SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
23 |
5 |
18 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Reconstituted Complex |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
physical |
15 |
2 |
11 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
15 |
5 |
10 |
Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Enhancement, Dosage Lethality, Dosage Lethality, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
physical |
14 |
3 |
13 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-localization, Affinity Capture-MS |
UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
14 |
2 |
12 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
physical |
13 |
3 |
9 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
physical |
11 |
2 |
11 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
physical |
11 |
2 |
10 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
physical |
11 |
2 |
10 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-localization, Affinity Capture-MS |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
11 |
3 |
6 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect |
EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
physical |
10 |
2 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
physical |
9 |
2 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
9 |
4 |
5 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Rescue, Negative Genetic |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
8 |
4 |
7 |
Phenotypic Enhancement, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Enhancement, Negative Genetic |
RXT3 |
YDL076C |
Component of the Rpd3L histone deacetylase complex |
physical |
7 |
1 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
physical |
7 |
4 |
6 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Co-localization |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
7 |
2 |
4 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
6 |
2 |
6 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
6 |
3 |
5 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
6 |
3 |
5 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
6 |
3 |
5 |
Negative Genetic, Synthetic Lethality, Negative Genetic, Dosage Lethality, Dosage Lethality, Negative Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
6 |
3 |
5 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
6 |
3 |
5 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
HHT1 |
YBR010W |
Histone H3 |
genetic |
6 |
3 |
5 |
Synthetic Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Suppression |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
6 |
3 |
5 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
6 |
3 |
5 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
6 |
3 |
5 |
Phenotypic Suppression, Positive Genetic, Phenotypic Suppression, Phenotypic Enhancement, Positive Genetic, Positive Genetic |
LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
6 |
2 |
5 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
ASH1 |
YKL185W |
Component of the Rpd3L histone deacetylase complex |
physical |
6 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
6 |
3 |
4 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Dosage Lethality, Dosage Lethality, Negative Genetic |
HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
6 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
6 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
SAS2 |
YMR127C |
Histone acetyltransferase (HAT) catalytic subunit of the SAS complex |
genetic |
5 |
2 |
5 |
Negative Genetic, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
5 |
3 |
4 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Rescue, Positive Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
5 |
3 |
4 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Dosage Lethality, Dosage Lethality, Negative Genetic |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
5 |
4 |
3 |
Synthetic Rescue, Dosage Rescue, Dosage Lethality, Dosage Lethality, Negative Genetic |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
5 |
3 |
3 |
Synthetic Rescue, Synthetic Rescue, Dosage Lethality, Dosage Lethality, Phenotypic Suppression |
CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
5 |
3 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Dosage Lethality, Dosage Lethality |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
5 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
5 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
4 |
3 |
4 |
Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
HHT1 |
YBR010W |
Histone H3 |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
4 |
2 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Phenotypic Suppression |
SAS5 |
YOR213C |
Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) |
genetic |
4 |
2 |
4 |
Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
SAS4 |
YDR181C |
Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) |
genetic |
4 |
2 |
4 |
Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
4 |
3 |
3 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic, Phenotypic Suppression |
AKL1 |
YBR059C |
Ser/Thr protein kinase |
genetic |
4 |
3 |
3 |
Negative Genetic, Dosage Lethality, Dosage Lethality, Positive Genetic |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
YAP1801 |
YHR161C |
Protein of the AP180 family, involved in clathrin cage assembly |
genetic |
4 |
2 |
3 |
Negative Genetic, Dosage Lethality, Dosage Lethality, Negative Genetic |
MIP6 |
YHR015W |
Putative RNA-binding protein |
genetic |
4 |
2 |
3 |
Negative Genetic, Dosage Lethality, Dosage Lethality, Negative Genetic |
RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
4 |
2 |
3 |
Synthetic Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
4 |
2 |
3 |
Negative Genetic, Dosage Lethality, Dosage Lethality, Negative Genetic |
CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
4 |
2 |
3 |
Positive Genetic, Dosage Lethality, Dosage Lethality, Positive Genetic |
RCF2 |
YNR018W |
Cytochrome c oxidase subunit |
genetic |
4 |
2 |
3 |
Negative Genetic, Dosage Lethality, Dosage Lethality, Negative Genetic |
PRM6 |
YML047C |
Potassium transporter that mediates K+ influx |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
4 |
4 |
2 |
Phenotypic Enhancement, Dosage Growth Defect, Phenotypic Suppression, Positive Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
4 |
4 |
2 |
Phenotypic Enhancement, Dosage Growth Defect, Phenotypic Suppression, Positive Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
4 |
3 |
2 |
Dosage Lethality, Dosage Lethality, Positive Genetic, Negative Genetic |
RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
4 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Dosage Lethality, Dosage Lethality |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
4 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Dosage Lethality, Dosage Lethality |
RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
4 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Dosage Lethality, Dosage Lethality |
PET130 |
YJL023C |
Protein of unknown function |
genetic |
4 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Dosage Lethality, Dosage Lethality |
ECM5 |
YMR176W |
Subunit of the Snt2C complex |
physical |
4 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
SNT2 |
YGL131C |
Subunit of Snt2C complex, RING finger ubiquitin ligase (E3) |
physical |
4 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
4 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
ADA2 |
YDR448W |
Transcription coactivator |
genetic |
4 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
genetic |
4 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
4 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
3 |
3 |
3 |
Phenotypic Enhancement, Synthetic Rescue, Negative Genetic |
HHT2 |
YNL031C |
Histone H3 |
physical |
3 |
3 |
3 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS |
HHT2 |
YNL031C |
Histone H3 |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
2 |
3 |
Positive Genetic, Phenotypic Suppression, Positive Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Synthetic Rescue, Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic |
ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
3 |
2 |
3 |
Phenotypic Suppression, Negative Genetic, Negative Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect |
DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Negative Genetic, Synthetic Rescue |
ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Positive Genetic, Positive Genetic |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
TIM13 |
YGR181W |
Mitochondrial intermembrane space protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
SIR3 |
YLR442C |
Silencing protein |
genetic |
3 |
1 |
3 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
INO2 |
YDR123C |
Transcription factor |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
3 |
3 |
2 |
Synthetic Growth Defect, Positive Genetic, Negative Genetic |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
3 |
3 |
2 |
Phenotypic Suppression, Synthetic Rescue, Negative Genetic |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Negative Genetic |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Negative Genetic |
IOC3 |
YFR013W |
Subunit of the Isw1a complex |
genetic |
3 |
2 |
2 |
Positive Genetic, Dosage Lethality, Dosage Lethality |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Dosage Lethality, Dosage Lethality |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Positive Genetic |
YPK1 |
YKL126W |
S/T protein kinase |
genetic |
3 |
2 |
2 |
Negative Genetic, Dosage Lethality, Dosage Lethality |
YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Positive Genetic |
TDP1 |
YBR223C |
Tyrosyl-DNA phosphodiesterase I |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Synthetic Lethality |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Negative Genetic |
YPT1 |
YFL038C |
Rab family GTPase |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Negative Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Negative Genetic |
GAL83 |
YER027C |
One of three alternate beta-subunits of the Snf1 kinase complex |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Negative Genetic |
BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
ADR1 |
YDR216W |
Carbon source-responsive zinc-finger transcription factor |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Dosage Lethality, Dosage Lethality |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
GAL80 |
YML051W |
Transcriptional regulator involved in the repression of GAL genes |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Negative Genetic |
POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
3 |
2 |
2 |
Negative Genetic, Dosage Lethality, Dosage Lethality |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Positive Genetic |
GEM1 |
YAL048C |
Outer mitochondrial membrane GTPase, subunit of the ERMES complex |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Positive Genetic |
PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
genetic |
3 |
2 |
2 |
Positive Genetic, Dosage Lethality, Dosage Lethality |
GPI18 |
YBR004C |
Functional ortholog of human PIG-V |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
CBP4 |
YGR174C |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
genetic |
3 |
2 |
2 |
Positive Genetic, Dosage Lethality, Dosage Lethality |
AIM19 |
YIL087C |
Protein of unknown function |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Negative Genetic |
AMN1 |
YBR158W |
Modulator of cell separation and mitotic exit |
genetic |
3 |
1 |
2 |
Dosage Lethality, Dosage Lethality, Dosage Lethality |
ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
3 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
3 |
1 |
2 |
Dosage Lethality, Dosage Lethality, Dosage Lethality |
SLD3 |
YGL113W |
Protein involved in the initiation of DNA replication |
genetic |
3 |
3 |
1 |
Phenotypic Enhancement, Dosage Growth Defect, Phenotypic Suppression |
SLD2 |
YKL108W |
Single-stranded DNA origin-binding and annealing protein |
genetic |
3 |
3 |
1 |
Phenotypic Enhancement, Dosage Growth Defect, Phenotypic Suppression |
SVS1 |
YPL163C |
Cell wall and vacuolar protein |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, quantitative reverse transcription polymerase chain reaction evidence |
TSL1 |
YML100W |
Large subunit of trehalose 6-phosphate synthase/phosphatase complex |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Suppression |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
HHF1 |
YBR009C |
Histone H4 |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
genetic |
2 |
2 |
2 |
Dosage Lethality, Positive Genetic |
STB5 |
YHR178W |
Transcription factor |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
PET9 |
YBL030C |
Major ADP/ATP carrier of the mitochondrial inner membrane |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Dosage Rescue |
RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Synthetic Rescue |
ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Suppression |
DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Suppression |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FRT2 |
YAL028W |
Tail-anchored ER membrane protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ENO1 |
YGR254W |
Enolase I, a phosphopyruvate hydratase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TOP1 |
YOL006C |
Topoisomerase I |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TRK1 |
YJL129C |
Component of the Trk1p-Trk2p potassium transport system |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
YAL065C |
YAL065C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YBL055C |
YBL055C |
3'-->5' exonuclease and endonuclease with a possible role in apoptosis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TEC1 |
YBR083W |
Transcription factor targeting filamentation genes and Ty1 expression |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YBR238C |
YBR238C |
Mitochondrial membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YBR242W |
YBR242W |
5'-deoxynucleotidase involved in deoxyribonucleoside monophosphate deg |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SAP1 |
YER047C |
Putative ATPase of the AAA family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RTR1 |
YER139C |
Dual specificity protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS25A |
YGR027C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YHL042W |
YHL042W |
Endoplasmic reticulum protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YHL017W |
YHL017W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YHL012W |
YHL012W |
Putative UTP glucose-1-phosphate uridylyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SFH5 |
YJL145W |
Unusual phosphatidylinositol transfer protein (PITP) that binds heme |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YUR1 |
YJL139C |
Mannosyltransferase involved in protein N-glycosylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YJL070C |
YJL070C |
Putative metallo-dependent hydrolase superfamily protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YET1 |
YKL065C |
Endoplasmic reticulum transmembrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SAP190 |
YKR028W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YML119W |
YML119W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YMR155W |
YMR155W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YNR021W |
YNR021W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TOM6 |
YOR045W |
Component of the TOM (translocase of outer membrane) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VHS3 |
YOR054C |
Negative regulatory subunit of protein phosphatase 1 Ppz1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RTC6 |
YPL183W-A |
Protein involved in translation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPR114W |
YPR114W |
Protein distantly similar to ceramide synthases, Lag1p and Lac1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CMP2 |
YML057W |
Calcineurin A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FYV10 |
YIL097W |
Subunit of GID complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAD55 |
YDR076W |
Protein that stimulates strand exchange |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
PSR1 |
YLL010C |
Plasma membrane-associated protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OMS1 |
YDR316W |
Protein integral to the mitochondrial membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EPT1 |
YHR123W |
sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CSM2 |
YIL132C |
Subunit of the Shu complex (aka PCSS complex) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PEX29 |
YDR479C |
ER-resident protein involved in peroxisomal biogenesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MAD3 |
YJL013C |
Subunit of spindle-assembly checkpoint complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KTI12 |
YKL110C |
Protein that plays a role in modification of tRNA wobble nucleosides |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CTK2 |
YJL006C |
Beta subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OST6 |
YML019W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
PEX30 |
YLR324W |
ER-resident protein involved in peroxisomal biogenesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OAF1 |
YAL051W |
Oleate-activated transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
REC8 |
YPR007C |
Meiosis-specific component of the sister chromatid cohesion complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HXK1 |
YFR053C |
Hexokinase isoenzyme 1 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PPT1 |
YGR123C |
Protein serine/threonine phosphatase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NSG1 |
YHR133C |
Protein involved in regulation of sterol biosynthesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MLO127 |
YJR039W |
Mitochondrial protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GMC1 |
YDR506C |
Protein involved in meiotic progression |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MME1 |
YMR166C |
Transporter of the mitochondrial inner membrane that exports magnesium |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MTC6 |
YHR151C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
regulation |
2 |
2 |
1 |
chromatin immunoprecipitation-qPCR evidence, quantitative reverse transcription polymerase chain reaction evidence |
CDC45 |
YLR103C |
DNA replication initiation factor |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Phenotypic Suppression |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
XBP1 |
YIL101C |
Transcriptional repressor |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Co-localization |
SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Synthetic Rescue |
SLD7 |
YOR060C |
Protein with a role in chromosomal DNA replication |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Phenotypic Suppression |
CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
2 |
2 |
1 |
Two-hybrid, Reconstituted Complex |
RAD53 |
YPL153C |
DNA damage response kinase |
physical |
2 |
2 |
1 |
Biochemical Activity, Affinity Capture-Western |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Enhancement |
CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
2 |
2 |
1 |
Two-hybrid, Reconstituted Complex |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
PRP45 |
YAL032C |
Protein required for pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
FTH1 |
YBR207W |
Putative high affinity iron transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
IMG1 |
YCR046C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
BUD3 |
YCL014W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
LCD1 |
YDR499W |
Essential protein required for the DNA integrity checkpoint pathways |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PAP1 |
YKR002W |
Poly(A) polymerase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
NRP1 |
YDL167C |
Putative RNA binding protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
NAB6 |
YML117W |
Putative RNA-binding protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RAM1 |
YDL090C |
Beta subunit of the CAAX farnesyltransferase (FTase) |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RRN11 |
YML043C |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RSC2 |
YLR357W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SLM5 |
YCR024C |
Mitochondrial asparaginyl-tRNA synthetase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
TSR2 |
YLR435W |
Protein with a potential role in pre-rRNA processing |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
VPS20 |
YMR077C |
Myristoylated subunit of the ESCRT-III complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
VPS25 |
YJR102C |
Component of the ESCRT-II complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SUR7 |
YML052W |
Plasma membrane protein, component of eisosomes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
STE4 |
YOR212W |
G protein beta subunit |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SCD5 |
YOR329C |
Protein required for normal actin organization and endocytosis |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SWP82 |
YFL049W |
Member of the SWI/SNF chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
TOS8 |
YGL096W |
Homeodomain-containing protein and putative transcription factor |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
STP2 |
YHR006W |
Transcription factor |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
WTM2 |
YOR229W |
Transcriptional modulator |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RSC3 |
YDR303C |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RSC30 |
YHR056C |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SNQ2 |
YDR011W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
TPO2 |
YGR138C |
Polyamine transporter of the major facilitator superfamily |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
UGA4 |
YDL210W |
GABA (gamma-aminobutyrate) permease |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
TAT2 |
YOL020W |
High affinity tryptophan and tyrosine permease |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SMY2 |
YBR172C |
GYF domain protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SDS22 |
YKL193C |
Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SRO77 |
YBL106C |
Protein with roles in exocytosis and cation homeostasis |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
VPS70 |
YJR126C |
Protein of unknown function involved in vacuolar protein sorting |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
TVP38 |
YKR088C |
Integral membrane protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
VTC3 |
YPL019C |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SSO1 |
YPL232W |
Plasma membrane t-SNARE |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SEC15 |
YGL233W |
Essential 113 kDa subunit of the exocyst complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
TPC1 |
YGR096W |
Mitochondrial membrane transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
YPC1 |
YBR183W |
Alkaline ceramidase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RSF1 |
YMR030W |
Protein required for respiratory growth |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
TPS3 |
YMR261C |
Regulatory subunit of trehalose-6-phosphate synthase/phosphatase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
YME2 |
YMR302C |
Integral inner mitochondrial membrane protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
TOM7 |
YNL070W |
Component of the TOM (translocase of outer membrane) complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
TPN1 |
YGL186C |
Plasma membrane pyridoxine (vitamin B6) transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
TIM17 |
YJL143W |
Essential component of the TIM23 complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SAM50 |
YNL026W |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
TOM5 |
YPR133W-A |
Component of the TOM (translocase of outer membrane) complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
UBX3 |
YDL091C |
Clathrin-coated vesicle component, regulator of endocytosis |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
UBX5 |
YDR330W |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SPS22 |
YCL048W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SSF2 |
YDR312W |
Protein required for ribosomal large subunit maturation |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RPL24B |
YGR148C |
Ribosomal 60S subunit protein L24B |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RPL37A |
YLR185W |
Ribosomal 60S subunit protein L37A |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
TRM10 |
YOL093W |
tRNA methyltransferase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RPS26A |
YGL189C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RPP1 |
YHR062C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SLM2 |
YNL047C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SAP4 |
YGL229C |
Protein required for function of the Sit4p protein phosphatase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
YRO2 |
YBR054W |
Protein with a putative role in response to acid stress |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
YSC83 |
YHR017W |
Non-essential mitochondrial protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
YJR124C |
YJR124C |
Putative protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
YKR075C |
YKR075C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
YMR295C |
YMR295C |
Protein of unknown function that associates with ribosomes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
YNL046W |
YNL046W |
Putative protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
YOR283W |
YOR283W |
Phosphatase with a broad substrate specificity |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SYH1 |
YPL105C |
Protein of unknown function that influences nuclear pore distribution |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
TDA6 |
YPR157W |
Putative protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
SPS18 |
YNL204C |
Protein of unknown function, contains a putative zinc-binding domain |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
BSP1 |
YPR171W |
Adapter that links synaptojanins to the cortical actin cytoskeleton |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
FLC2 |
YAL053W |
Putative calcium channel involved in calcium release under hypotonic |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
DIA4 |
YHR011W |
Probable mitochondrial seryl-tRNA synthetase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
NGL2 |
YMR285C |
Protein involved in 5.8S rRNA processing |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
CNA1 |
YLR433C |
Calcineurin A |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
GSP2 |
YOR185C |
GTP binding protein (mammalian Ranp homolog) |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
AMF1 |
YOR378W |
Low affinity NH4+ transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
CYC8 |
YBR112C |
General transcriptional co-repressor |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
DSS1 |
YMR287C |
3'-5' exoribonuclease |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
HRT3 |
YLR097C |
Putative SCF-ubiquitin ligase F-box protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PTC7 |
YHR076W |
Type 2C serine/threonine protein phosphatase (PP2C) |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
LUG1 |
YLR352W |
Protein of unknown function with similarity to F-box proteins |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MSS116 |
YDR194C |
Mitochondrial transcription elongation factor |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
CTR1 |
YPR124W |
High-affinity copper transporter of plasma membrane |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
BTN2 |
YGR142W |
v-SNARE binding protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RAD26 |
YJR035W |
Protein involved in transcription-coupled nucleotide excision repair |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RED1 |
YLR263W |
Protein component of the synaptonemal complex axial elements |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
AFG3 |
YER017C |
Mitochondrial inner membrane m-AAA protease component |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
ALR1 |
YOL130W |
Plasma membrane Mg(2+) transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PPG1 |
YNR032W |
Serine protein phosphatase involved in formation of FAR complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MTF1 |
YMR228W |
Mitochondrial RNA polymerase specificity factor |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
MRX16 |
YDR132C |
Protein that associates with the large mitoribosomal subunit |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RBD2 |
YPL246C |
Possible rhomboid protease |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
ITT1 |
YML068W |
Protein that modulates the efficiency of translation termination |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MDR1 |
YGR100W |
Cytoplasmic GTPase-activating protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PEX13 |
YLR191W |
Peroxisomal importomer complex component |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PEX2 |
YJL210W |
RING-finger peroxin and E3 ubiquitin ligase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
CDC31 |
YOR257W |
Calcium-binding component of the spindle pole body (SPB) half-bridge |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
NOT5 |
YPR072W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
BDP1 |
YNL039W |
Essential subunit of RNA polymerase III transcription factor (TFIIIB) |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MPS2 |
YGL075C |
Essential membrane protein localized at nuclear envelope and SPBs |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
CNM67 |
YNL225C |
Component of the spindle pole body outer plaque |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
NAM9 |
YNL137C |
Mitochondrial ribosomal component of the small subunit |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
BUD8 |
YLR353W |
Protein involved in bud-site selection |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PPR1 |
YLR014C |
Zinc finger transcription factor |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
GIC1 |
YHR061C |
Rho-family GTPase interacting protein and Cdc42p effector |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
BPT1 |
YLL015W |
ABC type transmembrane transporter of MRP/CFTR family |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PEX25 |
YPL112C |
Peripheral peroxisomal membrane peroxin |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MGA1 |
YGR249W |
Protein similar to heat shock transcription factor |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MSB4 |
YOL112W |
GTPase-activating protein of the Ras superfamily |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ENT2 |
YLR206W |
Epsin-like protein required for endocytosis and actin patch assembly |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MATALPHA2 |
YCR039C |
Homeobox-domain protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
OSW7 |
YFR039C |
Protein involved in outer spore wall assembly |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
CCC1 |
YLR220W |
Vacuolar Fe2+/Mn2+ transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MET4 |
YNL103W |
Leucine-zipper transcriptional activator |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
HNM1 |
YGL077C |
Plasma membrane transporter for choline, ethanolamine, and carnitine |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
GEF1 |
YJR040W |
Voltage-gated chloride channel |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
HEM14 |
YER014W |
Protoporphyrinogen oxidase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
DAL5 |
YJR152W |
Allantoate permease |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
FUN26 |
YAL022C |
High affinity, broad selectivity, nucleoside/nucleobase transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MIG3 |
YER028C |
Transcriptional regulator |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
HRD3 |
YLR207W |
ER membrane protein that plays a central role in ERAD |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
OCH1 |
YGL038C |
Mannosyltransferase of the cis-Golgi apparatus |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
IFA38 |
YBR159W |
Microsomal beta-keto-reductase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PHR1 |
YOR386W |
DNA photolyase involved in photoreactivation |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
FMP23 |
YBR047W |
Putative protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
FCY21 |
YER060W |
Putative purine-cytosine permease |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
IAI11 |
YBL059W |
Putative mitochondrial protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MSC7 |
YHR039C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
FUN14 |
YAL008W |
Integral mitochondrial outer membrane (MOM) protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
IRC8 |
YJL051W |
Bud tip localized protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
BYE1 |
YKL005C |
Negative regulator of transcription elongation |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MEF1 |
YLR069C |
Mitochondrial elongation factor involved in translational elongation |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
NAM2 |
YLR382C |
Mitochondrial leucyl-tRNA synthetase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
PAD1 |
YDR538W |
Phenylacrylic acid decarboxylase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
FOL1 |
YNL256W |
Multifunctional enzyme of the folic acid biosynthesis pathway |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
MRPS12 |
YNR036C |
Mitochondrial protein |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
ISM1 |
YPL040C |
Mitochondrial isoleucyl-tRNA synthetase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RIM4 |
YHL024W |
Putative RNA-binding protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
AVT3 |
YKL146W |
Vacuolar transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
HXT10 |
YFL011W |
Hexose transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
FRE8 |
YLR047C |
Protein with sequence similarity to iron/copper reductases |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RGM1 |
YMR182C |
Putative zinc finger DNA binding transcription factor |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MSK1 |
YNL073W |
Mitochondrial lysine-tRNA synthetase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
GSC2 |
YGR032W |
Catalytic subunit of 1,3-beta-glucan synthase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ALO1 |
YML086C |
D-Arabinono-1,4-lactone oxidase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RIF2 |
YLR453C |
Protein that binds to the Rap1p C-terminus |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
HXT1 |
YHR094C |
Low-affinity glucose transporter of the major facilitator superfamily |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PTR2 |
YKR093W |
Integral membrane peptide transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ENA2 |
YDR039C |
P-type ATPase sodium pump |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ENA5 |
YDR038C |
Protein with similarity to P-type ATPase sodium pumps |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
PMC1 |
YGL006W |
Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ITR1 |
YDR497C |
Myo-inositol transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
DCW1 |
YKL046C |
Putative mannosidase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ATG41 |
YPL250C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
FSF1 |
YOR271C |
Putative protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PEX8 |
YGR077C |
Intraperoxisomal organizer of the peroxisomal import machinery |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
COX20 |
YDR231C |
Mitochondrial inner membrane protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ARN1 |
YHL040C |
ARN family transporter for siderophore-iron chelates |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MPC1 |
YGL080W |
Highly conserved subunit of mitochondrial pyruvate carrier (MPC) |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MIC27 |
YNL100W |
Component of the MICOS complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MPC2 |
YHR162W |
Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
GRX7 |
YBR014C |
Cis-golgi localized monothiol glutaredoxin |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ICY1 |
YMR195W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
HEM25 |
YDL119C |
Mitochondrial glycine transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PRM1 |
YNL279W |
Pheromone-regulated multispanning membrane protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
FEN2 |
YCR028C |
Plasma membrane H+-pantothenate symporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
JEN1 |
YKL217W |
Monocarboxylate/proton symporter of the plasma membrane |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
HXT17 |
YNR072W |
Putative transmembrane polyol transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
AIM10 |
YER087W |
Protein with similarity to tRNA synthetases |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
MRX19 |
YDL183C |
Protein that may form an active mitochondrial KHE system |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ERJ5 |
YFR041C |
Type I membrane protein with a J domain |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
QRI5 |
YLR204W |
Mitochondrial inner membrane protein |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
BNA4 |
YBL098W |
Kynurenine 3-monooxygenase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MSR1 |
YHR091C |
Mitochondrial arginyl-tRNA synthetase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
IRC21 |
YMR073C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
REX3 |
YLR107W |
RNA exonuclease |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RME1 |
YGR044C |
Zinc finger protein involved in control of meiosis |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
MSY1 |
YPL097W |
Mitochondrial tyrosyl-tRNA synthetase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MSW1 |
YDR268W |
Mitochondrial tryptophanyl-tRNA synthetase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
RIM2 |
YBR192W |
Mitochondrial pyrimidine nucleotide transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
PHM8 |
YER037W |
Lysophosphatidic acid (LPA) phosphatase, nucleotidase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PGK1 |
YCR012W |
3-phosphoglycerate kinase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
LAS17 |
YOR181W |
Actin assembly factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
IQG1 |
YPL242C |
Actin filament binding protein that enhances actin ring formation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
AGA2 |
YGL032C |
Adhesion subunit of a-agglutinin of a-cells |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PPM2 |
YOL141W |
AdoMet-dependent tRNA methyltransferase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SAG1 |
YJR004C |
Alpha-agglutinin of alpha-cells |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CAP1 |
YKL007W |
Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BAP3 |
YDR046C |
Amino acid permease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MEP3 |
YPR138C |
Ammonium permease of high capacity and low affinity |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CAR1 |
YPL111W |
Arginase, catabolizes arginine to ornithine and urea |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ASN1 |
YPR145W |
Asparagine synthetase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MET3 |
YJR010W |
ATP sulfurylase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CIN5 |
YOR028C |
Basic leucine zipper (bZIP) transcription factor of the yAP-1 family |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
LSC2 |
YGR244C |
Beta subunit of succinyl-CoA ligase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CHA1 |
YCL064C |
Catabolic L-serine (L-threonine) deaminase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TRM8 |
YDL201W |
Catalytic subunit of a tRNA methyltransferase complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FIG2 |
YCR089W |
Cell wall adhesin, expressed specifically during mating |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SCW4 |
YGR279C |
Cell wall protein with similarity to glucanases |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MET6 |
YER091C |
Cobalamin-independent methionine synthase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RTT102 |
YGR275W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
VPS36 |
YLR417W |
Component of the ESCRT-II complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
VPS25 |
YJR102C |
Component of the ESCRT-II complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
OYE3 |
YPL171C |
Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
OYE2 |
YHR179W |
Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YOR302W |
YOR302W |
CPA1 uORF |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PCL1 |
YNL289W |
Cyclin, interacts with cyclin-dependent kinase Pho85p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PCL2 |
YDL127W |
Cyclin, interacts with cyclin-dependent kinase Pho85p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CYS4 |
YGR155W |
Cystathionine beta-synthase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ALD3 |
YMR169C |
Cytoplasmic aldehyde dehydrogenase |
regulation |
1 |
1 |
1 |
northern blot evidence |
OCA4 |
YCR095C |
Cytoplasmic protein required for replication of Brome mosaic virus |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GIP3 |
YPL137C |
Cytoplasmic protein that regulates protein phosphatase 1 Glc7p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CTT1 |
YGR088W |
Cytosolic catalase T |
regulation |
1 |
1 |
1 |
northern blot evidence |
SHM2 |
YLR058C |
Cytosolic serine hydroxymethyltransferase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DIP5 |
YPL265W |
Dicarboxylic amino acid permease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DAK1 |
YML070W |
Dihydroxyacetone kinase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HSP104 |
YLL026W |
Disaggregase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
PIF1 |
YML061C |
DNA helicase, potent G-quadruplex DNA binder/unwinder |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
BSC3 |
YLR465C |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
PIL1 |
YGR086C |
Eisosome core component |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SAE2 |
YGL175C |
Endonuclease required for telomere elongation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YPL264C |
YPL264C |
Endoplasmic reticulum protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YPT35 |
YHR105W |
Endosomal protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SYN8 |
YAL014C |
Endosomal SNARE related to mammalian syntaxin 8 |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MPS2 |
YGL075C |
Essential membrane protein localized at nuclear envelope and SPBs |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPN3 |
YER021W |
Essential non-ATPase regulatory subunit of the 26S proteasome lid |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MAK5 |
YBR142W |
Essential nucleolar protein |
regulation |
1 |
1 |
1 |
northern blot evidence |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
regulation |
1 |
1 |
1 |
northern blot evidence |
PXR1 |
YGR280C |
Essential protein involved in rRNA and snoRNA maturation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NTR2 |
YKR022C |
Essential protein that forms a dimer with Ntr1p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DAD4 |
YDR320C-A |
Essential subunit of the Dam1 complex (aka DASH complex) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RRP4 |
YHR069C |
Exosome non-catalytic core component |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
MRK1 |
YDL079C |
Glycogen synthase kinase 3 (GSK-3) homolog |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MKC7 |
YDR144C |
GPI-anchored aspartyl protease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPI1 |
YER150W |
GPI-anchored cell wall protein involved in weak acid resistance |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HPF1 |
YOL155C |
Haze-protective mannoprotein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CTR1 |
YPR124W |
High-affinity copper transporter of plasma membrane |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FTR1 |
YER145C |
High affinity iron permease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MUP1 |
YGR055W |
High affinity methionine permease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TAT2 |
YOL020W |
High affinity tryptophan and tyrosine permease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FUI1 |
YBL042C |
High affinity uridine permease, localizes to the plasma membrane |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MPC3 |
YGR243W |
Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HTZ1 |
YOL012C |
Histone variant H2AZ |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SRC1 |
YML034W |
Inner nuclear membrane protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
EMP46 |
YLR080W |
Integral membrane component of ER-derived COPII-coated vesicles |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SKG6 |
YHR149C |
Integral membrane protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YNL194C |
YNL194C |
Integral membrane protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
KIP3 |
YGL216W |
Kinesin-related antiparallel sliding motor protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
KIP1 |
YBL063W |
Kinesin-related motor protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
KIP2 |
YPL155C |
Kinesin-related motor protein involved in mitotic spindle positioning |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SLK19 |
YOR195W |
Kinetochore-associated protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CPA2 |
YJR109C |
Large subunit of carbamoyl phosphate synthetase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HXT3 |
YDR345C |
Low affinity glucose transporter of the major facilitator superfamily |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MUP3 |
YHL036W |
Low affinity methionine permease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
LSM4 |
YER112W |
Lsm (Like Sm) protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PET9 |
YBL030C |
Major ADP/ATP carrier of the mitochondrial inner membrane |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
URA7 |
YBL039C |
Major CTP synthase isozyme (see also URA8) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RNR1 |
YER070W |
Major isoform of large subunit of ribonucleotide-diphosphate reductase |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
MET13 |
YGL125W |
Major isozyme of methylenetetrahydrofolate reductase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SED1 |
YDR077W |
Major stress-induced structural GPI-cell wall glycoprotein |
regulation |
1 |
1 |
1 |
northern blot evidence |
MAL31 |
YBR298C |
Maltose permease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
IME1 |
YJR094C |
Master regulator of meiosis that is active only during meiotic events |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
HFM1 |
YGL251C |
Meiosis specific DNA helicase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ECM11 |
YDR446W |
Meiosis-specific protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NDT80 |
YHR124W |
Meiosis-specific transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-qPCR evidence |
MPD2 |
YOL088C |
Member of the protein disulfide isomerase (PDI) family |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SDH4 |
YDR178W |
Membrane anchor subunit of succinate dehydrogenase (SDH) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SMK1 |
YPR054W |
Middle sporulation-specific mitogen-activated protein kinase (MAPK) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
AAT1 |
YKL106W |
Mitochondrial aspartate aminotransferase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CLD1 |
YGR110W |
Mitochondrial cardiolipin-specific phospholipase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NDE2 |
YDL085W |
Mitochondrial external NADH dehydrogenase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MAE1 |
YKL029C |
Mitochondrial malic enzyme |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YFH1 |
YDL120W |
Mitochondrial matrix iron chaperone |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
OM14 |
YBR230C |
Mitochondrial outer membrane receptor for cytosolic ribosomes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MRPL49 |
YJL096W |
Mitochondrial ribosomal protein of the large subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MRPS28 |
YDR337W |
Mitochondrial ribosomal protein of the small subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PET123 |
YOR158W |
Mitochondrial ribosomal protein of the small subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SHM1 |
YBR263W |
Mitochondrial serine hydroxymethyltransferase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PCP1 |
YGR101W |
Mitochondrial serine protease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
JEN1 |
YKL217W |
Monocarboxylate/proton symporter of the plasma membrane |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MER1 |
YNL210W |
mRNA-binding protein required for meiosis-specific mRNA splicing |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MTR2 |
YKL186C |
mRNA transport regulator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MSC6 |
YOR354C |
Multicopy suppressor of HER2 involved in mitochondrial translation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
QDR1 |
YIL120W |
Multidrug transporter of the major facilitator superfamily |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GPD1 |
YDL022W |
NAD-dependent glycerol-3-phosphate dehydrogenase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YKL107W |
YKL107W |
NADH-dependent aldehyde reductase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RGS2 |
YOR107W |
Negative regulator of glucose-induced cAMP signaling |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FRQ1 |
YDR373W |
N-myristoylated calcium-binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ECM8 |
YBR076W |
Non-essential protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ADE1 |
YAR015W |
N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ATC1 |
YDR184C |
Nuclear protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
INO80 |
YGL150C |
Nucleosome spacing factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RAD16 |
YBR114W |
Nucleotide excision repair (NER) protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MET17 |
YLR303W |
O-acetyl homoserine-O-acetyl serine sulfhydrylase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HSP150 |
YJL159W |
O-mannosylated heat shock protein |
regulation |
1 |
1 |
1 |
northern blot evidence |
ARH1 |
YDR376W |
Oxidoreductase of the mitochondrial inner membrane |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CAF120 |
YNL278W |
Part of the CCR4-NOT transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
STR3 |
YGL184C |
Peroxisomal cystathionine beta-lyase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PEX13 |
YLR191W |
Peroxisomal importomer complex component |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PEX28 |
YHR150W |
Peroxisomal integral membrane peroxin |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PRM7 |
YDL039C |
Pheromone-regulated protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PDR16 |
YNL231C |
Phosphatidylinositol transfer protein (PITP) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PSD2 |
YGR170W |
Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PLB3 |
YOL011W |
Phospholipase B (lysophospholipase) involved in lipid metabolism |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PLB1 |
YMR008C |
Phospholipase B (lysophospholipase) involved in lipid metabolism |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SIP18 |
YMR175W |
Phospholipid-binding hydrophilin |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SEC53 |
YFL045C |
Phosphomannomutase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ERG8 |
YMR220W |
Phosphomevalonate kinase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
VAC17 |
YCL063W |
Phosphoprotein involved in vacuole inheritance |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SNF3 |
YDL194W |
Plasma membrane low glucose sensor, regulates glucose transport |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ARR3 |
YPR201W |
Plasma membrane metalloid/H+ antiporter |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SUR7 |
YML052W |
Plasma membrane protein, component of eisosomes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SSU1 |
YPL092W |
Plasma membrane sulfite pump involved in sulfite metabolism |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
QDR2 |
YIL121W |
Plasma membrane transporter of the major facilitator superfamily |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ALR2 |
YFL050C |
Probable Mg(2+) transporter |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BLM10 |
YFL007W |
Proteasome activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GAR1 |
YHR089C |
Protein component of the H/ACA snoRNP pseudouridylase complex |
regulation |
1 |
1 |
1 |
northern blot evidence |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPS24B |
YIL069C |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPS14B |
YJL191W |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GAT4 |
YIR013C |
Protein containing GATA family zinc finger motifs |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PDI1 |
YCL043C |
Protein disulfide isomerase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NGL2 |
YMR285C |
Protein involved in 5.8S rRNA processing |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BXI1 |
YNL305C |
Protein involved in apoptosis |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PAL2 |
YHR097C |
Protein involved in clathrin-mediated endocytosis |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RGI1 |
YER067W |
Protein involved in energy metabolism under respiratory conditions |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RIM11 |
YMR139W |
Protein kinase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PHM6 |
YDR281C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MSC3 |
YLR219W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YKR018C |
YKR018C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YDR222W |
YDR222W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RCN2 |
YOR220W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CUE4 |
YML101C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PNS1 |
YOR161C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
northern blot evidence |
GFD2 |
YCL036W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YOL019W-A |
YOL019W-A |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YER034W |
YER034W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ICY1 |
YMR195W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YOR062C |
YOR062C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YPR159C-A |
YPR159C-A |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YMR295C |
YMR295C |
Protein of unknown function that associates with ribosomes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YBR062C |
YBR062C |
Protein of unknown function that interacts with Msb2p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
IGO2 |
YHR132W-A |
Protein required for initiation of G0 program |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
EFR3 |
YMR212C |
Protein required for Stt4-containing PI kinase complex localization |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MRX3 |
YBL095W |
Protein that associates with mitochondrial ribosome |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RFU1 |
YLR073C |
Protein that inhibits Doa4p deubiquitinating activity |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
VMA22 |
YHR060W |
Protein that is required for vacuolar H+-ATPase (V-ATPase) function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MGM101 |
YJR144W |
Protein with a role in mitochondrial DNA recombinational repair |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RDL2 |
YOR286W |
Protein with rhodanese activity |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
THI22 |
YPR121W |
Protein with similarity to hydroxymethylpyrimidine phosphate kinases |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SMN1 |
YHR202W |
Putative AMP hydrolase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ATR2 |
YMR279C |
Putative boron transporter involved in boron efflux and resistance |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MST28 |
YAR033W |
Putative integral membrane protein, involved in vesicle formation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
VTH2 |
YJL222W |
Putative membrane glycoprotein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
VTH1 |
YIL173W |
Putative membrane glycoprotein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YMD8 |
YML038C |
Putative nucleotide sugar transporter |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YLR361C-A |
YLR361C-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YLR264C-A |
YLR264C-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YMR105W-A |
YMR105W-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAR035C-A |
YAR035C-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YNR068C |
YNR068C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YJR149W |
YJR149W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YGR117C |
YGR117C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YBR090C |
YBR090C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YMR253C |
YMR253C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YOR292C |
YOR292C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YDR169C-A |
YDR169C-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YDR182W-A |
YDR182W-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YML003W |
YML003W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ECM12 |
YHR021W-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YOL014W |
YOL014W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YBR225W |
YBR225W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FMP23 |
YBR047W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YJR098C |
YJR098C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YBR285W |
YBR285W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YJR115W |
YJR115W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RIM4 |
YHL024W |
Putative RNA-binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PDX3 |
YBR035C |
Pyridoxine (pyridoxamine) phosphate oxidase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PYC1 |
YGL062W |
Pyruvate carboxylase isoform |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
STE3 |
YKL178C |
Receptor for a factor pheromone |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SRF1 |
YDL133W |
Regulator of phospholipase D (Spo14p) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YHR214C-B |
YHR214C-B |
Retrotransposon TYA Gag and TYB Pol genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GIC2 |
YDR309C |
Rho-family GTPase interacting protein and Cdc42p effector |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RBK1 |
YCR036W |
Ribokinase, phosphorylates ribose to ribose-5-phosphate |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RNH1 |
YMR234W |
Ribonuclease H1 |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RKI1 |
YOR095C |
Ribose-5-phosphate ketol-isomerase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL11A |
YPR102C |
Ribosomal 60S subunit protein L11A |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL11B |
YGR085C |
Ribosomal 60S subunit protein L11B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL13A |
YDL082W |
Ribosomal 60S subunit protein L13A |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL13B |
YMR142C |
Ribosomal 60S subunit protein L13B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
regulation |
1 |
1 |
1 |
northern blot evidence |
RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL17A |
YKL180W |
Ribosomal 60S subunit protein L17A |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL20A |
YMR242C |
Ribosomal 60S subunit protein L20A |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL20B |
YOR312C |
Ribosomal 60S subunit protein L20B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL26B |
YGR034W |
Ribosomal 60S subunit protein L26B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL27A |
YHR010W |
Ribosomal 60S subunit protein L27A |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL31B |
YLR406C |
Ribosomal 60S subunit protein L31B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL43B |
YJR094W-A |
Ribosomal 60S subunit protein L43B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL7B |
YPL198W |
Ribosomal 60S subunit protein L7B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RKM3 |
YBR030W |
Ribosomal lysine methyltransferase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPS17B |
YDR447C |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
PPZ2 |
YDR436W |
Serine/threonine protein phosphatase Z, isoform of Ppz1p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CPA1 |
YOR303W |
Small subunit of carbamoyl phosphate synthetase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SUR2 |
YDR297W |
Sphinganine C4-hydroxylase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
LAM4 |
YHR080C |
Sterol-binding protein that localizes to puncta in the cortical ER |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GID8 |
YMR135C |
Subunit of GID Complex, binds strongly to central component Vid30p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TFC3 |
YAL001C |
Subunit of RNA polymerase III transcription initiation factor complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC26 |
YFR036W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
KRE29 |
YER038C |
Subunit of the SMC5-SMC6 complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SSH1 |
YBR283C |
Subunit of the Ssh1 translocon complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SRX1 |
YKL086W |
Sulfiredoxin |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
regulation |
1 |
1 |
1 |
northern blot evidence |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC21 |
YOR074C |
Thymidylate synthase |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
PUT3 |
YKL015W |
Transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NRM1 |
YNR009W |
Transcriptional co-repressor of MBF-regulated gene expression |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NRG2 |
YBR066C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MOT3 |
YMR070W |
Transcriptional repressor, activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
STP2 |
YHR006W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
INO2 |
YDR123C |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TRP5 |
YGL026C |
Tryptophan synthase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SEC9 |
YGR009C |
t-SNARE protein required for secretory vesicle-plasma membrane fusion |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ATG27 |
YJL178C |
Type I membrane protein involved in autophagy and the Cvt pathway |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UNG1 |
YML021C |
Uracil-DNA glycosylase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
VMR1 |
YHL035C |
Vacuolar membrane protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CAT8 |
YMR280C |
Zinc cluster transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Negative Genetic |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE1 |
YLR007W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIS3 |
YOL021C |
Exosome core complex catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Negative Genetic |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Positive Genetic |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CDC45 |
YLR103C |
DNA replication initiation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG26 |
YGL001C |
C-3 sterol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
CPR1 |
YDR155C |
Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BDF2 |
YDL070W |
Protein involved in transcription initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ESC8 |
YOL017W |
Protein involved in telomeric and mating-type locus silencing |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRP49 |
YKL167C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
FYV4 |
YHR059W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG3 |
YNR007C |
E2-like enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUM2 |
YBR057C |
Protein essential for meiotic DNA replication and sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP2 |
YNR052C |
Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BLM10 |
YFL007W |
Proteasome activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP31 |
YGR091W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CWC22 |
YGR278W |
Spliceosome-associated protein that is required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NRD1 |
YNL251C |
RNA-binding subunit of Nrd1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP14 |
YDL148C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Positive Genetic |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
RPL17A |
YKL180W |
Ribosomal 60S subunit protein L17A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL33A |
YPL143W |
Ribosomal 60S subunit protein L33A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
WHI5 |
YOR083W |
Repressor of G1 transcription |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
physical |
1 |
1 |
1 |
Co-localization |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TOS4 |
YLR183C |
Putative transcription factor, contains Forkhead Associated domain |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TOS4 |
YLR183C |
Putative transcription factor, contains Forkhead Associated domain |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SKT5 |
YBL061C |
Activator of Chs3p (chitin synthase III) during vegetative growth |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SEY1 |
YOR165W |
Dynamin-like GTPase that mediates homotypic ER fusion |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SGM1 |
YJR134C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SSM4 |
YIL030C |
Membrane-embedded ubiquitin-protein ligase and retrotranslocase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPR148C |
YPR148C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RTN1 |
YDR233C |
Reticulon protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
THP1 |
YOL072W |
Nuclear pore-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS75 |
YNL246W |
NAP family histone chaperone |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWC7 |
YLR385C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP2 |
YOR124C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPL113C |
YPL113C |
Glyoxylate reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRP40 |
YKR092C |
Nucleolar serine-rich protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Positive Genetic |
SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YBR287W |
YBR287W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Lethality |
VAC17 |
YCL063W |
Phosphoprotein involved in vacuole inheritance |
genetic |
1 |
1 |
1 |
Dosage Lethality |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFT2 |
YBL102W |
Tetra-spanning membrane protein found mostly in the late Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
VHC1 |
YBR235W |
Vacuolar membrane cation-chloride cotransporter (CCC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDL157C |
YDL157C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMN3 |
YER113C |
Protein with a role in cellular adhesion and filamentous growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR210C |
YGR210C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLI1 |
YGR212W |
N-acetyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
genetic |
1 |
1 |
1 |
Positive Genetic |
TCD1 |
YHR003C |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
WSS1 |
YHR134W |
SUMO-ligase and SUMO-targeted metalloprotease |
genetic |
1 |
1 |
1 |
Positive Genetic |
TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGN1 |
YIR001C |
Cytoplasmic RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFG1 |
YOR315W |
Nuclear protein putative transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB3 |
YDR169C |
Ribosomal RNA processing element (RRPE)-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RRN5 |
YLR141W |
Protein involved in transcription of rDNA by RNA polymerase I |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RRN9 |
YMR270C |
Protein involved in promoting high level transcription of rDNA |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
UAF30 |
YOR295W |
Subunit of UAF (upstream activation factor) complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TBS1 |
YBR150C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
THI2 |
YBR240C |
Transcriptional activator of thiamine biosynthetic genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SKO1 |
YNL167C |
Basic leucine zipper transcription factor of the ATF/CREB family |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPS1 |
YLR120C |
Aspartic protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
USV1 |
YPL230W |
Putative transcription factor containing a C2H2 zinc finger |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSF2 |
YJR127C |
Zinc-finger protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPK3 |
YBR028C |
AGC kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOD6 |
YBL054W |
PAC motif binding protein involved in rRNA and ribosome biogenesis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SML1 |
YML058W |
Ribonucleotide reductase inhibitor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
STN1 |
YDR082W |
Telomere end-binding and capping protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
UTP5 |
YDR398W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
UTP6 |
YDR449C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJU2 |
YKL095W |
Essential protein required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
UTP15 |
YMR093W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Positive Genetic |
SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNX4 |
YJL036W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Positive Genetic |
VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPP381 |
YBR152W |
mRNA splicing factor, component of U4/U6.U5 tri-snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDA1 |
YGR245C |
Protein required for actin organization and passage through Start |
genetic |
1 |
1 |
1 |
Negative Genetic |
STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF8 |
YML114C |
TFIID subunit (65 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC5 |
YOL034W |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM50 |
YPL063W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHG1 |
YBR258C |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDL206W |
YDL206W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR210W |
YDR210W |
Predicted tail-anchored plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR018C |
YGR018C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLF2 |
YHL014C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TED1 |
YIL039W |
GPI-glycan remodelase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIL067C |
YIL067C |
Uncharacterized protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDP1 |
YIL113W |
Stress-inducible dual-specificity MAP kinase phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIR016W |
YIR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAP185 |
YJL098W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
XPT1 |
YJR133W |
Xanthine-guanine phosphoribosyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL31B |
YLR406C |
Ribosomal 60S subunit protein L31B |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOX1 |
YML027W |
Homeobox transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL140C |
YNL140C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL143C |
YNL143C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZRG17 |
YNR039C |
Endoplasmic reticulum zinc transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL024W |
YOL024W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRL4 |
YPL033C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
1 |
1 |
1 |
Positive Genetic |
YIA6 |
YIL006W |
Mitochondrial NAD+ transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
YVH1 |
YIR026C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDA5 |
YLR426W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Positive Genetic |
URA1 |
YKL216W |
Dihydroorotate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
URA5 |
YML106W |
Major orotate phosphoribosyltransferase (OPRTase) isozyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TUM1 |
YOR251C |
Rhodanese domain sulfur transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMC2 |
YBR104W |
Putative mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO14 |
YKR031C |
Phospholipase D |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBT1 |
YLL048C |
Transporter of the ATP-binding cassette (ABC) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEL1 |
YBL088C |
Protein kinase primarily involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MLH2 |
YLR035C |
Protein involved in mismatch repair and meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
RET3 |
YPL010W |
Zeta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ABF2 |
YMR072W |
Mitochondrial DNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HRK1 |
YOR267C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM25 |
YJL201W |
Endocytic site protein required for stress-induced cell elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEM13 |
YDR044W |
Coproporphyrinogen III oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
DIM1 |
YPL266W |
Essential 18S rRNA dimethylase (dimethyladenosine transferase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
DOT6 |
YER088C |
Protein involved in rRNA and ribosome biogenesis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPR3 |
YML074C |
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
FOL2 |
YGR267C |
GTP-cyclohydrolase I, catalyzes first step in folic acid biosynthesis |
genetic |
1 |
1 |
1 |
Dosage Lethality |
ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
CNB1 |
YKL190W |
Calcineurin B |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Positive Genetic |
GRR1 |
YJR090C |
F-box protein component of an SCF ubiquitin-ligase complex |
genetic |
1 |
1 |
1 |
Dosage Lethality |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
GYP6 |
YJL044C |
GTPase-activating protein (GAP) for yeast Rab family member Ypt6p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EGD1 |
YPL037C |
Subunit beta1 of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG42 |
YBR139W |
Vacuolar serine-type carboxypeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYC8 |
YBR112C |
General transcriptional co-repressor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MLH3 |
YPL164C |
Protein involved in DNA mismatch repair and meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMD4 |
YML056C |
Inosine monophosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
genetic |
1 |
1 |
1 |
Dosage Lethality |
FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISU1 |
YPL135W |
Conserved protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Dosage Lethality |
HHO1 |
YPL127C |
Histone H1, linker histone with roles in meiosis and sporulation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CDC123 |
YLR215C |
Assembly factor for the eIF2 translation initiation factor complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUD7 |
YOR299W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MKK2 |
YPL140C |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCK2 |
YER167W |
Serine/threonine-rich protein involved in PKC1 signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ILV2 |
YMR108W |
Acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICP55 |
YER078C |
Mitochondrial aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIH1 |
YMR036C |
Protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
AHC1 |
YOR023C |
Subunit of the Ada histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAS2 |
YHR024C |
Alpha subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CPR3 |
YML078W |
Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MMS4 |
YBR098W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSG5 |
YNL053W |
Dual-specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Positive Genetic |
FCF1 |
YDR339C |
PINc domain endonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIM11 |
YMR139W |
Protein kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
CHZ1 |
YER030W |
Histone chaperone for Htz1p/H2A-H2B dimer |
genetic |
1 |
1 |
1 |
Negative Genetic |
NTA1 |
YJR062C |
Amidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CRC1 |
YOR100C |
Mitochondrial inner membrane carnitine transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RHO4 |
YKR055W |
Non-essential small GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIT2 |
YBR270C |
Subunit of TORC2 membrane-associated complex |
genetic |
1 |
1 |
1 |
Dosage Lethality |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARG81 |
YML099C |
Zinc finger transcription factor involved in arginine-responsive genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
GRX5 |
YPL059W |
Glutathione-dependent oxidoreductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GZF3 |
YJL110C |
GATA zinc finger protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
BSC5 |
YNR069C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Lethality |
NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IKS1 |
YJL057C |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP5 |
YBR237W |
RNA helicase in the DEAD-box family |
genetic |
1 |
1 |
1 |
Positive Genetic |
MND2 |
YIR025W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
GNP1 |
YDR508C |
Broad specificity amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
QCR6 |
YFR033C |
Subunit 6 of the ubiquinol cytochrome-c reductase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
PEF1 |
YGR058W |
Penta-EF-hand protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPN2 |
YOR262W |
Putative GTPase with a specific role in RNA pol II and polIII biogenes |
genetic |
1 |
1 |
1 |
Positive Genetic |
OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOC1 |
YGL240W |
Processivity factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
genetic |
1 |
1 |
1 |
Negative Genetic |
AMD1 |
YML035C |
AMP deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
MIF2 |
YKL089W |
Centromeric CDEIII region binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RIF1 |
YBR275C |
Protein involved in control of DNA replication |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
HOS1 |
YPR068C |
Class I histone deacetylase (HDAC) family member |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
MTH1 |
YDR277C |
Negative regulator of the glucose-sensing signal transduction pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATS1 |
YAL020C |
Protein required for modification of wobble nucleosides in tRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
NYV1 |
YLR093C |
v-SNARE component of the vacuolar SNARE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRK1 |
YIL095W |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD17 |
YOR368W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Positive Genetic |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARG80 |
YMR042W |
Transcription factor involved in regulating arginine-responsive genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARG82 |
YDR173C |
Inositol polyphosphate multikinase (IPMK) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FBP26 |
YJL155C |
Fructose-2,6-bisphosphatase, required for glucose metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET28 |
YIR017C |
bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDR5 |
YOR153W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
GYL1 |
YMR192W |
Putative GTPase activating protein (GAP) with a role in exocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
AZF1 |
YOR113W |
Zinc-finger transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
MIX17 |
YMR002W |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASH1 |
YKL185W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
EIS1 |
YMR031C |
Component of the eisosome required for proper eisosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASN1 |
YPR145W |
Asparagine synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDR1 |
YGL013C |
Transcription factor that regulates the pleiotropic drug response |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NOP8 |
YOL144W |
Nucleolar protein required for 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
PER33 |
YLR064W |
Protein that localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET127 |
YOR017W |
Protein with a role in 5'-end processing of mitochondrial RNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
MHP1 |
YJL042W |
Microtubule-associated protein involved in microtubule organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRG1 |
YHR209W |
S-AdoMet-dependent methyltransferase involved in lipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMP27 |
YLR454W |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLR1 |
YPL091W |
Cytosolic and mitochondrial glutathione oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALG1 |
YBR110W |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AGP2 |
YBR132C |
Plasma membrane regulator of polyamine and carnitine transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
GLO4 |
YOR040W |
Mitochondrial glyoxalase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLG1 |
YKR058W |
Glycogenin glucosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BNA1 |
YJR025C |
3-hydroxyanthranilic acid dioxygenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIG2 |
YCR089W |
Cell wall adhesin, expressed specifically during mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA4 |
YCR095C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRP35 |
YNL122C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IZH3 |
YLR023C |
Membrane protein involved in zinc ion homeostasis |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
COQ6 |
YGR255C |
Flavin-dependent monooxygenase involved in ubiquinone biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COQ6 |
YGR255C |
Flavin-dependent monooxygenase involved in ubiquinone biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
FLO11 |
YIR019C |
GPI-anchored cell surface glycoprotein (flocculin) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NPT1 |
YOR209C |
Nicotinate phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALD4 |
YOR374W |
Mitochondrial aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUP9 |
YPL177C |
Homeodomain-containing transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
EGH1 |
YIR007W |
Steryl-beta-glucosidase with broad specificity for aglycones |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
FOL3 |
YMR113W |
Dihydrofolate synthetase, involved in folic acid biosynthesis |
genetic |
1 |
1 |
1 |
Dosage Lethality |
PRI2 |
YKL045W |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISR1 |
YPR106W |
Predicted protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC5 |
YFR038W |
Putative ATPase containing the DEAD/H helicase-related sequence motif |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
DAP2 |
YHR028C |
Dipeptidyl aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OTU2 |
YHL013C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAD4 |
YDL243C |
Putative aryl-alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGS2 |
YOR107W |
Negative regulator of glucose-induced cAMP signaling |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTM1 |
YGR257C |
Mitochondrial protein of the mitochondrial carrier family |
genetic |
1 |
1 |
1 |
Positive Genetic |
PKH3 |
YDR466W |
Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
MNN5 |
YJL186W |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DCR2 |
YLR361C |
Protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ2 |
YNR041C |
Para hydroxybenzoate polyprenyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PNC1 |
YGL037C |
Nicotinamidase that converts nicotinamide to nicotinic acid |
genetic |
1 |
1 |
1 |
Negative Genetic |
PNP1 |
YLR209C |
Purine nucleoside phosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAR1 |
YMR171C |
Specificity factor required for Rsp5p-dependent ubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDR3 |
YBL005W |
Transcriptional activator of the pleiotropic drug resistance network |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
KIP3 |
YGL216W |
Kinesin-related antiparallel sliding motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO1 |
YJL153C |
Inositol-3-phosphate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDS1 |
YBR029C |
Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
DAT1 |
YML113W |
DNA binding protein that recognizes oligo(dA).oligo(dT) tracts |
genetic |
1 |
1 |
1 |
Negative Genetic |
QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMC1 |
YIL098C |
Mitochondrial matrix protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MDL2 |
YPL270W |
Mitochondrial inner membrane half-type ABC transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
CYT2 |
YKL087C |
Cytochrome c1 heme lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSM1 |
YGR171C |
Mitochondrial methionyl-tRNA synthetase (MetRS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM34 |
YHL043W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAT3 |
YLR013W |
Protein containing GATA family zinc finger motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
1 |
1 |
1 |
Positive Genetic |
ROT2 |
YBR229C |
Glucosidase II catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET8 |
YNL003C |
S-adenosylmethionine transporter of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM33 |
YML087C |
Protein of unknown function, highly conserved across species |
genetic |
1 |
1 |
1 |
Positive Genetic |
HMI1 |
YOL095C |
Mitochondrial inner membrane localized ATP-dependent DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO3 |
YBR092C |
Constitutively expressed acid phosphatase similar to Pho5p |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRX8 |
YDR336W |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTC4 |
YBR255W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
FMT1 |
YBL013W |
Methionyl-tRNA formyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA6 |
YDR067C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
OAF3 |
YKR064W |
Putative transcriptional repressor with Zn(2)-Cys(6) finger |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUL3 |
YNR062C |
Putative pulcherrimin transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAN2 |
YNR073C |
Mannitol dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |