| RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
physical |
38 |
8 |
32 |
Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Co-crystal Structure, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Co-purification, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Co-purification, Affinity Capture-Western, Reconstituted Complex |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
physical |
34 |
7 |
30 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Co-purification, PCA, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Co-purification, Affinity Capture-Western |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
33 |
5 |
26 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Co-purification |
| RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
physical |
29 |
5 |
23 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Co-purification, Reconstituted Complex |
| RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
28 |
5 |
23 |
Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-purification, Affinity Capture-Western, Reconstituted Complex |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
physical |
27 |
4 |
24 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Reconstituted Complex, Co-purification |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
24 |
5 |
20 |
Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Co-purification |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
23 |
5 |
22 |
Affinity Capture-Western, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification, Reconstituted Complex |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
23 |
4 |
22 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-purification, Affinity Capture-Western |
| RPN3 |
YER021W |
Essential non-ATPase regulatory subunit of the 26S proteasome lid |
physical |
23 |
4 |
22 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Reconstituted Complex, Co-purification |
| RPN9 |
YDR427W |
Non-ATPase regulatory subunit of the 26S proteasome |
physical |
22 |
5 |
21 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Reconstituted Complex, Co-purification |
| RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
physical |
21 |
4 |
20 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Reconstituted Complex, Co-purification |
| RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
20 |
4 |
19 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-purification |
| RPN2 |
YIL075C |
Subunit of the 26S proteasome |
physical |
20 |
5 |
18 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Co-purification |
| RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
19 |
5 |
18 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Co-purification |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
physical |
18 |
4 |
18 |
Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
18 |
4 |
17 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-purification |
| PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
physical |
13 |
4 |
11 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification |
| PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
physical |
12 |
3 |
12 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS |
| SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
physical |
12 |
3 |
10 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification |
| UBI4 |
YLL039C |
Ubiquitin |
physical |
11 |
5 |
9 |
Affinity Capture-Western, Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Biochemical Activity, Co-crystal Structure, Biochemical Activity, Biochemical Activity, Biochemical Activity |
| RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
physical |
10 |
2 |
10 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
| SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
physical |
10 |
4 |
8 |
Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS |
| PRE5 |
YMR314W |
Alpha 6 subunit of the 20S proteasome |
physical |
10 |
4 |
8 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS |
| PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
physical |
10 |
4 |
8 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS |
| PRE8 |
YML092C |
Alpha 2 subunit of the 20S proteasome |
physical |
10 |
4 |
8 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
physical |
10 |
4 |
8 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS |
| PUP2 |
YGR253C |
Alpha 5 subunit of the 20S proteasome |
physical |
10 |
4 |
8 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS |
| RPN13 |
YLR421C |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
physical |
9 |
4 |
9 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS |
| PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
physical |
9 |
3 |
9 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-Western |
| NAS6 |
YGR232W |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
physical |
9 |
3 |
6 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex |
| ECM29 |
YHL030W |
Scaffold protein |
physical |
9 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
| PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
physical |
8 |
3 |
8 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification |
| DSK2 |
YMR276W |
Nuclear-enriched ubiquitin-like polyubiquitin-binding protein |
physical |
8 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western |
| PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
physical |
7 |
3 |
7 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification |
| PRE3 |
YJL001W |
Beta 1 subunit of the 20S proteasome |
physical |
7 |
3 |
7 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification |
| PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
physical |
7 |
3 |
7 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
physical |
7 |
3 |
7 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
5 |
2 |
5 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| RPN14 |
YGL004C |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
physical |
5 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Co-crystal Structure, Co-purification |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-RNA, Affinity Capture-RNA |
| URA7 |
YBL039C |
Major CTP synthase isozyme (see also URA8) |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
4 |
3 |
3 |
Phenotypic Suppression, Positive Genetic, Positive Genetic, Negative Genetic |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
| CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
4 |
2 |
2 |
Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic |
| RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
4 |
2 |
2 |
Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
4 |
2 |
2 |
Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic |
| RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
4 |
2 |
2 |
Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic |
| CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
4 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
| SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Lethality, Negative Genetic |
| SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
| RUB1 |
YDR139C |
Ubiquitin-like protein with similarity to mammalian NEDD8 |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect |
| DDI1 |
YER143W |
Aspartic-type endopeptidase |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
| MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Lethality, Negative Genetic |
| ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| KAP123 |
YER110C |
Karyopherin beta |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| PAB1 |
YER165W |
Poly(A) binding protein |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SEC53 |
YFL045C |
Phosphomannomutase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| TIF2 |
YJL138C |
Translation initiation factor eIF4A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RPS5 |
YJR123W |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SAH1 |
YER043C |
S-adenosyl-L-homocysteine hydrolase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| TDH1 |
YJL052W |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| TAL1 |
YLR354C |
Transaldolase, enzyme in the non-oxidative pentose phosphate pathway |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| THS1 |
YIL078W |
Threonyl-tRNA synthetase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| VAS1 |
YGR094W |
Mitochondrial and cytoplasmic valyl-tRNA synthetase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| YHB1 |
YGR234W |
Nitric oxide oxidoreductase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SER1 |
YOR184W |
3-phosphoserine aminotransferase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| ENO1 |
YGR254W |
Enolase I, a phosphopyruvate hydratase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| FBA1 |
YKL060C |
Fructose 1,6-bisphosphate aldolase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| PGK1 |
YCR012W |
3-phosphoglycerate kinase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| PDC1 |
YLR044C |
Major of three pyruvate decarboxylase isozymes |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| GND1 |
YHR183W |
6-phosphogluconate dehydrogenase (decarboxylating) |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| HSP104 |
YLL026W |
Disaggregase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| HEF3 |
YNL014W |
Translational elongation factor EF-3 |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| CDC60 |
YPL160W |
Cytosolic leucyl tRNA synthetase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| ERG20 |
YJL167W |
Farnesyl pyrophosphate synthetase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| CDC19 |
YAL038W |
Pyruvate kinase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| ASN1 |
YPR145W |
Asparagine synthetase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| LEU1 |
YGL009C |
Isopropylmalate isomerase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| LYS21 |
YDL131W |
Homocitrate synthase isozyme |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| FAS1 |
YKL182W |
Beta subunit of fatty acid synthetase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| MOT2 |
YER068W |
Ubiquitin-protein ligase subunit of the CCR4-NOT complex |
physical |
3 |
3 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex |
| STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Dosage Rescue |
| SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| YOX1 |
YML027W |
Homeobox transcriptional repressor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TMC1 |
YOR052C |
AN1-type zinc finger protein, effector of proteotoxic stress response |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HHF1 |
YBR009C |
Histone H4 |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPL11B |
YGR085C |
Ribosomal 60S subunit protein L11B |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PUP2 |
YGR253C |
Alpha 5 subunit of the 20S proteasome |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
3 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-Western, Co-fractionation |
| STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
physical |
2 |
2 |
2 |
Two-hybrid, Reconstituted Complex |
| RRI1 |
YDL216C |
Catalytic subunit of the COP9 signalosome (CSN) complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Positive Genetic |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
2 |
2 |
2 |
Affinity Capture-RNA, Affinity Capture-MS |
| HSM3 |
YBR272C |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| CMD1 |
YBR109C |
Calmodulin |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
| GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Dosage Rescue |
| DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL30 |
YGL030W |
Ribosomal 60S subunit protein L30 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MCM21 |
YDR318W |
Component of the kinetochore sub-complex COMA |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MES1 |
YGR264C |
Methionyl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FUN12 |
YAL035W |
Translation initiation factor eIF5B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPA135 |
YPR010C |
RNA polymerase I second largest subunit A135 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ILS1 |
YBL076C |
Cytoplasmic isoleucine-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SOK1 |
YDR006C |
Protein of unknown function |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YRB1 |
YDR002W |
Ran GTPase binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ZEO1 |
YOL109W |
Peripheral membrane protein of the plasma membrane |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TMA19 |
YKL056C |
Protein that associates with ribosomes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TIF3 |
YPR163C |
Translation initiation factor eIF-4B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TSL1 |
YML100W |
Large subunit of trehalose 6-phosphate synthase/phosphatase complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SSZ1 |
YHR064C |
Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SUP45 |
YBR143C |
Polypeptide release factor (eRF1) in translation termination |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ZUO1 |
YGR285C |
Ribosome-associated chaperone |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TIF5 |
YPR041W |
Translation initiation factor eIF5 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TPD3 |
YAL016W |
Regulatory subunit A of the heterotrimeric PP2A complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TUB2 |
YFL037W |
Beta-tubulin |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SAM2 |
YDR502C |
S-adenosylmethionine synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| UGP1 |
YKL035W |
UDP-glucose pyrophosphorylase (UGPase) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SEC4 |
YFL005W |
Rab family GTPase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TUB1 |
YML085C |
Alpha-tubulin |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TUF1 |
YOR187W |
Mitochondrial translation elongation factor Tu (EF-Tu) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS9B |
YBR189W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| UBA1 |
YKL210W |
Ubiquitin activating enzyme (E1) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TRP2 |
YER090W |
Anthranilate synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SES1 |
YDR023W |
Cytosolic seryl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TPI1 |
YDR050C |
Triose phosphate isomerase, abundant glycolytic enzyme |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TPS3 |
YMR261C |
Regulatory subunit of trehalose-6-phosphate synthase/phosphatase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SPE3 |
YPR069C |
Spermidine synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TKL1 |
YPR074C |
Transketolase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SAR1 |
YPL218W |
ARF family GTPase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YDR341C |
YDR341C |
Arginyl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YMR099C |
YMR099C |
Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TRX2 |
YGR209C |
Cytoplasmic thioredoxin isoenzyme |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YLR179C |
YLR179C |
Protein of unknown function with similarity to Tfs1p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TDH2 |
YJR009C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TRP3 |
YKL211C |
Indole-3-glycerol-phosphate synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SEC21 |
YNL287W |
Gamma subunit of coatomer |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RTN1 |
YDR233C |
Reticulon protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TRP5 |
YGL026C |
Tryptophan synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SER3 |
YER081W |
3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS26B |
YER131W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS17B |
YDR447C |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| URA5 |
YML106W |
Major orotate phosphoribosyltransferase (OPRTase) isozyme |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YBL005W-A |
YBL005W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSA3 |
YBL075C |
ATPase involved in protein folding and the response to stress |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SSA4 |
YER103W |
Heat shock protein that is highly induced upon stress |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
2 |
1 |
2 |
Reconstituted Complex, Reconstituted Complex |
| RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBS1 |
YBR165W |
Ubiquitin-conjugating enzyme suppressor that regulates Cdc34p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPP1B |
YDL130W |
Ribosomal protein P1 beta |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPP1A |
YDL081C |
Ribosomal stalk protein P1 alpha |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPS29B |
YDL061C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YBP2 |
YGL060W |
Central kinetochore associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| WSS1 |
YHR134W |
SUMO-ligase and SUMO-targeted metalloprotease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSP2 |
YOR242C |
Sporulation specific protein that localizes to the spore wall |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VIK1 |
YPL253C |
Protein that forms a kinesin-14 heterodimeric motor with Kar3p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ULA1 |
YPL003W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RLI1 |
YDR091C |
Essential Fe-S protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PUF6 |
YDR496C |
Pumilio-homology domain protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| HGH1 |
YGR187C |
Chaperone protein for translation factor eEF2 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ADE13 |
YLR359W |
Adenylosuccinate lyase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| BAT1 |
YHR208W |
Mitochondrial branched-chain amino acid (BCAA) aminotransferase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CAR1 |
YPL111W |
Arginase, catabolizes arginine to ornithine and urea |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CPR1 |
YDR155C |
Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CYS4 |
YGR155W |
Cystathionine beta-synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GLY1 |
YEL046C |
Threonine aldolase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| HIS4 |
YCL030C |
Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CLU1 |
YMR012W |
Subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARB1 |
YER036C |
ATPase of the ATP-binding cassette (ABC) family |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GLT1 |
YDL171C |
NAD(+)-dependent glutamate synthase (GOGAT) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NMD3 |
YHR170W |
Protein involved in nuclear export of the large ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| AHA1 |
YDR214W |
Co-chaperone that binds Hsp82p and activates its ATPase activity |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LAT1 |
YNL071W |
Dihydrolipoamide acetyltransferase component (E2) of the PDC |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PRO2 |
YOR323C |
Gamma-glutamyl phosphate reductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MVD1 |
YNR043W |
Mevalonate pyrophosphate decarboxylase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CPA2 |
YJR109C |
Large subunit of carbamoyl phosphate synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GPM1 |
YKL152C |
Tetrameric phosphoglycerate mutase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ADE57 |
YGL234W |
Bifunctional enzyme of 'de novo' purine nucleotide pathway |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PIL1 |
YGR086C |
Eisosome core component |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PGI1 |
YBR196C |
Glycolytic enzyme phosphoglucose isomerase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CAM1 |
YPL048W |
One of two isoforms of the gamma subunit of eEF1B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| EFB1 |
YAL003W |
Translation elongation factor 1 beta |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GLN1 |
YPR035W |
Glutamine synthetase (GS) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ATP2 |
YJR121W |
Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ABP1 |
YCR088W |
Actin-binding protein of the cortical actin cytoskeleton |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LSP1 |
YPL004C |
Eisosome core component |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ADO1 |
YJR105W |
Adenosine kinase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARF1 |
YDL192W |
ADP-ribosylation factor |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AHP1 |
YLR109W |
Thiol-specific peroxiredoxin |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CMP2 |
YML057W |
Calcineurin A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GSP1 |
YLR293C |
Ran GTPase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| FAA4 |
YMR246W |
Long chain fatty acyl-CoA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| OYE2 |
YHR179W |
Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PST2 |
YDR032C |
FMN-dependent NAD(P)H:quinone oxidoreductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ILV5 |
YLR355C |
Acetohydroxyacid reductoisomerase and mtDNA binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ADK1 |
YDR226W |
Adenylate kinase, required for purine metabolism |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GPD1 |
YDL022W |
NAD-dependent glycerol-3-phosphate dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PET9 |
YBL030C |
Major ADP/ATP carrier of the mitochondrial inner membrane |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LIA1 |
YJR070C |
Deoxyhypusine hydroxylase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PRO3 |
YER023W |
Delta 1-pyrroline-5-carboxylate reductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| APT1 |
YML022W |
Adenine phosphoribosyltransferase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DLD3 |
YEL071W |
2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| FUM1 |
YPL262W |
Fumarase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GRS1 |
YBR121C |
Cytoplasmic and mitochondrial glycyl-tRNA synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PDC5 |
YLR134W |
Minor isoform of pyruvate decarboxylase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MET6 |
YER091C |
Cobalamin-independent methionine synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| FRS2 |
YFL022C |
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NPA3 |
YJR072C |
Member of the conserved GPN-loop GTPase family |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PBA1 |
YLR199C |
Protein involved in 20S proteasome assembly |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FAA1 |
YOR317W |
Long chain fatty acyl-CoA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| APA1 |
YCL050C |
AP4A phosphorylase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CPA1 |
YOR303W |
Small subunit of carbamoyl phosphate synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RNR1 |
YER070W |
Major isoform of large subunit of ribonucleotide-diphosphate reductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ALD5 |
YER073W |
Mitochondrial aldehyde dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARG1 |
YOL058W |
Arginosuccinate synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARA1 |
YBR149W |
NADP+ dependent arabinose dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ADE6 |
YGR061C |
Formylglycinamidine-ribonucleotide (FGAM)-synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| APE2 |
YKL157W |
Aminopeptidase yscII |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| EXG1 |
YLR300W |
Major exo-1,3-beta-glucanase of the cell wall |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PRS1 |
YKL181W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DDI1 |
YER143W |
Aspartic-type endopeptidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ARG3 |
YJL088W |
Ornithine carbamoyltransferase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GDH1 |
YOR375C |
NADP(+)-dependent glutamate dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LEU4 |
YNL104C |
Alpha-isopropylmalate synthase (2-isopropylmalate synthase) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MSN5 |
YDR335W |
Karyopherin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL9A |
YGL147C |
Ribosomal 60S subunit protein L9A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ELO3 |
YLR372W |
Elongase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ESC1 |
YMR219W |
Protein involved in telomeric silencing |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| HCH1 |
YNL281W |
Heat shock protein regulator |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| AZF1 |
YOR113W |
Zinc-finger transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL1B |
YGL135W |
Ribosomal 60S subunit protein L1B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ATP1 |
YBL099W |
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL11B |
YGR085C |
Ribosomal 60S subunit protein L11B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DYS1 |
YHR068W |
Deoxyhypusine synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL13A |
YDL082W |
Ribosomal 60S subunit protein L13A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL14B |
YHL001W |
Ribosomal 60S subunit protein L14B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL7A |
YGL076C |
Ribosomal 60S subunit protein L7A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL21A |
YBR191W |
Ribosomal 60S subunit protein L21A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ASN2 |
YGR124W |
Asparagine synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARO8 |
YGL202W |
Aromatic aminotransferase I |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| FUR1 |
YHR128W |
Uracil phosphoribosyltransferase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CIT1 |
YNR001C |
Mitochondrial citrate synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ERG2 |
YMR202W |
C-8 sterol isomerase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| EHT1 |
YBR177C |
Octanoyl-CoA:ethanol acyltransferase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GLK1 |
YCL040W |
Glucokinase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LYS20 |
YDL182W |
Homocitrate synthase isozyme and functions in DNA repair |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARI1 |
YGL157W |
NADPH-dependent aldehyde reductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARG56 |
YER069W |
Acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ADE16 |
YLR028C |
Enzyme of 'de novo' purine biosynthesis |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| BNA1 |
YJR025C |
3-hydroxyanthranilic acid dioxygenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MSC7 |
YHR039C |
Protein of unknown function |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GRE3 |
YHR104W |
Aldose reductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| FRD1 |
YEL047C |
Soluble fumarate reductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| IDP1 |
YDL066W |
Mitochondrial NADP-specific isocitrate dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GLN4 |
YOR168W |
Glutamine tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LAP3 |
YNL239W |
Cysteine aminopeptidase with homocysteine-thiolactonase activity |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PSA1 |
YDL055C |
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL20A |
YMR242C |
Ribosomal 60S subunit protein L20A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GUA1 |
YMR217W |
GMP synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PCM1 |
YEL058W |
Essential N-acetylglucosamine-phosphate mutase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PAN5 |
YHR063C |
2-dehydropantoate 2-reductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CYC1 |
YJR048W |
Cytochrome c, isoform 1 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PYP1 |
YNL010W |
Sugar alcohol phosphatase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ALO1 |
YML086C |
D-Arabinono-1,4-lactone oxidase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| QNS1 |
YHR074W |
Glutamine-dependent NAD(+) synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PNC1 |
YGL037C |
Nicotinamidase that converts nicotinamide to nicotinic acid |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| HXT3 |
YDR345C |
Low affinity glucose transporter of the major facilitator superfamily |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| OAC1 |
YKL120W |
Mitochondrial inner membrane transporter |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MET5 |
YJR137C |
Sulfite reductase beta subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| HTS1 |
YPR033C |
Cytoplasmic and mitochondrial histidine tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL12B |
YDR418W |
Ribosomal 60S subunit protein L12B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| HIS7 |
YBR248C |
Imidazole glycerol phosphate synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ENV9 |
YOR246C |
Conserved oxidoreductase involved in lipid droplet morphology |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPN3 |
YER021W |
Essential non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPN2 |
YIL075C |
Subunit of the 26S proteasome |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| UBI4 |
YLL039C |
Ubiquitin |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| UBC9 |
YDL064W |
SUMO-conjugating enzyme involved in the Smt3p conjugation pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YJU2 |
YKL095W |
Essential protein required for pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| UBP1 |
YDL122W |
Ubiquitin-specific protease |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPS21A |
YKR057W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPS28B |
YLR264W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YML108W |
YML108W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TFB5 |
YDR079C-A |
Component of RNA polymerase II general transcription factor TFIIH |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
1 |
Synthetic Haploinsufficiency, Synthetic Haploinsufficiency |
| PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRE5 |
YMR314W |
Alpha 6 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| PRE8 |
YML092C |
Alpha 2 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BCP1 |
YDR361C |
Essential nuclear chaperone for ribosomal protein Rpl23p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC53 |
YDL132W |
Cullin |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RAD55 |
YDR076W |
Protein that stimulates strand exchange |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPL9B |
YNL067W |
Ribosomal 60S subunit protein L9B |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RDS3 |
YPR094W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| IRC25 |
YLR021W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RNY1 |
YPL123C |
Vacuolar RNase of the T(2) family |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CHM7 |
YJL049W |
Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC40 |
YDR364C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHL4 |
YDR254W |
Outer kinetochore protein required for chromosome stability |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IKI3 |
YLR384C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOG1 |
YPL093W |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCD6 |
YDR211W |
Catalytic epsilon subunit of the translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP9 |
YJL010C |
Essential subunit of U3-containing 90S preribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EMW1 |
YNL313C |
Essential conserved protein with a role in cell wall integrity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC42 |
YLR229C |
Small rho-like GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAT3 |
YPR131C |
Catalytic subunit of the NatB N-terminal acetyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL3 |
YDR432W |
RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARX1 |
YDR101C |
Nuclear export factor for the ribosomal pre-60S subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SPG5 |
YMR191W |
Protein required for proteasome assembly during quiescence |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRS1 |
YOR294W |
Essential protein that binds ribosomal protein L11 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SQT1 |
YIR012W |
Specific assembly chaperone for ribosomal protein Rpl10p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAE1 |
YBR261C |
AdoMet-dependent proline methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUP45 |
YBR143C |
Polypeptide release factor (eRF1) in translation termination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URA2 |
YJL130C |
Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMC1 |
YPR058W |
Secondary mitochondrial inner membrane glycine transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SHB17 |
YKR043C |
Sedoheptulose bisphosphatase involved in riboneogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHM2 |
YLR058C |
Cytosolic serine hydroxymethyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIM23 |
YNR017W |
Essential component of the TIM23 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP43 |
YCR035C |
Exosome non-catalytic core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC13 |
YLR208W |
Structural component of 3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SER33 |
YIL074C |
3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SFA1 |
YDL168W |
Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKP1 |
YDR328C |
Evolutionarily conserved kinetochore protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNZ1 |
YMR096W |
Subunit of a two-component pyridoxal-5'-phosphate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SRP54 |
YPR088C |
Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSD1 |
YDR293C |
Translational repressor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SVL3 |
YPL032C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SXM1 |
YDR395W |
Nuclear transport factor (karyopherin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TFG1 |
YGR186W |
TFIIF (Transcription Factor II) largest subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| THR1 |
YHR025W |
Homoserine kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| THR4 |
YCR053W |
Threonine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TMA20 |
YER007C-A |
Protein of unknown function that associates with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TMA22 |
YJR014W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TPA1 |
YER049W |
Prolyl hydroxylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TRM8 |
YDL201W |
Catalytic subunit of a tRNA methyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TRR1 |
YDR353W |
Cytoplasmic thioredoxin reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TRX1 |
YLR043C |
Cytoplasmic thioredoxin isoenzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TYS1 |
YGR185C |
Cytoplasmic tyrosyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP14 |
YBR058C |
Ubiquitin-specific protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VMA10 |
YHR039C-A |
Subunit G of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VMA4 |
YOR332W |
Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VMA5 |
YKL080W |
Subunit C of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VMA6 |
YLR447C |
Subunit d of the V0 integral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| XPT1 |
YJR133W |
Xanthine-guanine phosphoribosyl transferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YAR010C |
YAR010C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YBL005W-B |
YBL005W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YBP1 |
YBR216C |
Protein involved in cellular response to oxidative stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YBR012W-A |
YBR012W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YBR012W-B |
YBR012W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YBR053C |
YBR053C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YCP4 |
YCR004C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YCR051W |
YCR051W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDL124W |
YDL124W |
NADPH-dependent alpha-keto amide reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDR098C-A |
YDR098C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDR170W-A |
YDR170W-A |
Retrotransposon TYA Gag gene |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDR210C-C |
YDR210C-C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDR210C-D |
YDR210C-D |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDR261C-C |
YDR261C-C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDR316W-A |
YDR316W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDR316W-B |
YDR316W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDR365W-A |
YDR365W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YER137C-A |
YER137C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YER138C |
YER138C |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YER159C-A |
YER159C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YER160C |
YER160C |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YET3 |
YDL072C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YGL039W |
YGL039W |
Aldehyde reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YGR027W-A |
YGR027W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YGR027W-B |
YGR027W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YGR038C-A |
YGR038C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YGR054W |
YGR054W |
Eukaryotic initiation factor eIF2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YGR109W-A |
YGR109W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YGR161C-C |
YGR161C-C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YGR161C-D |
YGR161C-D |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YHI9 |
YHR029C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YHM2 |
YMR241W |
Citrate and oxoglutarate carrier protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YHR214C-C |
YHR214C-C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YIL108W |
YIL108W |
Putative metalloendopeptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YIP3 |
YNL044W |
Protein localized to COPII vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YJR026W |
YJR026W |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YJR028W |
YJR028W |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YJR029W |
YJR029W |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YKR018C |
YKR018C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YLR035C-A |
YLR035C-A |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YLR157C-A |
YLR157C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YLR225C |
YLR225C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YLR227W-A |
YLR227W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YLR256W-A |
YLR256W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YML040W |
YML040W |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YML045W-A |
YML045W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YMR027W |
YMR027W |
A metal-dependent phosphatase, part of the DUF89 protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YMR045C |
YMR045C |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YMR046C |
YMR046C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YMR050C |
YMR050C |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YMR051C |
YMR051C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YMR315W |
YMR315W |
Protein with NADP(H) oxidoreductase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YNL054W-A |
YNL054W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YNL054W-B |
YNL054W-B |
TyB Gag-Pol protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YNL108C |
YNL108C |
Protein phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YNL208W |
YNL208W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YNL284C-A |
YNL284C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YNL284C-B |
YNL284C-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YOL103W-A |
YOL103W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YOL103W-B |
YOL103W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YOP1 |
YPR028W |
Reticulon-interacting protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YOR142W-A |
YOR142W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YOR142W-B |
YOR142W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TUM1 |
YOR251C |
Rhodanese domain sulfur transferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YOR283W |
YOR283W |
Phosphatase with a broad substrate specificity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPK1 |
YKL126W |
S/T protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPL088W |
YPL088W |
Putative aryl alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPL225W |
YPL225W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPL257W-A |
YPL257W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPR1 |
YDR368W |
NADPH-dependent aldo-keto reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPR137C-A |
YPR137C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPR148C |
YPR148C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPR158C-C |
YPR158C-C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPR158W-A |
YPR158W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT1 |
YFL038C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT31 |
YER031C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YRB2 |
YIL063C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YSA1 |
YBR111C |
Nudix hydrolase family member with ADP-ribose pyrophosphatase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRP1 |
YNL189W |
Karyopherin alpha homolog |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| UFO1 |
YML088W |
F-box receptor protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SIZ1 |
YDR409W |
SUMO E3 ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIF1 |
YKR059W |
Translation initiation factor eIF4A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RUB1 |
YDR139C |
Ubiquitin-like protein with similarity to mammalian NEDD8 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
physical |
1 |
1 |
1 |
Proximity Label-MS |
| TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP2B |
YDR382W |
Ribosomal protein P2 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SKI7 |
YOR076C |
GTP-binding protein that couples the Ski complex and exosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YCG1 |
YDR325W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOG2 |
YOR353C |
Key component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP42 |
YDL111C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC1 |
YDR177W |
Ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTR5 |
YEL035C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC97 |
YHR172W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPO31 |
YOR116C |
RNA polymerase III largest subunit C160 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCS4 |
YLR272C |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF11 |
YMR260C |
Translation initiation factor eIF1A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC29 |
YPL124W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCR090C |
YCR090C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS28A |
YOR167C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO11 |
YHL022C |
Meiosis-specific protein required for meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCL068C |
YCL068C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYO1 |
YDL063C |
Transport adaptor or symportin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RXT3 |
YDL076C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOS9 |
YDR057W |
ER quality-control lectin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWM1 |
YDR260C |
Subunit of the anaphase-promoting complex (APC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKI8 |
YGL213C |
Ski complex component and WD-repeat protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR122W |
YGR122W |
Protein that may be involved in pH regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHL008C |
YHL008C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS4A |
YJR145C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR154C-H |
YLR154C-H |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC12 |
YLR306W |
Enzyme that mediates the conjugation of Rub1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS29A |
YLR388W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKI2 |
YLR398C |
Ski complex component and putative RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM9 |
YML014W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR001C-A |
YMR001C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR175W-A |
YMR175W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL067W-B |
YNL067W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGP1 |
YNL160W |
Cell wall-related secretory glycoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT11 |
YNL304W |
Rab GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UAF30 |
YOR295W |
Subunit of UAF (upstream activation factor) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTA6 |
YPL074W |
Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL108W |
YPL108W |
Cytoplasmic protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDD4 |
YPR022C |
Putative transcription factor, as suggested by computational analysis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKI3 |
YPR189W |
Ski complex component and TPR protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMD2 |
YHR216W |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RBG2 |
YGR173W |
Protein with a role in translation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSG1 |
YGL099W |
Putative GTPase involved in 60S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KAP104 |
YBR017C |
Transportin or cytosolic karyopherin beta 2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KAP104 |
YBR017C |
Transportin or cytosolic karyopherin beta 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE4 |
YMR300C |
Phosphoribosylpyrophosphate amidotransferase (PRPPAT) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC2 |
YLR127C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC40 |
YBR234C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAF130 |
YGR134W |
Subunit of the CCR4-NOT transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERG26 |
YGL001C |
C-3 sterol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIX1 |
YHR197W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOG2 |
YNR053C |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHC1 |
YGL206C |
Clathrin heavy chain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ELP2 |
YGR200C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN2 |
YDR283C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDI1 |
YER136W |
GDP dissociation inhibitor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HRP1 |
YOL123W |
Subunit of cleavage factor I |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INP2 |
YMR163C |
Peroxisome-specific receptor important for peroxisome inheritance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRP7 |
YNL005C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRM1 |
YOR201C |
Ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPH1 |
YIR002C |
3'-5' DNA helicase involved in error-free bypass of DNA lesions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO80 |
YGL150C |
Nucleosome spacing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| INO80 |
YGL150C |
Nucleosome spacing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAP1 |
YKR002W |
Poly(A) polymerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BLM10 |
YFL007W |
Proteasome activator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PTC3 |
YBL056W |
Type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PAA1 |
YDR071C |
Polyamine acetyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| REF2 |
YDR195W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC3 |
YNL290W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE3 |
YGR204W |
Cytoplasmic trifunctional enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSN9 |
YDR179C |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PCI8 |
YIL071C |
Possible shared subunit of Cop9 signalosome (CSN) and eIF3 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CSI1 |
YMR025W |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE1 |
YGL238W |
Nuclear envelope protein that acts as a recycling factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUG1 |
YFR044C |
Cys-Gly metallo-di-peptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSB3 |
YFR024C-A |
Protein containing a C-terminal SH3 domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNA3 |
YJL060W |
Kynurenine aminotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DNM1 |
YLL001W |
Dynamin-related GTPase involved in mitochondrial organization |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CAR2 |
YLR438W |
L-ornithine transaminase (OTAse) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ACO1 |
YLR304C |
Aconitase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AKL1 |
YBR059C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NGL2 |
YMR285C |
Protein involved in 5.8S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PYC1 |
YGL062W |
Pyruvate carboxylase isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RNR2 |
YJL026W |
Ribonucleotide-diphosphate reductase (RNR), small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PLN1 |
YKR046C |
Perilipin, involved in formation and stability of lipid droplets |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GDE1 |
YPL110C |
Glycerophosphocholine (GroPCho) phosphodiesterase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARO4 |
YBR249C |
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRO1 |
YDR300C |
Gamma-glutamyl kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AAT2 |
YLR027C |
Cytosolic aspartate aminotransferase involved in nitrogen metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPD2 |
YOL059W |
NAD-dependent glycerol 3-phosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRS3 |
YHL011C |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CYC8 |
YBR112C |
General transcriptional co-repressor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CYC8 |
YBR112C |
General transcriptional co-repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAE1 |
YKL029C |
Mitochondrial malic enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIP1 |
YMR092C |
Actin cortical patch component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PDS1 |
YDR113C |
Securin |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ERG1 |
YGR175C |
Squalene epoxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HRT3 |
YLR097C |
Putative SCF-ubiquitin ligase F-box protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPP2 |
YER062C |
DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ADH3 |
YMR083W |
Mitochondrial alcohol dehydrogenase isozyme III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IMD4 |
YML056C |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APE1 |
YKL103C |
Vacuolar aminopeptidase yscI |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DSK2 |
YMR276W |
Nuclear-enriched ubiquitin-like polyubiquitin-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| HMF1 |
YER057C |
Member of the p14.5 protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GRS1 |
YBR121C |
Cytoplasmic and mitochondrial glycyl-tRNA synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPN3 |
YLR243W |
Putative GTPase with a role in biogenesis of RNA pol II and polIII |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HUL5 |
YGL141W |
Multiubiquitin chain assembly factor (E4) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| GRX1 |
YCL035C |
Glutathione-dependent disulfide oxidoreductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ISU1 |
YPL135W |
Conserved protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAG1 |
YER142C |
3-methyl-adenine DNA glycosylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAS2 |
YNL098C |
GTP-binding protein |
physical |
1 |
1 |
1 |
PCA |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCN2 |
YOR220W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PGM1 |
YKL127W |
Phosphoglucomutase, minor isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ILV2 |
YMR108W |
Acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RGI1 |
YER067W |
Protein involved in energy metabolism under respiratory conditions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARF2 |
YDL137W |
ADP-ribosylation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAP2 |
YBL091C |
Methionine aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FUB1 |
YCR076C |
Proteasome-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| DEF1 |
YKL054C |
RNAPII degradation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DEF1 |
YKL054C |
RNAPII degradation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LEM3 |
YNL323W |
Membrane protein of the plasma membrane and ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GBP2 |
YCL011C |
Poly(A+) RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CBR1 |
YIL043C |
Cytochrome b reductase and NADH-dependent reductase for Dph3p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ADH6 |
YMR318C |
NADPH-dependent medium chain alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRS2 |
YER099C |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MGT1 |
YDL200C |
DNA repair methyltransferase (6-O-methylguanine-DNA methylase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CUE5 |
YOR042W |
Ubiquitin-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM11 |
YDR446W |
Meiosis-specific protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DID4 |
YKL002W |
Class E Vps protein of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE2 |
YOR128C |
Phosphoribosylaminoimidazole carboxylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FMN1 |
YDR236C |
Riboflavin kinase, produces riboflavin monophosphate (FMN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIG1 |
YBR040W |
Integral membrane protein required for efficient mating |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LST7 |
YGR057C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEX21 |
YGR239C |
Peroxin required for peroxisomal matrix protein targeting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRM3 |
YPL192C |
Protein required for nuclear envelope fusion during karyogamy |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CHA4 |
YLR098C |
DNA binding transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KTI12 |
YKL110C |
Protein that plays a role in modification of tRNA wobble nucleosides |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET14 |
YKL001C |
Adenylylsulfate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NST1 |
YNL091W |
Translational inhibitor and suppressor of proteasome-assembly defects |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC15 |
YDR163W |
Non-essential protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IKI1 |
YHR187W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX5 |
YDR244W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NFI1 |
YOR156C |
SUMO E3 ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARP5 |
YNL059C |
Nuclear actin-related protein involved in chromatin remodeling |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRN1 |
YBL097W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MYO5 |
YMR109W |
One of two type I myosin motors |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PNG1 |
YPL096W |
Conserved peptide N-glycanase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PAM18 |
YLR008C |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEP7 |
YDR323C |
Adaptor protein involved in vesicle-mediated vacuolar protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPH2 |
YKL191W |
Protein required for synthesis of diphthamide |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KTI11 |
YBL071W-A |
Zn-ribbon protein that co-purifies with Dph1 and Dph2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MBF1 |
YOR298C-A |
Transcriptional coactivator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MOB1 |
YIL106W |
Component of the mitotic exit network |
physical |
1 |
1 |
1 |
Proximity Label-MS |
| MOB1 |
YIL106W |
Component of the mitotic exit network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESC2 |
YDR363W |
Sumo-like domain protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGD2 |
YFL047W |
GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BAT2 |
YJR148W |
Cytosolic branched-chain amino acid (BCAA) aminotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCP1 |
YHR042W |
NADP-cytochrome P450 reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMT1 |
YDL095W |
Protein O-mannosyltransferase of the ER membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMT4 |
YJR143C |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG10 |
YLL042C |
Conserved E2-like conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HBT1 |
YDL223C |
Shmoo tip protein, substrate of Hub1p ubiquitin-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERV14 |
YGL054C |
COPII-coated vesicle protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EFT1 |
YOR133W |
Elongation factor 2 (EF-2), also encoded by EFT2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL18B |
YNL301C |
Ribosomal 60S subunit protein L18B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PER33 |
YLR064W |
Protein that localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL14B |
YHL001W |
Ribosomal 60S subunit protein L14B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG5 |
YMR015C |
C-22 sterol desaturase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MEU1 |
YLR017W |
Methylthioadenosine phosphorylase (MTAP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MEU1 |
YLR017W |
Methylthioadenosine phosphorylase (MTAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRG1 |
YHR209W |
S-AdoMet-dependent methyltransferase involved in lipid homeostasis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSP26 |
YBR072W |
Small heat shock protein (sHSP) with chaperone activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FRA1 |
YLL029W |
Protein involved in negative regulation of iron regulon transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ASG7 |
YJL170C |
Protein that regulates signaling from G protein beta subunit Ste4p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CAN1 |
YEL063C |
Plasma membrane arginine permease |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MXR1 |
YER042W |
Methionine-S-sulfoxide reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE2 |
YDR483W |
Alpha1,2-mannosyltransferase of the Golgi |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRH1 |
YDR033W |
Protein that localizes primarily to the plasma membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NCE102 |
YPR149W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MET17 |
YLR303W |
O-acetyl homoserine-O-acetyl serine sulfhydrylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BDH1 |
YAL060W |
NAD-dependent (R,R)-butanediol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSP12 |
YFL014W |
Plasma membrane protein involved in maintaining membrane organization |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAP1 |
YLR244C |
Methionine aminopeptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IFA38 |
YBR159W |
Microsomal beta-keto-reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL43B |
YJR094W-A |
Ribosomal 60S subunit protein L43B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NTH1 |
YDR001C |
Neutral trehalase, degrades trehalose |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HXK1 |
YFR053C |
Hexokinase isoenzyme 1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FCF2 |
YLR051C |
Nucleolar protein involved in the early steps of 35S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GUK1 |
YDR454C |
Guanylate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ISD11 |
YER048W-A |
Cysteine desulfurase (Nfs1p) activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DDR48 |
YMR173W |
DNA damage-responsive protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MET10 |
YFR030W |
Subunit alpha of assimilatory sulfite reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRS1 |
YNL247W |
Cysteinyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CUE3 |
YGL110C |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPT1 |
YGR123C |
Protein serine/threonine phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PPX1 |
YHR201C |
Exopolyphosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCD14 |
YJL125C |
Subunit of tRNA (1-methyladenosine) methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OLE1 |
YGL055W |
Delta(9) fatty acid desaturase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG33 |
YLR356W |
Mitochondrial mitophagy-specific protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUZ1 |
YNL155W |
Protein with a role in the ubiquitin-proteasome pathway |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| ADE12 |
YNL220W |
Adenylosuccinate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ERV2 |
YPR037C |
Flavin-linked sulfhydryl oxidase localized to the ER lumen |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAG2 |
YOL025W |
Protein that negatively regulates the SCF E3-ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPT1 |
YOR209C |
Nicotinate phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ALD4 |
YOR374W |
Mitochondrial aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CYC7 |
YEL039C |
Cytochrome c isoform 2, expressed under hypoxic conditions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| OXP1 |
YKL215C |
5-oxoprolinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FCY1 |
YPR062W |
Cytosine deaminase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PHO13 |
YDL236W |
Conserved phosphatase acting as a metabolite repair enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARO3 |
YDR035W |
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL33B |
YOR234C |
Ribosomal 60S subunit protein L33B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL33B |
YOR234C |
Ribosomal 60S subunit protein L33B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GVP36 |
YIL041W |
BAR domain protein that localizes to early and late Golgi vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IDI1 |
YPL117C |
Isopentenyl diphosphate:dimethylallyl diphosphate isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL36A |
YMR194W |
Ribosomal 60S subunit protein L36A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL34A |
YER056C-A |
Ribosomal 60S subunit protein L34A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABP140 |
YOR239W |
AdoMet-dependent tRNA methyltransferase and actin binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DFM1 |
YDR411C |
Endoplasmic reticulum (ER) localized protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PDX3 |
YBR035C |
Pyridoxine (pyridoxamine) phosphate oxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NMT1 |
YLR195C |
N-myristoyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNR2 |
YKL064W |
Vacuolar membrane protein required for magnesium homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIS5 |
YIL116W |
Histidinol-phosphate aminotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RNH70 |
YGR276C |
3'-5' exoribonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GAS3 |
YMR215W |
Putative 1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET2 |
YNL277W |
L-homoserine-O-acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYT1 |
YOR065W |
Cytochrome c1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD57 |
YDR004W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KTR1 |
YOR099W |
Alpha-1,2-mannosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GSC2 |
YGR032W |
Catalytic subunit of 1,3-beta-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| OSH6 |
YKR003W |
Oxysterol-binding phosphatidylserine transferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIB1 |
YBL033C |
GTP cyclohydrolase II |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ASP1 |
YDR321W |
Cytosolic L-asparaginase, involved in asparagine catabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRX18 |
YBR056W |
Putative glycoside hydrolase of the mitochondrial intermembrane space |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HEM2 |
YGL040C |
Aminolevulinate dehydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS2 |
YBR038W |
Chitin synthase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PCS60 |
YBR222C |
Oxalyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NPR1 |
YNL183C |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KIP3 |
YGL216W |
Kinesin-related antiparallel sliding motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RBS1 |
YDL189W |
Protein involved in assembly of the RNA Pol III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NIT3 |
YLR351C |
Nit protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RMR1 |
YGL250W |
Protein required for meiotic recombination and gene conversion |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NRE1 |
YIR035C |
Putative cytoplasmic short-chain dehydrogenase/reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IRC24 |
YIR036C |
Putative benzil reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CHO1 |
YER026C |
Phosphatidylserine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DAK1 |
YML070W |
Dihydroxyacetone kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DAN4 |
YJR151C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BSC4 |
YNL269W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MET13 |
YGL125W |
Major isozyme of methylenetetrahydrofolate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIS1 |
YER055C |
ATP phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL33A |
YPL143W |
Ribosomal 60S subunit protein L33A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MYG1 |
YER156C |
Protein involved in mitochondrial function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CBP4 |
YGR174C |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ21 |
YBR230W-A |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSC2 |
YGR244C |
Beta subunit of succinyl-CoA ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FSH3 |
YOR280C |
Putative serine hydrolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MSC1 |
YML128C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LOG1 |
YJL055W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GLD1 |
YPR109W |
Component of Dsc E3 ligase complex in Golgi and endosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCH4 |
YOL119C |
Protein with similarity to mammalian monocarboxylate permeases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIC10 |
YCL057C-A |
Conserved component of the MICOS complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSS2 |
YDL107W |
Peripherally bound inner membrane protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ENB1 |
YOL158C |
Ferric enterobactin transmembrane transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCV2 |
YMR189W |
P subunit of the mitochondrial glycine decarboxylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NMA111 |
YNL123W |
Serine protease and general molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RBK1 |
YCR036W |
Ribokinase, phosphorylates ribose to ribose-5-phosphate |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIC2 |
YER053C |
Mitochondrial copper and phosphate carrier |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIB2 |
YOL066C |
Bifunctional DRAP deaminase tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTS2 |
YDR371W |
Putative chitinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IRC21 |
YMR073C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX11 |
YPL041C |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD61 |
YDR014W |
Subunit of a complex that inhibits sister chromatid cohesion |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LDB16 |
YCL005W |
Protein involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HXT13 |
YEL069C |
Putative transmembrane polyol transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCH1 |
YMR034C |
Negative regulator of cytosolic calcium homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |