| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
8 |
3 |
6 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
7 |
3 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
7 |
2 |
4 |
Synthetic Rescue, Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
6 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CBK1 |
YNL161W |
Serine/threonine protein kinase of the the RAM signaling network |
genetic |
6 |
4 |
5 |
Synthetic Rescue, Synthetic Rescue, Dosage Lethality, Synthetic Growth Defect, Dosage Lethality, Dosage Growth Defect |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
genetic |
6 |
3 |
5 |
Phenotypic Enhancement, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
6 |
2 |
5 |
Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
6 |
2 |
5 |
Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
6 |
2 |
5 |
Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
5 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
5 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CBK1 |
YNL161W |
Serine/threonine protein kinase of the the RAM signaling network |
physical |
5 |
4 |
4 |
Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Biochemical Activity, Reconstituted Complex |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
5 |
3 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic |
| JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
5 |
2 |
4 |
Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CTS1 |
YLR286C |
Endochitinase |
physical |
5 |
3 |
3 |
Affinity Capture-RNA, Affinity Capture-Luminescence, Two-hybrid, Affinity Capture-RNA, Affinity Capture-RNA |
| RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
4 |
2 |
4 |
Synthetic Rescue, Negative Genetic, Negative Genetic, Negative Genetic |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
genetic |
4 |
3 |
3 |
Dosage Rescue, Synthetic Lethality, Synthetic Rescue, Synthetic Lethality |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Negative Genetic, Dosage Rescue, Negative Genetic |
| UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
genetic |
4 |
2 |
3 |
Positive Genetic, Positive Genetic, Phenotypic Suppression, Positive Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
4 |
2 |
3 |
Synthetic Rescue, Positive Genetic, Synthetic Rescue, Synthetic Rescue |
| DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| HRK1 |
YOR267C |
Protein kinase |
genetic |
4 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ATG21 |
YPL100W |
Phosphoinositide binding protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| DYN3 |
YMR299C |
Dynein light intermediate chain (LIC) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SOG2 |
YOR353C |
Key component of the RAM signaling network |
genetic |
4 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
| CDC42 |
YLR229C |
Small rho-like GTPase |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic |
| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
3 |
3 |
3 |
Dosage Rescue, Synthetic Lethality, Negative Genetic |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
3 |
3 |
3 |
Phenotypic Suppression, Dosage Rescue, Negative Genetic |
| YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Positive Genetic, Positive Genetic |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Positive Genetic |
| CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
3 |
2 |
3 |
Positive Genetic, Phenotypic Suppression, Positive Genetic |
| CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SUN4 |
YNL066W |
Cell wall protein related to glucanases localized in birth scars |
physical |
3 |
1 |
3 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CAK1 |
YFL029C |
Cyclin-dependent kinase-activating kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CGR1 |
YGL029W |
Protein involved in nucleolar integrity and processing of pre-rRNA |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PFA4 |
YOL003C |
Palmitoyltransferase with autoacylation activity |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
3 |
2 |
Synthetic Haploinsufficiency, Positive Genetic, Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
3 |
3 |
2 |
Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect |
| PAB1 |
YER165W |
Poly(A) binding protein |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Co-fractionation |
| ZRG8 |
YER033C |
Protein of unknown function |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
2 |
2 |
Dosage Rescue, Negative Genetic, Negative Genetic |
| SIM1 |
YIL123W |
Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) |
physical |
3 |
2 |
2 |
Affinity Capture-RNA, Affinity Capture-Luminescence, Affinity Capture-RNA |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| UIP5 |
YKR044W |
Protein of unknown function that interacts with Ulp1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| YME2 |
YMR302C |
Integral inner mitochondrial membrane protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ZRG17 |
YNR039C |
Endoplasmic reticulum zinc transporter |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TOP1 |
YOL006C |
Topoisomerase I |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| APL5 |
YPL195W |
Delta adaptin-like subunit of the clathrin associated protein complex |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SKT5 |
YBL061C |
Activator of Chs3p (chitin synthase III) during vegetative growth |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| EXG1 |
YLR300W |
Major exo-1,3-beta-glucanase of the cell wall |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| ERV41 |
YML067C |
Protein localized to COPII-coated vesicles |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DPC29 |
YGR021W |
Putative mitochondrial protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ALG5 |
YPL227C |
UDP-glucose:dolichyl-phosphate glucosyltransferase |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FRK1 |
YPL141C |
Protein kinase of unknown cellular role |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RUP1 |
YOR138C |
Protein that regulates ubiquitination of Rsp5p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CHS6 |
YJL099W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RSA3 |
YLR221C |
Protein with a likely role in ribosomal maturation |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CHS7 |
YHR142W |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARO7 |
YPR060C |
Chorismate mutase |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| ALG8 |
YOR067C |
Glucosyl transferase |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
2 |
2 |
2 |
PCA, Affinity Capture-RNA |
| SSD1 |
YDR293C |
Translational repressor |
physical |
2 |
2 |
2 |
Affinity Capture-MS, PCA |
| UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
physical |
2 |
2 |
2 |
Affinity Capture-Luminescence, Affinity Capture-RNA |
| TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| YPT1 |
YFL038C |
Rab family GTPase |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
2 |
2 |
2 |
Affinity Capture-RNA, Affinity Capture-MS |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Rescue |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
2 |
2 |
2 |
PCA, Affinity Capture-MS |
| BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
2 |
2 |
2 |
PCA, Affinity Capture-RNA |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-RNA |
| CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-RNA |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-RNA |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
| AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
2 |
2 |
2 |
PCA, Affinity Capture-RNA |
| RLM1 |
YPL089C |
MADS-box transcription factor |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Enhancement |
| CAB1 |
YDR531W |
Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| GIS1 |
YDR096W |
Histone demethylase and transcription factor |
physical |
2 |
2 |
2 |
Affinity Capture-RNA, Affinity Capture-MS |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
2 |
2 |
2 |
Dosage Rescue, Positive Genetic |
| SMP3 |
YOR149C |
Alpha 1,2-mannosyltransferase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Positive Genetic |
| PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| AXL2 |
YIL140W |
Integral plasma membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAP190 |
YKR028W |
Protein that forms a complex with the Sit4p protein phosphatase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PSY2 |
YNL201C |
Subunit of protein phosphatase PP4 complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| XPT1 |
YJR133W |
Xanthine-guanine phosphoribosyl transferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSP120 |
YLR250W |
Protein packaged into COPII vesicles for ER to Golgi trafficking |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBC12 |
YLR306W |
Enzyme that mediates the conjugation of Rub1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWC7 |
YLR385C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YMR295C |
YMR295C |
Protein of unknown function that associates with ribosomes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YNL108C |
YNL108C |
Protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VHS3 |
YOR054C |
Negative regulatory subunit of protein phosphatase 1 Ppz1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TKL1 |
YPR074C |
Transketolase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MRPL39 |
YML009C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ATG3 |
YNR007C |
E2-like enzyme |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SKN1 |
YGR143W |
Protein involved in sphingolipid biosynthesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PSY4 |
YBL046W |
Regulatory subunit of protein phosphatase PP4 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| FAR8 |
YMR029C |
Protein involved in recovery from arrest in response to pheromone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CSR2 |
YPR030W |
Nuclear ubiquitin protein ligase binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
| GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PTC5 |
YOR090C |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAC11 |
YDR488C |
Dynein intermediate chain, microtubule motor protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUD32 |
YGR262C |
Protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GPG1 |
YGL121C |
Proposed gamma subunit of the heterotrimeric G protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GIS4 |
YML006C |
CAAX box containing protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSG5 |
YNL053W |
Dual-specificity protein phosphatase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PEX15 |
YOL044W |
Tail-anchored type II integral peroxisomal membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DCK1 |
YLR422W |
Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CRP1 |
YHR146W |
Protein that binds to cruciform DNA structures |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HSP150 |
YJL159W |
O-mannosylated heat shock protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| BUD6 |
YLR319C |
Actin- and formin-interacting protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CAT8 |
YMR280C |
Zinc cluster transcriptional activator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CHS3 |
YBR023C |
Chitin synthase III |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GAD1 |
YMR250W |
Glutamate decarboxylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MIX17 |
YMR002W |
Mitochondrial intermembrane space protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| CPS1 |
YJL172W |
Vacuolar carboxypeptidase S |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ANT1 |
YPR128C |
Peroxisomal adenine nucleotide transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FAT1 |
YBR041W |
Very long chain fatty acyl-CoA synthetase and fatty acid transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SOK1 |
YDR006C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IMP21 |
YIL154C |
Transcriptional activator involved in maintenance of ion homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPP1A |
YDL081C |
Ribosomal stalk protein P1 alpha |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MRS2 |
YOR334W |
Mitochondrial inner membrane Mg(2+) channel |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPE1 |
YJL121C |
D-ribulose-5-phosphate 3-epimerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MTC2 |
YKL098W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| APS3 |
YJL024C |
Small subunit of the clathrin-associated adaptor complex AP-3 |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| GSH2 |
YOL049W |
Glutathione synthetase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| DSD1 |
YGL196W |
D-serine dehydratase (aka D-serine ammonia-lyase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MFM1 |
YPL060W |
Mitochondrial inner membrane magnesium transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LRE1 |
YCL051W |
Protein involved in control of cell wall structure and stress response |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| DBR1 |
YKL149C |
RNA lariat debranching enzyme |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PPM1 |
YDR435C |
Carboxyl methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RSO55 |
YLR281C |
Mitochondrial protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PRM6 |
YML047C |
Potassium transporter that mediates K+ influx |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Reconstituted Complex |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Growth Defect |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| SWC3 |
YAL011W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YKL033W-A |
YKL033W-A |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| YMD8 |
YML038C |
Putative nucleotide sugar transporter |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FAP1 |
YNL023C |
Protein that binds to Fpr1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HTB1 |
YDR224C |
Histone H2B |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| PSH1 |
YOL054W |
E3 ubiquitin ligase targeting centromere-binding protein Cse4p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SGM1 |
YJR134C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HUL4 |
YJR036C |
Protein with similarity to hect domain E3 ubiquitin-protein ligases |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ASE1 |
YOR058C |
Mitotic spindle midzone-localized microtubule bundling protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BIO2 |
YGR286C |
Biotin synthase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GCD14 |
YJL125C |
Subunit of tRNA (1-methyladenosine) methyltransferase |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| IDP1 |
YDL066W |
Mitochondrial NADP-specific isocitrate dehydrogenase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ARN2 |
YHL047C |
Transporter |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| IRC5 |
YFR038W |
Putative ATPase containing the DEAD/H helicase-related sequence motif |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MCP1 |
YOR228C |
Mitochondrial protein of unknown function involved in lipid homeostas |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| GAT3 |
YLR013W |
Protein containing GATA family zinc finger motifs |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| NCA2 |
YPR155C |
Protein that regulates expression of Fo-F1 ATP synthase subunits |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SOL4 |
YGR248W |
6-phosphogluconolactonase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PAU4 |
YLR461W |
Member of the seripauperin multigene family |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
| YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CEF1 |
YMR213W |
Essential splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSF2 |
YJL072C |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP7 |
YGR103W |
Component of several different pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PLB1 |
YMR008C |
Phospholipase B (lysophospholipase) involved in lipid metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| AMN1 |
YBR158W |
Modulator of cell separation and mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RAX2 |
YLR084C |
Protein required for the maintenance of bud site selection |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP4 |
YBR257W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC23 |
YGL128C |
Component of a complex containing Cef1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAP185 |
YJL098W |
Protein that forms a complex with the Sit4p protein phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAP185 |
YJL098W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIS3 |
YOL021C |
Exosome core complex catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRP4 |
YHR069C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP43 |
YCR035C |
Exosome non-catalytic core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC17 |
YJL011C |
RNA polymerase III subunit C17 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC31 |
YNL151C |
RNA polymerase III subunit C31 |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPO31 |
YOR116C |
RNA polymerase III largest subunit C160 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNP1 |
YIL061C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTA1 |
YAL043C |
Subunit of holo-CPF |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP7 |
YER082C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ZRG8 |
YER033C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YGR054W |
YGR054W |
Eukaryotic initiation factor eIF2A |
physical |
1 |
1 |
1 |
PCA |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| URN1 |
YPR152C |
Protein of unknown function containing WW and FF domains |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UGP1 |
YKL035W |
UDP-glucose pyrophosphorylase (UGPase) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| UGP1 |
YKL035W |
UDP-glucose pyrophosphorylase (UGPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
physical |
1 |
1 |
1 |
Two-hybrid |
| YHL009W-A |
YHL009W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Two-hybrid |
| YJL113W |
YJL113W |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Two-hybrid |
| STB6 |
YKL072W |
Protein that binds Sin3p in a two-hybrid assay |
physical |
1 |
1 |
1 |
Two-hybrid |
| UBP2 |
YOR124C |
Ubiquitin-specific protease |
physical |
1 |
1 |
1 |
Two-hybrid |
| ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YKR041W |
YKR041W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TOS8 |
YGL096W |
Homeodomain-containing protein and putative transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| YCH1 |
YGR203W |
Phosphatase with sequence similarity to Mih1p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| YIL060W |
YIL060W |
Mitochondrial protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| VHS1 |
YDR247W |
Cytoplasmic serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TIR1 |
YER011W |
Cell wall mannoprotein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| UTP6 |
YDR449C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TAZ1 |
YPR140W |
Lyso-phosphatidylcholine acyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| YJR120W |
YJR120W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TOS1 |
YBR162C |
Covalently-bound cell wall protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TIR4 |
YOR009W |
Cell wall mannoprotein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TOS2 |
YGR221C |
Protein involved in localization of Cdc24p to the site of bud growth |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| UBC5 |
YDR059C |
Ubiquitin-conjugating enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TAX4 |
YJL083W |
EH domain-containing protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| YPS3 |
YLR121C |
Aspartic protease |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TOD6 |
YBL054W |
PAC motif binding protein involved in rRNA and ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| YBR238C |
YBR238C |
Mitochondrial membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| VID24 |
YBR105C |
GID Complex regulatory subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| WSC2 |
YNL283C |
Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| YBR016W |
YBR016W |
Tail-anchored plasma membrane protein with a conserved CYSTM module |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TVP23 |
YDR084C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TBS1 |
YBR150C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TRM7 |
YBR061C |
2'-O-ribose methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| VID30 |
YGL227W |
Central component of GID Complex, involved in FBPase degradation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TDH1 |
YJL052W |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| YHP1 |
YDR451C |
Homeobox transcriptional repressor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| YNL208W |
YNL208W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC11 |
YOR339C |
Ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER134C |
YER134C |
Magnesium-dependent acid phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| THI13 |
YDL244W |
Protein involved in synthesis of the thiamine precursor HMP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR122W |
YGR122W |
Protein that may be involved in pH regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOM71 |
YHR117W |
Mitochondrial outer membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UPS2 |
YLR168C |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| URA4 |
YLR420W |
Dihydroorotase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCB2 |
YNL087W |
ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL040W |
YNL040W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWM2 |
YNR004W |
Protein with a role in snRNA and snoRNA cap trimethylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ZEO1 |
YOL109W |
Peripheral membrane protein of the plasma membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBC6 |
YER100W |
Ubiquitin-conjugating enzyme involved in ERAD |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA6 |
YLR447C |
Subunit d of the V0 integral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWT21 |
YNL187W |
Protein involved in mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TFC3 |
YAL001C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TFC1 |
YBR123C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VAS1 |
YGR094W |
Mitochondrial and cytoplasmic valyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YGL117W |
YGL117W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TCD2 |
YKL027W |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TRP3 |
YKL211C |
Indole-3-glycerol-phosphate synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YLR278C |
YLR278C |
Zinc-cluster protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPT7 |
YML001W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPQ1 |
YOL092W |
Putative vacuolar membrane transporter for cationic amino acids |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TMH18 |
YPR098C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TYS1 |
YGR185C |
Cytoplasmic tyrosyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP9 |
YHR196W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URA6 |
YKL024C |
Uridylate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP13 |
YLR222C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT4 |
YLR305C |
Phosphatidylinositol-4-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STP1 |
YDR463W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YFR057W |
YFR057W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGK1 |
YGL101W |
5'-deoxynucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL176C |
YGL176C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT32 |
YGL210W |
Rab family GTPase involved in the exocytic pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SVP26 |
YHR181W |
ER exit adaptor for Golgi mannosyltransferases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VID28 |
YIL017C |
GID Complex subunit, serves as adaptor for regulatory subunit Vid24p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKE4 |
YIL023C |
Zinc transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF1 |
YKR059W |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLL032C |
YLL032C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR036C |
YLR036C |
Putative protein predicted to have transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR125W |
YLR125W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC14 |
YLR386W |
Enzyme regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML119W |
YML119W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEP1 |
YNL128W |
PTEN homolog with no demonstrated inositol lipid phosphatase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR105W |
YOR105W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAP1 |
YKL007W |
Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ERG26 |
YGL001C |
C-3 sterol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN2 |
YDR283C |
Protein kinase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HST1 |
YOL068C |
NAD(+)-dependent histone deacetylase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM4 |
YER112W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
PCA |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV4 |
YHR059W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPS18 |
YNL306W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MGM101 |
YJR144W |
Protein with a role in mitochondrial DNA recombinational repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIC96 |
YFR002W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP159 |
YIL115C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| PAP1 |
YKR002W |
Poly(A) polymerase |
physical |
1 |
1 |
1 |
Co-localization |
| PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPH22 |
YDL188C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PRP31 |
YGR091W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP6 |
YBR055C |
Splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NAB6 |
YML117W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IMP4 |
YNL075W |
Component of the SSU processome |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB8 |
YOR224C |
RNA polymerase subunit ABC14.5 |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AMS1 |
YGL156W |
Vacuolar alpha mannosidase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MLH2 |
YLR035C |
Protein involved in mismatch repair and meiotic recombination |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RPC53 |
YDL150W |
RNA polymerase III subunit C53 |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC13 |
YLR208W |
Structural component of 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
PCA |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BGL2 |
YGR282C |
Endo-beta-1,3-glucanase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SKI6 |
YGR195W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU23 |
YDL098C |
Component of the U4/U6.U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU66 |
YOR308C |
Component of the U4/U6.U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Two-hybrid |
| SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEM13 |
YDR044W |
Coproporphyrinogen III oxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSK1 |
YAL017W |
PAS domain-containing serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCJ1 |
YMR214W |
One of several homologs of bacterial chaperone DnaJ |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MCM2 |
YBL023C |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC3 |
YER008C |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LPL1 |
YOR059C |
Phospholipase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EDC3 |
YEL015W |
Non-essential conserved protein with a role in mRNA decapping |
physical |
1 |
1 |
1 |
Co-localization |
| DNM1 |
YLL001W |
Dynamin-related GTPase involved in mitochondrial organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| LSP1 |
YPL004C |
Eisosome core component |
physical |
1 |
1 |
1 |
PCA |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| APP1 |
YNL094W |
Phosphatidate phosphatase, converts phosphatidate to diacylglycerol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PLN1 |
YKR046C |
Perilipin, involved in formation and stability of lipid droplets |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GLC8 |
YMR311C |
Regulatory subunit of protein phosphatase 1 (Glc7p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAF120 |
YNL278W |
Part of the CCR4-NOT transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PCL7 |
YIL050W |
Pho85p cyclin of the Pho80p subfamily |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PGM2 |
YMR105C |
Phosphoglucomutase |
physical |
1 |
1 |
1 |
PCA |
| COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DBF20 |
YPR111W |
Ser/Thr kinase involved in late nuclear division |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRS6 |
YOR370C |
Rab escort protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP122 |
YGL016W |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPP2 |
YER062C |
DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSK2 |
YOL045W |
PAS-domain containing serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GRS1 |
YBR121C |
Cytoplasmic and mitochondrial glycyl-tRNA synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIN8 |
YEL061C |
Bipolar kinesin motor protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PTC7 |
YHR076W |
Type 2C serine/threonine protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HYM1 |
YKL189W |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| PPE1 |
YHR075C |
Protein with carboxyl methyl esterase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS1 |
YKR063C |
Endonuclease involved in pre-rRNA processing at both ends of ITS2 |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| KEL2 |
YGR238C |
Protein that negatively regulates mitotic exit |
physical |
1 |
1 |
1 |
Two-hybrid |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIP5 |
YFR016C |
Protein that positively regulates actin assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERR3 |
YMR323W |
Enolase, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
1 |
1 |
1 |
PCA |
| SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KIC1 |
YHR102W |
Protein kinase of the PAK/Ste20 family, required for cell integrity |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FPK1 |
YNR047W |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD9 |
YGR041W |
Protein involved in bud-site selection |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GAL3 |
YDR009W |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDH2 |
YOL126C |
Cytoplasmic malate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MDH2 |
YOL126C |
Cytoplasmic malate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD53 |
YPL153C |
DNA damage response kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MCM4 |
YPR019W |
Essential helicase component of heterohexameric MCM2-7 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MMS4 |
YBR098W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMD1 |
YER132C |
Protein with an N-terminal kelch-like domain |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CYS3 |
YAL012W |
Cystathionine gamma-lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG5 |
YPL149W |
Conserved protein involved in autophagy and the Cvt pathway |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ATG5 |
YPL149W |
Conserved protein involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAL2 |
YLR081W |
Galactose permease |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| JJJ1 |
YNL227C |
Co-chaperone that stimulates the ATPase activity of Ssa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTQ2 |
YDR140W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC43 |
YGL155W |
Beta subunit of geranylgeranyltransferase type I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCM10 |
YIL150C |
Essential chromatin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCI1 |
YOR180C |
Peroxisomal protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| FAR3 |
YMR052W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| FIG1 |
YBR040W |
Integral membrane protein required for efficient mating |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
physical |
1 |
1 |
1 |
Biochemical Activity |
| IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MSB2 |
YGR014W |
Mucin family member involved in various signaling pathways |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HUA2 |
YOR284W |
Cytoplasmic protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDL1 |
YLR254C |
Homolog of nuclear distribution factor NudE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IME1 |
YJR094C |
Master regulator of meiosis that is active only during meiotic events |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRM3 |
YPL192C |
Protein required for nuclear envelope fusion during karyogamy |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RBD2 |
YPL246C |
Possible rhomboid protease |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPN2 |
YOR262W |
Putative GTPase with a specific role in RNA pol II and polIII biogenes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRR1 |
YKL116C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP40 |
YPL222W |
Mitochondrial AMPylator in the pseudokinase selenoprotein-O family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RNA15 |
YGL044C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC21 |
YOR074C |
Thymidylate synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMC2 |
YFR031C |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES4 |
YOR189W |
Component of the INO80 chromatiin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IES6 |
YEL044W |
Component of the INO80 chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HPC2 |
YBR215W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCD10 |
YNL062C |
Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP150 |
YJL159W |
O-mannosylated heat shock protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| KAR9 |
YPL269W |
Spindle positioning factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MDM12 |
YOL009C |
Mitochondrial outer membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD17 |
YOR368W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN3 |
YKL125W |
Protein required for transcription of rDNA by RNA polymerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC6 |
YIL068C |
Essential 88kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAM18 |
YLR008C |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIN1 |
YOR349W |
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC5 |
YDR166C |
Essential 107kDa subunit of the exocyst complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HAP4 |
YKL109W |
Transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MOB1 |
YIL106W |
Component of the mitotic exit network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCL1 |
YNL289W |
Cyclin, interacts with cyclin-dependent kinase Pho85p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUD2 |
YKL092C |
GTPase activating factor for Rsr1p/Bud1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIC1 |
YHR061C |
Rho-family GTPase interacting protein and Cdc42p effector |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| PCL5 |
YHR071W |
Cyclin |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RBL2 |
YOR265W |
Protein involved in microtubule morphogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SFT1 |
YKL006C-A |
Intra-Golgi v-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GAL1 |
YBR020W |
Galactokinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DBP1 |
YPL119C |
ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
1 |
1 |
1 |
PCA |
| DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIC2 |
YDR309C |
Rho-family GTPase interacting protein and Cdc42p effector |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REC114 |
YMR133W |
Protein involved in early stages of meiotic recombination |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| FIR1 |
YER032W |
Protein involved in 3' mRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC25 |
YER018C |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| PEX27 |
YOR193W |
Peripheral peroxisomal membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCW4 |
YGR279C |
Cell wall protein with similarity to glucanases |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RSR1 |
YGR152C |
Ras-type GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCH1 |
YGR217W |
Voltage-gated high-affinity calcium channel |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KAR1 |
YNL188W |
Protein involved in karyogamy and spindle pole body duplication |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ASH1 |
YKL185W |
Component of the Rpd3L histone deacetylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ERV29 |
YGR284C |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CYB2 |
YML054C |
Cytochrome b2 (L-lactate cytochrome-c oxidoreductase) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OXA1 |
YER154W |
Mitochondrial inner membrane insertase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIN2 |
YPL241C |
GTPase-activating protein (GAP) for Cin4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| MCR1 |
YKL150W |
Mitochondrial NADH-cytochrome b5 reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRS1 |
YOR294W |
Essential protein that binds ribosomal protein L11 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SED1 |
YDR077W |
Major stress-induced structural GPI-cell wall glycoprotein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CRG1 |
YHR209W |
S-AdoMet-dependent methyltransferase involved in lipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ECM21 |
YBL101C |
Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MDM1 |
YML104C |
PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs |
physical |
1 |
1 |
1 |
Two-hybrid |
| HBS1 |
YKR084C |
GTPase with similarity to translation release factors |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EPO1 |
YMR124W |
Protein involved in septin-ER tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
physical |
1 |
1 |
1 |
Two-hybrid |
| PTR3 |
YFR029W |
Component of the SPS plasma membrane amino acid sensor system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP17 |
YDR377W |
Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SDH1 |
YKL148C |
Flavoprotein subunit of succinate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPB1 |
YOR371C |
Multistep regulator of cAMP-PKA signaling |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HSP26 |
YBR072W |
Small heat shock protein (sHSP) with chaperone activity |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| FMO1 |
YHR176W |
Flavin-containing monooxygenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HLR1 |
YDR528W |
Protein involved in regulation of cell wall composition and integrity |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PDP3 |
YLR455W |
Component of the NuA3b histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIA1 |
YOR137C |
Protein of unassigned function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDJ2 |
YNL328C |
Constituent of the mitochondrial import motor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HSK3 |
YKL138C-A |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
| DAD3 |
YBR233W-A |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DAD4 |
YDR320C-A |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PLM2 |
YDR501W |
Putative transcription factor, contains Forkhead Associated domain |
physical |
1 |
1 |
1 |
PCA |
| EDC2 |
YER035W |
RNA-binding protein that directly activates mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NKP2 |
YLR315W |
Central kinetochore protein and subunit of the Ctf19 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTP1 |
YBR291C |
Mitochondrial inner membrane citrate transporter |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CWP2 |
YKL096W-A |
Covalently linked cell wall mannoprotein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSA2 |
YKR077W |
Putative transcriptional activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NQM1 |
YGR043C |
Transaldolase of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| AIM26 |
YKL037W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LAG2 |
YOL025W |
Protein that negatively regulates the SCF E3-ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GLN4 |
YOR168W |
Glutamine tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAS5 |
YOR213C |
Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRG7 |
YOR305W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RMA1 |
YKL132C |
Putative dihydrofolate synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAP3 |
YNL239W |
Cysteine aminopeptidase with homocysteine-thiolactonase activity |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEA4 |
YBL104C |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARO3 |
YDR035W |
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GAA1 |
YLR088W |
Subunit of the GPI:protein transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SND1 |
YDR186C |
Protein involved in SRP-independent targeting of substrates to the ER |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MPA43 |
YNL249C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IGD1 |
YFR017C |
Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SLD5 |
YDR489W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDA1 |
YLR307W |
Chitin deacetylase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP54 |
YOL065C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NMT1 |
YLR195C |
N-myristoyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISF1 |
YMR081C |
Serine-rich, hydrophilic protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT106 |
YNL206C |
Histone chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNY1 |
YPL123C |
Vacuolar RNase of the T(2) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIA1 |
YMR316W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PKP2 |
YGL059W |
Mitochondrial protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| COX10 |
YPL172C |
Heme A:farnesyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CYT1 |
YOR065W |
Cytochrome c1 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG13 |
YGL047W |
Catalytic component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EST2 |
YLR318W |
Reverse transcriptase subunit of the telomerase holoenzyme |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SMA1 |
YPL027W |
Protein of unknown function involved in prospore membrane assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP45 |
YDL222C |
Integral membrane protein localized to mitochondria |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HEM2 |
YGL040C |
Aminolevulinate dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECL1 |
YGR146C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSR2 |
YLR019W |
Putative plasma membrane phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RBA50 |
YDR527W |
Protein involved in transcription |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SPO11 |
YHL022C |
Meiosis-specific protein required for meiotic recombination |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RCR1 |
YBR005W |
Plasma membrane (PM) ubiquitin ligase-substrate adaptor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ECM13 |
YBL043W |
Non-essential protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRY2 |
YKR013W |
Sterol binding protein involved in the export of acetylated sterols |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| AIM34 |
YMR003W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIS3 |
YJL158C |
Mannose-containing glycoprotein constituent of the cell wall |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PRY1 |
YJL079C |
Lipid binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEY1 |
YOR165W |
Dynamin-like GTPase that mediates homotypic ER fusion |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MIM1 |
YOL026C |
Mitochondrial protein required for outer membrane protein import |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MEP1 |
YGR121C |
Ammonium permease |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| INO1 |
YJL153C |
Inositol-3-phosphate synthase |
physical |
1 |
1 |
1 |
PCA |
| CGR1 |
YGL029W |
Protein involved in nucleolar integrity and processing of pre-rRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ALG12 |
YNR030W |
Alpha-1,6-mannosyltransferase localized to the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SHR5 |
YOL110W |
Palmitoyltransferase subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCW12 |
YLR110C |
Cell wall mannoprotein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MEP2 |
YNL142W |
Ammonium permease involved in regulation of pseudohyphal growth |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PEX22 |
YAL055W |
Putative peroxisomal membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIB7 |
YBR153W |
Diaminohydroxyphoshoribosylaminopyrimidine deaminase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRN1 |
YPL184C |
RNA-binding protein that may be involved in translational regulation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MRN1 |
YPL184C |
RNA-binding protein that may be involved in translational regulation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FRT1 |
YOR324C |
Tail-anchored ER membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR6 |
YGL247W |
Essential nuclear envelope integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAM2 |
YKL019W |
Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DSE2 |
YHR143W |
Daughter cell-specific secreted protein with similarity to glucanases |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CCW14 |
YLR390W-A |
Covalently linked cell wall glycoprotein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| AFB1 |
YLR040C |
MATalpha-specific a-factor blocker |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| FLO1 |
YAR050W |
Lectin-like protein involved in flocculation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FIT3 |
YOR383C |
Mannoprotein that is incorporated into the cell wall |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ATG41 |
YPL250C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| FEX2 |
YPL279C |
Protein involved in fluoride export |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DIE2 |
YGR227W |
Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BOR1 |
YNL275W |
Boron efflux transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATO2 |
YNR002C |
Putative transmembrane protein involved in export of ammonia |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PAI3 |
YMR174C |
Cytoplasmic proteinase A (Pep4p) inhibitor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| FSF1 |
YOR271C |
Putative protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMF3 |
YLR034C |
Putative divalent metal ion transporter involved in iron homeostasis |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GIS3 |
YLR094C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX8 |
YGR077C |
Intraperoxisomal organizer of the peroxisomal import machinery |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PEX8 |
YGR077C |
Intraperoxisomal organizer of the peroxisomal import machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APT2 |
YDR441C |
Potential adenine phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PUN1 |
YLR414C |
Plasma membrane protein with a role in cell wall integrity |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MUP3 |
YHL036W |
Low affinity methionine permease |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCW10 |
YMR305C |
Cell wall protein with similarity to glucanases |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET5 |
YJR137C |
Sulfite reductase beta subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIC60 |
YKR016W |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRL1 |
YOR247W |
Mannoprotein that exhibits a tight association with the cell wall |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SRL1 |
YOR247W |
Mannoprotein that exhibits a tight association with the cell wall |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| NAT4 |
YMR069W |
N alpha-acetyl-transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIC12 |
YBR262C |
Component of the MICOS complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CMC1 |
YKL137W |
Copper-binding protein of the mitochondrial intermembrane space |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSC1 |
YML128C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMC4 |
YMR194C-B |
Protein that localizes to the mitochondrial intermembrane space |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| IRC20 |
YLR247C |
E3 ubiquitin ligase and putative helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICY1 |
YMR195W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DLT1 |
YMR126C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CHM7 |
YJL049W |
Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum |
physical |
1 |
1 |
1 |
Two-hybrid |
| GMC2 |
YLR445W |
Protein involved in meiotic crossing over |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAT3 |
YLR013W |
Protein containing GATA family zinc finger motifs |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| FLX1 |
YIL134W |
Mitochondrial flavin adenine dinucleotide transporter |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GPI1 |
YGR216C |
Membrane protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HXT17 |
YNR072W |
Putative transmembrane polyol transporter |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PKP1 |
YIL042C |
Mitochondrial protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PET54 |
YGR222W |
Mitochondrial inner membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NPC2 |
YDL046W |
Sterol transport protein and functional homolog of human NPC2/He1 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SNA2 |
YDR525W-A |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MNT3 |
YIL014W |
Alpha-1,3-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPR3 |
YGR059W |
Sporulation-specific homolog of the CDC3/10/11/12 family of genes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HMS2 |
YJR147W |
Protein with similarity to heat shock transcription factors |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SIM1 |
YIL123W |
Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| QRI7 |
YDL104C |
Protein involved in threonylcarbamoyl adenosine biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DBR1 |
YKL149C |
RNA lariat debranching enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MRX11 |
YPL041C |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTC6 |
YPL183W-A |
Protein involved in translation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRY3 |
YJL078C |
GPI-anchored cell wall protein involved in export of sterols |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MTC4 |
YBR255W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRM5 |
YIL117C |
Pheromone-regulated protein, predicted to have 1 transmembrane segment |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPP1 |
YCR026C |
Nucleotide pyrophosphatase/phosphodiesterase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PHM7 |
YOL084W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NCA3 |
YJL116C |
Protein involved in mitochondrion organization |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SRL3 |
YKR091W |
Repressor of transcription at Start |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SPO73 |
YER046W |
Meiosis-specific protein required for prospore membrane morphogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDA2 |
YLR308W |
Chitin deacetylase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RTS2 |
YOR077W |
Basic zinc-finger protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAE3 |
YHR079C-A |
Meiosis-specific protein involved in meiotic recombination |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GAT4 |
YIR013C |
Protein containing GATA family zinc finger motifs |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PAU13 |
YHL046C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SPO24 |
YPR036W-A |
Small (67 amino acids) protein involved in sporulation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SEC59 |
YMR013C |
Dolichol kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RTC5 |
YOR118W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |