rescue, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 9 2 7 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 9 2 7 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Dosage Rescue, Dosage Rescue
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 9 1 7 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 8 1 7 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 8 2 6 Dosage Rescue, Dosage Rescue, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 8 2 6 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 8 1 6 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 8 1 6 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 8 2 5 Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BNI1 YNL271C Formin genetic 7 2 7 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 7 2 6 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ROT2 YBR229C Glucosidase II catalytic subunit genetic 7 2 6 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 7 1 6 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway physical 7 5 5 Affinity Capture-MS, PCA, PCA, Reconstituted Complex, Protein-peptide, Protein-peptide, Affinity Capture-Western
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth genetic 7 3 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 7 2 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CWH41 YGL027C Processing alpha glucosidase I genetic 7 2 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 6 3 6 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase physical 6 3 5 Affinity Capture-MS, Biochemical Activity, Affinity Capture-MS, PCA, PCA, PCA
SPA2 YLL021W Component of the polarisome genetic 6 2 5 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SSD1 YDR293C Translational repressor genetic 6 2 5 Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VAC14 YLR386W Enzyme regulator genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 6 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 6 2 4 Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CNE1 YAL058W Calnexin genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 6 2 3 Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 5 2 5 Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 5 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway genetic 5 3 4 Dosage Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 5 2 4 Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 5 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 5 2 4 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 5 2 4 Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 5 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SMY1 YKL079W Kinesin-like myosin passenger-protein genetic 5 2 4 Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CWH43 YCR017C GPI lipid remodelase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YPS7 YDR349C Putative GPI-anchored aspartic protease genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PGM1 YKL127W Phosphoglucomutase, minor isoform genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OST6 YML019W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
KRE5 YOR336W Protein required for beta-1,6 glucan biosynthesis genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 5 4 3 Positive Genetic, Phenotypic Suppression, Dosage Rescue, Synthetic Rescue, Dosage Rescue
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 5 3 3 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 5 2 3 Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 5 2 3 Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PIR1 YKL164C O-glycosylated protein required for cell wall stability genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CHS3 YBR023C Chitin synthase III genetic 4 3 4 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic
CNB1 YKL190W Calcineurin B genetic 4 3 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Dosage Rescue
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 4 4 3 Synthetic Rescue, Synthetic Lethality, Dosage Growth Defect, Negative Genetic
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 4 3 3 Dosage Rescue, Synthetic Lethality, Negative Genetic, Negative Genetic
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 4 2 3 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 4 2 3 Negative Genetic, Negative Genetic, Negative Genetic, Dosage Rescue
ALG8 YOR067C Glucosyl transferase genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERV46 YAL042W Protein localized to COPII-coated vesicles genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ECM8 YBR076W Non-essential protein of unknown function genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CMD1 YBR109C Calmodulin genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERS1 YCR075C Protein involved in cystine transport genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BIO2 YGR286C Biotin synthase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PAL1 YDR348C Protein of unknown function thought to be involved in endocytosis genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PEF1 YGR058W Penta-EF-hand protein genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BUD6 YLR319C Actin- and formin-interacting protein genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NAB6 YML117W Putative RNA-binding protein genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC13 YLR208W Structural component of 3 complexes genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERG10 YPL028W Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway physical 3 3 3 Two-hybrid, Affinity Capture-MS, PCA
CHS1 YNL192W Chitin synthase I genetic 3 3 3 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
MKK2 YPL140C MAPKK involved in the protein kinase C signaling pathway physical 3 2 3 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS
MYO3 YKL129C One of two type I myosins physical 3 2 3 Two-hybrid, Two-hybrid, Affinity Capture-MS
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 3 2 3 Synthetic Lethality, Synthetic Lethality, Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 3 2 3 Dosage Rescue, Negative Genetic, Dosage Rescue
PHO80 YOL001W Cyclin genetic 3 2 3 Negative Genetic, Dosage Growth Defect, Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase genetic 3 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PXP1 YEL020C Peroxisomal matrix protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PER1 YCR044C Protein of the endoplasmic reticulum genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YIR042C YIR042C Putative protein of unknown function genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PEP12 YOR036W Target membrane receptor (t-SNARE) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ERI1 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
EMC6 YLL014W Member of conserved ER transmembrane complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
STE11 YLR362W Signal transducing MEK kinase genetic 3 3 2 Synthetic Rescue, Phenotypic Suppression, Phenotypic Enhancement
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) physical 3 2 2 Affinity Capture-MS, PCA, PCA
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
PFY1 YOR122C Profilin genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 3 2 2 Positive Genetic, Negative Genetic, Positive Genetic
ALG13 YGL047W Catalytic component of UDP-GlcNAc transferase genetic 3 2 2 Dosage Growth Defect, Negative Genetic, Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
JNM1 YMR294W Component of the yeast dynactin complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
VPS5 YOR069W Nexin-1 homolog genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BIG1 YHR101C Integral membrane protein of the endoplasmic reticulum genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 2 2 2 Biochemical Activity, Reconstituted Complex
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein physical 2 2 2 Biochemical Activity, Affinity Capture-MS
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 2 2 2 Biochemical Activity, Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 2 2 2 Biochemical Activity, Affinity Capture-MS
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 2 2 Negative Genetic, Dosage Growth Defect
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 2 2 2 Biochemical Activity, Affinity Capture-MS
STT4 YLR305C Phosphatidylinositol-4-kinase genetic 2 2 2 Synthetic Lethality, Negative Genetic
KDX1 YKL161C Protein kinase genetic 2 2 2 Negative Genetic, Phenotypic Suppression
BEM1 YBR200W Protein containing SH3-domains genetic 2 2 2 Negative Genetic, Dosage Growth Defect
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 2 2 2 Synthetic Lethality, Negative Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 2 2 2 Synthetic Lethality, Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 2 2 2 Synthetic Rescue, Negative Genetic
SBE2 YDR351W Protein required for bud growth genetic 2 2 2 Synthetic Lethality, Dosage Growth Defect
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p genetic 2 2 2 Synthetic Lethality, Dosage Rescue
PCL2 YDL127W Cyclin, interacts with cyclin-dependent kinase Pho85p genetic 2 2 2 Synthetic Lethality, Dosage Rescue
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 2 2 2 Negative Genetic, Dosage Growth Defect
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 2 2 2 Synthetic Growth Defect, Dosage Growth Defect
PKH1 YDR490C Serine/threonine protein kinase genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
YPK1 YKL126W S/T protein kinase genetic 2 2 2 Dosage Rescue, Phenotypic Suppression
PRR1 YKL116C Serine/threonine protein kinase genetic 2 2 2 Positive Genetic, Negative Genetic
MSG5 YNL053W Dual-specificity protein phosphatase genetic 2 2 2 Positive Genetic, Dosage Rescue
SWI6 YLR182W Transcription cofactor genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
POG1 YIL122W DNA-binding transcriptional activator genetic 2 2 2 Phenotypic Suppression, Dosage Growth Defect
SCH9 YHR205W AGC family protein kinase genetic 2 2 2 Synthetic Rescue, Synthetic Growth Defect
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 2 2 2 Dosage Growth Defect, Negative Genetic
BNI5 YNL166C Linker protein responsible for recruitment of myosin to the bud neck genetic 2 2 2 Dosage Growth Defect, Negative Genetic
SSO1 YPL232W Plasma membrane t-SNARE genetic 2 2 2 Dosage Growth Defect, Negative Genetic
SEC59 YMR013C Dolichol kinase genetic 2 2 2 Negative Genetic, Positive Genetic
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 2 2 2 Negative Genetic, Positive Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 2 2 2 Positive Genetic, Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 2 2 2 Dosage Rescue, Negative Genetic
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
AIM26 YKL037W Protein of unknown function genetic 2 2 2 Synthetic Lethality, Negative Genetic
ARC40 YBR234C Subunit of the ARP2/3 complex genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
ASF1 YJL115W Nucleosome assembly factor genetic 2 1 2 Negative Genetic, Negative Genetic
MYO5 YMR109W One of two type I myosin motors physical 2 1 2 Two-hybrid, Two-hybrid
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 2 1 2 Negative Genetic, Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 2 1 2 Negative Genetic, Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
BEM1 YBR200W Protein containing SH3-domains physical 2 1 2 Protein-peptide, Protein-peptide
PTP2 YOR208W Phosphotyrosine-specific phosphatase genetic 2 1 2 Dosage Rescue, Dosage Rescue
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 2 1 2 Negative Genetic, Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 1 2 Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 2 1 2 Negative Genetic, Negative Genetic
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) genetic 2 1 2 Negative Genetic, Negative Genetic
SHR3 YDL212W Endoplasmic reticulum packaging chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
SSY1 YDR160W Component of the SPS plasma membrane amino acid sensor system genetic 2 1 2 Negative Genetic, Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 2 1 2 Negative Genetic, Negative Genetic
CAB1 YDR531W Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase genetic 2 1 2 Negative Genetic, Negative Genetic
PTR3 YFR029W Component of the SPS plasma membrane amino acid sensor system genetic 2 1 2 Negative Genetic, Negative Genetic
DYS1 YHR068W Deoxyhypusine synthase genetic 2 1 2 Negative Genetic, Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 2 1 2 Negative Genetic, Negative Genetic
PEA2 YER149C Coiled-coil 12S polarisome subunit genetic 2 1 2 Negative Genetic, Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 2 1 2 Negative Genetic, Negative Genetic
SGD1 YLR336C Essential nuclear protein genetic 2 1 2 Negative Genetic, Negative Genetic
