Standard name Systematic name Name description Description
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails Single stranded DNA-binding protein found at TG1-3 telomere G-tails; key roles in regulation of telomerase, telomere end protection, conventional telomere replication; regulates telomere replication through recruitment of specific sub-complexes, essential function is telomere capping; forms homodimer via N-terminus; disruption of dimerization leads to short telomeres; autophagy and proteasome are involved in Cdc13p degradation; differentially phosphorylated through cell cycle
Visualize the interactome of CDC13
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 26

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.130 NaN 0.119
Mito 0.478 0.682 0.536
Nucleus 0.543 0.545 0.452
Vac/Vac Memb 0.185 0.182 0.155

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 319

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CDC13 10 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 26 6 22 Synthetic Rescue, Synthetic Rescue, Synthetic Lethality, Phenotypic Suppression, Synthetic Growth Defect, Synthetic Lethality, Phenotypic Suppression, Phenotypic Enhancement, Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Phenotypic Enhancement, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect, Positive Genetic, Synthetic Rescue, Synthetic Rescue
STN1 YDR082W Telomere end-binding and capping protein physical 22 3 18 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease genetic 21 6 16 Phenotypic Suppression, Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Lethality, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Positive Genetic, Synthetic Rescue, Phenotypic Enhancement, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue
RAD24 YER173W Checkpoint protein genetic 15 5 12 Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement, Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Positive Genetic, Synthetic Rescue, Synthetic Rescue
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder genetic 11 5 9 Dosage Lethality, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Dosage Growth Defect, Synthetic Rescue, Synthetic Lethality, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue
STN1 YDR082W Telomere end-binding and capping protein genetic 11 5 8 Dosage Rescue, Synthetic Lethality, Phenotypic Enhancement, Phenotypic Suppression, Dosage Rescue, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Phenotypic Enhancement
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 10 3 7 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 9 5 9 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Phenotypic Enhancement
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails physical 9 4 5 Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Co-crystal Structure, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 8 4 8 Phenotypic Enhancement, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Phenotypic Suppression, Phenotypic Suppression
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 7 4 6 Synthetic Rescue, Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Enhancement, Positive Genetic, Synthetic Rescue
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex physical 7 4 5 Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Co-crystal Structure, Reconstituted Complex, Two-hybrid
TEN1 YLR010C Protein that regulates telomeric length physical 7 3 4 Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 6 4 6 Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 6 5 5 Dosage Growth Defect, Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Enhancement, Positive Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 6 4 5 Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Rescue
BMH1 YER177W 14-3-3 protein, major isoform genetic 6 3 5 Synthetic Rescue, Synthetic Rescue, Dosage Rescue, Synthetic Rescue, Positive Genetic, Positive Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 6 3 5 Synthetic Growth Defect, Dosage Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 6 2 5 Synthetic Rescue, Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 6 2 5 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Positive Genetic, Synthetic Rescue, Synthetic Rescue
RAD52 YML032C Protein involved in homologous recombination genetic 5 4 5 Phenotypic Suppression, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement
RIF1 YBR275C Protein involved in control of DNA replication genetic 5 4 5 Phenotypic Enhancement, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SAN1 YDR143C Ubiquitin-protein ligase genetic 5 3 5 Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue, Positive Genetic, Positive Genetic
RIF2 YLR453C Protein that binds to the Rap1p C-terminus genetic 5 3 5 Synthetic Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Rescue, Positive Genetic
RAD17 YOR368W Checkpoint protein genetic 5 3 4 Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue, Positive Genetic, Positive Genetic
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein genetic 5 2 4 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 4 4 4 Dosage Rescue, Synthetic Growth Defect, Phenotypic Suppression, Negative Genetic
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions genetic 4 4 4 Synthetic Rescue, Dosage Lethality, Positive Genetic, Phenotypic Enhancement
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 4 2 4 Dosage Rescue, Synthetic Rescue, Dosage Rescue, Dosage Rescue
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 4 2 4 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 4 1 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
DDC1 YPL194W DNA damage checkpoint protein genetic 4 4 3 Phenotypic Suppression, Synthetic Rescue, Synthetic Growth Defect, Positive Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 4 4 3 Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression, Positive Genetic
EBS1 YDR206W Protein involved in translation inhibition and nonsense-mediated decay genetic 4 2 3 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Positive Genetic
TEN1 YLR010C Protein that regulates telomeric length genetic 3 3 3 Dosage Rescue, Synthetic Lethality, Phenotypic Enhancement
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway genetic 3 3 3 Synthetic Rescue, Positive Genetic, Negative Genetic
KIN3 YAR018C Nonessential serine/threonine protein kinase genetic 3 3 3 Synthetic Rescue, Positive Genetic, Dosage Growth Defect
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 3 3 3 Synthetic Rescue, Positive Genetic, Negative Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 3 3 3 Synthetic Rescue, Positive Genetic, Negative Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 3 3 3 Synthetic Growth Defect, Negative Genetic, Synthetic Lethality
BUB2 YMR055C Mitotic exit network regulator genetic 3 3 3 Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 3 3 3 Synthetic Growth Defect, Synthetic Rescue, Phenotypic Enhancement
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 3 2 3 Co-localization, Biochemical Activity, Biochemical Activity
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Positive Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 3 2 3 Synthetic Rescue, Positive Genetic, Positive Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 3 2 3 Synthetic Rescue, Positive Genetic, Positive Genetic
OCA2 YNL056W Protein of unknown function genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Negative Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 3 2 3 Synthetic Rescue, Positive Genetic, Positive Genetic
TMA22 YJR014W Protein of unknown function genetic 3 2 3 Synthetic Rescue, Positive Genetic, Positive Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 3 2 3 Synthetic Lethality, Positive Genetic, Positive Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
BUD32 YGR262C Protein kinase genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Dosage Growth Defect
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 3 2 3 Synthetic Rescue, Positive Genetic, Positive Genetic
CGI121 YML036W Component of the EKC/KEOPS complex genetic 3 1 3 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 3 3 2 Synthetic Growth Defect, Synthetic Lethality, Phenotypic Suppression
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 3 3 2 Synthetic Rescue, Synthetic Growth Defect, Positive Genetic
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family genetic 3 3 2 Synthetic Rescue, Synthetic Growth Defect, Positive Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 3 3 2 Synthetic Rescue, Synthetic Growth Defect, Positive Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 3 3 2 Synthetic Rescue, Synthetic Growth Defect, Positive Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 3 3 2 Synthetic Rescue, Synthetic Growth Defect, Positive Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 3 3 2 Synthetic Rescue, Synthetic Growth Defect, Positive Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 3 3 2 Synthetic Rescue, Synthetic Growth Defect, Positive Genetic
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 3 3 2 Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 3 3 2 Synthetic Rescue, Synthetic Growth Defect, Positive Genetic
UTH1 YKR042W Mitochondrial inner membrane protein genetic 3 3 2 Synthetic Rescue, Synthetic Growth Defect, Positive Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 3 2 2 Dosage Rescue, Negative Genetic, Negative Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 3 2 2 Synthetic Rescue, Synthetic Rescue, Positive Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
IMP4 YNL075W Component of the SSU processome physical 3 3 1 Two-hybrid, Reconstituted Complex, Affinity Capture-Western
ZDS2 YML109W Protein with a role in regulating Swe1p-dependent polarized growth physical 3 3 1 Two-hybrid, Reconstituted Complex, Affinity Capture-Western
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 2 2 2 Synthetic Rescue, Positive Genetic
BUD14 YAR014C Protein involved in bud-site selection genetic 2 2 2 Synthetic Rescue, Positive Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 2 2 2 Negative Genetic, Dosage Growth Defect
PDS1 YDR113C Securin genetic 2 2 2 Phenotypic Enhancement, Synthetic Rescue
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RTC1 YOL138C Subunit of SEACAT, a subcomplex of the SEA complex genetic 2 2 2 Synthetic Rescue, Positive Genetic
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family genetic 2 2 2 Synthetic Rescue, Positive Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 2 2 2 Synthetic Rescue, Positive Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 2 2 2 Synthetic Rescue, Positive Genetic
FET3 YMR058W Ferro-O2-oxidoreductase genetic 2 2 2 Synthetic Rescue, Positive Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 2 2 2 Synthetic Rescue, Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 2 2 Synthetic Rescue, Positive Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 2 2 2 Synthetic Rescue, Positive Genetic
RPL16B YNL069C Ribosomal 60S subunit protein L16B genetic 2 2 2 Synthetic Rescue, Positive Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 2 2 2 Synthetic Rescue, Positive Genetic
ELO3 YLR372W Elongase genetic 2 2 2 Synthetic Rescue, Positive Genetic
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 2 2 2 Synthetic Rescue, Positive Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 2 2 2 Synthetic Rescue, Positive Genetic
HEM25 YDL119C Mitochondrial glycine transporter genetic 2 2 2 Synthetic Rescue, Positive Genetic
YIL055C YIL055C Putative protein of unknown function genetic 2 2 2 Synthetic Rescue, Positive Genetic
RGI2 YIL057C Protein of unknown function genetic 2 2 2 Synthetic Rescue, Positive Genetic
YIL161W YIL161W Putative protein of unknown function genetic 2 2 2 Synthetic Rescue, Positive Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 2 2 2 Synthetic Rescue, Positive Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 2 2 2 Synthetic Rescue, Positive Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 2 2 2 Synthetic Rescue, Positive Genetic
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) genetic 2 2 2 Synthetic Rescue, Positive Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 2 2 2 Synthetic Rescue, Positive Genetic
CYT1 YOR065W Cytochrome c1 genetic 2 2 2 Synthetic Rescue, Negative Genetic
DIE2 YGR227W Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase genetic 2 2 2 Synthetic Rescue, Positive Genetic
FTR1 YER145C High affinity iron permease genetic 2 2 2 Synthetic Rescue, Positive Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 2 2 2 Synthetic Rescue, Positive Genetic
FYV10 YIL097W Subunit of GID complex genetic 2 2 2 Synthetic Rescue, Positive Genetic
GEF1 YJR040W Voltage-gated chloride channel genetic 2 2 2 Synthetic Rescue, Positive Genetic
GET1 YGL020C Subunit of the GET complex genetic 2 2 2 Synthetic Rescue, Negative Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 2 2 2 Synthetic Rescue, Positive Genetic
HCM1 YCR065W Forkhead transcription factor genetic 2 2 2 Synthetic Rescue, Positive Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 2 2 2 Synthetic Rescue, Positive Genetic
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 2 2 2 Synthetic Rescue, Positive Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 2 2 2 Synthetic Rescue, Positive Genetic
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 2 2 2 Synthetic Rescue, Positive Genetic
HPM1 YIL110W AdoMet-dependent methyltransferase genetic 2 2 2 Synthetic Rescue, Positive Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 2 2 2 Synthetic Rescue, Positive Genetic
NOP16 YER002W Constituent of 66S pre-ribosomal particles genetic 2 2 2 Synthetic Rescue, Positive Genetic
OGG1 YML060W Nuclear and mitochondrial glycosylase/lyase genetic 2 2 2 Synthetic Rescue, Positive Genetic
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 2 2 2 Synthetic Rescue, Positive Genetic
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein genetic 2 2 2 Synthetic Rescue, Positive Genetic
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 2 2 2 Synthetic Rescue, Positive Genetic
POT1 YIL160C 3-ketoacyl-CoA thiolase with broad chain length specificity genetic 2 2 2 Synthetic Rescue, Positive Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 2 2 2 Synthetic Rescue, Positive Genetic
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase genetic 2 2 2 Synthetic Rescue, Positive Genetic
RPL13A YDL082W Ribosomal 60S subunit protein L13A genetic 2 2 2 Synthetic Rescue, Positive Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 2 2 2 Synthetic Rescue, Positive Genetic
RPL35A YDL191W Ribosomal 60S subunit protein L35A genetic 2 2 2 Synthetic Rescue, Positive Genetic
RPL37A YLR185W Ribosomal 60S subunit protein L37A genetic 2 2 2 Synthetic Rescue, Positive Genetic
RPL37B YDR500C Ribosomal 60S subunit protein L37B genetic 2 2 2 Synthetic Rescue, Positive Genetic
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 2 2 2 Synthetic Rescue, Positive Genetic
RPL6B YLR448W Ribosomal 60S subunit protein L6B genetic 2 2 2 Synthetic Rescue, Positive Genetic
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 2 2 2 Synthetic Rescue, Positive Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 2 2 2 Synthetic Rescue, Positive Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 2 2 2 Synthetic Rescue, Positive Genetic
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 2 2 2 Synthetic Rescue, Positive Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 2 2 2 Synthetic Rescue, Positive Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 2 2 2 Synthetic Rescue, Positive Genetic
TAL1 YLR354C Transaldolase, enzyme in the non-oxidative pentose phosphate pathway genetic 2 2 2 Synthetic Rescue, Positive Genetic
TKL1 YPR074C Transketolase genetic 2 2 2 Synthetic Rescue, Positive Genetic
TMA20 YER007C-A Protein of unknown function that associates with ribosomes genetic 2 2 2 Synthetic Rescue, Positive Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 2 2 2 Synthetic Rescue, Positive Genetic
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 2 2 2 Synthetic Rescue, Positive Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 2 2 2 Synthetic Rescue, Positive Genetic
VHS2 YIL135C Regulator of septin dynamics genetic 2 2 2 Synthetic Rescue, Negative Genetic
VID28 YIL017C GID Complex subunit, serves as adaptor for regulatory subunit Vid24p genetic 2 2 2 Synthetic Rescue, Positive Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 2 2 Synthetic Rescue, Positive Genetic
YMC2 YBR104W Putative mitochondrial inner membrane transporter genetic 2 2 2 Synthetic Rescue, Positive Genetic
YPT6 YLR262C Rab family GTPase genetic 2 2 2 Synthetic Rescue, Positive Genetic
YPT7 YML001W Rab family GTPase genetic 2 2 2 Synthetic Rescue, Positive Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
PHO5 YBR093C Repressible acid phosphatase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
STB5 YHR178W Transcription factor genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
CDC73 YLR418C Component of the Paf1p complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
ERV14 YGL054C COPII-coated vesicle protein genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
EST3 YIL009C-A Component of the telomerase holoenzyme genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 2 2 2 Synthetic Rescue, Positive Genetic
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 2 2 2 Synthetic Rescue, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit genetic 2 2 2 Synthetic Growth Defect, Phenotypic Enhancement
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
DPB4 YDR121W Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 2 2 2 Negative Genetic, Dosage Growth Defect
GUF1 YLR289W Mitochondrial matrix GTPase genetic 2 2 2 Positive Genetic, Negative Genetic
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B genetic 2 2 2 Positive Genetic, Negative Genetic
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 2 2 2 Positive Genetic, Negative Genetic
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase genetic 2 2 2 Synthetic Rescue, Positive Genetic
AIR1 YIL079C Zinc knuckle protein genetic 2 2 2 Synthetic Rescue, Positive Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 2 2 2 Synthetic Rescue, Positive Genetic
BAS1 YKR099W Myb-related transcription factor genetic 2 2 2 Synthetic Rescue, Positive Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
BNR1 YIL159W Formin genetic 2 2 2 Synthetic Rescue, Positive Genetic
CAP2 YIL034C Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 2 2 2 Synthetic Rescue, Positive Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 2 2 2 Synthetic Lethality, Phenotypic Suppression
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 2 2 2 Synthetic Rescue, Positive Genetic
AVT5 YBL089W Putative transporter genetic 2 2 2 Synthetic Rescue, Positive Genetic
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 2 2 2 Synthetic Rescue, Positive Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member physical 2 1 2 Biochemical Activity, Biochemical Activity
SAN1 YDR143C Ubiquitin-protein ligase physical 2 1 2 Two-hybrid, Two-hybrid
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity genetic 2 1 2 Negative Genetic, Negative Genetic
DPH5 YLR172C Methyltransferase required for synthesis of diphthamide genetic 2 1 2 Negative Genetic, Negative Genetic
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 2 1 2 Negative Genetic, Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 2 Negative Genetic, Negative Genetic
MAK3 YPR051W Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) genetic 2 1 2 Negative Genetic, Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
CRP1 YHR146W Protein that binds to cruciform DNA structures genetic 2 1 2 Positive Genetic, Positive Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 2 1 2 Positive Genetic, Positive Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
ZDS2 YML109W Protein with a role in regulating Swe1p-dependent polarized growth genetic 2 2 1 Phenotypic Enhancement, Phenotypic Suppression
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains physical 2 2 1 Two-hybrid, Reconstituted Complex
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 2 2 1 Synthetic Rescue, Phenotypic Enhancement
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 2 2 1 Synthetic Growth Defect, Negative Genetic
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
VPS21 YOR089C Endosomal Rab family GTPase genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SAS4 YDR181C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SKI3 YPR189W Ski complex component and TPR protein genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type genetic 2 2 1 Synthetic Growth Defect, Negative Genetic
DPH2 YKL191W Protein required for synthesis of diphthamide genetic 2 2 1 Synthetic Growth Defect, Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 2 2 1 Phenotypic Suppression, Phenotypic Enhancement
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
RRP6 YOR001W Nuclear exosome exonuclease component genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 2 1 1 Negative Genetic, Negative Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 2 1 1 Negative Genetic, Negative Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 2 1 1 Negative Genetic, Negative Genetic
PRI2 YKL045W Subunit of DNA primase genetic 2 1 1 Negative Genetic, Negative Genetic
CDC45 YLR103C DNA replication initiation factor genetic 2 1 1 Negative Genetic, Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Negative Genetic, Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 2 1 1 Negative Genetic, Negative Genetic
RAD61 YDR014W Subunit of a complex that inhibits sister chromatid cohesion genetic 2 1 1 Negative Genetic, Negative Genetic
INA17 YPL099C F1F0 ATPase synthase peripheral stalk assembly factor genetic 2 1 1 Negative Genetic, Negative Genetic
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IPL1 YPL209C Aurora kinase of chromosomal passenger complex regulation 1 1 1 protein kinase assay evidence
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A regulation 1 1 1 qualitative western immunoblotting evidence
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ABD1 YBR236C Methyltransferase genetic 1 1 1 Negative Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 1 1 1 Synthetic Growth Defect
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Positive Genetic
BAT1 YHR208W Mitochondrial branched-chain amino acid (BCAA) aminotransferase physical 1 1 1 Affinity Capture-MS
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 1 1 1 Synthetic Rescue
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Synthetic Rescue
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP physical 1 1 1 Affinity Capture-MS
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Biochemical Activity
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
ECM10 YEL030W Heat shock protein of the Hsp70 family physical 1 1 1 Affinity Capture-MS
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Affinity Capture-MS
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 1 1 1 Two-hybrid
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains genetic 1 1 1 Synthetic Growth Defect
FUN12 YAL035W Translation initiation factor eIF5B physical 1 1 1 Two-hybrid
SPC110 YDR356W Inner plaque spindle pole body (SPB) component physical 1 1 1 Co-purification
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 1 1 1 Affinity Capture-MS
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Synthetic Lethality
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis physical 1 1 1 Biochemical Activity
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
PRK1 YIL095W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
PRR2 YDL214C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
RCK1 YGL158W Protein kinase involved in oxidative stress response physical 1 1 1 Biochemical Activity
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Biochemical Activity
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Negative Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
YPL150W YPL150W Protein kinase of unknown cellular role physical 1 1 1 Biochemical Activity
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation physical 1 1 1 Biochemical Activity
HSL1 YKL101W Nim1p-related protein kinase physical 1 1 1 Reconstituted Complex
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase physical 1 1 1 Reconstituted Complex
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-Western
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-Western
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-Western
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, physical 1 1 1 Affinity Capture-Western
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A physical 1 1 1 Biochemical Activity
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A physical 1 1 1 Biochemical Activity
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Phenotypic Enhancement
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex physical 1 1 1 Biochemical Activity
IPL1 YPL209C Aurora kinase of chromosomal passenger complex physical 1 1 1 Biochemical Activity
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Synthetic Growth Defect
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member physical 1 1 1 Affinity Capture-MS
NHP6B YBR089C-A High-mobility group (HMG) protein physical 1 1 1 Affinity Capture-MS
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Dosage Rescue
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Dosage Rescue
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Dosage Rescue
RQC1 YDR333C Component of the ribosome quality control complex (RQC) genetic 1 1 1 Dosage Rescue
CYC8 YBR112C General transcriptional co-repressor genetic 1 1 1 Dosage Rescue
GBP2 YCL011C Poly(A+) RNA-binding protein genetic 1 1 1 Phenotypic Suppression
LCD1 YDR499W Essential protein required for the DNA integrity checkpoint pathways genetic 1 1 1 Phenotypic Suppression
MGS1 YNL218W Protein with DNA-dependent ATPase and ssDNA annealing activities genetic 1 1 1 Dosage Lethality
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 1 1 1 Synthetic Growth Defect
PSY2 YNL201C Subunit of protein phosphatase PP4 complex genetic 1 1 1 Synthetic Growth Defect
SML1 YML058W Ribonucleotide reductase inhibitor genetic 1 1 1 Synthetic Rescue
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Synthetic Growth Defect
CPA2 YJR109C Large subunit of carbamoyl phosphate synthetase genetic 1 1 1 Synthetic Rescue
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Synthetic Rescue
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase genetic 1 1 1 Synthetic Rescue
OAZ1 YPL052W Regulator of ornithine decarboxylase Spe1p genetic 1 1 1 Synthetic Rescue
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Synthetic Rescue
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Synthetic Rescue
SPH1 YLR313C Protein involved in shmoo formation and bipolar bud site selection genetic 1 1 1 Synthetic Rescue
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Synthetic Rescue
RTC2 YBR147W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Synthetic Rescue
RTC3 YHR087W Protein of unknown function involved in RNA metabolism genetic 1 1 1 Synthetic Rescue
RTC4 YNL254C Protein of unknown function genetic 1 1 1 Synthetic Rescue
RTC5 YOR118W Protein of unknown function genetic 1 1 1 Synthetic Rescue
RTC6 YPL183W-A Protein involved in translation genetic 1 1 1 Synthetic Rescue
YGR201C YGR201C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Synthetic Rescue
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Rescue
COQ10 YOL008W Coenzyme Q (ubiquinone) binding protein genetic 1 1 1 Synthetic Rescue
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Synthetic Rescue
COX17 YLL009C Copper metallochaperone that transfers copper to Sco1p and Cox11p genetic 1 1 1 Synthetic Rescue
CYT2 YKL087C Cytochrome c1 heme lyase genetic 1 1 1 Synthetic Rescue
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Synthetic Rescue
EMI1 YDR512C Non-essential protein of unknown function genetic 1 1 1 Synthetic Rescue
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Synthetic Rescue
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Synthetic Rescue
FUM1 YPL262W Fumarase genetic 1 1 1 Synthetic Rescue
FYV12 YOR183W Protein of unknown function genetic 1 1 1 Synthetic Rescue
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Synthetic Rescue
GPD2 YOL059W NAD-dependent glycerol 3-phosphate dehydrogenase genetic 1 1 1 Synthetic Rescue
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Synthetic Rescue
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Synthetic Rescue
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Synthetic Rescue
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Synthetic Rescue
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Synthetic Rescue
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Synthetic Rescue
IRC7 YFR055W Cysteine desulphydrase, enables growth on cysteine as nitrogen source genetic 1 1 1 Synthetic Rescue
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Synthetic Rescue
KEL1 YHR158C Protein required for proper cell fusion and cell morphology genetic 1 1 1 Synthetic Rescue
KHA1 YJL094C Putative K+/H+ antiporter genetic 1 1 1 Synthetic Rescue
LAC1 YKL008C Ceramide synthase component genetic 1 1 1 Synthetic Rescue
LCB3 YJL134W Long-chain base-1-phosphate phosphatase genetic 1 1 1 Synthetic Rescue
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Synthetic Rescue
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator genetic 1 1 1 Synthetic Rescue
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA genetic 1 1 1 Synthetic Rescue
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 1 1 1 Synthetic Rescue
MLH2 YLR035C Protein involved in mismatch repair and meiotic recombination genetic 1 1 1 Synthetic Rescue
MSN4 YKL062W Stress-responsive transcriptional activator genetic 1 1 1 Synthetic Rescue
MSS18 YPR134W Nuclear encoded protein needed for splicing of mitochondrial intron genetic 1 1 1 Synthetic Rescue
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Synthetic Rescue
NMD4 YLR363C Protein that may be involved in nonsense-mediated mRNA decay genetic 1 1 1 Synthetic Rescue
NPR1 YNL183C Protein kinase genetic 1 1 1 Synthetic Rescue
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Synthetic Rescue
PCT1 YGR202C Cholinephosphate cytidylyltransferase genetic 1 1 1 Synthetic Rescue
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Synthetic Rescue
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs genetic 1 1 1 Synthetic Rescue
PEX13 YLR191W Peroxisomal importomer complex component genetic 1 1 1 Synthetic Rescue
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein genetic 1 1 1 Synthetic Rescue
PEX22 YAL055W Putative peroxisomal membrane protein genetic 1 1 1 Synthetic Rescue
PEX3 YDR329C Peroxisomal membrane protein (PMP) genetic 1 1 1 Synthetic Rescue
PEX4 YGR133W Peroxisomal ubiquitin conjugating enzyme genetic 1 1 1 Synthetic Rescue
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Synthetic Rescue
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein genetic 1 1 1 Synthetic Rescue
PHO87 YCR037C Low-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Synthetic Rescue
PKH3 YDR466W Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p genetic 1 1 1 Synthetic Rescue
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane genetic 1 1 1 Synthetic Rescue
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 1 1 1 Synthetic Rescue
PRS4 YBL068W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP genetic 1 1 1 Synthetic Rescue
PUF6 YDR496C Pumilio-homology domain protein genetic 1 1 1 Synthetic Rescue
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Synthetic Rescue
RHO4 YKR055W Non-essential small GTPase genetic 1 1 1 Synthetic Rescue
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Synthetic Rescue
RNR3 YIL066C Minor isoform of large subunit of ribonucleotide-diphosphate reductase genetic 1 1 1 Synthetic Rescue
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Synthetic Rescue
RPL19A YBR084C-A Ribosomal 60S subunit protein L19A genetic 1 1 1 Synthetic Rescue
RPL31B YLR406C Ribosomal 60S subunit protein L31B genetic 1 1 1 Synthetic Rescue
RPL33B YOR234C Ribosomal 60S subunit protein L33B genetic 1 1 1 Synthetic Rescue
RPL34A YER056C-A Ribosomal 60S subunit protein L34A genetic 1 1 1 Synthetic Rescue
RPL4A YBR031W Ribosomal 60S subunit protein L4A genetic 1 1 1 Synthetic Rescue
RTR1 YER139C Dual specificity protein phosphatase genetic 1 1 1 Synthetic Rescue
SAM1 YLR180W S-adenosylmethionine synthetase genetic 1 1 1 Synthetic Rescue
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane genetic 1 1 1 Synthetic Rescue
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome genetic 1 1 1 Synthetic Rescue
SKP2 YNL311C F-box protein of unknown function genetic 1 1 1 Synthetic Rescue
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Synthetic Rescue
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Synthetic Rescue
SQS1 YNL224C Protein that stimulates the ATPase and helicase activities of Prp43p genetic 1 1 1 Synthetic Rescue
SSH1 YBR283C Subunit of the Ssh1 translocon complex genetic 1 1 1 Synthetic Rescue
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Synthetic Rescue
TIR3 YIL011W Cell wall mannoprotein genetic 1 1 1 Synthetic Rescue
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease genetic 1 1 1 Synthetic Rescue
TOM7 YNL070W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Synthetic Rescue
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Synthetic Rescue
TPM2 YIL138C Minor isoform of tropomyosin genetic 1 1 1 Synthetic Rescue
TRM44 YPL030W tRNA(Ser) Um(44) 2'-O-methyltransferase genetic 1 1 1 Synthetic Rescue
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Synthetic Rescue
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Synthetic Rescue
UBX7 YBR273C UBX (ubiquitin regulatory X) domain-containing protein genetic 1 1 1 Synthetic Rescue
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Synthetic Rescue
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Synthetic Rescue
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Synthetic Rescue
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Synthetic Rescue
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Synthetic Rescue
VPS60 YDR486C Protein involved in late endosome to vacuole transport genetic 1 1 1 Synthetic Rescue
XBP1 YIL101C Transcriptional repressor genetic 1 1 1 Synthetic Rescue
YKE4 YIL023C Zinc transporter genetic 1 1 1 Synthetic Rescue
YPS7 YDR349C Putative GPI-anchored aspartic protease genetic 1 1 1 Synthetic Rescue
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Synthetic Lethality
SLZ1 YNL196C Sporulation-specific protein with a leucine zipper motif genetic 1 1 1 Synthetic Lethality
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Synthetic Lethality
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Synthetic Lethality
FYV4 YHR059W Protein of unknown function genetic 1 1 1 Synthetic Lethality
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Synthetic Lethality
HEF3 YNL014W Translational elongation factor EF-3 genetic 1 1 1 Synthetic Lethality
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Synthetic Lethality
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 1 1 1 Synthetic Lethality
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Synthetic Lethality
PBI2 YNL015W Cytosolic inhibitor of vacuolar proteinase B (PRB1) genetic 1 1 1 Synthetic Lethality
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Synthetic Lethality
RPL19B YBL027W Ribosomal 60S subunit protein L19B genetic 1 1 1 Synthetic Lethality
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Lethality
RTT106 YNL206C Histone chaperone genetic 1 1 1 Synthetic Lethality
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Synthetic Lethality
WHI3 YNL197C RNA binding protein that modulates mRNA stability genetic 1 1 1 Synthetic Lethality
YME2 YMR302C Integral inner mitochondrial membrane protein genetic 1 1 1 Synthetic Lethality
MTC2 YKL098W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MTC3 YGL226W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MTC4 YBR255W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MTC6 YHR151C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YDL218W YDL218W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
DTD1 YDL219W D-Tyr-tRNA(Tyr) deacylase genetic 1 1 1 Synthetic Growth Defect
FMP45 YDL222C Integral membrane protein localized to mitochondria genetic 1 1 1 Synthetic Growth Defect
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking genetic 1 1 1 Synthetic Growth Defect
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Synthetic Growth Defect
KEL2 YGR238C Protein that negatively regulates mitotic exit genetic 1 1 1 Synthetic Growth Defect
MRP49 YKL167C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Synthetic Growth Defect
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
TIF2 YJL138C Translation initiation factor eIF4A genetic 1 1 1 Synthetic Growth Defect
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Synthetic Growth Defect
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane genetic 1 1 1 Synthetic Growth Defect
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Synthetic Growth Defect
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Synthetic Growth Defect
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Growth Defect
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Synthetic Growth Defect
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Synthetic Growth Defect
EST2 YLR318W Reverse transcriptase subunit of the telomerase holoenzyme genetic 1 1 1 Synthetic Growth Defect
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Synthetic Growth Defect
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Synthetic Growth Defect
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Synthetic Growth Defect
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 1 1 1 Synthetic Growth Defect
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 1 1 1 Synthetic Growth Defect
INO2 YDR123C Transcription factor genetic 1 1 1 Synthetic Growth Defect
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Synthetic Growth Defect
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Synthetic Growth Defect
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Synthetic Growth Defect
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Synthetic Growth Defect
NFU1 YKL040C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 1 1 1 Synthetic Growth Defect
OAC1 YKL120W Mitochondrial inner membrane transporter genetic 1 1 1 Synthetic Growth Defect
PDX1 YGR193C E3-binding protein of the mitochondrial pyruvate dehydrogenase complex genetic 1 1 1 Synthetic Growth Defect
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Synthetic Growth Defect
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Synthetic Growth Defect
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Synthetic Growth Defect
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Synthetic Growth Defect
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Synthetic Growth Defect
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Synthetic Growth Defect
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 1 1 1 Synthetic Growth Defect
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Synthetic Growth Defect
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Synthetic Growth Defect
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Synthetic Growth Defect
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Synthetic Growth Defect
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways genetic 1 1 1 Synthetic Growth Defect
SIR1 YKR101W Protein involved in silencing at mating-type loci HML and HMR genetic 1 1 1 Synthetic Growth Defect
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Synthetic Growth Defect
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Synthetic Growth Defect
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Synthetic Growth Defect
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Synthetic Growth Defect
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Synthetic Rescue
MAE1 YKL029C Mitochondrial malic enzyme genetic 1 1 1 Synthetic Rescue
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Phenotypic Enhancement
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
TOP2 YNL088W Topoisomerase II genetic 1 1 1 Phenotypic Enhancement
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Phenotypic Suppression
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Phenotypic Enhancement
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Synthetic Rescue
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Synthetic Rescue
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins genetic 1 1 1 Synthetic Growth Defect
IRA1 YBR140C GTPase-activating protein genetic 1 1 1 Synthetic Growth Defect
RMI1 YPL024W Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex genetic 1 1 1 Synthetic Growth Defect
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 1 1 1 Phenotypic Suppression
CYR1 YJL005W Adenylate cyclase genetic 1 1 1 Phenotypic Enhancement
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Synthetic Lethality
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Synthetic Growth Defect
PUF4 YGL014W Member of the PUF protein family genetic 1 1 1 Negative Genetic
PTC6 YCR079W Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
MAK10 YEL053C Non-catalytic subunit of the NatC N-terminal acetyltransferase genetic 1 1 1 Negative Genetic
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Negative Genetic
DPH1 YIL103W Protein required for synthesis of diphthamide genetic 1 1 1 Negative Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Negative Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Negative Genetic
PPT1 YGR123C Protein serine/threonine phosphatase genetic 1 1 1 Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
HSP104 YLL026W Disaggregase genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
JJJ3 YJR097W Iron-binding protein genetic 1 1 1 Negative Genetic
HGH1 YGR187C Chaperone protein for translation factor eEF2 genetic 1 1 1 Negative Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 1 1 1 Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
FKH1 YIL131C Forkhead family transcription factor genetic 1 1 1 Negative Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
PHO13 YDL236W Conserved phosphatase acting as a metabolite repair enzyme genetic 1 1 1 Negative Genetic
TMA19 YKL056C Protein that associates with ribosomes genetic 1 1 1 Negative Genetic
PTC2 YER089C Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MBP1 YDL056W Transcription factor genetic 1 1 1 Negative Genetic
SDD2 YMR074C Protein with homology to human PDCD5 genetic 1 1 1 Negative Genetic
DBR1 YKL149C RNA lariat debranching enzyme genetic 1 1 1 Negative Genetic
TIP41 YPR040W Tap42p-interacting protein genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
RRN10 YBL025W Protein involved in promoting high level transcription of rDNA genetic 1 1 1 Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Negative Genetic
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Negative Genetic
CSM3 YMR048W Replication fork associated factor genetic 1 1 1 Negative Genetic
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
PAN2 YGL094C Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 1 1 1 Negative Genetic
IBD2 YNL164C Component of the BUB2-dependent spindle checkpoint pathway genetic 1 1 1 Negative Genetic
DPH6 YLR143W Diphthamide synthetase genetic 1 1 1 Negative Genetic
TMH18 YPR098C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF genetic 1 1 1 Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Negative Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 1 1 1 Negative Genetic
GSH2 YOL049W Glutathione synthetase genetic 1 1 1 Positive Genetic
SYS1 YJL004C Integral membrane protein of the Golgi genetic 1 1 1 Positive Genetic
TRP1 YDR007W Phosphoribosylanthranilate isomerase genetic 1 1 1 Positive Genetic
RAD23 YEL037C Protein with ubiquitin-like N terminus genetic 1 1 1 Positive Genetic
FCY2 YER056C Purine-cytosine permease genetic 1 1 1 Positive Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Positive Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Positive Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Positive Genetic
YJL206C YJL206C Putative protein of unknown function genetic 1 1 1 Positive Genetic
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 1 1 1 Positive Genetic
COX12 YLR038C Subunit VIb of cytochrome c oxidase genetic 1 1 1 Positive Genetic
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 1 1 1 Positive Genetic
RPL24B YGR148C Ribosomal 60S subunit protein L24B genetic 1 1 1 Positive Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
RPL36A YMR194W Ribosomal 60S subunit protein L36A genetic 1 1 1 Positive Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Positive Genetic
MCX1 YBR227C Non-proteolytic ATPase of the AAA family genetic 1 1 1 Positive Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Positive Genetic
PHO2 YDL106C Homeobox transcription factor genetic 1 1 1 Positive Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Positive Genetic
SIM1 YIL123W Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) genetic 1 1 1 Positive Genetic
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 1 1 1 Positive Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Positive Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 genetic 1 1 1 Positive Genetic
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein genetic 1 1 1 Positive Genetic
SNX4 YJL036W Sorting nexin genetic 1 1 1 Positive Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Positive Genetic
RPL42A YNL162W Ribosomal 60S subunit protein L42A genetic 1 1 1 Positive Genetic
NRG2 YBR066C Transcriptional repressor genetic 1 1 1 Positive Genetic
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 1 1 1 Positive Genetic
RPL16A YIL133C Ribosomal 60S subunit protein L16A genetic 1 1 1 Positive Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Positive Genetic
RPL24A YGL031C Ribosomal 60S subunit protein L24A genetic 1 1 1 Positive Genetic
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Positive Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Positive Genetic
PFK26 YIL107C 6-phosphofructo-2-kinase genetic 1 1 1 Positive Genetic
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Positive Genetic
RPL27B YDR471W Ribosomal 60S subunit protein L27B genetic 1 1 1 Positive Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Positive Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Positive Genetic
RPO41 YFL036W Mitochondrial RNA polymerase genetic 1 1 1 Positive Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Positive Genetic
PCP1 YGR101W Mitochondrial serine protease genetic 1 1 1 Positive Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Positive Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Positive Genetic
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 1 1 1 Positive Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Positive Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Positive Genetic
RPL35B YDL136W Ribosomal 60S subunit protein L35B genetic 1 1 1 Positive Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Positive Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Positive Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Positive Genetic
RPP1B YDL130W Ribosomal protein P1 beta genetic 1 1 1 Positive Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Positive Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Positive Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Lethality
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Synthetic Rescue
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Positive Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Positive Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Positive Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Positive Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Positive Genetic
GAL10 YBR019C UDP-glucose-4-epimerase genetic 1 1 1 Positive Genetic
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Positive Genetic
YFH7 YFR007W Putative kinase with similarity to the PRK/URK/PANK kinase subfamily genetic 1 1 1 Positive Genetic
FAR7 YFR008W Protein involved in recovery from pheromone-induced cell cycle arrest genetic 1 1 1 Positive Genetic
URA1 YKL216W Dihydroorotate dehydrogenase genetic 1 1 1 Positive Genetic
GAL2 YLR081W Galactose permease genetic 1 1 1 Positive Genetic
VAC14 YLR386W Enzyme regulator genetic 1 1 1 Positive Genetic
TEP1 YNL128W PTEN homolog with no demonstrated inositol lipid phosphatase activity genetic 1 1 1 Positive Genetic
SDH5 YOL071W Protein required for flavinylation of Sdh1p genetic 1 1 1 Positive Genetic
MCA1 YOR197W Ca2+-dependent cysteine protease genetic 1 1 1 Positive Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Positive Genetic
SSP2 YOR242C Sporulation specific protein that localizes to the spore wall genetic 1 1 1 Positive Genetic
YPK9 YOR291W Vacuolar protein with a possible role in sequestering heavy metals genetic 1 1 1 Positive Genetic
PSO2 YMR137C Nuclease required for DNA single- and double-strand break repair genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
SLD5 YDR489W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 1 1 1 Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 1 1 1 Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Negative Genetic
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
SRB7 YDR308C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Negative Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
GPI14 YJR013W Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
URA6 YKL024C Uridylate kinase genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
RPC19 YNL113W RNA polymerase subunit AC19 genetic 1 1 1 Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Negative Genetic
PUP1 YOR157C Beta 2 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 1 1 1 Negative Genetic
TAF3 YPL011C TFIID subunit (47 kDa) genetic 1 1 1 Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
URA7 YBL039C Major CTP synthase isozyme (see also URA8) genetic 1 1 1 Negative Genetic
NPL4 YBR170C Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
SYP1 YCR030C Negative regulator of WASP-Arp23 complex genetic 1 1 1 Negative Genetic
SOL2 YCR073W-A Protein with a possible role in tRNA export genetic 1 1 1 Negative Genetic
RAD55 YDR076W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
MKC7 YDR144C GPI-anchored aspartyl protease genetic 1 1 1 Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Negative Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
DSE1 YER124C Daughter cell-specific protein genetic 1 1 1 Negative Genetic
YER137C YER137C Protein of unknown function genetic 1 1 1 Negative Genetic
EMP65 YER140W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
SPI1 YER150W GPI-anchored cell wall protein involved in weak acid resistance genetic 1 1 1 Negative Genetic
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Negative Genetic
MSH4 YFL003C Protein involved in meiotic recombination genetic 1 1 1 Negative Genetic
YBP2 YGL060W Central kinetochore associated protein genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Negative Genetic
SCM4 YGR049W Mitochondrial outer membrane protein of unknown function genetic 1 1 1 Negative Genetic
ECM34 YHL043W Protein of unknown function genetic 1 1 1 Negative Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
ERC1 YHR032W Member of the multi-drug and toxin extrusion (MATE) family genetic 1 1 1 Negative Genetic
PUT2 YHR037W Delta-1-pyrroline-5-carboxylate dehydrogenase genetic 1 1 1 Negative Genetic
TOM71 YHR117W Mitochondrial outer membrane protein genetic 1 1 1 Negative Genetic
PEX28 YHR150W Peroxisomal integral membrane peroxin genetic 1 1 1 Negative Genetic
SPO12 YHR152W Nucleolar protein of unknown function genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Negative Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Negative Genetic
NAS2 YIL007C Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 1 1 1 Negative Genetic
IRC18 YJL037W Protein involved in outer spore wall assembly genetic 1 1 1 Negative Genetic
IME1 YJR094C Master regulator of meiosis that is active only during meiotic events genetic 1 1 1 Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 1 1 1 Negative Genetic
PRR1 YKL116C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
YRA2 YKL214C Member of the REF (RNA and export factor binding proteins) family genetic 1 1 1 Negative Genetic
UTP30 YKR060W Subunit of U3-containing 90S preribosome complex genetic 1 1 1 Negative Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 1 1 1 Negative Genetic
YLL032C YLL032C Protein of unknown function genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Negative Genetic
CSI1 YMR025W Subunit of the Cop9 signalosome genetic 1 1 1 Negative Genetic
SPO1 YNL012W Meiosis-specific prospore protein genetic 1 1 1 Negative Genetic
HHF2 YNL030W Histone H4 genetic 1 1 1 Negative Genetic
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SWM2 YNR004W Protein with a role in snRNA and snoRNA cap trimethylation genetic 1 1 1 Negative Genetic
COQ2 YNR041C Para hydroxybenzoate polyprenyl transferase genetic 1 1 1 Negative Genetic
RFM1 YOR279C Component of the Sum1p-Rfm1p-Hst1p complex genetic 1 1 1 Negative Genetic
YOR342C YOR342C Protein of unknown function genetic 1 1 1 Negative Genetic
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
ELC1 YPL046C Elongin C, conserved among eukaryotes genetic 1 1 1 Negative Genetic
CWC27 YPL064C Component of a complex containing Cef1p genetic 1 1 1 Negative Genetic
CQD1 YPL109C UbiB family mitochondrial protein genetic 1 1 1 Negative Genetic
YPL245W YPL245W Putative protein of unknown function genetic 1 1 1 Negative Genetic
PHO11 YAR071W One of three repressible acid phosphatases genetic 1 1 1 Negative Genetic
PET112 YBL080C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
MRPL37 YBR268W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MFB1 YDR219C Mitochondria-associated F-box protein genetic 1 1 1 Negative Genetic
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRP1 YDR347W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
MRP20 YDR405W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL28 YDR462W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRX1 YER077C Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
TRP2 YER090W Anthranilate synthase genetic 1 1 1 Negative Genetic
PNC1 YGL037C Nicotinamidase that converts nicotinamide to nicotinic acid genetic 1 1 1 Negative Genetic
ROG1 YGL144C Lipase with specificity for monoacylglycerol genetic 1 1 1 Negative Genetic
MUP1 YGR055W High affinity methionine permease genetic 1 1 1 Negative Genetic
YHL042W YHL042W Endoplasmic reticulum protein genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
YJL136W-A YJL136W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Negative Genetic
SAG1 YJR004C Alpha-agglutinin of alpha-cells genetic 1 1 1 Negative Genetic
LIH1 YJR107W Putative lipase genetic 1 1 1 Negative Genetic
THI11 YJR156C Protein involved in synthesis of the thiamine precursor HMP genetic 1 1 1 Negative Genetic
YKL106C-A YKL106C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
MEF1 YLR069C Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
MAG2 YLR427W Cytoplasmic protein of unknown function genetic 1 1 1 Negative Genetic
GAL80 YML051W Transcriptional regulator involved in the repression of GAL genes genetic 1 1 1 Negative Genetic
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Negative Genetic
INP2 YMR163C Peroxisome-specific receptor important for peroxisome inheritance genetic 1 1 1 Negative Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
UAF30 YOR295W Subunit of UAF (upstream activation factor) complex genetic 1 1 1 Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
RNY1 YPL123C Vacuolar RNase of the T(2) family genetic 1 1 1 Negative Genetic
YIG1 YPL201C Protein that interacts with glycerol 3-phosphatase genetic 1 1 1 Negative Genetic
CTR1 YPR124W High-affinity copper transporter of plasma membrane genetic 1 1 1 Negative Genetic
REV3 YPL167C Catalytic subunit of DNA polymerase zeta genetic 1 1 1 Phenotypic Suppression
UNG1 YML021C Uracil-DNA glycosylase genetic 1 1 1 Phenotypic Enhancement
MIH1 YMR036C Protein tyrosine phosphatase genetic 1 1 1 Phenotypic Suppression
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor genetic 1 1 1 Synthetic Rescue
VPS36 YLR417W Component of the ESCRT-II complex genetic 1 1 1 Synthetic Rescue
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
YEN1 YER041W Holliday junction resolvase genetic 1 1 1 Synthetic Growth Defect
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Synthetic Growth Defect
SLX1 YBR228W Endonuclease involved in DNA recombination and repair genetic 1 1 1 Synthetic Growth Defect
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Synthetic Growth Defect
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SAE2 YGL175C Endonuclease required for telomere elongation genetic 1 1 1 Phenotypic Suppression
AKL1 YBR059C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
BOL2 YGL220W Cytosolic protein involved in repression of iron regulon transcription genetic 1 1 1 Negative Genetic
AMF1 YOR378W Low affinity NH4+ transporter genetic 1 1 1 Negative Genetic
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV physical 1 1 1 Affinity Capture-MS
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Synthetic Rescue
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Synthetic Growth Defect
ALD5 YER073W Mitochondrial aldehyde dehydrogenase genetic 1 1 1 Synthetic Rescue
ADE6 YGR061C Formylglycinamidine-ribonucleotide (FGAM)-synthetase genetic 1 1 1 Negative Genetic
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Synthetic Growth Defect
CAK1 YFL029C Cyclin-dependent kinase-activating kinase physical 1 1 1 Reconstituted Complex
BMT2 YBR141C Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins genetic 1 1 1 Negative Genetic
APC9 YLR102C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Growth Defect
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 1 1 1 Synthetic Growth Defect
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Rescue
BCS1 YDR375C Protein translocase and chaperone required for Complex III assembly genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Positive Genetic
ARO8 YGL202W Aromatic aminotransferase I genetic 1 1 1 Positive Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
ALD6 YPL061W Cytosolic aldehyde dehydrogenase genetic 1 1 1 Synthetic Rescue
AQY3 YFL054C Putative channel-like protein genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
AIM29 YKR074W Protein of unknown function genetic 1 1 1 Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Synthetic Growth Defect
BNA2 YJR078W Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase genetic 1 1 1 Synthetic Rescue
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Positive Genetic
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 1 1 1 Positive Genetic
AGC1 YPR021C Mitochondrial amino acid transporter genetic 1 1 1 Negative Genetic
AIM10 YER087W Protein with similarity to tRNA synthetases genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Synthetic Rescue
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Synthetic Growth Defect