Standard name Systematic name Name description Description
NPL3 YDR432W RNA-binding protein RNA-binding protein; promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; represses translation initiation by binding eIF4G; required for pre-mRNA splicing; interacts with E3 ubiquitin ligase Bre1p, linking histone ubiquitination to mRNA processing; may have role in telomere maintenance; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in cytoplasm; protein abundance increases in response to DNA replication stress
Visualize the interactome of NPL3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.252 0.121 0.303
Nucleus 0.796 0.757 0.624
Cytoplasm NaN 0.214 0.092
Vac/Vac Memb NaN 0.058 NaN
Mito NaN NaN 0.073

GFP localization & abundance

GFP localization GFP abundance
nucleus 78700

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NPL3 12 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 15 6 13 Two-hybrid, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Affinity Capture-Western, Biochemical Activity, Affinity Capture-MS, Biochemical Activity, Biochemical Activity, PCA, Biochemical Activity, Reconstituted Complex, Biochemical Activity
NPL3 YDR432W RNA-binding protein physical 9 5 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Far Western, Two-hybrid, Two-hybrid, Reconstituted Complex, Reconstituted Complex
SKY1 YMR216C SR protein kinase (SRPK) physical 8 2 7 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, Biochemical Activity, Reconstituted Complex, Biochemical Activity
GAL10 YBR019C UDP-glucose-4-epimerase genetic 6 3 5 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue, Synthetic Growth Defect
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export physical 6 3 4 Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
MTR10 YOR160W Nuclear import receptor physical 6 2 4 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex physical 5 2 5 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex physical 5 2 5 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 5 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 5 2 5 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Dosage Rescue
RRP6 YOR001W Nuclear exosome exonuclease component genetic 5 4 4 Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Rescue, Synthetic Rescue
SNP1 YIL061C Component of U1 snRNP required for mRNA splicing via spliceosome physical 4 3 4 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
MUD1 YBR119W U1 snRNP A protein physical 4 4 3 Affinity Capture-Western, Co-localization, Affinity Capture-MS, Reconstituted Complex
MTR10 YOR160W Nuclear import receptor genetic 4 3 3 Synthetic Lethality, Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue
AIR1 YIL079C Zinc knuckle protein physical 4 3 3 Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 4 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit genetic 4 3 1 Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect, Dosage Rescue
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 3 3 3 Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex genetic 3 3 3 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 3 3 3 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome genetic 3 3 3 Negative Genetic, Synthetic Lethality, Synthetic Growth Defect
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid
RNH1 YMR234W Ribonuclease H1 genetic 3 2 3 Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 3 2 3 Synthetic Lethality, Negative Genetic, Synthetic Lethality
GBP2 YCL011C Poly(A+) RNA-binding protein physical 3 2 3 Two-hybrid, Affinity Capture-MS, Two-hybrid
MUD2 YKL074C Protein involved in early pre-mRNA splicing physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 3 2 3 Negative Genetic, Synthetic Lethality, Synthetic Lethality
SKY1 YMR216C SR protein kinase (SRPK) regulation 3 1 3 protein kinase assay evidence, protein kinase assay evidence, protein kinase assay evidence
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RAD52 YML032C Protein involved in homologous recombination genetic 3 1 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 3 3 2 Biochemical Activity, Reconstituted Complex, Protein-peptide
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome genetic 3 3 2 Negative Genetic, Synthetic Rescue, Synthetic Growth Defect
BRE1 YDL074C E3 ubiquitin ligase genetic 3 2 2 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 3 2 2 Positive Genetic, Synthetic Rescue, Synthetic Rescue
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 3 2 2 Positive Genetic, Synthetic Rescue, Synthetic Rescue
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 3 2 2 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
SPP1 YPL138C Subunit of COMPASS (Set1C) genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 3 2 2 Positive Genetic, Synthetic Rescue, Synthetic Rescue
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 3 1 2 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
FUN12 YAL035W Translation initiation factor eIF5B genetic 3 3 1 Synthetic Lethality, Dosage Rescue, Phenotypic Suppression
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 3 3 1 Synthetic Growth Defect, Dosage Rescue, Phenotypic Suppression
CDC73 YLR418C Component of the Paf1p complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
LSM1 YJL124C Lsm (Like Sm) protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export physical 2 2 2 Two-hybrid, Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
THP2 YHR167W Subunit of the THO and TREX complexes genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 2 2 2 Affinity Capture-MS, Protein-peptide
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 2 2 2 Negative Genetic, Synthetic Lethality
RPS2 YGL123W Protein component of the small (40S) subunit physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 2 2 2 Synthetic Lethality, Synthetic Rescue
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PML1 YLR016C Subunit of the RES complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Synthetic Rescue
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SKI3 YPR189W Ski complex component and TPR protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PUF4 YGL014W Member of the PUF protein family genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SWT1 YOR166C RNA endoribonuclease involved in perinuclear mRNP quality control genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 2 2 Two-hybrid, Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
HRP1 YOL123W Subunit of cleavage factor I physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
HRP1 YOL123W Subunit of cleavage factor I genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
HTZ1 YOL012C Histone variant H2AZ genetic 2 2 2 Negative Genetic, Synthetic Lethality
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 2 2 Positive Genetic, Synthetic Rescue
HSP82 YPL240C Hsp90 chaperone genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
LEA1 YPL213W Component of U2 snRNP complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MSN5 YDR335W Karyopherin genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
EUC1 YMR111C Sequence-specific DNA binding protein genetic 2 2 2 Synthetic Rescue, Synthetic Growth Defect
MPP6 YNR024W Nuclear exosome-associated RNA binding protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
RPB2 YOR151C RNA polymerase II second largest subunit B150 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RAD18 YCR066W E3 ubiquitin ligase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
TSA1 YML028W Thioredoxin peroxidase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ASF1 YJL115W Nucleosome assembly factor genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
HIR1 YBL008W Subunit of the HIR complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MSL5 YLR116W Component of commitment complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component physical 2 2 1 Affinity Capture-Western, Two-hybrid
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export genetic 2 2 1 Phenotypic Suppression, Dosage Rescue
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones physical 2 2 1 Reconstituted Complex, Two-hybrid
PRM9 YAR031W Pheromone-regulated protein genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
RPP2B YDR382W Ribosomal protein P2 beta genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SER1 YOR184W 3-phosphoserine aminotransferase genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SSD1 YDR293C Translational repressor genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
TGL4 YKR089C Multifunctional lipase/hydrolase/phospholipase genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
UGA2 YBR006W Succinate semialdehyde dehydrogenase genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
YLR046C YLR046C Putative membrane protein genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
YDR042C YDR042C Putative protein of unknown function genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
YGK1 YGL101W 5'-deoxynucleotidase genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SLM4 YBR077C Subunit of the EGO/GSE complex genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
YKR041W YKR041W Protein of unknown function genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
THO1 YER063W Conserved nuclear RNA-binding protein genetic 2 2 1 Phenotypic Suppression, Dosage Rescue
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 2 2 1 Phenotypic Suppression, Dosage Rescue
MRPL39 YML009C Mitochondrial ribosomal protein of the large subunit genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
BGL2 YGR282C Endo-beta-1,3-glucanase genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
BOL2 YGL220W Cytosolic protein involved in repression of iron regulon transcription genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
BUL1 YMR275C Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
GAL2 YLR081W Galactose permease genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
MTR2 YKL186C mRNA transport regulator genetic 2 2 1 Phenotypic Suppression, Synthetic Growth Defect
FIG2 YCR089W Cell wall adhesin, expressed specifically during mating genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
DSD1 YGL196W D-serine dehydratase (aka D-serine ammonia-lyase) genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
HPM1 YIL110W AdoMet-dependent methyltransferase genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
LEO1 YOR123C Component of the Paf1 complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease regulation 1 1 1 northern blot evidence
RAD53 YPL153C DNA damage response kinase regulation 1 1 1 protein kinase assay evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription physical 1 1 1 Affinity Capture-MS
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation physical 1 1 1 Affinity Capture-MS
CDC40 YDR364C Pre-mRNA splicing factor physical 1 1 1 Affinity Capture-Western
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 1 1 1 Synthetic Rescue
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase genetic 1 1 1 Positive Genetic
AIM25 YJR100C Mitochondria protein of unknown function genetic 1 1 1 Synthetic Growth Defect
NKP1 YDR383C Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Synthetic Rescue
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Biochemical Activity
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Rescue
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 1 1 1 Affinity Capture-Western
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Negative Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
ECM2 YBR065C Pre-mRNA splicing factor genetic 1 1 1 Synthetic Growth Defect
BRE1 YDL074C E3 ubiquitin ligase physical 1 1 1 Affinity Capture-Western
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Synthetic Rescue
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Synthetic Growth Defect
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 1 1 1 Synthetic Rescue
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly physical 1 1 1 Affinity Capture-Western
KEL3 YPL263C Cytoplasmic protein of unknown function physical 1 1 1 Affinity Capture-MS
KEL3 YPL263C Cytoplasmic protein of unknown function genetic 1 1 1 Synthetic Rescue
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs physical 1 1 1 Affinity Capture-MS
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex physical 1 1 1 Two-hybrid
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
MTR4 YJL050W RNA duplex-sensing translocase physical 1 1 1 Affinity Capture-MS
LSM1 YJL124C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-Western
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus genetic 1 1 1 Positive Genetic
YGR054W YGR054W Eukaryotic initiation factor eIF2A physical 1 1 1 Affinity Capture-MS
SGN1 YIR001C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-Western
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Negative Genetic
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences physical 1 1 1 Two-hybrid
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) physical 1 1 1 Two-hybrid
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold physical 1 1 1 Affinity Capture-MS
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Synthetic Growth Defect
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p physical 1 1 1 Biochemical Activity
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p genetic 1 1 1 Synthetic Rescue
RPB4 YJL140W RNA polymerase II subunit B32 physical 1 1 1 Affinity Capture-Western
THP2 YHR167W Subunit of the THO and TREX complexes physical 1 1 1 Affinity Capture-MS
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Synthetic Lethality
SAC3 YDR159W mRNA export factor physical 1 1 1 Affinity Capture-MS
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 1 1 1 Affinity Capture-MS
SPT6 YGR116W Nucleosome remodeling protein physical 1 1 1 Affinity Capture-MS
THO2 YNL139C Subunit of the THO complex physical 1 1 1 Affinity Capture-MS
THO2 YNL139C Subunit of the THO complex genetic 1 1 1 Synthetic Rescue
RPB5 YBR154C RNA polymerase subunit ABC27 physical 1 1 1 Affinity Capture-MS
SPN1 YPR133C Protein involved in RNA polymerase II transcription physical 1 1 1 Affinity Capture-MS
NRD1 YNL251C RNA-binding subunit of Nrd1 complex physical 1 1 1 Affinity Capture-MS
PRP19 YLL036C Splicing factor associated with the spliceosome physical 1 1 1 Affinity Capture-MS
PUF6 YDR496C Pumilio-homology domain protein physical 1 1 1 Affinity Capture-MS
PUF6 YDR496C Pumilio-homology domain protein genetic 1 1 1 Synthetic Growth Defect
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase physical 1 1 1 Affinity Capture-MS
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
SNU71 YGR013W Component of U1 snRNP required for mRNA splicing via spliceosome physical 1 1 1 Affinity Capture-Western
PRP42 YDR235W U1 snRNP protein involved in splicing physical 1 1 1 Co-localization
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
RRP17 YDR412W 5' exoribonuclease required for 5' end processing of pre-60S rRNA physical 1 1 1 Affinity Capture-MS
SMY2 YBR172C GYF domain protein physical 1 1 1 Affinity Capture-MS
WWM1 YFL010C WW domain containing protein of unknown function physical 1 1 1 Protein-peptide
PRP40 YKL012W U1 snRNP protein involved in splicing physical 1 1 1 Protein-peptide
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Reconstituted Complex
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein genetic 1 1 1 Synthetic Rescue
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-Western
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes physical 1 1 1 Affinity Capture-Western
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Protein-peptide
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
SWD2 YKL018W Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex physical 1 1 1 Affinity Capture-Western
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Affinity Capture-Western
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 1 1 1 Synthetic Growth Defect
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing physical 1 1 1 Reconstituted Complex
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Affinity Capture-Western
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
RPL35A YDL191W Ribosomal 60S subunit protein L35A physical 1 1 1 Affinity Capture-Western
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit genetic 1 1 1 Synthetic Growth Defect
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
PAP2 YOL115W Non-canonical poly(A) polymerase physical 1 1 1 Affinity Capture-MS
TRF5 YNL299W Non-canonical poly(A) polymerase physical 1 1 1 Affinity Capture-MS
RBS1 YDL189W Protein involved in assembly of the RNA Pol III complex physical 1 1 1 Affinity Capture-MS
RTC3 YHR087W Protein of unknown function involved in RNA metabolism genetic 1 1 1 Synthetic Lethality
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Synthetic Lethality
RNA14 YMR061W Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Phenotypic Suppression
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
TRL1 YJL087C tRNA ligase genetic 1 1 1 Negative Genetic
THP1 YOL072W Nuclear pore-associated protein genetic 1 1 1 Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
RLI1 YDR091C Essential Fe-S protein genetic 1 1 1 Positive Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
POP8 YBL018C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Positive Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Synthetic Growth Defect
SAE2 YGL175C Endonuclease required for telomere elongation genetic 1 1 1 Synthetic Growth Defect
RAD51 YER095W Strand exchange protein genetic 1 1 1 Synthetic Growth Defect
RAD55 YDR076W Protein that stimulates strand exchange genetic 1 1 1 Synthetic Growth Defect
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Synthetic Growth Defect
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Synthetic Growth Defect
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Synthetic Growth Defect
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Growth Defect
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Synthetic Lethality
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Synthetic Growth Defect
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Synthetic Growth Defect
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Synthetic Growth Defect
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Synthetic Lethality
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
YOR268C YOR268C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YJL027C YJL027C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
PET18 YCR020C Protein of unknown function genetic 1 1 1 Synthetic Rescue
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein genetic 1 1 1 Synthetic Rescue
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Synthetic Rescue
PGM1 YKL127W Phosphoglucomutase, minor isoform genetic 1 1 1 Synthetic Rescue
PGM2 YMR105C Phosphoglucomutase genetic 1 1 1 Synthetic Rescue
PHA2 YNL316C Prephenate dehydratase genetic 1 1 1 Synthetic Rescue
PHO89 YBR296C Plasma membrane Na+/Pi cotransporter genetic 1 1 1 Synthetic Rescue
PIG1 YLR273C Putative targeting subunit for type-1 protein phosphatase Glc7p genetic 1 1 1 Synthetic Rescue
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Synthetic Rescue
PIP2 YOR363C Autoregulatory, oleate-activated transcription factor genetic 1 1 1 Synthetic Rescue
PLB1 YMR008C Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Synthetic Rescue
PLP1 YDR183W Protein that interacts with CCT (chaperonin containing TCP-1) complex genetic 1 1 1 Synthetic Rescue
PNS1 YOR161C Protein of unknown function genetic 1 1 1 Synthetic Rescue
PNT1 YOR266W Mitochondrial integral inner membrane protein genetic 1 1 1 Synthetic Rescue
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex genetic 1 1 1 Synthetic Rescue
POR2 YIL114C Putative mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Synthetic Rescue
PPM2 YOL141W AdoMet-dependent tRNA methyltransferase genetic 1 1 1 Synthetic Rescue
PRR1 YKL116C Serine/threonine protein kinase genetic 1 1 1 Synthetic Rescue
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase genetic 1 1 1 Synthetic Rescue
PSO2 YMR137C Nuclease required for DNA single- and double-strand break repair genetic 1 1 1 Synthetic Rescue
PTC3 YBL056W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Synthetic Rescue
PTP2 YOR208W Phosphotyrosine-specific phosphatase genetic 1 1 1 Synthetic Rescue
PTP3 YER075C Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Synthetic Rescue
PUF2 YPR042C PUF family mRNA-binding protein genetic 1 1 1 Synthetic Rescue
PUT1 YLR142W Proline oxidase genetic 1 1 1 Synthetic Rescue
PXA1 YPL147W Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p genetic 1 1 1 Synthetic Rescue
PYK2 YOR347C Pyruvate kinase genetic 1 1 1 Synthetic Rescue
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex genetic 1 1 1 Synthetic Rescue
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Synthetic Rescue
QDR3 YBR043C Multidrug transporter of the major facilitator superfamily genetic 1 1 1 Synthetic Rescue
RAD10 YML095C Single-stranded DNA endonuclease (with Rad1p) genetic 1 1 1 Synthetic Rescue
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Synthetic Rescue
RAD16 YBR114W Nucleotide excision repair (NER) protein genetic 1 1 1 Synthetic Rescue
RAD59 YDL059C Protein involved DNA double-strand break repair genetic 1 1 1 Synthetic Rescue
RAX2 YLR084C Protein required for the maintenance of bud site selection genetic 1 1 1 Synthetic Rescue
RBD2 YPL246C Possible rhomboid protease genetic 1 1 1 Synthetic Rescue
RBG1 YAL036C Member of the DRG family of GTP-binding proteins genetic 1 1 1 Synthetic Rescue
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress genetic 1 1 1 Synthetic Rescue
RCN1 YKL159C Protein involved in calcineurin regulation during calcium signaling genetic 1 1 1 Synthetic Rescue
RDH54 YBR073W DNA-dependent ATPase genetic 1 1 1 Synthetic Rescue
REC107 YJR021C Protein involved in early stages of meiotic recombination genetic 1 1 1 Synthetic Rescue
RER1 YCL001W Protein involved in retention of membrane proteins genetic 1 1 1 Synthetic Rescue
REX2 YLR059C 3'-5' RNA exonuclease genetic 1 1 1 Synthetic Rescue
REX3 YLR107W RNA exonuclease genetic 1 1 1 Synthetic Rescue
RGT1 YKL038W Glucose-responsive transcription factor genetic 1 1 1 Synthetic Rescue
RHO4 YKR055W Non-essential small GTPase genetic 1 1 1 Synthetic Rescue
RLM1 YPL089C MADS-box transcription factor genetic 1 1 1 Synthetic Rescue
RME1 YGR044C Zinc finger protein involved in control of meiosis genetic 1 1 1 Synthetic Rescue
ROT2 YBR229C Glucosidase II catalytic subunit genetic 1 1 1 Synthetic Rescue
RPL18B YNL301C Ribosomal 60S subunit protein L18B genetic 1 1 1 Synthetic Rescue
RPL22B YFL034C-A Ribosomal 60S subunit protein L22A genetic 1 1 1 Synthetic Rescue
RPL24A YGL031C Ribosomal 60S subunit protein L24A genetic 1 1 1 Synthetic Rescue
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Synthetic Rescue
RPS14B YJL191W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
RPS28A YOR167C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Rescue
RRI2 YOL117W Subunit of the COP9 signalosome (CSN) complex genetic 1 1 1 Synthetic Rescue
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Synthetic Rescue
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Synthetic Rescue
RSB1 YOR049C Sphingoid long-chain base (LCB) efflux transporter genetic 1 1 1 Synthetic Rescue
RSF2 YJR127C Zinc-finger protein genetic 1 1 1 Synthetic Rescue
RSR1 YGR152C Ras-type GTPase genetic 1 1 1 Synthetic Rescue
SAL1 YNL083W ADP/ATP transporter genetic 1 1 1 Synthetic Rescue
SAM3 YPL274W High-affinity S-adenosylmethionine permease genetic 1 1 1 Synthetic Rescue
SAN1 YDR143C Ubiquitin-protein ligase genetic 1 1 1 Synthetic Rescue
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 1 1 1 Synthetic Rescue
SBE2 YDR351W Protein required for bud growth genetic 1 1 1 Synthetic Rescue
SCJ1 YMR214W One of several homologs of bacterial chaperone DnaJ genetic 1 1 1 Synthetic Rescue
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER genetic 1 1 1 Synthetic Rescue
SCW10 YMR305C Cell wall protein with similarity to glucanases genetic 1 1 1 Synthetic Rescue
SCW4 YGR279C Cell wall protein with similarity to glucanases genetic 1 1 1 Synthetic Rescue
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 1 1 1 Synthetic Rescue
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Synthetic Rescue
SET6 YPL165C SET domain protein of unknown function genetic 1 1 1 Synthetic Rescue
SFC1 YJR095W Mitochondrial succinate-fumarate transporter genetic 1 1 1 Synthetic Rescue
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Synthetic Rescue
SHC1 YER096W Sporulation-specific activator of Chs3p (chitin synthase III) genetic 1 1 1 Synthetic Rescue
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase genetic 1 1 1 Synthetic Rescue
SHR5 YOL110W Palmitoyltransferase subunit genetic 1 1 1 Synthetic Rescue
SIL1 YOL031C Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p genetic 1 1 1 Synthetic Rescue
SIT1 YEL065W Ferrioxamine B transporter genetic 1 1 1 Synthetic Rescue
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Synthetic Rescue
SKN1 YGR143W Protein involved in sphingolipid biosynthesis genetic 1 1 1 Synthetic Rescue
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth genetic 1 1 1 Synthetic Rescue
SLX4 YLR135W Endonuclease involved in processing DNA genetic 1 1 1 Synthetic Rescue
SLY41 YOR307C Protein involved in ER-to-Golgi transport genetic 1 1 1 Synthetic Rescue
SNA2 YDR525W-A Protein of unknown function genetic 1 1 1 Synthetic Rescue
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Rescue
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Synthetic Rescue
SNO1 YMR095C Protein of unconfirmed function genetic 1 1 1 Synthetic Rescue
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Synthetic Rescue
SNX3 YOR357C Sorting nexin for late-Golgi enzymes genetic 1 1 1 Synthetic Rescue
SOL1 YNR034W Protein with a possible role in tRNA export genetic 1 1 1 Synthetic Rescue
SOP4 YJL192C ER-membrane protein genetic 1 1 1 Synthetic Rescue
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Synthetic Rescue
SPG4 YMR107W Protein required for high temperature survival during stationary phase genetic 1 1 1 Synthetic Rescue
SPO22 YIL073C Meiosis-specific protein essential for chromosome synapsis genetic 1 1 1 Synthetic Rescue
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Synthetic Rescue
SRT1 YMR101C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Synthetic Rescue
SRX1 YKL086W Sulfiredoxin genetic 1 1 1 Synthetic Rescue
SSA2 YLL024C HSP70 family ATP-binding protein genetic 1 1 1 Synthetic Rescue
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Synthetic Rescue
STD1 YOR047C Protein involved in control of glucose-regulated gene expression genetic 1 1 1 Synthetic Rescue
STF2 YGR008C Protein involved in resistance to desiccation stress genetic 1 1 1 Synthetic Rescue
STP4 YDL048C Protein containing a Kruppel-type zinc-finger domain genetic 1 1 1 Synthetic Rescue
SUC2 YIL162W Invertase genetic 1 1 1 Synthetic Rescue
SVP26 YHR181W ER exit adaptor for Golgi mannosyltransferases genetic 1 1 1 Synthetic Rescue
SVS1 YPL163C Cell wall and vacuolar protein genetic 1 1 1 Synthetic Rescue
SWC7 YLR385C Protein of unknown function genetic 1 1 1 Synthetic Rescue
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Synthetic Rescue
SYP1 YCR030C Negative regulator of WASP-Arp23 complex genetic 1 1 1 Synthetic Rescue
TAD1 YGL243W tRNA-specific adenosine deaminase genetic 1 1 1 Synthetic Rescue
TAN1 YGL232W Putative tRNA acetyltransferase genetic 1 1 1 Synthetic Rescue
TCB1 YOR086C Lipid-binding ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Synthetic Rescue
TDH2 YJR009C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 genetic 1 1 1 Synthetic Rescue
TES1 YJR019C Peroxisomal acyl-CoA thioesterase genetic 1 1 1 Synthetic Rescue
TFS1 YLR178C Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p) genetic 1 1 1 Synthetic Rescue
TGL1 YKL140W Steryl ester hydrolase genetic 1 1 1 Synthetic Rescue
TIM13 YGR181W Mitochondrial intermembrane space protein genetic 1 1 1 Synthetic Rescue
TIR2 YOR010C Putative cell wall mannoprotein genetic 1 1 1 Synthetic Rescue
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation genetic 1 1 1 Synthetic Rescue
TOP3 YLR234W DNA Topoisomerase III genetic 1 1 1 Synthetic Rescue
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Synthetic Rescue
TRM10 YOL093W tRNA methyltransferase genetic 1 1 1 Synthetic Rescue
TRM12 YML005W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Synthetic Rescue
TRP4 YDR354W Anthranilate phosphoribosyl transferase genetic 1 1 1 Synthetic Rescue
TRS33 YOR115C Core component of TRAPP complexes I, II and IV genetic 1 1 1 Synthetic Rescue
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif genetic 1 1 1 Synthetic Rescue
UBC5 YDR059C Ubiquitin-conjugating enzyme genetic 1 1 1 Synthetic Rescue
UBP11 YKR098C Ubiquitin-specific protease genetic 1 1 1 Synthetic Rescue
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 1 1 1 Synthetic Rescue
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Synthetic Rescue
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme genetic 1 1 1 Synthetic Rescue
VCX1 YDL128W Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity genetic 1 1 1 Synthetic Rescue
VMA11 YPL234C Vacuolar ATPase V0 domain subunit c' genetic 1 1 1 Synthetic Rescue
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Synthetic Rescue
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Synthetic Rescue
VTH1 YIL173W Putative membrane glycoprotein genetic 1 1 1 Synthetic Rescue
WAR1 YML076C Homodimeric Zn2Cys6 zinc finger transcription factor genetic 1 1 1 Synthetic Rescue
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway genetic 1 1 1 Synthetic Rescue
YAT1 YAR035W Outer mitochondrial carnitine acetyltransferase genetic 1 1 1 Synthetic Rescue
YBP1 YBR216C Protein involved in cellular response to oxidative stress genetic 1 1 1 Synthetic Rescue
YBP2 YGL060W Central kinetochore associated protein genetic 1 1 1 Synthetic Rescue
YCP4 YCR004C Protein of unknown function genetic 1 1 1 Synthetic Rescue
YEH2 YLR020C Steryl ester hydrolase genetic 1 1 1 Synthetic Rescue
YHI9 YHR029C Protein of unknown function genetic 1 1 1 Synthetic Rescue
YHM2 YMR241W Citrate and oxoglutarate carrier protein genetic 1 1 1 Synthetic Rescue
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Synthetic Rescue
YNK1 YKL067W Nucleoside diphosphate kinase genetic 1 1 1 Synthetic Rescue
YOS9 YDR057W ER quality-control lectin genetic 1 1 1 Synthetic Rescue
YPK2 YMR104C AGC-type S/T protein kinase genetic 1 1 1 Synthetic Rescue
YPT35 YHR105W Endosomal protein of unknown function genetic 1 1 1 Synthetic Rescue
YPT52 YKR014C Endosomal Rab family GTPase genetic 1 1 1 Synthetic Rescue
YSC83 YHR017W Non-essential mitochondrial protein of unknown function genetic 1 1 1 Synthetic Rescue
YUR1 YJL139C Mannosyltransferase involved in protein N-glycosylation genetic 1 1 1 Synthetic Rescue
ZEO1 YOL109W Peripheral membrane protein of the plasma membrane genetic 1 1 1 Synthetic Rescue
PAU13 YHL046C Protein of unknown function genetic 1 1 1 Synthetic Rescue
POM33 YLL023C Transmembrane nucleoporin genetic 1 1 1 Synthetic Rescue
RGI1 YER067W Protein involved in energy metabolism under respiratory conditions genetic 1 1 1 Synthetic Rescue
RKM2 YDR198C Ribosomal protein lysine methyltransferase genetic 1 1 1 Synthetic Rescue
RRT13 YER066W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
RTC2 YBR147W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Synthetic Rescue
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p genetic 1 1 1 Synthetic Rescue
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling genetic 1 1 1 Synthetic Rescue
SAF1 YBR280C F-Box protein involved in proteasome-dependent degradation of Aah1p genetic 1 1 1 Synthetic Rescue
SAY1 YGR263C Sterol deacetylase genetic 1 1 1 Synthetic Rescue
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Synthetic Rescue
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
THI73 YLR004C Putative plasma membrane permease genetic 1 1 1 Synthetic Rescue
TRI1 YMR233W Non-essential sumoylated protein of unknown function genetic 1 1 1 Synthetic Rescue
TRM13 YOL125W 2'-O-methyltransferase genetic 1 1 1 Synthetic Rescue
TRM44 YPL030W tRNA(Ser) Um(44) 2'-O-methyltransferase genetic 1 1 1 Synthetic Rescue
VBA4 YDR119W Protein of unknown function genetic 1 1 1 Synthetic Rescue
VBA5 YKR105C Plasma membrane protein of the Major Facilitator Superfamily (MFS) genetic 1 1 1 Synthetic Rescue
VNX1 YNL321W Calcium/H+ antiporter localized to the endoplasmic reticulum membrane genetic 1 1 1 Synthetic Rescue
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 1 1 1 Synthetic Rescue
YPK3 YBR028C AGC kinase genetic 1 1 1 Synthetic Rescue
YGL117W YGL117W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YMR244W YMR244W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YEL023C YEL023C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YFR035C YFR035C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YIL165C YIL165C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YNR021W YNR021W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Synthetic Rescue
YCR023C YCR023C Vacuolar membrane protein of unknown function genetic 1 1 1 Synthetic Rescue
YLR287C YLR287C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YHL042W YHL042W Endoplasmic reticulum protein genetic 1 1 1 Synthetic Rescue
YIL024C YIL024C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YMR196W YMR196W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YDR222W YDR222W Protein of unknown function genetic 1 1 1 Synthetic Rescue
YPL108W YPL108W Cytoplasmic protein of unknown function genetic 1 1 1 Synthetic Rescue
YML020W YML020W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YOR012W YOR012W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YPL257W YPL257W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YCR102C YCR102C Putative quinone oxidoreductase genetic 1 1 1 Synthetic Rescue
YGL262W YGL262W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YLR152C YLR152C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YNL058C YNL058C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YMR206W YMR206W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YPL264C YPL264C Endoplasmic reticulum protein of unknown function genetic 1 1 1 Synthetic Rescue
YER079W YER079W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YKL075C YKL075C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YLR012C YLR012C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YNL092W YNL092W S-adenosylmethionine-dependent protein methyltransferase genetic 1 1 1 Synthetic Rescue
YHR022C YHR022C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
SDD2 YMR074C Protein with homology to human PDCD5 genetic 1 1 1 Synthetic Rescue
PDP3 YLR455W Component of the NuA3b histone acetyltransferase complex genetic 1 1 1 Synthetic Rescue
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YBL044W YBL044W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YJL107C YJL107C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YPR096C YPR096C Protein of unknown function genetic 1 1 1 Synthetic Rescue
YAR023C YAR023C Putative integral membrane protein genetic 1 1 1 Synthetic Rescue
YDR541C YDR541C Aldehyde reductase genetic 1 1 1 Synthetic Rescue
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Synthetic Rescue
YDL086W YDL086W Putative carboxymethylenebutenolidase genetic 1 1 1 Synthetic Rescue
PUL4 YNR063W Putative zinc-cluster transcription factor genetic 1 1 1 Synthetic Rescue
SEG1 YMR086W Component of eisosome required for proper eisosome assembly genetic 1 1 1 Synthetic Rescue
YNL034W YNL034W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YNL035C YNL035C Nuclear protein of unknown function genetic 1 1 1 Synthetic Rescue
YPR027C YPR027C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YNL320W YNL320W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YDL012C YDL012C Tail-anchored plasma membrane protein with a conserved CYSTM module genetic 1 1 1 Synthetic Rescue
YLR036C YLR036C Putative protein predicted to have transmembrane domains genetic 1 1 1 Synthetic Rescue
TCD2 YKL027W tRNA threonylcarbamoyladenosine dehydratase genetic 1 1 1 Synthetic Rescue
SDD3 YOL098C Putative metalloprotease genetic 1 1 1 Synthetic Rescue
YHL017W YHL017W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YOL024W YOL024W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Synthetic Rescue
YOR342C YOR342C Protein of unknown function genetic 1 1 1 Synthetic Rescue
YDR124W YDR124W Mitochondrial protein of unknown function genetic 1 1 1 Synthetic Rescue
YCR007C YCR007C Putative integral membrane protein genetic 1 1 1 Synthetic Rescue
YFR018C YFR018C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
RCI37 YIL077C Protein that associates with the large mitoribosomal subunit genetic 1 1 1 Synthetic Rescue
YMR027W YMR027W A metal-dependent phosphatase, part of the DUF89 protein family genetic 1 1 1 Synthetic Rescue
YNR014W YNR014W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YML100W-A YML100W-A Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YDL186W YDL186W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YPR089W YPR089W Protein of unknown function genetic 1 1 1 Synthetic Rescue
YOL013W-A YOL013W-A Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YNL108C YNL108C Protein phosphatase genetic 1 1 1 Synthetic Rescue
OSH3 YHR073W Member of an oxysterol-binding protein family genetic 1 1 1 Synthetic Rescue
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Synthetic Rescue
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Synthetic Rescue
SND3 YBR106W Involved in SRP-independent protein targeting to the ER genetic 1 1 1 Synthetic Rescue
PIC2 YER053C Mitochondrial copper and phosphate carrier genetic 1 1 1 Synthetic Rescue
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder genetic 1 1 1 Synthetic Rescue
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 1 1 1 Synthetic Rescue
PRM5 YIL117C Pheromone-regulated protein, predicted to have 1 transmembrane segment genetic 1 1 1 Synthetic Rescue
QCR7 YDR529C Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Synthetic Rescue
SUT1 YGL162W Zn(II)2Cys6 family transcription factor genetic 1 1 1 Synthetic Rescue
QDR1 YIL120W Multidrug transporter of the major facilitator superfamily genetic 1 1 1 Synthetic Rescue
SVF1 YDR346C Protein with a potential role in cell survival pathways genetic 1 1 1 Synthetic Rescue
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Synthetic Rescue
TDA9 YML081W Transcription factor that regulates acetate production genetic 1 1 1 Synthetic Rescue
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Synthetic Rescue
TMN3 YER113C Protein with a role in cellular adhesion and filamentous growth genetic 1 1 1 Synthetic Rescue
RKM1 YPL208W SET-domain lysine-N-methyltransferase genetic 1 1 1 Synthetic Rescue
TMT1 YER175C Trans-aconitate methyltransferase genetic 1 1 1 Synthetic Rescue
ZNF1 YFL052W Zinc cluster transcription factor that regulates respiratory growth genetic 1 1 1 Synthetic Rescue
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Synthetic Rescue
RPL12A YEL054C Ribosomal 60S subunit protein L12A genetic 1 1 1 Synthetic Rescue
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 1 1 1 Synthetic Rescue
RPL16B YNL069C Ribosomal 60S subunit protein L16B genetic 1 1 1 Synthetic Rescue
VTC1 YER072W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Synthetic Rescue
RPL2B YIL018W Ribosomal 60S subunit protein L2B genetic 1 1 1 Synthetic Rescue
RPS1B YML063W Ribosomal protein of the small (40S) subunit genetic 1 1 1 Synthetic Rescue
RSN1 YMR266W Membrane protein of unknown function genetic 1 1 1 Synthetic Rescue
SAG1 YJR004C Alpha-agglutinin of alpha-cells genetic 1 1 1 Synthetic Rescue
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex genetic 1 1 1 Synthetic Rescue
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Synthetic Rescue
SPO71 YDR104C Meiosis-specific protein required for prospore membrane morphogenesis genetic 1 1 1 Synthetic Rescue
STP3 YLR375W Zinc-finger protein of unknown function genetic 1 1 1 Synthetic Rescue
VTC4 YJL012C Vacuolar membrane polyphosphate polymerase genetic 1 1 1 Synthetic Rescue
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Synthetic Lethality
YAT2 YER024W Carnitine acetyltransferase genetic 1 1 1 Synthetic Rescue
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Synthetic Rescue
YML082W YML082W Putative protein predicted to have carbon-sulfur lyase activity genetic 1 1 1 Synthetic Rescue
YML083C YML083C Protein of unknown function genetic 1 1 1 Synthetic Rescue
YML079W YML079W Non-essential protein of unknown function genetic 1 1 1 Synthetic Rescue
SDH7 YDR511W Mitochondrial protein involved in assembly of succinate dehydrogenase genetic 1 1 1 Synthetic Rescue
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Growth Defect
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Synthetic Lethality
PDR10 YOR328W ATP-binding cassette (ABC) transporter genetic 1 1 1 Synthetic Rescue
PDR3 YBL005W Transcriptional activator of the pleiotropic drug resistance network genetic 1 1 1 Synthetic Rescue
PDR5 YOR153W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Synthetic Rescue
PDX1 YGR193C E3-binding protein of the mitochondrial pyruvate dehydrogenase complex genetic 1 1 1 Synthetic Rescue
YJL028W YJL028W Protein of unknown function genetic 1 1 1 Synthetic Rescue
YGL242C YGL242C Protein of unknown function genetic 1 1 1 Synthetic Rescue
YOR008C-A YOR008C-A Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
TML25 YLR118C Acyl-protein thioesterase responsible for depalmitoylation of Gpa1p genetic 1 1 1 Synthetic Rescue
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 1 1 1 Synthetic Rescue
NPY1 YGL067W NADH diphosphatase (pyrophosphatase) genetic 1 1 1 Synthetic Rescue
NRK1 YNL129W Nicotinamide riboside kinase genetic 1 1 1 Synthetic Rescue
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Synthetic Rescue
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Synthetic Rescue
NTH2 YBR001C Putative neutral trehalase, required for thermotolerance genetic 1 1 1 Synthetic Rescue
OAC1 YKL120W Mitochondrial inner membrane transporter genetic 1 1 1 Synthetic Rescue
OPT1 YJL212C Proton-coupled oligopeptide transporter of the plasma membrane genetic 1 1 1 Synthetic Rescue
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Synthetic Rescue
PAI3 YMR174C Cytoplasmic proteinase A (Pep4p) inhibitor genetic 1 1 1 Synthetic Rescue
PAU24 YBR301W Cell wall mannoprotein genetic 1 1 1 Synthetic Rescue
PAU5 YFL020C Member of the seripauperin multigene family genetic 1 1 1 Synthetic Rescue
PAU7 YAR020C Member of the seripauperin multigene family genetic 1 1 1 Synthetic Rescue
PCI8 YIL071C Possible shared subunit of Cop9 signalosome (CSN) and eIF3 genetic 1 1 1 Synthetic Rescue
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Synthetic Growth Defect
PLC1 YPL268W Phospholipase C genetic 1 1 1 Synthetic Growth Defect
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Synthetic Growth Defect
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p genetic 1 1 1 Synthetic Growth Defect
RPL42A YNL162W Ribosomal 60S subunit protein L42A genetic 1 1 1 Synthetic Growth Defect
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Synthetic Growth Defect
SNX41 YDR425W Sorting nexin genetic 1 1 1 Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Synthetic Growth Defect
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Synthetic Growth Defect
SYS1 YJL004C Integral membrane protein of the Golgi genetic 1 1 1 Synthetic Growth Defect
VAC14 YLR386W Enzyme regulator genetic 1 1 1 Synthetic Growth Defect
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Synthetic Growth Defect
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Synthetic Growth Defect
YDR415C YDR415C Putative aminopeptidase genetic 1 1 1 Synthetic Growth Defect
THI74 YDR438W Mitochondrial transporter repressible by thiamine genetic 1 1 1 Synthetic Growth Defect
OXR1 YPL196W Protein involved in regulation of vacuolar V-ATPase genetic 1 1 1 Synthetic Growth Defect
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Synthetic Growth Defect
RRT6 YGL146C Integral membrane protein, member of the p24 family genetic 1 1 1 Synthetic Growth Defect
PFA5 YDR459C Palmitoyltransferase with autoacylation activity genetic 1 1 1 Synthetic Growth Defect
NRG1 YDR043C Transcriptional repressor genetic 1 1 1 Synthetic Growth Defect
NTC20 YBR188C Member of the NineTeen Complex (NTC) genetic 1 1 1 Synthetic Growth Defect
NUC1 YJL208C Major mitochondrial nuclease genetic 1 1 1 Synthetic Growth Defect
OCH1 YGL038C Mannosyltransferase of the cis-Golgi apparatus genetic 1 1 1 Synthetic Growth Defect
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Synthetic Growth Defect
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Synthetic Growth Defect
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes genetic 1 1 1 Synthetic Growth Defect
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Synthetic Growth Defect
PEA2 YER149C Coiled-coil 12S polarisome subunit genetic 1 1 1 Synthetic Growth Defect
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Synthetic Growth Defect
PER1 YCR044C Protein of the endoplasmic reticulum genetic 1 1 1 Synthetic Growth Defect
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein genetic 1 1 1 Synthetic Growth Defect
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Synthetic Growth Defect
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane genetic 1 1 1 Synthetic Growth Defect
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 1 1 1 Synthetic Growth Defect
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Synthetic Growth Defect
RAD26 YJR035W Protein involved in transcription-coupled nucleotide excision repair genetic 1 1 1 Synthetic Growth Defect
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Synthetic Growth Defect
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Synthetic Growth Defect
REC102 YLR329W Protein involved in early stages of meiotic recombination genetic 1 1 1 Synthetic Growth Defect
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Synthetic Growth Defect
RPA12 YJR063W RNA polymerase I subunit A12.2 genetic 1 1 1 Synthetic Growth Defect
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Synthetic Growth Defect
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase genetic 1 1 1 Synthetic Growth Defect
RPL19B YBL027W Ribosomal 60S subunit protein L19B genetic 1 1 1 Synthetic Growth Defect
RPL21A YBR191W Ribosomal 60S subunit protein L21A genetic 1 1 1 Synthetic Growth Defect
RPL34B YIL052C Ribosomal 60S subunit protein L34B genetic 1 1 1 Synthetic Growth Defect
RPL35B YDL136W Ribosomal 60S subunit protein L35B genetic 1 1 1 Synthetic Growth Defect
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein genetic 1 1 1 Synthetic Growth Defect
RPL41A YDL184C Ribosomal 60S subunit protein L41A genetic 1 1 1 Synthetic Growth Defect
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Synthetic Growth Defect
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Synthetic Growth Defect
RTN1 YDR233C Reticulon protein genetic 1 1 1 Synthetic Growth Defect
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Synthetic Growth Defect
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Synthetic Growth Defect
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Synthetic Growth Defect
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Synthetic Growth Defect
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Synthetic Growth Defect
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Synthetic Growth Defect
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Synthetic Growth Defect
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Synthetic Growth Defect
SOL3 YHR163W 6-phosphogluconolactonase genetic 1 1 1 Synthetic Growth Defect
SSE2 YBR169C Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family genetic 1 1 1 Synthetic Growth Defect
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 1 1 1 Synthetic Growth Defect
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 1 1 1 Synthetic Growth Defect
TCB2 YNL087W ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Synthetic Growth Defect
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Synthetic Growth Defect
TIF2 YJL138C Translation initiation factor eIF4A genetic 1 1 1 Synthetic Growth Defect
TIR1 YER011W Cell wall mannoprotein genetic 1 1 1 Synthetic Growth Defect
TSA2 YDR453C Stress inducible cytoplasmic thioredoxin peroxidase genetic 1 1 1 Synthetic Growth Defect
UBC13 YDR092W E2 ubiquitin-conjugating enzyme genetic 1 1 1 Synthetic Growth Defect
UBI4 YLL039C Ubiquitin genetic 1 1 1 Synthetic Growth Defect
UBP14 YBR058C Ubiquitin-specific protease genetic 1 1 1 Synthetic Growth Defect
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Synthetic Growth Defect
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes genetic 1 1 1 Synthetic Growth Defect
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Synthetic Growth Defect
URA7 YBL039C Major CTP synthase isozyme (see also URA8) genetic 1 1 1 Synthetic Growth Defect
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Synthetic Growth Defect
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Synthetic Growth Defect
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Synthetic Growth Defect
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Synthetic Growth Defect
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 1 1 1 Synthetic Growth Defect
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Synthetic Growth Defect
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Synthetic Growth Defect
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Synthetic Growth Defect
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Synthetic Growth Defect
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Synthetic Growth Defect
VPS75 YNL246W NAP family histone chaperone genetic 1 1 1 Synthetic Growth Defect
VTA1 YLR181C Multivesicular body (MVB) protein genetic 1 1 1 Synthetic Growth Defect
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 1 1 1 Synthetic Growth Defect
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Synthetic Growth Defect
YJU3 YKL094W Monoglyceride lipase (MGL) that hydrolyzes fatty acid ethyl esters genetic 1 1 1 Synthetic Growth Defect
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Synthetic Growth Defect
YPT31 YER031C Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
YPT7 YML001W Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
YRM1 YOR172W Zinc finger transcription factor involved in multidrug resistance genetic 1 1 1 Synthetic Growth Defect
YSA1 YBR111C Nudix hydrolase family member with ADP-ribose pyrophosphatase activity genetic 1 1 1 Synthetic Growth Defect
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Synthetic Growth Defect
YPK9 YOR291W Vacuolar protein with a possible role in sequestering heavy metals genetic 1 1 1 Synthetic Growth Defect
YIL092W YIL092W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YOR296W YOR296W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p genetic 1 1 1 Synthetic Growth Defect
RAD34 YDR314C Protein involved in nucleotide excision repair (NER) genetic 1 1 1 Synthetic Growth Defect
YDR248C YDR248C Putative gluconokinase genetic 1 1 1 Synthetic Growth Defect
YPR097W YPR097W Protein that contains a PX domain and binds phosphoinositides genetic 1 1 1 Synthetic Growth Defect
YHR033W YHR033W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Synthetic Growth Defect
YDR338C YDR338C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YNR071C YNR071C Putative aldose 1-epimerase genetic 1 1 1 Synthetic Growth Defect
RKM3 YBR030W Ribosomal lysine methyltransferase genetic 1 1 1 Synthetic Growth Defect
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Synthetic Growth Defect
HPR1 YDR138W Subunit of THO/TREX complexes genetic 1 1 1 Phenotypic Suppression
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Synthetic Growth Defect
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Synthetic Rescue
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 1 1 1 Affinity Capture-Western
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Synthetic Rescue
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 genetic 1 1 1 Synthetic Growth Defect
ATG14 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I genetic 1 1 1 Synthetic Rescue
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Synthetic Growth Defect
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Synthetic Growth Defect
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 1 1 1 Synthetic Rescue
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly genetic 1 1 1 Synthetic Growth Defect
AIM21 YIR003W Subunit of a complex that associates with actin filaments genetic 1 1 1 Synthetic Rescue
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Synthetic Rescue
BOI2 YER114C Protein involved in polar growth genetic 1 1 1 Synthetic Rescue
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Synthetic Growth Defect
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Synthetic Growth Defect
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Synthetic Rescue
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Synthetic Growth Defect
ERP1 YAR002C-A Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Synthetic Rescue
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Synthetic Growth Defect
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Synthetic Rescue
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator genetic 1 1 1 Synthetic Growth Defect
AEP2 YMR282C Mitochondrial protein genetic 1 1 1 Synthetic Rescue
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
HSM3 YBR272C Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 1 1 1 Synthetic Rescue
HST1 YOL068C NAD(+)-dependent histone deacetylase genetic 1 1 1 Synthetic Rescue
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
IOC3 YFR013W Subunit of the Isw1a complex genetic 1 1 1 Synthetic Rescue
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Synthetic Rescue
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Synthetic Rescue
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Synthetic Growth Defect
LSM4 YER112W Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-Western
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Synthetic Growth Defect
LUC7 YDL087C Essential protein associated with the U1 snRNP complex physical 1 1 1 Affinity Capture-Western
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) genetic 1 1 1 Synthetic Rescue
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Rescue
ADA2 YDR448W Transcription coactivator genetic 1 1 1 Synthetic Growth Defect
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
MHR1 YDR296W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Rescue
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Synthetic Growth Defect
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Negative Genetic
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 1 1 1 Synthetic Rescue
MLC2 YPR188C Regulatory light chain for the type II myosin Myo1p genetic 1 1 1 Synthetic Rescue
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins genetic 1 1 1 Positive Genetic
LYS12 YIL094C Homo-isocitrate dehydrogenase genetic 1 1 1 Synthetic Rescue
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Synthetic Growth Defect
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit physical 1 1 1 Affinity Capture-Western
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity genetic 1 1 1 Synthetic Rescue
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Synthetic Rescue
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Lethality
LEA1 YPL213W Component of U2 snRNP complex physical 1 1 1 Co-localization
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) physical 1 1 1 Affinity Capture-MS
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome genetic 1 1 1 Positive Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Synthetic Rescue
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Two-hybrid
MLH2 YLR035C Protein involved in mismatch repair and meiotic recombination genetic 1 1 1 Synthetic Rescue
CSI1 YMR025W Subunit of the Cop9 signalosome genetic 1 1 1 Synthetic Rescue
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Synthetic Growth Defect
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Synthetic Growth Defect
HRK1 YOR267C Protein kinase physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-Western
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Negative Genetic
BUR2 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase physical 1 1 1 Affinity Capture-MS
CRN1 YLR429W Coronin genetic 1 1 1 Synthetic Growth Defect
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Synthetic Lethality
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Synthetic Growth Defect
GTO3 YMR251W Omega class glutathione transferase genetic 1 1 1 Synthetic Growth Defect
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Synthetic Growth Defect
FLC2 YAL053W Putative calcium channel involved in calcium release under hypotonic genetic 1 1 1 Synthetic Growth Defect
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p genetic 1 1 1 Synthetic Growth Defect
CYM1 YDR430C Lysine-specific metalloprotease of the pitrilysin family genetic 1 1 1 Synthetic Growth Defect
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Synthetic Growth Defect
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton genetic 1 1 1 Synthetic Growth Defect
CSR2 YPR030W Nuclear ubiquitin protein ligase binding protein genetic 1 1 1 Synthetic Growth Defect
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Synthetic Rescue
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 1 1 1 Affinity Capture-MS
APP1 YNL094W Phosphatidate phosphatase, converts phosphatidate to diacylglycerol genetic 1 1 1 Synthetic Rescue
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
HTB1 YDR224C Histone H2B physical 1 1 1 Affinity Capture-MS
HTB1 YDR224C Histone H2B genetic 1 1 1 Synthetic Growth Defect
CMP2 YML057W Calcineurin A genetic 1 1 1 Synthetic Rescue
GDE1 YPL110C Glycerophosphocholine (GroPCho) phosphodiesterase genetic 1 1 1 Synthetic Growth Defect
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
KOG1 YHR186C Subunit of TORC1 physical 1 1 1 Affinity Capture-MS
BUD13 YGL174W Subunit of the RES complex genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Synthetic Growth Defect
LCP5 YER127W Essential protein involved in maturation of 18S rRNA genetic 1 1 1 Positive Genetic
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) genetic 1 1 1 Synthetic Growth Defect
CMK1 YFR014C Calmodulin-dependent protein kinase genetic 1 1 1 Synthetic Rescue
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Synthetic Rescue
AMF1 YOR378W Low affinity NH4+ transporter genetic 1 1 1 Synthetic Rescue
GPD2 YOL059W NAD-dependent glycerol 3-phosphate dehydrogenase genetic 1 1 1 Synthetic Rescue
MDM30 YLR368W F-box component of an SCF ubiquitin protein ligase complex genetic 1 1 1 Synthetic Rescue
FAR1 YJL157C CDK inhibitor and nuclear anchor genetic 1 1 1 Synthetic Rescue
ATG42 YBR139W Vacuolar serine-type carboxypeptidase genetic 1 1 1 Synthetic Rescue
CYC8 YBR112C General transcriptional co-repressor physical 1 1 1 Affinity Capture-MS
DBF20 YPR111W Ser/Thr kinase involved in late nuclear division genetic 1 1 1 Synthetic Rescue
MAE1 YKL029C Mitochondrial malic enzyme genetic 1 1 1 Synthetic Rescue
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Synthetic Growth Defect
FUM1 YPL262W Fumarase genetic 1 1 1 Synthetic Growth Defect
LAF1 YMR102C Sterol-binding beta-propeller protein genetic 1 1 1 Synthetic Rescue
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
GPP2 YER062C DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis genetic 1 1 1 Synthetic Rescue
GID8 YMR135C Subunit of GID Complex, binds strongly to central component Vid30p genetic 1 1 1 Synthetic Rescue
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein genetic 1 1 1 Synthetic Rescue
ART10 YLR392C Protein of unknown function that contains 2 PY motifs genetic 1 1 1 Synthetic Rescue
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase genetic 1 1 1 Synthetic Growth Defect
LTP1 YPR073C Protein phosphotyrosine phosphatase of unknown cellular role genetic 1 1 1 Synthetic Rescue
DSS4 YPR017C Guanine nucleotide dissociation stimulator for Sec4p genetic 1 1 1 Synthetic Rescue
GRX1 YCL035C Glutathione-dependent disulfide oxidoreductase genetic 1 1 1 Synthetic Rescue
ISN1 YOR155C Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase genetic 1 1 1 Synthetic Rescue
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Synthetic Lethality
GAL7 YBR018C Galactose-1-phosphate uridyl transferase genetic 1 1 1 Synthetic Rescue
GPG1 YGL121C Proposed gamma subunit of the heterotrimeric G protein genetic 1 1 1 Synthetic Rescue
MAG2 YLR427W Cytoplasmic protein of unknown function physical 1 1 1 Affinity Capture-MS
GIS4 YML006C CAAX box containing protein of unknown function genetic 1 1 1 Synthetic Rescue
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome physical 1 1 1 Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Synthetic Rescue
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Synthetic Growth Defect
EMI2 YDR516C Hexokinase expressed during growth with low glucose levels genetic 1 1 1 Synthetic Rescue
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 1 1 1 Synthetic Rescue
HHT1 YBR010W Histone H3 genetic 1 1 1 Synthetic Rescue
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Synthetic Rescue
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Synthetic Growth Defect
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex genetic 1 1 1 Synthetic Rescue
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Growth Defect
MKK2 YPL140C MAPKK involved in the protein kinase C signaling pathway genetic 1 1 1 Synthetic Rescue
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Synthetic Rescue
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase genetic 1 1 1 Synthetic Growth Defect
ATG20 YDL113C Sorting nexin family member genetic 1 1 1 Synthetic Rescue
FPK1 YNR047W Ser/Thr protein kinase genetic 1 1 1 Synthetic Rescue
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Synthetic Growth Defect
MIH1 YMR036C Protein tyrosine phosphatase genetic 1 1 1 Synthetic Growth Defect
BUD9 YGR041W Protein involved in bud-site selection genetic 1 1 1 Synthetic Rescue
GAL3 YDR009W Transcriptional regulator genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
GSY1 YFR015C Glycogen synthase genetic 1 1 1 Synthetic Rescue
MDH2 YOL126C Cytoplasmic malate dehydrogenase genetic 1 1 1 Synthetic Rescue
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Synthetic Rescue
HXT5 YHR096C Hexose transporter with moderate affinity for glucose genetic 1 1 1 Synthetic Rescue
ELC1 YPL046C Elongin C, conserved among eukaryotes genetic 1 1 1 Synthetic Rescue
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Synthetic Growth Defect
LAA1 YJL207C AP-1 accessory protein genetic 1 1 1 Synthetic Rescue
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Synthetic Growth Defect
CTR1 YPR124W High-affinity copper transporter of plasma membrane genetic 1 1 1 Synthetic Growth Defect
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E physical 1 1 1 Affinity Capture-MS
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Synthetic Growth Defect
CPR3 YML078W Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Synthetic Rescue
LOS1 YKL205W Nuclear pore protein genetic 1 1 1 Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Negative Genetic
MSG5 YNL053W Dual-specificity protein phosphatase genetic 1 1 1 Synthetic Rescue
MIC19 YFR011C Component of the MICOS complex genetic 1 1 1 Synthetic Rescue
GBP2 YCL011C Poly(A+) RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
CSC1 YLR241W Calcium permeable gated cation channel genetic 1 1 1 Synthetic Growth Defect
MDH3 YDL078C Peroxisomal malate dehydrogenase genetic 1 1 1 Synthetic Rescue
GCY1 YOR120W Glycerol dehydrogenase genetic 1 1 1 Synthetic Rescue
MRX1 YER077C Protein that associates with mitochondrial ribosome genetic 1 1 1 Synthetic Rescue
CHZ1 YER030W Histone chaperone for Htz1p/H2A-H2B dimer genetic 1 1 1 Synthetic Rescue
EXG1 YLR300W Major exo-1,3-beta-glucanase of the cell wall genetic 1 1 1 Synthetic Rescue
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
APL4 YPR029C Gamma-adaptin genetic 1 1 1 Synthetic Rescue
ASI3 YNL008C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Synthetic Rescue
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Synthetic Growth Defect
ADH5 YBR145W Alcohol dehydrogenase isoenzyme V genetic 1 1 1 Synthetic Rescue
CTK3 YML112W Gamma subunit of C-terminal domain kinase I physical 1 1 1 Affinity Capture-MS
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Synthetic Growth Defect
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Synthetic Growth Defect
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
FZF1 YGL254W Transcription factor involved in sulfite metabolism genetic 1 1 1 Synthetic Rescue
CSM2 YIL132C Subunit of the Shu complex (aka PCSS complex) genetic 1 1 1 Synthetic Growth Defect
BIT2 YBR270C Subunit of TORC2 membrane-associated complex genetic 1 1 1 Synthetic Rescue
LAC1 YKL008C Ceramide synthase component genetic 1 1 1 Synthetic Rescue
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase genetic 1 1 1 Synthetic Growth Defect
CIT2 YCR005C Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle genetic 1 1 1 Synthetic Rescue
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Synthetic Lethality
ECM19 YLR390W Protein of unknown function genetic 1 1 1 Synthetic Rescue
ENT3 YJR125C Protein containing an N-terminal epsin-like domain physical 1 1 1 Reconstituted Complex
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 1 1 1 Synthetic Growth Defect
GIP1 YBR045C Meiosis-specific regulatory subunit of the Glc7p protein phosphatase genetic 1 1 1 Synthetic Rescue
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Synthetic Growth Defect
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Synthetic Rescue
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Synthetic Growth Defect
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Synthetic Growth Defect
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex genetic 1 1 1 Synthetic Rescue
HUA2 YOR284W Cytoplasmic protein of unknown function genetic 1 1 1 Synthetic Rescue
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 1 1 1 Synthetic Growth Defect
IKS1 YJL057C Protein kinase of unknown cellular role genetic 1 1 1 Synthetic Rescue
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation genetic 1 1 1 Synthetic Rescue
GNP1 YDR508C Broad specificity amino acid permease genetic 1 1 1 Synthetic Growth Defect
ACF4 YJR083C Protein of unknown function genetic 1 1 1 Synthetic Rescue
JSN1 YJR091C Member of the Puf family of RNA-binding proteins genetic 1 1 1 Synthetic Rescue
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site genetic 1 1 1 Synthetic Growth Defect
ECI1 YLR284C Peroxisomal delta3,delta2-enoyl-CoA isomerase genetic 1 1 1 Synthetic Rescue
AIM18 YHR198C Protein of unknown function genetic 1 1 1 Synthetic Rescue
DAS2 YDR020C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
MST27 YGL051W Putative integral membrane protein, involved in vesicle formation genetic 1 1 1 Synthetic Rescue
NMA2 YGR010W Nicotinic acid mononucleotide adenylyltransferase genetic 1 1 1 Synthetic Growth Defect
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Synthetic Rescue
MET14 YKL001C Adenylylsulfate kinase genetic 1 1 1 Synthetic Growth Defect
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
APC9 YLR102C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Synthetic Rescue
CDC26 YFR036W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Synthetic Growth Defect
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
MRP2 YPR166C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Growth Defect
HOT1 YMR172W Transcription factor for glycerol biosynthetic genes physical 1 1 1 Affinity Capture-MS
AMD1 YML035C AMP deaminase genetic 1 1 1 Synthetic Rescue
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Synthetic Growth Defect
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Synthetic Growth Defect
HPC2 YBR215W Subunit of the HIR complex genetic 1 1 1 Synthetic Growth Defect
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
ALF1 YNL148C Alpha-tubulin folding protein genetic 1 1 1 Synthetic Growth Defect
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) physical 1 1 1 Affinity Capture-MS
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
IOC2 YLR095C Subunit of the Isw1b complex genetic 1 1 1 Synthetic Rescue
IOC4 YMR044W Member of a complex (Isw1b) with Isw1p and Ioc2p genetic 1 1 1 Synthetic Rescue
KAR9 YPL269W Spindle positioning factor genetic 1 1 1 Synthetic Rescue
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway genetic 1 1 1 Synthetic Rescue
ATS1 YAL020C Protein required for modification of wobble nucleosides in tRNA genetic 1 1 1 Synthetic Rescue
NIS1 YNL078W Protein involved in axial bud site selection genetic 1 1 1 Synthetic Growth Defect
DPH1 YIL103W Protein required for synthesis of diphthamide genetic 1 1 1 Synthetic Rescue
HRB1 YNL004W Poly(A+) RNA-binding protein physical 1 1 1 Affinity Capture-MS
HAP4 YKL109W Transcription factor genetic 1 1 1 Synthetic Rescue
BAG7 YOR134W Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Synthetic Rescue
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
GAL80 YML051W Transcriptional regulator involved in the repression of GAL genes genetic 1 1 1 Synthetic Growth Defect
EMC1 YCL045C Member of conserved endoplasmic reticulum membrane complex genetic 1 1 1 Synthetic Rescue
MSO1 YNR049C Lipid-interacting protein in SNARE complex assembly machinery genetic 1 1 1 Synthetic Rescue
EMC5 YIL027C Member of conserved ER transmembrane complex genetic 1 1 1 Synthetic Rescue
AFI1 YOR129C Arf3p polarization-specific docking factor genetic 1 1 1 Synthetic Rescue
DAL80 YKR034W Negative regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Synthetic Rescue
GSY2 YLR258W Glycogen synthase genetic 1 1 1 Synthetic Rescue
HCH1 YNL281W Heat shock protein regulator genetic 1 1 1 Synthetic Rescue
EMA17 YIL029C Protein involved in targeting mitochondrial membrane protein precursor genetic 1 1 1 Synthetic Rescue
ATC1 YDR184C Nuclear protein genetic 1 1 1 Synthetic Rescue
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Synthetic Growth Defect
MET31 YPL038W Zinc-finger DNA-binding transcription factor genetic 1 1 1 Synthetic Rescue
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 1 1 1 Synthetic Growth Defect
GFD2 YCL036W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p genetic 1 1 1 Synthetic Rescue
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Synthetic Rescue
DFG5 YMR238W Putative mannosidase genetic 1 1 1 Synthetic Rescue
ACF2 YLR144C Intracellular beta-1,3-endoglucanase genetic 1 1 1 Synthetic Growth Defect
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly genetic 1 1 1 Synthetic Rescue
MCA1 YOR197W Ca2+-dependent cysteine protease physical 1 1 1 Affinity Capture-MS
FUS1 YCL027W Membrane protein localized to the shmoo tip genetic 1 1 1 Synthetic Rescue
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Synthetic Rescue
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex physical 1 1 1 Protein-RNA
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 1 1 1 Synthetic Growth Defect
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin genetic 1 1 1 Synthetic Growth Defect
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway genetic 1 1 1 Synthetic Growth Defect
ENT5 YDR153C Protein containing an N-terminal epsin-like domain physical 1 1 1 Reconstituted Complex
ENT5 YDR153C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Synthetic Rescue
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Synthetic Growth Defect
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein genetic 1 1 1 Synthetic Growth Defect
ACM1 YPL267W Pseudosubstrate inhibitor of the APC/C genetic 1 1 1 Synthetic Rescue
CLB3 YDL155W B-type cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Growth Defect
COX19 YLL018C-A Protein required for cytochrome c oxidase assembly genetic 1 1 1 Synthetic Rescue
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
FOX2 YKR009C 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase genetic 1 1 1 Synthetic Growth Defect
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Synthetic Rescue
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Synthetic Growth Defect
MTD1 YKR080W NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase genetic 1 1 1 Synthetic Rescue
CCC1 YLR220W Vacuolar Fe2+/Mn2+ transporter genetic 1 1 1 Synthetic Rescue
ECM21 YBL101C Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p genetic 1 1 1 Synthetic Rescue
AUS1 YOR011W Plasma membrane sterol transporter of the ATP-binding cassette family physical 1 1 1 Protein-peptide
AUS1 YOR011W Plasma membrane sterol transporter of the ATP-binding cassette family genetic 1 1 1 Synthetic Rescue
EPO1 YMR124W Protein involved in septin-ER tethering genetic 1 1 1 Synthetic Rescue
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 1 1 1 Synthetic Rescue
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity genetic 1 1 1 Synthetic Growth Defect
CPS1 YJL172W Vacuolar carboxypeptidase S genetic 1 1 1 Synthetic Growth Defect
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Synthetic Growth Defect
EXG2 YDR261C Exo-1,3-beta-glucanase genetic 1 1 1 Synthetic Rescue
HLR1 YDR528W Protein involved in regulation of cell wall composition and integrity genetic 1 1 1 Synthetic Rescue
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine genetic 1 1 1 Synthetic Rescue
GEF1 YJR040W Voltage-gated chloride channel genetic 1 1 1 Synthetic Rescue
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription genetic 1 1 1 Synthetic Rescue
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
CIR1 YGR207C Mitochondrial protein that interacts with frataxin (Yfh1p) genetic 1 1 1 Synthetic Rescue
AIM45 YPR004C Putative ortholog of mammalian ETF-alpha genetic 1 1 1 Synthetic Rescue
MSC2 YDR205W Endoplasmic reticulum zinc transporter genetic 1 1 1 Synthetic Rescue
DAL5 YJR152W Allantoate permease genetic 1 1 1 Synthetic Rescue
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 1 1 1 Synthetic Rescue
DSF2 YBR007C Deletion suppressor of mpt5 mutation genetic 1 1 1 Synthetic Rescue
CUE1 YMR264W Ubiquitin-binding protein genetic 1 1 1 Synthetic Rescue
DIC1 YLR348C Mitochondrial dicarboxylate carrier genetic 1 1 1 Synthetic Rescue
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase genetic 1 1 1 Synthetic Rescue
BOL3 YAL046C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 1 1 1 Synthetic Rescue
FRE3 YOR381W Ferric reductase genetic 1 1 1 Synthetic Rescue
MCH1 YDL054C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Synthetic Rescue
COQ10 YOL008W Coenzyme Q (ubiquinone) binding protein genetic 1 1 1 Synthetic Rescue
LYS4 YDR234W Homoaconitase genetic 1 1 1 Synthetic Rescue
GID11 YLR149C Substrate receptor of the glucose-induced degradation-deficient (GID) genetic 1 1 1 Synthetic Rescue
AEP3 YPL005W Peripheral mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
COQ11 YLR290C Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes genetic 1 1 1 Synthetic Rescue
MET10 YFR030W Subunit alpha of assimilatory sulfite reductase genetic 1 1 1 Synthetic Rescue
BNA1 YJR025C 3-hydroxyanthranilic acid dioxygenase genetic 1 1 1 Synthetic Rescue
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy genetic 1 1 1 Synthetic Rescue
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Synthetic Rescue
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Synthetic Growth Defect
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis genetic 1 1 1 Synthetic Rescue
GUT1 YHL032C Glycerol kinase genetic 1 1 1 Synthetic Rescue
ADH7 YCR105W NADPH-dependent medium chain alcohol dehydrogenase genetic 1 1 1 Synthetic Rescue
MUK1 YPL070W Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Rescue
ANB1 YJR047C Translation elongation factor eIF-5A genetic 1 1 1 Synthetic Rescue
FMP46 YKR049C Putative redox protein containing a thioredoxin fold genetic 1 1 1 Synthetic Rescue
LOT6 YLR011W FMN-dependent NAD(P)H:quinone reductase genetic 1 1 1 Synthetic Rescue
MEF1 YLR069C Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
APS1 YLR170C Small subunit of the clathrin-associated adaptor complex AP-1 genetic 1 1 1 Synthetic Rescue
NCW2 YLR194C GPI-anchored protein involved in cell wall remodeling genetic 1 1 1 Synthetic Rescue
AIM26 YKL037W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ECM3 YOR092W Non-essential protein of unknown function genetic 1 1 1 Synthetic Rescue
ANY1 YMR010W Protein involved in phospholipid flippase function genetic 1 1 1 Synthetic Rescue
DIN7 YDR263C Mitochondrial nuclease functioning in DNA repair and replication genetic 1 1 1 Synthetic Rescue
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
MSB1 YOR188W Protein of unknown function genetic 1 1 1 Synthetic Rescue
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Synthetic Growth Defect
ATF2 YGR177C Alcohol acetyltransferase genetic 1 1 1 Synthetic Rescue
EGH1 YIR007W Steryl-beta-glucosidase with broad specificity for aglycones genetic 1 1 1 Synthetic Rescue
ATP25 YMR098C Protein that associates with mitochondrial ribosome genetic 1 1 1 Synthetic Rescue
MIL1 YFL034W Predicted lipase genetic 1 1 1 Synthetic Rescue
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Synthetic Rescue
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Synthetic Growth Defect
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 1 1 1 Synthetic Growth Defect
ABP140 YOR239W AdoMet-dependent tRNA methyltransferase and actin binding protein genetic 1 1 1 Synthetic Rescue
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
CTH1 YDR151C mRNA binding protein, member of the CCCH zinc finger family genetic 1 1 1 Synthetic Rescue
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen genetic 1 1 1 Synthetic Rescue
EMA35 YCR100C Protein involved in protein sorting genetic 1 1 1 Synthetic Rescue
DUS1 YML080W Dihydrouridine synthase genetic 1 1 1 Synthetic Rescue
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis genetic 1 1 1 Synthetic Rescue
AIM39 YOL053W Protein of unknown function genetic 1 1 1 Synthetic Rescue
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 1 1 1 Synthetic Growth Defect
GAS3 YMR215W Putative 1,3-beta-glucanosyltransferase genetic 1 1 1 Synthetic Rescue
BNA2 YJR078W Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase genetic 1 1 1 Synthetic Rescue
AGE1 YDR524C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector genetic 1 1 1 Synthetic Rescue
DDP1 YOR163W Diadenosine and diphosphoinositol polyphosphate phosphatase genetic 1 1 1 Synthetic Rescue
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Synthetic Rescue
MSK1 YNL073W Mitochondrial lysine-tRNA synthetase genetic 1 1 1 Negative Genetic
CYC1 YJR048W Cytochrome c, isoform 1 genetic 1 1 1 Synthetic Rescue
MTM1 YGR257C Mitochondrial protein of the mitochondrial carrier family genetic 1 1 1 Synthetic Growth Defect
CWH43 YCR017C GPI lipid remodelase genetic 1 1 1 Synthetic Rescue
GUT2 YIL155C Mitochondrial glycerol-3-phosphate dehydrogenase genetic 1 1 1 Synthetic Rescue
ALO1 YML086C D-Arabinono-1,4-lactone oxidase genetic 1 1 1 Synthetic Rescue
HPA3 YEL066W D-Amino acid N-acetyltransferase that detoxifies D-amino acids genetic 1 1 1 Synthetic Rescue
MRX18 YBR056W Putative glycoside hydrolase of the mitochondrial intermembrane space genetic 1 1 1 Synthetic Rescue
APE4 YHR113W Cytoplasmic aspartyl aminopeptidase with possible vacuole function genetic 1 1 1 Synthetic Rescue
CYC2 YOR037W Mitochondrial peripheral inner membrane protein genetic 1 1 1 Synthetic Growth Defect
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Synthetic Growth Defect
FPY1 YMR178W FAD pyrophosphatase genetic 1 1 1 Synthetic Rescue
CIS3 YJL158C Mannose-containing glycoprotein constituent of the cell wall genetic 1 1 1 Synthetic Rescue
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p genetic 1 1 1 Synthetic Rescue
FCY2 YER056C Purine-cytosine permease genetic 1 1 1 Synthetic Rescue
LGE1 YPL055C Protein involved in histone H2B ubiquitination physical 1 1 1 Affinity Capture-MS
FRM2 YCL026C-A Type II nitroreductase, using NADH as reductant genetic 1 1 1 Synthetic Rescue
CPR4 YCR069W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Synthetic Rescue
ADK2 YER170W Mitochondrial adenylate kinase genetic 1 1 1 Synthetic Rescue
LYP1 YNL268W Lysine permease genetic 1 1 1 Synthetic Rescue
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Synthetic Rescue
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER genetic 1 1 1 Synthetic Rescue
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Synthetic Growth Defect
CTT1 YGR088W Cytosolic catalase T genetic 1 1 1 Synthetic Rescue
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type genetic 1 1 1 Synthetic Rescue
ATG15 YCR068W Phospholipase genetic 1 1 1 Synthetic Rescue
AMD2 YDR242W Putative amidase genetic 1 1 1 Synthetic Rescue
IRC24 YIR036C Putative benzil reductase genetic 1 1 1 Synthetic Rescue
BUD16 YEL029C Putative pyridoxal kinase genetic 1 1 1 Synthetic Growth Defect
FRE5 YOR384W Putative ferric reductase with similarity to Fre2p genetic 1 1 1 Synthetic Rescue
FIT3 YOR383C Mannoprotein that is incorporated into the cell wall genetic 1 1 1 Synthetic Rescue
EMI1 YDR512C Non-essential protein of unknown function genetic 1 1 1 Synthetic Rescue
ATO2 YNR002C Putative transmembrane protein involved in export of ammonia genetic 1 1 1 Synthetic Rescue
HAL1 YPR005C Cytoplasmic protein involved in halotolerance genetic 1 1 1 Synthetic Rescue
ELO1 YJL196C Elongase I, medium-chain acyl elongase genetic 1 1 1 Synthetic Growth Defect
MTL1 YGR023W Putative plasma membrane sensor genetic 1 1 1 Synthetic Rescue
IML2 YJL082W Protein required for clearance of inclusion bodies genetic 1 1 1 Synthetic Rescue
APT2 YDR441C Potential adenine phosphoribosyltransferase genetic 1 1 1 Synthetic Rescue
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Negative Genetic
GPM3 YOL056W Nonfunctional homolog of Gpm1p phosphoglycerate mutase genetic 1 1 1 Synthetic Rescue
GRE2 YOL151W 3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase genetic 1 1 1 Synthetic Rescue
ATH1 YPR026W Acid trehalase required for utilization of extracellular trehalose genetic 1 1 1 Synthetic Rescue
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 1 1 1 Synthetic Rescue
DNF3 YMR162C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Synthetic Rescue
MTC3 YGL226W Protein of unknown function genetic 1 1 1 Synthetic Rescue
MRPL50 YNR022C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
LIH1 YJR107W Putative lipase genetic 1 1 1 Synthetic Rescue
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Synthetic Rescue
MRK1 YDL079C Glycogen synthase kinase 3 (GSK-3) homolog genetic 1 1 1 Synthetic Rescue
GRX6 YDL010W Cis-Golgi localized monothiol glutaredoxin, binds Fe-S cluster genetic 1 1 1 Synthetic Rescue
IRC18 YJL037W Protein involved in outer spore wall assembly genetic 1 1 1 Synthetic Rescue
MTE1 YGR042W Protein of unknown function genetic 1 1 1 Synthetic Rescue
LOG1 YJL055W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
MPC2 YHR162W Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) genetic 1 1 1 Synthetic Rescue
LMO1 YLL007C Homolog of mammalian ELMO (Engulfment and celL MOtility) genetic 1 1 1 Synthetic Growth Defect
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Synthetic Rescue
AGC1 YPR021C Mitochondrial amino acid transporter genetic 1 1 1 Synthetic Rescue
EFM4 YIL064W Lysine methyltransferase genetic 1 1 1 Synthetic Rescue
JHD1 YER051W JmjC domain family histone demethylase specific for H3-K36 genetic 1 1 1 Synthetic Rescue
LPX1 YOR084W Peroxisomal matrix-localized lipase genetic 1 1 1 Synthetic Growth Defect
ICY1 YMR195W Protein of unknown function genetic 1 1 1 Synthetic Rescue
ECM18 YDR125C Protein of unknown function genetic 1 1 1 Synthetic Rescue
MAK32 YCR019W Protein necessary for stability of L-A dsRNA-containing particles genetic 1 1 1 Synthetic Rescue
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum genetic 1 1 1 Synthetic Rescue
CLD1 YGR110W Mitochondrial cardiolipin-specific phospholipase genetic 1 1 1 Synthetic Growth Defect
ECM34 YHL043W Protein of unknown function genetic 1 1 1 Synthetic Rescue
DCV1 YFR012W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ALE1 YOR175C Broad-specificity lysophospholipid acyltransferase genetic 1 1 1 Synthetic Rescue
AIM19 YIL087C Protein of unknown function genetic 1 1 1 Synthetic Rescue
DIA3 YDL024C Protein of unknown function genetic 1 1 1 Synthetic Rescue
AVT7 YIL088C Vacuolar amino acid transporter genetic 1 1 1 Synthetic Rescue
GCV2 YMR189W P subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Synthetic Rescue
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Synthetic Growth Defect
ITR2 YOL103W Myo-inositol transporter genetic 1 1 1 Synthetic Rescue
HXT8 YJL214W Protein of unknown function with similarity to hexose transporters genetic 1 1 1 Synthetic Growth Defect
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Synthetic Growth Defect
NFT1 YKR103W Putative transporter of the MRP subfamily genetic 1 1 1 Synthetic Rescue
GAS4 YOL132W 1,3-beta-glucanosyltransferase genetic 1 1 1 Synthetic Rescue
MPM1 YJL066C Mitochondrial intermembrane space protein of unknown function genetic 1 1 1 Synthetic Rescue
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Synthetic Rescue
ENV9 YOR246C Conserved oxidoreductase involved in lipid droplet morphology genetic 1 1 1 Synthetic Rescue
ECT1 YGR007W Ethanolamine-phosphate cytidylyltransferase genetic 1 1 1 Synthetic Rescue
AIM10 YER087W Protein with similarity to tRNA synthetases genetic 1 1 1 Synthetic Growth Defect
IMA1 YGR287C Major isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase) genetic 1 1 1 Synthetic Rescue
AIM33 YML087C Protein of unknown function, highly conserved across species genetic 1 1 1 Synthetic Rescue
MRX19 YDL183C Protein that may form an active mitochondrial KHE system genetic 1 1 1 Synthetic Rescue
NNT1 YLR285W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Synthetic Rescue
CTS2 YDR371W Putative chitinase genetic 1 1 1 Synthetic Rescue
EAT1 YGR015C Ethanol acetyltransferase genetic 1 1 1 Synthetic Rescue
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Synthetic Growth Defect
IAH1 YOR126C Isoamyl acetate-hydrolyzing esterase genetic 1 1 1 Synthetic Rescue
AIF1 YNR074C Mitochondrial cell death effector genetic 1 1 1 Synthetic Rescue
HMS2 YJR147W Protein with similarity to heat shock transcription factors genetic 1 1 1 Synthetic Rescue
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase genetic 1 1 1 Synthetic Rescue
EMP65 YER140W Integral membrane protein of the ER genetic 1 1 1 Synthetic Growth Defect
FDC1 YDR539W Ferulic acid decarboxylase genetic 1 1 1 Synthetic Rescue
CWP1 YKL096W Cell wall mannoprotein that localizes to birth scars of daughter cells genetic 1 1 1 Synthetic Rescue
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Synthetic Rescue
MRX20 YFR045W Putative mitochondrial transport protein genetic 1 1 1 Synthetic Growth Defect
ICT1 YLR099C Lysophosphatidic acid acyltransferase genetic 1 1 1 Synthetic Rescue
MCH5 YOR306C Plasma membrane riboflavin transporter genetic 1 1 1 Synthetic Rescue
DBR1 YKL149C RNA lariat debranching enzyme genetic 1 1 1 Positive Genetic
MRX11 YPL041C Protein that associates with mitochondrial ribosome genetic 1 1 1 Synthetic Growth Defect
AAT1 YKL106W Mitochondrial aspartate aminotransferase genetic 1 1 1 Synthetic Rescue
FRE7 YOL152W Putative ferric reductase with similarity to Fre2p genetic 1 1 1 Synthetic Rescue
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Synthetic Rescue
IRS4 YKR019C EH domain-containing protein genetic 1 1 1 Synthetic Growth Defect
GRE1 YPL223C Hydrophilin essential in desiccation-rehydration process genetic 1 1 1 Synthetic Rescue
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 1 1 1 Synthetic Rescue
ECM8 YBR076W Non-essential protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MNL2 YLR057W Putative mannosidase involved in ER-associated protein degradation genetic 1 1 1 Synthetic Rescue