UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
18 |
6 |
11 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-purification, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
12 |
3 |
8 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
9 |
3 |
8 |
Positive Genetic, Positive Genetic, Synthetic Growth Defect, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Dosage Rescue, Positive Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
9 |
2 |
7 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
9 |
1 |
7 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
9 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
8 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
8 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
7 |
2 |
6 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
7 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
7 |
2 |
5 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PHO80 |
YOL001W |
Cyclin |
genetic |
7 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
7 |
1 |
5 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
7 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
7 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
6 |
3 |
6 |
Negative Genetic, Negative Genetic, Synthetic Rescue, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
6 |
3 |
6 |
Negative Genetic, Negative Genetic, Synthetic Rescue, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
6 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
6 |
3 |
5 |
Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
6 |
2 |
5 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic |
POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
6 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
6 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
6 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
genetic |
6 |
4 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Dosage Rescue, Synthetic Growth Defect, Phenotypic Enhancement |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
6 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
6 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
6 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
6 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Dosage Rescue |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
6 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
5 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
5 |
3 |
4 |
Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
5 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
5 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SCS3 |
YGL126W |
Protein required for normal ER membrane biosynthesis in response to ER |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ATG21 |
YPL100W |
Phosphoinositide binding protein |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
AGE2 |
YIL044C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
5 |
2 |
2 |
Negative Genetic, Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic |
ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
4 |
3 |
4 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
4 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
4 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
4 |
3 |
3 |
Negative Genetic, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
4 |
3 |
3 |
Positive Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
4 |
2 |
3 |
Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
4 |
2 |
3 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TMA19 |
YKL056C |
Protein that associates with ribosomes |
genetic |
4 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
ERG4 |
YGL012W |
C-24(28) sterol reductase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CLG1 |
YGL215W |
Cyclin-like protein that interacts with Pho85p |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
4 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CTP1 |
YBR291C |
Mitochondrial inner membrane citrate transporter |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
4 |
2 |
2 |
Positive Genetic, Positive Genetic, Phenotypic Suppression, Phenotypic Suppression |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
4 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
4 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
3 |
3 |
3 |
PCA, Affinity Capture-MS, Affinity Capture-RNA |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
3 |
3 |
3 |
PCA, Co-crystal Structure, Affinity Capture-MS |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
3 |
3 |
3 |
Negative Genetic, Positive Genetic, Synthetic Growth Defect |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
3 |
3 |
3 |
Synthetic Rescue, Negative Genetic, Positive Genetic |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Proximity Label-MS, Affinity Capture-MS |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Proximity Label-MS, Affinity Capture-MS |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
3 |
1 |
3 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
MFT1 |
YML062C |
Subunit of the THO complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RXT3 |
YDL076C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
UBC13 |
YDR092W |
E2 ubiquitin-conjugating enzyme |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Positive Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
TED1 |
YIL039W |
GPI-glycan remodelase |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Dosage Rescue |
SEY1 |
YOR165W |
Dynamin-like GTPase that mediates homotypic ER fusion |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Positive Genetic |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Positive Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
GPX2 |
YBR244W |
Phospholipid hydroperoxide glutathione peroxidase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
PHO13 |
YDL236W |
Conserved phosphatase acting as a metabolite repair enzyme |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PRP28 |
YDR243C |
Pre-mRNA splicing factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PAC11 |
YDR488C |
Dynein intermediate chain, microtubule motor protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PHB1 |
YGR132C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
SOP4 |
YJL192C |
ER-membrane protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
OAR1 |
YKL055C |
Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
YLR152C |
YLR152C |
Putative protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SAS2 |
YMR127C |
Histone acetyltransferase (HAT) catalytic subunit of the SAS complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
URA5 |
YML106W |
Major orotate phosphoribosyltransferase (OPRTase) isozyme |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TIR4 |
YOR009W |
Cell wall mannoprotein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RSB1 |
YOR049C |
Sphingoid long-chain base (LCB) efflux transporter |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS5 |
YOR069W |
Nexin-1 homolog |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VAM10 |
YOR068C |
Protein involved in vacuole morphogenesis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ULA1 |
YPL003W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
AGE1 |
YDR524C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BER1 |
YLR412W |
Protein involved in microtubule-related processes |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
2 |
2 |
2 |
PCA, Affinity Capture-MS |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
2 |
2 |
2 |
PCA, Affinity Capture-MS |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
GEM1 |
YAL048C |
Outer mitochondrial membrane GTPase, subunit of the ERMES complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Rescue |
ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BCK2 |
YER167W |
Serine/threonine-rich protein involved in PKC1 signaling pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ASR1 |
YPR093C |
Ubiquitin ligase that modifies and regulates RNA Pol II |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ADH6 |
YMR318C |
NADPH-dependent medium chain alcohol dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UTP5 |
YDR398W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS75 |
YNL246W |
NAP family histone chaperone |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
THI6 |
YPL214C |
Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SKI3 |
YPR189W |
Ski complex component and TPR protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SAP190 |
YKR028W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
INP51 |
YIL002C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POP4 |
YBR257W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MTR4 |
YJL050W |
RNA duplex-sensing translocase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DID4 |
YKL002W |
Class E Vps protein of the ESCRT-III complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TFA2 |
YKR062W |
TFIIE small subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FYV7 |
YLR068W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NDE2 |
YDL085W |
Mitochondrial external NADH dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MKC7 |
YDR144C |
GPI-anchored aspartyl protease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MMS2 |
YGL087C |
Ubiquitin-conjugating enzyme variant |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TCD2 |
YKL027W |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NGL1 |
YOL042W |
Putative endonuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CEX1 |
YOR112W |
Component of nuclear aminoacylation-dependent tRNA export pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TIP41 |
YPR040W |
Tap42p-interacting protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CHS3 |
YBR023C |
Chitin synthase III |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
SKT5 |
YBL061C |
Activator of Chs3p (chitin synthase III) during vegetative growth |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MBF1 |
YOR298C-A |
Transcriptional coactivator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DOA4 |
YDR069C |
Ubiquitin hydrolase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CYM1 |
YDR430C |
Lysine-specific metalloprotease of the pitrilysin family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GTA1 |
YEL043W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CNB1 |
YKL190W |
Calcineurin B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KAP95 |
YLR347C |
Karyopherin beta |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UFE1 |
YOR075W |
t-SNARE protein required for retrograde vesicular traffic |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SMT1 |
YJL147C |
Translational repressor of the mitochondrial ATP6/8 mRNA |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ENT4 |
YLL038C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ANY1 |
YMR010W |
Protein involved in phospholipid flippase function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
ASR1 |
YPR093C |
Ubiquitin ligase that modifies and regulates RNA Pol II |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-MS |
HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PIL1 |
YGR086C |
Eisosome core component |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PSD2 |
YGR170W |
Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
HHT1 |
YBR010W |
Histone H3 |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
MSN5 |
YDR335W |
Karyopherin |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SYM1 |
YLR251W |
Protein required for ethanol metabolism |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FMS1 |
YMR020W |
Polyamine oxidase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HLJ1 |
YMR161W |
Co-chaperone for Hsp40p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PDR12 |
YPL058C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SIL1 |
YOL031C |
Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
OST5 |
YGL226C-A |
Zeta subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
ERP1 |
YAR002C-A |
Member of the p24 family involved in ER to Golgi transport |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
EMP65 |
YER140W |
Integral membrane protein of the ER |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
SLP1 |
YOR154W |
Glycosylated integral ER membrane protein of unknown function |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
SPC2 |
YML055W |
Subunit of signal peptidase complex |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
SRB8 |
YCR081W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
HMG1 |
YML075C |
HMG-CoA reductase |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
LAT1 |
YNL071W |
Dihydrolipoamide acetyltransferase component (E2) of the PDC |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YIP1 |
YGR172C |
Integral membrane protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RET3 |
YPL010W |
Zeta subunit of the coatomer complex (COPI) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TSC3 |
YBR058C-A |
Protein that stimulates the activity of serine palmitoyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TYE7 |
YOR344C |
Serine-rich protein that contains a bHLH DNA binding motif |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CAD1 |
YDR423C |
AP-1-like basic leucine zipper (bZIP) transcriptional activator |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Positive Genetic |
ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APC2 |
YLR127C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
APL2 |
YKL135C |
Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
APL5 |
YPL195W |
Delta adaptin-like subunit of the clathrin associated protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASF1 |
YJL115W |
Nucleosome assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADE57 |
YGL234W |
Bifunctional enzyme of 'de novo' purine nucleotide pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BGL2 |
YGR282C |
Endo-beta-1,3-glucanase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
AHP1 |
YLR109W |
Thiol-specific peroxiredoxin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARO4 |
YBR249C |
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APA1 |
YCL050C |
AP4A phosphorylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP5 |
YDR298C |
Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BIT2 |
YBR270C |
Subunit of TORC2 membrane-associated complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN2 |
YDR283C |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSC7 |
YHR039C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YAR010C |
YAR010C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR415C |
YDR415C |
Putative aminopeptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDP1 |
YDL066W |
Mitochondrial NADP-specific isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YGR054W |
YGR054W |
Eukaryotic initiation factor eIF2A |
physical |
1 |
1 |
1 |
PCA |
CDC19 |
YAL038W |
Pyruvate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URA2 |
YJL130C |
Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRH1 |
YDR033W |
Protein that localizes primarily to the plasma membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HXT3 |
YDR345C |
Low affinity glucose transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAS1 |
YKL182W |
Beta subunit of fatty acid synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP10 |
YJL109C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NET1 |
YJL076W |
Core subunit of the RENT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YHR214C-B |
YHR214C-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPR158W-B |
YPR158W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YML045W |
YML045W |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YLR419W |
YLR419W |
Putative helicase with limited sequence similarity to human Rb protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EFT1 |
YOR133W |
Elongation factor 2 (EF-2), also encoded by EFT2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOP2 |
YNL088W |
Topoisomerase II |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLU1 |
YMR012W |
Subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FUN12 |
YAL035W |
Translation initiation factor eIF5B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP12 |
YPL012W |
Protein required for export of the ribosomal subunits |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAB6 |
YML117W |
Putative RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA135 |
YPR010C |
RNA polymerase I second largest subunit A135 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRE33 |
YNL132W |
Acetyltransferase required for biogenesis of small ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIS1 |
YBR084W |
Mitochondrial C1-tetrahydrofolate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RNR1 |
YER070W |
Major isoform of large subunit of ribonucleotide-diphosphate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
DEF1 |
YKL054C |
RNAPII degradation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HRK1 |
YOR267C |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THS1 |
YIL078W |
Threonyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THS1 |
YIL078W |
Threonyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOC2 |
YOR206W |
Protein involved in ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP4 |
YPL043W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSD1 |
YDR293C |
Translational repressor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMY2 |
YBR172C |
GYF domain protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP4 |
YDR324C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP4 |
YDR324C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESF1 |
YDR365C |
Nucleolar protein involved in pre-rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ESF1 |
YDR365C |
Nucleolar protein involved in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF6 |
YDR496C |
Pumilio-homology domain protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAA4 |
YMR246W |
Long chain fatty acyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSS116 |
YDR194C |
Mitochondrial transcription elongation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOG1 |
YPL093W |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSG1 |
YGL099W |
Putative GTPase involved in 60S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSG1 |
YGL099W |
Putative GTPase involved in 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOT5 |
YPR072W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAB1 |
YER165W |
Poly(A) binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV2 |
YMR108W |
Acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRN1 |
YPL184C |
RNA-binding protein that may be involved in translational regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP9 |
YHR196W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP68 |
YPL243W |
Core component of the signal recognition particle (SRP) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP68 |
YPL243W |
Core component of the signal recognition particle (SRP) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAE1 |
YKL029C |
Mitochondrial malic enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP40 |
YKR092C |
Nucleolar serine-rich protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP72 |
YPL210C |
Core component of the signal recognition particle (SRP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP72 |
YPL210C |
Core component of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSZ1 |
YHR064C |
Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDC1 |
YLR044C |
Major of three pyruvate decarboxylase isozymes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPR3 |
YML074C |
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMD4 |
YML056C |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FRS2 |
YFL022C |
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GUA1 |
YMR217W |
GMP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PGI1 |
YBR196C |
Glycolytic enzyme phosphoglucose isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DIG1 |
YPL049C |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DIG1 |
YPL049C |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPR4 |
YLR449W |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP13 |
YNL175C |
Nucleolar protein found in preribosomal complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PGK1 |
YCR012W |
3-phosphoglycerate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAH1 |
YER043C |
S-adenosyl-L-homocysteine hydrolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GND1 |
YHR183W |
6-phosphogluconate dehydrogenase (decarboxylating) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF1 |
YKR059W |
Translation initiation factor eIF4A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF2 |
YJL138C |
Translation initiation factor eIF4A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RNQ1 |
YCL028W |
[PIN(+)] prion |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SER1 |
YOR184W |
3-phosphoserine aminotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRO1 |
YDR300C |
Gamma-glutamyl kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRO1 |
YDR300C |
Gamma-glutamyl kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RBG1 |
YAL036C |
Member of the DRG family of GTP-binding proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FBA1 |
YKL060C |
Fructose 1,6-bisphosphate aldolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAK16 |
YAL025C |
Essential nuclear protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THR1 |
YHR025W |
Homoserine kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSA1 |
YDL055C |
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CYS3 |
YAL012W |
Cystathionine gamma-lyase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CHA1 |
YCL064C |
Catabolic L-serine (L-threonine) deaminase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TDH2 |
YJR009C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA6 |
YLR447C |
Subunit d of the V0 integral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRX1 |
YOL077C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRS3 |
YHL011C |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IMP4 |
YNL075W |
Component of the SSU processome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SOL2 |
YCR073W-A |
Protein with a possible role in tRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SOL1 |
YNR034W |
Protein with a possible role in tRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS4A |
YJR145C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS4A |
YJR145C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRO3 |
YER023W |
Delta 1-pyrroline-5-carboxylate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPE3 |
YPR069C |
Spermidine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMS1 |
YLR003C |
Putative subunit of the 90S preribosome processome complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URA1 |
YKL216W |
Dihydroorotate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MGM101 |
YJR144W |
Protein with a role in mitochondrial DNA recombinational repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF35 |
YDR429C |
eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PET9 |
YBL030C |
Major ADP/ATP carrier of the mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC13 |
YLR208W |
Structural component of 3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL13B |
YMR142C |
Ribosomal 60S subunit protein L13B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL2B |
YIL018W |
Ribosomal 60S subunit protein L2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8B |
YER102W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS5 |
YJR123W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPM1 |
YKL152C |
Tetrameric phosphoglycerate mutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC53 |
YFL045C |
Phosphomannomutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PYP1 |
YNL010W |
Sugar alcohol phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUP2 |
YGR253C |
Alpha 5 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GRX4 |
YER174C |
Glutathione-dependent oxidoreductase and glutathione S-transferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GRX3 |
YDR098C |
Glutathione-dependent oxidoreductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL9A |
YGL147C |
Ribosomal 60S subunit protein L9A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL27A |
YHR010W |
Ribosomal 60S subunit protein L27A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL24A |
YGL031C |
Ribosomal 60S subunit protein L24A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TPI1 |
YDR050C |
Triose phosphate isomerase, abundant glycolytic enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC33 |
YOL139C |
Translation initiation factor eIF4E |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRS1 |
YOR294W |
Essential protein that binds ribosomal protein L11 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA22 |
YJR014W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL19A |
YBR084C-A |
Ribosomal 60S subunit protein L19A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL1B |
YGL135W |
Ribosomal 60S subunit protein L1B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBP4 |
YDL053C |
Pbp1p binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBP4 |
YDL053C |
Pbp1p binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PNC1 |
YGL037C |
Nicotinamidase that converts nicotinamide to nicotinic acid |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FUR1 |
YHR128W |
Uracil phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRE5 |
YMR314W |
Alpha 6 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTB1 |
YDR224C |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTB2 |
YBL002W |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS9B |
YBR189W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSM12 |
YHR121W |
Protein of unknown function that may function in RNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL17A |
YKL180W |
Ribosomal 60S subunit protein L17A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAA1 |
YDR071C |
Polyamine acetyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSM4 |
YER112W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA19 |
YKL056C |
Protein that associates with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC36 |
YDL165W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC36 |
YDL165W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IMP3 |
YHR148W |
Component of the SSU processome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL18A |
YOL120C |
Ribosomal 60S subunit protein L18A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL18B |
YNL301C |
Ribosomal 60S subunit protein L18B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL12B |
YDR418W |
Ribosomal 60S subunit protein L12B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL12A |
YEL054C |
Ribosomal 60S subunit protein L12A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL20A |
YMR242C |
Ribosomal 60S subunit protein L20A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL20B |
YOR312C |
Ribosomal 60S subunit protein L20B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TSA1 |
YML028W |
Thioredoxin peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL21A |
YBR191W |
Ribosomal 60S subunit protein L21A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL11A |
YPR102C |
Ribosomal 60S subunit protein L11A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL11B |
YGR085C |
Ribosomal 60S subunit protein L11B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HCH1 |
YNL281W |
Heat shock protein regulator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL24B |
YGR148C |
Ribosomal 60S subunit protein L24B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAR1 |
YPL218W |
ARF family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP14 |
YDL092W |
Signal recognition particle (SRP) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NHP2 |
YDL208W |
Protein related to mammalian high mobility group (HMG) proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL14B |
YHL001W |
Ribosomal 60S subunit protein L14B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MNP1 |
YGL068W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS17B |
YDR447C |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS24B |
YIL069C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS18B |
YML026C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS14B |
YJL191W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL32 |
YBL092W |
Ribosomal 60S subunit protein L32 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS23B |
YPR132W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
MLC1 |
YGL106W |
Essential light chain for Myo1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTA1 |
YDR225W |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
HTA2 |
YBL003C |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL34B |
YIL052C |
Ribosomal 60S subunit protein L34B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL34A |
YER056C-A |
Ribosomal 60S subunit protein L34A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS26A |
YGL189C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS26B |
YER131W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA12 |
YJR063W |
RNA polymerase I subunit A12.2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL36B |
YPL249C-A |
Ribosomal 60S subunit protein L36B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL33A |
YPL143W |
Ribosomal 60S subunit protein L33A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31B |
YLR406C |
Ribosomal 60S subunit protein L31B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MMF1 |
YIL051C |
Mitochondrial protein required for transamination of isoleucine |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22B |
YLR367W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS21A |
YKR057W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNU13 |
YEL026W |
RNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL43B |
YJR094W-A |
Ribosomal 60S subunit protein L43B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS30B |
YOR182C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS25B |
YLR333C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS25B |
YLR333C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS25A |
YGR027C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL39 |
YJL189W |
Ribosomal 60S subunit protein L39 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL38 |
YLR325C |
Ribosomal 60S subunit protein L38 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRI2 |
YOL117W |
Subunit of the COP9 signalosome (CSN) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMB1 |
YER029C |
Core Sm protein Sm B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MUD1 |
YBR119W |
U1 snRNP A protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAM8 |
YHR086W |
RNA binding protein, component of the U1 snRNP protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSL5 |
YLR116W |
Component of commitment complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
genetic |
1 |
1 |
1 |
Positive Genetic |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDP3 |
YLR455W |
Component of the NuA3b histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MTQ2 |
YDR140W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPL6 |
YMR091C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTT106 |
YNL206C |
Histone chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWD2 |
YKL018W |
Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEX2 |
YNL238W |
Kexin, a subtilisin-like protease (proprotein convertase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD3 |
YER171W |
5' to 3' DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC12 |
YLR306W |
Enzyme that mediates the conjugation of Rub1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
RDH54 |
YBR073W |
DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELC1 |
YPL046C |
Elongin C, conserved among eukaryotes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUS81 |
YDR386W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC58 |
YLR033W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC7 |
YMR022W |
Ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YML119W |
YML119W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Positive Genetic |
MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NHP6A |
YPR052C |
High-mobility group (HMG) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP12 |
YJL197W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
UFD4 |
YKL010C |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SQS1 |
YNL224C |
Protein that stimulates the ATPase and helicase activities of Prp43p |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCW22 |
YDR134C |
Cell wall protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
1 |
1 |
1 |
Positive Genetic |
IOC2 |
YLR095C |
Subunit of the Isw1b complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SKI8 |
YGL213C |
Ski complex component and WD-repeat protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DUT1 |
YBR252W |
Deoxyuridine triphosphate diphosphatase (dUTPase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GDA1 |
YEL042W |
Guanosine diphosphatase located in the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIO2 |
YNL207W |
Essential serine kinase involved in the processing of 20S pre-rRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
THO2 |
YNL139C |
Subunit of the THO complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPC53 |
YDL150W |
RNA polymerase III subunit C53 |
genetic |
1 |
1 |
1 |
Negative Genetic |
YFH1 |
YDL120W |
Mitochondrial matrix iron chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSY1 |
YDR160W |
Component of the SPS plasma membrane amino acid sensor system |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
1 |
1 |
1 |
Positive Genetic |
SFI1 |
YLL003W |
Centrin (Cdc31p)-binding protein required for SPB duplication |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PIB1 |
YDR313C |
RING-type ubiquitin ligase of the endosomal and vacuolar membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFA5 |
YDR459C |
Palmitoyltransferase with autoacylation activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
STP1 |
YDR463W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
KRE28 |
YDR532C |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCY2 |
YER056C |
Purine-cytosine permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMN3 |
YER113C |
Protein with a role in cellular adhesion and filamentous growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSH4 |
YFL003C |
Protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDL1 |
YIL167W |
Blocked reading frame otherwise encoding L-serine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESL1 |
YIL151C |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IML2 |
YJL082W |
Protein required for clearance of inclusion bodies |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL095C |
YNL095C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD18 |
YCR066W |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAL80 |
YKR034W |
Negative regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
USV1 |
YPL230W |
Putative transcription factor containing a C2H2 zinc finger |
genetic |
1 |
1 |
1 |
Positive Genetic |
OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIN1 |
YOR349W |
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LYS14 |
YDR034C |
Transcriptional activator involved in regulating lysine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
FLO8 |
YER109C |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEL2 |
YDR266C |
RING finger ubiquitin ligase (E3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPI1 |
YIL119C |
Transcription factor, allelic differences between S288C and Sigma1278b |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIG3 |
YER028C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
OAF1 |
YAL051W |
Oleate-activated transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPH1 |
YER169W |
JmjC domain-containing histone demethylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IES4 |
YOR189W |
Component of the INO80 chromatiin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
1 |
1 |
1 |
Positive Genetic |
OPY1 |
YBR129C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
FEN2 |
YCR028C |
Plasma membrane H+-pantothenate symporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOP1 |
YDR141C |
Protein involved in vesicular transport at trans-Golgi network (TGN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEP7 |
YDR323C |
Adaptor protein involved in vesicle-mediated vacuolar protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB7 |
YDR404C |
RNA polymerase II subunit B16 |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDJ1 |
YFL016C |
Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
1 |
1 |
1 |
Negative Genetic |
UGA1 |
YGR019W |
Gamma-aminobutyrate (GABA) transaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA22 |
YHR060W |
Protein that is required for vacuolar H+-ATPase (V-ATPase) function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCJ1 |
YMR214W |
One of several homologs of bacterial chaperone DnaJ |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIP3 |
YNL044W |
Protein localized to COPII vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGR2 |
YPL098C |
Subunit of the TIM23 translocase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SYH1 |
YPL105C |
Protein of unknown function that influences nuclear pore distribution |
genetic |
1 |
1 |
1 |
Positive Genetic |
EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TTI2 |
YJR136C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
NPR1 |
YNL183C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPK1 |
YKL126W |
S/T protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DSL1 |
YNL258C |
Peripheral membrane protein needed for Golgi-to-ER retrograde traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIB5 |
YBR256C |
Riboflavin synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HEM13 |
YDR044W |
Coproporphyrinogen III oxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
CAB4 |
YGR277C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Positive Genetic |
NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBA1 |
YKL210W |
Ubiquitin activating enzyme (E1) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
CWC24 |
YLR323C |
General splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Positive Genetic |
DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Positive Genetic |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAM1 |
YDL090C |
Beta subunit of the CAAX farnesyltransferase (FTase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SFA1 |
YDL168W |
Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUD25 |
YER014C-A |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Positive Genetic |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YGL114W |
YGL114W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YGR122W |
YGR122W |
Protein that may be involved in pH regulation |
genetic |
1 |
1 |
1 |
Positive Genetic |
QCR9 |
YGR183C |
Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Positive Genetic |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
COA3 |
YJL062W-A |
Mitochondrial protein required for cytochrome c oxidase assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
QCR8 |
YJL166W |
Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJR115W |
YJR115W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
HMS2 |
YJR147W |
Protein with similarity to heat shock transcription factors |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEG2 |
YKL105C |
Eisosome component |
genetic |
1 |
1 |
1 |
Positive Genetic |
KTI12 |
YKL110C |
Protein that plays a role in modification of tRNA wobble nucleosides |
genetic |
1 |
1 |
1 |
Positive Genetic |
COX17 |
YLL009C |
Copper metallochaperone that transfers copper to Sco1p and Cox11p |
genetic |
1 |
1 |
1 |
Positive Genetic |
CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSS1 |
YMR023C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YSF3 |
YNL138W-A |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPP1A |
YDL081C |
Ribosomal stalk protein P1 alpha |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VTC3 |
YPL019C |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUV3 |
YPL029W |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
INA17 |
YPL099C |
F1F0 ATPase synthase peripheral stalk assembly factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
ISU1 |
YPL135W |
Conserved protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Positive Genetic |
COA2 |
YPL189C-A |
Cytochrome oxidase assembly factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HOB2 |
YPR117W |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP45 |
YAL032C |
Protein required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
ILS1 |
YBL076C |
Cytoplasmic isoleucine-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHS2 |
YBR038W |
Chitin synthase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBN1 |
YCL052C |
Component of glycosylphosphatidylinositol-mannosyltransferase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP10 |
YDL031W |
Putative ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD6 |
YDR211W |
Catalytic epsilon subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEM1 |
YDR232W |
5-aminolevulinate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR341C |
YDR341C |
Arginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI17 |
YDR434W |
Transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS31 |
YDR472W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT1 |
YFL038C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA15 |
YGL044C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSA1 |
YGL111W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VHT1 |
YGR065C |
High-affinity plasma membrane H+-biotin (vitamin H) symporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD2 |
YGR083C |
Delta subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTI1 |
YGR156W |
Essential component of CPF (cleavage and polyadenylation factor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MES1 |
YGR264C |
Methionyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFA1 |
YKL028W |
TFIIE large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAE1 |
YKR038C |
Highly conserved ATPase of HSP70/DnaK family |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRC3 |
YLL035W |
Polynucleotide kinase present on rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMT1 |
YLR195C |
N-myristoyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC123 |
YLR215C |
Assembly factor for the eIF2 translation initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUS1 |
YMR240C |
Protein required for assembly of U2 snRNP into the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRN9 |
YMR270C |
Protein involved in promoting high level transcription of rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOB1 |
YOR056C |
Protein involved in proteasomal and 40S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTR10 |
YOR160W |
Nuclear import receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN4 |
YOR168W |
Glutamine tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
1 |
1 |
1 |
Negative Genetic |
IDI1 |
YPL117C |
Isopentenyl diphosphate:dimethylallyl diphosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB2 |
YPL122C |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP46 |
YPL151C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAH18 |
YPR048W |
Conserved NAPDH-dependent diflavin reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB4 |
YPR056W |
Subunit of TFIIH complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIP20 |
YGL145W |
Peripheral membrane protein required for COPI vesicle fusion to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI12 |
YMR281W |
ER membrane protein involved in the second step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRP1 |
YOL123W |
Subunit of cleavage factor I |
genetic |
1 |
1 |
1 |
Negative Genetic |
LDS1 |
YAL018C |
Protein Involved in spore wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCS22 |
YBL091C-A |
Protein involved in regulation of phospholipid metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR096W |
YBR096W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPC1 |
YBR183W |
Alkaline ceramidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERT1 |
YBR239C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL32 |
YCR003W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
TVS1 |
YCR061W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSK22 |
YCR073C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
SND1 |
YDR186C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
REF2 |
YDR195W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YSP2 |
YDR326C |
Sterol-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIZ1 |
YDR409W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GNP1 |
YDR508C |
Broad specificity amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPS2 |
YDR522C |
Protein expressed during sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPA1 |
YER049W |
Prolyl hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAP123 |
YER110C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
YFR006W |
YFR006W |
Putative X-Pro aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF4 |
YGL014W |
Member of the PUF protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPC1 |
YGL080W |
Highly conserved subunit of mitochondrial pyruvate carrier (MPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS45 |
YGL095C |
Protein of the Sec1p/Munc-18 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPG1 |
YGL121C |
Proposed gamma subunit of the heterotrimeric G protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YRB30 |
YGL164C |
RanGTP-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOC1 |
YGL240W |
Processivity factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR016W |
YGR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI4 |
YGR144W |
Thiazole synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPC1 |
YGR149W |
Glycerophosphocholine acyltransferase (GPCAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTS3 |
YGR161C |
Putative component of the protein phosphatase type 2A complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEL2 |
YGR238C |
Protein that negatively regulates mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAY1 |
YGR263C |
Sterol deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LEU5 |
YHR002W |
Mitochondrial carrier protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
STP2 |
YHR006W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
FYV4 |
YHR059W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRP1 |
YHR146W |
Protein that binds to cruciform DNA structures |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMO1 |
YHR176W |
Flavin-containing monooxygenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAS2 |
YIL007C |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MHP1 |
YJL042W |
Microtubule-associated protein involved in microtubule organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
IKS1 |
YJL057C |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAX4 |
YJL083W |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO1 |
YJL153C |
Inositol-3-phosphate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MLO127 |
YJR039W |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIS2 |
YKR072C |
Negative regulatory subunit of protein phosphatase 1 (Ppz1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRE8 |
YLR047C |
Protein with sequence similarity to iron/copper reductases |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNL2 |
YLR057W |
Putative mannosidase involved in ER-associated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR159W |
YLR159W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIC1 |
YLR348C |
Mitochondrial dicarboxylate carrier |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCW14 |
YLR390W-A |
Covalently linked cell wall glycoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CST9 |
YLR394W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRM12 |
YML005W |
S-adenosylmethionine-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC21 |
YMR073C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL24 |
YMR193W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAS3 |
YMR215W |
Putative 1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GOT1 |
YMR292W |
Homodimeric protein that is packaged into COPII vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
WSC2 |
YNL283C |
Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCR1 |
YBR005W |
Plasma membrane (PM) ubiquitin ligase-substrate adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM8 |
YBR076W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR284W |
YBR284W |
Putative metallo-dependent hydrolase superfamily protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YFL051C |
YFL051C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUP1 |
YGR055W |
High affinity methionine permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
HPM1 |
YIL110W |
AdoMet-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN5 |
YJL186W |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTO3 |
YMR251W |
Omega class glutathione transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIT1 |
YMR283C |
Initiator methionine 2'-O-ribosyl phosphate transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TGL3 |
YMR313C |
Bifunctional triacylglycerol lipase and LPE acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPK9 |
YOR291W |
Vacuolar protein with a possible role in sequestering heavy metals |
genetic |
1 |
1 |
1 |
Negative Genetic |
FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Negative Genetic |
THP3 |
YPR045C |
Protein that may have a role in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRL1 |
YPR079W |
Membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL164W-A |
YOL164W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB4 |
YOR171C |
Sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI72 |
YOR192C |
Transporter of thiamine or related compound |
genetic |
1 |
1 |
1 |
Negative Genetic |
RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR296W |
YOR296W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNX3 |
YOR357C |
Sorting nexin for late-Golgi enzymes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMA1 |
YPL027W |
Protein of unknown function involved in prospore membrane assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERI1 |
YPL096C-A |
Endoplasmic reticulum membrane protein that binds and inhibits Ras2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT10 |
YPL183C |
WD40 domain-containing protein involved in endosomal recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI21 |
YPL258C |
Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUT2 |
YPR009W |
Zn2Cys6 family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
LDB16 |
YCL005W |
Protein involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
PET127 |
YOR017W |
Protein with a role in 5'-end processing of mitochondrial RNAs |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
KAP122 |
YGL016W |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
HGH1 |
YGR187C |
Chaperone protein for translation factor eEF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Positive Genetic |
STT4 |
YLR305C |
Phosphatidylinositol-4-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC60 |
YPL160W |
Cytosolic leucyl tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAT4 |
YCR008W |
Ser/Thr protein kinase involved in salt tolerance, nutrient response |
genetic |
1 |
1 |
1 |
Negative Genetic |
STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADY4 |
YLR227C |
Structural component of the meiotic outer plaque |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG5 |
YPL227C |
UDP-glucose:dolichyl-phosphate glucosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATM1 |
YMR301C |
Mitochondrial inner membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP18 |
YML081C-A |
Subunit of the mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASG7 |
YJL170C |
Protein that regulates signaling from G protein beta subunit Ste4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM45 |
YPR004C |
Putative ortholog of mammalian ETF-alpha |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARI1 |
YGL157W |
NADPH-dependent aldehyde reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATP12 |
YJL180C |
Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ANR2 |
YKL047W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AAD4 |
YDL243C |
Putative aryl-alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASP1 |
YDR321W |
Cytosolic L-asparaginase, involved in asparagine catabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AST2 |
YER101C |
Lipid raft associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATR2 |
YMR279C |
Putative boron transporter involved in boron efflux and resistance |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADY2 |
YCR010C |
Acetate transporter required for normal sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCD1 |
YHR040W |
Essential protein required for the accumulation of box C/D snoRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
AAT1 |
YKL106W |
Mitochondrial aspartate aminotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |