Standard name Systematic name Name description Description
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase Cyclin (Bur2p)-dependent protein kinase; subunit of the CDK-cyclin BUR kinase complex with Bur2p; regulates Set2p-dependent H3K36 trimethylation; regulates transcriptional elongation through the phosphorylation of the carboxy-terminal domain (CTD) of Rpo21p; stimulates recruitment of the PAF complex through Spt5p CTD phosphorylation; recruits Spt6p to the CTD at the onset of transcription; regulates telomere elongation; regulated by Cak1p; similar to metazoan CDK9 proteins
Visualize the interactome of SGV1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.957 0.944 0.926

GFP localization & abundance

GFP localization GFP abundance
nucleus 2070

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SGV1 11 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
BUR2 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase physical 13 3 8 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 7 3 5 Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, Biochemical Activity
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 5 2 4 Synthetic Rescue, Synthetic Rescue, Negative Genetic, Negative Genetic, Synthetic Rescue
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 4 3 4 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement
BUR2 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase genetic 4 3 4 Dosage Rescue, Synthetic Growth Defect, Phenotypic Suppression, Dosage Rescue
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 4 3 4 Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Synthetic Rescue
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 4 3 3 Dosage Lethality, Dosage Lethality, Positive Genetic, Synthetic Rescue
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 4 2 1 Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 regulation 3 1 3 protein kinase assay evidence, protein kinase assay evidence, protein kinase assay evidence
CDC73 YLR418C Component of the Paf1p complex genetic 3 3 2 Synthetic Lethality, Positive Genetic, Negative Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 3 3 2 Synthetic Growth Defect, Synthetic Rescue, Negative Genetic
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 3 3 2 Dosage Rescue, Synthetic Growth Defect, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 3 2 2 Positive Genetic, Positive Genetic, Dosage Lethality
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 3 2 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
SUB1 YMR039C Transcriptional regulator genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Positive Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 2 2 2 Negative Genetic, Positive Genetic
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 2 2 Affinity Capture-MS, Co-purification
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
SPT6 YGR116W Nucleosome remodeling protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 2 2 2 Synthetic Rescue, Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 2 Negative Genetic, Positive Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 2 1 2 Biochemical Activity, Biochemical Activity
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 2 1 2 Negative Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 2 1 2 Negative Genetic, Negative Genetic
GBP2 YCL011C Poly(A+) RNA-binding protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 2 1 2 Negative Genetic, Negative Genetic
HRB1 YNL004W Poly(A+) RNA-binding protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 2 1 2 Negative Genetic, Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 2 2 1 Negative Genetic, Positive Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 2 2 1 Positive Genetic, Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 2 2 1 Positive Genetic, Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 2 2 1 Positive Genetic, Negative Genetic
CTO1 YCR015C Protein required for cold tolerance genetic 2 2 1 Positive Genetic, Negative Genetic
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 2 2 1 Dosage Rescue, Synthetic Lethality
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 2 2 1 Positive Genetic, Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 2 2 1 Positive Genetic, Negative Genetic
SWC3 YAL011W Protein of unknown function genetic 2 2 1 Positive Genetic, Negative Genetic
SNF3 YDL194W Plasma membrane low glucose sensor, regulates glucose transport genetic 2 2 1 Positive Genetic, Negative Genetic
SNX41 YDR425W Sorting nexin genetic 2 2 1 Positive Genetic, Negative Genetic
XDJ1 YLR090W Chaperone with a role in facilitating mitochondrial protein import genetic 2 2 1 Positive Genetic, Negative Genetic
YVC1 YOR087W Vacuolar cation channel genetic 2 2 1 Positive Genetic, Negative Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 2 2 1 Positive Genetic, Negative Genetic
YLR154C-H YLR154C-H Putative protein of unknown function genetic 2 2 1 Positive Genetic, Negative Genetic
TEN1 YLR010C Protein that regulates telomeric length genetic 2 2 1 Synthetic Growth Defect, Dosage Rescue
STN1 YDR082W Telomere end-binding and capping protein genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
HEM13 YDR044W Coproporphyrinogen III oxidase genetic 2 2 1 Positive Genetic, Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 2 1 Positive Genetic, Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 2 2 1 Positive Genetic, Negative Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 2 2 1 Positive Genetic, Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 2 2 1 Positive Genetic, Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 2 2 1 Positive Genetic, Negative Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 2 2 1 Positive Genetic, Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 2 2 1 Positive Genetic, Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 2 2 1 Positive Genetic, Negative Genetic
ARO8 YGL202W Aromatic aminotransferase I genetic 2 2 1 Positive Genetic, Negative Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 2 2 1 Positive Genetic, Negative Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 2 1 1 Negative Genetic, Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 2 1 1 Negative Genetic, Negative Genetic
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 2 1 1 Negative Genetic, Negative Genetic
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 2 1 1 Negative Genetic, Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 2 1 1 Negative Genetic, Negative Genetic
MAK21 YDR060W Constituent of 66S pre-ribosomal particles genetic 2 1 1 Negative Genetic, Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 2 1 1 Positive Genetic, Positive Genetic
RPB5 YBR154C RNA polymerase subunit ABC27 genetic 2 1 1 Negative Genetic, Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
AAR2 YBL074C Component of the U5 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex genetic 2 1 1 Negative Genetic, Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 2 1 1 Negative Genetic, Negative Genetic
HHF1 YBR009C Histone H4 genetic 2 1 1 Negative Genetic, Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 2 1 1 Negative Genetic, Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 2 1 1 Negative Genetic, Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 2 1 1 Positive Genetic, Positive Genetic
CMD1 YBR109C Calmodulin genetic 2 1 1 Negative Genetic, Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 2 1 1 Negative Genetic, Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 2 1 1 Negative Genetic, Negative Genetic
PRP28 YDR243C Pre-mRNA splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
PRP31 YGR091W Splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
PRP21 YJL203W Subunit of the SF3a splicing factor complex genetic 2 1 1 Negative Genetic, Negative Genetic
RNA14 YMR061W Component of the cleavage and polyadenylation factor I (CF I) genetic 2 1 1 Negative Genetic, Negative Genetic
RPB8 YOR224C RNA polymerase subunit ABC14.5 genetic 2 1 1 Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Negative Genetic, Negative Genetic
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Negative Genetic, Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 2 1 1 Positive Genetic, Positive Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 2 1 1 Negative Genetic, Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 2 1 1 Negative Genetic, Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 2 1 1 Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Negative Genetic, Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 2 1 1 Negative Genetic, Negative Genetic
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
PRP11 YDL043C Subunit of the SF3a splicing factor complex genetic 2 1 1 Negative Genetic, Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 2 1 1 Positive Genetic, Positive Genetic
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export genetic 2 1 1 Negative Genetic, Negative Genetic
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
YRB1 YDR002W Ran GTPase binding protein genetic 2 1 1 Negative Genetic, Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 2 1 1 Negative Genetic, Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 2 1 1 Negative Genetic, Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 2 1 1 Negative Genetic, Negative Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 2 1 1 Negative Genetic, Negative Genetic
TAH11 YJR046W DNA replication licensing factor genetic 2 1 1 Negative Genetic, Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 2 1 1 Negative Genetic, Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 2 1 1 Negative Genetic, Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 2 1 1 Negative Genetic, Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 2 1 1 Negative Genetic, Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 2 1 1 Negative Genetic, Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 2 1 1 Negative Genetic, Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 2 1 1 Negative Genetic, Negative Genetic
YGR283C YGR283C Putative methyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 2 1 1 Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 1 Negative Genetic, Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 2 1 1 Negative Genetic, Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 2 1 1 Negative Genetic, Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 2 1 1 Negative Genetic, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 2 1 1 Negative Genetic, Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 2 1 1 Negative Genetic, Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 2 1 1 Negative Genetic, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 2 1 1 Negative Genetic, Negative Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 1 Negative Genetic, Negative Genetic
YLF2 YHL014C Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
SWD2 YKL018W Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 2 1 1 Negative Genetic, Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 1 1 Negative Genetic, Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 2 1 1 Negative Genetic, Negative Genetic
KOG1 YHR186C Subunit of TORC1 genetic 2 1 1 Negative Genetic, Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 2 1 1 Negative Genetic, Negative Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 2 1 1 Negative Genetic, Negative Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 2 1 1 Negative Genetic, Negative Genetic
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 2 1 1 Negative Genetic, Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 2 1 1 Negative Genetic, Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 2 1 1 Negative Genetic, Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 2 1 1 Negative Genetic, Negative Genetic
MSG5 YNL053W Dual-specificity protein phosphatase genetic 2 1 1 Negative Genetic, Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 2 1 1 Negative Genetic, Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 2 1 1 Positive Genetic, Positive Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 1 Negative Genetic, Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 1 1 Negative Genetic, Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 2 1 1 Negative Genetic, Negative Genetic
PRP5 YBR237W RNA helicase in the DEAD-box family genetic 2 1 1 Negative Genetic, Negative Genetic
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 2 1 1 Negative Genetic, Negative Genetic
LAA2 YBL010C Clathrin adaptor (adaptin) accessory protein genetic 2 1 1 Negative Genetic, Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 2 1 1 Negative Genetic, Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 2 1 1 Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 2 1 1 Negative Genetic, Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 2 1 1 Negative Genetic, Negative Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase genetic 2 1 1 Negative Genetic, Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 2 1 1 Positive Genetic, Positive Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 2 1 1 Negative Genetic, Negative Genetic
BET1 YIL004C Type II membrane protein required for vesicular transport genetic 2 1 1 Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 2 1 1 Negative Genetic, Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 2 1 1 Negative Genetic, Negative Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 2 1 1 Negative Genetic, Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 1 1 Negative Genetic, Negative Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
PET494 YNR045W Mitochondrial translational activator specific for the COX3 mRNA genetic 2 1 1 Negative Genetic, Negative Genetic
ASG1 YIL130W Zinc cluster protein proposed to be a transcriptional regulator genetic 2 1 1 Negative Genetic, Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 2 1 1 Positive Genetic, Positive Genetic
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 genetic 2 1 1 Negative Genetic, Negative Genetic
AIM22 YJL046W Lipoate-protein ligase genetic 2 1 1 Negative Genetic, Negative Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 2 1 1 Negative Genetic, Negative Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 2 1 1 Negative Genetic, Negative Genetic
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 2 1 1 Negative Genetic, Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 2 1 1 Negative Genetic, Negative Genetic
CYT1 YOR065W Cytochrome c1 genetic 2 1 1 Negative Genetic, Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 2 1 1 Negative Genetic, Negative Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 2 1 1 Negative Genetic, Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Synthetic Rescue
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Synthetic Lethality
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Negative Genetic
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs genetic 1 1 1 Positive Genetic
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Synthetic Lethality
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Positive Genetic
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
BFR2 YDR299W Component of the SSU and 90S preribosomes physical 1 1 1 Affinity Capture-MS
ENP2 YGR145W Component of the SSU genetic 1 1 1 Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Positive Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
BRX1 YOL077C Nucleolar protein physical 1 1 1 Affinity Capture-MS
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing physical 1 1 1 Affinity Capture-MS
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing genetic 1 1 1 Positive Genetic
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function genetic 1 1 1 Negative Genetic
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase genetic 1 1 1 Positive Genetic
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Positive Genetic
RPL38 YLR325C Ribosomal 60S subunit protein L38 genetic 1 1 1 Negative Genetic
IPI1 YHR085W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Negative Genetic
GCD6 YDR211W Catalytic epsilon subunit of the translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
AMN1 YBR158W Modulator of cell separation and mitotic exit genetic 1 1 1 Positive Genetic
AXL2 YIL140W Integral plasma membrane protein genetic 1 1 1 Positive Genetic
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Positive Genetic
PFK27 YOL136C 6-phosphofructo-2-kinase genetic 1 1 1 Negative Genetic
RGT2 YDL138W Plasma membrane high glucose sensor that regulates glucose transport genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
PRP45 YAL032C Protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
KRE29 YER038C Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 1 1 1 Affinity Capture-MS
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-MS
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Negative Genetic
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
ALB1 YJL122W Shuttling pre-60S factor genetic 1 1 1 Negative Genetic
HCA4 YJL033W DEAD box RNA helicase physical 1 1 1 Affinity Capture-MS
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase physical 1 1 1 Affinity Capture-MS
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PRP3 YDR473C Splicing factor genetic 1 1 1 Negative Genetic
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 1 1 1 Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Positive Genetic
NPL3 YDR432W RNA-binding protein physical 1 1 1 Affinity Capture-MS
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
RPC17 YJL011C RNA polymerase III subunit C17 genetic 1 1 1 Negative Genetic
RPC19 YNL113W RNA polymerase subunit AC19 physical 1 1 1 Affinity Capture-MS
RPC31 YNL151C RNA polymerase III subunit C31 genetic 1 1 1 Negative Genetic
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPA49 YNL248C RNA polymerase I subunit A49 physical 1 1 1 Affinity Capture-MS
RPA43 YOR340C RNA polymerase I subunit A43 genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 1 1 1 Affinity Capture-Western
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Positive Genetic
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Negative Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
PRP40 YKL012W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing physical 1 1 1 Affinity Capture-MS
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 1 1 1 Affinity Capture-MS
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 1 1 1 Positive Genetic
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Positive Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Positive Genetic
RLI1 YDR091C Essential Fe-S protein genetic 1 1 1 Negative Genetic
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 1 1 1 Negative Genetic
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF genetic 1 1 1 Positive Genetic
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme genetic 1 1 1 Negative Genetic
APC2 YLR127C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 1 1 1 Positive Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Negative Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Positive Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Positive Genetic
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Positive Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
ERG26 YGL001C C-3 sterol dehydrogenase genetic 1 1 1 Negative Genetic
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Positive Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Positive Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Negative Genetic
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome genetic 1 1 1 Negative Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
EMG1 YLR186W Methyltransferase for rRNA genetic 1 1 1 Negative Genetic
FAP1 YNL023C Protein that binds to Fpr1p genetic 1 1 1 Positive Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Positive Genetic
HRP1 YOL123W Subunit of cleavage factor I genetic 1 1 1 Negative Genetic
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 1 1 1 Positive Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
KIN3 YAR018C Nonessential serine/threonine protein kinase genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Positive Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Positive Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Positive Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) genetic 1 1 1 Positive Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Negative Genetic
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Positive Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Positive Genetic
MRM1 YOR201C Ribose methyltransferase genetic 1 1 1 Negative Genetic
BUD3 YCL014W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 1 1 1 Affinity Capture-MS
ATG26 YLR189C UDP-glucose:sterol glucosyltransferase genetic 1 1 1 Negative Genetic
MRP49 YKL167C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Synthetic Rescue
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Synthetic Rescue
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair physical 1 1 1 Affinity Capture-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Positive Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
NPL4 YBR170C Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase genetic 1 1 1 Negative Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member physical 1 1 1 Affinity Capture-MS
PBP2 YBR233W RNA binding protein genetic 1 1 1 Positive Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Negative Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Positive Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
MRPL38 YKL170W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
PAA1 YDR071C Polyamine acetyltransferase genetic 1 1 1 Negative Genetic
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon physical 1 1 1 Biochemical Activity
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Negative Genetic
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
NAB6 YML117W Putative RNA-binding protein genetic 1 1 1 Negative Genetic
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome genetic 1 1 1 Positive Genetic
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase genetic 1 1 1 Negative Genetic
NOP14 YDL148C Nucleolar protein physical 1 1 1 Affinity Capture-MS
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
ESF2 YNR054C Essential nucleolar protein involved in pre-18S rRNA processing genetic 1 1 1 Negative Genetic
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes genetic 1 1 1 Negative Genetic
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p genetic 1 1 1 Positive Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Positive Genetic
RAD52 YML032C Protein involved in homologous recombination physical 1 1 1 Affinity Capture-MS
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Synthetic Growth Defect
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Synthetic Rescue
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Positive Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPB11 YOL005C RNA polymerase II subunit B12.5 genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Synthetic Rescue
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Negative Genetic
PCI8 YIL071C Possible shared subunit of Cop9 signalosome (CSN) and eIF3 genetic 1 1 1 Negative Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Positive Genetic
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 1 1 1 Negative Genetic
SGN1 YIR001C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-MS
SGN1 YIR001C Cytoplasmic RNA-binding protein genetic 1 1 1 Negative Genetic
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Negative Genetic
ABF2 YMR072W Mitochondrial DNA-binding protein physical 1 1 1 Affinity Capture-MS
RXT3 YDL076C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
ECM25 YJL201W Endocytic site protein required for stress-induced cell elongation genetic 1 1 1 Negative Genetic
INP52 YNL106C Polyphosphatidylinositol phosphatase physical 1 1 1 Affinity Capture-MS
BSP1 YPR171W Adapter that links synaptojanins to the cortical actin cytoskeleton physical 1 1 1 Affinity Capture-MS
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
SEC17 YBL050W Alpha-SNAP cochaperone genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
PRP42 YDR235W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Positive Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Positive Genetic
MSH4 YFL003C Protein involved in meiotic recombination genetic 1 1 1 Negative Genetic
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex genetic 1 1 1 Negative Genetic
SPC110 YDR356W Inner plaque spindle pole body (SPB) component physical 1 1 1 Co-purification
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Positive Genetic
YAR010C YAR010C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
SPB1 YCL054W AdoMet-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
TSR1 YDL060W Protein required for processing of 20S pre-rRNA in the cytoplasm physical 1 1 1 Affinity Capture-MS
TMA64 YDR117C Protein of unknown function that associates with ribosomes physical 1 1 1 Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Positive Genetic
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-MS
STE20 YHL007C Cdc42p-activated signal transducing kinase physical 1 1 1 Biochemical Activity
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
YHP1 YDR451C Homeobox transcriptional repressor genetic 1 1 1 Negative Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Synthetic Growth Defect
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
TTI2 YJR136C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
SPO7 YAL009W Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
UTH1 YKR042W Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Positive Genetic
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
YPI1 YFR003C Regulatory subunit of the type I protein phosphatase (PP1) Glc7p genetic 1 1 1 Positive Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Positive Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Positive Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Positive Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Positive Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 1 1 1 Positive Genetic
YBL081W YBL081W Non-essential protein of unknown function genetic 1 1 1 Positive Genetic
UGA2 YBR006W Succinate semialdehyde dehydrogenase genetic 1 1 1 Positive Genetic
ZTA1 YBR046C NADPH-dependent quinone reductase genetic 1 1 1 Positive Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 1 1 1 Positive Genetic
TBS1 YBR150C Protein of unknown function genetic 1 1 1 Positive Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
UBX3 YDL091C Clathrin-coated vesicle component, regulator of endocytosis genetic 1 1 1 Positive Genetic
YDL144C YDL144C Protein of unknown function genetic 1 1 1 Positive Genetic
YDL180W YDL180W Putative protein of unknown function genetic 1 1 1 Positive Genetic
TGL2 YDR058C Triacylglycerol lipase that is localized to the mitochondria genetic 1 1 1 Positive Genetic
YDR131C YDR131C F-box protein subunit of SCF ubiquitin ligase complex genetic 1 1 1 Positive Genetic
YDR248C YDR248C Putative gluconokinase genetic 1 1 1 Positive Genetic
SSF2 YDR312W Protein required for ribosomal large subunit maturation genetic 1 1 1 Positive Genetic
YPS7 YDR349C Putative GPI-anchored aspartic protease genetic 1 1 1 Positive Genetic
YGR130C YGR130C Component of the eisosome with unknown function genetic 1 1 1 Positive Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
SOL3 YHR163W 6-phosphogluconolactonase genetic 1 1 1 Positive Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Positive Genetic
TMA108 YIL137C Ribosome-associated, nascent chain binding factor genetic 1 1 1 Positive Genetic
YIR016W YIR016W Putative protein of unknown function genetic 1 1 1 Positive Genetic
YJR149W YJR149W Putative protein of unknown function genetic 1 1 1 Positive Genetic
TMA19 YKL056C Protein that associates with ribosomes genetic 1 1 1 Positive Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 1 1 1 Positive Genetic
YKL075C YKL075C Putative protein of unknown function genetic 1 1 1 Positive Genetic
YLR053C YLR053C Putative protein of unknown function genetic 1 1 1 Positive Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Positive Genetic
SPE4 YLR146C Spermine synthase genetic 1 1 1 Positive Genetic
YLR415C YLR415C Putative protein of unknown function genetic 1 1 1 Positive Genetic
YMR253C YMR253C Putative protein of unknown function genetic 1 1 1 Positive Genetic
YMR317W YMR317W Putative protein of unknown function genetic 1 1 1 Positive Genetic
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Positive Genetic
URA7 YBL039C Major CTP synthase isozyme (see also URA8) genetic 1 1 1 Positive Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Positive Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Positive Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Positive Genetic
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Positive Genetic
SUC2 YIL162W Invertase genetic 1 1 1 Positive Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Positive Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Positive Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Positive Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 1 1 1 Positive Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Positive Genetic
YHL042W YHL042W Endoplasmic reticulum protein genetic 1 1 1 Positive Genetic
YHR127W YHR127W Protein of unknown function genetic 1 1 1 Positive Genetic
YKL096C-B YKL096C-B Putative protein of unknown function genetic 1 1 1 Positive Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Positive Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Negative Genetic
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
SRB4 YER022W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
UTP7 YER082C Nucleolar protein genetic 1 1 1 Negative Genetic
SUA5 YGL169W Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
TFG1 YGR186W TFIIF (Transcription Factor II) largest subunit genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Negative Genetic
UTP25 YIL091C Nucleolar protein genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
URB2 YJR041C Protein required for normal metabolism of the rRNA primary transcript genetic 1 1 1 Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
UTP21 YLR409C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Negative Genetic
SPP382 YLR424W Essential protein that forms a dimer with Ntr2p genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
TRS130 YMR218C Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing genetic 1 1 1 Negative Genetic
THI80 YOR143C Thiamine pyrophosphokinase genetic 1 1 1 Negative Genetic
SME1 YOR159C Core Sm protein Sm E genetic 1 1 1 Negative Genetic
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
SRP68 YPL243W Core component of the signal recognition particle (SRP) complex genetic 1 1 1 Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
SYF1 YDR416W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Negative Genetic
STT4 YLR305C Phosphatidylinositol-4-kinase genetic 1 1 1 Negative Genetic
SMC6 YLR383W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 1 1 1 Negative Genetic
ZPR1 YGR211W Essential protein with two zinc fingers genetic 1 1 1 Negative Genetic
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 1 1 1 Negative Genetic
URA6 YKL024C Uridylate kinase genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
YBR016W YBR016W Tail-anchored plasma membrane protein with a conserved CYSTM module genetic 1 1 1 Negative Genetic
TDP1 YBR223C Tyrosyl-DNA phosphodiesterase I genetic 1 1 1 Negative Genetic
SHM1 YBR263W Mitochondrial serine hydroxymethyltransferase genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
UPC2 YDR213W Sterol regulatory element binding protein genetic 1 1 1 Negative Genetic
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Negative Genetic
STL1 YDR536W Glycerol proton symporter of the plasma membrane genetic 1 1 1 Negative Genetic
TPA1 YER049W Prolyl hydroxylase genetic 1 1 1 Negative Genetic
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Negative Genetic
YER152C YER152C Protein with 2-aminoadipate transaminase activity genetic 1 1 1 Negative Genetic
YGL036W YGL036W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR026W YGR026W Putative protein of unknown function genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
TIM13 YGR181W Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
VHS2 YIL135C Regulator of septin dynamics genetic 1 1 1 Negative Genetic
YIL161W YIL161W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor genetic 1 1 1 Negative Genetic
YIR042C YIR042C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SNX4 YJL036W Sorting nexin genetic 1 1 1 Negative Genetic
YJR015W YJR015W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TES1 YJR019C Peroxisomal acyl-CoA thioesterase genetic 1 1 1 Negative Genetic
TCD2 YKL027W tRNA threonylcarbamoyladenosine dehydratase genetic 1 1 1 Negative Genetic
YKL063C YKL063C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 1 1 1 Negative Genetic
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator genetic 1 1 1 Negative Genetic
YLR046C YLR046C Putative membrane protein genetic 1 1 1 Negative Genetic
SUL2 YLR092W High affinity sulfate permease genetic 1 1 1 Negative Genetic
TML25 YLR118C Acyl-protein thioesterase responsible for depalmitoylation of Gpa1p genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Negative Genetic
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
TOM7 YNL070W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Negative Genetic
TOS7 YOL019W Protein involved in secretion and cell wall organization genetic 1 1 1 Negative Genetic
TRM11 YOL124C Catalytic subunit of adoMet-dependent tRNA methyltransferase complex genetic 1 1 1 Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Negative Genetic
WTM1 YOR230W Transcriptional modulator genetic 1 1 1 Negative Genetic
YOR289W YOR289W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
YIL054W YIL054W Protein of unknown function genetic 1 1 1 Negative Genetic
SOP4 YJL192C ER-membrane protein genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
YHM2 YMR241W Citrate and oxoglutarate carrier protein genetic 1 1 1 Negative Genetic
YMR295C YMR295C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 1 1 1 Negative Genetic
THI72 YOR192C Transporter of thiamine or related compound genetic 1 1 1 Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic
SIP1 YDR422C One of three alternate beta-subunits of the Snf1p kinase complex genetic 1 1 1 Negative Genetic
STP1 YDR463W Transcription factor genetic 1 1 1 Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Negative Genetic
XBP1 YIL101C Transcriptional repressor genetic 1 1 1 Negative Genetic
SIM1 YIL123W Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) genetic 1 1 1 Negative Genetic
YJL107C YJL107C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKL162C YKL162C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
VBA5 YKR105C Plasma membrane protein of the Major Facilitator Superfamily (MFS) genetic 1 1 1 Negative Genetic
VTA1 YLR181C Multivesicular body (MVB) protein genetic 1 1 1 Negative Genetic
URK1 YNR012W Uridine/cytidine kinase genetic 1 1 1 Negative Genetic
TUM1 YOR251C Rhodanese domain sulfur transferase genetic 1 1 1 Negative Genetic
TDA8 YAL064C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
YBL111C YBL111C Helicase-like protein encoded within the telomeric Y' element genetic 1 1 1 Negative Genetic
YBL112C YBL112C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YBR071W YBR071W Protein of unknown function found in the cytoplasm and bud neck genetic 1 1 1 Negative Genetic
TKL2 YBR117C Transketolase genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
YBR137W YBR137W Protein with a role in ER delivery of tail-anchored membrane proteins genetic 1 1 1 Negative Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
YBR184W YBR184W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YBR196C-B YBR196C-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
YCR023C YCR023C Vacuolar membrane protein of unknown function genetic 1 1 1 Negative Genetic
YCR024C-B YCR024C-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
YIH1 YCR059C Negative regulator of eIF2 kinase Gcn2p genetic 1 1 1 Negative Genetic
YDL057W YDL057W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SYO1 YDL063C Transport adaptor or symportin genetic 1 1 1 Negative Genetic
YDL159W-A YDL159W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YDL211C YDL211C Protein of unknown function genetic 1 1 1 Negative Genetic
YDL218W YDL218W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
SPG3 YDR504C Protein required for high temperature survival during stationary phase genetic 1 1 1 Negative Genetic
SPS1 YDR523C STE20-family GCKIII protein kinase genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Negative Genetic
YEL076C YEL076C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YEL077C YEL077C Helicase-like protein encoded within the telomeric Y' element genetic 1 1 1 Negative Genetic
YER039C-A YER039C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YEN1 YER041W Holliday junction resolvase genetic 1 1 1 Negative Genetic
YER076C YER076C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YIP4 YGL198W Protein that interacts with Rab GTPases genetic 1 1 1 Negative Genetic
VEL1 YGL258W Protein of unknown function genetic 1 1 1 Negative Genetic
SYF2 YGR129W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
YGR153W YGR153W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR240C-A YGR240C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR273C YGR273C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VHR1 YIL056W Transcriptional activator genetic 1 1 1 Negative Genetic
YIR018C-A YIR018C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YJL118W YJL118W Protein of unknown function genetic 1 1 1 Negative Genetic
SSH4 YKL124W Specificity factor required for Rsp5p-dependent ubiquitination genetic 1 1 1 Negative Genetic
SHB17 YKR043C Sedoheptulose bisphosphatase involved in riboneogenesis genetic 1 1 1 Negative Genetic
YKR045C YKR045C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TIS11 YLR136C mRNA-binding protein expressed during iron starvation genetic 1 1 1 Negative Genetic
THI7 YLR237W Plasma membrane transporter responsible for the uptake of thiamine genetic 1 1 1 Negative Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Negative Genetic
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TDA9 YML081W Transcription factor that regulates acetate production genetic 1 1 1 Negative Genetic
YML108W YML108W Protein of unknown function genetic 1 1 1 Negative Genetic
YMR155W YMR155W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YMR181C YMR181C Protein of unknown function genetic 1 1 1 Negative Genetic
YMR272W-B YMR272W-B Protein of unknown function genetic 1 1 1 Negative Genetic
SNO4 YMR322C Possible chaperone and cysteine protease genetic 1 1 1 Negative Genetic
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
SUN4 YNL066W Cell wall protein related to glucanases localized in birth scars genetic 1 1 1 Negative Genetic
YGP1 YNL160W Cell wall-related secretory glycoprotein genetic 1 1 1 Negative Genetic
YNL195C YNL195C Protein of unknown function genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
YNL277W-A YNL277W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 1 1 1 Negative Genetic
YPT11 YNL304W Rab GTPase genetic 1 1 1 Negative Genetic
SWM2 YNR004W Protein with a role in snRNA and snoRNA cap trimethylation genetic 1 1 1 Negative Genetic
YOL097W-A YOL097W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOL159C-A YOL159C-A Protein of unknown function genetic 1 1 1 Negative Genetic
YOL163W YOL163W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOL166W-A YOL166W-A Protein of unknown function genetic 1 1 1 Negative Genetic
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
YOR376W-A YOR376W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOR381W-A YOR381W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOR394C-A YOR394C-A Protein of unknown function genetic 1 1 1 Negative Genetic
YPL152W-A YPL152W-A Protein of unknown function genetic 1 1 1 Negative Genetic
YPL216W YPL216W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Phenotypic Enhancement
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
CRN1 YLR429W Coronin physical 1 1 1 Affinity Capture-MS
SEN54 YPL083C Subunit of the tRNA splicing endonuclease genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-MS
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles genetic 1 1 1 Negative Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Positive Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Positive Genetic
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Positive Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
DOT6 YER088C Protein involved in rRNA and ribosome biogenesis genetic 1 1 1 Negative Genetic
AIM17 YHL021C Protein of unknown function genetic 1 1 1 Positive Genetic
LSM12 YHR121W Protein of unknown function that may function in RNA processing physical 1 1 1 Affinity Capture-MS
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 1 1 1 Negative Genetic
LSP1 YPL004C Eisosome core component physical 1 1 1 Affinity Capture-MS
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane genetic 1 1 1 Negative Genetic
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor genetic 1 1 1 Negative Genetic
NGL2 YMR285C Protein involved in 5.8S rRNA processing genetic 1 1 1 Positive Genetic
ACH1 YBL015W Protein with CoA transferase activity genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Negative Genetic
ATG29 YPL166W Autophagy-specific protein genetic 1 1 1 Negative Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator genetic 1 1 1 Negative Genetic
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
SER1 YOR184W 3-phosphoserine aminotransferase genetic 1 1 1 Negative Genetic
BUB2 YMR055C Mitotic exit network regulator genetic 1 1 1 Negative Genetic
CNB1 YKL190W Calcineurin B genetic 1 1 1 Negative Genetic
GSP1 YLR293C Ran GTPase genetic 1 1 1 Positive Genetic
CDC53 YDL132W Cullin genetic 1 1 1 Positive Genetic
ILV5 YLR355C Acetohydroxyacid reductoisomerase and mtDNA binding protein genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein physical 1 1 1 Affinity Capture-MS
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Negative Genetic
BUD13 YGL174W Subunit of the RES complex genetic 1 1 1 Negative Genetic
SEC53 YFL045C Phosphomannomutase genetic 1 1 1 Negative Genetic
LCP5 YER127W Essential protein involved in maturation of 18S rRNA genetic 1 1 1 Negative Genetic
ESL2 YKR096W hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Negative Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Positive Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Negative Genetic
AGX1 YFL030W Alanine:glyoxylate aminotransferase (AGT) genetic 1 1 1 Negative Genetic
ATG12 YBR217W Ubiquitin-like modifier involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
HEF3 YNL014W Translational elongation factor EF-3 genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Positive Genetic
APT1 YML022W Adenine phosphoribosyltransferase genetic 1 1 1 Negative Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Negative Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
DOP1 YDR141C Protein involved in vesicular transport at trans-Golgi network (TGN) genetic 1 1 1 Negative Genetic
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 1 1 1 Negative Genetic
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
IMD4 YML056C Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
GID8 YMR135C Subunit of GID Complex, binds strongly to central component Vid30p genetic 1 1 1 Negative Genetic
BUD32 YGR262C Protein kinase genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 1 1 1 Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Positive Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 1 1 1 Affinity Capture-MS
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 1 1 1 Negative Genetic
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Biochemical Activity
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Negative Genetic
MCX1 YBR227C Non-proteolytic ATPase of the AAA family genetic 1 1 1 Positive Genetic
ARE1 YCR048W Acyl-CoA:sterol acyltransferase genetic 1 1 1 Positive Genetic
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis physical 1 1 1 Affinity Capture-MS
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Negative Genetic
MAG1 YER142C 3-methyl-adenine DNA glycosylase genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 genetic 1 1 1 Synthetic Rescue
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation physical 1 1 1 Affinity Capture-MS
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
RAD59 YDL059C Protein involved DNA double-strand break repair genetic 1 1 1 Negative Genetic
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 1 1 1 Negative Genetic
ATG20 YDL113C Sorting nexin family member genetic 1 1 1 Positive Genetic
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase genetic 1 1 1 Positive Genetic
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Negative Genetic
MIH1 YMR036C Protein tyrosine phosphatase physical 1 1 1 Biochemical Activity
MAP2 YBL091C Methionine aminopeptidase genetic 1 1 1 Negative Genetic
NOP53 YPL146C Nucleolar protein physical 1 1 1 Affinity Capture-MS
MDH2 YOL126C Cytoplasmic malate dehydrogenase genetic 1 1 1 Negative Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Positive Genetic
APA1 YCL050C AP4A phosphorylase genetic 1 1 1 Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 1 1 1 Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Negative Genetic
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
GBP2 YCL011C Poly(A+) RNA-binding protein genetic 1 1 1 Negative Genetic
ISA1 YLL027W Protein required for maturation of mitochondrial [4Fe-4S] proteins genetic 1 1 1 Negative Genetic
GPA1 YHR005C Subunit of G protein involved in pheromone response genetic 1 1 1 Synthetic Rescue
CSC1 YLR241W Calcium permeable gated cation channel genetic 1 1 1 Negative Genetic
ADH6 YMR318C NADPH-dependent medium chain alcohol dehydrogenase genetic 1 1 1 Negative Genetic
MDH3 YDL078C Peroxisomal malate dehydrogenase genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
MGT1 YDL200C DNA repair methyltransferase (6-O-methylguanine-DNA methylase) genetic 1 1 1 Negative Genetic
RAD28 YDR030C Protein involved in DNA repair genetic 1 1 1 Negative Genetic
PKH1 YDR490C Serine/threonine protein kinase genetic 1 1 1 Positive Genetic
EXG1 YLR300W Major exo-1,3-beta-glucanase of the cell wall genetic 1 1 1 Positive Genetic
PSO2 YMR137C Nuclease required for DNA single- and double-strand break repair genetic 1 1 1 Positive Genetic
REX2 YLR059C 3'-5' RNA exonuclease genetic 1 1 1 Positive Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
ATP7 YKL016C Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
FZF1 YGL254W Transcription factor involved in sulfite metabolism genetic 1 1 1 Negative Genetic
PEX29 YDR479C ER-resident protein involved in peroxisomal biogenesis genetic 1 1 1 Negative Genetic
NAS2 YIL007C Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 1 1 1 Negative Genetic
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
ATG16 YMR159C Conserved protein involved in autophagy genetic 1 1 1 Negative Genetic
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Rescue
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Negative Genetic
EBS1 YDR206W Protein involved in translation inhibition and nonsense-mediated decay genetic 1 1 1 Negative Genetic
ECM19 YLR390W Protein of unknown function genetic 1 1 1 Negative Genetic
ENT3 YJR125C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Negative Genetic
KAR4 YCL055W Transcription factor required for response to pheromones genetic 1 1 1 Negative Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
NDL1 YLR254C Homolog of nuclear distribution factor NudE genetic 1 1 1 Negative Genetic
CLG1 YGL215W Cyclin-like protein that interacts with Pho85p genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Positive Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
RPS26B YER131W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SAP4 YGL229C Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
NTC20 YBR188C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
DAS2 YDR020C Putative protein of unknown function genetic 1 1 1 Negative Genetic
CNL1 YDR357C Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Positive Genetic
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance genetic 1 1 1 Positive Genetic
PIR5 YJL160C Putative protein of unknown function genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
ITT1 YML068W Protein that modulates the efficiency of translation termination genetic 1 1 1 Negative Genetic
HUA1 YGR268C Cytoplasmic protein containing a zinc finger domain genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Positive Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Positive Genetic
HTL1 YCR020W-B Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
NHP6A YPR052C High-mobility group (HMG) protein physical 1 1 1 Affinity Capture-MS
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Positive Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-MS
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 1 1 1 Synthetic Lethality
COX18 YGR062C Protein required for membrane insertion of C-terminus of Cox2p genetic 1 1 1 Negative Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 1 1 1 Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Positive Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
MYO5 YMR109W One of two type I myosin motors genetic 1 1 1 Positive Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA genetic 1 1 1 Negative Genetic
PRK1 YIL095W Ser/Thr protein kinase physical 1 1 1 Affinity Capture-MS
PRK1 YIL095W Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Negative Genetic
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 1 1 1 Positive Genetic
ERV41 YML067C Protein localized to COPII-coated vesicles genetic 1 1 1 Positive Genetic
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation genetic 1 1 1 Negative Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
HAP1 YLR256W Zinc finger transcription factor genetic 1 1 1 Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Positive Genetic
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
RRN7 YJL025W Component of the core factor (CF) rDNA transcription factor complex genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
SGM1 YJR134C Protein of unknown function genetic 1 1 1 Negative Genetic
EMC1 YCL045C Member of conserved endoplasmic reticulum membrane complex genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 1 1 1 Negative Genetic
BNR1 YIL159W Formin genetic 1 1 1 Negative Genetic
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 1 1 1 Positive Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Synthetic Growth Defect
RRN9 YMR270C Protein involved in promoting high level transcription of rDNA genetic 1 1 1 Negative Genetic
CAF16 YFL028C Part of evolutionarily-conserved CCR4-NOT regulatory complex genetic 1 1 1 Negative Genetic
ERG25 YGR060W C-4 methyl sterol oxidase genetic 1 1 1 Negative Genetic
ESC1 YMR219W Protein involved in telomeric silencing genetic 1 1 1 Negative Genetic
GAD1 YMR250W Glutamate decarboxylase genetic 1 1 1 Negative Genetic
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Positive Genetic
MEI4 YER044C-A Meiosis-specific protein involved in forming DSBs genetic 1 1 1 Negative Genetic
REC107 YJR021C Protein involved in early stages of meiotic recombination genetic 1 1 1 Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
ECM27 YJR106W Protein involved in calcium homeostasis and exit from quiescence genetic 1 1 1 Negative Genetic
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 1 1 1 Negative Genetic
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
NNK1 YKL171W Protein kinase genetic 1 1 1 Positive Genetic
ARK1 YNL020C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase physical 1 1 1 Biochemical Activity
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Negative Genetic
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly genetic 1 1 1 Negative Genetic
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I genetic 1 1 1 Negative Genetic
HHT2 YNL031C Histone H3 genetic 1 1 1 Synthetic Rescue
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Negative Genetic
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway genetic 1 1 1 Negative Genetic
ATG10 YLL042C Conserved E2-like conjugating enzyme genetic 1 1 1 Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Positive Genetic
RPL11A YPR102C Ribosomal 60S subunit protein L11A genetic 1 1 1 Negative Genetic
ENT1 YDL161W Epsin-like protein involved in endocytosis and actin patch assembly genetic 1 1 1 Positive Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Negative Genetic
INP51 YIL002C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Negative Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Positive Genetic
PER33 YLR064W Protein that localizes to the endoplasmic reticulum genetic 1 1 1 Positive Genetic
MCR1 YKL150W Mitochondrial NADH-cytochrome b5 reductase genetic 1 1 1 Positive Genetic
ABZ1 YNR033W Para-aminobenzoate (PABA) synthase genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Positive Genetic
RRS1 YOR294W Essential protein that binds ribosomal protein L11 physical 1 1 1 Affinity Capture-MS
RRS1 YOR294W Essential protein that binds ribosomal protein L11 genetic 1 1 1 Negative Genetic
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MIT1 YEL007W Transcriptional regulator of pseudohyphal growth genetic 1 1 1 Negative Genetic
QDR3 YBR043C Multidrug transporter of the major facilitator superfamily genetic 1 1 1 Positive Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
REV7 YIL139C Accessory subunit of DNA polymerase zeta genetic 1 1 1 Negative Genetic
CCC1 YLR220W Vacuolar Fe2+/Mn2+ transporter genetic 1 1 1 Negative Genetic
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis genetic 1 1 1 Negative Genetic
EMC6 YLL014W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 1 1 1 Positive Genetic
SDH1 YKL148C Flavoprotein subunit of succinate dehydrogenase genetic 1 1 1 Negative Genetic
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
POG1 YIL122W DNA-binding transcriptional activator genetic 1 1 1 Negative Genetic
CIT1 YNR001C Mitochondrial citrate synthase genetic 1 1 1 Negative Genetic
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Negative Genetic
ATF1 YOR377W Alcohol acetyltransferase genetic 1 1 1 Negative Genetic
GEF1 YJR040W Voltage-gated chloride channel genetic 1 1 1 Positive Genetic
PDR11 YIL013C ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
PAM17 YKR065C Constituent of the TIM23 complex genetic 1 1 1 Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 1 1 1 Positive Genetic
MIG3 YER028C Transcriptional regulator genetic 1 1 1 Negative Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
CUE1 YMR264W Ubiquitin-binding protein genetic 1 1 1 Positive Genetic
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) genetic 1 1 1 Negative Genetic
BTT1 YDR252W Heterotrimeric nascent polypeptide-associated complex beta3 subunit genetic 1 1 1 Negative Genetic
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Negative Genetic
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase genetic 1 1 1 Negative Genetic
PHO11 YAR071W One of three repressible acid phosphatases genetic 1 1 1 Negative Genetic
IRC7 YFR055W Cysteine desulphydrase, enables growth on cysteine as nitrogen source genetic 1 1 1 Negative Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
PHR1 YOR386W DNA photolyase involved in photoreactivation genetic 1 1 1 Negative Genetic
NSI1 YDR026C RNA polymerase I termination factor genetic 1 1 1 Negative Genetic
AVT1 YJR001W Vacuolar transporter genetic 1 1 1 Negative Genetic
EKI1 YDR147W Ethanolamine kinase genetic 1 1 1 Negative Genetic
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
GUK1 YDR454C Guanylate kinase genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
GEP7 YGL057C Protein of unknown function genetic 1 1 1 Positive Genetic
NPY1 YGL067W NADH diphosphatase (pyrophosphatase) genetic 1 1 1 Positive Genetic
PSD2 YGR170W Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes genetic 1 1 1 Negative Genetic
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Negative Genetic
MVB12 YGR206W ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers genetic 1 1 1 Negative Genetic
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis physical 1 1 1 Affinity Capture-MS
NOP19 YGR251W Ribosome biogenesis factor genetic 1 1 1 Positive Genetic
GUT1 YHL032C Glycerol kinase genetic 1 1 1 Positive Genetic
PDR10 YOR328W ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
ATP12 YJL180C Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
RTC4 YNL254C Protein of unknown function genetic 1 1 1 Negative Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Negative Genetic
RTC3 YHR087W Protein of unknown function involved in RNA metabolism genetic 1 1 1 Negative Genetic
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 1 1 1 Negative Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
MUK1 YPL070W Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 1 1 1 Negative Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Positive Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
KAE1 YKR038C Highly conserved ATPase of HSP70/DnaK family genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Negative Genetic
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p genetic 1 1 1 Negative Genetic
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
GCV3 YAL044C H subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
ANY1 YMR010W Protein involved in phospholipid flippase function genetic 1 1 1 Positive Genetic
HFD1 YMR110C Dehydrogenase involved in ubiquinone and sphingolipid metabolism genetic 1 1 1 Negative Genetic
PAD1 YDR538W Phenylacrylic acid decarboxylase genetic 1 1 1 Negative Genetic
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
RRG7 YOR305W Protein of unknown function genetic 1 1 1 Negative Genetic
MCY1 YGR012W Putative cysteine synthase physical 1 1 1 Affinity Capture-MS
MCY1 YGR012W Putative cysteine synthase genetic 1 1 1 Negative Genetic
AIM23 YJL131C Mitochondrial translation initiation factor 3 (IF3, mIF3) physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PST1 YDR055W Cell wall protein that contains a putative GPI-attachment site genetic 1 1 1 Positive Genetic
EGH1 YIR007W Steryl-beta-glucosidase with broad specificity for aglycones genetic 1 1 1 Positive Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Positive Genetic
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL24A YGL031C Ribosomal 60S subunit protein L24A genetic 1 1 1 Negative Genetic
GAA1 YLR088W Subunit of the GPI:protein transamidase complex genetic 1 1 1 Positive Genetic
RPL4B YDR012W Ribosomal 60S subunit protein L4B genetic 1 1 1 Positive Genetic
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b genetic 1 1 1 Negative Genetic
RTR1 YER139C Dual specificity protein phosphatase genetic 1 1 1 Negative Genetic
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Positive Genetic
NHA1 YLR138W Na+/H+ antiporter genetic 1 1 1 Negative Genetic
CLB4 YLR210W B-type cyclin involved in cell cycle progression genetic 1 1 1 Positive Genetic
IPT1 YDR072C Inositolphosphotransferase genetic 1 1 1 Positive Genetic
HEM1 YDR232W 5-aminolevulinate synthase genetic 1 1 1 Negative Genetic
RPL35B YDL136W Ribosomal 60S subunit protein L35B genetic 1 1 1 Negative Genetic
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CDA1 YLR307W Chitin deacetylase genetic 1 1 1 Negative Genetic
CTH1 YDR151C mRNA binding protein, member of the CCCH zinc finger family genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Positive Genetic
ORM1 YGR038W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Positive Genetic
DIF1 YLR437C Protein that regulates nuclear import of Rnr2p and Rnr4p genetic 1 1 1 Negative Genetic
PSP1 YDR505C Asn and gln rich protein of unknown function genetic 1 1 1 Negative Genetic
RDR1 YOR380W Transcriptional repressor involved in regulating multidrug resistance genetic 1 1 1 Negative Genetic
GAS3 YMR215W Putative 1,3-beta-glucanosyltransferase genetic 1 1 1 Negative Genetic
APS2 YJR058C Small subunit of the clathrin-associated adaptor complex AP-2 genetic 1 1 1 Positive Genetic
PMT6 YGR199W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Negative Genetic
NMD4 YLR363C Protein that may be involved in nonsense-mediated mRNA decay genetic 1 1 1 Negative Genetic
DIA1 YMR316W Protein of unknown function genetic 1 1 1 Positive Genetic
PNT1 YOR266W Mitochondrial integral inner membrane protein genetic 1 1 1 Negative Genetic
AAD4 YDL243C Putative aryl-alcohol dehydrogenase genetic 1 1 1 Negative Genetic
DOT5 YIL010W Nuclear thiol peroxidase genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Positive Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Negative Genetic
POT1 YIL160C 3-ketoacyl-CoA thiolase with broad chain length specificity genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
RQT4 YKR023W Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Positive Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
MNN5 YJL186W Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
GIS1 YDR096W Histone demethylase and transcription factor genetic 1 1 1 Negative Genetic
OM14 YBR230C Mitochondrial outer membrane receptor for cytosolic ribosomes genetic 1 1 1 Negative Genetic
MRX18 YBR056W Putative glycoside hydrolase of the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
ECL1 YGR146C Protein of unknown function genetic 1 1 1 Negative Genetic
CRH1 YGR189C Chitin transglycosylase genetic 1 1 1 Negative Genetic
APE4 YHR113W Cytoplasmic aspartyl aminopeptidase with possible vacuole function genetic 1 1 1 Negative Genetic
JJJ3 YJR097W Iron-binding protein genetic 1 1 1 Negative Genetic
ASI2 YNL159C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
PNP1 YLR209C Purine nucleoside phosphorylase genetic 1 1 1 Positive Genetic
RBA50 YDR527W Protein involved in transcription genetic 1 1 1 Negative Genetic
EAR1 YMR171C Specificity factor required for Rsp5p-dependent ubiquitination genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
RIP1 YEL024W Ubiquinol-cytochrome-c reductase genetic 1 1 1 Negative Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Negative Genetic
FCY2 YER056C Purine-cytosine permease genetic 1 1 1 Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
CTR2 YHR175W Low-affinity copper transporter of the vacuolar membrane genetic 1 1 1 Negative Genetic
RBS1 YDL189W Protein involved in assembly of the RNA Pol III complex genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
MSC3 YLR219W Protein of unknown function genetic 1 1 1 Positive Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Negative Genetic
DCW1 YKL046C Putative mannosidase genetic 1 1 1 Positive Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Negative Genetic
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 1 1 1 Negative Genetic
RIB7 YBR153W Diaminohydroxyphoshoribosylaminopyrimidine deaminase genetic 1 1 1 Negative Genetic
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type genetic 1 1 1 Positive Genetic
ATG15 YCR068W Phospholipase genetic 1 1 1 Negative Genetic
FAD1 YDL045C Flavin adenine dinucleotide (FAD) synthetase genetic 1 1 1 Negative Genetic
RDS1 YCR106W Putative zinc cluster transcription factor genetic 1 1 1 Negative Genetic
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Negative Genetic
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase genetic 1 1 1 Negative Genetic
MRX12 YJR003C Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
PDL32 YMR087W Putative ADP-ribose-1''-monophosphatase genetic 1 1 1 Positive Genetic
FEX2 YPL279C Protein involved in fluoride export genetic 1 1 1 Negative Genetic
COX12 YLR038C Subunit VIb of cytochrome c oxidase genetic 1 1 1 Negative Genetic
RFU1 YLR073C Protein that inhibits Doa4p deubiquitinating activity genetic 1 1 1 Negative Genetic
PIR3 YKL163W O-glycosylated covalently-bound cell wall protein genetic 1 1 1 Positive Genetic
PUN1 YLR414C Plasma membrane protein with a role in cell wall integrity genetic 1 1 1 Negative Genetic
SED4 YCR067C Integral ER membrane protein that stimulates Sar1p GTPase activity genetic 1 1 1 Negative Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
COX20 YDR231C Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
PIR1 YKL164C O-glycosylated protein required for cell wall stability genetic 1 1 1 Negative Genetic
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 1 1 1 Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 1 1 1 Negative Genetic
MTC3 YGL226W Protein of unknown function genetic 1 1 1 Positive Genetic
LIH1 YJR107W Putative lipase genetic 1 1 1 Negative Genetic
MXR2 YCL033C Methionine-R-sulfoxide reductase genetic 1 1 1 Negative Genetic
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
CMC1 YKL137W Copper-binding protein of the mitochondrial intermembrane space genetic 1 1 1 Positive Genetic
AAD10 YJR155W Putative aryl-alcohol dehydrogenase genetic 1 1 1 Negative Genetic
MNT2 YGL257C Mannosyltransferase genetic 1 1 1 Positive Genetic
HPF1 YOL155C Haze-protective mannoprotein genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Negative Genetic
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
MCH4 YOL119C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Negative Genetic
HBN1 YCL026C-B Protein of unknown function genetic 1 1 1 Negative Genetic
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 1 1 1 Negative Genetic
COS5 YJR161C Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
HIM1 YDR317W Protein of unknown function involved in DNA repair genetic 1 1 1 Negative Genetic
DLT1 YMR126C Protein of unknown function genetic 1 1 1 Positive Genetic
GAS2 YLR343W 1,3-beta-glucanosyltransferase genetic 1 1 1 Positive Genetic
PIC2 YER053C Mitochondrial copper and phosphate carrier genetic 1 1 1 Positive Genetic
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p genetic 1 1 1 Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Positive Genetic
SEO1 YAL067C Putative permease genetic 1 1 1 Negative Genetic
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
ITR2 YOL103W Myo-inositol transporter genetic 1 1 1 Positive Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
PTK1 YKL198C Putative serine/threonine protein kinase genetic 1 1 1 Negative Genetic
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
EMC2 YJR088C Member of conserved ER transmembrane complex genetic 1 1 1 Positive Genetic
MAL32 YBR299W Maltase (alpha-D-glucosidase) genetic 1 1 1 Negative Genetic
EFM2 YBR271W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
MRX19 YDL183C Protein that may form an active mitochondrial KHE system genetic 1 1 1 Negative Genetic
OSW2 YLR054C Protein of unknown function reputedly involved in spore wall assembly genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Negative Genetic
SFA1 YDL168W Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase genetic 1 1 1 Negative Genetic
REE1 YJL217W Cytoplasmic protein involved in the regulation of enolase (ENO1) genetic 1 1 1 Negative Genetic
OPI10 YOL032W Protein with a possible role in phospholipid biosynthesis genetic 1 1 1 Negative Genetic
EAT1 YGR015C Ethanol acetyltransferase genetic 1 1 1 Negative Genetic
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Positive Genetic
PAN6 YIL145C Pantothenate synthase genetic 1 1 1 Positive Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
RQC1 YDR333C Component of the ribosome quality control complex (RQC) genetic 1 1 1 Negative Genetic
MRX8 YDR336W Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Positive Genetic
NCE101 YJL205C Protein of unknown function genetic 1 1 1 Positive Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Positive Genetic
HPM1 YIL110W AdoMet-dependent methyltransferase genetic 1 1 1 Positive Genetic
AAT1 YKL106W Mitochondrial aspartate aminotransferase genetic 1 1 1 Positive Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
DPA10 YLR307C-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
REG2 YBR050C Regulatory subunit of the Glc7p type-1 protein phosphatase genetic 1 1 1 Negative Genetic
FMT1 YBL013W Methionyl-tRNA formyltransferase genetic 1 1 1 Negative Genetic
NCA3 YJL116C Protein involved in mitochondrion organization genetic 1 1 1 Negative Genetic
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 1 1 1 Negative Genetic
PUS2 YGL063W Mitochondrial tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Positive Genetic
SEC59 YMR013C Dolichol kinase genetic 1 1 1 Negative Genetic
RNP1 YLL046C Ribonucleoprotein that contains two RNA recognition motifs (RRM) genetic 1 1 1 Positive Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Positive Genetic
MNL2 YLR057W Putative mannosidase involved in ER-associated protein degradation genetic 1 1 1 Negative Genetic
PEX9 YMR018W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Positive Genetic
NIT1 YIL164C Nitrilase genetic 1 1 1 Positive Genetic
RRT12 YCR045C Probable subtilisin-family protease genetic 1 1 1 Negative Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 1 1 1 Negative Genetic
MAN2 YNR073C Mannitol dehydrogenase genetic 1 1 1 Negative Genetic
MMO1 YKL044W Protein of unknown function genetic 1 1 1 Positive Genetic
MIN3 YMR182W-A Mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
DGR1 YNL130C-A Protein of unknown function genetic 1 1 1 Negative Genetic