GEnome-wide tool for Multi-scale Modeling
data Extraction and Representation
for Saccharomyces cerevisiae

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.

Standard name	Systematic name	Name description	Type	#Experiments	#Methods	#Publications	Evidence
SHP1	YBL058W	UBX domain-containing substrate adaptor for Cdc48p	physical	24	5	14	Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-MS, Affinity Capture-Western
DOA1	YKL213C	WD-repeat protein involved in ubiquitin-mediated protein degradation	physical	23	6	12	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Co-purification, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Protein-peptide, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western
NPL4	YBR170C	Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase	physical	21	4	15	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western
UFD2	YDL190C	Ubiquitin (Ub) chain assembly factor (E4)	physical	20	6	11	Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Protein-peptide, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
UFD1	YGR048W	Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase	physical	19	3	14	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
UBX2	YML013W	Bridging factor involved in ER-associated protein degradation (ERAD)	physical	17	3	12	Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
VMS1	YDR049W	Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes,	physical	14	4	10	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification
UBX4	YMR067C	UBX domain-containing protein that interacts with Cdc48p	physical	10	4	6	Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
UBI4	YLL039C	Ubiquitin	physical	9	4	9	Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Co-localization, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex
HRD1	YOL013C	Ubiquitin-protein ligase involved in ER-associated degradation (ERAD)	physical	9	3	9	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
OTU1	YFL044C	Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p	physical	9	4	7	Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Affinity Capture-Western
UBX7	YBR273C	UBX (ubiquitin regulatory X) domain-containing protein	physical	9	4	4	Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
UBX3	YDL091C	Clathrin-coated vesicle component, regulator of endocytosis	physical	7	4	5	Two-hybrid, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
CUZ1	YNL155W	Protein with a role in the ubiquitin-proteasome pathway	physical	7	4	5	Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex
SGS1	YMR190C	RecQ family nucleolar DNA helicase	genetic	7	4	5	Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Positive Genetic
UBX5	YDR330W	UBX domain-containing protein that interacts with Cdc48p	physical	7	4	4	Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
UBX4	YMR067C	UBX domain-containing protein that interacts with Cdc48p	genetic	6	4	5	Negative Genetic, Dosage Rescue, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Rescue
WSS1	YHR134W	SUMO-ligase and SUMO-targeted metalloprotease	physical	6	4	2	Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Biochemical Activity
DFM1	YDR411C	Endoplasmic reticulum (ER) localized protein	physical	5	3	4	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
DSK2	YMR276W	Nuclear-enriched ubiquitin-like polyubiquitin-binding protein	genetic	5	3	4	Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Synthetic Growth Defect
FZO1	YBR179C	Mitofusin, protein involved in mitochondrial outer membrane fusion	physical	5	1	4	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RFU1	YLR073C	Protein that inhibits Doa4p deubiquitinating activity	genetic	5	4	3	Dosage Rescue, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic, Negative Genetic
UBX6	YJL048C	UBX (ubiquitin regulatory X) domain-containing protein	physical	5	3	3	Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western
HMG2	YLR450W	HMG-CoA reductase	physical	5	2	3	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
VMS1	YDR049W	Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes,	genetic	4	3	4	Negative Genetic, Dosage Rescue, Synthetic Growth Defect, Negative Genetic
RPN4	YDL020C	Transcription factor that stimulates expression of proteasome genes	genetic	4	3	4	Negative Genetic, Dosage Rescue, Dosage Rescue, Synthetic Lethality
SSM4	YIL030C	Membrane-embedded ubiquitin-protein ligase and retrotranslocase	physical	4	2	4	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RPN11	YFR004W	Metalloprotease subunit of 19S regulatory particle	physical	4	2	4	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
UBP3	YER151C	Ubiquitin-specific protease that cleaves Ub-protein fusions	genetic	4	3	3	Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Rescue
RPN10	YHR200W	Proteasome polyubiquitin receptor	genetic	4	2	3	Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality
LGE1	YPL055C	Protein involved in histone H2B ubiquitination	genetic	4	2	3	Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect
CTF4	YPR135W	Chromatin-associated protein	genetic	4	2	3	Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
HSL1	YKL101W	Nim1p-related protein kinase	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
THI7	YLR237W	Plasma membrane transporter responsible for the uptake of thiamine	genetic	4	2	2	Negative Genetic, Positive Genetic, Negative Genetic, Negative Genetic
POC4	YPL144W	Component of a heterodimeric Poc4p-Irc25p chaperone	genetic	4	2	2	Negative Genetic, Positive Genetic, Negative Genetic, Negative Genetic
BRE5	YNR051C	Ubiquitin protease cofactor	physical	4	2	2	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
INO80	YGL150C	Nucleosome spacing factor	physical	4	3	1	Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS
STT3	YGL022W	Catalytic subunit of the oligosaccharyltransferase complex of the ER l	genetic	4	2	1	Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
CDC48	YDL126C	AAA ATPase with protein-unfoldase activity	physical	3	3	3	Two-hybrid, Affinity Capture-MS, Co-purification
UBP2	YOR124C	Ubiquitin-specific protease	genetic	3	3	3	Negative Genetic, Synthetic Rescue, Dosage Rescue
CLN2	YPL256C	G1 cyclin involved in regulation of the cell cycle	genetic	3	2	3	Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
RAD23	YEL037C	Protein with ubiquitin-like N terminus	genetic	3	2	3	Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect
DER1	YBR201W	ER membrane protein that promotes export of misfolded polypeptides	physical	3	2	3	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
SSM4	YIL030C	Membrane-embedded ubiquitin-protein ligase and retrotranslocase	genetic	3	2	3	Positive Genetic, Phenotypic Enhancement, Positive Genetic
UBR2	YLR024C	Cytoplasmic ubiquitin-protein ligase (E3)	genetic	3	2	3	Positive Genetic, Positive Genetic, Synthetic Rescue
RTT107	YHR154W	BRCA1 C-terminal domain protein needed for recovery from DNA damage	genetic	3	2	3	Negative Genetic, Positive Genetic, Negative Genetic
HRD3	YLR207W	ER membrane protein that plays a central role in ERAD	physical	3	1	3	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
SSA1	YAL005C	ATPase involved in protein folding and NLS-directed nuclear transport	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
LSM1	YJL124C	Lsm (Like Sm) protein	genetic	3	1	3	Positive Genetic, Positive Genetic, Positive Genetic
ELM1	YKL048C	Serine/threonine protein kinase	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
UFE1	YOR075W	t-SNARE protein required for retrograde vesicular traffic	genetic	3	2	2	Dosage Rescue, Dosage Rescue, Phenotypic Suppression
RAD23	YEL037C	Protein with ubiquitin-like N terminus	physical	3	2	2	Affinity Capture-Western, Affinity Capture-Western, Two-hybrid
RQC1	YDR333C	Component of the ribosome quality control complex (RQC)	physical	3	2	2	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RQC2	YPL009C	Component of the Ribosome Quality Control (RQC) complex	physical	3	2	2	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RSP5	YER125W	NEDD4 family E3 ubiquitin ligase	genetic	3	2	2	Synthetic Lethality, Negative Genetic, Negative Genetic
RPT4	YOR259C	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	3	2	2	Phenotypic Suppression, Negative Genetic, Negative Genetic
ORC2	YBR060C	Subunit of the origin recognition complex (ORC)	genetic	3	2	2	Dosage Rescue, Positive Genetic, Positive Genetic
MRC1	YCL061C	S-phase checkpoint protein required for DNA replication	genetic	3	2	2	Synthetic Growth Defect, Negative Genetic, Negative Genetic
PRE4	YFR050C	Beta 7 subunit of the 20S proteasome	genetic	3	2	2	Negative Genetic, Negative Genetic, Synthetic Rescue
STE6	YKL209C	Plasma membrane ATP-binding cassette (ABC) transporter	physical	3	1	2	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
MMS22	YLR320W	Subunit of E3 ubiquitin ligase complex involved in replication repair	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
UBP12	YJL197W	Ubiquitin-specific protease	physical	3	1	2	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
ESC2	YDR363W	Sumo-like domain protein	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SEM1	YDR363W-A	19S proteasome regulatory particle lid subcomplex component	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SDC1	YDR469W	Subunit of the COMPASS (Set1C) complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
HAC1	YFL031W	Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PRE9	YGR135W	Alpha 3 subunit of the 20S proteasome	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CHO2	YGR157W	Phosphatidylethanolamine methyltransferase (PEMT)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
NPR3	YHL023C	Subunit of the Iml1p/SEACIT complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
IRC25	YLR021W	Component of a heterodimeric Poc4p-Irc25p chaperone	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SIN3	YOL004W	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
XRS2	YDR369C	FHA domain-containing component of the Mre11 complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RLF2	YPR018W	Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SWM1	YDR260C	Subunit of the anaphase-promoting complex (APC)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RRM3	YHR031C	DNA helicase involved in rDNA replication and Ty1 transposition	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SDS3	YIL084C	Component of the Rpd3L histone deacetylase complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RTT101	YJL047C	Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RTT109	YLL002W	Histone acetyltransferase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
NUP188	YML103C	Subunit of the inner ring of the nuclear pore complex (NPC)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MRE11	YMR224C	Nuclease subunit of the MRX complex with Rad50p and Xrs2p	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SAP30	YMR263W	Component of Rpd3L histone deacetylase complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PHO23	YNL097C	Component of the Rpd3L histone deacetylase complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
ERG3	YLR056W	C-5 sterol desaturase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
BRE2	YLR015W	Subunit of COMPASS (Set1C) complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CAC2	YML102W	Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CLN2	YPL256C	G1 cyclin involved in regulation of the cell cycle	physical	3	2	1	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
UBP3	YER151C	Ubiquitin-specific protease that cleaves Ub-protein fusions	physical	3	2	1	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
RPT6	YGL048C	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	3	2	1	Positive Genetic, Negative Genetic, Negative Genetic
VPS27	YNR006W	Endosomal protein that forms a complex with Hse1p	genetic	3	2	1	Positive Genetic, Positive Genetic, Negative Genetic
ACT1	YFL039C	Actin, structural protein in cytoskeleton	genetic	3	2	1	Positive Genetic, Negative Genetic, Negative Genetic
ARP5	YNL059C	Nuclear actin-related protein involved in chromatin remodeling	physical	3	2	1	Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
SHP1	YBL058W	UBX domain-containing substrate adaptor for Cdc48p	genetic	2	2	2	Negative Genetic, Synthetic Rescue
UFD1	YGR048W	Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase	genetic	2	2	2	Synthetic Lethality, Negative Genetic
DOA1	YKL213C	WD-repeat protein involved in ubiquitin-mediated protein degradation	genetic	2	2	2	Synthetic Rescue, Positive Genetic
SMT3	YDR510W	Ubiquitin-like protein of the SUMO family	physical	2	2	2	Affinity Capture-MS, Reconstituted Complex
PRE1	YER012W	Beta 4 subunit of the 20S proteasome	physical	2	2	2	Affinity Capture-MS, Affinity Capture-Western
YGL108C	YGL108C	Protein of unknown function, predicted to be palmitoylated	physical	2	2	2	Affinity Capture-MS, Two-hybrid
USA1	YML029W	Scaffold subunit of the Hrd1p ubiquitin ligase	physical	2	2	2	Affinity Capture-MS, Affinity Capture-Western
RPN5	YDL147W	Subunit of the CSN and 26S proteasome lid complexes	physical	2	2	2	Affinity Capture-MS, Affinity Capture-Western
RPO21	YDL140C	RNA polymerase II largest subunit B220	physical	2	2	2	Affinity Capture-Western, Affinity Capture-MS
SEC23	YPR181C	GTPase-activating protein, stimulates the GTPase activity of Sar1p	physical	2	2	2	Affinity Capture-Western, Affinity Capture-MS
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	physical	2	2	2	Affinity Capture-MS, Affinity Capture-RNA
UBP12	YJL197W	Ubiquitin-specific protease	genetic	2	2	2	Negative Genetic, Synthetic Rescue
RPS8A	YBL072C	Protein component of the small (40S) ribosomal subunit	genetic	2	2	2	Dosage Rescue, Positive Genetic
DIA2	YOR080W	Origin-binding F-box protein	genetic	2	2	2	Negative Genetic, Synthetic Lethality
DGK1	YOR311C	Diacylglycerol kinase	genetic	2	2	2	Negative Genetic, Positive Genetic
GLC7	YER133W	Type 1 S/T protein phosphatase (PP1) catalytic subunit	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
PKC1	YBL105C	Protein serine/threonine kinase	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
UBC1	YDR177W	Ubiquitin-conjugating enzyme	genetic	2	2	2	Dosage Rescue, Negative Genetic
CDC73	YLR418C	Component of the Paf1p complex	genetic	2	2	2	Synthetic Lethality, Positive Genetic
RPO31	YOR116C	RNA polymerase III largest subunit C160	genetic	2	2	2	Negative Genetic, Synthetic Rescue
PAM17	YKR065C	Constituent of the TIM23 complex	genetic	2	2	2	Negative Genetic, Phenotypic Enhancement
YDJ1	YNL064C	Type I HSP40 co-chaperone	genetic	2	2	2	Negative Genetic, Phenotypic Suppression
GLE2	YER107C	RNA export factor associated with the nuclear pore complex (NPC)	genetic	2	2	2	Negative Genetic, Synthetic Growth Defect
UBP8	YMR223W	Ubiquitin-specific protease component of the SAGA acetylation complex	genetic	2	2	2	Negative Genetic, Phenotypic Suppression
ATG8	YBL078C	Ub-like protein	physical	2	2	2	Reconstituted Complex, Affinity Capture-MS
ADD37	YMR184W	Protein of unknown function	genetic	2	2	2	Dosage Rescue, Negative Genetic
MRPS28	YDR337W	Mitochondrial ribosomal protein of the small subunit	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RAI1	YGL246C	Nuclear decapping endonuclease	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
REG1	YDR028C	Regulatory subunit of type 1 protein phosphatase Glc7p	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
SPT23	YKL020C	ER membrane protein involved in regulation of OLE1 transcription	physical	2	1	2	Affinity Capture-Western, Affinity Capture-Western
MCA1	YOR197W	Ca2+-dependent cysteine protease	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
MET30	YIL046W	F-box protein containing five copies of the WD40 motif	physical	2	1	2	Affinity Capture-Western, Affinity Capture-Western
HSP82	YPL240C	Hsp90 chaperone	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
RPL16A	YIL133C	Ribosomal 60S subunit protein L16A	genetic	2	1	2	Positive Genetic, Positive Genetic
UBP2	YOR124C	Ubiquitin-specific protease	physical	2	1	2	Affinity Capture-Western, Affinity Capture-Western
ISW1	YBR245C	ATPase subunit of imitation-switch (ISWI) class chromatin remodelers	genetic	2	1	2	Negative Genetic, Negative Genetic
UME6	YDR207C	Rpd3L histone deacetylase complex subunit	genetic	2	1	2	Negative Genetic, Negative Genetic
CHD1	YER164W	Chromatin remodeler that regulates various aspects of transcription	genetic	2	1	2	Negative Genetic, Negative Genetic
UBP6	YFR010W	Ubiquitin-specific protease	genetic	2	1	2	Positive Genetic, Positive Genetic
GCN1	YGL195W	Positive regulator of the Gcn2p kinase activity	genetic	2	1	2	Negative Genetic, Negative Genetic
SCS3	YGL126W	Protein required for normal ER membrane biosynthesis in response to ER	genetic	2	1	2	Negative Genetic, Negative Genetic
SNF4	YGL115W	Activating gamma subunit of the AMP-activated Snf1p kinase complex	genetic	2	1	2	Negative Genetic, Negative Genetic
OCA5	YHL029C	Cytoplasmic protein required for replication of Brome mosaic virus	genetic	2	1	2	Negative Genetic, Negative Genetic
IRE1	YHR079C	Serine-threonine kinase and endoribonuclease	genetic	2	1	2	Negative Genetic, Negative Genetic
RPL43B	YJR094W-A	Ribosomal 60S subunit protein L43B	genetic	2	1	2	Positive Genetic, Positive Genetic
STE24	YJR117W	Highly conserved zinc metalloprotease	genetic	2	1	2	Negative Genetic, Negative Genetic
DBP7	YKR024C	Putative ATP-dependent RNA helicase of the DEAD-box family	genetic	2	1	2	Negative Genetic, Negative Genetic
RPS21A	YKR057W	Protein component of the small (40S) ribosomal subunit	genetic	2	1	2	Positive Genetic, Positive Genetic
SIS2	YKR072C	Negative regulatory subunit of protein phosphatase 1 (Ppz1p)	genetic	2	1	2	Positive Genetic, Positive Genetic
SND2	YLR065C	Protein involved in SRP-independent targeting of substrates to the ER	genetic	2	1	2	Negative Genetic, Negative Genetic
IOC2	YLR095C	Subunit of the Isw1b complex	genetic	2	1	2	Negative Genetic, Negative Genetic
IMH1	YLR309C	Protein involved in vesicular transport	genetic	2	1	2	Negative Genetic, Negative Genetic
CST9	YLR394W	SUMO E3 ligase	genetic	2	1	2	Negative Genetic, Negative Genetic
RPN13	YLR421C	Subunit of the 19S regulatory particle of the 26S proteasome lid	genetic	2	1	2	Negative Genetic, Negative Genetic
ERG5	YMR015C	C-22 sterol desaturase	genetic	2	1	2	Negative Genetic, Negative Genetic
UBC7	YMR022W	Ubiquitin conjugating enzyme	genetic	2	1	2	Positive Genetic, Positive Genetic
SAM37	YMR060C	Component of the Sorting and Assembly Machinery (SAM) complex	genetic	2	1	2	Negative Genetic, Negative Genetic
CUE1	YMR264W	Ubiquitin-binding protein	genetic	2	1	2	Positive Genetic, Positive Genetic
FAR11	YNL127W	Protein involved in recovery from cell cycle arrest	genetic	2	1	2	Negative Genetic, Negative Genetic
OCA1	YNL099C	Putative protein tyrosine phosphatase	genetic	2	1	2	Negative Genetic, Negative Genetic
EOS1	YNL080C	Protein involved in N-glycosylation	genetic	2	1	2	Negative Genetic, Negative Genetic
CKB2	YOR039W	Beta' regulatory subunit of casein kinase 2 (CK2)	genetic	2	1	2	Positive Genetic, Positive Genetic
IDH2	YOR136W	Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase	genetic	2	1	2	Negative Genetic, Negative Genetic
RPS28A	YOR167C	Protein component of the small (40S) ribosomal subunit	genetic	2	1	2	Positive Genetic, Positive Genetic
LTE1	YAL024C	Protein similar to GDP/GTP exchange factors	genetic	2	1	2	Negative Genetic, Negative Genetic
RXT2	YBR095C	Component of the histone deacetylase Rpd3L complex	genetic	2	1	2	Negative Genetic, Negative Genetic
RUB1	YDR139C	Ubiquitin-like protein with similarity to mammalian NEDD8	genetic	2	1	2	Negative Genetic, Negative Genetic
XRN1	YGL173C	Evolutionarily-conserved 5'-3' exonuclease	genetic	2	1	2	Negative Genetic, Negative Genetic
SDH1	YKL148C	Flavoprotein subunit of succinate dehydrogenase	genetic	2	1	2	Negative Genetic, Negative Genetic
UBC12	YLR306W	Enzyme that mediates the conjugation of Rub1p	genetic	2	1	2	Negative Genetic, Negative Genetic
NUP2	YLR335W	Nucleoporin involved in nucleocytoplasmic transport	genetic	2	1	2	Negative Genetic, Negative Genetic
TRM11	YOL124C	Catalytic subunit of adoMet-dependent tRNA methyltransferase complex	genetic	2	1	2	Negative Genetic, Negative Genetic
ULA1	YPL003W	Protein that activates Rub1p (NEDD8) before neddylation	genetic	2	1	2	Negative Genetic, Negative Genetic
QCR2	YPR191W	Subunit 2 of ubiquinol cytochrome-c reductase (Complex III)	genetic	2	1	2	Negative Genetic, Negative Genetic
RAD61	YDR014W	Subunit of a complex that inhibits sister chromatid cohesion	genetic	2	1	2	Dosage Rescue, Dosage Rescue
CBC2	YPL178W	Small subunit of the heterodimeric cap binding complex with Sto1p	genetic	2	1	2	Negative Genetic, Negative Genetic
ASF1	YJL115W	Nucleosome assembly factor	genetic	2	1	2	Negative Genetic, Negative Genetic
BNI1	YNL271C	Formin	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
ATG3	YNR007C	E2-like enzyme	genetic	2	1	2	Negative Genetic, Negative Genetic
CAF20	YOR276W	Phosphoprotein of the mRNA cap-binding complex	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
BTS1	YPL069C	Geranylgeranyl diphosphate synthase (GGPPS)	genetic	2	1	2	Positive Genetic, Positive Genetic
IRC20	YLR247C	E3 ubiquitin ligase and putative helicase	physical	2	2	1	Affinity Capture-MS, Affinity Capture-Western
EST1	YLR233C	TLC1 RNA-associated factor involved in telomere length regulation	physical	2	2	1	Affinity Capture-Western, Affinity Capture-MS
DDI1	YER143W	Aspartic-type endopeptidase	physical	2	2	1	Affinity Capture-MS, Affinity Capture-Western
SNU114	YKL173W	GTPase component of U5 snRNP involved in mRNA splicing via spliceosome	genetic	2	2	1	Positive Genetic, Negative Genetic
DBP6	YNR038W	Essential protein involved in ribosome biogenesis	genetic	2	2	1	Positive Genetic, Negative Genetic
LAS17	YOR181W	Actin assembly factor	genetic	2	2	1	Positive Genetic, Negative Genetic
PTI1	YGR156W	Essential component of CPF (cleavage and polyadenylation factor)	genetic	2	2	1	Positive Genetic, Negative Genetic
YHC1	YLR298C	Component of the U1 snRNP complex required for pre-mRNA splicing	genetic	2	2	1	Positive Genetic, Negative Genetic
PBR1	YNL181W	Putative oxidoreductase	genetic	2	2	1	Positive Genetic, Negative Genetic
YKL069W	YKL069W	Methionine-R-sulfoxide reductase	genetic	2	2	1	Positive Genetic, Negative Genetic
RPL9B	YNL067W	Ribosomal 60S subunit protein L9B	genetic	2	2	1	Positive Genetic, Negative Genetic
GPI10	YGL142C	Integral membrane protein involved in GPI anchor synthesis	genetic	2	2	1	Phenotypic Suppression, Dosage Rescue
HRQ1	YDR291W	3'-5' DNA helicase of the conserved RecQ family	genetic	2	2	1	Positive Genetic, Negative Genetic
SAN1	YDR143C	Ubiquitin-protein ligase	genetic	2	2	1	Synthetic Rescue, Phenotypic Suppression
UBR1	YGR184C	E3 ubiquitin ligase (N-recognin)	genetic	2	2	1	Synthetic Rescue, Phenotypic Suppression
BUD20	YLR074C	C2H2-type zinc finger protein required for ribosome assembly	genetic	2	2	1	Positive Genetic, Negative Genetic
BRR1	YPR057W	snRNP protein component of spliceosomal snRNPs	genetic	2	2	1	Positive Genetic, Negative Genetic
BRL1	YHR036W	Essential nuclear envelope/ER integral membrane protein	genetic	2	2	1	Positive Genetic, Negative Genetic
FAR1	YJL157C	CDK inhibitor and nuclear anchor	physical	2	1	1	Affinity Capture-Western, Affinity Capture-Western
SMT3	YDR510W	Ubiquitin-like protein of the SUMO family	genetic	2	1	1	Negative Genetic, Negative Genetic
RPT1	YKL145W	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
RPN11	YFR004W	Metalloprotease subunit of 19S regulatory particle	genetic	2	1	1	Negative Genetic, Negative Genetic
YTA7	YGR270W	Chromatin-binding ATPase that regulates histone gene expression	genetic	2	1	1	Negative Genetic, Negative Genetic
RAD52	YML032C	Protein involved in homologous recombination	physical	2	1	1	Affinity Capture-Western, Affinity Capture-Western
DCP2	YNL118C	Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC24	YIL109C	Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat	genetic	2	1	1	Negative Genetic, Negative Genetic
HSH155	YMR288W	U2-snRNP associated splicing factor	physical	2	1	1	Affinity Capture-Western, Affinity Capture-Western
COG3	YER157W	Essential component of the conserved oligomeric Golgi complex	genetic	2	1	1	Positive Genetic, Positive Genetic
ORC3	YLL004W	Subunit of the origin recognition complex (ORC)	genetic	2	1	1	Positive Genetic, Positive Genetic
SEC27	YGL137W	Essential beta'-coat protein of the COPI coatomer	genetic	2	1	1	Positive Genetic, Positive Genetic
NAP1	YKR048C	Histone chaperone and assembly chaperone for Rps6a/b	genetic	2	1	1	Positive Genetic, Positive Genetic
MUB1	YMR100W	MYND domain-containing protein	genetic	2	1	1	Positive Genetic, Positive Genetic
PRE7	YBL041W	Beta 6 subunit of the 20S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
CMD1	YBR109C	Calmodulin	genetic	2	1	1	Negative Genetic, Negative Genetic
CKS1	YBR135W	Cyclin-dependent protein kinase regulatory subunit and adaptor	genetic	2	1	1	Negative Genetic, Negative Genetic
NSE3	YDR288W	Component of the SMC5-SMC6 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC20	YDR498C	Membrane glycoprotein v-SNARE	genetic	2	1	1	Negative Genetic, Negative Genetic
MOB2	YFL034C-B	Activator of Cbk1p kinase	genetic	2	1	1	Negative Genetic, Negative Genetic
HSF1	YGL073W	Trimeric heat shock transcription factor	genetic	2	1	1	Negative Genetic, Negative Genetic
DNA2	YHR164C	ATP-dependent 5'-flap endonuclease and DNA helicase	genetic	2	1	1	Negative Genetic, Negative Genetic
CTF8	YHR191C	Subunit of a complex with Ctf18p	genetic	2	1	1	Negative Genetic, Negative Genetic
MCM10	YIL150C	Essential chromatin-associated protein	genetic	2	1	1	Negative Genetic, Negative Genetic
PAM16	YJL104W	Subunit of the import motor (PAM complex)	genetic	2	1	1	Negative Genetic, Negative Genetic
NSE1	YLR007W	Component of the SMC5-SMC6 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC22	YLR268W	R-SNARE protein	genetic	2	1	1	Negative Genetic, Negative Genetic
NSE5	YML023C	Component of the SMC5-SMC6 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC65	YML105C	Subunit of the signal recognition particle (SRP)	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC12	YNR026C	Guanine nucleotide exchange factor (GEF)	genetic	2	1	1	Negative Genetic, Negative Genetic
TPT1	YOL102C	tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing	genetic	2	1	1	Negative Genetic, Negative Genetic
PRE10	YOR362C	Alpha 7 subunit of the 20S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
ULP1	YPL020C	Protease that specifically cleaves Smt3p protein conjugates	genetic	2	1	1	Negative Genetic, Negative Genetic
RPN7	YPR108W	Essential non-ATPase regulatory subunit of the 26S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
NUP57	YGR119C	FG-nucleoporin component of central core of the nuclear pore complex	genetic	2	1	1	Negative Genetic, Negative Genetic
ERG11	YHR007C	Lanosterol 14-alpha-demethylase	genetic	2	1	1	Negative Genetic, Negative Genetic
NMT1	YLR195C	N-myristoyl transferase	genetic	2	1	1	Negative Genetic, Negative Genetic
KAP95	YLR347C	Karyopherin beta	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC62	YPL094C	Essential subunit of Sec63 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
PUP3	YER094C	Beta 3 subunit of the 20S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
SCL1	YGL011C	Alpha 1 subunit of the 20S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
RPN1	YHR027C	Non-ATPase base subunit of the 19S RP of the 26S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
PRE6	YOL038W	Alpha 4 subunit of the 20S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
PUP1	YOR157C	Beta 2 subunit of the 20S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
TFC8	YPL007C	Subunit of RNA polymerase III transcription initiation factor complex	genetic	2	1	1	Negative Genetic, Negative Genetic
PRE2	YPR103W	Beta 5 subunit of the 20S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
DEP1	YAL013W	Component of the Rpd3L histone deacetylase complex	genetic	2	1	1	Negative Genetic, Negative Genetic
DCC1	YCL016C	Subunit of a complex with Ctf8p and Ctf18p	genetic	2	1	1	Negative Genetic, Negative Genetic
IPK1	YDR315C	Inositol 1,3,4,5,6-pentakisphosphate 2-kinase	genetic	2	1	1	Negative Genetic, Negative Genetic
GCN20	YFR009W	Positive regulator of the Gcn2p kinase activity	genetic	2	1	1	Negative Genetic, Negative Genetic
ICE2	YIL090W	Integral ER membrane protein with type-III transmembrane domains	genetic	2	1	1	Negative Genetic, Negative Genetic
PHO86	YJL117W	Endoplasmic reticulum (ER) resident protein	genetic	2	1	1	Negative Genetic, Negative Genetic
ROY1	YMR258C	GTPase inhibitor with similarity to F-box proteins	genetic	2	1	1	Negative Genetic, Negative Genetic
PPG1	YNR032W	Serine protein phosphatase involved in formation of FAR complex	genetic	2	1	1	Negative Genetic, Negative Genetic
OST3	YOR085W	Gamma subunit of the oligosaccharyltransferase complex of the ER lumen	genetic	2	1	1	Negative Genetic, Negative Genetic
RMI1	YPL024W	Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex	genetic	2	1	1	Negative Genetic, Negative Genetic
PAU13	YHL046C	Protein of unknown function	genetic	2	1	1	Negative Genetic, Negative Genetic
PKR1	YMR123W	V-ATPase assembly factor	genetic	2	1	1	Negative Genetic, Negative Genetic
YBL086C	YBL086C	Protein of unknown function	genetic	2	1	1	Negative Genetic, Negative Genetic
RTF1	YGL244W	Subunit of RNAPII-associated chromatin remodeling Paf1 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
EMC6	YLL014W	Member of conserved ER transmembrane complex	genetic	2	1	1	Negative Genetic, Negative Genetic
ERG6	YML008C	Delta(24)-sterol C-methyltransferase	genetic	2	1	1	Negative Genetic, Negative Genetic
APC2	YLR127C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	2	1	1	Negative Genetic, Negative Genetic
BET2	YPR176C	Beta subunit of Type II geranylgeranyltransferase	genetic	2	1	1	Negative Genetic, Negative Genetic
CDC16	YKL022C	Subunit of the anaphase-promoting complex/cyclosome (APC/C)	genetic	2	1	1	Negative Genetic, Negative Genetic
CDC23	YHR166C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	2	1	1	Negative Genetic, Negative Genetic
CDC20	YGL116W	Activator of anaphase-promoting complex/cyclosome (APC/C)	genetic	2	1	1	Negative Genetic, Negative Genetic
CDC4	YFL009W	F-box protein required for both the G1/S and G2/M phase transitions	genetic	2	1	1	Negative Genetic, Negative Genetic
ASK1	YKL052C	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	2	1	1	Negative Genetic, Negative Genetic
BOS1	YLR078C	v-SNARE (vesicle specific SNAP receptor)	genetic	2	1	1	Negative Genetic, Negative Genetic
APC5	YOR249C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	2	1	1	Negative Genetic, Negative Genetic
CDC27	YBL084C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	2	1	1	Negative Genetic, Negative Genetic
ABF1	YKL112W	DNA binding protein with possible chromatin-reorganizing activity	genetic	2	1	1	Negative Genetic, Negative Genetic
BUL2	YML111W	Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex	physical	2	1	1	Affinity Capture-MS, Affinity Capture-MS
BRR6	YGL247W	Essential nuclear envelope integral membrane protein	genetic	2	1	1	Negative Genetic, Negative Genetic
SFP1	YLR403W	Regulates transcription of ribosomal protein and biogenesis genes	regulation	1	1	1	DNA to cDNA expression microarray evidence
GCN5	YGR252W	Catalytic subunit of ADA and SAGA histone acetyltransferase complexes	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
TEC1	YBR083W	Transcription factor targeting filamentation genes and Ty1 expression	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
GCR1	YPL075W	Transcriptional activator of genes involved in glycolysis	regulation	1	1	1	DNA to cDNA expression microarray evidence
MED2	YDL005C	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
RGR1	YLR071C	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SIN4	YNL236W	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	DNA to cDNA expression microarray evidence
TFC7	YOR110W	RNA pol III transcription initiation factor complex (TFIIIC) subunit	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SUA7	YPR086W	Transcription factor TFIIB	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
UGA3	YDL170W	Transcriptional activator for GABA-dependent induction of GABA genes	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ARP4	YJL081C	Nuclear actin-related protein involved in chromatin remodeling	genetic	1	1	1	Negative Genetic
BRX1	YOL077C	Nucleolar protein	genetic	1	1	1	Positive Genetic
BRR2	YER172C	RNA-dependent ATPase RNA helicase (DEIH box)	genetic	1	1	1	Negative Genetic
BMH1	YER177W	14-3-3 protein, major isoform	genetic	1	1	1	Negative Genetic
TIF4631	YGR162W	Translation initiation factor eIF4G and scaffold protein	physical	1	1	1	Affinity Capture-MS
NPL4	YBR170C	Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase	genetic	1	1	1	Synthetic Lethality
KRS1	YDR037W	Lysyl-tRNA synthetase	physical	1	1	1	Affinity Capture-MS
PAC10	YGR078C	Part of the heteromeric co-chaperone GimC/prefoldin complex	physical	1	1	1	Affinity Capture-MS
SPT23	YKL020C	ER membrane protein involved in regulation of OLE1 transcription	genetic	1	1	1	Positive Genetic
UFE1	YOR075W	t-SNARE protein required for retrograde vesicular traffic	physical	1	1	1	Affinity Capture-Western
UBI4	YLL039C	Ubiquitin	genetic	1	1	1	Dosage Rescue
FAR1	YJL157C	CDK inhibitor and nuclear anchor	genetic	1	1	1	Phenotypic Suppression
UBX2	YML013W	Bridging factor involved in ER-associated protein degradation (ERAD)	genetic	1	1	1	Negative Genetic
CDC53	YDL132W	Cullin	physical	1	1	1	Affinity Capture-MS
URB1	YKL014C	Protein required for the normal accumulation of 25S and 5.8S rRNAs	physical	1	1	1	Affinity Capture-MS
PRE1	YER012W	Beta 4 subunit of the 20S proteasome	genetic	1	1	1	Negative Genetic
UFD2	YDL190C	Ubiquitin (Ub) chain assembly factor (E4)	genetic	1	1	1	Synthetic Rescue
TUP1	YCR084C	General repressor of transcription in complex with Cyc8p	physical	1	1	1	Affinity Capture-MS
HDA2	YDR295C	Subunit of HDA1 histone deacetylase complex	physical	1	1	1	Affinity Capture-MS
HDA2	YDR295C	Subunit of HDA1 histone deacetylase complex	genetic	1	1	1	Negative Genetic
OTU1	YFL044C	Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p	genetic	1	1	1	Negative Genetic
SRB5	YGR104C	Subunit of the RNA polymerase II mediator complex	physical	1	1	1	Affinity Capture-MS
EAP1	YKL204W	eIF4E-associated protein, competes with eIF4G for binding to eIF4E	physical	1	1	1	Affinity Capture-MS
DAD2	YKR083C	Essential subunit of the Dam1 complex (aka DASH complex)	physical	1	1	1	Affinity Capture-MS
DAD2	YKR083C	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	1	1	1	Negative Genetic
HIF1	YLL022C	Non-essential component of the HAT-B histone acetyltransferase complex	physical	1	1	1	Affinity Capture-MS
FBP1	YLR377C	Fructose-1,6-bisphosphatase	physical	1	1	1	Affinity Capture-MS
TEM1	YML064C	GTPase involved in initiation of Mitotic Exit Network (MEN)	physical	1	1	1	Affinity Capture-MS
HHT2	YNL031C	Histone H3	physical	1	1	1	Affinity Capture-MS
COG6	YNL041C	Component of the conserved oligomeric Golgi complex	physical	1	1	1	Affinity Capture-MS
MED4	YOR174W	Subunit of the RNA polymerase II mediator complex	physical	1	1	1	Affinity Capture-MS
RGL1	YPL066W	Regulator of Rho1p signaling, cofactor of Tus1p	physical	1	1	1	Affinity Capture-MS
NUT2	YPR168W	Subunit of the RNA polymerase II mediator complex	physical	1	1	1	Affinity Capture-MS
NUT2	YPR168W	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
HRD1	YOL013C	Ubiquitin-protein ligase involved in ER-associated degradation (ERAD)	genetic	1	1	1	Phenotypic Enhancement
RPL8B	YLL045C	Ribosomal 60S subunit protein L8A	physical	1	1	1	Affinity Capture-MS
RPS17B	YDR447C	Ribosomal protein 51 (rp51) of the small (40s) subunit	physical	1	1	1	Affinity Capture-MS
RPS17B	YDR447C	Ribosomal protein 51 (rp51) of the small (40s) subunit	genetic	1	1	1	Positive Genetic
RPL17B	YJL177W	Ribosomal 60S subunit protein L17B	physical	1	1	1	Affinity Capture-MS
PTM1	YKL039W	Protein of unknown function	physical	1	1	1	Affinity Capture-MS
PTK2	YJR059W	Serine/threonine protein kinase	physical	1	1	1	Biochemical Activity
USA1	YML029W	Scaffold subunit of the Hrd1p ubiquitin ligase	genetic	1	1	1	Positive Genetic
YOS9	YDR057W	ER quality-control lectin	physical	1	1	1	Affinity Capture-MS
DFM1	YDR411C	Endoplasmic reticulum (ER) localized protein	genetic	1	1	1	Dosage Growth Defect
RPT1	YKL145W	ATPase of the 19S regulatory particle of the 26S proteasome	physical	1	1	1	Affinity Capture-Western
CDC5	YMR001C	Polo-like kinase required for mitotic exit	physical	1	1	1	Affinity Capture-MS
RPN10	YHR200W	Proteasome polyubiquitin receptor	physical	1	1	1	Affinity Capture-MS
RPT5	YOR117W	ATPase of the 19S regulatory particle of the 26S proteasome	physical	1	1	1	Affinity Capture-MS
RPT5	YOR117W	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	1	1	1	Negative Genetic
YTA7	YGR270W	Chromatin-binding ATPase that regulates histone gene expression	physical	1	1	1	Affinity Capture-MS
NAB2	YGL122C	Nuclear polyadenylated RNA-binding protein	physical	1	1	1	Affinity Capture-RNA
SSE2	YBR169C	Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family	physical	1	1	1	Affinity Capture-Western
MCA1	YOR197W	Ca2+-dependent cysteine protease	genetic	1	1	1	Synthetic Growth Defect
DSN1	YIR010W	Essential component of the outer kinetochore MIND complex	physical	1	1	1	Affinity Capture-MS
PMT1	YDL095W	Protein O-mannosyltransferase of the ER membrane	physical	1	1	1	Affinity Capture-MS
PMT2	YAL023C	Protein O-mannosyltransferase of the ER membrane	physical	1	1	1	Affinity Capture-MS
CSE4	YKL049C	Centromeric histone H3-like protein	physical	1	1	1	Affinity Capture-MS
GIS2	YNL255C	Translational activator for mRNAs with internal ribosome entry sites	physical	1	1	1	Affinity Capture-RNA
URN1	YPR152C	Protein of unknown function containing WW and FF domains	physical	1	1	1	Affinity Capture-MS
NPR1	YNL183C	Protein kinase	physical	1	1	1	Reconstituted Complex
ECM29	YHL030W	Scaffold protein	physical	1	1	1	Affinity Capture-MS
SPT7	YBR081C	Subunit of the SAGA transcriptional regulatory complex	physical	1	1	1	Affinity Capture-MS
GCN5	YGR252W	Catalytic subunit of ADA and SAGA histone acetyltransferase complexes	physical	1	1	1	Affinity Capture-MS
SUS1	YBR111W-A	Global transcriptional regulator, component of SAGA, TREX-2 complexes	physical	1	1	1	Affinity Capture-MS
SEC23	YPR181C	GTPase-activating protein, stimulates the GTPase activity of Sar1p	genetic	1	1	1	Negative Genetic
MMM1	YLL006W	ER integral membrane protein, ERMES complex subunit	physical	1	1	1	Affinity Capture-MS
SSB1	YDL229W	Cytoplasmic ATPase that is a ribosome-associated molecular chaperone	physical	1	1	1	Affinity Capture-MS
SSA2	YLL024C	HSP70 family ATP-binding protein	physical	1	1	1	Affinity Capture-MS
LSM1	YJL124C	Lsm (Like Sm) protein	physical	1	1	1	Affinity Capture-RNA
SBP1	YHL034C	Protein that binds eIF4G and has a role in repression of translation	physical	1	1	1	Affinity Capture-RNA
RPL18B	YNL301C	Ribosomal 60S subunit protein L18B	physical	1	1	1	Affinity Capture-Western
NNT1	YLR285W	S-adenosylmethionine-dependent methyltransferase	physical	1	1	1	Affinity Capture-MS
RAD52	YML032C	Protein involved in homologous recombination	genetic	1	1	1	Negative Genetic
UBP10	YNL186W	Ubiquitin-specific protease, deubiquitinates Ub-protein moieties	physical	1	1	1	Affinity Capture-MS
MET4	YNL103W	Leucine-zipper transcriptional activator	physical	1	1	1	Co-localization
DCP2	YNL118C	Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex	physical	1	1	1	Affinity Capture-MS
SSB2	YNL209W	Cytoplasmic ATPase that is a ribosome-associated molecular chaperone	physical	1	1	1	Co-purification
VPS30	YPL120W	Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II	physical	1	1	1	Affinity Capture-MS
VPS15	YBR097W	Serine/threonine protein kinase involved in vacuolar protein sorting	physical	1	1	1	Affinity Capture-MS
SEC13	YLR208W	Structural component of 3 complexes	physical	1	1	1	Affinity Capture-MS
SEC24	YIL109C	Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat	physical	1	1	1	Affinity Capture-MS
VPS34	YLR240W	Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate	physical	1	1	1	Affinity Capture-MS
MMS22	YLR320W	Subunit of E3 ubiquitin ligase complex involved in replication repair	physical	1	1	1	Affinity Capture-MS
RSP5	YER125W	NEDD4 family E3 ubiquitin ligase	physical	1	1	1	Affinity Capture-MS
MDM34	YGL219C	Mitochondrial component of the ERMES complex	physical	1	1	1	Affinity Capture-Western
TOM1	YDR457W	E3 ubiquitin ligase of the hect-domain class	physical	1	1	1	Affinity Capture-MS
RVB2	YPL235W	ATP-dependent DNA helicase, also known as reptin	physical	1	1	1	Affinity Capture-MS
RVB1	YDR190C	ATP-dependent DNA helicase, also known as pontin	physical	1	1	1	Affinity Capture-MS
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	genetic	1	1	1	Dosage Rescue
TMA108	YIL137C	Ribosome-associated, nascent chain binding factor	physical	1	1	1	Affinity Capture-MS
RPL16A	YIL133C	Ribosomal 60S subunit protein L16A	physical	1	1	1	Affinity Capture-MS
TMA46	YOR091W	Protein of unknown function that associates with translating ribosomes	physical	1	1	1	Affinity Capture-MS
TMA46	YOR091W	Protein of unknown function that associates with translating ribosomes	genetic	1	1	1	Negative Genetic
GCN4	YEL009C	bZIP transcriptional activator of amino acid biosynthetic genes	physical	1	1	1	Affinity Capture-Western
SUP35	YDR172W	Translation termination factor eRF3	physical	1	1	1	Affinity Capture-MS
SUP35	YDR172W	Translation termination factor eRF3	genetic	1	1	1	Positive Genetic
VID30	YGL227W	Central component of GID Complex, involved in FBPase degradation	physical	1	1	1	Affinity Capture-MS
GID7	YCL039W	Subunit of GID Complex that binds directly to central component Vid30p	physical	1	1	1	Affinity Capture-MS
VID24	YBR105C	GID Complex regulatory subunit	physical	1	1	1	Affinity Capture-MS
SAM50	YNL026W	Component of the Sorting and Assembly Machinery (SAM) complex	physical	1	1	1	Affinity Capture-MS
PSG1	YKL077W	Protein that promotes the transport and maturation of Pma1 with Exp1	physical	1	1	1	Affinity Capture-MS
SLD5	YDR489W	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p)	physical	1	1	1	Affinity Capture-Western
VAM6	YDL077C	Guanine nucleotide exchange factor for the GTPase Gtr1p	physical	1	1	1	Affinity Capture-MS
RRP6	YOR001W	Nuclear exosome exonuclease component	physical	1	1	1	Affinity Capture-MS
RRP6	YOR001W	Nuclear exosome exonuclease component	genetic	1	1	1	Positive Genetic
DEF1	YKL054C	RNAPII degradation factor	physical	1	1	1	Affinity Capture-MS
DEF1	YKL054C	RNAPII degradation factor	genetic	1	1	1	Negative Genetic
YCS4	YLR272C	Subunit of the condensin complex	physical	1	1	1	Affinity Capture-Western
MOG1	YJR074W	Conserved nuclear protein that interacts with GTP-Gsp1p	physical	1	1	1	Affinity Capture-MS
MOG1	YJR074W	Conserved nuclear protein that interacts with GTP-Gsp1p	genetic	1	1	1	Positive Genetic
DDI1	YER143W	Aspartic-type endopeptidase	genetic	1	1	1	Phenotypic Suppression
MPS3	YJL019W	Nuclear envelope protein	physical	1	1	1	Affinity Capture-MS
CLN3	YAL040C	G1 cyclin involved in cell cycle progression	physical	1	1	1	Affinity Capture-Western
FIS1	YIL065C	Protein involved in mitochondrial fission and peroxisome abundance	physical	1	1	1	Affinity Capture-MS
RET1	YOR207C	Second-largest subunit of RNA polymerase III	physical	1	1	1	Affinity Capture-MS
TFC6	YDR362C	Subunit of RNA polymerase III transcription initiation factor complex	physical	1	1	1	Affinity Capture-MS
TOM40	YMR203W	Component of the TOM (translocase of outer membrane) complex	physical	1	1	1	Affinity Capture-Western
SBH1	YER087C-B	Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p)	physical	1	1	1	Two-hybrid
HSC82	YMR186W	Cytoplasmic chaperone of the Hsp90 family	physical	1	1	1	Affinity Capture-MS
PAB1	YER165W	Poly(A) binding protein	physical	1	1	1	Affinity Capture-Western
PAB1	YER165W	Poly(A) binding protein	genetic	1	1	1	Dosage Rescue
UBC6	YER100W	Ubiquitin-conjugating enzyme involved in ERAD	physical	1	1	1	Reconstituted Complex
UBC6	YER100W	Ubiquitin-conjugating enzyme involved in ERAD	genetic	1	1	1	Positive Genetic
SMC6	YLR383W	Subunit of the SMC5-SMC6 complex	physical	1	1	1	Affinity Capture-MS
ULP2	YIL031W	Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins	physical	1	1	1	Two-hybrid
MCM7	YBR202W	Component of the Mcm2-7 hexameric helicase complex	physical	1	1	1	Affinity Capture-Western
SIS1	YNL007C	Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p	physical	1	1	1	Affinity Capture-MS
RPS0A	YGR214W	Ribosomal 40S subunit protein S0A	physical	1	1	1	Affinity Capture-MS
RPS0A	YGR214W	Ribosomal 40S subunit protein S0A	genetic	1	1	1	Positive Genetic
RPS1A	YLR441C	Ribosomal protein of the small (40S) subunit	physical	1	1	1	Affinity Capture-MS
RPS6A	YPL090C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS6A	YPL090C	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
RPS7A	YOR096W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS8A	YBL072C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS9A	YPL081W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS10A	YOR293W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS12	YOR369C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS13	YDR064W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS15	YOL040C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS17A	YML024W	Ribosomal protein 51 (rp51) of the small (40s) subunit	physical	1	1	1	Affinity Capture-MS
RPS18A	YDR450W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS19A	YOL121C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS20	YHL015W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS22A	YJL190C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPL25	YOL127W	Ribosomal 60S subunit protein L25	physical	1	1	1	Affinity Capture-MS
RPL26A	YLR344W	Ribosomal 60S subunit protein L26A	physical	1	1	1	Affinity Capture-MS
RPS27A	YKL156W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPL31A	YDL075W	Ribosomal 60S subunit protein L31A	physical	1	1	1	Affinity Capture-MS
RPS3	YNL178W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
RPS14A	YCR031C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
MTQ2	YDR140W	S-adenosylmethionine-dependent methyltransferase	physical	1	1	1	Affinity Capture-MS
LRS4	YDR439W	Nucleolar protein that forms a complex with Csm1p	physical	1	1	1	Affinity Capture-Western
NUR1	YDL089W	Protein involved in regulation of mitotic exit	physical	1	1	1	Affinity Capture-Western
EPS1	YIL005W	ER protein with chaperone and co-chaperone activity	genetic	1	1	1	Synthetic Growth Defect
OCA6	YDR067C	Cytoplasmic protein required for replication of Brome mosaic virus	genetic	1	1	1	Negative Genetic
UBC13	YDR092W	E2 ubiquitin-conjugating enzyme	genetic	1	1	1	Negative Genetic
RPA14	YDR156W	RNA polymerase I subunit A14	genetic	1	1	1	Positive Genetic
MET32	YDR253C	Zinc-finger DNA-binding transcription factor	genetic	1	1	1	Negative Genetic
VPS60	YDR486C	Protein involved in late endosome to vacuole transport	genetic	1	1	1	Positive Genetic
KRE28	YDR532C	Subunit of a kinetochore-microtubule binding complex	genetic	1	1	1	Positive Genetic
YCK3	YER123W	Palmitoylated vacuolar membrane-localized casein kinase I isoform	genetic	1	1	1	Negative Genetic
YHB1	YGR234W	Nitric oxide oxidoreductase	genetic	1	1	1	Negative Genetic
SOP4	YJL192C	ER-membrane protein	genetic	1	1	1	Negative Genetic
PIR5	YJL160C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
MUD2	YKL074C	Protein involved in early pre-mRNA splicing	genetic	1	1	1	Positive Genetic
SRL2	YLR082C	Protein of unknown function	genetic	1	1	1	Negative Genetic
MSC3	YLR219W	Protein of unknown function	genetic	1	1	1	Negative Genetic
CMG1	YLR271W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
YGK3	YOL128C	Protein kinase related to mammalian GSK-3 glycogen synthase kinases	genetic	1	1	1	Negative Genetic
SKM1	YOL113W	Member of the PAK family of serine/threonine protein kinases	genetic	1	1	1	Negative Genetic
INO4	YOL108C	Transcription factor involved in phospholipid synthesis	genetic	1	1	1	Negative Genetic
SDH8	YBR269C	Protein required for assembly of succinate dehydrogenase	genetic	1	1	1	Negative Genetic
SSD1	YDR293C	Translational repressor	genetic	1	1	1	Negative Genetic
RPS21B	YJL136C	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
GZF3	YJL110C	GATA zinc finger protein	genetic	1	1	1	Negative Genetic
SIC1	YLR079W	Cyclin-dependent kinase inhibitor (CKI)	genetic	1	1	1	Positive Genetic
VAC14	YLR386W	Enzyme regulator	genetic	1	1	1	Negative Genetic
FMP27	YLR454W	Protein with structural similarity to lipid transport protein Vps13p	genetic	1	1	1	Negative Genetic
SRC1	YML034W	Inner nuclear membrane protein	genetic	1	1	1	Negative Genetic
RIM20	YOR275C	Protein involved in proteolytic activation of Rim101p	genetic	1	1	1	Positive Genetic
MNE1	YOR350C	Protein involved in splicing Group I aI5-beta intron from COX1 mRNA	genetic	1	1	1	Negative Genetic
CHL1	YPL008W	Probable DNA helicase	genetic	1	1	1	Negative Genetic
SLY1	YDR189W	Hydrophilic protein involved in ER/Golgi vesicle trafficking	genetic	1	1	1	Phenotypic Suppression
MAD2	YJL030W	Component of the spindle-assembly checkpoint complex	genetic	1	1	1	Phenotypic Enhancement
CLN1	YMR199W	G1 cyclin involved in regulation of the cell cycle	genetic	1	1	1	Phenotypic Suppression
RHO1	YPR165W	GTP-binding protein of the rho subfamily of Ras-like proteins	genetic	1	1	1	Synthetic Growth Defect
SLT2	YHR030C	Serine/threonine MAP kinase	genetic	1	1	1	Synthetic Growth Defect
ROM2	YLR371W	Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p	genetic	1	1	1	Synthetic Growth Defect
FHL1	YPR104C	Regulator of ribosomal protein (RP) transcription	genetic	1	1	1	Dosage Rescue
RPL17A	YKL180W	Ribosomal 60S subunit protein L17A	genetic	1	1	1	Dosage Rescue
EMI1	YDR512C	Non-essential protein of unknown function	genetic	1	1	1	Dosage Rescue
HEL2	YDR266C	RING finger ubiquitin ligase (E3)	genetic	1	1	1	Dosage Rescue
SNA3	YJL151C	Protein involved in efficient MVB sorting of proteins to the vacuole	genetic	1	1	1	Dosage Rescue
TMA20	YER007C-A	Protein of unknown function that associates with ribosomes	genetic	1	1	1	Dosage Rescue
UBP1	YDL122W	Ubiquitin-specific protease	genetic	1	1	1	Dosage Rescue
PSP1	YDR505C	Asn and gln rich protein of unknown function	genetic	1	1	1	Dosage Rescue
NOP58	YOR310C	Protein involved in producing mature rRNAs and snoRNAs	genetic	1	1	1	Dosage Rescue
NOP1	YDL014W	Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus	genetic	1	1	1	Dosage Rescue
LSM8	YJR022W	Lsm (Like Sm) protein	genetic	1	1	1	Dosage Rescue
SMY2	YBR172C	GYF domain protein	genetic	1	1	1	Dosage Rescue
TAL1	YLR354C	Transaldolase, enzyme in the non-oxidative pentose phosphate pathway	genetic	1	1	1	Dosage Rescue
GYP6	YJL044C	GTPase-activating protein (GAP) for yeast Rab family member Ypt6p	genetic	1	1	1	Dosage Rescue
YRB2	YIL063C	Protein of unknown function	genetic	1	1	1	Dosage Rescue
RPL32	YBL092W	Ribosomal 60S subunit protein L32	genetic	1	1	1	Dosage Rescue
YME1	YPR024W	Catalytic subunit of i-AAA protease complex	genetic	1	1	1	Positive Genetic
TTI1	YKL033W	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	1	1	1	Positive Genetic
TTI2	YJR136C	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	1	1	1	Positive Genetic
DOA4	YDR069C	Ubiquitin hydrolase	genetic	1	1	1	Synthetic Lethality
TDP1	YBR223C	Tyrosyl-DNA phosphodiesterase I	genetic	1	1	1	Synthetic Growth Defect
TFC3	YAL001C	Subunit of RNA polymerase III transcription initiation factor complex	genetic	1	1	1	Positive Genetic
RFT1	YBL020W	Membrane protein required for translocation of Man5GlcNac2-PP-Dol	genetic	1	1	1	Positive Genetic
STU1	YBL034C	Microtubule plus-end-tracking non-motor protein	genetic	1	1	1	Positive Genetic
NFS1	YCL017C	Cysteine desulfurase involved in iron-sulfur cluster biogenesis	genetic	1	1	1	Positive Genetic
PBN1	YCL052C	Component of glycosylphosphatidylinositol-mannosyltransferase I	genetic	1	1	1	Positive Genetic
KRR1	YCL059C	Nucleolar protein required for rRNA synthesis and ribosomal assembly	genetic	1	1	1	Positive Genetic
NUP192	YJL039C	Essential subunit of inner ring of nuclear pore complex (NPC)	genetic	1	1	1	Positive Genetic
SWC4	YGR002C	Component of the Swr1p complex that incorporates Htz1p into chromatin	genetic	1	1	1	Positive Genetic
RFC2	YJR068W	Subunit of heteropentameric Replication factor C (RF-C)	genetic	1	1	1	Positive Genetic
CLF1	YLR117C	Member of the NineTeen Complex (NTC)	genetic	1	1	1	Positive Genetic
NOP56	YLR197W	Essential evolutionarily-conserved nucleolar protein	genetic	1	1	1	Positive Genetic
GPI12	YMR281W	ER membrane protein involved in the second step of GPI anchor assembly	genetic	1	1	1	Positive Genetic
TRS23	YDR246W	Core component of transport protein particle (TRAPP) complexes I-III	genetic	1	1	1	Positive Genetic
TFB1	YDR311W	Subunit of TFIIH and nucleotide excision repair factor 3 complexes	genetic	1	1	1	Positive Genetic
GWT1	YJL091C	Protein involved in the inositol acylation of GlcN-PI	genetic	1	1	1	Positive Genetic
ERG27	YLR100W	3-keto sterol reductase	genetic	1	1	1	Positive Genetic
SEC61	YLR378C	Conserved ER protein translocation channel	genetic	1	1	1	Positive Genetic
RAT1	YOR048C	Nuclear 5' to 3' single-stranded RNA exonuclease	genetic	1	1	1	Positive Genetic
DED1	YOR204W	ATP-dependent DEAD-box RNA helicase with strand-annealing activity	genetic	1	1	1	Positive Genetic
MOT1	YPL082C	Essential protein involved in regulation of transcription	genetic	1	1	1	Positive Genetic
POL12	YBL035C	B subunit of DNA polymerase alpha-primase complex	genetic	1	1	1	Positive Genetic
TAF5	YBR198C	Subunit (90 kDa) of TFIID and SAGA complexes	genetic	1	1	1	Positive Genetic
GPI11	YDR302W	ER membrane protein involved in a late step of GPI anchor assembly	genetic	1	1	1	Positive Genetic
SYF1	YDR416W	Member of the NineTeen Complex (NTC)	genetic	1	1	1	Positive Genetic
SLD3	YGL113W	Protein involved in the initiation of DNA replication	genetic	1	1	1	Positive Genetic
PRP43	YGL120C	RNA helicase in the DEAH-box family	genetic	1	1	1	Positive Genetic
SKI6	YGR195W	Exosome non-catalytic core component	genetic	1	1	1	Positive Genetic
ORC6	YHR118C	Subunit of the origin recognition complex (ORC)	genetic	1	1	1	Positive Genetic
CIA2	YHR122W	Component of cytosolic iron-sulfur protein assembly (CIA) machinery	genetic	1	1	1	Positive Genetic
UTP9	YHR196W	Nucleolar protein	genetic	1	1	1	Positive Genetic
SMC3	YJL074C	Subunit of the multiprotein cohesin complex	genetic	1	1	1	Positive Genetic
FIP1	YJR093C	Subunit of cleavage polyadenylation factor (CPF)	genetic	1	1	1	Positive Genetic
RPF2	YKR081C	Essential protein involved in rRNA maturation and ribosomal assembly	genetic	1	1	1	Positive Genetic
SDO1	YLR022C	Guanine nucleotide exchange factor (GEF) for Ria1p	genetic	1	1	1	Positive Genetic
RGR1	YLR071C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Positive Genetic
PWP1	YLR196W	Protein with WD-40 repeats involved in rRNA processing	genetic	1	1	1	Positive Genetic
DBP9	YLR276C	DEAD-box protein required for 27S rRNA processing	genetic	1	1	1	Positive Genetic
GCD7	YLR291C	Beta subunit of translation initiation factor eIF2B	genetic	1	1	1	Positive Genetic
ERB1	YMR049C	Constituent of 66S pre-ribosomal particles	genetic	1	1	1	Positive Genetic
NOP2	YNL061W	rRNA m5C methyltransferase	genetic	1	1	1	Positive Genetic
PRP2	YNR011C	RNA-dependent DExD/H-box ATPase	genetic	1	1	1	Positive Genetic
OST2	YOR103C	Epsilon subunit of the oligosaccharyltransferase complex	genetic	1	1	1	Positive Genetic
RRS1	YOR294W	Essential protein that binds ribosomal protein L11	genetic	1	1	1	Positive Genetic
TBF1	YPL128C	Telobox-containing general regulatory factor	genetic	1	1	1	Positive Genetic
MEX67	YPL169C	Poly(A)RNA binding protein involved in nuclear mRNA export	genetic	1	1	1	Positive Genetic
HRR25	YPL204W	Conserved casein kinase, monopolin subunit	genetic	1	1	1	Positive Genetic
SGV1	YPR161C	Cyclin (Bur2p)-dependent protein kinase	genetic	1	1	1	Positive Genetic
TAF10	YDR167W	Subunit (145 kDa) of TFIID and SAGA complexes	genetic	1	1	1	Positive Genetic
YCG1	YDR325W	Subunit of the condensin complex	genetic	1	1	1	Positive Genetic
GPI8	YDR331W	Catalytic subunit of the ER membrane GPI transamidase complex	genetic	1	1	1	Positive Genetic
SPP41	YDR464W	Protein of unknown function	genetic	1	1	1	Positive Genetic
PRP22	YER013W	DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase	genetic	1	1	1	Positive Genetic
GCD11	YER025W	Gamma subunit of the translation initiation factor eIF2	genetic	1	1	1	Positive Genetic
SPB4	YFL002C	Putative ATP-dependent RNA helicase	genetic	1	1	1	Positive Genetic
MCM6	YGL201C	Protein involved in DNA replication	genetic	1	1	1	Positive Genetic
TUB2	YFL037W	Beta-tubulin	genetic	1	1	1	Positive Genetic
FCF2	YLR051C	Nucleolar protein involved in the early steps of 35S rRNA processing	genetic	1	1	1	Positive Genetic
UTP13	YLR222C	Nucleolar protein	genetic	1	1	1	Positive Genetic
GPN3	YLR243W	Putative GTPase with a role in biogenesis of RNA pol II and polIII	genetic	1	1	1	Positive Genetic
THI80	YOR143C	Thiamine pyrophosphokinase	genetic	1	1	1	Positive Genetic
ESA1	YOR244W	Catalytic subunit of the histone acetyltransferase complex (NuA4)	genetic	1	1	1	Positive Genetic
GPN2	YOR262W	Putative GTPase with a specific role in RNA pol II and polIII biogenes	genetic	1	1	1	Positive Genetic
RPA190	YOR341W	RNA polymerase I largest subunit A190	genetic	1	1	1	Positive Genetic
NOG1	YPL093W	Putative GTPase	genetic	1	1	1	Positive Genetic
CET1	YPL228W	RNA 5'-triphosphatase involved in mRNA 5' capping	genetic	1	1	1	Positive Genetic
COG4	YPR105C	Essential component of the conserved oligomeric Golgi complex	genetic	1	1	1	Positive Genetic
MRD1	YPR112C	Essential conserved small ribosomal subunit (40s) synthesis factor	genetic	1	1	1	Positive Genetic
VPS8	YAL002W	Membrane-binding component of the CORVET complex	genetic	1	1	1	Positive Genetic
SCT1	YBL011W	Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase	genetic	1	1	1	Positive Genetic
YMC2	YBR104W	Putative mitochondrial inner membrane transporter	genetic	1	1	1	Positive Genetic
RPS26B	YER131W	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Positive Genetic
CKB1	YGL019W	Beta regulatory subunit of casein kinase 2 (CK2)	genetic	1	1	1	Positive Genetic
GET1	YGL020C	Subunit of the GET complex	genetic	1	1	1	Positive Genetic
SGF73	YGL066W	Subunit of DUBm module of SAGA and SLIK	genetic	1	1	1	Positive Genetic
UPF3	YGR072W	Component of the nonsense-mediated mRNA decay (NMD) pathway	genetic	1	1	1	Positive Genetic
RPS23A	YGR118W	Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit	genetic	1	1	1	Positive Genetic
PUT2	YHR037W	Delta-1-pyrroline-5-carboxylate dehydrogenase	genetic	1	1	1	Positive Genetic
EPT1	YHR123W	sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase	genetic	1	1	1	Positive Genetic
URM1	YIL008W	Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs	genetic	1	1	1	Positive Genetic
IST3	YIR005W	Component of the U2 snRNP	genetic	1	1	1	Positive Genetic
KHA1	YJL094C	Putative K+/H+ antiporter	genetic	1	1	1	Positive Genetic
RPA34	YJL148W	RNA polymerase I subunit A34.5	genetic	1	1	1	Positive Genetic
MNN11	YJL183W	Subunit of a Golgi mannosyltransferase complex	genetic	1	1	1	Positive Genetic
MDM35	YKL053C-A	Mitochondrial intermembrane space protein	genetic	1	1	1	Positive Genetic
SAM1	YLR180W	S-adenosylmethionine synthetase	genetic	1	1	1	Positive Genetic
ECM38	YLR299W	Gamma-glutamyltranspeptidase	genetic	1	1	1	Positive Genetic
SEI1	YLR404W	Seipin involved in lipid droplet (LD) assembly	genetic	1	1	1	Positive Genetic
NAM7	YMR080C	ATP-dependent RNA helicase of the SFI superfamily	genetic	1	1	1	Positive Genetic
REC114	YMR133W	Protein involved in early stages of meiotic recombination	genetic	1	1	1	Positive Genetic
YAF9	YNL107W	Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes	genetic	1	1	1	Positive Genetic
FPR1	YNL135C	Peptidyl-prolyl cis-trans isomerase (PPIase)	genetic	1	1	1	Positive Genetic
RPP2A	YOL039W	Ribosomal protein P2 alpha	genetic	1	1	1	Positive Genetic
NGL1	YOL042W	Putative endonuclease	genetic	1	1	1	Positive Genetic
DUF1	YOL087C	Ubiquitin-binding protein of unknown function	genetic	1	1	1	Positive Genetic
LPX1	YOR084W	Peroxisomal matrix-localized lipase	genetic	1	1	1	Positive Genetic
MAK3	YPR051W	Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT)	genetic	1	1	1	Positive Genetic
DST1	YGL043W	General transcription elongation factor TFIIS	genetic	1	1	1	Positive Genetic
SLA1	YBL007C	Cytoskeletal protein binding protein	genetic	1	1	1	Positive Genetic
URA7	YBL039C	Major CTP synthase isozyme (see also URA8)	genetic	1	1	1	Positive Genetic
SEA4	YBL104C	Subunit of SEACAT, a subcomplex of the SEA complex	genetic	1	1	1	Positive Genetic
RPL4A	YBR031W	Ribosomal 60S subunit protein L4A	genetic	1	1	1	Positive Genetic
RPS11B	YBR048W	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Positive Genetic
UBC4	YBR082C	Ubiquitin-conjugating enzyme (E2)	genetic	1	1	1	Positive Genetic
RPL27B	YDR471W	Ribosomal 60S subunit protein L27B	genetic	1	1	1	Positive Genetic
PKH1	YDR490C	Serine/threonine protein kinase	genetic	1	1	1	Positive Genetic
RPL2A	YFR031C-A	Ribosomal 60S subunit protein L2A	genetic	1	1	1	Positive Genetic
HXK2	YGL253W	Hexokinase isoenzyme 2	genetic	1	1	1	Positive Genetic
SLX9	YGR081C	Protein required for pre-rRNA processing	genetic	1	1	1	Positive Genetic
NEM1	YHR004C	Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme	genetic	1	1	1	Positive Genetic
SRN2	YLR119W	Component of the ESCRT-I complex	genetic	1	1	1	Positive Genetic
RFX1	YLR176C	Major transcriptional repressor of DNA-damage-regulated genes	genetic	1	1	1	Positive Genetic
SAS2	YMR127C	Histone acetyltransferase (HAT) catalytic subunit of the SAS complex	genetic	1	1	1	Positive Genetic
RKR1	YMR247C	RING domain E3 ubiquitin ligase	genetic	1	1	1	Positive Genetic
RPS7B	YNL096C	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Positive Genetic
GIM3	YNL153C	Subunit of the heterohexameric cochaperone prefoldin complex	genetic	1	1	1	Positive Genetic
RTS1	YOR014W	B-type regulatory subunit of protein phosphatase 2A (PP2A)	genetic	1	1	1	Positive Genetic
SUR1	YPL057C	Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit	genetic	1	1	1	Positive Genetic
VMA3	YEL027W	Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase	genetic	1	1	1	Positive Genetic
VMA8	YEL051W	Subunit D of the V1 peripheral membrane domain of V-ATPase	genetic	1	1	1	Positive Genetic
GLN3	YER040W	Transcriptional activator in nitrogen catabolite repression system	genetic	1	1	1	Positive Genetic
RMR1	YGL250W	Protein required for meiotic recombination and gene conversion	genetic	1	1	1	Positive Genetic
LIH1	YJR107W	Putative lipase	genetic	1	1	1	Positive Genetic
LEO1	YOR123C	Component of the Paf1 complex	genetic	1	1	1	Positive Genetic
SNT309	YPR101W	Member of the NineTeen Complex (NTC)	genetic	1	1	1	Positive Genetic
POP5	YAL033W	Subunit of both RNase MRP and nuclear RNase P	genetic	1	1	1	Negative Genetic
RPG1	YBR079C	eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3)	genetic	1	1	1	Negative Genetic
PCF11	YDR228C	mRNA 3' end processing factor	genetic	1	1	1	Negative Genetic
FMN1	YDR236C	Riboflavin kinase, produces riboflavin monophosphate (FMN)	genetic	1	1	1	Negative Genetic
SRP101	YDR292C	Signal recognition particle (SRP) receptor alpha subunit	genetic	1	1	1	Negative Genetic
SPC110	YDR356W	Inner plaque spindle pole body (SPB) component	genetic	1	1	1	Negative Genetic
SMC1	YFL008W	Subunit of the multiprotein cohesin complex	genetic	1	1	1	Negative Genetic
NBP35	YGL091C	Essential cytoplasmic iron-sulfur cluster binding protein	genetic	1	1	1	Negative Genetic
DAM1	YGR113W	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	1	1	1	Negative Genetic
YIP1	YGR172C	Integral membrane protein	genetic	1	1	1	Negative Genetic
MOB1	YIL106W	Component of the mitotic exit network	genetic	1	1	1	Negative Genetic
RHO3	YIL118W	Non-essential small GTPase of the Rho/Rac family of Ras-like proteins	genetic	1	1	1	Negative Genetic
STS1	YIR011C	Protein required for localizing proteasomes to the nucleus	genetic	1	1	1	Negative Genetic
OST1	YJL002C	Alpha subunit of the oligosaccharyltransferase complex of the ER lumen	genetic	1	1	1	Negative Genetic
KAR2	YJL034W	ATPase involved in protein import into the ER	genetic	1	1	1	Negative Genetic
KRE9	YJL174W	Glycoprotein involved in cell wall beta-glucan assembly	genetic	1	1	1	Negative Genetic
SEC39	YLR440C	Component of the Dsl1p tethering complex	genetic	1	1	1	Negative Genetic
NAB3	YPL190C	RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p)	genetic	1	1	1	Negative Genetic
POB3	YML069W	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p)	genetic	1	1	1	Negative Genetic
ERO1	YML130C	Thiol oxidase required for oxidative protein folding in the ER	genetic	1	1	1	Negative Genetic
ROT1	YMR200W	Molecular chaperone involved in protein folding in ER	genetic	1	1	1	Negative Genetic
ERG8	YMR220W	Phosphomevalonate kinase	genetic	1	1	1	Negative Genetic
TAF7	YMR227C	TFIID subunit (67 kDa)	genetic	1	1	1	Negative Genetic
RNT1	YMR239C	Nuclear dsRNA-specific ribonuclease (RNase III)	genetic	1	1	1	Negative Genetic
RPC34	YNR003C	RNA polymerase III subunit C34	genetic	1	1	1	Negative Genetic
CLP1	YOR250C	Component of the cleavage and polyadenylation factor I (CF I)	genetic	1	1	1	Negative Genetic
SEC16	YPL085W	COPII vesicle coat protein required for ER transport vesicle budding	genetic	1	1	1	Negative Genetic
NSL1	YPL233W	Essential component of the MIND kinetochore complex	genetic	1	1	1	Negative Genetic
SRP54	YPR088C	Signal recognition particle (SRP) subunit (homolog of mammalian SRP54)	genetic	1	1	1	Negative Genetic
SPN1	YPR133C	Protein involved in RNA polymerase II transcription	genetic	1	1	1	Negative Genetic
RPC82	YPR190C	RNA polymerase III subunit C82	genetic	1	1	1	Negative Genetic
RFA1	YAR007C	Subunit of heterotrimeric Replication Protein A (RPA)	genetic	1	1	1	Negative Genetic
ERG26	YGL001C	C-3 sterol dehydrogenase	genetic	1	1	1	Negative Genetic
RRP4	YHR069C	Exosome non-catalytic core component	genetic	1	1	1	Negative Genetic
NUP159	YIL115C	FG-nucleoporin component of central core of the nuclear pore complex	genetic	1	1	1	Negative Genetic
PAN1	YIR006C	Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p	genetic	1	1	1	Negative Genetic
NUP85	YJR042W	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
CFT2	YLR115W	Subunit of the mRNA cleavage and polyadenlylation factor (CPF)	genetic	1	1	1	Negative Genetic
UTP15	YMR093W	Nucleolar protein	genetic	1	1	1	Negative Genetic
SRV2	YNL138W	CAP (cyclase-associated protein)	genetic	1	1	1	Negative Genetic
NUF2	YOL069W	Component of the kinetochore-associated Ndc80 complex	genetic	1	1	1	Negative Genetic
PFY1	YOR122C	Profilin	genetic	1	1	1	Negative Genetic
SEC63	YOR254C	Essential subunit of Sec63 complex	genetic	1	1	1	Negative Genetic
RPB5	YBR154C	RNA polymerase subunit ABC27	genetic	1	1	1	Negative Genetic
POP7	YBR167C	Subunit of RNase MRP, nuclear RNase P and telomerase	genetic	1	1	1	Negative Genetic
GPI19	YDR437W	Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI	genetic	1	1	1	Negative Genetic
ECO1	YFR027W	Acetyltransferase required for sister chromatid cohesion	genetic	1	1	1	Negative Genetic
RET2	YFR051C	Delta subunit of the coatomer complex (COPI)	genetic	1	1	1	Negative Genetic
GPI1	YGR216C	Membrane protein involved in the synthesis of GlcNAc-PI	genetic	1	1	1	Negative Genetic
NDC80	YIL144W	Component of the kinetochore-associated Ndc80 complex	genetic	1	1	1	Negative Genetic
SLN1	YIL147C	Transmembrane histidine phosphotransfer kinase and osmosensor	genetic	1	1	1	Negative Genetic
POL31	YJR006W	Subunit of DNA polymerase delta (polymerase III)	genetic	1	1	1	Negative Genetic
MIF2	YKL089W	Centromeric CDEIII region binding protein	genetic	1	1	1	Negative Genetic
GPI13	YLL031C	ER membrane localized phosphoryltransferase	genetic	1	1	1	Negative Genetic
PRP19	YLL036C	Splicing factor associated with the spliceosome	genetic	1	1	1	Negative Genetic
PGA3	YML125C	Putative cytochrome b5 reductase, localized to the plasma membrane	genetic	1	1	1	Negative Genetic
MCM1	YMR043W	Transcription factor	genetic	1	1	1	Negative Genetic
PDS5	YMR076C	Cohesion maintenance factor	genetic	1	1	1	Negative Genetic
CTF13	YMR094W	Subunit of the CBF3 complex	genetic	1	1	1	Negative Genetic
RIB2	YOL066C	Bifunctional DRAP deaminase tRNA:pseudouridine synthase	genetic	1	1	1	Negative Genetic
IPL1	YPL209C	Aurora kinase of chromosomal passenger complex	genetic	1	1	1	Negative Genetic
HEM12	YDR047W	Uroporphyrinogen decarboxylase	genetic	1	1	1	Negative Genetic
PDS1	YDR113C	Securin	genetic	1	1	1	Negative Genetic
MMS21	YEL019C	Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
HYP2	YEL034W	Translation elongation factor eIF-5A	genetic	1	1	1	Negative Genetic
KRE29	YER038C	Subunit of the SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
TSC11	YER093C	Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p)	genetic	1	1	1	Negative Genetic
YPI1	YFR003C	Regulatory subunit of the type I protein phosphatase (PP1) Glc7p	genetic	1	1	1	Negative Genetic
OLE1	YGL055W	Delta(9) fatty acid desaturase	genetic	1	1	1	Negative Genetic
DUO1	YGL061C	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	1	1	1	Negative Genetic
NUP145	YGL092W	Essential protein with distinct roles in two nuclear pore subcomplexes	genetic	1	1	1	Negative Genetic
SRM1	YGL097W	Nucleotide exchange factor for Gsp1p	genetic	1	1	1	Negative Genetic
TIP20	YGL145W	Peripheral membrane protein required for COPI vesicle fusion to the ER	genetic	1	1	1	Negative Genetic
PRP31	YGR091W	Splicing factor	genetic	1	1	1	Negative Genetic
PUP2	YGR253C	Alpha 5 subunit of the 20S proteasome	genetic	1	1	1	Negative Genetic
RPP1	YHR062C	Subunit of both RNase MRP and nuclear RNase P	genetic	1	1	1	Negative Genetic
CFD1	YIL003W	Highly conserved iron-sulfur cluster binding protein	genetic	1	1	1	Negative Genetic
RPB3	YIL021W	RNA polymerase II third largest subunit B44	genetic	1	1	1	Negative Genetic
UTP25	YIL091C	Nucleolar protein	genetic	1	1	1	Negative Genetic
ESS1	YJR017C	Peptidylprolyl-cis/trans-isomerase (PPIase)	genetic	1	1	1	Negative Genetic
YAE1	YJR067C	Substrate-specific adaptor protein involved in apo-Rli1p maturation	genetic	1	1	1	Negative Genetic
SWD2	YKL018W	Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex	genetic	1	1	1	Negative Genetic
SPC42	YKL042W	Central plaque component of spindle pole body (SPB)	genetic	1	1	1	Negative Genetic
RPC25	YKL144C	RNA polymerase III subunit C25	genetic	1	1	1	Negative Genetic
EBP2	YKL172W	Required for 25S rRNA maturation and 60S ribosomal subunit assembly	genetic	1	1	1	Negative Genetic
SDS22	YKL193C	Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p	genetic	1	1	1	Negative Genetic
MIA40	YKL195W	Import and assembly protein in mitochondrial intermembrane space	genetic	1	1	1	Negative Genetic
LAS1	YKR063C	Endonuclease involved in pre-rRNA processing at both ends of ITS2	genetic	1	1	1	Negative Genetic
PRP16	YKR086W	DEAH-box RNA helicase	genetic	1	1	1	Negative Genetic
DRS1	YLL008W	Nucleolar DEAD-box protein required for ribosome assembly and function	genetic	1	1	1	Negative Genetic
SEN2	YLR105C	Subunit of the tRNA splicing endonuclease	genetic	1	1	1	Negative Genetic
TUB4	YLR212C	Gamma-tubulin	genetic	1	1	1	Negative Genetic
HSP60	YLR259C	Tetradecameric mitochondrial chaperonin	genetic	1	1	1	Negative Genetic
NUP116	YMR047C	FG-nucleoporin component of central core of the nuclear pore complex	genetic	1	1	1	Negative Genetic
CUS1	YMR240C	Protein required for assembly of U2 snRNP into the spliceosome	genetic	1	1	1	Negative Genetic
TIF11	YMR260C	Translation initiation factor eIF1A	genetic	1	1	1	Negative Genetic
LST8	YNL006W	Protein required for the transport of Gap1p	genetic	1	1	1	Negative Genetic
PGA2	YNL149C	Essential protein required for maturation of Gas1p and Pho8p	genetic	1	1	1	Negative Genetic
INN1	YNL152W	Essential protein that associates with contractile actomyosin ring	genetic	1	1	1	Negative Genetic
SRP1	YNL189W	Karyopherin alpha homolog	genetic	1	1	1	Negative Genetic
RAP1	YNL216W	Essential DNA-binding transcription regulator that binds many loci	genetic	1	1	1	Negative Genetic
POP1	YNL221C	Subunit of RNase MRP, nuclear RNase P and telomerase complexes	genetic	1	1	1	Negative Genetic
SMC5	YOL034W	Subunit of the SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
RKI1	YOR095C	Ribose-5-phosphate ketol-isomerase	genetic	1	1	1	Negative Genetic
SMP3	YOR149C	Alpha 1,2-mannosyltransferase	genetic	1	1	1	Negative Genetic
RPN8	YOR261C	Essential non-ATPase regulatory subunit of the 26S proteasome	genetic	1	1	1	Negative Genetic
HEM4	YOR278W	Uroporphyrinogen III synthase	genetic	1	1	1	Negative Genetic
RAD53	YPL153C	DNA damage response kinase	genetic	1	1	1	Negative Genetic
FAS2	YPL231W	Alpha subunit of fatty acid synthetase	genetic	1	1	1	Negative Genetic
YTH1	YPR107C	Essential RNA-binding component of cleavage and polyadenylation factor	genetic	1	1	1	Negative Genetic
LOT5	YKL183W	Protein of unknown function	genetic	1	1	1	Negative Genetic
DRS2	YAL026C	Trans-golgi network aminophospholipid translocase (flippase)	genetic	1	1	1	Negative Genetic
SWD1	YAR003W	Subunit of the COMPASS (Set1C) complex	genetic	1	1	1	Negative Genetic
YAR028W	YAR028W	Putative integral membrane protein	genetic	1	1	1	Negative Genetic
NCL1	YBL024W	S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase	genetic	1	1	1	Negative Genetic
RPL19B	YBL027W	Ribosomal 60S subunit protein L19B	genetic	1	1	1	Negative Genetic
PIN4	YBL051C	Protein involved in G2/M phase progression and response to DNA damage	genetic	1	1	1	Negative Genetic
PTC3	YBL056W	Type 2C protein phosphatase (PP2C)	genetic	1	1	1	Negative Genetic
MCX1	YBR227C	Non-proteolytic ATPase of the AAA family	genetic	1	1	1	Negative Genetic
CWH43	YCR017C	GPI lipid remodelase	genetic	1	1	1	Negative Genetic
YCR050C	YCR050C	Non-essential protein of unknown function	genetic	1	1	1	Negative Genetic
GIR2	YDR152W	Highly-acidic RWD domain-containing cytoplasmic protein	genetic	1	1	1	Negative Genetic
SDH4	YDR178W	Membrane anchor subunit of succinate dehydrogenase (SDH)	genetic	1	1	1	Negative Genetic
RTT103	YDR289C	Protein involved in transcription termination by RNA polymerase II	genetic	1	1	1	Negative Genetic
SWR1	YDR334W	Swi2/Snf2-related ATPase	genetic	1	1	1	Negative Genetic
HPT1	YDR399W	Dimeric hypoxanthine-guanine phosphoribosyltransferase	genetic	1	1	1	Negative Genetic
RAD51	YER095W	Strand exchange protein	genetic	1	1	1	Negative Genetic
SPT2	YER161C	Protein involved in negative regulation of transcription	genetic	1	1	1	Negative Genetic
PDA1	YER178W	E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex	genetic	1	1	1	Negative Genetic
FAR7	YFR008W	Protein involved in recovery from pheromone-induced cell cycle arrest	genetic	1	1	1	Negative Genetic
CWH41	YGL027C	Processing alpha glucosidase I	genetic	1	1	1	Negative Genetic
MUP1	YGR055W	High affinity methionine permease	genetic	1	1	1	Negative Genetic
PPT1	YGR123C	Protein serine/threonine phosphatase	genetic	1	1	1	Negative Genetic
YAP1801	YHR161C	Protein of the AP180 family, involved in clathrin cage assembly	genetic	1	1	1	Negative Genetic
STB5	YHR178W	Transcription factor	genetic	1	1	1	Negative Genetic
MGA2	YIR033W	ER membrane protein involved in regulation of OLE1 transcription	genetic	1	1	1	Negative Genetic
CHM7	YJL049W	Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum	genetic	1	1	1	Negative Genetic
IRC8	YJL051W	Bud tip localized protein of unknown function	genetic	1	1	1	Negative Genetic
RPL14A	YKL006W	Ribosomal 60S subunit protein L14A	genetic	1	1	1	Negative Genetic
CNB1	YKL190W	Calcineurin B	genetic	1	1	1	Negative Genetic
TPO1	YLL028W	Polyamine transporter of the major facilitator superfamily	genetic	1	1	1	Negative Genetic
PSR2	YLR019W	Putative plasma membrane phosphatase	genetic	1	1	1	Negative Genetic
STM1	YLR150W	Protein required for optimal translation under nutrient stress	genetic	1	1	1	Negative Genetic
YLR177W	YLR177W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
MMR1	YLR190W	Phosphorylated protein of the mitochondrial outer membrane	genetic	1	1	1	Negative Genetic
NCW2	YLR194C	GPI-anchored protein involved in cell wall remodeling	genetic	1	1	1	Negative Genetic
DMA2	YNL116W	Ubiquitin-protein ligase (E3)	genetic	1	1	1	Negative Genetic
TOP3	YLR234W	DNA Topoisomerase III	genetic	1	1	1	Negative Genetic
FAR10	YLR238W	Protein involved in recovery from arrest in response to pheromone	genetic	1	1	1	Negative Genetic
PEX30	YLR324W	ER-resident protein involved in peroxisomal biogenesis	genetic	1	1	1	Negative Genetic
REC102	YLR329W	Protein involved in early stages of meiotic recombination	genetic	1	1	1	Negative Genetic
STP3	YLR375W	Zinc-finger protein of unknown function	genetic	1	1	1	Negative Genetic
HDA1	YNL021W	Catalytic subunit of class II HDA1 histone deacetylase complex	genetic	1	1	1	Negative Genetic
LAT1	YNL071W	Dihydrolipoamide acetyltransferase component (E2) of the PDC	genetic	1	1	1	Negative Genetic
SWS2	YNL081C	Putative mitochondrial ribosomal protein of the small subunit	genetic	1	1	1	Negative Genetic
COQ10	YOL008W	Coenzyme Q (ubiquinone) binding protein	genetic	1	1	1	Negative Genetic
YOL036W	YOL036W	Protein of unknown function	genetic	1	1	1	Negative Genetic
YOL131W	YOL131W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
TRS33	YOR115C	Core component of TRAPP complexes I, II and IV	genetic	1	1	1	Negative Genetic
ULS1	YOR191W	Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL)	genetic	1	1	1	Negative Genetic
PUS7	YOR243C	Pseudouridine synthase	genetic	1	1	1	Negative Genetic
RAX1	YOR301W	Protein involved in establishing bud site selection	genetic	1	1	1	Negative Genetic
ISW2	YOR304W	ATP-dependent DNA translocase involved in chromatin remodeling	genetic	1	1	1	Negative Genetic
MSC6	YOR354C	Multicopy suppressor of HER2 involved in mitochondrial translation	genetic	1	1	1	Negative Genetic
SGF11	YPL047W	Integral subunit of SAGA histone acetyltransferase complex	genetic	1	1	1	Negative Genetic
UME1	YPL139C	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	genetic	1	1	1	Negative Genetic
RTC6	YPL183W-A	Protein involved in translation	genetic	1	1	1	Negative Genetic
YPR084W	YPR084W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
YPR096C	YPR096C	Protein of unknown function	genetic	1	1	1	Negative Genetic
POT1	YIL160C	3-ketoacyl-CoA thiolase with broad chain length specificity	genetic	1	1	1	Negative Genetic
KAR3	YPR141C	Minus-end-directed microtubule motor	genetic	1	1	1	Negative Genetic
YPR172W	YPR172W	Protein of unknown function	genetic	1	1	1	Negative Genetic
HDA3	YPR179C	Subunit of HDA1 histone deacetylase complex	genetic	1	1	1	Negative Genetic
RVS167	YDR388W	Calmodulin-binding actin-associated protein	genetic	1	1	1	Negative Genetic
FAB1	YFR019W	1-phosphatidylinositol-3-phosphate 5-kinase	genetic	1	1	1	Negative Genetic
PMR1	YGL167C	High affinity Ca2+/Mn2+ P-type ATPase	genetic	1	1	1	Negative Genetic
HUR1	YGL168W	Protein with a role in DNA repair	genetic	1	1	1	Negative Genetic
VMA21	YGR105W	Integral membrane protein required for V-ATPase function	genetic	1	1	1	Negative Genetic
PHB2	YGR231C	Subunit of the prohibitin complex (Phb1p-Phb2p)	genetic	1	1	1	Negative Genetic
YJR084W	YJR084W	Protein that forms a complex with Thp3p	genetic	1	1	1	Negative Genetic
EMC2	YJR088C	Member of conserved ER transmembrane complex	genetic	1	1	1	Negative Genetic
VPS24	YKL041W	One of four subunits of the ESCRT-III complex	genetic	1	1	1	Negative Genetic
VRP1	YLR337C	Verprolin, proline-rich actin-associated protein	genetic	1	1	1	Negative Genetic
MMS1	YPR164W	Subunit of E3 ubiquitin ligase complex involved in replication repair	genetic	1	1	1	Negative Genetic
VPS4	YPR173C	AAA-ATPase involved in multivesicular body (MVB) protein sorting	genetic	1	1	1	Negative Genetic
YBL081W	YBL081W	Non-essential protein of unknown function	genetic	1	1	1	Negative Genetic
HHF1	YBR009C	Histone H4	genetic	1	1	1	Negative Genetic
HHT1	YBR010W	Histone H3	genetic	1	1	1	Negative Genetic
UBS1	YBR165W	Ubiquitin-conjugating enzyme suppressor that regulates Cdc34p	genetic	1	1	1	Negative Genetic
MSI1	YBR195C	Subunit of chromatin assembly factor I (CAF-1)	genetic	1	1	1	Negative Genetic
THR4	YCR053W	Threonine synthase	genetic	1	1	1	Negative Genetic
SNF1	YDR477W	AMP-activated S/T protein kinase	genetic	1	1	1	Negative Genetic
MNT2	YGL257C	Mannosyltransferase	genetic	1	1	1	Negative Genetic
NNF2	YGR089W	Protein that exhibits physical and genetic interactions with Rpb8p	genetic	1	1	1	Negative Genetic
YCK1	YHR135C	Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform	genetic	1	1	1	Negative Genetic
DAL81	YIR023W	Positive regulator of genes in multiple nitrogen degradation pathways	genetic	1	1	1	Negative Genetic
TEF4	YKL081W	Gamma subunit of translational elongation factor eEF1B	genetic	1	1	1	Negative Genetic
PDC5	YLR134W	Minor isoform of pyruvate decarboxylase	genetic	1	1	1	Negative Genetic
GUF1	YLR289W	Mitochondrial matrix GTPase	genetic	1	1	1	Negative Genetic
CHS5	YLR330W	Component of the exomer complex	genetic	1	1	1	Negative Genetic
SKI2	YLR398C	Ski complex component and putative RNA helicase	genetic	1	1	1	Negative Genetic
DAT1	YML113W	DNA binding protein that recognizes oligo(dA).oligo(dT) tracts	genetic	1	1	1	Negative Genetic
SIW14	YNL032W	Inositol phosphatase involved in inositol pyrophosphate metabolism	genetic	1	1	1	Negative Genetic
SPE2	YOL052C	S-adenosylmethionine decarboxylase	genetic	1	1	1	Negative Genetic
SPE3	YPR069C	Spermidine synthase	genetic	1	1	1	Negative Genetic
FUN19	YAL034C	Non-essential protein of unknown function	genetic	1	1	1	Negative Genetic
HTB2	YBL002W	Histone H2B	genetic	1	1	1	Negative Genetic
LAA2	YBL010C	Clathrin adaptor (adaptin) accessory protein	genetic	1	1	1	Negative Genetic
NUP170	YBL079W	Subunit of inner ring of nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
KAP104	YBR017C	Transportin or cytosolic karyopherin beta 2	genetic	1	1	1	Negative Genetic
TSC3	YBR058C-A	Protein that stimulates the activity of serine palmitoyltransferase	genetic	1	1	1	Negative Genetic
MRPL36	YBR122C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
HSL7	YBR133C	Protein arginine N-methyltransferase	genetic	1	1	1	Negative Genetic
YBR137W	YBR137W	Protein with a role in ER delivery of tail-anchored membrane proteins	genetic	1	1	1	Negative Genetic
UMP1	YBR173C	Chaperone required for correct maturation of the 20S proteasome	genetic	1	1	1	Negative Genetic
SWD3	YBR175W	Essential subunit of the COMPASS (Set1C) complex	genetic	1	1	1	Negative Genetic
SSH1	YBR283C	Subunit of the Ssh1 translocon complex	genetic	1	1	1	Negative Genetic
GLK1	YCL040W	Glucokinase	genetic	1	1	1	Negative Genetic
INO2	YDR123C	Transcription factor	genetic	1	1	1	Negative Genetic
HOM2	YDR158W	Aspartic beta semi-aldehyde dehydrogenase	genetic	1	1	1	Negative Genetic
REF2	YDR195W	RNA-binding protein	genetic	1	1	1	Negative Genetic
IVY1	YDR229W	Phospholipid-binding protein that interacts with both Ypt7p and Vps33p	genetic	1	1	1	Negative Genetic
VPS52	YDR484W	Component of the GARP (Golgi-associated retrograde protein) complex	genetic	1	1	1	Negative Genetic
PXP1	YEL020C	Peroxisomal matrix protein	genetic	1	1	1	Negative Genetic
RIP1	YEL024W	Ubiquinol-cytochrome-c reductase	genetic	1	1	1	Negative Genetic
SPF1	YEL031W	P-type ATPase, ion transporter of the ER membrane	genetic	1	1	1	Negative Genetic
NPR2	YEL062W	Subunit of the Iml1p/SEACIT complex	genetic	1	1	1	Negative Genetic
YER039C-A	YER039C-A	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
YER053C-A	YER053C-A	Protein of unknown function	genetic	1	1	1	Negative Genetic
PIC2	YER053C	Mitochondrial copper and phosphate carrier	genetic	1	1	1	Negative Genetic
FCY22	YER060W-A	Putative purine-cytosine permease	genetic	1	1	1	Negative Genetic
ICL1	YER065C	Isocitrate lyase	genetic	1	1	1	Negative Genetic
SSA4	YER103W	Heat shock protein that is highly induced upon stress	genetic	1	1	1	Negative Genetic
KAP123	YER110C	Karyopherin beta	genetic	1	1	1	Negative Genetic
SWI4	YER111C	DNA binding component of the SBF complex (Swi4p-Swi6p)	genetic	1	1	1	Negative Genetic
SCS2	YER120W	Integral ER membrane protein, regulates phospholipid metabolism	genetic	1	1	1	Negative Genetic
RPH1	YER169W	JmjC domain-containing histone demethylase	genetic	1	1	1	Negative Genetic
DEG1	YFL001W	tRNA:pseudouridine synthase	genetic	1	1	1	Negative Genetic
MET10	YFR030W	Subunit alpha of assimilatory sulfite reductase	genetic	1	1	1	Negative Genetic
TYW3	YGL050W	tRNA methyltransferase required for synthesis of wybutosine	genetic	1	1	1	Negative Genetic
CDC55	YGL190C	Regulatory subunit B of protein phosphatase 2A (PP2A)	genetic	1	1	1	Negative Genetic
NMA2	YGR010W	Nicotinic acid mononucleotide adenylyltransferase	genetic	1	1	1	Negative Genetic
UGA1	YGR019W	Gamma-aminobutyrate (GABA) transaminase	genetic	1	1	1	Negative Genetic
DBF2	YGR092W	Ser/Thr kinase involved in transcription and stress response	genetic	1	1	1	Negative Genetic
SMI1	YGR229C	Protein involved in the regulation of cell wall synthesis	genetic	1	1	1	Negative Genetic
YLF2	YHL014C	Protein of unknown function	genetic	1	1	1	Negative Genetic
MCO14	YHL018W	Putative 4a-hydroxytetrahydrobiopterin dehydratase	genetic	1	1	1	Negative Genetic
COX6	YHR051W	Subunit VI of cytochrome c oxidase (Complex IV)	genetic	1	1	1	Negative Genetic
SFB3	YHR098C	Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat	genetic	1	1	1	Negative Genetic
TRA1	YHR099W	Subunit of SAGA and NuA4 histone acetyltransferase complexes	genetic	1	1	1	Negative Genetic
SET1	YHR119W	Histone methyltransferase, subunit of the COMPASS (Set1C) complex	genetic	1	1	1	Negative Genetic
SCH9	YHR205W	AGC family protein kinase	genetic	1	1	1	Negative Genetic
YJL136W-A	YJL136W-A	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
JJJ2	YJL162C	Protein of unknown function	genetic	1	1	1	Negative Genetic
TPK1	YJL164C	cAMP-dependent protein kinase catalytic subunit	genetic	1	1	1	Negative Genetic
PAU1	YJL223C	Member of the seripauperin multigene family	genetic	1	1	1	Negative Genetic
OPI3	YJR073C	Methylene-fatty-acyl-phospholipid synthase	genetic	1	1	1	Negative Genetic
IML1	YJR138W	GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex	genetic	1	1	1	Negative Genetic
MRT4	YKL009W	Protein involved in mRNA turnover and ribosome assembly	genetic	1	1	1	Negative Genetic
NFU1	YKL040C	Protein involved in Fe-S cluster transfer to mitochondrial clients	genetic	1	1	1	Negative Genetic
LHS1	YKL073W	Molecular chaperone of the endoplasmic reticulum lumen	genetic	1	1	1	Negative Genetic
YKL096C-B	YKL096C-B	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
RAD27	YKL113C	5' to 3' exonuclease, 5' flap endonuclease	genetic	1	1	1	Negative Genetic
POM34	YLR018C	Subunit of the transmembrane ring of the nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
PER33	YLR064W	Protein that localizes to the endoplasmic reticulum	genetic	1	1	1	Negative Genetic
YLR156W	YLR156W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
HRI1	YLR301W	Protein of unknown function that interacts with Sec72p and Hrr25p	genetic	1	1	1	Negative Genetic
MET17	YLR303W	O-acetyl homoserine-O-acetyl serine sulfhydrylase	genetic	1	1	1	Negative Genetic
TRM9	YML014W	tRNA methyltransferase	genetic	1	1	1	Negative Genetic
CYB2	YML054C	Cytochrome b2 (L-lactate cytochrome-c oxidoreductase)	genetic	1	1	1	Negative Genetic
DUS1	YML080W	Dihydrouridine synthase	genetic	1	1	1	Negative Genetic
YMR001C-A	YMR001C-A	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
TVP18	YMR071C	Integral membrane protein	genetic	1	1	1	Negative Genetic
CTF18	YMR078C	Subunit of a complex with Ctf8p	genetic	1	1	1	Negative Genetic
SPT21	YMR179W	Protein with a role in transcriptional silencing	genetic	1	1	1	Negative Genetic
MIN3	YMR182W-A	Mitochondrial protein of unknown function	genetic	1	1	1	Negative Genetic
SCJ1	YMR214W	One of several homologs of bacterial chaperone DnaJ	genetic	1	1	1	Negative Genetic
GAS3	YMR215W	Putative 1,3-beta-glucanosyltransferase	genetic	1	1	1	Negative Genetic
YMR226C	YMR226C	NADP(+)-dependent serine dehydrogenase and carbonyl reductase	genetic	1	1	1	Negative Genetic
DFG5	YMR238W	Putative mannosidase	genetic	1	1	1	Negative Genetic
YMR247W-A	YMR247W-A	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
PPA2	YMR267W	Mitochondrial inorganic pyrophosphatase	genetic	1	1	1	Negative Genetic
VAC7	YNL054W	Integral vacuolar membrane protein	genetic	1	1	1	Negative Genetic
MDG1	YNL173C	Plasma membrane protein	genetic	1	1	1	Negative Genetic
RAD50	YNL250W	Subunit of MRX complex with Mre11p and Xrs2p	genetic	1	1	1	Negative Genetic
CLA4	YNL298W	Cdc42p-activated signal transducing kinase	genetic	1	1	1	Negative Genetic
YPT11	YNL304W	Rab GTPase	genetic	1	1	1	Negative Genetic
SKP2	YNL311C	F-box protein of unknown function	genetic	1	1	1	Negative Genetic
RPD3	YNL330C	Histone deacetylase, component of both the Rpd3S and Rpd3L complexes	genetic	1	1	1	Negative Genetic
CSI2	YOL007C	Protein of unknown function	genetic	1	1	1	Negative Genetic
PRS5	YOL061W	5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase	genetic	1	1	1	Negative Genetic
IRA2	YOL081W	GTPase-activating protein	genetic	1	1	1	Negative Genetic
MDH2	YOL126C	Cytoplasmic malate dehydrogenase	genetic	1	1	1	Negative Genetic
IMA2	YOL157C	Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase)	genetic	1	1	1	Negative Genetic
YOR072W-B	YOR072W-B	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
ELG1	YOR144C	Subunit of an alternative replication factor C complex	genetic	1	1	1	Negative Genetic
MDM32	YOR147W	Mitochondrial inner membrane protein with similarity to Mdm31p	genetic	1	1	1	Negative Genetic
YIG1	YPL201C	Protein that interacts with glycerol 3-phosphatase	genetic	1	1	1	Negative Genetic
TPK2	YPL203W	cAMP-dependent protein kinase catalytic subunit	genetic	1	1	1	Negative Genetic
FUM1	YPL262W	Fumarase	genetic	1	1	1	Negative Genetic
YPR027C	YPR027C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
YKU80	YMR106C	Subunit of telomeric Ku complex (Yku70p-Yku80p)	genetic	1	1	1	Phenotypic Enhancement
SIR2	YDL042C	Conserved NAD+ dependent histone deacetylase of the Sirtuin family	genetic	1	1	1	Synthetic Growth Defect
SLP1	YOR154W	Glycosylated integral ER membrane protein of unknown function	genetic	1	1	1	Phenotypic Suppression
PAT1	YCR077C	Deadenylation-dependent mRNA-decapping factor	genetic	1	1	1	Positive Genetic
PNG1	YPL096W	Conserved peptide N-glycanase	genetic	1	1	1	Synthetic Rescue
SIZ1	YDR409W	SUMO E3 ligase	genetic	1	1	1	Phenotypic Suppression
PPZ1	YML016C	Serine/threonine protein phosphatase Z, isoform of Ppz2p	genetic	1	1	1	Synthetic Growth Defect
PPZ2	YDR436W	Serine/threonine protein phosphatase Z, isoform of Ppz1p	genetic	1	1	1	Synthetic Growth Defect
CDC39	YCR093W	Subunit of the CCR4-NOT1 core complex	genetic	1	1	1	Negative Genetic
AOS1	YPR180W	Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p	genetic	1	1	1	Negative Genetic
APC1	YNL172W	Largest subunit of the Anaphase-Promoting Complex/Cyclosome	genetic	1	1	1	Negative Genetic
ATG14	YBR128C	Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I	physical	1	1	1	Affinity Capture-MS
APL3	YBL037W	Alpha-adaptin	genetic	1	1	1	Negative Genetic
ARC35	YNR035C	Subunit of the ARP2/3 complex	genetic	1	1	1	Positive Genetic
ARP3	YJR065C	Essential component of the Arp2/3 complex	genetic	1	1	1	Positive Genetic
BET3	YKR068C	Core component of transport protein particle (TRAPP) complexes I-III	genetic	1	1	1	Negative Genetic
ASC1	YMR116C	G-protein beta subunit and guanine dissociation inhibitor for Gpa2p	physical	1	1	1	Affinity Capture-MS
BEM2	YER155C	Rho GTPase activating protein (RhoGAP)	genetic	1	1	1	Negative Genetic
CDC14	YFR028C	Protein phosphatase required for mitotic exit	physical	1	1	1	Affinity Capture-MS
CDC14	YFR028C	Protein phosphatase required for mitotic exit	genetic	1	1	1	Negative Genetic
CDC11	YJR076C	Component of the septin ring that is required for cytokinesis	genetic	1	1	1	Negative Genetic
CDC12	YHR107C	Component of the septin ring that is required for cytokinesis	genetic	1	1	1	Negative Genetic
AEP2	YMR282C	Mitochondrial protein	genetic	1	1	1	Negative Genetic
ADA2	YDR448W	Transcription coactivator	physical	1	1	1	Affinity Capture-MS
ARP8	YOR141C	Nuclear actin-related protein involved in chromatin remodeling	genetic	1	1	1	Synthetic Growth Defect
ATG18	YFR021W	Phosphoinositide binding protein	physical	1	1	1	Affinity Capture-MS
AFG2	YLR397C	ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex	genetic	1	1	1	Positive Genetic
BUD21	YOR078W	Component of small ribosomal subunit (SSU) processosome	genetic	1	1	1	Positive Genetic
CCT2	YIL142W	Subunit beta of the cytosolic chaperonin Cct ring complex	genetic	1	1	1	Negative Genetic
CDC25	YLR310C	Membrane bound guanine nucleotide exchange factor	genetic	1	1	1	Negative Genetic
CCT8	YJL008C	Subunit of the cytosolic chaperonin Cct ring complex	genetic	1	1	1	Negative Genetic
CCT6	YDR188W	Subunit of the cytosolic chaperonin Cct ring complex	genetic	1	1	1	Negative Genetic
ATG9	YDL149W	Transmembrane protein involved in forming Cvt and autophagic vesicles	physical	1	1	1	Affinity Capture-MS
BCY1	YIL033C	Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA)	genetic	1	1	1	Negative Genetic
ATG29	YPL166W	Autophagy-specific protein	physical	1	1	1	Affinity Capture-MS
ATG31	YDR022C	Autophagy-specific protein required for autophagosome formation	physical	1	1	1	Affinity Capture-MS
ASA1	YPR085C	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	1	1	1	Positive Genetic
BUD13	YGL174W	Subunit of the RES complex	genetic	1	1	1	Positive Genetic
ADK1	YDR226W	Adenylate kinase, required for purine metabolism	genetic	1	1	1	Negative Genetic
ACS2	YLR153C	Acetyl-coA synthetase isoform	genetic	1	1	1	Negative Genetic
ARE2	YNR019W	Acyl-CoA:sterol acyltransferase	genetic	1	1	1	Negative Genetic
BUD32	YGR262C	Protein kinase	genetic	1	1	1	Dosage Growth Defect
ART10	YLR392C	Protein of unknown function that contains 2 PY motifs	genetic	1	1	1	Negative Genetic
CDC37	YDR168W	Essential Hsp90p co-chaperone	genetic	1	1	1	Negative Genetic
BEM4	YPL161C	Protein involved in establishment of cell polarity and bud emergence	genetic	1	1	1	Positive Genetic
CCE1	YKL011C	Mitochondrial cruciform cutting endonuclease	genetic	1	1	1	Negative Genetic
AFG3	YER017C	Mitochondrial inner membrane m-AAA protease component	genetic	1	1	1	Negative Genetic
ATG1	YGL180W	Protein serine/threonine kinase	physical	1	1	1	Affinity Capture-MS
ATG13	YPR185W	Regulatory subunit of the Atg1p signaling complex	physical	1	1	1	Affinity Capture-MS
ATG27	YJL178C	Type I membrane protein involved in autophagy and the Cvt pathway	physical	1	1	1	Affinity Capture-MS
CDC34	YDR054C	Ubiquitin-conjugating enzyme (E2)	genetic	1	1	1	Synthetic Growth Defect
AIM4	YBR194W	Protein proposed to be associated with the nuclear pore complex	physical	1	1	1	Affinity Capture-MS
BRF1	YGR246C	TFIIIB B-related factor	physical	1	1	1	Affinity Capture-MS
BRE5	YNR051C	Ubiquitin protease cofactor	genetic	1	1	1	Negative Genetic
APN1	YKL114C	Major apurinic/apyrimidinic endonuclease	genetic	1	1	1	Negative Genetic
ALF1	YNL148C	Alpha-tubulin folding protein	genetic	1	1	1	Negative Genetic
ATG23	YLR431C	Peripheral membrane protein required for autophagy and CVT	physical	1	1	1	Affinity Capture-MS
BFR1	YOR198C	Component of mRNP complexes associated with polyribosomes	physical	1	1	1	Affinity Capture-RNA
BRN1	YBL097W	Subunit of the condensin complex	genetic	1	1	1	Negative Genetic
ATG2	YNL242W	Peripheral membrane protein required for autophagic vesicle formation	physical	1	1	1	Affinity Capture-MS
ATG2	YNL242W	Peripheral membrane protein required for autophagic vesicle formation	genetic	1	1	1	Negative Genetic
BAT2	YJR148W	Cytosolic branched-chain amino acid (BCAA) aminotransferase	genetic	1	1	1	Negative Genetic
BSD2	YBR290W	Heavy metal ion homeostasis protein	genetic	1	1	1	Negative Genetic
BET4	YJL031C	Alpha subunit of Type II geranylgeranyltransferase	genetic	1	1	1	Negative Genetic
AQR1	YNL065W	Plasma membrane transporter of the major facilitator superfamily	genetic	1	1	1	Negative Genetic
ALG1	YBR110W	Mannosyltransferase	genetic	1	1	1	Negative Genetic
BUL2	YML111W	Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex	genetic	1	1	1	Negative Genetic
AQY3	YFL054C	Putative channel-like protein	genetic	1	1	1	Negative Genetic
ATG33	YLR356W	Mitochondrial mitophagy-specific protein	genetic	1	1	1	Negative Genetic
CAJ1	YER048C	Nuclear type II J heat shock protein of the E. coli dnaJ family	genetic	1	1	1	Positive Genetic
AIM26	YKL037W	Protein of unknown function	genetic	1	1	1	Negative Genetic
APJ1	YNL077W	Hsp40 chaperone with a role in SUMO-mediated protein degradation	physical	1	1	1	Affinity Capture-MS
CCW22	YDR134C	Cell wall protein	genetic	1	1	1	Negative Genetic
APE4	YHR113W	Cytoplasmic aspartyl aminopeptidase with possible vacuole function	genetic	1	1	1	Negative Genetic
ATG15	YCR068W	Phospholipase	genetic	1	1	1	Negative Genetic
CCC2	YDR270W	Cu(+2)-transporting P-type ATPase	genetic	1	1	1	Negative Genetic
AGC1	YPR021C	Mitochondrial amino acid transporter	genetic	1	1	1	Negative Genetic
BCD1	YHR040W	Essential protein required for the accumulation of box C/D snoRNA	genetic	1	1	1	Positive Genetic
ADF1	YCL058W-A	Transcriptional repressor encoded by the FYV5 antisense strand	genetic	1	1	1	Negative Genetic