Standard name Systematic name Name description Description
SWI6 YLR182W Transcription cofactor Transcription cofactor; forms complexes with Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; also binds Stb1p to regulate transcription at START; cell wall stress induces phosphorylation by Mpk1p, which regulates Swi6p localization; required for the unfolded protein response, independently of its known transcriptional coactivators
Visualize the interactome of SWI6
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 146

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.111 0.108 NaN
Nucleolus 0.166 0.112 NaN
Nucleus 0.857 0.884 0.890
Cytoplasm NaN NaN 0.057

GFP localization & abundance

GFP localization GFP abundance
nucleus 3340

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SWI6 2 3 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) physical 19 4 14 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, PCA, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 12 5 11 Dosage Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Dosage Rescue, Negative Genetic, Synthetic Lethality, Dosage Rescue
MBP1 YDL056W Transcription factor physical 10 5 7 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, PCA, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
ELP3 YPL086C Subunit of Elongator complex genetic 7 2 6 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
WHI5 YOR083W Repressor of G1 transcription physical 7 3 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 6 3 5 Dosage Rescue, Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 6 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 6 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 5 2 5 Biochemical Activity, PCA, Biochemical Activity, PCA, Biochemical Activity
ELP2 YGR200C Subunit of Elongator complex genetic 5 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 5 3 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Positive Genetic
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 4 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 4 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 4 2 4 Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 4 1 4 Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 4 3 3 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Growth Defect
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 4 3 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
SNF1 YDR477W AMP-activated S/T protein kinase physical 4 1 2 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RAD51 YER095W Strand exchange protein genetic 3 3 3 Synthetic Lethality, Positive Genetic, Dosage Rescue
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 3 3 3 Phenotypic Suppression, Synthetic Growth Defect, Positive Genetic
RME1 YGR044C Zinc finger protein involved in control of meiosis genetic 3 3 3 Dosage Rescue, Synthetic Lethality, Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 3 2 3 Synthetic Lethality, Negative Genetic, Synthetic Lethality
LSM1 YJL124C Lsm (Like Sm) protein genetic 3 2 3 Negative Genetic, Negative Genetic, Positive Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 3 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 3 2 3 Positive Genetic, Positive Genetic, Phenotypic Suppression
CTF4 YPR135W Chromatin-associated protein genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 3 2 3 Phenotypic Suppression, Negative Genetic, Negative Genetic
RAD53 YPL153C DNA damage response kinase physical 3 2 3 Biochemical Activity, Biochemical Activity, Affinity Capture-MS
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 3 2 3 Positive Genetic, Negative Genetic, Negative Genetic
MSN5 YDR335W Karyopherin genetic 3 2 3 Synthetic Lethality, Synthetic Lethality, Negative Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 3 2 3 Positive Genetic, Positive Genetic, Phenotypic Suppression
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 3 2 3 Phenotypic Enhancement, Negative Genetic, Negative Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 3 2 3 Positive Genetic, Negative Genetic, Negative Genetic
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start physical 3 2 3 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 3 2 3 Phenotypic Suppression, Positive Genetic, Positive Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
NRM1 YNR009W Transcriptional co-repressor of MBF-regulated gene expression physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 3 2 3 Synthetic Lethality, Synthetic Lethality, Negative Genetic
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase physical 3 3 2 Affinity Capture-Western, Reconstituted Complex, Biochemical Activity
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 3 1 2 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
RTT109 YLL002W Histone acetyltransferase genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
AGA1 YNR044W Anchorage subunit of a-agglutinin of a-cells regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase regulation 2 2 2 chromatin immunoprecipitation-chip evidence, northern blot evidence
CWP1 YKL096W Cell wall mannoprotein that localizes to birth scars of daughter cells regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 2 2 2 chromatin immunoprecipitation-chip evidence, northern blot evidence
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle regulation 2 2 2 chromatin immunoprecipitation-chip evidence, S1 nuclease protection assay evidence
RNR1 YER070W Major isoform of large subunit of ribonucleotide-diphosphate reductase regulation 2 2 2 chromatin immunoprecipitation-chip evidence, S1 nuclease protection assay evidence
CDC21 YOR074C Thymidylate synthase regulation 2 2 2 chromatin immunoprecipitation-chip evidence, S1 nuclease protection assay evidence
LEO1 YOR123C Component of the Paf1 complex genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 2 2 2 Synthetic Lethality, Negative Genetic
SSD1 YDR293C Translational repressor genetic 2 2 2 Synthetic Lethality, Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 2 2 2 Biochemical Activity, Co-crystal Structure
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 2 2 2 Negative Genetic, Synthetic Lethality
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 2 2 2 Phenotypic Suppression, Positive Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 2 2 2 Synthetic Lethality, Positive Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
FES1 YBR101C Hsp70 (Ssa1p) nucleotide exchange factor genetic 2 2 2 Phenotypic Suppression, Negative Genetic
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 2 2 2 Negative Genetic, Synthetic Lethality
BUD13 YGL174W Subunit of the RES complex genetic 2 2 2 Positive Genetic, Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 2 2 2 Synthetic Lethality, Positive Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 2 2 2 Negative Genetic, Positive Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 2 2 2 Synthetic Rescue, Positive Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p genetic 2 2 2 Positive Genetic, Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 2 2 2 Synthetic Growth Defect, Dosage Growth Defect
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
THG1 YGR024C tRNAHis guanylyltransferase genetic 2 2 2 Positive Genetic, Negative Genetic
WHI3 YNL197C RNA binding protein that modulates mRNA stability genetic 2 2 2 Positive Genetic, Synthetic Rescue
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
UBI4 YLL039C Ubiquitin genetic 2 2 2 Dosage Rescue, Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 2 2 2 Synthetic Rescue, Positive Genetic
PFY1 YOR122C Profilin genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
REV7 YIL139C Accessory subunit of DNA polymerase zeta genetic 2 2 2 Dosage Rescue, Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 2 2 2 Synthetic Lethality, Positive Genetic
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 2 2 2 Synthetic Growth Defect, Dosage Growth Defect
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
SSE2 YBR169C Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family genetic 2 2 2 Phenotypic Suppression, Positive Genetic
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 2 2 2 Negative Genetic, Synthetic Lethality
CDC73 YLR418C Component of the Paf1p complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 2 1 2 Negative Genetic, Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 2 1 2 Positive Genetic, Positive Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 2 1 2 Positive Genetic, Positive Genetic
PAB1 YER165W Poly(A) binding protein genetic 2 1 2 Dosage Rescue, Dosage Rescue
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
PSY2 YNL201C Subunit of protein phosphatase PP4 complex genetic 2 1 2 Negative Genetic, Negative Genetic
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 2 1 2 Positive Genetic, Positive Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 2 1 2 Negative Genetic, Negative Genetic
BOI2 YER114C Protein involved in polar growth genetic 2 1 2 Positive Genetic, Positive Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
BNI1 YNL271C Formin genetic 2 1 2 Negative Genetic, Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 1 2 Negative Genetic, Negative Genetic
FET5 YFL041W Multicopper oxidase genetic 2 1 2 Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 2 1 2 Positive Genetic, Positive Genetic
PCI8 YIL071C Possible shared subunit of Cop9 signalosome (CSN) and eIF3 genetic 2 1 2 Negative Genetic, Negative Genetic
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A genetic 2 1 2 Negative Genetic, Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 2 1 2 Negative Genetic, Negative Genetic
SCJ1 YMR214W One of several homologs of bacterial chaperone DnaJ genetic 2 1 2 Positive Genetic, Positive Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 1 2 Negative Genetic, Negative Genetic
FYV10 YIL097W Subunit of GID complex genetic 2 1 2 Negative Genetic, Negative Genetic
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 2 1 2 Dosage Rescue, Dosage Rescue
AAC1 YMR056C Mitochondrial inner membrane ADP/ATP translocator genetic 2 1 2 Positive Genetic, Positive Genetic
AIP1 YMR092C Actin cortical patch component genetic 2 1 2 Positive Genetic, Positive Genetic
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 2 1 2 Negative Genetic, Negative Genetic
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase genetic 2 1 2 Positive Genetic, Positive Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
GDH2 YDL215C NAD(+)-dependent glutamate dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
APM4 YOL062C Cargo-binding mu subunit of AP-2 genetic 2 1 2 Positive Genetic, Positive Genetic
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 2 1 2 Negative Genetic, Negative Genetic
CLB1 YGR108W B-type cyclin involved in cell cycle progression genetic 2 1 2 Positive Genetic, Positive Genetic
CHL1 YPL008W Probable DNA helicase genetic 2 1 2 Negative Genetic, Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 2 1 2 Positive Genetic, Positive Genetic
SAC3 YDR159W mRNA export factor genetic 2 1 2 Negative Genetic, Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation genetic 2 1 2 Negative Genetic, Negative Genetic
YAK1 YJL141C Serine-threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 2 1 2 Negative Genetic, Negative Genetic
TRM1 YDR120C tRNA methyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
YDR514C YDR514C Protein of unknown function that localizes to mitochondria genetic 2 1 2 Negative Genetic, Negative Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 2 1 2 Negative Genetic, Negative Genetic
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 2 1 2 Negative Genetic, Negative Genetic
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation genetic 2 1 2 Positive Genetic, Positive Genetic
VAC14 YLR386W Enzyme regulator genetic 2 1 2 Negative Genetic, Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 2 1 2 Negative Genetic, Negative Genetic
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p genetic 2 1 2 Negative Genetic, Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector genetic 2 1 2 Positive Genetic, Positive Genetic
AZF1 YOR113W Zinc-finger transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
STB5 YHR178W Transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
CST26 YBR042C Acyltransferase genetic 2 1 2 Positive Genetic, Positive Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 2 1 2 Negative Genetic, Negative Genetic
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 2 1 2 Negative Genetic, Negative Genetic
SQS1 YNL224C Protein that stimulates the ATPase and helicase activities of Prp43p genetic 2 1 2 Negative Genetic, Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 2 1 2 Positive Genetic, Positive Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 2 1 2 Positive Genetic, Positive Genetic
ITR1 YDR497C Myo-inositol transporter genetic 2 1 2 Negative Genetic, Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 2 1 2 Positive Genetic, Positive Genetic
HXT15 YDL245C Putative transmembrane polyol transporter genetic 2 1 2 Positive Genetic, Positive Genetic
GYP8 YFL027C GTPase-activating protein for yeast Rab family members genetic 2 1 2 Positive Genetic, Positive Genetic
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 2 1 2 Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 1 Positive Genetic, Negative Genetic
MBP1 YDL056W Transcription factor genetic 2 2 1 Synthetic Rescue, Dosage Rescue
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 2 2 1 Phenotypic Suppression, Synthetic Growth Defect
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 2 2 1 Phenotypic Suppression, Synthetic Growth Defect
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 2 2 1 Affinity Capture-Western, Biochemical Activity
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex genetic 2 2 1 Phenotypic Suppression, Synthetic Growth Defect
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 2 2 1 Phenotypic Enhancement, Synthetic Growth Defect
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) physical 2 2 1 Affinity Capture-Western, Protein-peptide
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
SRB7 YDR308C Subunit of the RNA polymerase II mediator complex genetic 2 2 1 Phenotypic Suppression, Synthetic Growth Defect
SRL3 YKR091W Repressor of transcription at Start physical 2 2 1 Co-localization, Affinity Capture-Western
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
ADA2 YDR448W Transcription coactivator genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NUM1 YDR150W Protein required for nuclear migration physical 2 1 1 Two-hybrid, Two-hybrid
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CIN8 YEL061C Bipolar kinesin motor protein genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ADI1 YMR009W Acireductone dioxygenease involved in methionine salvage pathway regulation 1 1 1 DNA to cDNA expression microarray evidence
AGE1 YDR524C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MNN5 YJL186W Alpha-1,2-mannosyltransferase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MNN1 YER001W Alpha-1,3-mannosyltransferase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARO9 YHR137W Aromatic aminotransferase II regulation 1 1 1 DNA to cDNA expression microarray evidence
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERG3 YLR056W C-5 sterol desaturase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CLA4 YNL298W Cdc42p-activated signal transducing kinase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SVS1 YPL163C Cell wall and vacuolar protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SCW10 YMR305C Cell wall protein with similarity to glucanases regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SCW4 YGR279C Cell wall protein with similarity to glucanases regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CRH1 YGR189C Chitin transglycosylase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UTR2 YEL040W Chitin transglycosylase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ENV9 YOR246C Conserved oxidoreductase involved in lipid droplet morphology regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NOP16 YER002W Constituent of 66S pre-ribosomal particles regulation 1 1 1 DNA to cDNA expression microarray evidence
CWP2 YKL096W-A Covalently linked cell wall mannoprotein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PCL2 YDL127W Cyclin, interacts with cyclin-dependent kinase Pho85p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SRS2 YJL092W DNA helicase and DNA-dependent ATPase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC45 YLR103C DNA replication initiation factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PPN1 YDR452W Dual endo- and exopolyphosphatase with a role in phosphate metabolism regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ELO1 YJL196C Elongase I, medium-chain acyl elongase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC6 YJL194W Essential ATP-binding protein required for DNA replication regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HCM1 YCR065W Forkhead transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle regulation 1 1 1 S1 nuclease protection assay evidence
ECM38 YLR299W Gamma-glutamyltranspeptidase regulation 1 1 1 DNA to cDNA expression microarray evidence
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TOS6 YNL300W Glycosylphosphatidylinositol-dependent cell wall protein regulation 1 1 1 DNA to cDNA expression microarray evidence
GOR1 YNL274C Glyoxylate reductase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GYP7 YDL234C GTPase-activating protein for yeast Rab family members regulation 1 1 1 DNA to cDNA expression microarray evidence
HXK2 YGL253W Hexokinase isoenzyme 2 regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HTA1 YDR225W Histone H2A regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HTB1 YDR224C Histone H2B regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YHP1 YDR451C Homeobox transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YOX1 YML027W Homeobox transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKG6 YHR149C Integral membrane protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TSL1 YML100W Large subunit of trehalose 6-phosphate synthase/phosphatase complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BNI5 YNL166C Linker protein responsible for recruitment of myosin to the bud neck regulation 1 1 1 DNA to cDNA expression microarray evidence
PRY1 YJL079C Lipid binding protein regulation 1 1 1 DNA to cDNA expression microarray evidence
CAR2 YLR438W L-ornithine transaminase (OTAse) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AMF1 YOR378W Low affinity NH4+ transporter regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LSM4 YER112W Lsm (Like Sm) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane regulation 1 1 1 chromatin immunoprecipitation-chip evidence
EXG1 YLR300W Major exo-1,3-beta-glucanase of the cell wall regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SRL1 YOR247W Mannoprotein that exhibits a tight association with the cell wall regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPO20 YMR017W Meiosis-specific subunit of the t-SNARE complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PET54 YGR222W Mitochondrial inner membrane protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UTH1 YKR042W Mitochondrial inner membrane protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DIN7 YDR263C Mitochondrial nuclease functioning in DNA repair and replication regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NUD1 YOR373W Mitotic exit network (MEN) scaffold protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MPT5 YGL178W mRNA-binding protein of the PUF family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSB2 YGR014W Mucin family member involved in various signaling pathways regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YBL029W YBL029W Non-essential protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family regulation 1 1 1 DNA to cDNA expression microarray evidence
ASF1 YJL115W Nucleosome assembly factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MID2 YLR332W O-glycosylated plasma membrane protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PEX28 YHR150W Peroxisomal integral membrane peroxin regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PDR16 YNL231C Phosphatidylinositol transfer protein (PITP) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SSU1 YPL092W Plasma membrane sulfite pump involved in sulfite metabolism regulation 1 1 1 DNA to cDNA expression microarray evidence
KCH1 YJR054W Potassium transporter that mediates K+ influx regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GAT2 YMR136W Protein containing GATA family zinc finger motifs regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUD9 YGR041W Protein involved in bud-site selection regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TOS2 YGR221C Protein involved in localization of Cdc24p to the site of bud growth regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NCA3 YJL116C Protein involved in mitochondrion organization regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HLR1 YDR528W Protein involved in regulation of cell wall composition and integrity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKS3 YMR306W Protein involved in spore wall assembly regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RBA50 YDR527W Protein involved in transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TOS3 YGL179C Protein kinase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWE1 YJL187C Protein kinase that regulates the G2/M transition regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIM1 YIL123W Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IRC22 YEL001C Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YBL029C-A YBL029C-A Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YLR297W YLR297W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
CUE4 YML101C Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SNA2 YDR525W-A Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BOP3 YNL042W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YER158C YER158C Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
TMA10 YLR327C Protein of unknown function that associates with ribosomes regulation 1 1 1 DNA to cDNA expression microarray evidence
PTH4 YOL114C Protein similar to the human peptidyl-tRNA hydrolase gene ICT1 regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MRX16 YDR132C Protein that associates with the large mitoribosomal subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PXL1 YKR090W Protein that localizes to sites of polarized growth regulation 1 1 1 DNA to cDNA expression microarray evidence
DIF1 YLR437C Protein that regulates nuclear import of Rnr2p and Rnr4p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT21 YMR179W Protein with a role in transcriptional silencing regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERP3 YDL018C Protein with similarity to Emp24p and Erv25p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
THI22 YPR121W Protein with similarity to hydroxymethylpyrimidine phosphate kinases regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ATR2 YMR279C Putative boron transporter involved in boron efflux and resistance regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MRX14 YDR115W Putative mitochondrial ribosomal protein of the large subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YKL097C YKL097C Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
LCL1 YPL056C Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YKL096C-B YKL096C-B Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YML100W-A YML100W-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LCL2 YLR104W Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YDR524W-C YDR524W-C Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YDR524C-B YDR524C-B Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YOR338W YOR338W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAR009C YAR009C Retrotransposon TYA Gag and TYB Pol genes regulation 1 1 1 DNA to cDNA expression microarray evidence
YML045W YML045W Retrotransposon TYA Gag and TYB Pol genes regulation 1 1 1 DNA to cDNA expression microarray evidence
YGR109W-B YGR109W-B Retrotransposon TYA Gag and TYB Pol genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YML045W-A YML045W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 DNA to cDNA expression microarray evidence
YML040W YML040W Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 DNA to cDNA expression microarray evidence
YMR051C YMR051C Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 DNA to cDNA expression microarray evidence
YNL284C-A YNL284C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 DNA to cDNA expression microarray evidence
YPL257W-A YPL257W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 DNA to cDNA expression microarray evidence
YER159C-A YER159C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 DNA to cDNA expression microarray evidence
YGR027W-A YGR027W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 DNA to cDNA expression microarray evidence
YGR109W-A YGR109W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YHL009W-A YHL009W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 DNA to cDNA expression microarray evidence
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PDS1 YDR113C Securin regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HO YDL227C Site-specific endonuclease regulation 1 1 1 electrophoretic mobility shift assay evidence
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GID8 YMR135C Subunit of GID Complex, binds strongly to central component Vid30p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IRR1 YIL026C Subunit of the cohesin complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SLM4 YBR077C Subunit of the EGO/GSE complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
KRE29 YER038C Subunit of the SMC5-SMC6 complex regulation 1 1 1 DNA to cDNA expression microarray evidence
VHR1 YIL056W Transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NDD1 YOR372C Transcriptional activator essential for nuclear division regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NRM1 YNR009W Transcriptional co-repressor of MBF-regulated gene expression regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UFE1 YOR075W t-SNARE protein required for retrograde vesicular traffic regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity regulation 1 1 1 DNA to cDNA expression microarray evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Phenotypic Suppression
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 1 1 1 Negative Genetic
MCM22 YJR135C Outer kinetochore protein and component of the Ctf3 subcomplex genetic 1 1 1 Negative Genetic
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Synthetic Lethality
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Positive Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin genetic 1 1 1 Positive Genetic
BRX1 YOL077C Nucleolar protein genetic 1 1 1 Negative Genetic
NOG1 YPL093W Putative GTPase genetic 1 1 1 Positive Genetic
NOP4 YPL043W Nucleolar protein genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
PFK27 YOL136C 6-phosphofructo-2-kinase genetic 1 1 1 Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome physical 1 1 1 Co-purification
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Positive Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 1 1 1 Positive Genetic
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 1 1 1 Negative Genetic
MES1 YGR264C Methionyl-tRNA synthetase genetic 1 1 1 Negative Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Positive Genetic
MTR4 YJL050W RNA duplex-sensing translocase genetic 1 1 1 Positive Genetic
MDM20 YOL076W Non-catalytic subunit of the NatB N-terminal acetyltransferase genetic 1 1 1 Negative Genetic
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress genetic 1 1 1 Positive Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
DIS3 YOL021C Exosome core complex catalytic subunit genetic 1 1 1 Positive Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
RPC19 YNL113W RNA polymerase subunit AC19 genetic 1 1 1 Negative Genetic
RPC31 YNL151C RNA polymerase III subunit C31 genetic 1 1 1 Negative Genetic
RPO31 YOR116C RNA polymerase III largest subunit C160 genetic 1 1 1 Negative Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Negative Genetic
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex genetic 1 1 1 Positive Genetic
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Negative Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex physical 1 1 1 Two-hybrid
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
SRB4 YER022W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Suppression
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Synthetic Rescue
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 1 1 1 Positive Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Positive Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Positive Genetic
RLI1 YDR091C Essential Fe-S protein genetic 1 1 1 Positive Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Negative Genetic
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
CAP1 YKL007W Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 1 1 1 Positive Genetic
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase genetic 1 1 1 Positive Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Positive Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Positive Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Positive Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Negative Genetic
EMP24 YGL200C Component of the p24 complex genetic 1 1 1 Positive Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Positive Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Positive Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Negative Genetic
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
BDF2 YDL070W Protein involved in transcription initiation genetic 1 1 1 Positive Genetic
HST1 YOL068C NAD(+)-dependent histone deacetylase genetic 1 1 1 Positive Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
LSM4 YER112W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
MAL12 YGR292W Maltase (alpha-D-glucosidase) genetic 1 1 1 Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Negative Genetic
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Negative Genetic
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase genetic 1 1 1 Dosage Rescue
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Positive Genetic
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 1 1 1 Positive Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Negative Genetic
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 1 1 1 Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
NHP6B YBR089C-A High-mobility group (HMG) protein genetic 1 1 1 Dosage Rescue
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Positive Genetic
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Growth Defect
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Positive Genetic
HTA1 YDR225W Histone H2A genetic 1 1 1 Negative Genetic
PRP28 YDR243C Pre-mRNA splicing factor genetic 1 1 1 Positive Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Negative Genetic
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase genetic 1 1 1 Negative Genetic
RAD23 YEL037C Protein with ubiquitin-like N terminus genetic 1 1 1 Positive Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
ROX3 YBL093C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Suppression
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Synthetic Lethality
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 1 1 1 Negative Genetic
RPC53 YDL150W RNA polymerase III subunit C53 genetic 1 1 1 Negative Genetic
RRI1 YDL216C Catalytic subunit of the COP9 signalosome (CSN) complex genetic 1 1 1 Positive Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Positive Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Positive Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Positive Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Lethality
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Synthetic Lethality
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
SEC17 YBL050W Alpha-SNAP cochaperone genetic 1 1 1 Positive Genetic
SIP2 YGL208W One of three alternate beta subunits of the Snf1 kinase complex genetic 1 1 1 Positive Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
SPT15 YER148W TATA-binding protein (TBP) physical 1 1 1 Affinity Capture-MS
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
SRB6 YBR253W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Suppression
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Positive Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Positive Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Synthetic Growth Defect
FUN30 YAL019W Snf2p family member with ATP-dependent chromatin remodeling activity genetic 1 1 1 Positive Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
SPP1 YPL138C Subunit of COMPASS (Set1C) genetic 1 1 1 Negative Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Growth Defect
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen genetic 1 1 1 Negative Genetic
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes genetic 1 1 1 Negative Genetic
AKL1 YBR059C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
ARF1 YDL192W ADP-ribosylation factor genetic 1 1 1 Positive Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Positive Genetic
GSP2 YOR185C GTP binding protein (mammalian Ranp homolog) genetic 1 1 1 Negative Genetic
FAA4 YMR246W Long chain fatty acyl-CoA synthetase genetic 1 1 1 Positive Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Negative Genetic
FDO1 YMR144W Protein involved in directionality of mating type switching genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) genetic 1 1 1 Negative Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Positive Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Synthetic Growth Defect
ARP10 YDR106W Component of the dynactin complex genetic 1 1 1 Negative Genetic
FAR1 YJL157C CDK inhibitor and nuclear anchor genetic 1 1 1 Negative Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
RAD55 YDR076W Protein that stimulates strand exchange genetic 1 1 1 Synthetic Lethality
CYC8 YBR112C General transcriptional co-repressor genetic 1 1 1 Positive Genetic
DBF20 YPR111W Ser/Thr kinase involved in late nuclear division genetic 1 1 1 Positive Genetic
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 1 1 1 Negative Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 1 1 1 Negative Genetic
ELA1 YNL230C Elongin A genetic 1 1 1 Positive Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Positive Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
DOP1 YDR141C Protein involved in vesicular transport at trans-Golgi network (TGN) genetic 1 1 1 Negative Genetic
GAC1 YOR178C Regulatory subunit for Glc7p type-1 protein phosphatase (PP1) genetic 1 1 1 Negative Genetic
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-MS
GID8 YMR135C Subunit of GID Complex, binds strongly to central component Vid30p genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Positive Genetic
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV physical 1 1 1 PCA
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Positive Genetic
RAD18 YCR066W E3 ubiquitin ligase genetic 1 1 1 Synthetic Lethality
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Phenotypic Suppression
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Negative Genetic
KIN2 YLR096W S/T protein kinase physical 1 1 1 Affinity Capture-MS
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 1 1 1 Positive Genetic
AIP5 YFR016C Protein that positively regulates actin assembly genetic 1 1 1 Positive Genetic
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Synthetic Growth Defect
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Positive Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Lethality
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Synthetic Lethality
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) genetic 1 1 1 Dosage Growth Defect
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 1 1 1 Synthetic Lethality
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 1 1 1 Positive Genetic
FPK1 YNR047W Ser/Thr protein kinase genetic 1 1 1 Positive Genetic
NOP13 YNL175C Nucleolar protein found in preribosomal complexes genetic 1 1 1 Negative Genetic
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 1 1 1 Negative Genetic
PCL6 YER059W Pho85p cyclin of the Pho80p subfamily genetic 1 1 1 Positive Genetic
EPT1 YHR123W sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase genetic 1 1 1 Negative Genetic
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 1 1 1 Negative Genetic
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Synthetic Lethality
AIR1 YIL079C Zinc knuckle protein genetic 1 1 1 Positive Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases physical 1 1 1 Biochemical Activity
GTO1 YGR154C Omega-class glutathione transferase genetic 1 1 1 Positive Genetic
LOS1 YKL205W Nuclear pore protein genetic 1 1 1 Negative Genetic
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 1 1 1 Negative Genetic
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 1 1 1 Synthetic Growth Defect
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Positive Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Positive Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Negative Genetic
ARO9 YHR137W Aromatic aminotransferase II genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
CRC1 YOR100C Mitochondrial inner membrane carnitine transporter genetic 1 1 1 Negative Genetic
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Positive Genetic
SIR1 YKR101W Protein involved in silencing at mating-type loci HML and HMR genetic 1 1 1 Synthetic Rescue
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Positive Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Negative Genetic
CLN3 YAL040C G1 cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-Western
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Synthetic Lethality
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Synthetic Lethality
FIG1 YBR040W Integral membrane protein required for efficient mating genetic 1 1 1 Negative Genetic
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
MRP8 YKL142W Protein of unknown function genetic 1 1 1 Negative Genetic
MSN5 YDR335W Karyopherin physical 1 1 1 Two-hybrid
HAA1 YPR008W Transcriptional activator involved in adaptation to weak acid stress genetic 1 1 1 Positive Genetic
PCL8 YPL219W Cyclin genetic 1 1 1 Positive Genetic
RPS26A YGL189C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SOR1 YJR159W Sorbitol dehydrogenase genetic 1 1 1 Negative Genetic
MVP1 YMR004W Protein required for sorting proteins to the vacuole genetic 1 1 1 Negative Genetic
DLS1 YJL065C Subunit of ISW2/yCHRAC chromatin accessibility complex genetic 1 1 1 Negative Genetic
LDB17 YDL146W Protein involved in the regulation of endocytosis genetic 1 1 1 Negative Genetic
CNL1 YDR357C Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Positive Genetic
PEF1 YGR058W Penta-EF-hand protein genetic 1 1 1 Positive Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Positive Genetic
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
DOC1 YGL240W Processivity factor genetic 1 1 1 Negative Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Positive Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
NHP6A YPR052C High-mobility group (HMG) protein genetic 1 1 1 Dosage Rescue
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Synthetic Growth Defect
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 1 1 1 Positive Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) genetic 1 1 1 Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF8 YML114C TFIID subunit (65 kDa) physical 1 1 1 Affinity Capture-MS
TAF7 YMR227C TFIID subunit (67 kDa) physical 1 1 1 Affinity Capture-MS
YOL131W YOL131W Putative protein of unknown function physical 1 1 1 Two-hybrid
TRR1 YDR353W Cytoplasmic thioredoxin reductase genetic 1 1 1 Synthetic Rescue
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Negative Genetic
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) genetic 1 1 1 Phenotypic Enhancement
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) genetic 1 1 1 Negative Genetic
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Positive Genetic
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 1 1 1 Positive Genetic
THR1 YHR025W Homoserine kinase genetic 1 1 1 Negative Genetic
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Positive Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Positive Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 1 1 1 Negative Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Positive Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Positive Genetic
VTC1 YER072W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Negative Genetic
YPI1 YFR003C Regulatory subunit of the type I protein phosphatase (PP1) Glc7p genetic 1 1 1 Positive Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Positive Genetic
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Positive Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Synthetic Lethality
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 1 1 1 Synthetic Growth Defect
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes genetic 1 1 1 Synthetic Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Negative Genetic
USV1 YPL230W Putative transcription factor containing a C2H2 zinc finger genetic 1 1 1 Negative Genetic
XBP1 YIL101C Transcriptional repressor genetic 1 1 1 Negative Genetic
ZAP1 YJL056C Zinc-regulated transcription factor genetic 1 1 1 Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Negative Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Positive Genetic
THI2 YBR240C Transcriptional activator of thiamine biosynthetic genes genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
TRS31 YDR472W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Positive Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Positive Genetic
TFB4 YPR056W Subunit of TFIIH complex genetic 1 1 1 Positive Genetic
YBR090C YBR090C Putative protein of unknown function genetic 1 1 1 Positive Genetic
YBP2 YGL060W Central kinetochore associated protein genetic 1 1 1 Positive Genetic
TPO2 YGR138C Polyamine transporter of the major facilitator superfamily genetic 1 1 1 Positive Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Positive Genetic
YHR112C YHR112C Protein of unknown function genetic 1 1 1 Positive Genetic
TED1 YIL039W GPI-glycan remodelase genetic 1 1 1 Positive Genetic
YJR015W YJR015W Putative protein of unknown function genetic 1 1 1 Positive Genetic
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 1 1 1 Positive Genetic
YKL162C YKL162C Putative protein of unknown function genetic 1 1 1 Positive Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Positive Genetic
YNR071C YNR071C Putative aldose 1-epimerase genetic 1 1 1 Positive Genetic
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
URB2 YJR041C Protein required for normal metabolism of the rRNA primary transcript genetic 1 1 1 Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
YCL001W-B YCL001W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
YDR042C YDR042C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TSA2 YDR453C Stress inducible cytoplasmic thioredoxin peroxidase genetic 1 1 1 Negative Genetic
YER079W YER079W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YER158C YER158C Protein of unknown function genetic 1 1 1 Negative Genetic
YGR130C YGR130C Component of the eisosome with unknown function genetic 1 1 1 Negative Genetic
YGR210C YGR210C Putative protein of unknown function genetic 1 1 1 Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Negative Genetic
TAX4 YJL083W EH domain-containing protein genetic 1 1 1 Negative Genetic
YJR011C YJR011C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Negative Genetic
YLR363W-A YLR363W-A Protein of unknown function genetic 1 1 1 Negative Genetic
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Negative Genetic
YMR196W YMR196W Putative protein of unknown function genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
YNL194C YNL194C Integral membrane protein genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Negative Genetic
YOR072W-B YOR072W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif genetic 1 1 1 Negative Genetic
YPL113C YPL113C Glyoxylate reductase genetic 1 1 1 Negative Genetic
TEF1 YPR080W Translational elongation factor EF-1 alpha genetic 1 1 1 Negative Genetic
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Synthetic Growth Defect
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Positive Genetic
PLC1 YPL268W Phospholipase C genetic 1 1 1 Positive Genetic
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start genetic 1 1 1 Negative Genetic
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Lethality
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
IOC4 YMR044W Member of a complex (Isw1b) with Isw1p and Ioc2p genetic 1 1 1 Negative Genetic
MYO5 YMR109W One of two type I myosin motors genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Positive Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Negative Genetic
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Negative Genetic
MGM1 YOR211C Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p genetic 1 1 1 Negative Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Positive Genetic
DPH2 YKL191W Protein required for synthesis of diphthamide genetic 1 1 1 Negative Genetic
DPH1 YIL103W Protein required for synthesis of diphthamide genetic 1 1 1 Positive Genetic
IQG1 YPL242C Actin filament binding protein that enhances actin ring formation genetic 1 1 1 Positive Genetic
PHO2 YDL106C Homeobox transcription factor genetic 1 1 1 Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Phenotypic Suppression
SSO1 YPL232W Plasma membrane t-SNARE genetic 1 1 1 Negative Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Positive Genetic
HAP4 YKL109W Transcription factor genetic 1 1 1 Phenotypic Suppression
RRN11 YML043C Component of the core factor (CF) rDNA transcription factor complex genetic 1 1 1 Negative Genetic
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family genetic 1 1 1 Synthetic Lethality
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p physical 1 1 1 Affinity Capture-MS
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Synthetic Growth Defect
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 1 1 1 Synthetic Lethality
BNR1 YIL159W Formin genetic 1 1 1 Positive Genetic
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Synthetic Lethality
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Negative Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Positive Genetic
ESC1 YMR219W Protein involved in telomeric silencing genetic 1 1 1 Negative Genetic
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 1 1 1 Negative Genetic
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 1 1 1 Negative Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 1 1 1 Affinity Capture-MS
RLM1 YPL089C MADS-box transcription factor genetic 1 1 1 Phenotypic Enhancement
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
SIP3 YNL257C Putative sterol transfer protein genetic 1 1 1 Negative Genetic
ORC5 YNL261W Subunit of the origin recognition complex (ORC) physical 1 1 1 Two-hybrid
DFG5 YMR238W Putative mannosidase genetic 1 1 1 Positive Genetic
MSB3 YNL293W Rab GTPase-activating protein genetic 1 1 1 Positive Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Synthetic Growth Defect
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 1 1 1 Positive Genetic
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
COX17 YLL009C Copper metallochaperone that transfers copper to Sco1p and Cox11p genetic 1 1 1 Negative Genetic
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Positive Genetic
REC8 YPR007C Meiosis-specific component of the sister chromatid cohesion complex genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Positive Genetic
MNN14 YJR061W Protein required for N-glycan mannosylphosphorylation genetic 1 1 1 Negative Genetic
KAP120 YPL125W Karyopherin responsible for the nuclear import of Rpf1p physical 1 1 1 Affinity Capture-Western
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Positive Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Negative Genetic
PIN3 YPR154W Negative regulator of actin nucleation-promoting factor activity genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Synthetic Growth Defect
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
OSW7 YFR039C Protein involved in outer spore wall assembly genetic 1 1 1 Negative Genetic
KIP1 YBL063W Kinesin-related motor protein genetic 1 1 1 Synthetic Lethality
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Synthetic Lethality
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Negative Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
GDA1 YEL042W Guanosine diphosphatase located in the Golgi genetic 1 1 1 Positive Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 1 1 1 Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) genetic 1 1 1 Positive Genetic
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
HXK1 YFR053C Hexokinase isoenzyme 1 genetic 1 1 1 Negative Genetic
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Negative Genetic
PLM2 YDR501W Putative transcription factor, contains Forkhead Associated domain genetic 1 1 1 Positive Genetic
SLF1 YDR515W RNA binding protein that associates with polysomes genetic 1 1 1 Positive Genetic
ISD11 YER048W-A Cysteine desulfurase (Nfs1p) activator genetic 1 1 1 Positive Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Positive Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Positive Genetic
CUL3 YGR003W Ubiquitin-protein ligase genetic 1 1 1 Positive Genetic
CHA1 YCL064C Catabolic L-serine (L-threonine) deaminase genetic 1 1 1 Positive Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Negative Genetic
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 1 1 1 Synthetic Lethality
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Positive Genetic
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 1 1 1 Positive Genetic
MSA2 YKR077W Putative transcriptional activator physical 1 1 1 Affinity Capture-MS
SMT1 YJL147C Translational repressor of the mitochondrial ATP6/8 mRNA genetic 1 1 1 Negative Genetic
DSF1 YEL070W Mannitol dehydrogenase genetic 1 1 1 Positive Genetic
FMP41 YNL168C Putative protein of unknown function genetic 1 1 1 Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase genetic 1 1 1 Negative Genetic
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 1 1 1 Negative Genetic
JID1 YPR061C Probable Hsp40p co-chaperone genetic 1 1 1 Negative Genetic
STB3 YDR169C Ribosomal RNA processing element (RRPE)-binding protein genetic 1 1 1 Negative Genetic
BSC2 YDR275W Protein of unknown function involved in multidrug resistance genetic 1 1 1 Negative Genetic
SDD2 YMR074C Protein with homology to human PDCD5 genetic 1 1 1 Negative Genetic
ARO3 YDR035W 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase genetic 1 1 1 Negative Genetic
RPL24A YGL031C Ribosomal 60S subunit protein L24A genetic 1 1 1 Negative Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Negative Genetic
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 1 1 1 Positive Genetic
RPP2A YOL039W Ribosomal protein P2 alpha genetic 1 1 1 Negative Genetic
LDB7 YBL006C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
AIM29 YKR074W Protein of unknown function genetic 1 1 1 Negative Genetic
DFM1 YDR411C Endoplasmic reticulum (ER) localized protein genetic 1 1 1 Positive Genetic
MSN4 YKL062W Stress-responsive transcriptional activator genetic 1 1 1 Synthetic Growth Defect
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Negative Genetic
SSK22 YCR073C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Negative Genetic
SVF1 YDR346C Protein with a potential role in cell survival pathways genetic 1 1 1 Negative Genetic
OTU2 YHL013C Protein of unknown function genetic 1 1 1 Negative Genetic
PCK1 YKR097W Phosphoenolpyruvate carboxykinase genetic 1 1 1 Negative Genetic
SCD6 YPR129W Repressor of translation initiation genetic 1 1 1 Positive Genetic
SET4 YJL105W Chromatin-associated protein involved in control of stress response genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Positive Genetic
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Phenotypic Suppression
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
RQT4 YKR023W Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Positive Genetic
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 1 1 1 Positive Genetic
RPL15B YMR121C Ribosomal 60S subunit protein L15B genetic 1 1 1 Negative Genetic
OM14 YBR230C Mitochondrial outer membrane receptor for cytosolic ribosomes genetic 1 1 1 Positive Genetic
MRX18 YBR056W Putative glycoside hydrolase of the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
PSR2 YLR019W Putative plasma membrane phosphatase genetic 1 1 1 Positive Genetic
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
COM2 YER130C Transcription factor that binds IME1 Upstream Activation Signal (UAS) genetic 1 1 1 Positive Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Positive Genetic
NOP10 YHR072W-A Subunit of box H/ACA snoRNP complex genetic 1 1 1 Negative Genetic
MSA1 YOR066W Activator of G1-specific transcription factors MBF and SBF physical 1 1 1 Affinity Capture-MS
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
DUR3 YHL016C Plasma membrane transporter for both urea and polyamines genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Synthetic Growth Defect
HNT2 YDR305C Dinucleoside triphosphate hydrolase genetic 1 1 1 Positive Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis physical 1 1 1 PCA
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Negative Genetic
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Dosage Rescue
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Positive Genetic
DAT1 YML113W DNA binding protein that recognizes oligo(dA).oligo(dT) tracts genetic 1 1 1 Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 1 1 1 Positive Genetic
MET13 YGL125W Major isozyme of methylenetetrahydrofolate reductase genetic 1 1 1 Positive Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Synthetic Rescue
RPL12B YDR418W Ribosomal 60S subunit protein L12B genetic 1 1 1 Positive Genetic
GRS2 YPR081C Glycine-tRNA synthetase, not expressed under normal growth conditions genetic 1 1 1 Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 1 1 1 Positive Genetic
MPC1 YGL080W Highly conserved subunit of mitochondrial pyruvate carrier (MPC) genetic 1 1 1 Phenotypic Suppression
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Positive Genetic
MUM3 YOR298W Protein of unknown function involved in outer spore wall organization genetic 1 1 1 Positive Genetic
LEE1 YPL054W Zinc-finger protein of unknown function genetic 1 1 1 Negative Genetic
ERG8 YMR220W Phosphomevalonate kinase genetic 1 1 1 Positive Genetic
EGO2 YCR075W-A Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
HXT14 YNL318C Protein with similarity to hexose transporter family members genetic 1 1 1 Positive Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Negative Genetic
ATR2 YMR279C Putative boron transporter involved in boron efflux and resistance genetic 1 1 1 Positive Genetic
SEO1 YAL067C Putative permease genetic 1 1 1 Positive Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 1 1 1 Positive Genetic
SMF2 YHR050W Divalent metal ion transporter involved in manganese homeostasis genetic 1 1 1 Positive Genetic
OPT2 YPR194C Oligopeptide transporter genetic 1 1 1 Synthetic Lethality
ALK2 YBL009W Atypical protein kinase genetic 1 1 1 Positive Genetic
ROM1 YGR070W Guanine nucleotide exchange factor (GEF) for Rho1p genetic 1 1 1 Negative Genetic
ECT1 YGR007W Ethanolamine-phosphate cytidylyltransferase genetic 1 1 1 Negative Genetic
SVL3 YPL032C Protein of unknown function genetic 1 1 1 Negative Genetic
MNT3 YIL014W Alpha-1,3-mannosyltransferase genetic 1 1 1 Negative Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Negative Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Positive Genetic
ADF1 YCL058W-A Transcriptional repressor encoded by the FYV5 antisense strand genetic 1 1 1 Negative Genetic
SRL3 YKR091W Repressor of transcription at Start genetic 1 1 1 Phenotypic Suppression
MAY24 YPR153W Peripheral ER membrane protein genetic 1 1 1 Negative Genetic
KRE5 YOR336W Protein required for beta-1,6 glucan biosynthesis genetic 1 1 1 Positive Genetic
SSP2 YOR242C Sporulation specific protein that localizes to the spore wall genetic 1 1 1 Negative Genetic
SDL1 YIL167W Blocked reading frame otherwise encoding L-serine dehydratase genetic 1 1 1 Positive Genetic
SPO23 YBR250W Protein of unknown function genetic 1 1 1 Negative Genetic
SUT2 YPR009W Zn2Cys6 family transcription factor genetic 1 1 1 Negative Genetic
PGA1 YNL158W Essential component of GPI-mannosyltransferase II genetic 1 1 1 Positive Genetic
RMD6 YEL072W Protein required for sporulation genetic 1 1 1 Positive Genetic