GEnome-wide tool for Multi-scale Modeling
data Extraction and Representation
for Saccharomyces cerevisiae

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.

Standard name	Systematic name	Name description	Type	#Experiments	#Methods	#Publications	Evidence
PDE2	YOR360C	High-affinity cyclic AMP phosphodiesterase	genetic	8	3	5	Synthetic Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Rescue, Phenotypic Suppression
IRA1	YBR140C	GTPase-activating protein	genetic	7	4	6	Dosage Rescue, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SLT2	YHR030C	Serine/threonine MAP kinase	genetic	7	2	6	Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWI4	YER111C	DNA binding component of the SBF complex (Swi4p-Swi6p)	genetic	7	1	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAS2	YNL098C	GTP-binding protein	genetic	6	3	6	Dosage Lethality, Synthetic Rescue, Synthetic Rescue, Positive Genetic, Positive Genetic, Positive Genetic
SNF1	YDR477W	AMP-activated S/T protein kinase	genetic	6	1	5	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ROM2	YLR371W	Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p	genetic	6	3	4	Dosage Rescue, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
CDC25	YLR310C	Membrane bound guanine nucleotide exchange factor	genetic	6	2	4	Synthetic Rescue, Positive Genetic, Positive Genetic, Positive Genetic, Synthetic Rescue, Synthetic Rescue
BCK1	YJL095W	MAPKKK acting in the protein kinase C signaling pathway	genetic	6	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HOG1	YLR113W	Mitogen-activated protein kinase involved in osmoregulation	genetic	6	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GPB1	YOR371C	Multistep regulator of cAMP-PKA signaling	physical	6	4	2	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Biochemical Activity, Reconstituted Complex
SWC5	YBR231C	Component of the SWR1 complex	genetic	5	2	5	Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PAT1	YCR077C	Deadenylation-dependent mRNA-decapping factor	genetic	5	2	4	Positive Genetic, Negative Genetic, Negative Genetic, Positive Genetic, Negative Genetic
CRD1	YDL142C	Cardiolipin synthase	genetic	5	2	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality
CDC73	YLR418C	Component of the Paf1p complex	genetic	5	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YKE2	YLR200W	Subunit of the heterohexameric Gim/prefoldin protein complex	genetic	5	1	4	Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
BRE5	YNR051C	Ubiquitin protease cofactor	genetic	5	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EAF7	YNL136W	Subunit of the NuA4 histone acetyltransferase complex	genetic	5	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GPT2	YKR067W	Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase	genetic	5	2	3	Negative Genetic, Negative Genetic, Positive Genetic, Negative Genetic, Negative Genetic
ARO1	YDR127W	Pentafunctional arom protein	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IDH2	YOR136W	Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YMC2	YBR104W	Putative mitochondrial inner membrane transporter	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MGR1	YCL044C	Subunit of the mitochondrial (mt) i-AAA protease supercomplex	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PTH1	YHR189W	One of two mitochondrially-localized peptidyl-tRNA hydrolases	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MGR3	YMR115W	Subunit of the mitochondrial (mt) i-AAA protease supercomplex	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MIC60	YKR016W	Component of the MICOS complex	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RCF1	YML030W	Cytochrome c oxidase subunit	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PNT1	YOR266W	Mitochondrial integral inner membrane protein	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IDH1	YNL037C	Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase	genetic	5	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PPH3	YDR075W	Catalytic subunit of protein phosphatase PP4 complex	genetic	4	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IRC21	YMR073C	Protein of unknown function	genetic	4	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TSA1	YML028W	Thioredoxin peroxidase	genetic	4	3	3	Negative Genetic, Negative Genetic, Synthetic Rescue, Phenotypic Suppression
HTZ1	YOL012C	Histone variant H2AZ	genetic	4	2	3	Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SKI3	YPR189W	Ski complex component and TPR protein	genetic	4	2	3	Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LSM1	YJL124C	Lsm (Like Sm) protein	genetic	4	2	3	Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic
DST1	YGL043W	General transcription elongation factor TFIIS	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HAP2	YGL237C	Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEM1	YDR363W-A	19S proteasome regulatory particle lid subcomplex component	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IST3	YIR005W	Component of the U2 snRNP	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VID22	YLR373C	G-quadruplex (G4) DNA binding protein	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBP6	YFR010W	Ubiquitin-specific protease	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VIP1	YLR410W	Bifunctional inositol pyrophosphate kinase and phosphatase	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS27	YNR006W	Endosomal protein that forms a complex with Hse1p	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MDH3	YDL078C	Peroxisomal malate dehydrogenase	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SNF4	YGL115W	Activating gamma subunit of the AMP-activated Snf1p kinase complex	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SAC1	YKL212W	Phosphatidylinositol phosphate phosphatase	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YDJ1	YNL064C	Type I HSP40 co-chaperone	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MED1	YPR070W	Subunit of the RNA polymerase II mediator complex	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SET2	YJL168C	Histone methyltransferase with a role in transcriptional elongation	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CIK1	YMR198W	Kinesin-associated protein	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HXK2	YGL253W	Hexokinase isoenzyme 2	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERV29	YGR284C	Protein localized to COPII-coated vesicles	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DEG1	YFL001W	tRNA:pseudouridine synthase	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TFS1	YLR178C	Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p)	physical	4	3	2	Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western
EFT2	YDR385W	Elongation factor 2 (EF-2), also encoded by EFT1	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FAR7	YFR008W	Protein involved in recovery from pheromone-induced cell cycle arrest	genetic	4	1	2	Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
OMS1	YDR316W	Protein integral to the mitochondrial membrane	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MTO1	YGL236C	Mitochondrial protein	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SRB2	YHR041C	Subunit of the RNA polymerase II mediator complex	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PTK1	YKL198C	Putative serine/threonine protein kinase	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MSS1	YMR023C	Mitochondrial protein	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
KAR3	YPR141C	Minus-end-directed microtubule motor	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CSM1	YCR086W	Nucleolar protein that mediates homolog segregation during meiosis I	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GPB2	YAL056W	Multistep regulator of cAMP-PKA signaling	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ATP10	YLR393W	Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ARO7	YPR060C	Chorismate mutase	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
AVL9	YLR114C	Conserved protein involved in exocytic transport from the Golgi	genetic	4	1	2	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAS1	YOR101W	GTPase involved in G-protein signaling in adenylate cyclase activation	genetic	3	3	3	Dosage Lethality, Synthetic Rescue, Positive Genetic
SSE1	YPL106C	ATPase component of heat shock protein Hsp90 chaperone complex	genetic	3	2	3	Dosage Rescue, Negative Genetic, Negative Genetic
RTT103	YDR289C	Protein involved in transcription termination by RNA polymerase II	genetic	3	2	3	Negative Genetic, Negative Genetic, Positive Genetic
LRP1	YHR081W	Nuclear exosome-associated nucleic acid binding protein	genetic	3	2	3	Positive Genetic, Negative Genetic, Negative Genetic
TPS1	YBR126C	Synthase subunit of trehalose-6-P synthase/phosphatase complex	genetic	3	2	3	Negative Genetic, Negative Genetic, Synthetic Rescue
DOA1	YKL213C	WD-repeat protein involved in ubiquitin-mediated protein degradation	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
IES5	YER092W	Non-essential INO80 chromatin remodeling complex subunit	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
UBP3	YER151C	Ubiquitin-specific protease that cleaves Ub-protein fusions	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
NUT1	YGL151W	Component of the RNA polymerase II mediator complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
MSC1	YML128C	Protein of unknown function	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
RAD23	YEL037C	Protein with ubiquitin-like N terminus	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
SPT8	YLR055C	Subunit of the SAGA transcriptional regulatory complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
VPS72	YDR485C	Htz1p-binding component of the SWR1 complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
SAP30	YMR263W	Component of Rpd3L histone deacetylase complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
RIP1	YEL024W	Ubiquinol-cytochrome-c reductase	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
SHY1	YGR112W	Mitochondrial inner membrane protein required for complex IV assembly	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
NHP10	YDL002C	Non-essential INO80 chromatin remodeling complex subunit	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
RPO41	YFL036W	Mitochondrial RNA polymerase	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
MIC19	YFR011C	Component of the MICOS complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
MGA2	YIR033W	ER membrane protein involved in regulation of OLE1 transcription	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
SUR7	YML052W	Plasma membrane protein, component of eisosomes	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
PSY2	YNL201C	Subunit of protein phosphatase PP4 complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
BUD13	YGL174W	Subunit of the RES complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
ICP55	YER078C	Mitochondrial aminopeptidase	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
HMG2	YLR450W	HMG-CoA reductase	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
ALD6	YPL061W	Cytosolic aldehyde dehydrogenase	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
ATP12	YJL180C	Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
COX8	YLR395C	Subunit VIII of cytochrome c oxidase (Complex IV)	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
FMC1	YIL098C	Mitochondrial matrix protein	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
SPC24	YMR117C	Component of the kinetochore-associated Ndc80 complex	genetic	3	2	2	Synthetic Growth Defect, Negative Genetic, Negative Genetic
MED8	YBR193C	Subunit of the RNA polymerase II mediator complex	genetic	3	2	2	Synthetic Growth Defect, Negative Genetic, Negative Genetic
SGS1	YMR190C	RecQ family nucleolar DNA helicase	genetic	3	2	2	Negative Genetic, Negative Genetic, Positive Genetic
DBF4	YDR052C	Regulatory subunit of Cdc7p-Dbf4p kinase complex	genetic	3	2	2	Synthetic Growth Defect, Negative Genetic, Negative Genetic
ELO3	YLR372W	Elongase	genetic	3	2	2	Positive Genetic, Negative Genetic, Negative Genetic
HRQ1	YDR291W	3'-5' DNA helicase of the conserved RecQ family	genetic	3	2	2	Negative Genetic, Negative Genetic, Positive Genetic
HAP5	YOR358W	Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
BEM1	YBR200W	Protein containing SH3-domains	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
ASC1	YMR116C	G-protein beta subunit and guanine dissociation inhibitor for Gpa2p	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
BEM2	YER155C	Rho GTPase activating protein (RhoGAP)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CDC11	YJR076C	Component of the septin ring that is required for cytokinesis	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CDC23	YHR166C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
GCN1	YGL195W	Positive regulator of the Gcn2p kinase activity	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
GIM3	YNL153C	Subunit of the heterohexameric cochaperone prefoldin complex	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
GIM5	YML094W	Subunit of the heterohexameric cochaperone prefoldin complex	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
BRE2	YLR015W	Subunit of COMPASS (Set1C) complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
GAS1	YMR307W	Beta-1,3-glucanosyltransferase required for cell wall assembly	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
ACO1	YLR304C	Aconitase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
VPS71	YML041C	Nucleosome-binding component of the SWR1 complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
JJJ1	YNL227C	Co-chaperone that stimulates the ATPase activity of Ssa1p	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
MDM10	YAL010C	Subunit of both the ERMES and the SAM complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SCO2	YBR024W	Protein anchored to mitochondrial inner membrane	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RPN4	YDL020C	Transcription factor that stimulates expression of proteasome genes	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RMD1	YDL001W	Cytoplasmic protein required for sporulation	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
LCB2	YDR062W	Component of serine palmitoyltransferase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PAA1	YDR071C	Polyamine acetyltransferase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SLU7	YDR088C	RNA splicing factor	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PEX5	YDR244W	Peroxisomal membrane signal receptor for peroxisomal matrix proteins	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RPP2B	YDR382W	Ribosomal protein P2 beta	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
PPM1	YDR435C	Carboxyl methyltransferase	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
QCR6	YFR033C	Subunit 6 of the ubiquinol cytochrome-c reductase complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RIM8	YGL045W	Protein involved in proteolytic activation of Rim101p	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
PEX31	YGR004W	Peroxisomal integral membrane protein	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PRE9	YGR135W	Alpha 3 subunit of the 20S proteasome	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
QCR9	YGR183C	Subunit 9 of ubiquinol cytochrome-c reductase (Complex III)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SMI1	YGR229C	Protein involved in the regulation of cell wall synthesis	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
SPO12	YHR152W	Nucleolar protein of unknown function	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MHP1	YJL042W	Microtubule-associated protein involved in microtubule organization	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
NFU1	YKL040C	Protein involved in Fe-S cluster transfer to mitochondrial clients	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
NUP133	YKR082W	Subunit of Nup84p subcomplex of nuclear pore complex (NPC)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
TGL4	YKR089C	Multifunctional lipase/hydrolase/phospholipase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
YHC1	YLR298C	Component of the U1 snRNP complex required for pre-mRNA splicing	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MRE11	YMR224C	Nuclease subunit of the MRX complex with Rad50p and Xrs2p	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PHO23	YNL097C	Component of the Rpd3L histone deacetylase complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
NPR3	YHL023C	Subunit of the Iml1p/SEACIT complex	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SOD2	YHR008C	Mitochondrial manganese superoxide dismutase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
TDA3	YHR009C	Putative oxidoreductase involved in late endosome to Golgi transport	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SMT1	YJL147C	Translational repressor of the mitochondrial ATP6/8 mRNA	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PEX13	YLR191W	Peroxisomal importomer complex component	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RSF1	YMR030W	Protein required for respiratory growth	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
LSM7	YNL147W	Lsm (Like Sm) protein	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
LCB4	YOR171C	Sphingoid long-chain base kinase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
RTC6	YPL183W-A	Protein involved in translation	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
TKL1	YPR074C	Transketolase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
MET16	YPR167C	3'-phosphoadenylsulfate reductase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
PRE4	YFR050C	Beta 7 subunit of the 20S proteasome	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
UPS1	YLR193C	Phosphatidic acid transfer protein	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
SUR1	YPL057C	Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
KIN28	YDL108W	Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
APP1	YNL094W	Phosphatidate phosphatase, converts phosphatidate to diacylglycerol	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CPR6	YLR216C	Peptidyl-prolyl cis-trans isomerase (cyclophilin)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
FAR3	YMR052W	Protein of unknown function	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
IPK1	YDR315C	Inositol 1,3,4,5,6-pentakisphosphate 2-kinase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
ARP6	YLR085C	Actin-related protein that binds nucleosomes	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
ERF2	YLR246W	Subunit of a palmitoyltransferase	genetic	3	1	2	Positive Genetic, Positive Genetic, Positive Genetic
ATP18	YML081C-A	Subunit of the mitochondrial F1F0 ATP synthase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
BTS1	YPL069C	Geranylgeranyl diphosphate synthase (GGPPS)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
DPH5	YLR172C	Methyltransferase required for synthesis of diphthamide	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
ARO2	YGL148W	Bifunctional chorismate synthase and flavin reductase	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
EMI1	YDR512C	Non-essential protein of unknown function	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
CMC1	YKL137W	Copper-binding protein of the mitochondrial intermembrane space	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
COA6	YMR244C-A	Protein involved in cytochrome c oxidase (Complex IV) assembly	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
ATP23	YNR020C	Putative metalloprotease of the mitochondrial inner membrane	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
ICE2	YIL090W	Integral ER membrane protein with type-III transmembrane domains	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
BCY1	YIL033C	Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA)	physical	3	3	1	Reconstituted Complex, Protein-peptide, Affinity Capture-Western
TAF5	YBR198C	Subunit (90 kDa) of TFIID and SAGA complexes	genetic	3	2	1	Positive Genetic, Negative Genetic, Negative Genetic
CDC42	YLR229C	Small rho-like GTPase	genetic	2	2	2	Negative Genetic, Positive Genetic
CTK1	YKL139W	Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I)	genetic	2	2	2	Synthetic Lethality, Negative Genetic
EDE1	YBL047C	Scaffold protein involved in the formation of early endocytic sites	genetic	2	2	2	Negative Genetic, Phenotypic Enhancement
HSP82	YPL240C	Hsp90 chaperone	genetic	2	2	2	Synthetic Lethality, Positive Genetic
CDC13	YDL220C	Single stranded DNA-binding protein found at TG1-3 telomere G-tails	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
RAS2	YNL098C	GTP-binding protein	physical	2	2	2	Biochemical Activity, Reconstituted Complex
TPK2	YPL203W	cAMP-dependent protein kinase catalytic subunit	genetic	2	2	2	Synthetic Rescue, Synthetic Growth Defect
SCH9	YHR205W	AGC family protein kinase	genetic	2	2	2	Dosage Rescue, Synthetic Rescue
SSN8	YNL025C	Cyclin-like component of RNA polymerase II holoenzyme	genetic	2	2	2	Positive Genetic, Negative Genetic
RAD53	YPL153C	DNA damage response kinase	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
RVS167	YDR388W	Calmodulin-binding actin-associated protein	genetic	2	2	2	Negative Genetic, Positive Genetic
PDR11	YIL013C	ATP-binding cassette (ABC) transporter	genetic	2	2	2	Positive Genetic, Negative Genetic
TEL2	YGR099W	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	2	2	2	Positive Genetic, Negative Genetic
YPI1	YFR003C	Regulatory subunit of the type I protein phosphatase (PP1) Glc7p	genetic	2	2	2	Negative Genetic, Positive Genetic
RAD5	YLR032W	DNA helicase/Ubiquitin ligase	genetic	2	2	2	Negative Genetic, Dosage Lethality
CDC7	YDL017W	S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase)	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
BIM1	YER016W	Microtubule plus end-tracking protein	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
GLN3	YER040W	Transcriptional activator in nitrogen catabolite repression system	genetic	2	2	2	Negative Genetic, Positive Genetic
FLO1	YAR050W	Lectin-like protein involved in flocculation	genetic	2	2	2	Negative Genetic, Positive Genetic
DBP7	YKR024C	Putative ATP-dependent RNA helicase of the DEAD-box family	genetic	2	1	2	Negative Genetic, Negative Genetic
HGH1	YGR187C	Chaperone protein for translation factor eEF2	genetic	2	1	2	Negative Genetic, Negative Genetic
CEG1	YGL130W	Guanylyltransferase involved in mRNA 5' capping	genetic	2	1	2	Negative Genetic, Negative Genetic
COX5A	YNL052W	Subunit Va of cytochrome c oxidase	genetic	2	1	2	Negative Genetic, Negative Genetic
FAB1	YFR019W	1-phosphatidylinositol-3-phosphate 5-kinase	genetic	2	1	2	Positive Genetic, Positive Genetic
HRR25	YPL204W	Conserved casein kinase, monopolin subunit	genetic	2	1	2	Negative Genetic, Negative Genetic
IES1	YFL013C	Subunit of the INO80 chromatin remodeling complex	genetic	2	1	2	Negative Genetic, Negative Genetic
GCN20	YFR009W	Positive regulator of the Gcn2p kinase activity	genetic	2	1	2	Negative Genetic, Negative Genetic
FAR8	YMR029C	Protein involved in recovery from arrest in response to pheromone	genetic	2	1	2	Positive Genetic, Positive Genetic
RIM15	YFL033C	Protein kinase involved in cell proliferation in response to nutrients	genetic	2	1	2	Negative Genetic, Negative Genetic
PHB1	YGR132C	Subunit of the prohibitin complex (Phb1p-Phb2p)	genetic	2	1	2	Negative Genetic, Negative Genetic
WHI2	YOR043W	Negative regulator of TORC1 in response to limiting leucine	genetic	2	1	2	Negative Genetic, Negative Genetic
SSD1	YDR293C	Translational repressor	genetic	2	1	2	Negative Genetic, Negative Genetic
SOD1	YJR104C	Cytosolic copper-zinc superoxide dismutase	genetic	2	1	2	Negative Genetic, Negative Genetic
SPT3	YDR392W	Subunit of the SAGA and SAGA-like transcriptional regulatory complexes	genetic	2	1	2	Negative Genetic, Negative Genetic
SWR1	YDR334W	Swi2/Snf2-related ATPase	genetic	2	1	2	Negative Genetic, Negative Genetic
MCK1	YNL307C	Dual-specificity ser/thr and tyrosine protein kinase	genetic	2	1	2	Negative Genetic, Negative Genetic
RAD52	YML032C	Protein involved in homologous recombination	genetic	2	1	2	Negative Genetic, Negative Genetic
SPF1	YEL031W	P-type ATPase, ion transporter of the ER membrane	genetic	2	1	2	Negative Genetic, Negative Genetic
UBP8	YMR223W	Ubiquitin-specific protease component of the SAGA acetylation complex	genetic	2	1	2	Positive Genetic, Positive Genetic
SHP1	YBL058W	UBX domain-containing substrate adaptor for Cdc48p	genetic	2	1	2	Negative Genetic, Negative Genetic
PAU10	YDR542W	Protein of unknown function	genetic	2	1	2	Positive Genetic, Positive Genetic
SEC27	YGL137W	Essential beta'-coat protein of the COPI coatomer	genetic	2	1	2	Negative Genetic, Negative Genetic
MMF1	YIL051C	Mitochondrial protein required for transamination of isoleucine	genetic	2	1	2	Negative Genetic, Negative Genetic
MET30	YIL046W	F-box protein containing five copies of the WD40 motif	genetic	2	1	2	Negative Genetic, Negative Genetic
RSM7	YJR113C	Mitochondrial ribosomal protein of the small subunit	genetic	2	1	2	Negative Genetic, Negative Genetic
YCS4	YLR272C	Subunit of the condensin complex	genetic	2	1	2	Negative Genetic, Negative Genetic
LSM3	YLR438C-A	Lsm (Like Sm) protein	genetic	2	1	2	Negative Genetic, Negative Genetic
POB3	YML069W	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p)	genetic	2	1	2	Negative Genetic, Negative Genetic
RNA1	YMR235C	GTPase activating protein (GAP) for Gsp1p	genetic	2	1	2	Negative Genetic, Negative Genetic
SIN4	YNL236W	Subunit of the RNA polymerase II mediator complex	genetic	2	1	2	Negative Genetic, Negative Genetic
PEX22	YAL055W	Putative peroxisomal membrane protein	genetic	2	1	2	Negative Genetic, Negative Genetic
PIN4	YBL051C	Protein involved in G2/M phase progression and response to DNA damage	genetic	2	1	2	Negative Genetic, Negative Genetic
RXT2	YBR095C	Component of the histone deacetylase Rpd3L complex	genetic	2	1	2	Negative Genetic, Negative Genetic
PDB1	YBR221C	E1 beta subunit of the pyruvate dehydrogenase (PDH) complex	genetic	2	1	2	Positive Genetic, Positive Genetic
RPP1A	YDL081C	Ribosomal stalk protein P1 alpha	genetic	2	1	2	Negative Genetic, Negative Genetic
RXT3	YDL076C	Component of the Rpd3L histone deacetylase complex	genetic	2	1	2	Negative Genetic, Negative Genetic
PEX19	YDL065C	Chaperone and import receptor for newly-synthesized class I PMPs	genetic	2	1	2	Negative Genetic, Negative Genetic
SLM3	YDL033C	tRNA-specific 2-thiouridylase	genetic	2	1	2	Negative Genetic, Negative Genetic
MNN10	YDR245W	Subunit of a Golgi mannosyltransferase complex	genetic	2	1	2	Negative Genetic, Negative Genetic
PEX10	YDR265W	Peroxisomal membrane E3 ubiquitin ligase	genetic	2	1	2	Negative Genetic, Negative Genetic
LSM6	YDR378C	Lsm (Like Sm) protein	genetic	2	1	2	Negative Genetic, Negative Genetic
VPS60	YDR486C	Protein involved in late endosome to vacuole transport	genetic	2	1	2	Negative Genetic, Negative Genetic
MYG1	YER156C	Protein involved in mitochondrial function	genetic	2	1	2	Negative Genetic, Negative Genetic
YGL235W	YGL235W	Putative protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
KAP122	YGL016W	Karyopherin beta	genetic	2	1	2	Positive Genetic, Positive Genetic
PEX8	YGR077C	Intraperoxisomal organizer of the peroxisomal import machinery	genetic	2	1	2	Negative Genetic, Negative Genetic
MRP13	YGR084C	Mitochondrial ribosomal protein of the small subunit	genetic	2	1	2	Negative Genetic, Negative Genetic
PCP1	YGR101W	Mitochondrial serine protease	genetic	2	1	2	Negative Genetic, Negative Genetic
RPS27B	YHR021C	Protein component of the small (40S) ribosomal subunit	genetic	2	1	2	Negative Genetic, Negative Genetic
KSP1	YHR082C	Serine/threonine protein kinase	genetic	2	1	2	Negative Genetic, Negative Genetic
STB5	YHR178W	Transcription factor	genetic	2	1	2	Negative Genetic, Negative Genetic
POT1	YIL160C	3-ketoacyl-CoA thiolase with broad chain length specificity	genetic	2	1	2	Negative Genetic, Negative Genetic
RGI2	YIL057C	Protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
PEX2	YJL210W	RING-finger peroxin and E3 ubiquitin ligase	genetic	2	1	2	Negative Genetic, Negative Genetic
RPS21B	YJL136C	Protein component of the small (40S) ribosomal subunit	genetic	2	1	2	Negative Genetic, Negative Genetic
SNX4	YJL036W	Sorting nexin	genetic	2	1	2	Positive Genetic, Positive Genetic
MOG1	YJR074W	Conserved nuclear protein that interacts with GTP-Gsp1p	genetic	2	1	2	Positive Genetic, Positive Genetic
MRP49	YKL167C	Mitochondrial ribosomal protein of the large subunit	genetic	2	1	2	Negative Genetic, Negative Genetic
YKL069W	YKL069W	Methionine-R-sulfoxide reductase	genetic	2	1	2	Negative Genetic, Negative Genetic
PAN3	YKL025C	Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex	genetic	2	1	2	Negative Genetic, Negative Genetic
IRC25	YLR021W	Component of a heterodimeric Poc4p-Irc25p chaperone	genetic	2	1	2	Negative Genetic, Negative Genetic
SRN2	YLR119W	Component of the ESCRT-I complex	genetic	2	1	2	Negative Genetic, Negative Genetic
RPL38	YLR325C	Ribosomal 60S subunit protein L38	genetic	2	1	2	Positive Genetic, Positive Genetic
RPL26A	YLR344W	Ribosomal 60S subunit protein L26A	genetic	2	1	2	Positive Genetic, Positive Genetic
USA1	YML029W	Scaffold subunit of the Hrd1p ubiquitin ligase	genetic	2	1	2	Negative Genetic, Negative Genetic
PSP2	YML017W	Asn rich cytoplasmic protein that contains RGG motifs	genetic	2	1	2	Negative Genetic, Negative Genetic
SUB1	YMR039C	Transcriptional regulator	genetic	2	1	2	Negative Genetic, Negative Genetic
UBX4	YMR067C	UBX domain-containing protein that interacts with Cdc48p	genetic	2	1	2	Negative Genetic, Negative Genetic
MKS1	YNL076W	Pleiotropic negative transcriptional regulator	genetic	2	1	2	Negative Genetic, Negative Genetic
RNH201	YNL072W	Ribonuclease H2 catalytic subunit	genetic	2	1	2	Negative Genetic, Negative Genetic
LAT1	YNL071W	Dihydrolipoamide acetyltransferase component (E2) of the PDC	genetic	2	1	2	Positive Genetic, Positive Genetic
VAM3	YOR106W	Syntaxin-like vacuolar t-SNARE	genetic	2	1	2	Negative Genetic, Negative Genetic
SSP2	YOR242C	Sporulation specific protein that localizes to the spore wall	genetic	2	1	2	Negative Genetic, Negative Genetic
POC4	YPL144W	Component of a heterodimeric Poc4p-Irc25p chaperone	genetic	2	1	2	Negative Genetic, Negative Genetic
SPP1	YPL138C	Subunit of COMPASS (Set1C)	genetic	2	1	2	Negative Genetic, Negative Genetic
VPS30	YPL120W	Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II	genetic	2	1	2	Negative Genetic, Negative Genetic
RGL1	YPL066W	Regulator of Rho1p signaling, cofactor of Tus1p	genetic	2	1	2	Negative Genetic, Negative Genetic
NHP6A	YPR052C	High-mobility group (HMG) protein	genetic	2	1	2	Negative Genetic, Negative Genetic
RPT4	YOR259C	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	2	1	2	Negative Genetic, Negative Genetic
SNT309	YPR101W	Member of the NineTeen Complex (NTC)	genetic	2	1	2	Negative Genetic, Negative Genetic
PTC1	YDL006W	Type 2C protein phosphatase (PP2C)	genetic	2	1	2	Negative Genetic, Negative Genetic
YDL157C	YDL157C	Putative protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
LRS4	YDR439W	Nucleolar protein that forms a complex with Csm1p	genetic	2	1	2	Negative Genetic, Negative Genetic
PMA1	YGL008C	Plasma membrane P2-type H+-ATPase	genetic	2	1	2	Negative Genetic, Negative Genetic
PIB2	YGL023C	Phosphatidylinositol 3-phosphate binding protein	genetic	2	1	2	Positive Genetic, Positive Genetic
MDM34	YGL219C	Mitochondrial component of the ERMES complex	genetic	2	1	2	Negative Genetic, Negative Genetic
PHB2	YGR231C	Subunit of the prohibitin complex (Phb1p-Phb2p)	genetic	2	1	2	Negative Genetic, Negative Genetic
IRE1	YHR079C	Serine-threonine kinase and endoribonuclease	genetic	2	1	2	Positive Genetic, Positive Genetic
MRS1	YIR021W	Splicing protein	genetic	2	1	2	Negative Genetic, Negative Genetic
PET130	YJL023C	Protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
PBS2	YJL128C	MAP kinase kinase of the HOG signaling pathway	genetic	2	1	2	Negative Genetic, Negative Genetic
PAM17	YKR065C	Constituent of the TIM23 complex	genetic	2	1	2	Negative Genetic, Negative Genetic
TDA5	YLR426W	Putative protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
TIM23	YNR017W	Essential component of the TIM23 complex	genetic	2	1	2	Negative Genetic, Negative Genetic
RCF2	YNR018W	Cytochrome c oxidase subunit	genetic	2	1	2	Negative Genetic, Negative Genetic
NEW1	YPL226W	Translation termination and ribosome biogenesis factor	genetic	2	1	2	Negative Genetic, Negative Genetic
VPS4	YPR173C	AAA-ATPase involved in multivesicular body (MVB) protein sorting	genetic	2	1	2	Negative Genetic, Negative Genetic
TUB2	YFL037W	Beta-tubulin	genetic	2	1	2	Negative Genetic, Negative Genetic
MYO2	YOR326W	Type V myosin motor involved in actin-based transport of cargos	genetic	2	1	2	Negative Genetic, Negative Genetic
PTC2	YER089C	Type 2C protein phosphatase (PP2C)	genetic	2	1	2	Negative Genetic, Negative Genetic
QCR2	YPR191W	Subunit 2 of ubiquinol cytochrome-c reductase (Complex III)	genetic	2	1	2	Negative Genetic, Negative Genetic
GPP1	YIL053W	Constitutively expressed DL-glycerol-3-phosphate phosphatase	genetic	2	1	2	Negative Genetic, Negative Genetic
ESL2	YKR096W	hEST1A/B (SMG5/6)-like protein	genetic	2	1	2	Negative Genetic, Negative Genetic
DBF20	YPR111W	Ser/Thr kinase involved in late nuclear division	genetic	2	1	2	Negative Genetic, Negative Genetic
HIR2	YOR038C	Subunit of HIR nucleosome assembly complex	genetic	2	1	2	Negative Genetic, Negative Genetic
DBF2	YGR092W	Ser/Thr kinase involved in transcription and stress response	genetic	2	1	2	Negative Genetic, Negative Genetic
CBR1	YIL043C	Cytochrome b reductase and NADH-dependent reductase for Dph3p	genetic	2	1	2	Negative Genetic, Negative Genetic
GCR2	YNL199C	Transcriptional activator of genes involved in glycolysis	genetic	2	1	2	Negative Genetic, Negative Genetic
CDH1	YGL003C	Activator of anaphase-promoting complex/cyclosome (APC/C)	genetic	2	1	2	Negative Genetic, Negative Genetic
ATP5	YDR298C	Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase	genetic	2	1	2	Negative Genetic, Negative Genetic
DID4	YKL002W	Class E Vps protein of the ESCRT-III complex	genetic	2	1	2	Negative Genetic, Negative Genetic
CLN3	YAL040C	G1 cyclin involved in cell cycle progression	genetic	2	1	2	Negative Genetic, Negative Genetic
GZF3	YJL110C	GATA zinc finger protein	genetic	2	1	2	Negative Genetic, Negative Genetic
BAS1	YKR099W	Myb-related transcription factor	genetic	2	1	2	Negative Genetic, Negative Genetic
AIM18	YHR198C	Protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
GIM4	YEL003W	Subunit of the heterohexameric cochaperone prefoldin complex	genetic	2	1	2	Positive Genetic, Positive Genetic
BNR1	YIL159W	Formin	genetic	2	1	2	Negative Genetic, Negative Genetic
FBP1	YLR377C	Fructose-1,6-bisphosphatase	genetic	2	1	2	Negative Genetic, Negative Genetic
FIR1	YER032W	Protein involved in 3' mRNA processing	genetic	2	1	2	Negative Genetic, Negative Genetic
CLA4	YNL298W	Cdc42p-activated signal transducing kinase	genetic	2	1	2	Negative Genetic, Negative Genetic
CHS5	YLR330W	Component of the exomer complex	genetic	2	1	2	Synthetic Growth Defect, Synthetic Growth Defect
DID2	YKR035W-A	Class E protein of the vacuolar protein-sorting (Vps) pathway	genetic	2	1	2	Negative Genetic, Negative Genetic
ATG10	YLL042C	Conserved E2-like conjugating enzyme	genetic	2	1	2	Negative Genetic, Negative Genetic
ERV14	YGL054C	COPII-coated vesicle protein	genetic	2	1	2	Negative Genetic, Negative Genetic
CLB3	YDL155W	B-type cyclin involved in cell cycle progression	genetic	2	1	2	Negative Genetic, Negative Genetic
DUS3	YLR401C	Dihydrouridine synthase	genetic	2	1	2	Negative Genetic, Negative Genetic
ATP14	YLR295C	Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase	genetic	2	1	2	Negative Genetic, Negative Genetic
IMP21	YIL154C	Transcriptional activator involved in maintenance of ion homeostasis	genetic	2	1	2	Negative Genetic, Negative Genetic
COA4	YLR218C	Twin Cx(9)C protein involved in cytochrome c oxidase organization	genetic	2	1	2	Negative Genetic, Negative Genetic
CHS6	YJL099W	Member of the ChAPs (Chs5p-Arf1p-binding proteins) family	genetic	2	1	2	Synthetic Growth Defect, Synthetic Growth Defect
AIM11	YER093C-A	Protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
AAD4	YDL243C	Putative aryl-alcohol dehydrogenase	genetic	2	1	2	Negative Genetic, Negative Genetic
COS12	YGL263W	Endosomal protein involved in turnover of plasma membrane proteins	genetic	2	1	2	Negative Genetic, Negative Genetic
DAT1	YML113W	DNA binding protein that recognizes oligo(dA).oligo(dT) tracts	genetic	2	1	2	Negative Genetic, Negative Genetic
COX9	YDL067C	Subunit VIIa of cytochrome c oxidase (Complex IV)	genetic	2	1	2	Negative Genetic, Negative Genetic
CYT2	YKL087C	Cytochrome c1 heme lyase	genetic	2	1	2	Negative Genetic, Negative Genetic
CPR8	YNR028W	Peptidyl-prolyl cis-trans isomerase (cyclophilin)	genetic	2	1	2	Negative Genetic, Negative Genetic
CBT1	YKL208W	Protein involved in 5' RNA end processing	genetic	2	1	2	Negative Genetic, Negative Genetic
HPM1	YIL110W	AdoMet-dependent methyltransferase	genetic	2	1	2	Positive Genetic, Positive Genetic
ACT1	YFL039C	Actin, structural protein in cytoskeleton	genetic	2	1	1	Positive Genetic, Positive Genetic
EPL1	YFL024C	Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
FRS1	YLR060W	Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase	genetic	2	1	1	Negative Genetic, Negative Genetic
CSE2	YNR010W	Subunit of the RNA polymerase II mediator complex	genetic	2	1	1	Negative Genetic, Negative Genetic
GEP3	YOR205C	Protein required for mitochondrial ribosome small subunit biogenesis	genetic	2	1	1	Negative Genetic, Negative Genetic
HMO1	YDR174W	Chromatin associated high mobility group (HMG) family member	genetic	2	1	1	Negative Genetic, Negative Genetic
DNM1	YLL001W	Dynamin-related GTPase involved in mitochondrial organization	genetic	2	1	1	Negative Genetic, Negative Genetic
VAM6	YDL077C	Guanine nucleotide exchange factor for the GTPase Gtr1p	genetic	2	1	1	Positive Genetic, Positive Genetic
RPA14	YDR156W	RNA polymerase I subunit A14	genetic	2	1	1	Negative Genetic, Negative Genetic
VAM7	YGL212W	Vacuolar SNARE protein	genetic	2	1	1	Negative Genetic, Negative Genetic
YJR120W	YJR120W	Protein of unknown function	genetic	2	1	1	Negative Genetic, Negative Genetic
YKR104W	YKR104W	Putative transporter of the MRP subfamily	genetic	2	1	1	Negative Genetic, Negative Genetic
YPT6	YLR262C	Rab family GTPase	genetic	2	1	1	Negative Genetic, Negative Genetic
RIM20	YOR275C	Protein involved in proteolytic activation of Rim101p	genetic	2	1	1	Positive Genetic, Positive Genetic
SOV1	YMR066W	Mitochondrial protein of unknown function	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
JSN1	YJR091C	Member of the Puf family of RNA-binding proteins	genetic	2	1	1	Positive Genetic, Positive Genetic
STE24	YJR117W	Highly conserved zinc metalloprotease	genetic	2	1	1	Negative Genetic, Negative Genetic
MGM101	YJR144W	Protein with a role in mitochondrial DNA recombinational repair	genetic	2	1	1	Negative Genetic, Negative Genetic
VPH2	YKL119C	Integral membrane protein required for V-ATPase function	genetic	2	1	1	Negative Genetic, Negative Genetic
OCT1	YKL134C	Mitochondrial intermediate peptidase	genetic	2	1	1	Negative Genetic, Negative Genetic
MSS51	YLR203C	Specific translational activator for the mitochondrial COX1 mRNA	genetic	2	1	1	Negative Genetic, Negative Genetic
ORM2	YLR350W	Protein that mediates sphingolipid homeostasis	genetic	2	1	1	Negative Genetic, Negative Genetic
SPC2	YML055W	Subunit of signal peptidase complex	genetic	2	1	1	Negative Genetic, Negative Genetic
PGA3	YML125C	Putative cytochrome b5 reductase, localized to the plasma membrane	genetic	2	1	1	Negative Genetic, Negative Genetic
YTA12	YMR089C	Mitochondrial inner membrane m-AAA protease component	genetic	2	1	1	Negative Genetic, Negative Genetic
PPA2	YMR267W	Mitochondrial inorganic pyrophosphatase	genetic	2	1	1	Negative Genetic, Negative Genetic
SCS7	YMR272C	Sphingolipid alpha-hydroxylase	genetic	2	1	1	Negative Genetic, Negative Genetic
POR1	YNL055C	Mitochondrial porin (voltage-dependent anion channel)	genetic	2	1	1	Negative Genetic, Negative Genetic
PSD1	YNL169C	Phosphatidylserine decarboxylase of the mitochondrial inner membrane	genetic	2	1	1	Negative Genetic, Negative Genetic
TLG2	YOL018C	Syntaxin-like t-SNARE	genetic	2	1	1	Negative Genetic, Negative Genetic
MIP1	YOR330C	Mitochondrial DNA polymerase gamma	genetic	2	1	1	Negative Genetic, Negative Genetic
MSC6	YOR354C	Multicopy suppressor of HER2 involved in mitochondrial translation	genetic	2	1	1	Negative Genetic, Negative Genetic
MFM1	YPL060W	Mitochondrial inner membrane magnesium transporter	genetic	2	1	1	Negative Genetic, Negative Genetic
NIP100	YPL174C	Large subunit of the dynactin complex	genetic	2	1	1	Negative Genetic, Negative Genetic
VMA11	YPL234C	Vacuolar ATPase V0 domain subunit c'	genetic	2	1	1	Negative Genetic, Negative Genetic
SEC22	YLR268W	R-SNARE protein	genetic	2	1	1	Positive Genetic, Positive Genetic
STM1	YLR150W	Protein required for optimal translation under nutrient stress	genetic	2	1	1	Positive Genetic, Positive Genetic
NSE4	YDL105W	Component of the SMC5-SMC6 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
SUP35	YDR172W	Translation termination factor eRF3	genetic	2	1	1	Negative Genetic, Negative Genetic
RSP5	YER125W	NEDD4 family E3 ubiquitin ligase	genetic	2	1	1	Negative Genetic, Negative Genetic
RPT6	YGL048C	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
NUP145	YGL092W	Essential protein with distinct roles in two nuclear pore subcomplexes	genetic	2	1	1	Negative Genetic, Negative Genetic
SPC105	YGL093W	Subunit of a kinetochore-microtubule binding complex	genetic	2	1	1	Negative Genetic, Negative Genetic
NUP57	YGR119C	FG-nucleoporin component of central core of the nuclear pore complex	genetic	2	1	1	Negative Genetic, Negative Genetic
RPT1	YKL145W	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	2	1	1	Negative Genetic, Negative Genetic
MGE1	YOR232W	Mitochondrial matrix cochaperone	genetic	2	1	1	Negative Genetic, Negative Genetic
ARF1	YDL192W	ADP-ribosylation factor	genetic	2	1	1	Negative Genetic, Negative Genetic
FYV10	YIL097W	Subunit of GID complex	genetic	2	1	1	Negative Genetic, Negative Genetic
GYP6	YJL044C	GTPase-activating protein (GAP) for yeast Rab family member Ypt6p	genetic	2	1	1	Negative Genetic, Negative Genetic
HOM2	YDR158W	Aspartic beta semi-aldehyde dehydrogenase	genetic	2	1	1	Negative Genetic, Negative Genetic
ESS1	YJR017C	Peptidylprolyl-cis/trans-isomerase (PPIase)	genetic	2	1	1	Negative Genetic, Negative Genetic
GNA1	YFL017C	Glucosamine-6-phosphate acetyltransferase	genetic	2	1	1	Negative Genetic, Negative Genetic
ATC1	YDR184C	Nuclear protein	genetic	2	1	1	Negative Genetic, Negative Genetic
FRA1	YLL029W	Protein involved in negative regulation of iron regulon transcription	genetic	2	1	1	Positive Genetic, Positive Genetic
GEP5	YLR091W	Protein of unknown function	genetic	2	1	1	Negative Genetic, Negative Genetic
ARV1	YLR242C	Cortical ER protein	genetic	2	1	1	Negative Genetic, Negative Genetic
CYC1	YJR048W	Cytochrome c, isoform 1	genetic	2	1	1	Negative Genetic, Negative Genetic
CYT1	YOR065W	Cytochrome c1	genetic	2	1	1	Negative Genetic, Negative Genetic
COQ2	YNR041C	Para hydroxybenzoate polyprenyl transferase	genetic	2	1	1	Negative Genetic, Negative Genetic
CYC2	YOR037W	Mitochondrial peripheral inner membrane protein	genetic	2	1	1	Negative Genetic, Negative Genetic
ERS1	YCR075C	Protein involved in cystine transport	genetic	2	1	1	Negative Genetic, Negative Genetic
HER2	YMR293C	Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex	genetic	2	1	1	Negative Genetic, Negative Genetic
CDC1	YDR182W	Putative mannose-ethanolamine phosphate phosphodiesterase	genetic	2	1	1	Negative Genetic, Negative Genetic
IMP2	YMR035W	Catalytic subunit of mitochondrial inner membrane peptidase complex	genetic	2	1	1	Negative Genetic, Negative Genetic
APQ12	YIL040W	Nuclear envelope/ER integral membrane protein	genetic	2	1	1	Positive Genetic, Positive Genetic
RFX1	YLR176C	Major transcriptional repressor of DNA-damage-regulated genes	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MED2	YDL005C	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
RGR1	YLR071C	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YAP1	YML007W	Basic leucine zipper (bZIP) transcription factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
TFC7	YOR110W	RNA pol III transcription initiation factor complex (TFIIIC) subunit	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
HSF1	YGL073W	Trimeric heat shock transcription factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SUA7	YPR086W	Transcription factor TFIIB	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SPT3	YDR392W	Subunit of the SAGA and SAGA-like transcriptional regulatory complexes	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SPT7	YBR081C	Subunit of the SAGA transcriptional regulatory complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SPT6	YGR116W	Nucleosome remodeling protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CTR9	YOL145C	Component of the Paf1p complex involved in transcription elongation	genetic	1	1	1	Positive Genetic
AME1	YBR211C	Essential kinetochore protein associated with microtubules and SPBs	genetic	1	1	1	Negative Genetic
DSN1	YIR010W	Essential component of the outer kinetochore MIND complex	genetic	1	1	1	Negative Genetic
GWT1	YJL091C	Protein involved in the inositol acylation of GlcN-PI	genetic	1	1	1	Positive Genetic
ARP4	YJL081C	Nuclear actin-related protein involved in chromatin remodeling	genetic	1	1	1	Negative Genetic
HAS1	YMR290C	ATP-dependent RNA helicase	genetic	1	1	1	Negative Genetic
AXL2	YIL140W	Integral plasma membrane protein	genetic	1	1	1	Negative Genetic
BRE1	YDL074C	E3 ubiquitin ligase	genetic	1	1	1	Negative Genetic
BMH1	YER177W	14-3-3 protein, major isoform	genetic	1	1	1	Positive Genetic
DED1	YOR204W	ATP-dependent DEAD-box RNA helicase with strand-annealing activity	genetic	1	1	1	Negative Genetic
IML1	YJR138W	GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex	genetic	1	1	1	Negative Genetic
CDC48	YDL126C	AAA ATPase with protein-unfoldase activity	genetic	1	1	1	Negative Genetic
AAH1	YNL141W	Adenine deaminase (adenine aminohydrolase)	genetic	1	1	1	Negative Genetic
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	physical	1	1	1	Affinity Capture-RNA
CDC39	YCR093W	Subunit of the CCR4-NOT1 core complex	genetic	1	1	1	Negative Genetic
BMS1	YPL217C	GTPase required for ribosomal subunit synthesis and rRNA processing	genetic	1	1	1	Negative Genetic
AOS1	YPR180W	Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p	genetic	1	1	1	Negative Genetic
APC1	YNL172W	Largest subunit of the Anaphase-Promoting Complex/Cyclosome	genetic	1	1	1	Negative Genetic
ARC18	YLR370C	Subunit of the ARP2/3 complex	genetic	1	1	1	Positive Genetic
BDF1	YLR399C	BET family transcriptional regulator	genetic	1	1	1	Negative Genetic
BET3	YKR068C	Core component of transport protein particle (TRAPP) complexes I-III	genetic	1	1	1	Negative Genetic
BET2	YPR176C	Beta subunit of Type II geranylgeranyltransferase	genetic	1	1	1	Negative Genetic
ASC1	YMR116C	G-protein beta subunit and guanine dissociation inhibitor for Gpa2p	physical	1	1	1	Affinity Capture-MS
CAP1	YKL007W	Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p)	genetic	1	1	1	Negative Genetic
CDC28	YBR160W	Cyclin-dependent kinase (CDK) catalytic subunit	genetic	1	1	1	Negative Genetic
CDC10	YCR002C	Component of the septin ring, required for cytokinesis	genetic	1	1	1	Positive Genetic
ERG26	YGL001C	C-3 sterol dehydrogenase	genetic	1	1	1	Negative Genetic
COX6	YHR051W	Subunit VI of cytochrome c oxidase (Complex IV)	genetic	1	1	1	Negative Genetic
CTF18	YMR078C	Subunit of a complex with Ctf8p	genetic	1	1	1	Positive Genetic
CYS4	YGR155W	Cystathionine beta-synthase	genetic	1	1	1	Negative Genetic
ELP2	YGR200C	Subunit of Elongator complex	genetic	1	1	1	Positive Genetic
GCN2	YDR283C	Protein kinase	genetic	1	1	1	Negative Genetic
HAT1	YPL001W	Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex	genetic	1	1	1	Positive Genetic
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	physical	1	1	1	Affinity Capture-RNA
AEP1	YMR064W	Protein required for expression of the mitochondrial OLI1 gene	genetic	1	1	1	Negative Genetic
AEP2	YMR282C	Mitochondrial protein	genetic	1	1	1	Negative Genetic
IML3	YBR107C	Outer kinetochore protein and component of the Ctf19 complex	genetic	1	1	1	Negative Genetic
ENO2	YHR174W	Enolase II, a phosphopyruvate hydratase	genetic	1	1	1	Negative Genetic
FBA1	YKL060C	Fructose 1,6-bisphosphate aldolase	physical	1	1	1	Affinity Capture-MS
FBA1	YKL060C	Fructose 1,6-bisphosphate aldolase	genetic	1	1	1	Negative Genetic
HRR25	YPL204W	Conserved casein kinase, monopolin subunit	physical	1	1	1	Affinity Capture-MS
CCM1	YGR150C	Mitochondrial 15S rRNA-binding protein	genetic	1	1	1	Negative Genetic
ATG3	YNR007C	E2-like enzyme	genetic	1	1	1	Negative Genetic
GIN4	YDR507C	Protein kinase involved in bud growth and assembly of the septin ring	genetic	1	1	1	Negative Genetic
ARP8	YOR141C	Nuclear actin-related protein involved in chromatin remodeling	genetic	1	1	1	Negative Genetic
INO80	YGL150C	Nucleosome spacing factor	genetic	1	1	1	Negative Genetic
AHA1	YDR214W	Co-chaperone that binds Hsp82p and activates its ATPase activity	genetic	1	1	1	Negative Genetic
DOA4	YDR069C	Ubiquitin hydrolase	genetic	1	1	1	Negative Genetic
HTA1	YDR225W	Histone H2A	genetic	1	1	1	Positive Genetic
DAM1	YGR113W	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	1	1	1	Negative Genetic
BUD21	YOR078W	Component of small ribosomal subunit (SSU) processosome	genetic	1	1	1	Negative Genetic
ANP1	YEL036C	Subunit of the alpha-1,6 mannosyltransferase complex	genetic	1	1	1	Negative Genetic
BSP1	YPR171W	Adapter that links synaptojanins to the cortical actin cytoskeleton	genetic	1	1	1	Positive Genetic
HFI1	YPL254W	Adaptor protein required for structural integrity of the SAGA complex	genetic	1	1	1	Negative Genetic
CCT6	YDR188W	Subunit of the cytosolic chaperonin Cct ring complex	genetic	1	1	1	Negative Genetic
BET5	YML077W	Core component of transport protein particle (TRAPP) complexes I-III	genetic	1	1	1	Positive Genetic
FDH1	YOR388C	NAD(+)-dependent formate dehydrogenase	genetic	1	1	1	Negative Genetic
DRS2	YAL026C	Trans-golgi network aminophospholipid translocase (flippase)	genetic	1	1	1	Positive Genetic
BDH2	YAL061W	Putative medium-chain alcohol dehydrogenase with similarity to BDH1	genetic	1	1	1	Negative Genetic
FES1	YBR101C	Hsp70 (Ssa1p) nucleotide exchange factor	genetic	1	1	1	Negative Genetic
GET3	YDL100C	Guanine nucleotide exchange factor for Gpa1p	genetic	1	1	1	Negative Genetic
FAR11	YNL127W	Protein involved in recovery from cell cycle arrest	genetic	1	1	1	Positive Genetic
ATP2	YJR121W	Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase	physical	1	1	1	Affinity Capture-MS
GPH1	YPR160W	Glycogen phosphorylase required for the mobilization of glycogen	genetic	1	1	1	Positive Genetic
AKL1	YBR059C	Ser/Thr protein kinase	genetic	1	1	1	Positive Genetic
MMS2	YGL087C	Ubiquitin-conjugating enzyme variant	physical	1	1	1	Affinity Capture-MS
RIM11	YMR139W	Protein kinase	physical	1	1	1	Affinity Capture-MS
RIM11	YMR139W	Protein kinase	genetic	1	1	1	Negative Genetic
NAB2	YGL122C	Nuclear polyadenylated RNA-binding protein	physical	1	1	1	Affinity Capture-RNA
TPK1	YJL164C	cAMP-dependent protein kinase catalytic subunit	physical	1	1	1	Biochemical Activity
TPK1	YJL164C	cAMP-dependent protein kinase catalytic subunit	genetic	1	1	1	Synthetic Rescue
TPK2	YPL203W	cAMP-dependent protein kinase catalytic subunit	physical	1	1	1	Biochemical Activity
TPK3	YKL166C	cAMP-dependent protein kinase catalytic subunit	physical	1	1	1	Biochemical Activity
TPK3	YKL166C	cAMP-dependent protein kinase catalytic subunit	genetic	1	1	1	Positive Genetic
SSA1	YAL005C	ATPase involved in protein folding and NLS-directed nuclear transport	physical	1	1	1	Affinity Capture-MS
PGK1	YCR012W	3-phosphoglycerate kinase	physical	1	1	1	Affinity Capture-MS
RIM15	YFL033C	Protein kinase involved in cell proliferation in response to nutrients	physical	1	1	1	Affinity Capture-MS
PSA1	YDL055C	GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase)	physical	1	1	1	Affinity Capture-MS
RNQ1	YCL028W	[PIN(+)] prion	physical	1	1	1	Affinity Capture-MS
PHB1	YGR132C	Subunit of the prohibitin complex (Phb1p-Phb2p)	physical	1	1	1	Affinity Capture-MS
SSE1	YPL106C	ATPase component of heat shock protein Hsp90 chaperone complex	physical	1	1	1	Affinity Capture-MS
KAR2	YJL034W	ATPase involved in protein import into the ER	physical	1	1	1	Affinity Capture-MS
KAR2	YJL034W	ATPase involved in protein import into the ER	genetic	1	1	1	Negative Genetic
VMA1	YDL185W	Subunit A of the V1 peripheral membrane domain of V-ATPase	physical	1	1	1	Affinity Capture-MS
URA1	YKL216W	Dihydroorotate dehydrogenase	physical	1	1	1	Affinity Capture-MS
UBP3	YER151C	Ubiquitin-specific protease that cleaves Ub-protein fusions	physical	1	1	1	Affinity Capture-Western
UBI4	YLL039C	Ubiquitin	physical	1	1	1	Affinity Capture-Western
SRP54	YPR088C	Signal recognition particle (SRP) subunit (homolog of mammalian SRP54)	physical	1	1	1	Co-purification
VAM6	YDL077C	Guanine nucleotide exchange factor for the GTPase Gtr1p	physical	1	1	1	Affinity Capture-MS
PUF3	YLL013C	Protein of the mitochondrial outer surface	physical	1	1	1	Affinity Capture-RNA
SSC1	YJR045C	Hsp70 family ATPase	physical	1	1	1	Affinity Capture-MS
TOM1	YDR457W	E3 ubiquitin ligase of the hect-domain class	physical	1	1	1	Affinity Capture-MS
RIO1	YOR119C	Serine kinase involved in cell cycle regulation and rDNA integrity	physical	1	1	1	Two-hybrid
TOM22	YNL131W	Component of the TOM (Translocase of Outer Membrane) complex	physical	1	1	1	Affinity Capture-MS
TOM22	YNL131W	Component of the TOM (Translocase of Outer Membrane) complex	genetic	1	1	1	Negative Genetic
RSC6	YCR052W	Component of the RSC chromatin remodeling complex	genetic	1	1	1	Negative Genetic
NUP84	YDL116W	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
TFG2	YGR005C	TFIIF (Transcription Factor II) middle subunit	genetic	1	1	1	Negative Genetic
MAD2	YJL030W	Component of the spindle-assembly checkpoint complex	genetic	1	1	1	Negative Genetic
VPS70	YJR126C	Protein of unknown function involved in vacuolar protein sorting	genetic	1	1	1	Negative Genetic
YAF9	YNL107W	Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes	genetic	1	1	1	Negative Genetic
SPN1	YPR133C	Protein involved in RNA polymerase II transcription	genetic	1	1	1	Negative Genetic
MED11	YMR112C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
PGD1	YGL025C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
RPC25	YKL144C	RNA polymerase III subunit C25	genetic	1	1	1	Negative Genetic
SDC1	YDR469W	Subunit of the COMPASS (Set1C) complex	genetic	1	1	1	Negative Genetic
PTA1	YAL043C	Subunit of holo-CPF	genetic	1	1	1	Negative Genetic
SWI6	YLR182W	Transcription cofactor	genetic	1	1	1	Negative Genetic
RPC11	YDR045C	RNA polymerase III subunit C11	genetic	1	1	1	Negative Genetic
JHD2	YJR119C	JmjC domain family histone demethylase	genetic	1	1	1	Negative Genetic
MED4	YOR174W	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
PFD1	YJL179W	Subunit of heterohexameric prefoldin	genetic	1	1	1	Positive Genetic
SGO1	YOR073W	Component of the spindle checkpoint	genetic	1	1	1	Positive Genetic
RAD6	YGL058W	Ubiquitin-conjugating enzyme (E2)	genetic	1	1	1	Positive Genetic
REI1	YBR267W	Cytoplasmic pre-60S factor	genetic	1	1	1	Positive Genetic
SUS1	YBR111W-A	Global transcriptional regulator, component of SAGA, TREX-2 complexes	genetic	1	1	1	Positive Genetic
SPT21	YMR179W	Protein with a role in transcriptional silencing	genetic	1	1	1	Positive Genetic
TAF14	YPL129W	Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes	genetic	1	1	1	Positive Genetic
SWD3	YBR175W	Essential subunit of the COMPASS (Set1C) complex	genetic	1	1	1	Positive Genetic
MON1	YGL124C	Subunit of a heterodimeric guanine nucleotide exchange factor (GEF)	genetic	1	1	1	Positive Genetic
TAF12	YDR145W	Subunit (61/68 kDa) of TFIID and SAGA complexes	genetic	1	1	1	Positive Genetic
RPA43	YOR340C	RNA polymerase I subunit A43	genetic	1	1	1	Positive Genetic
SLA1	YBL007C	Cytoskeletal protein binding protein	genetic	1	1	1	Positive Genetic
RPN13	YLR421C	Subunit of the 19S regulatory particle of the 26S proteasome lid	genetic	1	1	1	Positive Genetic
SRP40	YKR092C	Nucleolar serine-rich protein	genetic	1	1	1	Positive Genetic
SNF3	YDL194W	Plasma membrane low glucose sensor, regulates glucose transport	genetic	1	1	1	Synthetic Rescue
TSC11	YER093C	Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p)	genetic	1	1	1	Synthetic Growth Defect
POP4	YBR257W	Subunit of both RNase MRP and nuclear RNase P	genetic	1	1	1	Negative Genetic
VMA9	YCL005W-A	Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex	genetic	1	1	1	Negative Genetic
RPC53	YDL150W	RNA polymerase III subunit C53	genetic	1	1	1	Negative Genetic
YRB1	YDR002W	Ran GTPase binding protein	genetic	1	1	1	Negative Genetic
SDD1	YEL057C	Protein of unknown function	genetic	1	1	1	Negative Genetic
VMA3	YEL027W	Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase	genetic	1	1	1	Positive Genetic
SEC3	YER008C	Subunit of the exocyst complex	genetic	1	1	1	Negative Genetic
RNA15	YGL044C	Component of the cleavage and polyadenylation factor I (CF I)	genetic	1	1	1	Negative Genetic
SWI3	YJL176C	Subunit of the SWI/SNF chromatin remodeling complex	genetic	1	1	1	Negative Genetic
VMA6	YLR447C	Subunit d of the V0 integral membrane domain of V-ATPase	genetic	1	1	1	Negative Genetic
TAP42	YMR028W	Essential protein involved in the TOR signaling pathway	genetic	1	1	1	Negative Genetic
URE2	YNL229C	Nitrogen catabolite repression transcriptional regulator	genetic	1	1	1	Negative Genetic
MUM2	YBR057C	Protein essential for meiotic DNA replication and sporulation	genetic	1	1	1	Negative Genetic
MSI1	YBR195C	Subunit of chromatin assembly factor I (CAF-1)	genetic	1	1	1	Negative Genetic
STE50	YCL032W	Adaptor protein for various signaling pathways	genetic	1	1	1	Negative Genetic
TIM13	YGR181W	Mitochondrial intermembrane space protein	genetic	1	1	1	Negative Genetic
TNA1	YGR260W	High affinity nicotinic acid plasma membrane permease	genetic	1	1	1	Negative Genetic
RIM101	YHL027W	Cys2His2 zinc-finger transcriptional repressor	genetic	1	1	1	Positive Genetic
NVJ1	YHR195W	Nuclear envelope protein	genetic	1	1	1	Positive Genetic
RCI37	YIL077C	Protein that associates with the large mitoribosomal subunit	genetic	1	1	1	Negative Genetic
ISY1	YJR050W	Member of the NineTeen Complex (NTC)	genetic	1	1	1	Negative Genetic
MDM35	YKL053C-A	Mitochondrial intermembrane space protein	genetic	1	1	1	Positive Genetic
MEH1	YKR007W	Subunit of the EGO/GSE complex	genetic	1	1	1	Positive Genetic
SND2	YLR065C	Protein involved in SRP-independent targeting of substrates to the ER	genetic	1	1	1	Positive Genetic
VRP1	YLR337C	Verprolin, proline-rich actin-associated protein	genetic	1	1	1	Positive Genetic
RPS1A	YLR441C	Ribosomal protein of the small (40S) subunit	genetic	1	1	1	Negative Genetic
ZDS2	YML109W	Protein with a role in regulating Swe1p-dependent polarized growth	genetic	1	1	1	Negative Genetic
MRPL39	YML009C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
PKR1	YMR123W	V-ATPase assembly factor	genetic	1	1	1	Negative Genetic
SSO2	YMR183C	Plasma membrane t-SNARE	genetic	1	1	1	Positive Genetic
PFK2	YMR205C	Beta subunit of heterooctameric phosphofructokinase	genetic	1	1	1	Positive Genetic
VHS3	YOR054C	Negative regulatory subunit of protein phosphatase 1 Ppz1p	genetic	1	1	1	Negative Genetic
RPS30B	YOR182C	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
YPL068C	YPL068C	Protein of unknown function	genetic	1	1	1	Negative Genetic
SRO7	YPR032W	Effector of Rab GTPase Sec4p	genetic	1	1	1	Positive Genetic
SIN3	YOL004W	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	genetic	1	1	1	Negative Genetic
PPT2	YPL148C	Phosphopantetheine:protein transferase (PPTase)	genetic	1	1	1	Negative Genetic
PDE1	YGL248W	Low-affinity cyclic AMP phosphodiesterase	genetic	1	1	1	Synthetic Rescue
VMA21	YGR105W	Integral membrane protein required for V-ATPase function	genetic	1	1	1	Synthetic Growth Defect
NAB3	YPL190C	RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p)	genetic	1	1	1	Synthetic Growth Defect
PIM1	YBL022C	ATP-dependent Lon protease	genetic	1	1	1	Negative Genetic
URA7	YBL039C	Major CTP synthase isozyme (see also URA8)	genetic	1	1	1	Negative Genetic
RTG3	YBL103C	bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways	genetic	1	1	1	Negative Genetic
UBC4	YBR082C	Ubiquitin-conjugating enzyme (E2)	genetic	1	1	1	Negative Genetic
MIS1	YBR084W	Mitochondrial C1-tetrahydrofolate synthase	genetic	1	1	1	Negative Genetic
YSA1	YBR111C	Nudix hydrolase family member with ADP-ribose pyrophosphatase activity	genetic	1	1	1	Negative Genetic
VMA2	YBR127C	Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase	genetic	1	1	1	Negative Genetic
OPY1	YBR129C	Protein of unknown function	genetic	1	1	1	Negative Genetic
SEC66	YBR171W	Non-essential subunit of Sec63 complex	genetic	1	1	1	Negative Genetic
NOP1	YDL014W	Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus	genetic	1	1	1	Negative Genetic
NRG1	YDR043C	Transcriptional repressor	genetic	1	1	1	Positive Genetic
RRG1	YDR065W	Protein of unknown function	genetic	1	1	1	Negative Genetic
MSS116	YDR194C	Mitochondrial transcription elongation factor	genetic	1	1	1	Positive Genetic
VPS64	YDR200C	Protein required for cytoplasm to vacuole targeting of proteins	genetic	1	1	1	Positive Genetic
SWA2	YDR320C	Auxilin-like protein involved in vesicular transport	genetic	1	1	1	Negative Genetic
PEP7	YDR323C	Adaptor protein involved in vesicle-mediated vacuolar protein sorting	genetic	1	1	1	Negative Genetic
SHE9	YDR393W	Protein required for normal mitochondrial morphology	genetic	1	1	1	Negative Genetic
VPS52	YDR484W	Component of the GARP (Golgi-associated retrograde protein) complex	genetic	1	1	1	Negative Genetic
NRD1	YNL251C	RNA-binding subunit of Nrd1 complex	genetic	1	1	1	Synthetic Growth Defect
VAC8	YEL013W	Vacuole-specific Myo2p receptor	genetic	1	1	1	Positive Genetic
ISC1	YER019W	Inositol phosphosphingolipid phospholipase C	genetic	1	1	1	Positive Genetic
YCK3	YER123W	Palmitoylated vacuolar membrane-localized casein kinase I isoform	genetic	1	1	1	Negative Genetic
SCL1	YGL011C	Alpha 1 subunit of the 20S proteasome	genetic	1	1	1	Negative Genetic
PMR1	YGL167C	High affinity Ca2+/Mn2+ P-type ATPase	genetic	1	1	1	Negative Genetic
VRG4	YGL225W	Golgi GDP-mannose transporter	genetic	1	1	1	Negative Genetic
PET54	YGR222W	Mitochondrial inner membrane protein	genetic	1	1	1	Negative Genetic
VMA22	YHR060W	Protein that is required for vacuolar H+-ATPase (V-ATPase) function	genetic	1	1	1	Negative Genetic
SOL3	YHR163W	6-phosphogluconolactonase	genetic	1	1	1	Negative Genetic
MDM31	YHR194W	Mitochondrial protein that may have a role in phospholipid metabolism	genetic	1	1	1	Negative Genetic
KGD1	YIL125W	Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex	genetic	1	1	1	Positive Genetic
OM45	YIL136W	Mitochondrial outer membrane protein of unknown function	genetic	1	1	1	Negative Genetic
RPS4A	YJR145C	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
SDH3	YKL141W	Subunit of succinate dehydrogenase and of TIM22 translocase	genetic	1	1	1	Negative Genetic
PCK1	YKR097W	Phosphoenolpyruvate carboxykinase	genetic	1	1	1	Negative Genetic
SEC61	YLR378C	Conserved ER protein translocation channel	genetic	1	1	1	Negative Genetic
YPT7	YML001W	Rab family GTPase	genetic	1	1	1	Positive Genetic
TUB3	YML124C	Alpha-tubulin	genetic	1	1	1	Negative Genetic
SAM37	YMR060C	Component of the Sorting and Assembly Machinery (SAM) complex	genetic	1	1	1	Negative Genetic
PRE5	YMR314W	Alpha 6 subunit of the 20S proteasome	genetic	1	1	1	Negative Genetic
MSK1	YNL073W	Mitochondrial lysine-tRNA synthetase	genetic	1	1	1	Negative Genetic
TPM1	YNL079C	Major isoform of tropomyosin	genetic	1	1	1	Negative Genetic
TOM70	YNL121C	Component of the TOM (translocase of outer membrane) complex	genetic	1	1	1	Negative Genetic
YNL146W	YNL146W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
RTT106	YNL206C	Histone chaperone	genetic	1	1	1	Negative Genetic
SEC2	YNL272C	Guanyl-nucleotide exchange factor for the small G-protein Sec4p	genetic	1	1	1	Negative Genetic
MDM12	YOL009C	Mitochondrial outer membrane protein, ERMES complex subunit	genetic	1	1	1	Negative Genetic
SGT2	YOR007C	Glutamine-rich cytoplasmic cochaperone	genetic	1	1	1	Negative Genetic
RGS2	YOR107W	Negative regulator of glucose-induced cAMP signaling	genetic	1	1	1	Negative Genetic
RTT10	YPL183C	WD40 domain-containing protein involved in endosomal recycling	genetic	1	1	1	Negative Genetic
RLF2	YPR018W	Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1)	genetic	1	1	1	Negative Genetic
MSF1	YPR047W	Mitochondrial phenylalanyl-tRNA synthetase	genetic	1	1	1	Negative Genetic
PRE2	YPR103W	Beta 5 subunit of the 20S proteasome	genetic	1	1	1	Negative Genetic
TOM5	YPR133W-A	Component of the TOM (translocase of outer membrane) complex	genetic	1	1	1	Negative Genetic
REG1	YDR028C	Regulatory subunit of type 1 protein phosphatase Glc7p	genetic	1	1	1	Synthetic Rescue
YKU70	YMR284W	Subunit of the telomeric Ku complex (Yku70p-Yku80p)	genetic	1	1	1	Negative Genetic
YOR1	YGR281W	Plasma membrane ATP-binding cassette (ABC) transporter	genetic	1	1	1	Negative Genetic
RTT107	YHR154W	BRCA1 C-terminal domain protein needed for recovery from DNA damage	genetic	1	1	1	Negative Genetic
SLX4	YLR135W	Endonuclease involved in processing DNA	genetic	1	1	1	Negative Genetic
UGP1	YKL035W	UDP-glucose pyrophosphorylase (UGPase)	genetic	1	1	1	Phenotypic Suppression
KOG1	YHR186C	Subunit of TORC1	genetic	1	1	1	Positive Genetic
REA1	YLR106C	Huge dynein-related AAA-type ATPase (midasin)	genetic	1	1	1	Positive Genetic
RAP1	YNL216W	Essential DNA-binding transcription regulator that binds many loci	genetic	1	1	1	Positive Genetic
MRD1	YPR112C	Essential conserved small ribosomal subunit (40s) synthesis factor	genetic	1	1	1	Positive Genetic
STU1	YBL034C	Microtubule plus-end-tracking non-motor protein	genetic	1	1	1	Positive Genetic
ORC2	YBR060C	Subunit of the origin recognition complex (ORC)	genetic	1	1	1	Positive Genetic
RPB7	YDR404C	RNA polymerase II subunit B16	genetic	1	1	1	Positive Genetic
SEC4	YFL005W	Rab family GTPase	genetic	1	1	1	Positive Genetic
PAM18	YLR008C	Subunit of the import motor (PAM complex)	genetic	1	1	1	Positive Genetic
ORC1	YML065W	Largest subunit of the origin recognition complex	genetic	1	1	1	Positive Genetic
UTP15	YMR093W	Nucleolar protein	genetic	1	1	1	Positive Genetic
RRP5	YMR229C	RNA binding protein involved in synthesis of 18S and 5.8S rRNAs	genetic	1	1	1	Positive Genetic
NOP2	YNL061W	rRNA m5C methyltransferase	genetic	1	1	1	Positive Genetic
SEC62	YPL094C	Essential subunit of Sec63 complex	genetic	1	1	1	Positive Genetic
RER1	YCL001W	Protein involved in retention of membrane proteins	genetic	1	1	1	Positive Genetic
STP22	YCL008C	Component of the ESCRT-I complex	genetic	1	1	1	Positive Genetic
RAM1	YDL090C	Beta subunit of the CAAX farnesyltransferase (FTase)	genetic	1	1	1	Positive Genetic
VPS54	YDR027C	Component of the GARP (Golgi-associated retrograde protein) complex	genetic	1	1	1	Positive Genetic
KGD2	YDR148C	Dihydrolipoyl transsuccinylase	genetic	1	1	1	Positive Genetic
RPL12B	YDR418W	Ribosomal 60S subunit protein L12B	genetic	1	1	1	Positive Genetic
YEA6	YEL006W	Mitochondrial NAD+ transporter	genetic	1	1	1	Positive Genetic
LPD1	YFL018C	Dihydrolipoamide dehydrogenase	genetic	1	1	1	Positive Genetic
KEL2	YGR238C	Protein that negatively regulates mitotic exit	genetic	1	1	1	Positive Genetic
OCA5	YHL029C	Cytoplasmic protein required for replication of Brome mosaic virus	genetic	1	1	1	Positive Genetic
SFB3	YHR098C	Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat	genetic	1	1	1	Positive Genetic
NCE101	YJL205C	Protein of unknown function	genetic	1	1	1	Positive Genetic
RIM21	YNL294C	pH sensor molecule, component of the RIM101 pathway	genetic	1	1	1	Positive Genetic
NPL4	YBR170C	Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase	genetic	1	1	1	Positive Genetic
RRP8	YDR083W	Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase	genetic	1	1	1	Positive Genetic
VTC4	YJL012C	Vacuolar membrane polyphosphate polymerase	genetic	1	1	1	Positive Genetic
VPS35	YJL154C	Endosomal subunit of membrane-associated retromer complex	genetic	1	1	1	Positive Genetic
TEF4	YKL081W	Gamma subunit of translational elongation factor eEF1B	genetic	1	1	1	Positive Genetic
RAD27	YKL113C	5' to 3' exonuclease, 5' flap endonuclease	genetic	1	1	1	Positive Genetic
VPS51	YKR020W	Component of the GARP (Golgi-associated retrograde protein) complex	genetic	1	1	1	Positive Genetic
UBR2	YLR024C	Cytoplasmic ubiquitin-protein ligase (E3)	genetic	1	1	1	Positive Genetic
YLR278C	YLR278C	Zinc-cluster protein	genetic	1	1	1	Positive Genetic
VPS9	YML097C	Guanine nucleotide exchange factor (GEF) and ubiquitin receptor	genetic	1	1	1	Positive Genetic
PMS1	YNL082W	ATP-binding protein required for mismatch repair	genetic	1	1	1	Positive Genetic
RPN5	YDL147W	Subunit of the CSN and 26S proteasome lid complexes	genetic	1	1	1	Negative Genetic
TIM22	YDL217C	Essential core component of mitochondrial TIM22 complex	genetic	1	1	1	Negative Genetic
UBC1	YDR177W	Ubiquitin-conjugating enzyme	genetic	1	1	1	Negative Genetic
SRB7	YDR308C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
YRA1	YDR381W	Nuclear polyadenylated RNA-binding protein	genetic	1	1	1	Negative Genetic
PMI40	YER003C	Mannose-6-phosphate isomerase	genetic	1	1	1	Negative Genetic
VHT1	YGR065C	High-affinity plasma membrane H+-biotin (vitamin H) symporter	genetic	1	1	1	Negative Genetic
PTI1	YGR156W	Essential component of CPF (cleavage and polyadenylation factor)	genetic	1	1	1	Negative Genetic
PUP2	YGR253C	Alpha 5 subunit of the 20S proteasome	genetic	1	1	1	Negative Genetic
MED6	YHR058C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
LSM8	YJR022W	Lsm (Like Sm) protein	genetic	1	1	1	Negative Genetic
STU2	YLR045C	Microtubule polymerase of the XMAP215/Dis1 family	genetic	1	1	1	Negative Genetic
SFH1	YLR321C	Component of the RSC chromatin remodeling complex	genetic	1	1	1	Negative Genetic
RPN8	YOR261C	Essential non-ATPase regulatory subunit of the 26S proteasome	genetic	1	1	1	Negative Genetic
NOP4	YPL043W	Nucleolar protein	genetic	1	1	1	Negative Genetic
SPC29	YPL124W	Inner plaque spindle pole body (SPB) component	genetic	1	1	1	Negative Genetic
NOP53	YPL146C	Nucleolar protein	genetic	1	1	1	Negative Genetic
PRP46	YPL151C	Member of the NineTeen Complex (NTC)	genetic	1	1	1	Negative Genetic
MCD1	YDL003W	Essential alpha-kleisin subunit of the cohesin complex	genetic	1	1	1	Negative Genetic
RPN6	YDL097C	Essential, non-ATPase regulatory subunit of the 26S proteasome lid	genetic	1	1	1	Negative Genetic
MAK21	YDR060W	Constituent of 66S pre-ribosomal particles	genetic	1	1	1	Negative Genetic
NSE3	YDR288W	Component of the SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
YCG1	YDR325W	Subunit of the condensin complex	genetic	1	1	1	Negative Genetic
SYF1	YDR416W	Member of the NineTeen Complex (NTC)	genetic	1	1	1	Negative Genetic
PUP3	YER094C	Beta 3 subunit of the 20S proteasome	genetic	1	1	1	Negative Genetic
NBP35	YGL091C	Essential cytoplasmic iron-sulfur cluster binding protein	genetic	1	1	1	Negative Genetic
SKI6	YGR195W	Exosome non-catalytic core component	genetic	1	1	1	Negative Genetic
MAS2	YHR024C	Alpha subunit of the mitochondrial processing protease (MPP)	genetic	1	1	1	Negative Genetic
RRP4	YHR069C	Exosome non-catalytic core component	genetic	1	1	1	Negative Genetic
MOB1	YIL106W	Component of the mitotic exit network	genetic	1	1	1	Negative Genetic
NUP159	YIL115C	FG-nucleoporin component of central core of the nuclear pore complex	genetic	1	1	1	Negative Genetic
NDC80	YIL144W	Component of the kinetochore-associated Ndc80 complex	genetic	1	1	1	Negative Genetic
SSL1	YLR005W	Subunit of the core form of RNA polymerase transcription factor TFIIH	genetic	1	1	1	Negative Genetic
NSE1	YLR007W	Component of the SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
RGR1	YLR071C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
SMC4	YLR086W	Subunit of the condensin complex	genetic	1	1	1	Negative Genetic
KAP95	YLR347C	Karyopherin beta	genetic	1	1	1	Negative Genetic
RSC9	YML127W	Component of the RSC chromatin remodeling complex	genetic	1	1	1	Negative Genetic
VTI1	YMR197C	Protein involved in cis-Golgi membrane traffic	genetic	1	1	1	Negative Genetic
LST8	YNL006W	Protein required for the transport of Gap1p	genetic	1	1	1	Negative Genetic
SEC63	YOR254C	Essential subunit of Sec63 complex	genetic	1	1	1	Negative Genetic
PRE10	YOR362C	Alpha 7 subunit of the 20S proteasome	genetic	1	1	1	Negative Genetic
RET3	YPL010W	Zeta subunit of the coatomer complex (COPI)	genetic	1	1	1	Negative Genetic
TIM50	YPL063W	Essential component of the TIM23 complex	genetic	1	1	1	Negative Genetic
TBF1	YPL128C	Telobox-containing general regulatory factor	genetic	1	1	1	Negative Genetic
NSL1	YPL233W	Essential component of the MIND kinetochore complex	genetic	1	1	1	Negative Genetic
SGV1	YPR161C	Cyclin (Bur2p)-dependent protein kinase	genetic	1	1	1	Negative Genetic
NUT2	YPR168W	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
RDH54	YBR073W	DNA-dependent ATPase	genetic	1	1	1	Negative Genetic
PHO5	YBR093C	Repressible acid phosphatase	genetic	1	1	1	Negative Genetic
SMP1	YBR182C	MADS-box transcription factor involved in osmotic stress response	genetic	1	1	1	Negative Genetic
ISW1	YBR245C	ATPase subunit of imitation-switch (ISWI) class chromatin remodelers	genetic	1	1	1	Negative Genetic
MRPL27	YBR282W	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
SPS22	YCL048W	Protein of unknown function	genetic	1	1	1	Negative Genetic
MRPL32	YCR003W	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
RPS14A	YCR031C	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
SNT1	YCR033W	Set3C histone deacetylase scaffold	genetic	1	1	1	Negative Genetic
MTF2	YDL044C	Mitochondrial protein that interacts with mitochondrial RNA polymerase	genetic	1	1	1	Negative Genetic
MRP10	YDL045W-A	Mitochondrial ribosomal protein of the small subunit	genetic	1	1	1	Negative Genetic
RPL4B	YDR012W	Ribosomal 60S subunit protein L4B	genetic	1	1	1	Negative Genetic
PST2	YDR032C	FMN-dependent NAD(P)H:quinone oxidoreductase	genetic	1	1	1	Negative Genetic
TFB5	YDR079C-A	Component of RNA polymerase II general transcription factor TFIIH	genetic	1	1	1	Negative Genetic
MRX14	YDR115W	Putative mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
MRPL1	YDR116C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
YDR131C	YDR131C	F-box protein subunit of SCF ubiquitin ligase complex	genetic	1	1	1	Negative Genetic
SND1	YDR186C	Protein involved in SRP-independent targeting of substrates to the ER	genetic	1	1	1	Negative Genetic
REF2	YDR195W	RNA-binding protein	genetic	1	1	1	Negative Genetic
YDR248C	YDR248C	Putative gluconokinase	genetic	1	1	1	Negative Genetic
MRX10	YDR282C	Mitochondrial inner membrane protein of unknown function	genetic	1	1	1	Negative Genetic
SIP1	YDR422C	One of three alternate beta-subunits of the Snf1p kinase complex	genetic	1	1	1	Negative Genetic
RPS17B	YDR447C	Ribosomal protein 51 (rp51) of the small (40s) subunit	genetic	1	1	1	Negative Genetic
NPR2	YEL062W	Subunit of the Iml1p/SEACIT complex	genetic	1	1	1	Negative Genetic
MRH4	YGL064C	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family	genetic	1	1	1	Negative Genetic
PAN2	YGL094C	Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex	genetic	1	1	1	Negative Genetic
RMD9	YGL107C	Mitochondrial protein that controls mitochondrial gene expression	genetic	1	1	1	Negative Genetic
KIP3	YGL216W	Kinesin-related antiparallel sliding motor protein	genetic	1	1	1	Negative Genetic
TAN1	YGL232W	Putative tRNA acetyltransferase	genetic	1	1	1	Negative Genetic
MCY1	YGR012W	Putative cysteine synthase	genetic	1	1	1	Negative Genetic
TIM21	YGR033C	Nonessential component of the TIM23 complex	genetic	1	1	1	Negative Genetic
RSC1	YGR056W	Component of the RSC chromatin remodeling complex	genetic	1	1	1	Negative Genetic
SPR3	YGR059W	Sporulation-specific homolog of the CDC3/10/11/12 family of genes	genetic	1	1	1	Negative Genetic
YCH1	YGR203W	Phosphatase with sequence similarity to Mih1p	genetic	1	1	1	Negative Genetic
RSM27	YGR215W	Mitochondrial ribosomal protein of the small subunit	genetic	1	1	1	Negative Genetic
MRPL9	YGR220C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
MAL11	YGR289C	High-affinity maltose transporter (alpha-glucoside transporter)	genetic	1	1	1	Negative Genetic
MRPL6	YHR147C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
PRP8	YHR165C	Component of U4/U6-U5 snRNP complex	genetic	1	1	1	Negative Genetic
MTG2	YHR168W	Putative GTPase	genetic	1	1	1	Negative Genetic
PPX1	YHR201C	Exopolyphosphatase	genetic	1	1	1	Negative Genetic
SYG1	YIL047C	Plasma membrane protein of unknown function	genetic	1	1	1	Negative Genetic
MAM33	YIL070C	Acidic protein of the mitochondrial matrix	genetic	1	1	1	Negative Genetic
SEC28	YIL076W	Epsilon-COP subunit of the coatomer	genetic	1	1	1	Negative Genetic
MEF2	YJL102W	Mitochondrial elongation factor involved in translational elongation	genetic	1	1	1	Negative Genetic
PET191	YJR034W	Protein required for assembly of cytochrome c oxidase	genetic	1	1	1	Negative Genetic
PTK2	YJR059W	Serine/threonine protein kinase	genetic	1	1	1	Negative Genetic
YKL075C	YKL075C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
SBA1	YKL117W	Co-chaperone that binds and regulates Hsp90 family chaperones	genetic	1	1	1	Negative Genetic
PGM1	YKL127W	Phosphoglucomutase, minor isoform	genetic	1	1	1	Negative Genetic
NEJ1	YLR265C	DNA end-binding protein required for nonhomologous end joining (NHEJ)	genetic	1	1	1	Negative Genetic
YAP1	YML007W	Basic leucine zipper (bZIP) transcription factor	genetic	1	1	1	Negative Genetic
YML053C	YML053C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
VAN1	YML115C	Component of the mannan polymerase I	genetic	1	1	1	Negative Genetic
NAM7	YMR080C	ATP-dependent RNA helicase of the SFI superfamily	genetic	1	1	1	Negative Genetic
MTG1	YMR097C	Putative GTPase peripheral to the mitochondrial inner membrane	genetic	1	1	1	Negative Genetic
SPS19	YNL202W	Peroxisomal 2,4-dienoyl-CoA reductase	genetic	1	1	1	Negative Genetic
MRPL17	YNL252C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
RPS19B	YNL302C	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
MRPS12	YNR036C	Mitochondrial protein	genetic	1	1	1	Negative Genetic
RIM1	YCR028C-A	ssDNA-binding protein essential for mitochondrial genome maintenance	genetic	1	1	1	Negative Genetic
RPS16B	YDL083C	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
SDH4	YDR178W	Membrane anchor subunit of succinate dehydrogenase (SDH)	genetic	1	1	1	Negative Genetic
UME6	YDR207C	Rpd3L histone deacetylase complex subunit	genetic	1	1	1	Negative Genetic
PEX3	YDR329C	Peroxisomal membrane protein (PMP)	genetic	1	1	1	Negative Genetic
SAC7	YDR389W	GTPase activating protein (GAP) for Rho1p	genetic	1	1	1	Negative Genetic
SXM1	YDR395W	Nuclear transport factor (karyopherin)	genetic	1	1	1	Negative Genetic
SDS3	YIL084C	Component of the Rpd3L histone deacetylase complex	genetic	1	1	1	Negative Genetic
RPI1	YIL119C	Transcription factor, allelic differences between S288C and Sigma1278b	genetic	1	1	1	Negative Genetic
RCY1	YJL204C	F-box protein involved in recycling endocytosed proteins	genetic	1	1	1	Negative Genetic
MRT4	YKL009W	Protein involved in mRNA turnover and ribosome assembly	genetic	1	1	1	Negative Genetic
VPS24	YKL041W	One of four subunits of the ESCRT-III complex	genetic	1	1	1	Negative Genetic
MUD2	YKL074C	Protein involved in early pre-mRNA splicing	genetic	1	1	1	Negative Genetic
SPE1	YKL184W	Ornithine decarboxylase	genetic	1	1	1	Negative Genetic
VPS13	YLL040C	Lipid transport protein involved in prospore membrane morphogenesis	genetic	1	1	1	Negative Genetic
SSK1	YLR006C	Cytoplasmic phosphorelay intermediate osmosensor and regulator	genetic	1	1	1	Negative Genetic
RPL22A	YLR061W	Ribosomal 60S subunit protein L22A	genetic	1	1	1	Negative Genetic
PUT1	YLR142W	Proline oxidase	genetic	1	1	1	Negative Genetic
PUS5	YLR165C	Pseudouridine synthase	genetic	1	1	1	Negative Genetic
MMR1	YLR190W	Phosphorylated protein of the mitochondrial outer membrane	genetic	1	1	1	Negative Genetic
SEC72	YLR292C	Non-essential subunit of Sec63 complex	genetic	1	1	1	Negative Genetic
NKP2	YLR315W	Central kinetochore protein and subunit of the Ctf19 complex	genetic	1	1	1	Negative Genetic
TSR2	YLR435W	Protein with a potential role in pre-rRNA processing	genetic	1	1	1	Negative Genetic
MRPL44	YMR225C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
YNL140C	YNL140C	Protein of unknown function	genetic	1	1	1	Negative Genetic
UBP2	YOR124C	Ubiquitin-specific protease	genetic	1	1	1	Negative Genetic
MCP1	YOR228C	Mitochondrial protein of unknown function involved in lipid homeostas	genetic	1	1	1	Negative Genetic
RDL2	YOR286W	Protein with rhodanese activity	genetic	1	1	1	Negative Genetic
TYE7	YOR344C	Serine-rich protein that contains a bHLH DNA binding motif	genetic	1	1	1	Negative Genetic
MEK1	YOR351C	Meiosis-specific serine/threonine protein kinase	genetic	1	1	1	Negative Genetic
YPL039W	YPL039W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
KAR9	YPL269W	Spindle positioning factor	genetic	1	1	1	Negative Genetic
SUT2	YPR009W	Zn2Cys6 family transcription factor	genetic	1	1	1	Negative Genetic
VMA13	YPR036W	Subunit H of the V1 peripheral membrane domain of V-ATPase	genetic	1	1	1	Negative Genetic
SPE3	YPR069C	Spermidine synthase	genetic	1	1	1	Negative Genetic
YNG2	YHR090C	Subunit of NuA4, an essential histone acetyltransferase complex	genetic	1	1	1	Negative Genetic
OCA2	YNL056W	Protein of unknown function	genetic	1	1	1	Negative Genetic
MSH6	YDR097C	Protein required for mismatch repair in mitosis and meiosis	genetic	1	1	1	Negative Genetic
RRD1	YIL153W	Peptidyl-prolyl cis/trans-isomerase	genetic	1	1	1	Negative Genetic
SAK1	YER129W	Upstream serine/threonine kinase for the SNF1 complex	genetic	1	1	1	Negative Genetic
TDH1	YJL052W	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1	genetic	1	1	1	Negative Genetic
RPD3	YNL330C	Histone deacetylase, component of both the Rpd3S and Rpd3L complexes	genetic	1	1	1	Positive Genetic
SAT4	YCR008W	Ser/Thr protein kinase involved in salt tolerance, nutrient response	genetic	1	1	1	Positive Genetic
REV3	YPL167C	Catalytic subunit of DNA polymerase zeta	genetic	1	1	1	Positive Genetic
RPS11B	YBR048W	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
PPH21	YDL134C	Catalytic subunit of protein phosphatase 2A, PP2A	genetic	1	1	1	Positive Genetic
PPE1	YHR075C	Protein with carboxyl methyl esterase activity	genetic	1	1	1	Positive Genetic
TUM1	YOR251C	Rhodanese domain sulfur transferase	genetic	1	1	1	Negative Genetic
RAM2	YKL019W	Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I	genetic	1	1	1	Positive Genetic
NHX1	YDR456W	Na+/H+ and K+/H+ exchanger	genetic	1	1	1	Negative Genetic
TOS3	YGL179C	Protein kinase	genetic	1	1	1	Negative Genetic
YVH1	YIR026C	Dual specificity protein phosphatase	genetic	1	1	1	Negative Genetic
UME1	YPL139C	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	genetic	1	1	1	Negative Genetic
MES1	YGR264C	Methionyl-tRNA synthetase	genetic	1	1	1	Positive Genetic
PTC3	YBL056W	Type 2C protein phosphatase (PP2C)	genetic	1	1	1	Negative Genetic
PHO85	YPL031C	Cyclin-dependent kinase	genetic	1	1	1	Positive Genetic
SAS3	YBL052C	Histone acetyltransferase catalytic subunit of NuA3 complex	genetic	1	1	1	Negative Genetic
RTT109	YLL002W	Histone acetyltransferase	genetic	1	1	1	Positive Genetic
KNS1	YLL019C	Protein kinase involved in negative regulation of PolIII transcription	genetic	1	1	1	Positive Genetic
RNR2	YJL026W	Ribonucleotide-diphosphate reductase (RNR), small subunit	genetic	1	1	1	Negative Genetic
SSK2	YNR031C	MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway	genetic	1	1	1	Negative Genetic
NUP2	YLR335W	Nucleoporin involved in nucleocytoplasmic transport	genetic	1	1	1	Negative Genetic
MSB2	YGR014W	Mucin family member involved in various signaling pathways	genetic	1	1	1	Negative Genetic
RAD51	YER095W	Strand exchange protein	genetic	1	1	1	Negative Genetic
PPH22	YDL188C	Catalytic subunit of protein phosphatase 2A, PP2A	genetic	1	1	1	Positive Genetic
SPO14	YKR031C	Phospholipase D	genetic	1	1	1	Negative Genetic
ZTA1	YBR046C	NADPH-dependent quinone reductase	genetic	1	1	1	Positive Genetic
KIN2	YLR096W	S/T protein kinase	genetic	1	1	1	Positive Genetic
YBT1	YLL048C	Transporter of the ATP-binding cassette (ABC) family	genetic	1	1	1	Positive Genetic
LIF1	YGL090W	Component of the DNA ligase IV complex	genetic	1	1	1	Negative Genetic
YNK1	YKL067W	Nucleoside diphosphate kinase	genetic	1	1	1	Negative Genetic
YPT1	YFL038C	Rab family GTPase	genetic	1	1	1	Negative Genetic
POL2	YNL262W	Catalytic subunit of DNA polymerase (II) epsilon	genetic	1	1	1	Positive Genetic
NPR1	YNL183C	Protein kinase	genetic	1	1	1	Positive Genetic
IRC20	YLR247C	E3 ubiquitin ligase and putative helicase	genetic	1	1	1	Negative Genetic
NTH2	YBR001C	Putative neutral trehalase, required for thermotolerance	genetic	1	1	1	Positive Genetic
TFB1	YDR311W	Subunit of TFIIH and nucleotide excision repair factor 3 complexes	genetic	1	1	1	Negative Genetic
RPB3	YIL021W	RNA polymerase II third largest subunit B44	genetic	1	1	1	Negative Genetic
MSH1	YHR120W	DNA-binding protein of the mitochondria	genetic	1	1	1	Negative Genetic
RPS10B	YMR230W	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Negative Genetic
ROT2	YBR229C	Glucosidase II catalytic subunit	genetic	1	1	1	Positive Genetic
MTM1	YGR257C	Mitochondrial protein of the mitochondrial carrier family	genetic	1	1	1	Negative Genetic
REV1	YOR346W	Deoxycytidyl transferase	genetic	1	1	1	Negative Genetic
OCA1	YNL099C	Putative protein tyrosine phosphatase	genetic	1	1	1	Negative Genetic
TUB4	YLR212C	Gamma-tubulin	genetic	1	1	1	Synthetic Growth Defect
MSN2	YMR037C	Stress-responsive transcriptional activator	genetic	1	1	1	Synthetic Rescue
MSN4	YKL062W	Stress-responsive transcriptional activator	genetic	1	1	1	Synthetic Rescue
TRX1	YLR043C	Cytoplasmic thioredoxin isoenzyme	genetic	1	1	1	Phenotypic Suppression
TRX2	YGR209C	Cytoplasmic thioredoxin isoenzyme	genetic	1	1	1	Phenotypic Suppression
HYP2	YEL034W	Translation elongation factor eIF-5A	genetic	1	1	1	Positive Genetic
CAF20	YOR276W	Phosphoprotein of the mRNA cap-binding complex	physical	1	1	1	Affinity Capture-RNA
CDC5	YMR001C	Polo-like kinase required for mitotic exit	genetic	1	1	1	Negative Genetic
ASA1	YPR085C	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	1	1	1	Positive Genetic
HTB1	YDR224C	Histone H2B	genetic	1	1	1	Positive Genetic
CDC53	YDL132W	Cullin	genetic	1	1	1	Positive Genetic
GSF2	YML048W	Endoplasmic reticulum (ER) localized integral membrane protein	genetic	1	1	1	Negative Genetic
DUN1	YDL101C	Cell-cycle checkpoint S/T protein kinase	genetic	1	1	1	Negative Genetic
CHK1	YBR274W	Serine/threonine kinase and DNA damage checkpoint effector	genetic	1	1	1	Synthetic Growth Defect
EGD1	YPL037C	Subunit beta1 of the nascent polypeptide-associated complex (NAC)	genetic	1	1	1	Negative Genetic
CDC9	YDL164C	DNA ligase I found in nucleus and mitochondria	genetic	1	1	1	Negative Genetic
COF1	YLL050C	Cofilin, involved in pH-dependent actin filament depolarization	genetic	1	1	1	Negative Genetic
AAC1	YMR056C	Mitochondrial inner membrane ADP/ATP translocator	physical	1	1	1	Affinity Capture-MS
AYR1	YIL124W	Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase	genetic	1	1	1	Negative Genetic
DSS1	YMR287C	3'-5' exoribonuclease	genetic	1	1	1	Negative Genetic
ERG10	YPL028W	Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase)	genetic	1	1	1	Negative Genetic
FUM1	YPL262W	Fumarase	genetic	1	1	1	Negative Genetic
CDC20	YGL116W	Activator of anaphase-promoting complex/cyclosome (APC/C)	genetic	1	1	1	Positive Genetic
DOP1	YDR141C	Protein involved in vesicular transport at trans-Golgi network (TGN)	genetic	1	1	1	Positive Genetic
ELM1	YKL048C	Serine/threonine protein kinase	genetic	1	1	1	Negative Genetic
CAT5	YOR125C	Protein required for ubiquinone (Coenzyme Q) biosynthesis	genetic	1	1	1	Negative Genetic
GRS1	YBR121C	Cytoplasmic and mitochondrial glycyl-tRNA synthase	physical	1	1	1	Affinity Capture-MS
EST1	YLR233C	TLC1 RNA-associated factor involved in telomere length regulation	genetic	1	1	1	Positive Genetic
ERG6	YML008C	Delta(24)-sterol C-methyltransferase	genetic	1	1	1	Synthetic Growth Defect
CIN8	YEL061C	Bipolar kinesin motor protein	genetic	1	1	1	Synthetic Growth Defect
INA1	YLR413W	Protein of unknown function	genetic	1	1	1	Negative Genetic
ADE17	YMR120C	Enzyme of 'de novo' purine biosynthesis	genetic	1	1	1	Negative Genetic
IRA1	YBR140C	GTPase-activating protein	physical	1	1	1	Affinity Capture-MS
DPB11	YJL090C	DNA replication initiation protein	genetic	1	1	1	Negative Genetic
HOM3	YER052C	Aspartate kinase (L-aspartate 4-P-transferase)	genetic	1	1	1	Negative Genetic
HAL5	YJL165C	Snf1p-related nutrient-responsive protein kinase	genetic	1	1	1	Positive Genetic
AHC1	YOR023C	Subunit of the Ada histone acetyltransferase complex	genetic	1	1	1	Negative Genetic
HAP3	YBL021C	Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex	genetic	1	1	1	Positive Genetic
FZO1	YBR179C	Mitofusin, protein involved in mitochondrial outer membrane fusion	genetic	1	1	1	Negative Genetic
FKH2	YNL068C	Forkhead family transcription factor	genetic	1	1	1	Positive Genetic
CPR3	YML078W	Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin)	genetic	1	1	1	Positive Genetic
FUS3	YBL016W	Mitogen-activated serine/threonine protein kinase involved in mating	genetic	1	1	1	Positive Genetic
FCF1	YDR339C	PINc domain endonuclease	genetic	1	1	1	Positive Genetic
GCY1	YOR120W	Glycerol dehydrogenase	genetic	1	1	1	Negative Genetic
ERG11	YHR007C	Lanosterol 14-alpha-demethylase	genetic	1	1	1	Negative Genetic
GDH2	YDL215C	NAD(+)-dependent glutamate dehydrogenase	genetic	1	1	1	Positive Genetic
AFG3	YER017C	Mitochondrial inner membrane m-AAA protease component	genetic	1	1	1	Negative Genetic
APL4	YPR029C	Gamma-adaptin	genetic	1	1	1	Negative Genetic
DCK1	YLR422W	Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1	genetic	1	1	1	Positive Genetic
BUD27	YFL023W	Unconventional prefoldin protein involved in translation initiation	genetic	1	1	1	Negative Genetic
FMN1	YDR236C	Riboflavin kinase, produces riboflavin monophosphate (FMN)	genetic	1	1	1	Negative Genetic
GEP4	YHR100C	Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase)	genetic	1	1	1	Negative Genetic
AFT1	YGL071W	Transcription factor involved in iron utilization and homeostasis	genetic	1	1	1	Synthetic Growth Defect
GZF3	YJL110C	GATA zinc finger protein	physical	1	1	1	PCA
BNA6	YFR047C	Quinolinate phosphoribosyl transferase	genetic	1	1	1	Negative Genetic
DLS1	YJL065C	Subunit of ISW2/yCHRAC chromatin accessibility complex	genetic	1	1	1	Negative Genetic
ASK1	YKL052C	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	1	1	1	Negative Genetic
AIM4	YBR194W	Protein proposed to be associated with the nuclear pore complex	genetic	1	1	1	Negative Genetic
GMH1	YKR030W	Golgi membrane protein of unknown function	genetic	1	1	1	Negative Genetic
APC11	YDL008W	Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	1	1	1	Negative Genetic
CDC27	YBL084C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	1	1	1	Negative Genetic
CEP3	YMR168C	Essential kinetochore protein	genetic	1	1	1	Negative Genetic
COG6	YNL041C	Component of the conserved oligomeric Golgi complex	genetic	1	1	1	Negative Genetic
ELP3	YPL086C	Subunit of Elongator complex	genetic	1	1	1	Positive Genetic
ELP4	YPL101W	Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex	genetic	1	1	1	Positive Genetic
AMD1	YML035C	AMP deaminase	genetic	1	1	1	Negative Genetic
IES2	YNL215W	Protein that associates with the INO80 chromatin remodeling complex	genetic	1	1	1	Negative Genetic
IES3	YLR052W	Subunit of the INO80 chromatin remodeling complex	genetic	1	1	1	Negative Genetic
CBF1	YJR060W	Basic helix-loop-helix (bHLH) protein	genetic	1	1	1	Positive Genetic
CLC1	YGR167W	Clathrin light chain	genetic	1	1	1	Negative Genetic
CTF8	YHR191C	Subunit of a complex with Ctf18p	genetic	1	1	1	Negative Genetic
HOP2	YGL033W	Meiosis-specific protein that localizes to chromosomes	genetic	1	1	1	Negative Genetic
IOC4	YMR044W	Member of a complex (Isw1b) with Isw1p and Ioc2p	genetic	1	1	1	Negative Genetic
FIG4	YNL325C	Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase	genetic	1	1	1	Negative Genetic
GOS1	YHL031C	v-SNARE protein involved in Golgi transport	genetic	1	1	1	Negative Genetic
HSF1	YGL073W	Trimeric heat shock transcription factor	genetic	1	1	1	Negative Genetic
HAP4	YKL109W	Transcription factor	genetic	1	1	1	Negative Genetic
CSG2	YBR036C	Endoplasmic reticulum membrane protein	genetic	1	1	1	Negative Genetic
CCS1	YMR038C	Copper chaperone for superoxide dismutase Sod1p	genetic	1	1	1	Negative Genetic
FCP1	YMR277W	Carboxy-terminal domain (CTD) phosphatase	genetic	1	1	1	Positive Genetic
GPB2	YAL056W	Multistep regulator of cAMP-PKA signaling	physical	1	1	1	Affinity Capture-Western
AKR1	YDR264C	Palmitoyl transferase involved in protein palmitoylation	genetic	1	1	1	Negative Genetic
INP53	YOR109W	Polyphosphatidylinositol phosphatase	genetic	1	1	1	Positive Genetic
HFA1	YMR207C	Mitochondrial acetyl-coenzyme A carboxylase	genetic	1	1	1	Positive Genetic
HMT1	YBR034C	Nuclear SAM-dependent mono- and asymmetric methyltransferase	physical	1	1	1	Affinity Capture-MS
CDC19	YAL038W	Pyruvate kinase	physical	1	1	1	Affinity Capture-MS
ATP1	YBL099W	Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase	genetic	1	1	1	Negative Genetic
CCH1	YGR217W	Voltage-gated high-affinity calcium channel	genetic	1	1	1	Negative Genetic
CPR7	YJR032W	Peptidyl-prolyl cis-trans isomerase (cyclophilin)	genetic	1	1	1	Positive Genetic
APN2	YBL019W	Class II abasic (AP) endonuclease involved in repair of DNA damage	genetic	1	1	1	Negative Genetic
HPA2	YPR193C	Tetrameric histone acetyltransferase	genetic	1	1	1	Negative Genetic
BCS1	YDR375C	Protein translocase and chaperone required for Complex III assembly	genetic	1	1	1	Negative Genetic
BET4	YJL031C	Alpha subunit of Type II geranylgeranyltransferase	genetic	1	1	1	Negative Genetic
DOM34	YNL001W	Protein that facilitates ribosomal subunit dissociation	genetic	1	1	1	Positive Genetic
COX14	YML129C	Mitochondrial cytochrome c oxidase (complex IV) assembly factor	genetic	1	1	1	Negative Genetic
CBP1	YJL209W	Mitochondrial protein, regulator of COB mRNA stability and translation	genetic	1	1	1	Negative Genetic
ALG1	YBR110W	Mannosyltransferase	genetic	1	1	1	Positive Genetic
EGT2	YNL327W	Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase	genetic	1	1	1	Negative Genetic
ERG2	YMR202W	C-8 sterol isomerase	genetic	1	1	1	Negative Genetic
BAP3	YDR046C	Amino acid permease	genetic	1	1	1	Positive Genetic
BOL3	YAL046C	Protein involved in Fe-S cluster transfer to mitochondrial clients	genetic	1	1	1	Negative Genetic
CPR5	YDR304C	Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the ER	genetic	1	1	1	Positive Genetic
COQ10	YOL008W	Coenzyme Q (ubiquinone) binding protein	genetic	1	1	1	Negative Genetic
BRL1	YHR036W	Essential nuclear envelope/ER integral membrane protein	genetic	1	1	1	Negative Genetic
GEP7	YGL057C	Protein of unknown function	genetic	1	1	1	Negative Genetic
CRS1	YNL247W	Cysteinyl-tRNA synthetase	genetic	1	1	1	Negative Genetic
CUE3	YGL110C	Subunit of ribosome-associated quality control trigger complex (RQT)	genetic	1	1	1	Negative Genetic
FIG2	YCR089W	Cell wall adhesin, expressed specifically during mating	genetic	1	1	1	Negative Genetic
INA22	YIR024C	F1F0 ATP synthase peripheral stalk assembly factor	genetic	1	1	1	Negative Genetic
CGI121	YML036W	Component of the EKC/KEOPS complex	genetic	1	1	1	Negative Genetic
CTP1	YBR291C	Mitochondrial inner membrane citrate transporter	genetic	1	1	1	Positive Genetic
CBS1	YDL069C	Mitochondrial translational activator of the COB mRNA	genetic	1	1	1	Negative Genetic
CYK3	YDL117W	SH3-domain protein located in the bud neck and cytokinetic actin ring	genetic	1	1	1	Positive Genetic
DSF1	YEL070W	Mannitol dehydrogenase	genetic	1	1	1	Negative Genetic
FLO11	YIR019C	GPI-anchored cell surface glycoprotein (flocculin)	genetic	1	1	1	Positive Genetic
ADE12	YNL220W	Adenylosuccinate synthase	genetic	1	1	1	Negative Genetic
ALD4	YOR374W	Mitochondrial aldehyde dehydrogenase	genetic	1	1	1	Negative Genetic
HEM12	YDR047W	Uroporphyrinogen decarboxylase	genetic	1	1	1	Negative Genetic
GSH1	YJL101C	Gamma glutamylcysteine synthetase	genetic	1	1	1	Negative Genetic
IGD1	YFR017C	Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity	genetic	1	1	1	Negative Genetic
IPT1	YDR072C	Inositolphosphotransferase	genetic	1	1	1	Negative Genetic
APJ1	YNL077W	Hsp40 chaperone with a role in SUMO-mediated protein degradation	genetic	1	1	1	Positive Genetic
ATG21	YPL100W	Phosphoinositide binding protein	genetic	1	1	1	Negative Genetic
CMR3	YPR013C	Putative zinc finger protein	genetic	1	1	1	Positive Genetic
CYC3	YAL039C	Cytochrome c heme lyase (holocytochrome c synthase)	genetic	1	1	1	Negative Genetic
GPI12	YMR281W	ER membrane protein involved in the second step of GPI anchor assembly	genetic	1	1	1	Positive Genetic
COQ8	YGL119W	ATPase required for ubiquinone biosynthesis and respiratory growth	genetic	1	1	1	Negative Genetic
ERG24	YNL280C	C-14 sterol reductase	genetic	1	1	1	Negative Genetic
COX10	YPL172C	Heme A:farnesyltransferase	genetic	1	1	1	Negative Genetic
ERR2	YPL281C	Enolase, a phosphopyruvate hydratase	physical	1	1	1	Affinity Capture-MS
CDC50	YCR094W	Endosomal protein that interacts with phospholipid flippase Drs2p	genetic	1	1	1	Negative Genetic
CTA1	YDR256C	Catalase A	genetic	1	1	1	Negative Genetic
EAR1	YMR171C	Specificity factor required for Rsp5p-dependent ubiquitination	genetic	1	1	1	Negative Genetic
COA1	YIL157C	Mitochondrial inner membrane protein	genetic	1	1	1	Negative Genetic
ERG4	YGL012W	C-24(28) sterol reductase	genetic	1	1	1	Negative Genetic
BAP2	YBR068C	High-affinity leucine permease	genetic	1	1	1	Negative Genetic
CEM1	YER061C	Mitochondrial beta-keto-acyl synthase	genetic	1	1	1	Negative Genetic
INO1	YJL153C	Inositol-3-phosphate synthase	genetic	1	1	1	Negative Genetic
FAD1	YDL045C	Flavin adenine dinucleotide (FAD) synthetase	genetic	1	1	1	Negative Genetic
DAN4	YJR151C	Cell wall mannoprotein	genetic	1	1	1	Positive Genetic
ATG41	YPL250C	Protein of unknown function	genetic	1	1	1	Negative Genetic
DLD1	YDL174C	Major mitochondrial D-lactate dehydrogenase	genetic	1	1	1	Negative Genetic
COX16	YJL003W	Mitochondrial inner membrane protein	genetic	1	1	1	Negative Genetic
DIT2	YDR402C	N-formyltyrosine oxidase	genetic	1	1	1	Positive Genetic
BER1	YLR412W	Protein involved in microtubule-related processes	genetic	1	1	1	Negative Genetic
HEM25	YDL119C	Mitochondrial glycine transporter	genetic	1	1	1	Negative Genetic
HMX1	YLR205C	ER localized heme oxygenase	genetic	1	1	1	Negative Genetic
DFR1	YOR236W	Dihydrofolate reductase involved in tetrahydrofolate biosynthesis	genetic	1	1	1	Negative Genetic
AGP1	YCL025C	Broad-specificity, low-affinity amino acid permease	genetic	1	1	1	Positive Genetic
FEN2	YCR028C	Plasma membrane H+-pantothenate symporter	genetic	1	1	1	Negative Genetic
DGK1	YOR311C	Diacylglycerol kinase	genetic	1	1	1	Negative Genetic
ALK2	YBL009W	Atypical protein kinase	genetic	1	1	1	Negative Genetic
IMA1	YGR287C	Major isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase)	genetic	1	1	1	Negative Genetic
AIM33	YML087C	Protein of unknown function, highly conserved across species	genetic	1	1	1	Positive Genetic
GPI11	YDR302W	ER membrane protein involved in a late step of GPI anchor assembly	genetic	1	1	1	Positive Genetic
FMT1	YBL013W	Methionyl-tRNA formyltransferase	genetic	1	1	1	Negative Genetic
ADF1	YCL058W-A	Transcriptional repressor encoded by the FYV5 antisense strand	genetic	1	1	1	Negative Genetic