Standard name Systematic name Name description Description
HHT1 YBR010W Histone H3 Histone H3; core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT2); regulated by acetylation, methylation, and phosphorylation; H3K14 acetylation plays an important role in the unfolding of strongly positioned nucleosomes during repair of UV damage
Visualize the interactome of HHT1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 64

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.983 0.969 0.930
Mito NaN NaN 0.126

GFP localization & abundance

GFP localization GFP abundance
nucleus 213000

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HHT1 3 1 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ASF1 YJL115W Nucleosome assembly factor physical 22 5 21 Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Co-crystal Structure, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
SIR3 YLR442C Silencing protein physical 17 3 14 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Protein-peptide, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 16 3 16 Reconstituted Complex, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
HHF1 YBR009C Histone H4 physical 16 6 15 Reconstituted Complex, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-localization, Co-localization, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, FRET, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
RTT106 YNL206C Histone chaperone physical 16 3 12 Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
RTT109 YLL002W Histone acetyltransferase physical 14 3 13 Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, Biochemical Activity, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
ASF1 YJL115W Nucleosome assembly factor genetic 12 4 9 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Dosage Growth Defect, Phenotypic Suppression, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Suppression, Negative Genetic, Negative Genetic, Synthetic Growth Defect
HTA1 YDR225W Histone H2A physical 10 4 10 Reconstituted Complex, Co-purification, Co-purification, Co-purification, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase physical 10 4 9 Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, Co-crystal Structure
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 10 4 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Co-localization, Affinity Capture-Western
HTZ1 YOL012C Histone variant H2AZ physical 8 4 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-localization, Affinity Capture-MS, FRET, Reconstituted Complex
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) physical 8 3 8 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
SPP1 YPL138C Subunit of COMPASS (Set1C) physical 8 5 6 Protein-peptide, Reconstituted Complex, Affinity Capture-Luminescence, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Protein-peptide
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex physical 8 4 6 Reconstituted Complex, Protein-peptide, Affinity Capture-Western, Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Protein-peptide, Protein-peptide
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p physical 7 2 7 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 7 3 6 Synthetic Rescue, Synthetic Rescue, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Rescue
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 6 3 6 Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Reconstituted Complex, Biochemical Activity, Biochemical Activity
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex physical 6 3 6 Protein-peptide, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Protein-peptide, Protein-peptide
HHF2 YNL030W Histone H4 physical 6 3 6 Co-localization, Co-localization, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family physical 6 3 5 Biochemical Activity, Protein-peptide, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 6 3 5 Synthetic Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Suppression
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes physical 6 3 5 Reconstituted Complex, Affinity Capture-MS, Protein-peptide, Protein-peptide, Reconstituted Complex, Reconstituted Complex
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex physical 6 5 4 Affinity Capture-Western, Far Western, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Protein-peptide
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex physical 6 4 4 Affinity Capture-Western, Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Reconstituted Complex, Protein-peptide
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex physical 6 3 4 Affinity Capture-Western, Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Affinity Capture-Western, Protein-peptide
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I physical 6 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex physical 6 3 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western
RRN9 YMR270C Protein involved in promoting high level transcription of rDNA physical 6 3 3 Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
HHF1 YBR009C Histone H4 genetic 5 5 5 Phenotypic Enhancement, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression, Dosage Lethality
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation physical 5 4 5 Co-localization, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity
HTB1 YDR224C Histone H2B physical 5 3 5 Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 5 3 5 Dosage Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
HHT2 YNL031C Histone H3 physical 5 3 5 Affinity Capture-MS, Co-localization, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
HIF1 YLL022C Non-essential component of the HAT-B histone acetyltransferase complex physical 5 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 5 2 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex physical 5 1 5 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 5 4 4 Synthetic Growth Defect, Synthetic Growth Defect, Dosage Growth Defect, Synthetic Rescue, Phenotypic Suppression
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription physical 5 3 4 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Protein-peptide
HTA1 YDR225W Histone H2A genetic 5 3 4 Synthetic Rescue, Positive Genetic, Positive Genetic, Positive Genetic, Synthetic Growth Defect
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 5 3 4 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic, Negative Genetic
PDP3 YLR455W Component of the NuA3b histone acetyltransferase complex physical 5 3 4 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Protein-peptide
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes physical 5 3 4 Affinity Capture-MS, Reconstituted Complex, Protein-peptide, Reconstituted Complex, Reconstituted Complex
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 5 2 4 Phenotypic Suppression, Positive Genetic, Positive Genetic, Phenotypic Suppression, Positive Genetic
HHT2 YNL031C Histone H3 genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ORC1 YML065W Largest subunit of the origin recognition complex physical 5 4 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex
RAD53 YPL153C DNA damage response kinase genetic 5 3 3 Dosage Growth Defect, Dosage Growth Defect, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 5 3 3 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect
RRN10 YBL025W Protein involved in promoting high level transcription of rDNA physical 5 3 3 Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 4 3 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex physical 4 3 4 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes physical 4 3 4 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation genetic 4 3 4 Dosage Rescue, Phenotypic Suppression, Synthetic Lethality, Phenotypic Suppression
HTA2 YBL003C Histone H2A physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
JHD2 YJR119C JmjC domain family histone demethylase physical 4 2 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Affinity Capture-Western
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 4 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Rescue
HIR3 YJR140C Subunit of the HIR complex genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 4 4 3 Negative Genetic, Dosage Growth Defect, Positive Genetic, Synthetic Rescue
FPR4 YLR449W Peptidyl-prolyl cis-trans isomerase (PPIase) physical 4 3 3 Reconstituted Complex, Affinity Capture-MS, Biochemical Activity, Reconstituted Complex
SIR3 YLR442C Silencing protein genetic 4 3 3 Phenotypic Suppression, Phenotypic Suppression, Dosage Rescue, Synthetic Rescue
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 4 3 3 Reconstituted Complex, Protein-peptide, Affinity Capture-MS, Affinity Capture-MS
RSC2 YLR357W Component of the RSC chromatin remodeling complex physical 4 3 3 Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western
SPT6 YGR116W Nucleosome remodeling protein physical 4 3 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Protein-peptide
CSE4 YKL049C Centromeric histone H3-like protein genetic 4 3 3 Dosage Lethality, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
UAF30 YOR295W Subunit of UAF (upstream activation factor) complex physical 4 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
LEO1 YOR123C Component of the Paf1 complex genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling physical 4 3 2 Far Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex
MCM2 YBL023C Protein involved in DNA replication physical 4 3 2 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
BYE1 YKL005C Negative regulator of transcription elongation physical 4 3 2 Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Reconstituted Complex
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex physical 4 2 2 Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Affinity Capture-Western
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling physical 3 3 3 Affinity Capture-Western, Protein-peptide, Reconstituted Complex
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 3 3 3 Dosage Lethality, Synthetic Growth Defect, Synthetic Rescue
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 3 3 3 Dosage Lethality, Synthetic Rescue, Synthetic Lethality
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) physical 3 3 3 Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex
SPT2 YER161C Protein involved in negative regulation of transcription genetic 3 3 3 Dosage Rescue, Negative Genetic, Synthetic Lethality
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 3 3 3 Synthetic Growth Defect, Negative Genetic, Synthetic Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 3 2 3 Affinity Capture-MS, Biochemical Activity, Biochemical Activity
BDF1 YLR399C BET family transcriptional regulator physical 3 2 3 Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
HAT2 YEL056W Subunit of the Hat1p-Hat2p histone acetyltransferase complex physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Protein-peptide
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains physical 3 2 3 Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western
HIR1 YBL008W Subunit of the HIR complex physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 3 2 3 Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex
INO80 YGL150C Nucleosome spacing factor physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
RTT106 YNL206C Histone chaperone genetic 3 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Protein-peptide
IOC4 YMR044W Member of a complex (Isw1b) with Isw1p and Ioc2p physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RSC8 YFR037C Component of the RSC chromatin remodeling complex physical 3 2 3 Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
RTT109 YLL002W Histone acetyltransferase genetic 3 2 3 Phenotypic Suppression, Synthetic Growth Defect, Synthetic Growth Defect
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex physical 3 2 3 Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes physical 3 2 3 Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes physical 3 2 3 Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
HPR1 YDR138W Subunit of THO/TREX complexes genetic 3 2 3 Synthetic Lethality, Phenotypic Suppression, Phenotypic Suppression
IPL1 YPL209C Aurora kinase of chromosomal passenger complex physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RIF1 YBR275C Protein involved in control of DNA replication genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RSC4 YKR008W Component of the RSC chromatin remodeling complex physical 3 3 2 Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes physical 3 3 2 Reconstituted Complex, Co-crystal Structure, Affinity Capture-MS
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) physical 3 3 2 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Dosage Lethality
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
DST1 YGL043W General transcription elongation factor TFIIS genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 3 2 2 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
HTB1 YDR224C Histone H2B genetic 3 2 2 Positive Genetic, Positive Genetic, Synthetic Growth Defect
KAP123 YER110C Karyopherin beta physical 3 2 2 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement
SET3 YKR029C Defining member of the SET3 histone deacetylase complex physical 3 2 2 Affinity Capture-Western, Affinity Capture-Luminescence, Affinity Capture-Western
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Suppression
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Dosage Lethality
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Dosage Lethality
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Suppression
CSE4 YKL049C Centromeric histone H3-like protein physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
BRE1 YDL074C E3 ubiquitin ligase genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
IKI3 YLR384C Subunit of Elongator complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RAD18 YCR066W E3 ubiquitin ligase genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
RPS30A YLR287C-A Protein component of the small (40S) ribosomal subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
BMH2 YDR099W 14-3-3 protein, minor isoform physical 3 2 1 Protein-peptide, Protein-peptide, Reconstituted Complex
JHD1 YER051W JmjC domain family histone demethylase specific for H3-K36 physical 3 2 1 Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 2 2 2 chromatin immunoprecipitation-qPCR evidence, qualitative western immunoblotting evidence
STP1 YDR463W Transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation regulation 2 2 2 qualitative western immunoblotting evidence, quantitative western immunoblotting evidence
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes regulation 2 2 2 DNA to cDNA expression microarray evidence, qualitative western immunoblotting evidence
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 2 2 2 Affinity Capture-MS, Biochemical Activity
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
ELP2 YGR200C Subunit of Elongator complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
ADA2 YDR448W Transcription coactivator physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
FUN30 YAL019W Snf2p family member with ATP-dependent chromatin remodeling activity physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
HIR2 YOR038C Subunit of HIR nucleosome assembly complex physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
NHP6A YPR052C High-mobility group (HMG) protein physical 2 2 2 Affinity Capture-MS, PCA
SRM1 YGL097W Nucleotide exchange factor for Gsp1p physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
VPS75 YNL246W NAP family histone chaperone physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
RPH1 YER169W JmjC domain-containing histone demethylase physical 2 2 2 Biochemical Activity, Protein-peptide
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
RSC1 YGR056W Component of the RSC chromatin remodeling complex physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 2 2 2 Affinity Capture-Western, Biochemical Activity
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex physical 2 2 2 Affinity Capture-Western, Protein-peptide
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
RSC58 YLR033W Component of the RSC chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
RSC9 YML127W Component of the RSC chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
PUF2 YPR042C PUF family mRNA-binding protein physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
IOC3 YFR013W Subunit of the Isw1a complex physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 2 2 2 Phenotypic Suppression, Negative Genetic
SML1 YML058W Ribonucleotide reductase inhibitor genetic 2 2 2 Dosage Lethality, Synthetic Rescue
SUB1 YMR039C Transcriptional regulator genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RAD52 YML032C Protein involved in homologous recombination genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 2 2 2 Synthetic Rescue, Synthetic Growth Defect
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex regulation 2 1 2 qualitative western immunoblotting evidence, qualitative western immunoblotting evidence
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
RAD53 YPL153C DNA damage response kinase physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
HTB2 YBL002W Histone H2B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSH155 YMR288W U2-snRNP associated splicing factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
RPB10 YOR210W RNA polymerase subunit ABC10-beta physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPC10 YHR143W-A RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RPB2 YOR151C RNA polymerase II second largest subunit B150 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
UBP6 YFR010W Ubiquitin-specific protease genetic 2 1 2 Negative Genetic, Negative Genetic
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 2 1 2 Negative Genetic, Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 2 1 2 Negative Genetic, Negative Genetic
YDR249C YDR249C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
PIR5 YJL160C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
SKA1 YKL023W SKI complex-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 2 1 2 Negative Genetic, Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 1 2 Negative Genetic, Negative Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 2 1 2 Negative Genetic, Negative Genetic
SVL3 YPL032C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
HST4 YDR191W NAD(+)-dependent protein deacetylase genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 2 1 2 Negative Genetic, Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 2 1 2 Negative Genetic, Negative Genetic
SAC3 YDR159W mRNA export factor genetic 2 1 2 Negative Genetic, Negative Genetic
EIS1 YMR031C Component of the eisosome required for proper eisosome assembly physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 2 1 2 Negative Genetic, Negative Genetic
NHP6B YBR089C-A High-mobility group (HMG) protein physical 2 2 1 PCA, Reconstituted Complex
SWD2 YKL018W Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex physical 2 2 1 Co-localization, Protein-peptide
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 2 2 1 Positive Genetic, Synthetic Rescue
SGO1 YOR073W Component of the spindle checkpoint physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
CTR1 YPR124W High-affinity copper transporter of plasma membrane genetic 2 2 1 Phenotypic Enhancement, Synthetic Growth Defect
CDC73 YLR418C Component of the Paf1p complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BMH1 YER177W 14-3-3 protein, major isoform physical 2 1 1 Protein-peptide, Protein-peptide
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
ADA2 YDR448W Transcription coactivator genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CIN8 YEL061C Bipolar kinesin motor protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SPP1 YPL138C Subunit of COMPASS (Set1C) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
IES6 YEL044W Component of the INO80 chromatin remodeling complex physical 2 1 1 Reconstituted Complex, Reconstituted Complex
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 2 1 1 Reconstituted Complex, Reconstituted Complex
HOS4 YIL112W Subunit of the Set3 complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MIF2 YKL089W Centromeric CDEIII region binding protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
POL32 YJR043C Third subunit of DNA polymerase delta genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
TUB3 YML124C Alpha-tubulin genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 2 1 1 Negative Genetic, Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BRE5 YNR051C Ubiquitin protease cofactor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
BAS1 YKR099W Myb-related transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes regulation 1 1 1 DNA to cDNA expression microarray evidence
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation regulation 1 1 1 DNA to cDNA expression microarray evidence
RPH1 YER169W JmjC domain-containing histone demethylase regulation 1 1 1 quantitative western immunoblotting evidence
NHP6A YPR052C High-mobility group (HMG) protein regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
OAF1 YAL051W Oleate-activated transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SCH9 YHR205W AGC family protein kinase regulation 1 1 1 qualitative western immunoblotting evidence
NHP6B YBR089C-A High-mobility group (HMG) protein regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression regulation 1 1 1 quantitative polymerase chain reaction evidence
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) regulation 1 1 1 qualitative western immunoblotting evidence
HHT2 YNL031C Histone H3 regulation 1 1 1 quantitative western immunoblotting evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Synthetic Growth Defect
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs physical 1 1 1 Affinity Capture-MS
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs genetic 1 1 1 Dosage Lethality
CTF3 YLR381W Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p genetic 1 1 1 Dosage Lethality
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs genetic 1 1 1 Positive Genetic
ENP2 YGR145W Component of the SSU physical 1 1 1 Affinity Capture-MS
BRX1 YOL077C Nucleolar protein physical 1 1 1 Affinity Capture-MS
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing physical 1 1 1 Affinity Capture-MS
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 1 1 1 Affinity Capture-MS
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function genetic 1 1 1 Negative Genetic
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly physical 1 1 1 Affinity Capture-MS
HAS1 YMR290C ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
GCD6 YDR211W Catalytic epsilon subunit of the translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 Affinity Capture-MS
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
CDC33 YOL139C Translation initiation factor eIF4E physical 1 1 1 Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 1 1 1 Reconstituted Complex
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex physical 1 1 1 Affinity Capture-MS
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Affinity Capture-MS
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme physical 1 1 1 Affinity Capture-MS
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) genetic 1 1 1 Positive Genetic
APL3 YBL037W Alpha-adaptin physical 1 1 1 Affinity Capture-MS
ARP2 YDL029W Essential component of the Arp2/3 complex physical 1 1 1 Affinity Capture-MS
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
BEM2 YER155C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Affinity Capture-MS
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 1 1 1 Affinity Capture-MS
BOI2 YER114C Protein involved in polar growth physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Affinity Capture-MS
BNI1 YNL271C Formin physical 1 1 1 Affinity Capture-MS
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex physical 1 1 1 Reconstituted Complex
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
CHC1 YGL206C Clathrin heavy chain physical 1 1 1 Affinity Capture-MS
CIP1 YPL014W Cyclin-dependent kinase inhibitor physical 1 1 1 Affinity Capture-MS
CTF18 YMR078C Subunit of a complex with Ctf8p physical 1 1 1 Affinity Capture-MS
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) physical 1 1 1 Co-localization
CYR1 YJL005W Adenylate cyclase physical 1 1 1 Affinity Capture-MS
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly physical 1 1 1 Affinity Capture-MS
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) physical 1 1 1 Affinity Capture-MS
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase physical 1 1 1 Affinity Capture-MS
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking physical 1 1 1 Affinity Capture-MS
HAT2 YEL056W Subunit of the Hat1p-Hat2p histone acetyltransferase complex genetic 1 1 1 Dosage Growth Defect
ECM5 YMR176W Subunit of the Snt2C complex physical 1 1 1 Affinity Capture-Western
HHF2 YNL030W Histone H4 genetic 1 1 1 Phenotypic Suppression
DPB4 YDR121W Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex physical 1 1 1 Affinity Capture-MS
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
ECM29 YHL030W Scaffold protein physical 1 1 1 Affinity Capture-MS
END3 YNL084C EH domain-containing protein involved in endocytosis physical 1 1 1 Affinity Capture-MS
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase physical 1 1 1 Affinity Capture-MS
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) physical 1 1 1 Affinity Capture-MS
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase physical 1 1 1 Affinity Capture-MS
ATG26 YLR189C UDP-glucose:sterol glucosyltransferase physical 1 1 1 Affinity Capture-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Positive Genetic
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring physical 1 1 1 Affinity Capture-MS
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Affinity Capture-MS
DBP8 YHR169W ATPase, putative RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex physical 1 1 1 Affinity Capture-MS
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
CSI1 YMR025W Subunit of the Cop9 signalosome genetic 1 1 1 Negative Genetic
ABF2 YMR072W Mitochondrial DNA-binding protein physical 1 1 1 Affinity Capture-MS
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
DAL3 YIR032C Ureidoglycolate lyase genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
ECM30 YLR436C Protein of unknown function physical 1 1 1 Affinity Capture-MS
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor physical 1 1 1 Affinity Capture-MS
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-MS
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 1 1 1 Affinity Capture-MS
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) physical 1 1 1 Affinity Capture-MS
EDC3 YEL015W Non-essential conserved protein with a role in mRNA decapping physical 1 1 1 Affinity Capture-MS
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization physical 1 1 1 Affinity Capture-MS
AKL1 YBR059C Ser/Thr protein kinase physical 1 1 1 Affinity Capture-MS
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
CDC53 YDL132W Cullin physical 1 1 1 Affinity Capture-MS
FAA4 YMR246W Long chain fatty acyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) physical 1 1 1 Affinity Capture-MS
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) genetic 1 1 1 Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector physical 1 1 1 Affinity Capture-MS
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
ENV7 YPL236C Vacuolar membrane protein kinase physical 1 1 1 Biochemical Activity
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
ATG12 YBR217W Ubiquitin-like modifier involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network physical 1 1 1 Affinity Capture-MS
ACS2 YLR153C Acetyl-coA synthetase isoform physical 1 1 1 Affinity Capture-MS
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Phenotypic Suppression
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
GIP2 YER054C Putative regulatory subunit of protein phosphatase Glc7p physical 1 1 1 Affinity Capture-MS
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription physical 1 1 1 Affinity Capture-MS
APE1 YKL103C Vacuolar aminopeptidase yscI physical 1 1 1 Affinity Capture-MS
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Affinity Capture-MS
CIN8 YEL061C Bipolar kinesin motor protein physical 1 1 1 Affinity Capture-MS
FAA1 YOR317W Long chain fatty acyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
MAG1 YER142C 3-methyl-adenine DNA glycosylase physical 1 1 1 Affinity Capture-MS
MGT1 YDL200C DNA repair methyltransferase (6-O-methylguanine-DNA methylase) physical 1 1 1 Affinity Capture-MS
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes physical 1 1 1 Affinity Capture-MS
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TUP1 YCR084C General repressor of transcription in complex with Cyc8p physical 1 1 1 Reconstituted Complex
TUP1 YCR084C General repressor of transcription in complex with Cyc8p genetic 1 1 1 Synthetic Rescue
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Phenotypic Suppression
KAP123 YER110C Karyopherin beta genetic 1 1 1 Synthetic Growth Defect
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Biochemical Activity
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Phenotypic Suppression
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways physical 1 1 1 Affinity Capture-MS
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member physical 1 1 1 Affinity Capture-MS
SLX9 YGR081C Protein required for pre-rRNA processing physical 1 1 1 Affinity Capture-MS
HIF1 YLL022C Non-essential component of the HAT-B histone acetyltransferase complex genetic 1 1 1 Dosage Growth Defect
VAC7 YNL054W Integral vacuolar membrane protein physical 1 1 1 Affinity Capture-MS
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family physical 1 1 1 Affinity Capture-MS
NHP6A YPR052C High-mobility group (HMG) protein genetic 1 1 1 Dosage Lethality
YCR087C-A YCR087C-A Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
STP1 YDR463W Transcription factor physical 1 1 1 Affinity Capture-MS
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) physical 1 1 1 Affinity Capture-MS
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Affinity Capture-MS
MIG1 YGL035C Transcription factor involved in glucose repression physical 1 1 1 Affinity Capture-MS
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Negative Genetic
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 physical 1 1 1 Reconstituted Complex
RPH1 YER169W JmjC domain-containing histone demethylase genetic 1 1 1 Phenotypic Suppression
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange physical 1 1 1 Affinity Capture-Western
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 1 1 1 Phenotypic Suppression
JHD2 YJR119C JmjC domain family histone demethylase genetic 1 1 1 Synthetic Rescue
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-Western
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Two-hybrid
YBP2 YGL060W Central kinetochore associated protein physical 1 1 1 Affinity Capture-Western
HST3 YOR025W Sirtuin, histone H3 deacetylase physical 1 1 1 Biochemical Activity
ORC2 YBR060C Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-Western
ORC3 YLL004W Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-Western
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) physical 1 1 1 Affinity Capture-Western
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes physical 1 1 1 Affinity Capture-Western
TOP1 YOL006C Topoisomerase I physical 1 1 1 Affinity Capture-Western
SNT2 YGL131C Subunit of Snt2C complex, RING finger ubiquitin ligase (E3) physical 1 1 1 Affinity Capture-Western
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Synthetic Rescue
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Synthetic Growth Defect
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex physical 1 1 1 Affinity Capture-Western
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex physical 1 1 1 Affinity Capture-Western
STE7 YDL159W Signal transducing MAP kinase kinase physical 1 1 1 Affinity Capture-MS
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Positive Genetic
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
MED8 YBR193C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Reconstituted Complex
MED1 YPR070W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Reconstituted Complex
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Reconstituted Complex
HTL1 YCR020W-B Component of the RSC chromatin remodeling complex physical 1 1 1 Reconstituted Complex
LDB7 YBL006C Component of the RSC chromatin remodeling complex physical 1 1 1 Reconstituted Complex
NPL6 YMR091C Component of the RSC chromatin remodeling complex physical 1 1 1 Reconstituted Complex
RSC3 YDR303C Component of the RSC chromatin remodeling complex physical 1 1 1 Reconstituted Complex
RSC30 YHR056C Component of the RSC chromatin remodeling complex physical 1 1 1 Reconstituted Complex
RSC6 YCR052W Component of the RSC chromatin remodeling complex physical 1 1 1 Reconstituted Complex
SFH1 YLR321C Component of the RSC chromatin remodeling complex physical 1 1 1 Reconstituted Complex
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Reconstituted Complex
SNF12 YNR023W 73 kDa subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Reconstituted Complex
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Reconstituted Complex
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Reconstituted Complex
SWP82 YFL049W Member of the SWI/SNF chromatin remodeling complex physical 1 1 1 Reconstituted Complex
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance physical 1 1 1 Affinity Capture-MS
RFA3 YJL173C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) physical 1 1 1 Affinity Capture-MS
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
RPC17 YJL011C RNA polymerase III subunit C17 physical 1 1 1 Affinity Capture-MS
RPO31 YOR116C RNA polymerase III largest subunit C160 physical 1 1 1 Affinity Capture-MS
RPC53 YDL150W RNA polymerase III subunit C53 physical 1 1 1 Affinity Capture-MS
VPS60 YDR486C Protein involved in late endosome to vacuole transport physical 1 1 1 Affinity Capture-MS
MOT3 YMR070W Transcriptional repressor, activator physical 1 1 1 Affinity Capture-MS
RPC31 YNL151C RNA polymerase III subunit C31 physical 1 1 1 Affinity Capture-MS
RPC37 YKR025W RNA polymerase III subunit C37 physical 1 1 1 Affinity Capture-MS
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
YMR315W YMR315W Protein with NADP(H) oxidoreductase activity physical 1 1 1 Affinity Capture-MS
YMR315W YMR315W Protein with NADP(H) oxidoreductase activity genetic 1 1 1 Negative Genetic
PHO2 YDL106C Homeobox transcription factor physical 1 1 1 Affinity Capture-MS
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p physical 1 1 1 Affinity Capture-MS
TOP3 YLR234W DNA Topoisomerase III physical 1 1 1 Affinity Capture-MS
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p physical 1 1 1 Affinity Capture-MS
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex physical 1 1 1 Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RRN9 YMR270C Protein involved in promoting high level transcription of rDNA genetic 1 1 1 Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation physical 1 1 1 Affinity Capture-MS
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 1 1 1 Dosage Lethality
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
TAF4 YMR005W TFIID subunit (48 kDa) physical 1 1 1 Affinity Capture-MS
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
RVS161 YCR009C Amphiphysin-like lipid raft protein physical 1 1 1 Affinity Capture-MS
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
YME2 YMR302C Integral inner mitochondrial membrane protein physical 1 1 1 Affinity Capture-MS
ICS2 YBR157C Protein of unknown function physical 1 1 1 Affinity Capture-MS
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Affinity Capture-MS
IFA38 YBR159W Microsomal beta-keto-reductase physical 1 1 1 Affinity Capture-MS
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis physical 1 1 1 Affinity Capture-MS
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin physical 1 1 1 Affinity Capture-MS
MSN4 YKL062W Stress-responsive transcriptional activator physical 1 1 1 Affinity Capture-MS
MAE1 YKL029C Mitochondrial malic enzyme physical 1 1 1 Affinity Capture-MS
PNO1 YOR145C Essential nucleolar protein required for pre-18S rRNA processing physical 1 1 1 Affinity Capture-MS
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis physical 1 1 1 Affinity Capture-MS
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
NPC2 YDL046W Sterol transport protein and functional homolog of human NPC2/He1 physical 1 1 1 Affinity Capture-MS
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRP7 YNL005C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
SDA1 YGR245C Protein required for actin organization and passage through Start physical 1 1 1 Affinity Capture-MS
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity physical 1 1 1 Affinity Capture-MS
SAN1 YDR143C Ubiquitin-protein ligase physical 1 1 1 Affinity Capture-MS
MRM1 YOR201C Ribose methyltransferase physical 1 1 1 Affinity Capture-MS
PRE5 YMR314W Alpha 6 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
UTP20 YBL004W Component of the small-subunit (SSU) processome physical 1 1 1 Affinity Capture-MS
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
LSC1 YOR142W Alpha subunit of succinyl-CoA ligase physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
YPK1 YKL126W S/T protein kinase physical 1 1 1 Affinity Capture-MS
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes physical 1 1 1 Affinity Capture-MS
MAK5 YBR142W Essential nucleolar protein physical 1 1 1 Affinity Capture-MS
SER1 YOR184W 3-phosphoserine aminotransferase physical 1 1 1 Affinity Capture-MS
YPL150W YPL150W Protein kinase of unknown cellular role physical 1 1 1 Affinity Capture-MS
SSF1 YHR066W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
NOC4 YPR144C Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP7 YER082C Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP7 YER082C Nucleolar protein genetic 1 1 1 Negative Genetic
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein physical 1 1 1 Affinity Capture-MS
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
MRC1 YCL061C S-phase checkpoint protein required for DNA replication physical 1 1 1 Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-MS
TOP2 YNL088W Topoisomerase II physical 1 1 1 Affinity Capture-MS
VMR1 YHL035C Vacuolar membrane protein physical 1 1 1 Affinity Capture-MS
RFC3 YNL290W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
YGL039W YGL039W Aldehyde reductase physical 1 1 1 Affinity Capture-MS
NOP14 YDL148C Nucleolar protein physical 1 1 1 Affinity Capture-MS
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis physical 1 1 1 Affinity Capture-MS
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-MS
LSP1 YPL004C Eisosome core component physical 1 1 1 Affinity Capture-MS
MRPL7 YDR237W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
RBG2 YGR173W Protein with a role in translation physical 1 1 1 Affinity Capture-MS
RCL1 YOL010W Endonuclease that cleaves pre-rRNA at site A2 for 18S rRNA biogenesis physical 1 1 1 Affinity Capture-MS
RBG1 YAL036C Member of the DRG family of GTP-binding proteins physical 1 1 1 Affinity Capture-MS
PBA1 YLR199C Protein involved in 20S proteasome assembly physical 1 1 1 Affinity Capture-MS
IPI3 YNL182C Component of the Rix1 complex and pre-replicative complexes (pre-RCs) physical 1 1 1 Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 1 1 1 Affinity Capture-MS
YAP1801 YHR161C Protein of the AP180 family, involved in clathrin cage assembly physical 1 1 1 Affinity Capture-MS
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
MRX6 YNL295W Mitochondrial ribosome-associated protein physical 1 1 1 Affinity Capture-MS
YCL019W YCL019W Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YDR261W-B YDR261W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
SEC28 YIL076W Epsilon-COP subunit of the coatomer physical 1 1 1 Affinity Capture-MS
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs physical 1 1 1 Affinity Capture-MS
YDR341C YDR341C Arginyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
VMA6 YLR447C Subunit d of the V0 integral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
PDR16 YNL231C Phosphatidylinositol transfer protein (PITP) physical 1 1 1 Affinity Capture-MS
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex physical 1 1 1 Affinity Capture-MS
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p physical 1 1 1 Affinity Capture-MS
RPA49 YNL248C RNA polymerase I subunit A49 physical 1 1 1 Affinity Capture-MS
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export physical 1 1 1 Affinity Capture-MS
ORC5 YNL261W Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-MS
NOG2 YNR053C Putative GTPase physical 1 1 1 Affinity Capture-MS
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis physical 1 1 1 Affinity Capture-MS
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit physical 1 1 1 Affinity Capture-MS
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex physical 1 1 1 Affinity Capture-MS
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 1 1 1 Affinity Capture-MS
TCB1 YOR086C Lipid-binding ER protein involved in ER-plasma membrane tethering physical 1 1 1 Affinity Capture-MS
NEW1 YPL226W Translation termination and ribosome biogenesis factor physical 1 1 1 Affinity Capture-MS
WHI4 YDL224C Putative RNA binding protein physical 1 1 1 Affinity Capture-MS
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Affinity Capture-MS
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins physical 1 1 1 Affinity Capture-MS
PSP1 YDR505C Asn and gln rich protein of unknown function physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
URB1 YKL014C Protein required for the normal accumulation of 25S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
TGL4 YKR089C Multifunctional lipase/hydrolase/phospholipase physical 1 1 1 Affinity Capture-MS
STE5 YDR103W Pheromone-responsive MAPK scaffold protein physical 1 1 1 Affinity Capture-MS
MSH2 YOL090W Protein that binds to DNA mismatches physical 1 1 1 Affinity Capture-MS
SLA1 YBL007C Cytoskeletal protein binding protein physical 1 1 1 Affinity Capture-MS
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p physical 1 1 1 Affinity Capture-MS
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering physical 1 1 1 Affinity Capture-MS
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis physical 1 1 1 Affinity Capture-MS
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
TRP5 YGL026C Tryptophan synthase physical 1 1 1 Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-MS
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
MHF2 YDL160C-A Component of the heterotetrameric MHF histone-fold complex physical 1 1 1 Affinity Capture-MS
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway physical 1 1 1 Affinity Capture-MS
PCT1 YGR202C Cholinephosphate cytidylyltransferase physical 1 1 1 Affinity Capture-MS
TOA2 YKL058W TFIIA small subunit physical 1 1 1 Affinity Capture-MS
TRP2 YER090W Anthranilate synthase physical 1 1 1 Affinity Capture-MS
RCM1 YNL022C rRNA m5C methyltransferase physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis physical 1 1 1 Affinity Capture-MS
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination physical 1 1 1 Affinity Capture-MS
YJR029W YJR029W Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YLR227W-B YLR227W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
RAD59 YDL059C Protein involved DNA double-strand break repair physical 1 1 1 Affinity Capture-MS
SPC29 YPL124W Inner plaque spindle pole body (SPB) component physical 1 1 1 Affinity Capture-MS
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Affinity Capture-MS
TIF35 YDR429C eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
PHO81 YGR233C Cyclin-dependent kinase (CDK) inhibitor physical 1 1 1 Affinity Capture-MS
YPR089W YPR089W Protein of unknown function physical 1 1 1 Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Affinity Capture-MS
MSS116 YDR194C Mitochondrial transcription elongation factor physical 1 1 1 Affinity Capture-MS
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
PDR5 YOR153W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
PRS1 YKL181W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Affinity Capture-MS
YCL020W YCL020W Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 1 1 1 Affinity Capture-MS
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Affinity Capture-MS
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 1 1 1 Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
RRB1 YMR131C Specific assembly chaperone for ribosomal protein Rpl3p physical 1 1 1 Affinity Capture-MS
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes physical 1 1 1 Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 1 1 1 Affinity Capture-MS
VAC8 YEL013W Vacuole-specific Myo2p receptor physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
TAH11 YJR046W DNA replication licensing factor physical 1 1 1 Affinity Capture-MS
MAG2 YLR427W Cytoplasmic protein of unknown function physical 1 1 1 Affinity Capture-MS
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage physical 1 1 1 Affinity Capture-MS
MIT1 YEL007W Transcriptional regulator of pseudohyphal growth physical 1 1 1 Affinity Capture-MS
MIT1 YEL007W Transcriptional regulator of pseudohyphal growth genetic 1 1 1 Negative Genetic
IKI3 YLR384C Subunit of Elongator complex physical 1 1 1 Affinity Capture-MS
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter physical 1 1 1 Affinity Capture-MS
NOC2 YOR206W Protein involved in ribosome biogenesis physical 1 1 1 Affinity Capture-MS
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes physical 1 1 1 Affinity Capture-MS
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Synthetic Rescue
VTC4 YJL012C Vacuolar membrane polyphosphate polymerase physical 1 1 1 Affinity Capture-MS
YKR018C YKR018C Protein of unknown function physical 1 1 1 Affinity Capture-MS
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding physical 1 1 1 Affinity Capture-MS
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone physical 1 1 1 Affinity Capture-MS
HSL1 YKL101W Nim1p-related protein kinase physical 1 1 1 Affinity Capture-MS
VID27 YNL212W Cytoplasmic protein of unknown function physical 1 1 1 Affinity Capture-MS
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs physical 1 1 1 Affinity Capture-MS
RIX7 YLL034C Putative ATPase of the AAA family physical 1 1 1 Affinity Capture-MS
SPO14 YKR031C Phospholipase D physical 1 1 1 Affinity Capture-MS
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response physical 1 1 1 Affinity Capture-MS
PIM1 YBL022C ATP-dependent Lon protease physical 1 1 1 Affinity Capture-MS
SMC2 YFR031C Subunit of the condensin complex physical 1 1 1 Affinity Capture-MS
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Affinity Capture-MS
SEC3 YER008C Subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
RSE1 YML049C Protein involved in pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
TAF2 YCR042C TFIID subunit (150 kDa) physical 1 1 1 Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Phenotypic Enhancement
YOR142W-B YOR142W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
TAO3 YIL129C Component of the RAM signaling network physical 1 1 1 Affinity Capture-MS
YMR050C YMR050C Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
TIF6 YPR016C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
YBL005W-B YBL005W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting physical 1 1 1 Affinity Capture-MS
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
LEO1 YOR123C Component of the Paf1 complex physical 1 1 1 Affinity Capture-MS
MIR1 YJR077C Mitochondrial phosphate carrier physical 1 1 1 Affinity Capture-MS
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex physical 1 1 1 Affinity Capture-MS
RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p physical 1 1 1 Affinity Capture-MS
JSN1 YJR091C Member of the Puf family of RNA-binding proteins physical 1 1 1 Affinity Capture-MS
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 1 1 1 Affinity Capture-MS
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing physical 1 1 1 Affinity Capture-MS
MUK1 YPL070W Guanine nucleotide exchange factor (GEF) physical 1 1 1 Affinity Capture-MS
SKN7 YHR206W Nuclear response regulator and transcription factor physical 1 1 1 Affinity Capture-MS
PGC1 YPL206C Phosphatidylglycerol phospholipase C physical 1 1 1 Affinity Capture-MS
RPA43 YOR340C RNA polymerase I subunit A43 physical 1 1 1 Affinity Capture-MS
TWF1 YGR080W Twinfilin physical 1 1 1 Affinity Capture-MS
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
HXT7 YDR342C High-affinity glucose transporter physical 1 1 1 Affinity Capture-MS
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
HIS3 YOR202W Imidazoleglycerol-phosphate dehydratase physical 1 1 1 Affinity Capture-MS
UPC2 YDR213W Sterol regulatory element binding protein physical 1 1 1 Affinity Capture-MS
MTC1 YJL123C Protein of unknown function that may interact with ribosomes physical 1 1 1 Affinity Capture-MS
LSB1 YGR136W Negative regulator of actin nucleation-promoting factor activity physical 1 1 1 Affinity Capture-MS
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Affinity Capture-MS
MRH4 YGL064C Mitochondrial ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Affinity Capture-MS
NAB6 YML117W Putative RNA-binding protein physical 1 1 1 Affinity Capture-MS
NAN1 YPL126W U3 snoRNP protein physical 1 1 1 Affinity Capture-MS
NUM1 YDR150W Protein required for nuclear migration physical 1 1 1 Affinity Capture-MS
MRPL22 YNL177C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Affinity Capture-MS
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p physical 1 1 1 Affinity Capture-MS
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p genetic 1 1 1 Phenotypic Enhancement
LCB5 YLR260W Minor sphingoid long-chain base kinase physical 1 1 1 Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
RKM5 YLR137W Protein lysine methyltransferase physical 1 1 1 Affinity Capture-MS
TFG1 YGR186W TFIIF (Transcription Factor II) largest subunit physical 1 1 1 Affinity Capture-MS
POL3 YDL102W Catalytic subunit of DNA polymerase delta physical 1 1 1 Affinity Capture-MS
TOM40 YMR203W Component of the TOM (translocase of outer membrane) complex physical 1 1 1 Affinity Capture-MS
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase physical 1 1 1 Affinity Capture-MS
LYS14 YDR034C Transcriptional activator involved in regulating lysine biosynthesis physical 1 1 1 Affinity Capture-MS
SWI6 YLR182W Transcription cofactor physical 1 1 1 Affinity Capture-MS
SRP40 YKR092C Nucleolar serine-rich protein physical 1 1 1 Affinity Capture-MS
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder physical 1 1 1 Affinity Capture-MS
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex physical 1 1 1 Affinity Capture-MS
SGD1 YLR336C Essential nuclear protein physical 1 1 1 Affinity Capture-MS
NUP49 YGL172W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-MS
PIK1 YNL267W Phosphatidylinositol 4-kinase physical 1 1 1 Affinity Capture-MS
KIN1 YDR122W S/T protein kinase physical 1 1 1 Affinity Capture-MS
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
YAP1802 YGR241C Protein of the AP180 family, involved in clathrin cage assembly physical 1 1 1 Affinity Capture-MS
MSB1 YOR188W Protein of unknown function physical 1 1 1 Affinity Capture-MS
PRP39 YML046W U1 snRNP protein involved in splicing physical 1 1 1 Affinity Capture-MS
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 Affinity Capture-MS
SNX41 YDR425W Sorting nexin physical 1 1 1 Affinity Capture-MS
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling physical 1 1 1 Affinity Capture-MS
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth physical 1 1 1 Affinity Capture-MS
NUP157 YER105C Subunit of the inner ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles physical 1 1 1 Affinity Capture-MS
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Negative Genetic
SPA2 YLL021W Component of the polarisome physical 1 1 1 Affinity Capture-MS
YTA6 YPL074W Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family physical 1 1 1 Affinity Capture-MS
SCD5 YOR329C Protein required for normal actin organization and endocytosis physical 1 1 1 Affinity Capture-MS
STB4 YMR019W Putative transcription factor physical 1 1 1 Affinity Capture-MS
SLH1 YGR271W Subunit of ribosome-associated quality control trigger complex (RQT) physical 1 1 1 Affinity Capture-MS
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease physical 1 1 1 Affinity Capture-MS
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
MCM6 YGL201C Protein involved in DNA replication physical 1 1 1 Affinity Capture-MS
YCG1 YDR325W Subunit of the condensin complex physical 1 1 1 Affinity Capture-MS
SDD3 YOL098C Putative metalloprotease physical 1 1 1 Affinity Capture-MS
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
RIF1 YBR275C Protein involved in control of DNA replication physical 1 1 1 Affinity Capture-MS
MOT1 YPL082C Essential protein involved in regulation of transcription physical 1 1 1 Affinity Capture-MS
TOR1 YJR066W PIK-related protein kinase and rapamycin target physical 1 1 1 Affinity Capture-MS
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Phenotypic Suppression
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex physical 1 1 1 Affinity Capture-MS
TAE1 YBR261C AdoMet-dependent proline methyltransferase physical 1 1 1 Affinity Capture-MS
NRD1 YNL251C RNA-binding subunit of Nrd1 complex physical 1 1 1 Affinity Capture-MS
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation physical 1 1 1 Affinity Capture-MS
PDR11 YIL013C ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
PAM1 YDR251W Essential protein of unknown function physical 1 1 1 Affinity Capture-MS
MCM3 YEL032W Protein involved in DNA replication physical 1 1 1 Affinity Capture-MS
RGT1 YKL038W Glucose-responsive transcription factor physical 1 1 1 Affinity Capture-MS
SMC3 YJL074C Subunit of the multiprotein cohesin complex physical 1 1 1 Affinity Capture-MS
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
SET5 YHR207C Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 physical 1 1 1 Affinity Capture-Western
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
HST2 YPL015C Cytoplasmic NAD(+)-dependent protein deacetylase physical 1 1 1 Biochemical Activity
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex physical 1 1 1 Affinity Capture-Western
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 1 1 1 Affinity Capture-MS
RPB4 YJL140W RNA polymerase II subunit B32 physical 1 1 1 Affinity Capture-MS
RPB5 YBR154C RNA polymerase subunit ABC27 physical 1 1 1 Affinity Capture-MS
RPB7 YDR404C RNA polymerase II subunit B16 physical 1 1 1 Affinity Capture-MS
RPB8 YOR224C RNA polymerase subunit ABC14.5 physical 1 1 1 Affinity Capture-MS
RPB11 YOL005C RNA polymerase II subunit B12.5 physical 1 1 1 Affinity Capture-MS
IOC2 YLR095C Subunit of the Isw1b complex physical 1 1 1 Affinity Capture-MS
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 1 1 1 Negative Genetic
SPT6 YGR116W Nucleosome remodeling protein genetic 1 1 1 Phenotypic Suppression
HIR3 YJR140C Subunit of the HIR complex physical 1 1 1 Affinity Capture-MS
RMP1 YLR145W Subunit of RNase MRP physical 1 1 1 Affinity Capture-RNA
LSM1 YJL124C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-RNA
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex physical 1 1 1 Reconstituted Complex
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex physical 1 1 1 Reconstituted Complex
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Affinity Capture-Western
UBC5 YDR059C Ubiquitin-conjugating enzyme physical 1 1 1 Affinity Capture-Western
SCM3 YDL139C Nonhistone component of centromeric chromatin physical 1 1 1 Reconstituted Complex
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon physical 1 1 1 Affinity Capture-Western
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Rescue
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity physical 1 1 1 Biochemical Activity
MAD2 YJL030W Component of the spindle-assembly checkpoint complex physical 1 1 1 Reconstituted Complex
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase physical 1 1 1 Biochemical Activity
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-Western
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase physical 1 1 1 Affinity Capture-MS
SPN1 YPR133C Protein involved in RNA polymerase II transcription physical 1 1 1 Reconstituted Complex
SGO1 YOR073W Component of the spindle checkpoint genetic 1 1 1 Dosage Rescue
REB1 YBR049C RNA polymerase I enhancer binding protein physical 1 1 1 FRET
SWR1 YDR334W Swi2/Snf2-related ATPase physical 1 1 1 Reconstituted Complex
SCH9 YHR205W AGC family protein kinase physical 1 1 1 Biochemical Activity
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MES1 YGR264C Methionyl-tRNA synthetase physical 1 1 1 Affinity Capture-RNA
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Synthetic Rescue
RAD3 YER171W 5' to 3' DNA helicase genetic 1 1 1 Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Phenotypic Suppression
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
YML119W YML119W Putative protein of unknown function genetic 1 1 1 Positive Genetic
MCM22 YJR135C Outer kinetochore protein and component of the Ctf3 subcomplex genetic 1 1 1 Dosage Lethality
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Synthetic Growth Defect
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Synthetic Growth Defect
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex genetic 1 1 1 Synthetic Rescue
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Phenotypic Suppression
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Phenotypic Suppression
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Rescue
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Synthetic Rescue
SLX4 YLR135W Endonuclease involved in processing DNA genetic 1 1 1 Synthetic Rescue
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Synthetic Rescue
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Synthetic Lethality
MSL1 YIR009W U2B component of U2 snRNP genetic 1 1 1 Synthetic Lethality
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
SIR1 YKR101W Protein involved in silencing at mating-type loci HML and HMR genetic 1 1 1 Phenotypic Enhancement
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Positive Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Positive Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Positive Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Synthetic Lethality
RAD17 YOR368W Checkpoint protein genetic 1 1 1 Synthetic Growth Defect
RAD24 YER173W Checkpoint protein genetic 1 1 1 Synthetic Growth Defect
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Positive Genetic
TAF3 YPL011C TFIID subunit (47 kDa) genetic 1 1 1 Positive Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Positive Genetic
YDR524C-B YDR524C-B Putative protein of unknown function genetic 1 1 1 Positive Genetic
WTM1 YOR230W Transcriptional modulator genetic 1 1 1 Positive Genetic
SRB6 YBR253W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
TRS31 YDR472W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
LCP5 YER127W Essential protein involved in maturation of 18S rRNA genetic 1 1 1 Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
UTP25 YIL091C Nucleolar protein genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p genetic 1 1 1 Negative Genetic
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RPL5 YPL131W Ribosomal 60S subunit protein L5 genetic 1 1 1 Negative Genetic
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Negative Genetic
YAL064W YAL064W Protein of unknown function genetic 1 1 1 Negative Genetic
PAA1 YDR071C Polyamine acetyltransferase genetic 1 1 1 Negative Genetic
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 1 1 1 Negative Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
TVP23 YDR084C Integral membrane protein genetic 1 1 1 Negative Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Negative Genetic
MSC2 YDR205W Endoplasmic reticulum zinc transporter genetic 1 1 1 Negative Genetic
SXM1 YDR395W Nuclear transport factor (karyopherin) genetic 1 1 1 Negative Genetic
YFH7 YFR007W Putative kinase with similarity to the PRK/URK/PANK kinase subfamily genetic 1 1 1 Negative Genetic
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Negative Genetic
OSH3 YHR073W Member of an oxysterol-binding protein family genetic 1 1 1 Negative Genetic
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions genetic 1 1 1 Negative Genetic
PRY3 YJL078C GPI-anchored cell wall protein involved in export of sterols genetic 1 1 1 Negative Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Phenotypic Suppression
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex genetic 1 1 1 Phenotypic Suppression
VBA5 YKR105C Plasma membrane protein of the Major Facilitator Superfamily (MFS) genetic 1 1 1 Negative Genetic
YLL053C YLL053C Putative protein genetic 1 1 1 Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Negative Genetic
VBA1 YMR088C Permease of basic amino acids in the vacuolar membrane genetic 1 1 1 Negative Genetic
IMP1 YMR150C Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Negative Genetic
YMR242W-A YMR242W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RSM19 YNR037C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
LAG2 YOL025W Protein that negatively regulates the SCF E3-ubiquitin ligase genetic 1 1 1 Negative Genetic
THI20 YOL055C Trifunctional enzyme of thiamine biosynthesis, degradation and salvage genetic 1 1 1 Negative Genetic
YOL131W YOL131W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SEY1 YOR165W Dynamin-like GTPase that mediates homotypic ER fusion genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Phenotypic Suppression
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Synthetic Growth Defect
RPL20B YOR312C Ribosomal 60S subunit protein L20B genetic 1 1 1 Phenotypic Suppression
RPB9 YGL070C RNA polymerase II subunit B12.6 genetic 1 1 1 Synthetic Lethality
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Positive Genetic
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation physical 1 1 1 Affinity Capture-MS
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Synthetic Rescue
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Negative Genetic
CCE1 YKL011C Mitochondrial cruciform cutting endonuclease physical 1 1 1 Affinity Capture-MS
ELC1 YPL046C Elongin C, conserved among eukaryotes genetic 1 1 1 Synthetic Rescue
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Positive Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
APL4 YPR029C Gamma-adaptin physical 1 1 1 Affinity Capture-MS
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Affinity Capture-MS
ARH1 YDR376W Oxidoreductase of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
ATP20 YPR020W Subunit g of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Negative Genetic
DAL82 YNL314W Positive regulator of allophanate inducible genes genetic 1 1 1 Negative Genetic
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Negative Genetic
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
BMT2 YBR141C Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex physical 1 1 1 Affinity Capture-Western
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Synthetic Growth Defect
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex physical 1 1 1 Affinity Capture-MS
COG6 YNL041C Component of the conserved oligomeric Golgi complex physical 1 1 1 Affinity Capture-MS
ELP3 YPL086C Subunit of Elongator complex physical 1 1 1 Affinity Capture-MS
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex physical 1 1 1 Affinity Capture-Western
GRC3 YLL035W Polynucleotide kinase present on rDNA genetic 1 1 1 Negative Genetic
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein physical 1 1 1 FRET
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Phenotypic Suppression
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex physical 1 1 1 Affinity Capture-MS
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion genetic 1 1 1 Synthetic Lethality
CBF2 YGR140W Essential kinetochore protein genetic 1 1 1 Dosage Lethality
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation physical 1 1 1 Affinity Capture-MS
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 1 1 1 Synthetic Growth Defect
BNR1 YIL159W Formin physical 1 1 1 Affinity Capture-MS
DAL80 YKR034W Negative regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Negative Genetic
DBP1 YPL119C ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 1 1 1 Synthetic Growth Defect
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Biochemical Activity
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector physical 1 1 1 Affinity Capture-MS
AZF1 YOR113W Zinc-finger transcription factor physical 1 1 1 Affinity Capture-MS
CLA4 YNL298W Cdc42p-activated signal transducing kinase physical 1 1 1 Affinity Capture-MS
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Phenotypic Suppression
EUC1 YMR111C Sequence-specific DNA binding protein genetic 1 1 1 Negative Genetic
ECM21 YBL101C Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p physical 1 1 1 Affinity Capture-MS
GTA1 YEL043W Protein of unknown function genetic 1 1 1 Positive Genetic
HEM14 YER014W Protoporphyrinogen oxidase physical 1 1 1 Affinity Capture-MS
CUE1 YMR264W Ubiquitin-binding protein physical 1 1 1 Affinity Capture-MS
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein physical 1 1 1 Affinity Capture-MS
CUE3 YGL110C Subunit of ribosome-associated quality control trigger complex (RQT) physical 1 1 1 Affinity Capture-MS
CSR1 YLR380W Phosphatidylinositol transfer protein genetic 1 1 1 Negative Genetic
CHA1 YCL064C Catabolic L-serine (L-threonine) deaminase physical 1 1 1 Affinity Capture-MS
AIM26 YKL037W Protein of unknown function genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) physical 1 1 1 Affinity Capture-MS
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b genetic 1 1 1 Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Phenotypic Suppression
GVP36 YIL041W BAR domain protein that localizes to early and late Golgi vesicles physical 1 1 1 Affinity Capture-MS
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
GSC2 YGR032W Catalytic subunit of 1,3-beta-glucan synthase physical 1 1 1 Affinity Capture-MS
DFG16 YOR030W Probable multiple transmembrane protein genetic 1 1 1 Negative Genetic
EFR3 YMR212C Protein required for Stt4-containing PI kinase complex localization physical 1 1 1 Affinity Capture-MS
FAA3 YIL009W Long chain fatty acyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
ALK1 YGL021W Atypical protein kinase physical 1 1 1 Affinity Capture-MS
GRS2 YPR081C Glycine-tRNA synthetase, not expressed under normal growth conditions physical 1 1 1 Affinity Capture-MS
AFG1 YEL052W Protein that may act as a chaperone for cytochrome c oxidase subunits physical 1 1 1 Affinity Capture-MS
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase physical 1 1 1 Affinity Capture-MS
EXO5 YBR163W Mitochondrial 5'-3' exonuclease and sliding exonuclease physical 1 1 1 Affinity Capture-MS
CUP1-1 YHR053C Metallothionein genetic 1 1 1 Dosage Rescue
DBR1 YKL149C RNA lariat debranching enzyme genetic 1 1 1 Negative Genetic