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 2 1 2 Negative Genetic, Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 2 1 2 Negative Genetic, Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 2 1 2 Negative Genetic, Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 2 1 2 Negative Genetic, Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 2 1 2 Negative Genetic, Negative Genetic
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 2 1 2 Positive Genetic, Positive Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 2 1 2 Negative Genetic, Negative Genetic
LRE1 YCL051W Protein involved in control of cell wall structure and stress response genetic 2 1 2 Negative Genetic, Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 2 1 2 Negative Genetic, Negative Genetic
YPT7 YML001W Rab family GTPase genetic 2 1 2 Positive Genetic, Positive Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 2 1 2 Negative Genetic, Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 2 1 2 Positive Genetic, Positive Genetic
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 2 1 2 Negative Genetic, Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 2 1 2 Negative Genetic, Negative Genetic
LST7 YGR057C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 2 1 2 Negative Genetic, Negative Genetic
FIG4 YNL325C Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 2 1 2 Negative Genetic, Negative Genetic
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 2 1 2 Negative Genetic, Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 2 2 1 Phenotypic Enhancement, Synthetic Rescue
MVP1 YMR004W Protein required for sorting proteins to the vacuole genetic 2 2 1 Negative Genetic, Positive Genetic
MRL1 YPR079W Membrane protein genetic 2 2 1 Negative Genetic, Positive Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 2 2 1 Positive Genetic, Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 2 2 1 Synthetic Growth Defect, Phenotypic Suppression
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
RRS1 YOR294W Essential protein that binds ribosomal protein L11 genetic 2 1 1 Positive Genetic, Positive Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SOV1 YMR066W Mitochondrial protein of unknown function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 2 1 1 Negative Genetic, Negative Genetic
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 2 1 1 Negative Genetic, Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 2 1 1 Negative Genetic, Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 2 1 1 Negative Genetic, Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 2 1 1 Negative Genetic, Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 2 1 1 Negative Genetic, Negative Genetic
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 2 1 1 Negative Genetic, Negative Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex genetic 2 1 1 Negative Genetic, Negative Genetic
MIF2 YKL089W Centromeric CDEIII region binding protein genetic 2 1 1 Negative Genetic, Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 2 1 1 Negative Genetic, Negative Genetic
GAA1 YLR088W Subunit of the GPI:protein transamidase complex genetic 2 1 1 Negative Genetic, Negative Genetic
ERG27 YLR100W 3-keto sterol reductase genetic 2 1 1 Negative Genetic, Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 2 1 1 Negative Genetic, Negative Genetic
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 2 1 1 Negative Genetic, Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 2 1 1 Negative Genetic, Negative Genetic
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase genetic 2 1 1 Negative Genetic, Negative Genetic
SMP3 YOR149C Alpha 1,2-mannosyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 2 1 1 Negative Genetic, Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 2 1 1 Negative Genetic, Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 2 1 1 Negative Genetic, Negative Genetic
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 2 1 1 Negative Genetic, Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
ADH1 YOL086C Alcohol dehydrogenase genetic 1 1 1 Negative Genetic
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 Biochemical Activity
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
AEP1 YMR064W Protein required for expression of the mitochondrial OLI1 gene physical 1 1 1 Affinity Capture-MS
ACK1 YDL203C Protein that functions in the cell wall integrity pathway genetic 1 1 1 Negative Genetic
ADA2 YDR448W Transcription coactivator genetic 1 1 1 Negative Genetic
ATG18 YFR021W Phosphoinositide binding protein genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Positive Genetic
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Two-hybrid
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 1 1 1 Affinity Capture-MS
YSP2 YDR326C Sterol-binding protein physical 1 1 1 Affinity Capture-MS
YIP5 YGL161C Protein that interacts with Rab GTPases physical 1 1 1 Affinity Capture-MS
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
LSP1 YPL004C Eisosome core component physical 1 1 1 Affinity Capture-MS
YMR295C YMR295C Protein of unknown function that associates with ribosomes physical 1 1 1 Biochemical Activity
YMR295C YMR295C Protein of unknown function that associates with ribosomes genetic 1 1 1 Dosage Growth Defect
MPC54 YOR177C Component of the meiotic outer plaque physical 1 1 1 Biochemical Activity
VAS1 YGR094W Mitochondrial and cytoplasmic valyl-tRNA synthetase physical 1 1 1 Biochemical Activity
VAS1 YGR094W Mitochondrial and cytoplasmic valyl-tRNA synthetase genetic 1 1 1 Dosage Growth Defect
CRN1 YLR429W Coronin physical 1 1 1 Biochemical Activity
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization physical 1 1 1 Biochemical Activity
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization genetic 1 1 1 Phenotypic Suppression
PBP2 YBR233W RNA binding protein physical 1 1 1 Biochemical Activity
EUC1 YMR111C Sequence-specific DNA binding protein physical 1 1 1 Biochemical Activity
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Biochemical Activity
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation physical 1 1 1 Biochemical Activity
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Biochemical Activity
GIR2 YDR152W Highly-acidic RWD domain-containing cytoplasmic protein physical 1 1 1 Biochemical Activity
YPL191C YPL191C K48-specific deubiquitinating (DUB) enzyme physical 1 1 1 Biochemical Activity
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation physical 1 1 1 Biochemical Activity
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein physical 1 1 1 Biochemical Activity
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Biochemical Activity
YNL034W YNL034W Putative protein of unknown function physical 1 1 1 Biochemical Activity
FYV6 YNL133C Protein of unknown function physical 1 1 1 Biochemical Activity
BUD4 YJR092W Anillin-like protein involved in bud-site selection physical 1 1 1 Biochemical Activity
YBR225W YBR225W Putative protein of unknown function physical 1 1 1 Biochemical Activity
SRO7 YPR032W Effector of Rab GTPase Sec4p physical 1 1 1 Biochemical Activity
YDR170W-A YDR170W-A Retrotransposon TYA Gag gene physical 1 1 1 Biochemical Activity
CUZ1 YNL155W Protein with a role in the ubiquitin-proteasome pathway physical 1 1 1 Biochemical Activity
ELO1 YJL196C Elongase I, medium-chain acyl elongase physical 1 1 1 Biochemical Activity
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p physical 1 1 1 Biochemical Activity
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role physical 1 1 1 Biochemical Activity
MSB3 YNL293W Rab GTPase-activating protein physical 1 1 1 Biochemical Activity
MSB3 YNL293W Rab GTPase-activating protein genetic 1 1 1 Dosage Growth Defect
YMC1 YPR058W Secondary mitochondrial inner membrane glycine transporter physical 1 1 1 Biochemical Activity
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p physical 1 1 1 Biochemical Activity
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p physical 1 1 1 Biochemical Activity
YDR034C-C YDR034C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
RPB10 YOR210W RNA polymerase subunit ABC10-beta physical 1 1 1 Biochemical Activity
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 1 1 1 Biochemical Activity
RCM1 YNL022C rRNA m5C methyltransferase physical 1 1 1 Biochemical Activity
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid physical 1 1 1 Biochemical Activity
CCW22 YDR134C Cell wall protein physical 1 1 1 Biochemical Activity
YML083C YML083C Protein of unknown function physical 1 1 1 Biochemical Activity
OSH2 YDL019C Member of an oxysterol-binding protein family with seven members physical 1 1 1 Biochemical Activity
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase physical 1 1 1 Biochemical Activity
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Biochemical Activity
SLA1 YBL007C Cytoskeletal protein binding protein physical 1 1 1 Biochemical Activity
YMR155W YMR155W Putative protein of unknown function physical 1 1 1 Biochemical Activity
YML037C YML037C Putative protein of unknown function physical 1 1 1 Biochemical Activity
ESBP6 YNL125C Protein with similarity to monocarboxylate permeases physical 1 1 1 Biochemical Activity
DFM1 YDR411C Endoplasmic reticulum (ER) localized protein physical 1 1 1 Biochemical Activity
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 1 1 1 Biochemical Activity
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Biochemical Activity
YPR137C-A YPR137C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
DUS1 YML080W Dihydrouridine synthase physical 1 1 1 Biochemical Activity
RGS2 YOR107W Negative regulator of glucose-induced cAMP signaling physical 1 1 1 Biochemical Activity
BDF2 YDL070W Protein involved in transcription initiation physical 1 1 1 Biochemical Activity
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex physical 1 1 1 Biochemical Activity
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase physical 1 1 1 Biochemical Activity
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails physical 1 1 1 Biochemical Activity
YNL054W-A YNL054W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
RPA12 YJR063W RNA polymerase I subunit A12.2 physical 1 1 1 Biochemical Activity
YPL257W-A YPL257W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 1 1 1 Biochemical Activity
YAK1 YJL141C Serine-threonine protein kinase physical 1 1 1 Biochemical Activity
YAK1 YJL141C Serine-threonine protein kinase genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
CBP1 YJL209W Mitochondrial protein, regulator of COB mRNA stability and translation physical 1 1 1 Affinity Capture-MS
CBS1 YDL069C Mitochondrial translational activator of the COB mRNA physical 1 1 1 Affinity Capture-MS
CIC1 YHR052W Essential protein that interacts with proteasome components physical 1 1 1 Affinity Capture-MS
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I physical 1 1 1 Affinity Capture-MS
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly physical 1 1 1 Affinity Capture-MS
FAA2 YER015W Medium chain fatty acyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring physical 1 1 1 Affinity Capture-MS
GSY1 YFR015C Glycogen synthase physical 1 1 1 Affinity Capture-MS
HAS1 YMR290C ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 Affinity Capture-MS
KOG1 YHR186C Subunit of TORC1 physical 1 1 1 Affinity Capture-MS
MAK5 YBR142W Essential nucleolar protein physical 1 1 1 Affinity Capture-MS
MRM1 YOR201C Ribose methyltransferase physical 1 1 1 Affinity Capture-MS
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing physical 1 1 1 Affinity Capture-MS
NOP13 YNL175C Nucleolar protein found in preribosomal complexes physical 1 1 1 Affinity Capture-MS
NOP2 YNL061W rRNA m5C methyltransferase physical 1 1 1 Affinity Capture-MS
NOP4 YPL043W Nucleolar protein physical 1 1 1 Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
PAM1 YDR251W Essential protein of unknown function physical 1 1 1 Affinity Capture-MS
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs physical 1 1 1 Affinity Capture-MS
PET309 YLR067C Specific translational activator for the COX1 mRNA physical 1 1 1 Affinity Capture-MS
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling physical 1 1 1 Affinity Capture-MS
POX1 YGL205W Fatty-acyl coenzyme A oxidase physical 1 1 1 Affinity Capture-MS
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 1 1 1 Affinity Capture-MS
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing genetic 1 1 1 Positive Genetic
RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p physical 1 1 1 Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 1 1 1 Affinity Capture-MS
RRS1 YOR294W Essential protein that binds ribosomal protein L11 physical 1 1 1 Affinity Capture-MS
SLH1 YGR271W Subunit of ribosome-associated quality control trigger complex (RQT) physical 1 1 1 Affinity Capture-MS
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 1 1 1 Affinity Capture-MS
STT4 YLR305C Phosphatidylinositol-4-kinase physical 1 1 1 Affinity Capture-MS
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 1 1 1 Affinity Capture-MS
UTP20 YBL004W Component of the small-subunit (SSU) processome physical 1 1 1 Affinity Capture-MS
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Affinity Capture-MS
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) physical 1 1 1 Affinity Capture-MS
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
PKH3 YDR466W Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p physical 1 1 1 Affinity Capture-MS
KDX1 YKL161C Protein kinase physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 PCA
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Positive Genetic
SPA2 YLL021W Component of the polarisome physical 1 1 1 PCA
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 PCA
PIL1 YGR086C Eisosome core component physical 1 1 1 PCA
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism physical 1 1 1 Reconstituted Complex
SHQ1 YIL104C Chaperone protein physical 1 1 1 Reconstituted Complex
JJJ3 YJR097W Iron-binding protein physical 1 1 1 Reconstituted Complex
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator genetic 1 1 1 Dosage Growth Defect
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Co-localization
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Synthetic Growth Defect
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Affinity Capture-MS
GIS1 YDR096W Histone demethylase and transcription factor genetic 1 1 1 Negative Genetic
YUR1 YJL139C Mannosyltransferase involved in protein N-glycosylation genetic 1 1 1 Synthetic Lethality
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 1 1 1 Synthetic Lethality
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Lethality
NPL6 YMR091C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Lethality
CDC53 YDL132W Cullin genetic 1 1 1 Synthetic Lethality
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Synthetic Growth Defect
MID2 YLR332W O-glycosylated plasma membrane protein genetic 1 1 1 Dosage Rescue
KAR1 YNL188W Protein involved in karyogamy and spindle pole body duplication genetic 1 1 1 Dosage Rescue
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Phenotypic Suppression
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Synthetic Growth Defect
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Dosage Rescue
PTC6 YCR079W Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Positive Genetic
PTP3 YER075C Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Negative Genetic
THR1 YHR025W Homoserine kinase genetic 1 1 1 Positive Genetic
OPY1 YBR129C Protein of unknown function genetic 1 1 1 Negative Genetic
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Positive Genetic
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Negative Genetic
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Positive Genetic
YPD1 YDL235C Osmotic stress-responsive phosphorelay intermediate sensor protein genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
PLM2 YDR501W Putative transcription factor, contains Forkhead Associated domain genetic 1 1 1 Positive Genetic
CMK1 YFR014C Calmodulin-dependent protein kinase genetic 1 1 1 Positive Genetic
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 1 1 1 Negative Genetic
IKS1 YJL057C Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
ESC1 YMR219W Protein involved in telomeric silencing genetic 1 1 1 Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Positive Genetic
FAR1 YJL157C CDK inhibitor and nuclear anchor genetic 1 1 1 Negative Genetic
KIN4 YOR233W Serine/threonine protein kinase genetic 1 1 1 Positive Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Dosage Rescue
MTL1 YGR023W Putative plasma membrane sensor genetic 1 1 1 Dosage Rescue
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Synthetic Lethality
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Synthetic Growth Defect
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Synthetic Growth Defect
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Synthetic Growth Defect
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Synthetic Growth Defect
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 1 1 1 Synthetic Growth Defect
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
PKH2 YOL100W Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
YPK2 YMR104C AGC-type S/T protein kinase genetic 1 1 1 Dosage Rescue
SRO77 YBL106C Protein with roles in exocytosis and cation homeostasis genetic 1 1 1 Positive Genetic
YPT31 YER031C Rab family GTPase genetic 1 1 1 Negative Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Negative Genetic
PEX1 YKL197C AAA-peroxin genetic 1 1 1 Negative Genetic
PEX6 YNL329C AAA-peroxin genetic 1 1 1 Negative Genetic
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein genetic 1 1 1 Negative Genetic
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
TAT1 YBR069C Amino acid transporter for valine, leucine, isoleucine, and tyrosine genetic 1 1 1 Negative Genetic
CAP2 YIL034C Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 1 1 1 Negative Genetic
BNR1 YIL159W Formin genetic 1 1 1 Negative Genetic
CAP1 YKL007W Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
CCH1 YGR217W Voltage-gated high-affinity calcium channel genetic 1 1 1 Negative Genetic
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Positive Genetic
MAL13 YGR288W MAL-activator protein genetic 1 1 1 Positive Genetic
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family genetic 1 1 1 Positive Genetic
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator genetic 1 1 1 Positive Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Positive Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Positive Genetic
RIM11 YMR139W Protein kinase genetic 1 1 1 Positive Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Positive Genetic
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
PTC3 YBL056W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Positive Genetic
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Positive Genetic
STP2 YHR006W Transcription factor genetic 1 1 1 Positive Genetic
MIG3 YER028C Transcriptional regulator genetic 1 1 1 Positive Genetic
YAP7 YOL028C Transcriptional repressor of nitric oxide oxidase genetic 1 1 1 Positive Genetic
YMR1 YJR110W Phosphatidylinositol 3-phosphate (PI3P) phosphatase genetic 1 1 1 Positive Genetic
NRG1 YDR043C Transcriptional repressor genetic 1 1 1 Positive Genetic
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Positive Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
SPT23 YKL020C ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
RSF2 YJR127C Zinc-finger protein genetic 1 1 1 Negative Genetic
KIN2 YLR096W S/T protein kinase genetic 1 1 1 Negative Genetic
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Negative Genetic
DOT6 YER088C Protein involved in rRNA and ribosome biogenesis genetic 1 1 1 Negative Genetic
KIN1 YDR122W S/T protein kinase genetic 1 1 1 Negative Genetic
HRK1 YOR267C Protein kinase genetic 1 1 1 Negative Genetic
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Negative Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway genetic 1 1 1 Dosage Rescue
WSC3 YOL105C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway genetic 1 1 1 Dosage Rescue
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
CYS3 YAL012W Cystathionine gamma-lyase genetic 1 1 1 Dosage Growth Defect
NDC1 YML031W Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 1 1 1 Dosage Growth Defect
BFR2 YDR299W Component of the SSU and 90S preribosomes genetic 1 1 1 Dosage Growth Defect
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Dosage Growth Defect
PCL8 YPL219W Cyclin genetic 1 1 1 Dosage Growth Defect
PRY1 YJL079C Lipid binding protein genetic 1 1 1 Dosage Growth Defect
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex genetic 1 1 1 Dosage Growth Defect
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 1 1 1 Dosage Growth Defect
KNH1 YDL049C Protein with similarity to Kre9p genetic 1 1 1 Dosage Growth Defect
GRE3 YHR104W Aldose reductase genetic 1 1 1 Dosage Growth Defect
MSB1 YOR188W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
GPP2 YER062C DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis genetic 1 1 1 Positive Genetic
TIP1 YBR067C Major cell wall mannoprotein with possible lipase activity genetic 1 1 1 Positive Genetic
GAS2 YLR343W 1,3-beta-glucanosyltransferase genetic 1 1 1 Positive Genetic
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Dosage Growth Defect
YPT53 YNL093W Stress-induced Rab family GTPase genetic 1 1 1 Dosage Growth Defect
MST28 YAR033W Putative integral membrane protein, involved in vesicle formation genetic 1 1 1 Positive Genetic
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor genetic 1 1 1 Dosage Growth Defect
MNL2 YLR057W Putative mannosidase involved in ER-associated protein degradation genetic 1 1 1 Dosage Growth Defect
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Dosage Growth Defect
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 1 1 1 Dosage Growth Defect
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 1 1 1 Dosage Growth Defect
CSA1 YPR174C Protein of unknown function genetic 1 1 1 Dosage Growth Defect
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Dosage Growth Defect
DFG5 YMR238W Putative mannosidase genetic 1 1 1 Positive Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 1 1 1 Negative Genetic
SDD2 YMR074C Protein with homology to human PDCD5 genetic 1 1 1 Dosage Growth Defect
SPS22 YCL048W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Dosage Growth Defect
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Dosage Growth Defect
TOS7 YOL019W Protein involved in secretion and cell wall organization genetic 1 1 1 Dosage Growth Defect
CLB4 YLR210W B-type cyclin involved in cell cycle progression genetic 1 1 1 Dosage Growth Defect
BUD8 YLR353W Protein involved in bud-site selection genetic 1 1 1 Dosage Growth Defect
PXP2 YJR111C Peroxisomal matrix protein with naturally active promoter genetic 1 1 1 Dosage Growth Defect
THO1 YER063W Conserved nuclear RNA-binding protein genetic 1 1 1 Dosage Growth Defect
ZAP1 YJL056C Zinc-regulated transcription factor genetic 1 1 1 Dosage Growth Defect
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex genetic 1 1 1 Dosage Growth Defect
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Dosage Growth Defect
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 1 1 1 Negative Genetic
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane genetic 1 1 1 Negative Genetic
GPI1 YGR216C Membrane protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
ERP1 YAR002C-A Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
GDA1 YEL042W Guanosine diphosphatase located in the Golgi genetic 1 1 1 Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
UTH1 YKR042W Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
ERG25 YGR060W C-4 methyl sterol oxidase genetic 1 1 1 Negative Genetic
LPP1 YDR503C Lipid phosphate phosphatase genetic 1 1 1 Positive Genetic
YPS6 YIR039C Putative GPI-anchored aspartic protease genetic 1 1 1 Positive Genetic
WSC4 YHL028W Endoplasmic reticulum (ER) membrane protein genetic 1 1 1 Positive Genetic
PEX34 YCL056C Protein that regulates peroxisome populations genetic 1 1 1 Dosage Growth Defect
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p genetic 1 1 1 Dosage Growth Defect
CUS2 YNL286W Putative checkpoint factor in transcription genetic 1 1 1 Dosage Growth Defect
GSC2 YGR032W Catalytic subunit of 1,3-beta-glucan synthase genetic 1 1 1 Dosage Growth Defect
PHO5 YBR093C Repressible acid phosphatase genetic 1 1 1 Dosage Growth Defect
YKR075C YKR075C Protein of unknown function genetic 1 1 1 Dosage Growth Defect
PRM2 YIL037C Pheromone-regulated protein genetic 1 1 1 Dosage Growth Defect
YER085C YER085C Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
KEL2 YGR238C Protein that negatively regulates mitotic exit genetic 1 1 1 Dosage Growth Defect
TOS8 YGL096W Homeodomain-containing protein and putative transcription factor genetic 1 1 1 Dosage Growth Defect
SBE22 YHR103W Protein involved in bud growth genetic 1 1 1 Dosage Growth Defect
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes genetic 1 1 1 Dosage Growth Defect
FIT3 YOR383C Mannoprotein that is incorporated into the cell wall genetic 1 1 1 Dosage Growth Defect
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Dosage Growth Defect
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Dosage Growth Defect
SNF7 YLR025W One of four subunits of the ESCRT-III complex genetic 1 1 1 Dosage Growth Defect
SIM1 YIL123W Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) genetic 1 1 1 Dosage Growth Defect
YNL108C YNL108C Protein phosphatase genetic 1 1 1 Dosage Growth Defect
PFK27 YOL136C 6-phosphofructo-2-kinase genetic 1 1 1 Dosage Growth Defect
COQ1 YBR003W Hexaprenyl pyrophosphate synthetase genetic 1 1 1 Dosage Growth Defect
YAP1801 YHR161C Protein of the AP180 family, involved in clathrin cage assembly genetic 1 1 1 Dosage Growth Defect
LSB1 YGR136W Negative regulator of actin nucleation-promoting factor activity genetic 1 1 1 Dosage Growth Defect
YPR015C YPR015C Putative zinc finger transcription factor genetic 1 1 1 Dosage Growth Defect
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 1 1 1 Dosage Growth Defect
TPO2 YGR138C Polyamine transporter of the major facilitator superfamily genetic 1 1 1 Dosage Growth Defect
PHO92 YDR374C Posttranscriptional regulator of phosphate and glucose metabolism genetic 1 1 1 Dosage Growth Defect
IST1 YNL265C Protein with positive role in the multivesicular body sorting pathway genetic 1 1 1 Dosage Growth Defect
ECM22 YLR228C Sterol regulatory element binding protein genetic 1 1 1 Dosage Growth Defect
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Dosage Growth Defect
PEX3 YDR329C Peroxisomal membrane protein (PMP) genetic 1 1 1 Dosage Growth Defect
PCL6 YER059W Pho85p cyclin of the Pho80p subfamily genetic 1 1 1 Dosage Growth Defect
TOA2 YKL058W TFIIA small subunit genetic 1 1 1 Dosage Growth Defect
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Dosage Growth Defect
HXT17 YNR072W Putative transmembrane polyol transporter genetic 1 1 1 Dosage Growth Defect
PIG2 YIL045W Putative type-1 protein phosphatase targeting subunit genetic 1 1 1 Dosage Growth Defect
SRO9 YCL037C Cytoplasmic RNA-binding protein genetic 1 1 1 Dosage Growth Defect
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis genetic 1 1 1 Dosage Growth Defect
NIT3 YLR351C Nit protein genetic 1 1 1 Dosage Growth Defect
RRN6 YBL014C Component of the core factor (CF) rDNA transcription factor complex genetic 1 1 1 Dosage Growth Defect
SLX4 YLR135W Endonuclease involved in processing DNA genetic 1 1 1 Dosage Growth Defect
YND1 YER005W Apyrase with wide substrate specificity genetic 1 1 1 Dosage Growth Defect
MLC1 YGL106W Essential light chain for Myo1p genetic 1 1 1 Dosage Growth Defect
HIP1 YGR191W High-affinity histidine permease genetic 1 1 1 Dosage Growth Defect
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Synthetic Growth Defect
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Positive Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Positive Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Positive Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Positive Genetic
UFE1 YOR075W t-SNARE protein required for retrograde vesicular traffic genetic 1 1 1 Positive Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) genetic 1 1 1 Positive Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Positive Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Positive Genetic
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Positive Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Positive Genetic
GSP1 YLR293C Ran GTPase genetic 1 1 1 Positive Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Positive Genetic
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 1 1 1 Positive Genetic
SPO7 YAL009W Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Positive Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Positive Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Positive Genetic
CBS2 YDR197W Mitochondrial translational activator of the COB mRNA genetic 1 1 1 Positive Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Positive Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Positive Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Positive Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Positive Genetic
MTC2 YKL098W Protein of unknown function genetic 1 1 1 Positive Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Positive Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Positive Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Positive Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Negative Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Negative Genetic
PDI1 YCL043C Protein disulfide isomerase genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
NUS1 YDL193W Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 1 1 1 Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Negative Genetic
CAB4 YGR277C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Negative Genetic
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Negative Genetic
CFD1 YIL003W Highly conserved iron-sulfur cluster binding protein genetic 1 1 1 Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Negative Genetic
SPC42 YKL042W Central plaque component of spindle pole body (SPB) genetic 1 1 1 Negative Genetic
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase genetic 1 1 1 Negative Genetic
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 genetic 1 1 1 Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
ERG12 YMR208W Mevalonate kinase genetic 1 1 1 Negative Genetic
TRS130 YMR218C Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Negative Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Negative Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
ERD2 YBL040C HDEL receptor genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
STN1 YDR082W Telomere end-binding and capping protein genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
TIP20 YGL145W Peripheral membrane protein required for COPI vesicle fusion to the ER genetic 1 1 1 Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Negative Genetic
URA6 YKL024C Uridylate kinase genetic 1 1 1 Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
CDC123 YLR215C Assembly factor for the eIF2 translation initiation factor complex genetic 1 1 1 Negative Genetic
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
SEC62 YPL094C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
RBG1 YAL036C Member of the DRG family of GTP-binding proteins genetic 1 1 1 Negative Genetic
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 1 1 1 Negative Genetic
KTI11 YBL071W-A Zn-ribbon protein that co-purifies with Dph1 and Dph2 genetic 1 1 1 Negative Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
YSY6 YBR162W-A Protein of unknown function genetic 1 1 1 Negative Genetic
YBR196C-A YBR196C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RCF3 YBR255C-A Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
UBP1 YDL122W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
LDB17 YDL146W Protein involved in the regulation of endocytosis genetic 1 1 1 Negative Genetic
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) genetic 1 1 1 Negative Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Negative Genetic
REF2 YDR195W RNA-binding protein genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p genetic 1 1 1 Negative Genetic
SXM1 YDR395W Nuclear transport factor (karyopherin) genetic 1 1 1 Negative Genetic
YDR524C-B YDR524C-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
YDR524W-C YDR524W-C Putative protein of unknown function genetic 1 1 1 Negative Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Negative Genetic
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity genetic 1 1 1 Negative Genetic
BUD25 YER014C-A Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Negative Genetic
KXD1 YGL079W Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Negative Genetic
CAX4 YGR036C Dolichyl pyrophosphate (Dol-P-P) phosphatase genetic 1 1 1 Negative Genetic
YGR122W YGR122W Protein that may be involved in pH regulation genetic 1 1 1 Negative Genetic
PEX4 YGR133W Peroxisomal ubiquitin conjugating enzyme genetic 1 1 1 Negative Genetic
RBG2 YGR173W Protein with a role in translation genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
TED1 YIL039W GPI-glycan remodelase genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Negative Genetic
YIL102C YIL102C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Synthetic Growth Defect
MRP8 YKL142W Protein of unknown function genetic 1 1 1 Negative Genetic
SKG1 YKR100C Transmembrane protein with a role in cell wall polymer composition genetic 1 1 1 Negative Genetic
PDR8 YLR266C Transcription factor genetic 1 1 1 Negative Genetic
HRI1 YLR301W Protein of unknown function that interacts with Sec72p and Hrr25p genetic 1 1 1 Negative Genetic
GRX8 YLR364W Glutaredoxin that employs a dithiol mechanism of catalysis genetic 1 1 1 Negative Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 1 1 1 Negative Genetic
YML100W-A YML100W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Negative Genetic
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex genetic 1 1 1 Negative Genetic
EPO1 YMR124W Protein involved in septin-ER tethering genetic 1 1 1 Negative Genetic
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 1 1 1 Negative Genetic
DDR48 YMR173W DNA damage-responsive protein genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
CAF40 YNL288W Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Negative Genetic
SNF8 YPL002C Component of the ESCRT-II complex genetic 1 1 1 Negative Genetic
YPL113C YPL113C Glyoxylate reductase genetic 1 1 1 Negative Genetic
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 1 1 1 Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
YPR108W-A YPR108W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
PTC2 YER089C Type 2C protein phosphatase (PP2C) genetic 1 1 1 Dosage Rescue
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Dosage Rescue
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Dosage Rescue
OCA2 YNL056W Protein of unknown function genetic 1 1 1 Dosage Rescue
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Dosage Rescue
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase genetic 1 1 1 Dosage Rescue
SVP26 YHR181W ER exit adaptor for Golgi mannosyltransferases genetic 1 1 1 Negative Genetic
FYV8 YGR196C Protein of unknown function genetic 1 1 1 Negative Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Negative Genetic
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering genetic 1 1 1 Negative Genetic
USO1 YDL058W Essential protein involved in vesicle-mediated ER to Golgi transport genetic 1 1 1 Positive Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Positive Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Positive Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Positive Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 1 1 1 Positive Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Positive Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 1 1 1 Positive Genetic
SCD6 YPR129W Repressor of translation initiation genetic 1 1 1 Positive Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Positive Genetic
GRX3 YDR098C Glutathione-dependent oxidoreductase genetic 1 1 1 Dosage Rescue
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase genetic 1 1 1 Dosage Rescue
CDC43 YGL155W Beta subunit of geranylgeranyltransferase type I genetic 1 1 1 Negative Genetic
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 1 1 1 Positive Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Positive Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
PRP8 YHR165C Component of U4/U6-U5 snRNP complex genetic 1 1 1 Negative Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 1 1 1 Positive Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Positive Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator genetic 1 1 1 Synthetic Growth Defect
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
YTA6 YPL074W Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family genetic 1 1 1 Dosage Rescue
YPR096C YPR096C Protein of unknown function genetic 1 1 1 Dosage Rescue
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) genetic 1 1 1 Negative Genetic
ADK1 YDR226W Adenylate kinase, required for purine metabolism physical 1 1 1 Biochemical Activity
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 1 1 1 Negative Genetic
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV physical 1 1 1 Biochemical Activity
APL4 YPR029C Gamma-adaptin genetic 1 1 1 Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Synthetic Lethality
ARG81 YML099C Zinc finger transcription factor involved in arginine-responsive genes genetic 1 1 1 Negative Genetic
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation physical 1 1 1 Biochemical Activity
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
APC9 YLR102C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Dosage Growth Defect
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Positive Genetic
AMA1 YGR225W Activator of meiotic anaphase promoting complex (APC/C) genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Dosage Growth Defect
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
BCH2 YKR027W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Dosage Growth Defect
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy genetic 1 1 1 Dosage Growth Defect
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Biochemical Activity
ATG21 YPL100W Phosphoinositide binding protein genetic 1 1 1 Negative Genetic
ATG41 YPL250C Protein of unknown function genetic 1 1 1 Negative Genetic