Standard name Systematic name Name description Description
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase High affinity Ca2+/Mn2+ P-type ATPase; required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting, processing; D53A mutant (Mn2+ transporting) is rapamycin sensitive, Q783A mutant (Ca2+ transporting) is rapamycin resistant; Mn2+ transport into Golgi lumen required for rapamycin sensitivity; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease; human ATP2C1 can complement yeast null mutant
Visualize the interactome of PMR1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.073 0.176 0.055
ER 0.934 0.778 0.916
Cort. Patches NaN 0.065 NaN
Cell Periphery NaN NaN 0.061
Nuc Periphery NaN NaN 0.061

GFP localization & abundance

GFP localization GFP abundance
ER 6900

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PMR1 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_4238 (Calcium-transporting ATPase 2 (EC 3.6.3.8) (Golgi Ca(2+)-ATPase))

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RUD3 YOR216C Golgi matrix protein genetic 10 2 7 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 8 2 8 Phenotypic Enhancement, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 8 2 6 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 8 2 6 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 8 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 7 3 6 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 7 2 6 Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GDT1 YBR187W Calcium and manganese transporter with higher affinity for Ca2+ genetic 6 4 5 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Enhancement
PMC1 YGL006W Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions genetic 6 4 5 Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 6 3 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
KIN3 YAR018C Nonessential serine/threonine protein kinase genetic 6 3 4 Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 6 2 4 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER genetic 6 2 4 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 5 2 5 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 5 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 5 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 5 2 4 Positive Genetic, Positive Genetic, Positive Genetic, Negative Genetic, Positive Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BIG1 YHR101C Integral membrane protein of the endoplasmic reticulum genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 5 2 3 Negative Genetic, Negative Genetic, Positive Genetic, Positive Genetic, Positive Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 5 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 5 2 3 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 5 2 3 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 5 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase genetic 5 2 3 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 5 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ROT2 YBR229C Glucosidase II catalytic subunit genetic 5 2 3 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 5 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CWH41 YGL027C Processing alpha glucosidase I genetic 5 2 3 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CNL1 YDR357C Subunit of the BLOC-1 complex involved in endosomal maturation genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SNN1 YNL086W Subunit of the BLOC-1 complex involved in endosomal maturation genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CCC1 YLR220W Vacuolar Fe2+/Mn2+ transporter genetic 4 3 4 Dosage Rescue, Dosage Rescue, Synthetic Growth Defect, Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 4 3 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Lethality
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 4 2 4 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 4 3 3 Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 4 3 3 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Positive Genetic
ARV1 YLR242C Cortical ER protein genetic 4 3 3 Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 4 3 3 Dosage Lethality, Negative Genetic, Dosage Rescue, Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 4 2 3 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 4 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 4 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 4 2 3 Negative Genetic, Negative Genetic, Dosage Rescue, Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 4 2 3 Negative Genetic, Negative Genetic, Positive Genetic, Positive Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 4 2 3 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 4 2 3 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic
ATX2 YOR079C Golgi membrane protein involved in manganese homeostasis genetic 4 2 3 Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
PER1 YCR044C Protein of the endoplasmic reticulum genetic 4 2 3 Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CHL1 YPL008W Probable DNA helicase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YND1 YER005W Apyrase with wide substrate specificity genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS60 YDR486C Protein involved in late endosome to vacuole transport genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS68 YOL129W Vacuolar membrane protein of unknown function genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PSK2 YOL045W PAS-domain containing serine/threonine protein kinase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MVB12 YGR206W ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LCB3 YJL134W Long-chain base-1-phosphate phosphatase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 4 2 2 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 4 2 2 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
STE24 YJR117W Highly conserved zinc metalloprotease genetic 4 2 2 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
SPC2 YML055W Subunit of signal peptidase complex genetic 4 2 2 Positive Genetic, Positive Genetic, Phenotypic Suppression, Phenotypic Suppression
YUR1 YJL139C Mannosyltransferase involved in protein N-glycosylation genetic 4 2 2 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
ALG8 YOR067C Glucosyl transferase genetic 4 2 2 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
BLI1 YKL061W Subunit of the BLOC-1 complex involved in endosomal maturation genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GEF1 YJR040W Voltage-gated chloride channel genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 4 1 2 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DCR2 YLR361C Protein phosphatase genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SMF1 YOL122C Divalent metal ion transporter genetic 3 3 3 Synthetic Growth Defect, Negative Genetic, Dosage Rescue
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 3 3 3 Synthetic Growth Defect, Positive Genetic, Negative Genetic
CIN8 YEL061C Bipolar kinesin motor protein genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
SOD2 YHR008C Mitochondrial manganese superoxide dismutase genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
YPT7 YML001W Rab family GTPase genetic 3 2 3 Dosage Rescue, Negative Genetic, Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
GCN2 YDR283C Protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 3 1 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
ERG25 YGR060W C-4 methyl sterol oxidase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BLS1 YLR408C Subunit of the BLOC-1 complex involved in endosomal maturation genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
KRE5 YOR336W Protein required for beta-1,6 glucan biosynthesis genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BUD14 YAR014C Protein involved in bud-site selection genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 3 2 2 Positive Genetic, Positive Genetic, Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 3 2 2 Negative Genetic, Negative Genetic, Synthetic Lethality
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 3 2 2 Negative Genetic, Positive Genetic, Positive Genetic
SEC22 YLR268W R-SNARE protein genetic 3 2 2 Negative Genetic, Negative Genetic, Positive Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 3 2 2 Negative Genetic, Negative Genetic, Synthetic Growth Defect
YHR078W YHR078W High osmolarity-regulated gene of unknown function genetic 3 2 2 Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
VTC4 YJL012C Vacuolar membrane polyphosphate polymerase genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ARF1 YDL192W ADP-ribosylation factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BAS1 YKR099W Myb-related transcription factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
OCA2 YNL056W Protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NRG1 YDR043C Transcriptional repressor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CQD1 YPL109C UbiB family mitochondrial protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CRR1 YLR213C Putative glycoside hydrolase of the spore wall envelope genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GLO4 YOR040W Mitochondrial glyoxalase II genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SSD1 YDR293C Translational repressor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PMT4 YJR143C Protein O-mannosyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TED1 YIL039W GPI-glycan remodelase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
STV1 YMR054W Subunit a of the vacuolar-ATPase V0 domain genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
RAV2 YDR202C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
SVF1 YDR346C Protein with a potential role in cell survival pathways genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VTC1 YER072W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
RAX2 YLR084C Protein required for the maintenance of bud site selection genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PXA1 YPL147W Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TOS1 YBR162C Covalently-bound cell wall protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
KIN4 YOR233W Serine/threonine protein kinase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DIE2 YGR227W Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
EMA19 YLR050C Integral ER membrane protein involved in protein sorting genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MYG1 YER156C Protein involved in mitochondrial function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
EMC2 YJR088C Member of conserved ER transmembrane complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PET20 YPL159C Mitochondrial protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 3 3 1 Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Suppression
CDC42 YLR229C Small rho-like GTPase genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
ASF1 YJL115W Nucleosome assembly factor genetic 2 2 2 Synthetic Lethality, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 2 2 2 Dosage Rescue, Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 2 2 2 Negative Genetic, Positive Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 2 2 2 Dosage Lethality, Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 2 2 2 Synthetic Lethality, Negative Genetic
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 2 2 2 Dosage Lethality, Negative Genetic
SEC21 YNL287W Gamma subunit of coatomer genetic 2 2 2 Dosage Lethality, Negative Genetic
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RAD51 YER095W Strand exchange protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 2 2 2 Negative Genetic, Synthetic Rescue
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 2 2 2 Negative Genetic, Positive Genetic
SCH9 YHR205W AGC family protein kinase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex genetic 2 2 2 Dosage Rescue, Negative Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 2 2 2 Dosage Rescue, Negative Genetic
VPS28 YPL065W Component of the ESCRT-I complex genetic 2 2 2 Dosage Rescue, Negative Genetic
VPS36 YLR417W Component of the ESCRT-II complex genetic 2 2 2 Dosage Rescue, Negative Genetic
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 2 1 2 Negative Genetic, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 2 1 2 Negative Genetic, Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 2 Negative Genetic, Negative Genetic
IOC3 YFR013W Subunit of the Isw1a complex genetic 2 1 2 Negative Genetic, Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 2 1 2 Negative Genetic, Negative Genetic
ATG3 YNR007C E2-like enzyme genetic 2 1 2 Negative Genetic, Negative Genetic
AIM17 YHL021C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes genetic 2 1 2 Negative Genetic, Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
DIA2 YOR080W Origin-binding F-box protein genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 2 1 2 Negative Genetic, Negative Genetic
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 2 1 2 Negative Genetic, Negative Genetic
PKH1 YDR490C Serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 2 1 2 Positive Genetic, Positive Genetic
ERC1 YHR032W Member of the multi-drug and toxin extrusion (MATE) family genetic 2 1 2 Negative Genetic, Negative Genetic
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 2 1 2 Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 2 1 2 Negative Genetic, Negative Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 2 1 2 Negative Genetic, Negative Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 2 1 2 Negative Genetic, Negative Genetic
ELO3 YLR372W Elongase genetic 2 1 2 Negative Genetic, Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 2 1 2 Negative Genetic, Negative Genetic
LRG1 YDL240W GTPase-activating protein (GAP) genetic 2 1 2 Negative Genetic, Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 2 1 2 Negative Genetic, Negative Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 2 1 2 Negative Genetic, Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 2 1 2 Negative Genetic, Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 2 1 2 Negative Genetic, Negative Genetic
ERG2 YMR202W C-8 sterol isomerase genetic 2 1 2 Negative Genetic, Negative Genetic
GDA1 YEL042W Guanosine diphosphatase located in the Golgi genetic 2 1 2 Negative Genetic, Negative Genetic
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 2 1 2 Negative Genetic, Negative Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
TSC13 YDL015C Enoyl reductase genetic 2 1 2 Negative Genetic, Negative Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 2 Negative Genetic, Negative Genetic
YPI1 YFR003C Regulatory subunit of the type I protein phosphatase (PP1) Glc7p genetic 2 1 2 Negative Genetic, Negative Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
RPL24B YGR148C Ribosomal 60S subunit protein L24B genetic 2 1 2 Negative Genetic, Negative Genetic
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) genetic 2 1 2 Negative Genetic, Negative Genetic
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease genetic 2 1 2 Negative Genetic, Negative Genetic
YET1 YKL065C Endoplasmic reticulum transmembrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 2 1 2 Negative Genetic, Negative Genetic
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 2 1 2 Negative Genetic, Negative Genetic
VTA1 YLR181C Multivesicular body (MVB) protein genetic 2 1 2 Negative Genetic, Negative Genetic
YLR407W YLR407W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 2 1 2 Negative Genetic, Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
PMS1 YNL082W ATP-binding protein required for mismatch repair genetic 2 1 2 Negative Genetic, Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 2 1 2 Negative Genetic, Negative Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 2 1 2 Positive Genetic, Positive Genetic
SIL1 YOL031C Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p genetic 2 1 2 Negative Genetic, Negative Genetic
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p genetic 2 1 2 Negative Genetic, Negative Genetic
YPL216W YPL216W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
TIP41 YPR040W Tap42p-interacting protein genetic 2 1 2 Negative Genetic, Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 2 1 2 Negative Genetic, Negative Genetic
UTH1 YKR042W Mitochondrial inner membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 2 1 2 Negative Genetic, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 2 1 2 Negative Genetic, Negative Genetic
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex genetic 2 1 2 Negative Genetic, Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 2 1 2 Negative Genetic, Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 2 1 2 Negative Genetic, Negative Genetic
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor genetic 2 1 2 Negative Genetic, Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 2 1 2 Negative Genetic, Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 2 1 2 Negative Genetic, Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 2 1 2 Negative Genetic, Negative Genetic
SEC4 YFL005W Rab family GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
VPS55 YJR044C Late endosomal protein involved in late endosome to vacuole transport genetic 2 1 2 Negative Genetic, Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 2 1 2 Negative Genetic, Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 2 1 2 Negative Genetic, Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 2 1 2 Negative Genetic, Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 2 1 2 Negative Genetic, Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 2 1 2 Negative Genetic, Negative Genetic
OPY2 YPR075C Integral membrane protein that acts as a membrane anchor for Ste50p genetic 2 1 2 Negative Genetic, Negative Genetic
DGR2 YKL121W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
MRX3 YBL095W Protein that associates with mitochondrial ribosome genetic 2 1 2 Negative Genetic, Negative Genetic
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
LIP1 YMR298W Ceramide synthase subunit genetic 2 1 2 Negative Genetic, Negative Genetic
LDO45 YMR147W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
AIM32 YML050W 2Fe-2S mitochondrial protein involved in redox quality control genetic 2 1 2 Negative Genetic, Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 2 1 2 Negative Genetic, Negative Genetic
CNE1 YAL058W Calnexin genetic 2 1 2 Negative Genetic, Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 2 1 2 Negative Genetic, Negative Genetic
MME1 YMR166C Transporter of the mitochondrial inner membrane that exports magnesium genetic 2 1 2 Negative Genetic, Negative Genetic
GDI1 YER136W GDP dissociation inhibitor genetic 2 2 1 Phenotypic Suppression, Dosage Lethality
SEC13 YLR208W Structural component of 3 complexes genetic 2 2 1 Phenotypic Suppression, Dosage Lethality
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 2 2 1 Phenotypic Suppression, Dosage Lethality
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex genetic 2 2 1 Phenotypic Suppression, Dosage Lethality
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex genetic 2 2 1 Phenotypic Suppression, Dosage Lethality
YPT1 YFL038C Rab family GTPase genetic 2 2 1 Phenotypic Suppression, Dosage Lethality
RAD53 YPL153C DNA damage response kinase genetic 2 2 1 Synthetic Rescue, Phenotypic Enhancement
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 2 2 1 Phenotypic Suppression, Phenotypic Enhancement
DIT1 YDR403W Sporulation-specific enzyme required for spore wall maturation genetic 2 2 1 Negative Genetic, Positive Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
EMP24 YGL200C Component of the p24 complex genetic 2 1 1 Negative Genetic, Negative Genetic
ERP1 YAR002C-A Member of the p24 family involved in ER to Golgi transport genetic 2 1 1 Positive Genetic, Positive Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 2 1 1 Negative Genetic, Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
ARF2 YDL137W ADP-ribosylation factor genetic 2 1 1 Negative Genetic, Negative Genetic
MMS4 YBR098W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 2 1 1 Negative Genetic, Negative Genetic
FAR3 YMR052W Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
LPP1 YDR503C Lipid phosphate phosphatase genetic 2 1 1 Positive Genetic, Positive Genetic
MVP1 YMR004W Protein required for sorting proteins to the vacuole genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
PHO80 YOL001W Cyclin genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
EMC1 YCL045C Member of conserved endoplasmic reticulum membrane complex genetic 2 1 1 Negative Genetic, Negative Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 2 1 1 Positive Genetic, Positive Genetic
GTA1 YEL043W Protein of unknown function genetic 2 1 1 Positive Genetic, Positive Genetic
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 2 1 1 Negative Genetic, Negative Genetic
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER genetic 2 1 1 Negative Genetic, Negative Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Negative Genetic, Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 2 1 1 Negative Genetic, Negative Genetic
YIP3 YNL044W Protein localized to COPII vesicles genetic 2 1 1 Negative Genetic, Negative Genetic
VAB2 YEL005C Subunit of the BLOC-1 complex involved in endosomal maturation genetic 2 1 1 Negative Genetic, Negative Genetic
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 2 1 1 Negative Genetic, Negative Genetic
SCJ1 YMR214W One of several homologs of bacterial chaperone DnaJ genetic 2 1 1 Negative Genetic, Negative Genetic
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p genetic 2 1 1 Negative Genetic, Negative Genetic
YDR222W YDR222W Protein of unknown function genetic 2 1 1 Positive Genetic, Positive Genetic
YPS7 YDR349C Putative GPI-anchored aspartic protease genetic 2 1 1 Positive Genetic, Positive Genetic
YPR148C YPR148C Protein of unknown function genetic 2 1 1 Positive Genetic, Positive Genetic
SFT2 YBL102W Tetra-spanning membrane protein found mostly in the late Golgi genetic 2 1 1 Positive Genetic, Positive Genetic
RCE1 YMR274C Type II CAAX prenyl protease genetic 2 1 1 Positive Genetic, Positive Genetic
TMS1 YDR105C Vacuolar membrane protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
YDR124W YDR124W Mitochondrial protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
RNP1 YLL046C Ribonucleoprotein that contains two RNA recognition motifs (RRM) genetic 2 1 1 Negative Genetic, Negative Genetic
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 2 1 1 Negative Genetic, Negative Genetic
RPS30B YOR182C Protein component of the small (40S) ribosomal subunit genetic 2 1 1 Negative Genetic, Negative Genetic
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 2 1 1 Positive Genetic, Positive Genetic
TRE1 YPL176C Transferrin receptor-like protein genetic 2 1 1 Negative Genetic, Negative Genetic
SSH1 YBR283C Subunit of the Ssh1 translocon complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
UBC7 YMR022W Ubiquitin conjugating enzyme genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
YJL193W YJL193W Putative protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 2 1 1 Negative Genetic, Negative Genetic
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 2 1 1 Negative Genetic, Negative Genetic
DER1 YBR201W ER membrane protein that promotes export of misfolded polypeptides genetic 2 1 1 Negative Genetic, Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 2 1 1 Positive Genetic, Positive Genetic
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
OPT1 YJL212C Proton-coupled oligopeptide transporter of the plasma membrane genetic 2 1 1 Positive Genetic, Positive Genetic
ALE1 YOR175C Broad-specificity lysophospholipid acyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 2 1 1 Positive Genetic, Positive Genetic
FRE7 YOL152W Putative ferric reductase with similarity to Fre2p genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Positive Genetic
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs genetic 1 1 1 Negative Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
AXL2 YIL140W Integral plasma membrane protein genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
LTO1 YNL260C Substrate-specific adaptor protein involved in apo-Rli1p maturation genetic 1 1 1 Negative Genetic
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Negative Genetic
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex genetic 1 1 1 Negative Genetic
HCA4 YJL033W DEAD box RNA helicase genetic 1 1 1 Negative Genetic
MDM20 YOL076W Non-catalytic subunit of the NatB N-terminal acetyltransferase genetic 1 1 1 Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Negative Genetic
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
GCD2 YGR083C Delta subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Negative Genetic
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Negative Genetic
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme genetic 1 1 1 Negative Genetic
ATG14 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I physical 1 1 1 Affinity Capture-MS
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARC40 YBR234C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
CAP1 YKL007W Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 1 1 1 Synthetic Growth Defect
CAF40 YNL288W Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
ERG26 YGL001C C-3 sterol dehydrogenase genetic 1 1 1 Negative Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Negative Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Synthetic Growth Defect
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly genetic 1 1 1 Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Negative Genetic
FYV4 YHR059W Protein of unknown function genetic 1 1 1 Negative Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Positive Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Synthetic Rescue
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Positive Genetic
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions genetic 1 1 1 Negative Genetic
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Negative Genetic
MLC2 YPR188C Regulatory light chain for the type II myosin Myo1p genetic 1 1 1 Negative Genetic
MYO1 YHR023W Type II myosin heavy chain physical 1 1 1 Affinity Capture-MS
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Negative Genetic
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Positive Genetic
NHP6B YBR089C-A High-mobility group (HMG) protein genetic 1 1 1 Negative Genetic
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
DOA4 YDR069C Ubiquitin hydrolase genetic 1 1 1 Negative Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
FYV8 YGR196C Protein of unknown function genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles physical 1 1 1 Affinity Capture-MS
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Synthetic Growth Defect
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Synthetic Rescue
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Positive Genetic
ECM30 YLR436C Protein of unknown function genetic 1 1 1 Positive Genetic
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
NTE1 YML059C Serine esterase genetic 1 1 1 Negative Genetic
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Negative Genetic
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton genetic 1 1 1 Negative Genetic
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Phenotypic Enhancement
LAM5 YFL042C Putative sterol transfer protein genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
ATG31 YDR022C Autophagy-specific protein required for autophagosome formation physical 1 1 1 Affinity Capture-MS
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator physical 1 1 1 Affinity Capture-MS
CNB1 YKL190W Calcineurin B genetic 1 1 1 Negative Genetic
HSH49 YOR319W U2-snRNP associated splicing factor genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
PDI1 YCL043C Protein disulfide isomerase genetic 1 1 1 Negative Genetic
HXT7 YDR342C High-affinity glucose transporter physical 1 1 1 Affinity Capture-MS
PDC6 YGR087C Minor isoform of pyruvate decarboxylase genetic 1 1 1 Negative Genetic
ATG11 YPR049C Adapter protein for pexophagy and the Cvt targeting pathway physical 1 1 1 Affinity Capture-MS
ECM10 YEL030W Heat shock protein of the Hsp70 family genetic 1 1 1 Negative Genetic
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
ILV3 YJR016C Dihydroxyacid dehydratase genetic 1 1 1 Negative Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Positive Genetic
MLH3 YPL164C Protein involved in DNA mismatch repair and meiotic recombination genetic 1 1 1 Negative Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Negative Genetic
KNS1 YLL019C Protein kinase involved in negative regulation of PolIII transcription genetic 1 1 1 Positive Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Negative Genetic
PBA1 YLR199C Protein involved in 20S proteasome assembly genetic 1 1 1 Negative Genetic
GIS4 YML006C CAAX box containing protein of unknown function genetic 1 1 1 Negative Genetic
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Negative Genetic
ASR1 YPR093C Ubiquitin ligase that modifies and regulates RNA Pol II genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Positive Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
MGT1 YDL200C DNA repair methyltransferase (6-O-methylguanine-DNA methylase) genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 1 1 1 Negative Genetic
GLG2 YJL137C Glycogenin glucosyltransferase genetic 1 1 1 Negative Genetic
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex physical 1 1 1 Affinity Capture-MS
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex genetic 1 1 1 Negative Genetic
DAL82 YNL314W Positive regulator of allophanate inducible genes genetic 1 1 1 Negative Genetic
ENT3 YJR125C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Negative Genetic
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Dosage Growth Defect
LST7 YGR057C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Positive Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
ALY2 YJL084C Alpha arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Synthetic Rescue
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway physical 1 1 1 Affinity Capture-MS
JSN1 YJR091C Member of the Puf family of RNA-binding proteins genetic 1 1 1 Negative Genetic
DLS1 YJL065C Subunit of ISW2/yCHRAC chromatin accessibility complex genetic 1 1 1 Negative Genetic
LDB17 YDL146W Protein involved in the regulation of endocytosis genetic 1 1 1 Negative Genetic
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
LAA2 YBL010C Clathrin adaptor (adaptin) accessory protein genetic 1 1 1 Negative Genetic
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
AMD1 YML035C AMP deaminase genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
ATG23 YLR431C Peripheral membrane protein required for autophagy and CVT physical 1 1 1 Affinity Capture-MS
ATG8 YBL078C Ub-like protein physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Positive Genetic
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion genetic 1 1 1 Negative Genetic
MYO5 YMR109W One of two type I myosin motors genetic 1 1 1 Negative Genetic
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 1 1 1 Negative Genetic
FIG4 YNL325C Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase genetic 1 1 1 Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Negative Genetic
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation physical 1 1 1 Affinity Capture-MS
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
OST6 YML019W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system physical 1 1 1 Co-localization
GAP1 YKR039W General amino acid permease physical 1 1 1 Co-localization
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Positive Genetic
MSO1 YNR049C Lipid-interacting protein in SNARE complex assembly machinery genetic 1 1 1 Negative Genetic
CAF16 YFL028C Part of evolutionarily-conserved CCR4-NOT regulatory complex genetic 1 1 1 Positive Genetic
CHS3 YBR023C Chitin synthase III genetic 1 1 1 Negative Genetic
AFI1 YOR129C Arf3p polarization-specific docking factor genetic 1 1 1 Negative Genetic
BCH1 YMR237W Member of the ChAPs family (Chs5p-Arf1p-binding proteins) genetic 1 1 1 Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Dosage Rescue
DFG5 YMR238W Putative mannosidase genetic 1 1 1 Negative Genetic
MSB3 YNL293W Rab GTPase-activating protein genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Positive Genetic
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Positive Genetic
HPA2 YPR193C Tetrameric histone acetyltransferase genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Synthetic Growth Defect
PAN3 YKL025C Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 1 1 1 Synthetic Growth Defect
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) physical 1 1 1 Affinity Capture-MS
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Positive Genetic
CLB3 YDL155W B-type cyclin involved in cell cycle progression genetic 1 1 1 Dosage Lethality
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Positive Genetic
GDH3 YAL062W NADP(+)-dependent glutamate dehydrogenase genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Positive Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Positive Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Negative Genetic
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 1 1 1 Positive Genetic
CAT2 YML042W Carnitine acetyl-CoA transferase genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
FRK1 YPL141C Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
DDR2 YOL052C-A Multi-stress response protein genetic 1 1 1 Negative Genetic
ERI1 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p genetic 1 1 1 Negative Genetic
KRE2 YDR483W Alpha1,2-mannosyltransferase of the Golgi genetic 1 1 1 Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Synthetic Growth Defect
NSI1 YDR026C RNA polymerase I termination factor genetic 1 1 1 Negative Genetic
COQ11 YLR290C Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes genetic 1 1 1 Positive Genetic
YAR010C YAR010C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Affinity Capture-MS
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
SED5 YLR026C cis-Golgi t-SNARE syntaxin physical 1 1 1 Co-purification
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 PCA
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II physical 1 1 1 Affinity Capture-MS
VPS15 YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting physical 1 1 1 Affinity Capture-MS
SEC13 YLR208W Structural component of 3 complexes physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER physical 1 1 1 PCA
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-RNA
SMF2 YHR050W Divalent metal ion transporter involved in manganese homeostasis genetic 1 1 1 Phenotypic Enhancement
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Synthetic Growth Defect
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 1 1 1 Dosage Lethality
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex genetic 1 1 1 Dosage Lethality
SEC53 YFL045C Phosphomannomutase genetic 1 1 1 Dosage Lethality
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Synthetic Growth Defect
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase genetic 1 1 1 Synthetic Growth Defect
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Growth Defect
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Synthetic Growth Defect
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Synthetic Growth Defect
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Synthetic Growth Defect
VCX1 YDL128W Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity genetic 1 1 1 Synthetic Lethality
YVC1 YOR087W Vacuolar cation channel genetic 1 1 1 Phenotypic Suppression
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Growth Defect
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 1 1 1 Negative Genetic
SDD1 YEL057C Protein of unknown function genetic 1 1 1 Negative Genetic
YPT31 YER031C Rab family GTPase genetic 1 1 1 Negative Genetic
YMR31 YFR049W Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase genetic 1 1 1 Negative Genetic
YCR043C YCR043C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YFL051C YFL051C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TIM21 YGR033C Nonessential component of the TIM23 complex genetic 1 1 1 Negative Genetic
YGR122W YGR122W Protein that may be involved in pH regulation genetic 1 1 1 Positive Genetic
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SFH5 YJL145W Unusual phosphatidylinositol transfer protein (PITP) that binds heme genetic 1 1 1 Negative Genetic
PRM10 YJL108C Pheromone-regulated protein genetic 1 1 1 Negative Genetic
YHC3 YJL059W Protein required for the ATP-dependent transport of arginine genetic 1 1 1 Negative Genetic
TPH3 YJL016W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YJR098C YJR098C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YLR415C YLR415C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YGK3 YOL128C Protein kinase related to mammalian GSK-3 glycogen synthase kinases genetic 1 1 1 Negative Genetic
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases genetic 1 1 1 Negative Genetic
YPR172W YPR172W Protein of unknown function genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Rescue
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Positive Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Positive Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
SCD5 YOR329C Protein required for normal actin organization and endocytosis genetic 1 1 1 Negative Genetic
VNX1 YNL321W Calcium/H+ antiporter localized to the endoplasmic reticulum membrane genetic 1 1 1 Phenotypic Enhancement
RAD55 YDR076W Protein that stimulates strand exchange genetic 1 1 1 Synthetic Growth Defect
RAD18 YCR066W E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
YCF1 YDR135C Vacuolar glutathione S-conjugate transporter genetic 1 1 1 Synthetic Rescue
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Positive Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Positive Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Positive Genetic
VMA11 YPL234C Vacuolar ATPase V0 domain subunit c' genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Positive Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
RLM1 YPL089C MADS-box transcription factor genetic 1 1 1 Negative Genetic
SEC59 YMR013C Dolichol kinase genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
SPT14 YPL175W UDP-glycosyltransferase subunit of the GPI-GnT complex genetic 1 1 1 Negative Genetic
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
PRE3 YJL001W Beta 1 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SLX4 YLR135W Endonuclease involved in processing DNA genetic 1 1 1 Negative Genetic
SNF7 YLR025W One of four subunits of the ESCRT-III complex genetic 1 1 1 Dosage Rescue
SNF8 YPL002C Component of the ESCRT-II complex genetic 1 1 1 Dosage Rescue
VPS25 YJR102C Component of the ESCRT-II complex genetic 1 1 1 Dosage Rescue
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Positive Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Positive Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Positive Genetic
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Positive Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Positive Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Positive Genetic
POP5 YAL033W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
POP4 YBR257W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
RPC11 YDR045C RNA polymerase III subunit C11 genetic 1 1 1 Negative Genetic
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) genetic 1 1 1 Negative Genetic
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Negative Genetic
PRE1 YER012W Beta 4 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Negative Genetic
YPP1 YGR198W Cargo-transport protein involved in endocytosis genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Negative Genetic
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) genetic 1 1 1 Negative Genetic
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Negative Genetic
YAE1 YJR067C Substrate-specific adaptor protein involved in apo-Rli1p maturation genetic 1 1 1 Negative Genetic
URA6 YKL024C Uridylate kinase genetic 1 1 1 Negative Genetic
PRI2 YKL045W Subunit of DNA primase genetic 1 1 1 Negative Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 1 1 1 Negative Genetic
TIF11 YMR260C Translation initiation factor eIF1A genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
RPC31 YNL151C RNA polymerase III subunit C31 genetic 1 1 1 Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Negative Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Negative Genetic
RKI1 YOR095C Ribose-5-phosphate ketol-isomerase genetic 1 1 1 Negative Genetic
SME1 YOR159C Core Sm protein Sm E genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RPA43 YOR340C RNA polymerase I subunit A43 genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
TAF3 YPL011C TFIID subunit (47 kDa) genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
RPC82 YPR190C RNA polymerase III subunit C82 genetic 1 1 1 Negative Genetic
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 1 1 1 Negative Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
YBR298C-A YBR298C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YCP4 YCR004C Protein of unknown function genetic 1 1 1 Negative Genetic
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Negative Genetic
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Negative Genetic
UGA4 YDL210W GABA (gamma-aminobutyrate) permease genetic 1 1 1 Negative Genetic
YDR003W-A YDR003W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TFB5 YDR079C-A Component of RNA polymerase II general transcription factor TFIIH genetic 1 1 1 Negative Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Negative Genetic
SNX41 YDR425W Sorting nexin genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
YDL180W YDL180W Putative protein of unknown function genetic 1 1 1 Negative Genetic
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
SSH4 YKL124W Specificity factor required for Rsp5p-dependent ubiquitination genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
RPS1B YML063W Ribosomal protein of the small (40S) subunit genetic 1 1 1 Negative Genetic
YNL143C YNL143C Protein of unknown function genetic 1 1 1 Negative Genetic
YOR008C-A YOR008C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RCN2 YOR220W Protein of unknown function genetic 1 1 1 Negative Genetic
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Negative Genetic
YHR050W-A YHR050W-A Protein of unknown function genetic 1 1 1 Negative Genetic
SIM1 YIL123W Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) genetic 1 1 1 Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
YJR149W YJR149W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TCD2 YKL027W tRNA threonylcarbamoyladenosine dehydratase genetic 1 1 1 Negative Genetic
YPT52 YKR014C Endosomal Rab family GTPase genetic 1 1 1 Negative Genetic
TVP38 YKR088C Integral membrane protein genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
YLR419W YLR419W Putative helicase with limited sequence similarity to human Rb protein genetic 1 1 1 Negative Genetic
YML037C YML037C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL15B YMR121C Ribosomal 60S subunit protein L15B genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
SLY41 YOR307C Protein involved in ER-to-Golgi transport genetic 1 1 1 Synthetic Growth Defect
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Negative Genetic
YOL013W-A YOL013W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein genetic 1 1 1 Negative Genetic
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
YPR114W YPR114W Protein distantly similar to ceramide synthases, Lag1p and Lac1p genetic 1 1 1 Negative Genetic
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Phenotypic Enhancement
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Negative Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 1 1 1 Negative Genetic
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
SDH2 YLL041C Iron-sulfur protein subunit of succinate dehydrogenase genetic 1 1 1 Positive Genetic
RCH1 YMR034C Negative regulator of cytosolic calcium homeostasis genetic 1 1 1 Dosage Rescue
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Positive Genetic
YIL161W YIL161W Putative protein of unknown function genetic 1 1 1 Positive Genetic
RPL38 YLR325C Ribosomal 60S subunit protein L38 genetic 1 1 1 Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling genetic 1 1 1 Positive Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Negative Genetic
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p genetic 1 1 1 Negative Genetic
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Positive Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy physical 1 1 1 Affinity Capture-MS
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
IRC8 YJL051W Bud tip localized protein of unknown function genetic 1 1 1 Negative Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
MBR1 YKL093W Protein involved in mitochondrial functions and stress response genetic 1 1 1 Negative Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Negative Genetic
NQM1 YGR043C Transaldolase of unknown function genetic 1 1 1 Negative Genetic
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Synthetic Rescue
GLN4 YOR168W Glutamine tRNA synthetase genetic 1 1 1 Negative Genetic
MRPL32 YCR003W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
PFK26 YIL107C 6-phosphofructo-2-kinase genetic 1 1 1 Negative Genetic
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs genetic 1 1 1 Positive Genetic
GEP5 YLR091W Protein of unknown function genetic 1 1 1 Positive Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) physical 1 1 1 Affinity Capture-MS
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Positive Genetic
GAA1 YLR088W Subunit of the GPI:protein transamidase complex genetic 1 1 1 Negative Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Synthetic Lethality
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
HUT1 YPL244C Protein with a role in UDP-galactose transport to the Golgi lumen genetic 1 1 1 Positive Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
ENT4 YLL038C Protein of unknown function genetic 1 1 1 Negative Genetic
ORM1 YGR038W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
NVJ2 YPR091C Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) genetic 1 1 1 Negative Genetic
EMC4 YGL231C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
AIM39 YOL053W Protein of unknown function genetic 1 1 1 Positive Genetic
PAU22 YPL282C Protein of unknown function genetic 1 1 1 Negative Genetic
CHS7 YHR142W Protein of unknown function genetic 1 1 1 Negative Genetic
PCK1 YKR097W Phosphoenolpyruvate carboxykinase genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
MNN5 YJL186W Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
GSC2 YGR032W Catalytic subunit of 1,3-beta-glucan synthase genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
GIS1 YDR096W Histone demethylase and transcription factor genetic 1 1 1 Negative Genetic
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Negative Genetic
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
NPR1 YNL183C Protein kinase genetic 1 1 1 Dosage Rescue
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
COM2 YER130C Transcription factor that binds IME1 Upstream Activation Signal (UAS) genetic 1 1 1 Negative Genetic
NOP10 YHR072W-A Subunit of box H/ACA snoRNP complex genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Positive Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Positive Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
DCW1 YKL046C Putative mannosidase genetic 1 1 1 Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Negative Genetic
FIT2 YOR382W Mannoprotein that is incorporated into the cell wall genetic 1 1 1 Negative Genetic
IML2 YJL082W Protein required for clearance of inclusion bodies genetic 1 1 1 Negative Genetic
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Positive Genetic
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 1 1 1 Negative Genetic
PCA1 YBR295W Cadmium transporting P-type ATPase genetic 1 1 1 Negative Genetic
GRX6 YDL010W Cis-Golgi localized monothiol glutaredoxin, binds Fe-S cluster genetic 1 1 1 Phenotypic Enhancement
FMP30 YPL103C Protein with a role in maintaining mitochondrial morphology genetic 1 1 1 Positive Genetic
HMX1 YLR205C ER localized heme oxygenase genetic 1 1 1 Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Positive Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Negative Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Negative Genetic
CIS1 YLR346C Protein of unknown function found in mitochondria genetic 1 1 1 Negative Genetic
FSH1 YHR049W Lysophospholipase genetic 1 1 1 Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Negative Genetic
DAL7 YIR031C Malate synthase genetic 1 1 1 Negative Genetic
NIT2 YJL126W Nit protein genetic 1 1 1 Negative Genetic
FMT1 YBL013W Methionyl-tRNA formyltransferase genetic 1 1 1 Negative Genetic
NCA3 YJL116C Protein involved in mitochondrion organization genetic 1 1 1 Negative Genetic
FYV12 YOR183W Protein of unknown function genetic 1 1 1 Negative Genetic