Standard name Systematic name Name description Description
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p Guanine nucleotide exchange factor for the GTPase Gtr1p; subunit of the HOPS endocytic tethering complex; vacuole membrane protein; functions as a Rab GTPase effector, interacting with both GTP- and GDP-bound conformations of Ypt7p; facilitates tethering and promotes membrane fusion events at the late endosome and vacuole; required for both membrane and protein trafficking; component of vacuole-mitochondrion contacts (vCLAMPs) important for lipid transfer between organelles
Visualize the interactome of VAM6
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.062 0.108 0.087
Endosome 0.404 0.104 0.676
Mito 0.151 0.358 0.175
Nucleolus 0.064 NaN 0.076
SpindlePole 0.073 NaN 0.172
Vac/Vac Memb 0.619 0.583 0.341
Nucleus NaN 0.052 NaN

GFP localization & abundance

GFP localization GFP abundance
ambiguous 319

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
VAM6 1 0 0 2 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex physical 24 5 19 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
PEP5 YMR231W Histone E3 ligase, component of CORVET membrane tethering complex physical 15 4 10 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Co-purification, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
VPS33 YLR396C ATP-binding protein that is a subunit of the HOPS and CORVET complexes physical 14 5 11 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
YPT7 YML001W Rab family GTPase physical 14 4 11 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex
VPS16 YPL045W Subunit of the HOPS and the CORVET complexes physical 11 4 9 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PEP3 YLR148W Component of CORVET membrane tethering complex physical 11 4 8 Affinity Capture-Western, Affinity Capture-Western, Co-purification, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 7 3 6 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 7 3 5 Positive Genetic, Positive Genetic, Positive Genetic, Phenotypic Enhancement, Positive Genetic, Positive Genetic, Synthetic Lethality
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 6 3 5 Synthetic Growth Defect, Synthetic Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 6 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein physical 5 3 4 Affinity Capture-Western, Co-purification, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 5 2 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Synthetic Lethality
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 5 3 3 Synthetic Rescue, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS5 YOR069W Nexin-1 homolog genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SYS1 YJL004C Integral membrane protein of the Golgi genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE physical 4 4 3 Affinity Capture-Western, Co-purification, Affinity Capture-MS, Reconstituted Complex
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 4 3 3 Dosage Rescue, Dosage Rescue, Phenotypic Suppression, Synthetic Rescue
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 4 2 3 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MVP1 YMR004W Protein required for sorting proteins to the vacuole genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PHO80 YOL001W Cyclin genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 3 2 3 Negative Genetic, Synthetic Lethality, Negative Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 3 2 3 Synthetic Lethality, Negative Genetic, Synthetic Lethality
VPS8 YAL002W Membrane-binding component of the CORVET complex physical 3 2 2 Two-hybrid, Two-hybrid, Affinity Capture-MS
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
KGD2 YDR148C Dihydrolipoyl transsuccinylase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ADE6 YGR061C Formylglycinamidine-ribonucleotide (FGAM)-synthetase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
INO2 YDR123C Transcription factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
OCA2 YNL056W Protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPL9B YNL067W Ribosomal 60S subunit protein L9B genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MSN4 YKL062W Stress-responsive transcriptional activator genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SNX3 YOR357C Sorting nexin for late-Golgi enzymes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 2 2 2 Positive Genetic, Synthetic Lethality
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 2 2 2 Co-purification, Affinity Capture-MS
VPS3 YDR495C Component of CORVET membrane tethering complex physical 2 2 2 Two-hybrid, Affinity Capture-MS
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform physical 2 2 2 Affinity Capture-MS, Biochemical Activity
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
SGT1 YOR057W Cochaperone protein genetic 2 2 2 Negative Genetic, Positive Genetic
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex physical 2 2 2 Co-purification, Affinity Capture-Western
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p physical 2 2 2 Two-hybrid, Affinity Capture-MS
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 2 2 2 Positive Genetic, Negative Genetic
INP1 YMR204C Peripheral membrane protein of peroxisomes physical 2 2 2 Affinity Capture-MS, Two-hybrid
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 2 2 2 Positive Genetic, Negative Genetic
MCP1 YOR228C Mitochondrial protein of unknown function involved in lipid homeostas genetic 2 2 2 Phenotypic Suppression, Dosage Rescue
NAN1 YPL126W U3 snoRNP protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases genetic 2 1 2 Negative Genetic, Negative Genetic
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 2 1 2 Positive Genetic, Positive Genetic
CYS4 YGR155W Cystathionine beta-synthase genetic 2 1 2 Negative Genetic, Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 2 1 2 Negative Genetic, Negative Genetic
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 2 1 2 Negative Genetic, Negative Genetic
YPT7 YML001W Rab family GTPase genetic 2 1 2 Positive Genetic, Positive Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 2 1 2 Positive Genetic, Positive Genetic
XDJ1 YLR090W Chaperone with a role in facilitating mitochondrial protein import physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 2 1 2 Negative Genetic, Negative Genetic
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 2 1 2 Positive Genetic, Positive Genetic
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 2 1 2 Negative Genetic, Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 2 1 2 Negative Genetic, Negative Genetic
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CTR1 YPR124W High-affinity copper transporter of plasma membrane genetic 2 1 2 Negative Genetic, Negative Genetic
CYS3 YAL012W Cystathionine gamma-lyase genetic 2 1 2 Negative Genetic, Negative Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 2 Negative Genetic, Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 2 1 2 Negative Genetic, Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 2 1 2 Negative Genetic, Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 2 1 2 Negative Genetic, Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) physical 2 1 2 Two-hybrid, Two-hybrid
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
MHP1 YJL042W Microtubule-associated protein involved in microtubule organization physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GTA1 YEL043W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
GDA1 YEL042W Guanosine diphosphatase located in the Golgi genetic 2 1 2 Negative Genetic, Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
CUE3 YGL110C Subunit of ribosome-associated quality control trigger complex (RQT) genetic 2 1 2 Negative Genetic, Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 2 1 2 Negative Genetic, Negative Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 2 1 2 Positive Genetic, Positive Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 2 1 2 Negative Genetic, Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 1 2 Negative Genetic, Negative Genetic
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 2 1 2 Negative Genetic, Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 2 1 2 Negative Genetic, Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 2 1 2 Negative Genetic, Negative Genetic
MRX11 YPL041C Protein that associates with mitochondrial ribosome genetic 2 1 2 Negative Genetic, Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 1 Positive Genetic, Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic physical 2 2 1 Affinity Capture-Western, Co-purification
PBR1 YNL181W Putative oxidoreductase genetic 2 2 1 Positive Genetic, Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 1 Negative Genetic, Positive Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 2 2 1 Positive Genetic, Negative Genetic
TOM40 YMR203W Component of the TOM (translocase of outer membrane) complex physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 2 2 1 Negative Genetic, Positive Genetic
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 2 1 1 Negative Genetic, Negative Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 2 1 1 Negative Genetic, Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 2 1 1 Positive Genetic, Positive Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 2 1 1 Negative Genetic, Negative Genetic
NOG2 YNR053C Putative GTPase genetic 2 1 1 Negative Genetic, Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 2 1 1 Negative Genetic, Negative Genetic
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 2 1 1 Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 2 1 1 Positive Genetic, Positive Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 2 1 1 Negative Genetic, Negative Genetic
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 2 1 1 Negative Genetic, Negative Genetic
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) genetic 2 1 1 Positive Genetic, Positive Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 2 1 1 Negative Genetic, Negative Genetic
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 2 1 1 Negative Genetic, Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 2 1 1 Negative Genetic, Negative Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CUP2 YGL166W Copper-binding transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation physical 1 1 1 Affinity Capture-MS
CEF1 YMR213W Essential splicing factor genetic 1 1 1 Negative Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs genetic 1 1 1 Negative Genetic
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 1 1 1 Affinity Capture-MS
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-MS
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
RPB2 YOR151C RNA polymerase II second largest subunit B150 physical 1 1 1 Affinity Capture-MS
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 1 1 1 Affinity Capture-MS
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p physical 1 1 1 Affinity Capture-MS
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
IKI3 YLR384C Subunit of Elongator complex physical 1 1 1 Affinity Capture-MS
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Positive Genetic
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Positive Genetic
STT4 YLR305C Phosphatidylinositol-4-kinase physical 1 1 1 Affinity Capture-MS
BRX1 YOL077C Nucleolar protein physical 1 1 1 Affinity Capture-MS
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing physical 1 1 1 Affinity Capture-MS
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing genetic 1 1 1 Negative Genetic
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 1 1 1 Affinity Capture-MS
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly physical 1 1 1 Affinity Capture-MS
ERB1 YMR049C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
HAS1 YMR290C ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
MAK16 YAL025C Essential nuclear protein physical 1 1 1 Affinity Capture-MS
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis physical 1 1 1 Affinity Capture-MS
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 1 1 1 Negative Genetic
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
NOP16 YER002W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase physical 1 1 1 Affinity Capture-MS
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
NOP4 YPL043W Nucleolar protein physical 1 1 1 Affinity Capture-MS
NSA1 YGL111W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
RPL27A YHR010W Ribosomal 60S subunit protein L27A physical 1 1 1 Affinity Capture-MS
RPL30 YGL030W Ribosomal 60S subunit protein L30 physical 1 1 1 Affinity Capture-MS
RPL32 YBL092W Ribosomal 60S subunit protein L32 physical 1 1 1 Affinity Capture-MS
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
SSF1 YHR066W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
GCD6 YDR211W Catalytic epsilon subunit of the translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome physical 1 1 1 Affinity Capture-MS
RSM23 YGL129C Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
IMH1 YLR309C Protein involved in vesicular transport physical 1 1 1 Affinity Capture-MS
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs physical 1 1 1 Affinity Capture-MS
RIX7 YLL034C Putative ATPase of the AAA family physical 1 1 1 Affinity Capture-MS
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
RMP1 YLR145W Subunit of RNase MRP genetic 1 1 1 Negative Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Affinity Capture-MS
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Positive Genetic
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 1 1 1 Affinity Capture-MS
PRP8 YHR165C Component of U4/U6-U5 snRNP complex genetic 1 1 1 Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 1 1 1 Affinity Capture-MS
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
EMW1 YNL313C Essential conserved protein with a role in cell wall integrity physical 1 1 1 Affinity Capture-MS
NOC2 YOR206W Protein involved in ribosome biogenesis physical 1 1 1 Affinity Capture-MS
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes physical 1 1 1 Affinity Capture-MS
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 1 1 1 Affinity Capture-MS
RRP14 YKL082C Essential protein, constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling physical 1 1 1 Affinity Capture-MS
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 1 1 1 Affinity Capture-MS
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus physical 1 1 1 Affinity Capture-MS
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Negative Genetic
DIP2 YLR129W Nucleolar protein physical 1 1 1 Affinity Capture-MS
PWP2 YCR057C Conserved 90S pre-ribosomal component physical 1 1 1 Affinity Capture-MS
UTP13 YLR222C Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation physical 1 1 1 Affinity Capture-MS
UTP21 YLR409C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 1 1 1 Affinity Capture-MS
RRP7 YCL031C Essential protein involved in rRNA processing and ribosome biogenesis physical 1 1 1 Affinity Capture-MS
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-MS
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly physical 1 1 1 Affinity Capture-MS
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
CIC1 YHR052W Essential protein that interacts with proteasome components physical 1 1 1 Affinity Capture-MS
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family physical 1 1 1 Affinity Capture-MS
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs physical 1 1 1 Affinity Capture-MS
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex physical 1 1 1 Affinity Capture-MS
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins physical 1 1 1 Affinity Capture-MS
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
FUN12 YAL035W Translation initiation factor eIF5B physical 1 1 1 Affinity Capture-MS
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
HCA4 YJL033W DEAD box RNA helicase physical 1 1 1 Affinity Capture-MS
MTR4 YJL050W RNA duplex-sensing translocase physical 1 1 1 Affinity Capture-MS
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease physical 1 1 1 Affinity Capture-MS
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase physical 1 1 1 Affinity Capture-MS
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase physical 1 1 1 Affinity Capture-MS
LSM5 YER146W Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
LSM1 YJL124C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-MS
LSM3 YLR438C-A Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
LSM6 YDR378C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-MS
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TMA64 YDR117C Protein of unknown function that associates with ribosomes physical 1 1 1 Affinity Capture-MS
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex physical 1 1 1 Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 1 1 1 Affinity Capture-MS
RRP9 YPR137W Protein involved in pre-rRNA processing physical 1 1 1 Affinity Capture-MS
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
RPB5 YBR154C RNA polymerase subunit ABC27 physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
RPC19 YNL113W RNA polymerase subunit AC19 physical 1 1 1 Affinity Capture-MS
RPC19 YNL113W RNA polymerase subunit AC19 genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
RPO31 YOR116C RNA polymerase III largest subunit C160 physical 1 1 1 Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 1 1 1 Affinity Capture-MS
RPA49 YNL248C RNA polymerase I subunit A49 physical 1 1 1 Affinity Capture-MS
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Negative Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-MS
FMP52 YER004W Protein of unknown function genetic 1 1 1 Negative Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 1 1 1 Affinity Capture-MS
RRB1 YMR131C Specific assembly chaperone for ribosomal protein Rpl3p physical 1 1 1 Affinity Capture-MS
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase physical 1 1 1 Affinity Capture-MS
HPR1 YDR138W Subunit of THO/TREX complexes physical 1 1 1 Affinity Capture-MS
MFT1 YML062C Subunit of the THO complex physical 1 1 1 Affinity Capture-MS
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Positive Genetic
RSC3 YDR303C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase physical 1 1 1 Affinity Capture-MS
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase genetic 1 1 1 Negative Genetic
PRP39 YML046W U1 snRNP protein involved in splicing physical 1 1 1 Affinity Capture-MS
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 1 1 1 Affinity Capture-MS
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing physical 1 1 1 Affinity Capture-MS
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing genetic 1 1 1 Negative Genetic
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
CEX1 YOR112W Component of nuclear aminoacylation-dependent tRNA export pathway genetic 1 1 1 Negative Genetic
UTP9 YHR196W Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
RPN2 YIL075C Subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Positive Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) physical 1 1 1 Affinity Capture-MS
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
PTA1 YAL043C Subunit of holo-CPF genetic 1 1 1 Negative Genetic
IMD2 YHR216W Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
IMD3 YLR432W Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-MS
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
PRE2 YPR103W Beta 5 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
PRE3 YJL001W Beta 1 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Negative Genetic
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex genetic 1 1 1 Negative Genetic
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
LSG1 YGL099W Putative GTPase involved in 60S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-MS
PUF6 YDR496C Pumilio-homology domain protein physical 1 1 1 Affinity Capture-MS
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Affinity Capture-MS
RCL1 YOL010W Endonuclease that cleaves pre-rRNA at site A2 for 18S rRNA biogenesis physical 1 1 1 Affinity Capture-MS
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA physical 1 1 1 Affinity Capture-MS
THS1 YIL078W Threonyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling physical 1 1 1 Affinity Capture-MS
URB1 YKL014C Protein required for the normal accumulation of 25S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
HGH1 YGR187C Chaperone protein for translation factor eEF2 physical 1 1 1 Affinity Capture-MS
ABD1 YBR236C Methyltransferase genetic 1 1 1 Negative Genetic
ADE13 YLR359W Adenylosuccinate lyase physical 1 1 1 Affinity Capture-MS
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Positive Genetic
APL1 YJR005W Beta-adaptin physical 1 1 1 Affinity Capture-MS
APL3 YBL037W Alpha-adaptin physical 1 1 1 Affinity Capture-MS
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex physical 1 1 1 Affinity Capture-MS
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA physical 1 1 1 Affinity Capture-MS
ARO1 YDR127W Pentafunctional arom protein physical 1 1 1 Affinity Capture-MS
ARP2 YDL029W Essential component of the Arp2/3 complex physical 1 1 1 Affinity Capture-MS
ARP3 YJR065C Essential component of the Arp2/3 complex physical 1 1 1 Affinity Capture-MS
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Negative Genetic
BEM1 YBR200W Protein containing SH3-domains physical 1 1 1 Co-fractionation
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III physical 1 1 1 Affinity Capture-MS
BEM2 YER155C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Affinity Capture-MS
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 1 1 1 Affinity Capture-MS
CDC10 YCR002C Component of the septin ring, required for cytokinesis physical 1 1 1 Affinity Capture-MS
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC45 YLR103C DNA replication initiation factor genetic 1 1 1 Positive Genetic
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) physical 1 1 1 Affinity Capture-MS
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
NSA2 YER126C Protein constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
TIF6 YPR016C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SDA1 YGR245C Protein required for actin organization and passage through Start physical 1 1 1 Affinity Capture-MS
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes physical 1 1 1 Affinity Capture-MS
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Negative Genetic
IPI3 YNL182C Component of the Rix1 complex and pre-replicative complexes (pre-RCs) physical 1 1 1 Affinity Capture-MS
IPI3 YNL182C Component of the Rix1 complex and pre-replicative complexes (pre-RCs) genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase physical 1 1 1 Affinity Capture-MS
CHC1 YGL206C Clathrin heavy chain physical 1 1 1 Affinity Capture-MS
CIP1 YPL014W Cyclin-dependent kinase inhibitor physical 1 1 1 Affinity Capture-MS
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex physical 1 1 1 Affinity Capture-MS
CYR1 YJL005W Adenylate cyclase physical 1 1 1 Affinity Capture-MS
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Phenotypic Enhancement
EMG1 YLR186W Methyltransferase for rRNA genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
FAP1 YNL023C Protein that binds to Fpr1p physical 1 1 1 Affinity Capture-MS
FRS1 YLR060W Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
GTR2 YGR163W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
AEP1 YMR064W Protein required for expression of the mitochondrial OLI1 gene physical 1 1 1 Affinity Capture-MS
AEP2 YMR282C Mitochondrial protein physical 1 1 1 Affinity Capture-MS
ATP22 YDR350C Specific translational activator for the mitochondrial ATP6 mRNA genetic 1 1 1 Negative Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 1 1 1 Affinity Capture-MS
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor physical 1 1 1 Affinity Capture-MS
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Negative Genetic
UTP20 YBL004W Component of the small-subunit (SSU) processome physical 1 1 1 Affinity Capture-MS
UTP7 YER082C Nucleolar protein physical 1 1 1 Affinity Capture-MS
HSL1 YKL101W Nim1p-related protein kinase physical 1 1 1 Affinity Capture-MS
IMP3 YHR148W Component of the SSU processome physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
GEA2 YEL022W Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) physical 1 1 1 Affinity Capture-MS
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
LSM2 YBL026W Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
LSM4 YER112W Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
LSM7 YNL147W Lsm (Like Sm) protein physical 1 1 1 Two-hybrid
LST8 YNL006W Protein required for the transport of Gap1p physical 1 1 1 Affinity Capture-MS
MAK5 YBR142W Essential nucleolar protein physical 1 1 1 Affinity Capture-MS
MAS1 YLR163C Beta subunit of the mitochondrial processing protease (MPP) genetic 1 1 1 Negative Genetic
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) physical 1 1 1 Affinity Capture-MS
MCM6 YGL201C Protein involved in DNA replication physical 1 1 1 Affinity Capture-MS
COG3 YER157W Essential component of the conserved oligomeric Golgi complex physical 1 1 1 Affinity Capture-MS
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
ADA2 YDR448W Transcription coactivator physical 1 1 1 Affinity Capture-MS
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase physical 1 1 1 Affinity Capture-MS
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Positive Genetic
MRP4 YHL004W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 1 1 1 Affinity Capture-MS
IMG1 YCR046C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRP7 YNL005C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRM1 YOR201C Ribose methyltransferase physical 1 1 1 Affinity Capture-MS
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL16 YBL038W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRP49 YKL167C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL25 YGR076C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL28 YDR462W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL4 YLR439W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL7 YDR237W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL9 YGR220C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRH4 YGL064C Mitochondrial ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
MRPS28 YDR337W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
MRPS18 YNL306W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis physical 1 1 1 Affinity Capture-MS
MSH2 YOL090W Protein that binds to DNA mismatches physical 1 1 1 Affinity Capture-MS
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Negative Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member physical 1 1 1 Affinity Capture-MS
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair physical 1 1 1 Affinity Capture-MS
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation physical 1 1 1 Affinity Capture-MS
MLC1 YGL106W Essential light chain for Myo1p physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring physical 1 1 1 Affinity Capture-MS
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase physical 1 1 1 Affinity Capture-MS
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
FPR4 YLR449W Peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Positive Genetic
MRPL15 YLR312W-A Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL3 YMR024W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex physical 1 1 1 Affinity Capture-MS
OST1 YJL002C Alpha subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member physical 1 1 1 Affinity Capture-MS
DUR12 YBR208C Urea amidolyase physical 1 1 1 Affinity Capture-MS
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation physical 1 1 1 Affinity Capture-MS
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A physical 1 1 1 Affinity Capture-MS
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
MDS3 YGL197W Putative component of the TOR regulatory pathway physical 1 1 1 Affinity Capture-MS
PTC3 YBL056W Type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
PAA1 YDR071C Polyamine acetyltransferase physical 1 1 1 Affinity Capture-MS
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon physical 1 1 1 Affinity Capture-MS
NAB6 YML117W Putative RNA-binding protein physical 1 1 1 Affinity Capture-MS
DBP8 YHR169W ATPase, putative RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
RAD23 YEL037C Protein with ubiquitin-like N terminus genetic 1 1 1 Negative Genetic
CPA2 YJR109C Large subunit of carbamoyl phosphate synthetase physical 1 1 1 Affinity Capture-MS
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p physical 1 1 1 Affinity Capture-MS
RAI1 YGL246C Nuclear decapping endonuclease physical 1 1 1 Affinity Capture-MS
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) physical 1 1 1 Affinity Capture-MS
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
RFC3 YNL290W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes genetic 1 1 1 Negative Genetic
FYV8 YGR196C Protein of unknown function physical 1 1 1 Affinity Capture-MS
RFA3 YJL173C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
RPA12 YJR063W RNA polymerase I subunit A12.2 physical 1 1 1 Affinity Capture-MS
RPB11 YOL005C RNA polymerase II subunit B12.5 physical 1 1 1 Affinity Capture-MS
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes physical 1 1 1 Affinity Capture-MS
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A physical 1 1 1 Affinity Capture-MS
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
RPN13 YLR421C Subunit of the 19S regulatory particle of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Negative Genetic
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) physical 1 1 1 Affinity Capture-MS
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase physical 1 1 1 Affinity Capture-MS
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) physical 1 1 1 Affinity Capture-MS
SEC21 YNL287W Gamma subunit of coatomer physical 1 1 1 Affinity Capture-MS
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer physical 1 1 1 Affinity Capture-MS
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 1 1 1 Affinity Capture-MS
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 1 1 1 Negative Genetic
SGN1 YIR001C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-MS
RIE1 YGR250C RNA binding protein and negative regulator of START physical 1 1 1 Affinity Capture-MS
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p physical 1 1 1 Affinity Capture-MS
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex physical 1 1 1 Affinity Capture-MS
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
BGL2 YGR282C Endo-beta-1,3-glucanase genetic 1 1 1 Negative Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor physical 1 1 1 Affinity Capture-MS
AVT4 YNL101W Vacuolar transporter physical 1 1 1 Affinity Capture-MS
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 1 1 1 Dosage Rescue
SLA1 YBL007C Cytoskeletal protein binding protein physical 1 1 1 Affinity Capture-MS
SMC1 YFL008W Subunit of the multiprotein cohesin complex physical 1 1 1 Affinity Capture-MS
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
SMC3 YJL074C Subunit of the multiprotein cohesin complex physical 1 1 1 Affinity Capture-MS
SMD1 YGR074W Core Sm protein Sm D1 physical 1 1 1 Affinity Capture-MS
RSE1 YML049C Protein involved in pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
SMD2 YLR275W Core Sm protein Sm D2 physical 1 1 1 Affinity Capture-MS
SME1 YOR159C Core Sm protein Sm E genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Affinity Capture-MS
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA physical 1 1 1 Affinity Capture-MS
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
SPO7 YAL009W Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme physical 1 1 1 Affinity Capture-MS
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Positive Genetic
SRB6 YBR253W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
SEC65 YML105C Subunit of the signal recognition particle (SRP) physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-MS
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) physical 1 1 1 Affinity Capture-MS
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 1 1 1 Affinity Capture-MS
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase physical 1 1 1 Affinity Capture-MS
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Negative Genetic
MRPL23 YOR150W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
SUI3 YPL237W Beta subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p physical 1 1 1 Affinity Capture-MS
SEN54 YPL083C Subunit of the tRNA splicing endonuclease physical 1 1 1 Affinity Capture-MS
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
TAF3 YPL011C TFIID subunit (47 kDa) physical 1 1 1 Affinity Capture-MS
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-MS
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
RBG1 YAL036C Member of the DRG family of GTP-binding proteins physical 1 1 1 Affinity Capture-MS
TKL1 YPR074C Transketolase physical 1 1 1 Affinity Capture-MS
LTE1 YAL024C Protein similar to GDP/GTP exchange factors physical 1 1 1 Affinity Capture-MS
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
GLN1 YPR035W Glutamine synthetase (GS) physical 1 1 1 Affinity Capture-MS
GLN1 YPR035W Glutamine synthetase (GS) genetic 1 1 1 Negative Genetic
TRP2 YER090W Anthranilate synthase genetic 1 1 1 Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
TRS120 YDR407C Component of transport protein particle (TRAPP) complex II physical 1 1 1 Affinity Capture-MS
TRS130 YMR218C Component of transport protein particle (TRAPP) complex II physical 1 1 1 Affinity Capture-MS
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis physical 1 1 1 Affinity Capture-MS
ECM30 YLR436C Protein of unknown function physical 1 1 1 Affinity Capture-MS
SEC3 YER008C Subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Affinity Capture-MS
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
PEP5 YMR231W Histone E3 ligase, component of CORVET membrane tethering complex genetic 1 1 1 Synthetic Lethality
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity physical 1 1 1 Co-purification
VPS3 YDR495C Component of CORVET membrane tethering complex genetic 1 1 1 Phenotypic Enhancement
VPS21 YOR089C Endosomal Rab family GTPase physical 1 1 1 Two-hybrid
YPT52 YKR014C Endosomal Rab family GTPase physical 1 1 1 Two-hybrid
YPT6 YLR262C Rab family GTPase physical 1 1 1 Two-hybrid
YPT11 YNL304W Rab GTPase physical 1 1 1 Two-hybrid
YPT32 YGL210W Rab family GTPase involved in the exocytic pathway physical 1 1 1 Two-hybrid
YPL150W YPL150W Protein kinase of unknown cellular role physical 1 1 1 Affinity Capture-MS
YPL225W YPL225W Protein of unknown function physical 1 1 1 Affinity Capture-MS
YPK3 YBR028C AGC kinase physical 1 1 1 Affinity Capture-MS
YLR419W YLR419W Putative helicase with limited sequence similarity to human Rb protein physical 1 1 1 Affinity Capture-MS
YLL032C YLL032C Protein of unknown function physical 1 1 1 Affinity Capture-MS
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation physical 1 1 1 Affinity Capture-MS
YRF1-2 YER190W Helicase encoded by the Y' element of subtelomeric regions physical 1 1 1 Affinity Capture-MS
YPR202W YPR202W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
YGL036W YGL036W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YRF1-6 YNL339C Helicase encoded by the Y' element of subtelomeric regions physical 1 1 1 Affinity Capture-MS
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex physical 1 1 1 Affinity Capture-MS
YDR514C YDR514C Protein of unknown function that localizes to mitochondria physical 1 1 1 Affinity Capture-MS
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent physical 1 1 1 Affinity Capture-MS
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
YBR138C YBR138C Cytoplasmic protein of unknown function physical 1 1 1 Affinity Capture-MS
YDR338C YDR338C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YBR238C YBR238C Mitochondrial membrane protein physical 1 1 1 Affinity Capture-MS
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 1 1 1 Affinity Capture-MS
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
YPL257W-B YPL257W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YKL075C YKL075C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
VID27 YNL212W Cytoplasmic protein of unknown function physical 1 1 1 Affinity Capture-MS
YDR341C YDR341C Arginyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins physical 1 1 1 Affinity Capture-MS
VNX1 YNL321W Calcium/H+ antiporter localized to the endoplasmic reticulum membrane physical 1 1 1 Affinity Capture-MS
VAS1 YGR094W Mitochondrial and cytoplasmic valyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
WTM1 YOR230W Transcriptional modulator physical 1 1 1 Affinity Capture-MS
YGR237C YGR237C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YVC1 YOR087W Vacuolar cation channel physical 1 1 1 Affinity Capture-MS
YGL117W YGL117W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YHR131C YHR131C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YPL077C YPL077C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis physical 1 1 1 Affinity Capture-MS
YDJ1 YNL064C Type I HSP40 co-chaperone physical 1 1 1 Affinity Capture-MS
YML6 YML025C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
YGR054W YGR054W Eukaryotic initiation factor eIF2A physical 1 1 1 Affinity Capture-MS
YGR054W YGR054W Eukaryotic initiation factor eIF2A genetic 1 1 1 Negative Genetic
YDR239C YDR239C Protein of unknown function physical 1 1 1 Affinity Capture-MS
VHC1 YBR235W Vacuolar membrane cation-chloride cotransporter (CCC) physical 1 1 1 Affinity Capture-MS
YPP1 YGR198W Cargo-transport protein involved in endocytosis physical 1 1 1 Affinity Capture-MS
YPK9 YOR291W Vacuolar protein with a possible role in sequestering heavy metals physical 1 1 1 Affinity Capture-MS
YPK9 YOR291W Vacuolar protein with a possible role in sequestering heavy metals genetic 1 1 1 Phenotypic Enhancement
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 Affinity Capture-MS
ZRT3 YKL175W Vacuolar membrane zinc transporter physical 1 1 1 Affinity Capture-MS
YIL161W YIL161W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
VAN1 YML115C Component of the mannan polymerase I physical 1 1 1 Affinity Capture-MS
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Negative Genetic
YML119W YML119W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Affinity Capture-MS
YSP2 YDR326C Sterol-binding protein physical 1 1 1 Affinity Capture-MS
YCR043C YCR043C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YHB1 YGR234W Nitric oxide oxidoreductase physical 1 1 1 Affinity Capture-MS
YHB1 YGR234W Nitric oxide oxidoreductase genetic 1 1 1 Negative Genetic
YRF1-7 YPL283C Helicase encoded by the Y' element of subtelomeric regions physical 1 1 1 Affinity Capture-MS
YRF1-3 YGR296W Helicase encoded by the Y' element of subtelomeric regions physical 1 1 1 Affinity Capture-MS
YMR1 YJR110W Phosphatidylinositol 3-phosphate (PI3P) phosphatase genetic 1 1 1 Dosage Rescue
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Growth Defect
YGL081W YGL081W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YNR071C YNR071C Putative aldose 1-epimerase genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Negative Genetic
VPS60 YDR486C Protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Positive Genetic
YIR021W-A YIR021W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Positive Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Positive Genetic
YOR186W YOR186W Putative protein of unknown function genetic 1 1 1 Positive Genetic
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Positive Genetic
YPI1 YFR003C Regulatory subunit of the type I protein phosphatase (PP1) Glc7p genetic 1 1 1 Negative Genetic
VRG4 YGL225W Golgi GDP-mannose transporter genetic 1 1 1 Negative Genetic
ZPR1 YGR211W Essential protein with two zinc fingers genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
YDR541C YDR541C Aldehyde reductase genetic 1 1 1 Negative Genetic
YHL048C-A YHL048C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YSC83 YHR017W Non-essential mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
YIL102C YIL102C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YPS6 YIR039C Putative GPI-anchored aspartic protease genetic 1 1 1 Negative Genetic
YJL206C YJL206C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YJR015W YJR015W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKR005C YKR005C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKR018C YKR018C Protein of unknown function genetic 1 1 1 Negative Genetic
YLL053C YLL053C Putative protein genetic 1 1 1 Negative Genetic
YLL056C YLL056C NADH-dependent aldehyde reductase genetic 1 1 1 Negative Genetic
YLR179C YLR179C Protein of unknown function with similarity to Tfs1p genetic 1 1 1 Negative Genetic
YLR407W YLR407W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YMR030W-A YMR030W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YMR099C YMR099C Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) genetic 1 1 1 Negative Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
YOR019W YOR019W Protein of unknown function genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi genetic 1 1 1 Negative Genetic
FUN30 YAL019W Snf2p family member with ATP-dependent chromatin remodeling activity genetic 1 1 1 Negative Genetic
RSM7 YJR113C Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) physical 1 1 1 Affinity Capture-MS
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) genetic 1 1 1 Negative Genetic
LTV1 YKL143W Subunit of the EGO/GSE complex physical 1 1 1 Affinity Capture-MS
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 1 1 1 Affinity Capture-MS
ROK1 YGL171W RNA-dependent ATPase physical 1 1 1 Affinity Capture-MS
LSM12 YHR121W Protein of unknown function that may function in RNA processing physical 1 1 1 Affinity Capture-MS
NTE1 YML059C Serine esterase physical 1 1 1 Affinity Capture-MS
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
SKI3 YPR189W Ski complex component and TPR protein physical 1 1 1 Affinity Capture-MS
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Rescue
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen physical 1 1 1 Affinity Capture-MS
FAR8 YMR029C Protein involved in recovery from arrest in response to pheromone physical 1 1 1 Affinity Capture-MS
FAR7 YFR008W Protein involved in recovery from pheromone-induced cell cycle arrest genetic 1 1 1 Negative Genetic
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor physical 1 1 1 Affinity Capture-MS
PYC2 YBR218C Pyruvate carboxylase isoform physical 1 1 1 Affinity Capture-MS
LAM5 YFL042C Putative sterol transfer protein physical 1 1 1 Affinity Capture-MS
PYC1 YGL062W Pyruvate carboxylase isoform physical 1 1 1 Affinity Capture-MS
HEL2 YDR266C RING finger ubiquitin ligase (E3) physical 1 1 1 Affinity Capture-MS
IRA2 YOL081W GTPase-activating protein physical 1 1 1 Affinity Capture-MS
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Negative Genetic
RNR2 YJL026W Ribonucleotide-diphosphate reductase (RNR), small subunit physical 1 1 1 Affinity Capture-MS
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 1 1 1 Negative Genetic
FOL2 YGR267C GTP-cyclohydrolase I, catalyzes first step in folic acid biosynthesis physical 1 1 1 Affinity Capture-MS
DCS1 YLR270W Non-essential hydrolase involved in mRNA decapping physical 1 1 1 Affinity Capture-MS
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p physical 1 1 1 Affinity Capture-MS
HIR3 YJR140C Subunit of the HIR complex physical 1 1 1 Affinity Capture-MS
DPS1 YLL018C Aspartyl-tRNA synthetase, primarily cytoplasmic physical 1 1 1 Affinity Capture-MS
CDC53 YDL132W Cullin physical 1 1 1 Affinity Capture-MS
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway physical 1 1 1 Affinity Capture-MS
FAA4 YMR246W Long chain fatty acyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
RVS161 YCR009C Amphiphysin-like lipid raft protein physical 1 1 1 Affinity Capture-MS
KOG1 YHR186C Subunit of TORC1 physical 1 1 1 Affinity Capture-MS
KOG1 YHR186C Subunit of TORC1 genetic 1 1 1 Negative Genetic
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p physical 1 1 1 Affinity Capture-MS
PRO1 YDR300C Gamma-glutamyl kinase physical 1 1 1 Affinity Capture-MS
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) physical 1 1 1 Affinity Capture-MS
SEC53 YFL045C Phosphomannomutase physical 1 1 1 Affinity Capture-MS
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) physical 1 1 1 Affinity Capture-MS
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Negative Genetic
PHO81 YGR233C Cyclin-dependent kinase (CDK) inhibitor physical 1 1 1 Affinity Capture-MS
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Negative Genetic
PKH2 YOL100W Serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
GPD2 YOL059W NAD-dependent glycerol 3-phosphate dehydrogenase genetic 1 1 1 Negative Genetic
FAR1 YJL157C CDK inhibitor and nuclear anchor physical 1 1 1 Affinity Capture-MS
TOP2 YNL088W Topoisomerase II physical 1 1 1 Affinity Capture-MS
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone physical 1 1 1 Affinity Capture-MS
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase genetic 1 1 1 Negative Genetic
PCT1 YGR202C Cholinephosphate cytidylyltransferase physical 1 1 1 Affinity Capture-MS
PSR1 YLL010C Plasma membrane-associated protein phosphatase physical 1 1 1 Affinity Capture-MS
DSS1 YMR287C 3'-5' exoribonuclease physical 1 1 1 Affinity Capture-MS
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex physical 1 1 1 Affinity Capture-MS
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Positive Genetic
ACS2 YLR153C Acetyl-coA synthetase isoform physical 1 1 1 Affinity Capture-MS
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Negative Genetic
RNQ1 YCL028W [PIN(+)] prion physical 1 1 1 Affinity Capture-MS
IMD4 YML056C Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
PSK2 YOL045W PAS-domain containing serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
SUV3 YPL029W ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein physical 1 1 1 Affinity Capture-MS
BUL1 YMR275C Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
CDC60 YPL160W Cytosolic leucyl tRNA synthetase physical 1 1 1 Affinity Capture-MS
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase physical 1 1 1 Affinity Capture-MS
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 1 1 1 Affinity Capture-MS
DSS4 YPR017C Guanine nucleotide dissociation stimulator for Sec4p physical 1 1 1 Affinity Capture-MS
SAH1 YER043C S-adenosyl-L-homocysteine hydrolase physical 1 1 1 Affinity Capture-MS
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Negative Genetic
CIN8 YEL061C Bipolar kinesin motor protein physical 1 1 1 Affinity Capture-MS
MAG2 YLR427W Cytoplasmic protein of unknown function physical 1 1 1 Affinity Capture-MS
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis physical 1 1 1 Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
ACS1 YAL054C Acetyl-coA synthetase isoform physical 1 1 1 Affinity Capture-MS
ADE17 YMR120C Enzyme of 'de novo' purine biosynthesis physical 1 1 1 Affinity Capture-MS
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex physical 1 1 1 Affinity Capture-MS
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
IRA1 YBR140C GTPase-activating protein physical 1 1 1 Affinity Capture-MS
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Positive Genetic
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p physical 1 1 1 Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
CCE1 YKL011C Mitochondrial cruciform cutting endonuclease physical 1 1 1 Affinity Capture-MS
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase physical 1 1 1 Affinity Capture-MS
NOP13 YNL175C Nucleolar protein found in preribosomal complexes physical 1 1 1 Affinity Capture-MS
MSS116 YDR194C Mitochondrial transcription elongation factor physical 1 1 1 Affinity Capture-MS
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes physical 1 1 1 Affinity Capture-MS
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 1 1 1 Positive Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 1 1 1 Negative Genetic
MAP2 YBL091C Methionine aminopeptidase physical 1 1 1 Affinity Capture-MS
SKI2 YLR398C Ski complex component and putative RNA helicase physical 1 1 1 Affinity Capture-MS
NOP53 YPL146C Nucleolar protein physical 1 1 1 Affinity Capture-MS
GSY1 YFR015C Glycogen synthase physical 1 1 1 Affinity Capture-MS
LYS1 YIR034C Saccharopine dehydrogenase (NAD+, L-lysine-forming) physical 1 1 1 Affinity Capture-MS
LAA1 YJL207C AP-1 accessory protein physical 1 1 1 Affinity Capture-MS
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Positive Genetic
SAN1 YDR143C Ubiquitin-protein ligase physical 1 1 1 Affinity Capture-MS
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes physical 1 1 1 Affinity Capture-MS
DUT1 YBR252W Deoxyuridine triphosphate diphosphatase (dUTPase) genetic 1 1 1 Negative Genetic
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 1 1 1 Negative Genetic
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit physical 1 1 1 Affinity Capture-MS
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Affinity Capture-MS
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p physical 1 1 1 Affinity Capture-MS
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth physical 1 1 1 Affinity Capture-MS
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Negative Genetic
GBP2 YCL011C Poly(A+) RNA-binding protein physical 1 1 1 Affinity Capture-MS
MDJ1 YFL016C Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity physical 1 1 1 Affinity Capture-MS
ARG1 YOL058W Arginosuccinate synthetase physical 1 1 1 Affinity Capture-MS
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Affinity Capture-MS
ADE6 YGR061C Formylglycinamidine-ribonucleotide (FGAM)-synthetase physical 1 1 1 Affinity Capture-MS
CYS3 YAL012W Cystathionine gamma-lyase physical 1 1 1 Affinity Capture-MS
RRP3 YHR065C Protein involved in rRNA processing physical 1 1 1 Affinity Capture-MS
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein physical 1 1 1 Affinity Capture-MS
MRX1 YER077C Protein that associates with mitochondrial ribosome physical 1 1 1 Affinity Capture-MS
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis physical 1 1 1 Affinity Capture-MS
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Affinity Capture-MS
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p physical 1 1 1 Affinity Capture-MS
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 1 1 1 Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
PKH1 YDR490C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex physical 1 1 1 Affinity Capture-MS
ARO9 YHR137W Aromatic aminotransferase II genetic 1 1 1 Negative Genetic
GDH2 YDL215C NAD(+)-dependent glutamate dehydrogenase physical 1 1 1 Affinity Capture-MS
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 1 1 1 Affinity Capture-MS
APM4 YOL062C Cargo-binding mu subunit of AP-2 physical 1 1 1 Affinity Capture-MS
APL4 YPR029C Gamma-adaptin physical 1 1 1 Affinity Capture-MS
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Positive Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
RHO4 YKR055W Non-essential small GTPase genetic 1 1 1 Negative Genetic
ATP7 YKL016C Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ADH5 YBR145W Alcohol dehydrogenase isoenzyme V genetic 1 1 1 Negative Genetic
STE11 YLR362W Signal transducing MEK kinase physical 1 1 1 Affinity Capture-MS
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 physical 1 1 1 Affinity Capture-MS
PEX29 YDR479C ER-resident protein involved in peroxisomal biogenesis genetic 1 1 1 Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 Affinity Capture-MS
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase physical 1 1 1 Affinity Capture-MS
CIT2 YCR005C Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle physical 1 1 1 Affinity Capture-MS
DAL82 YNL314W Positive regulator of allophanate inducible genes genetic 1 1 1 Negative Genetic
DCI1 YOR180C Peroxisomal protein genetic 1 1 1 Negative Genetic
ENT3 YJR125C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Negative Genetic
FMN1 YDR236C Riboflavin kinase, produces riboflavin monophosphate (FMN) genetic 1 1 1 Negative Genetic
GDH1 YOR375C NADP(+)-dependent glutamate dehydrogenase physical 1 1 1 Affinity Capture-MS
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis physical 1 1 1 Affinity Capture-MS
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex physical 1 1 1 Affinity Capture-Western
MOB2 YFL034C-B Activator of Cbk1p kinase physical 1 1 1 Affinity Capture-MS
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Affinity Capture-MS
ALY2 YJL084C Alpha arrestin, Ub-ligase adaptor for Rsp5p physical 1 1 1 Affinity Capture-MS
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Affinity Capture-MS
IKS1 YJL057C Protein kinase of unknown cellular role physical 1 1 1 Affinity Capture-MS
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 physical 1 1 1 Affinity Capture-MS
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
PDR8 YLR266C Transcription factor genetic 1 1 1 Negative Genetic
RPS26A YGL189C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS26B YER131W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
RMD1 YDL001W Cytoplasmic protein required for sporulation physical 1 1 1 Affinity Capture-MS
GNP1 YDR508C Broad specificity amino acid permease genetic 1 1 1 Negative Genetic
ACF4 YJR083C Protein of unknown function physical 1 1 1 Affinity Capture-MS
PFS1 YHR185C Sporulation protein required for prospore membrane formation genetic 1 1 1 Negative Genetic
NBA1 YOL070C Protein involved in axial bud site selection physical 1 1 1 Affinity Capture-MS
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Growth Defect
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 1 1 1 Affinity Capture-MS
CNL1 YDR357C Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 PCA
ART5 YGR068C Protein proposed to regulate endocytosis of plasma membrane proteins genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins genetic 1 1 1 Negative Genetic
MGL2 YMR210W Monoacylglycerol and triacylglycerol lipase physical 1 1 1 Affinity Capture-MS
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Positive Genetic
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex physical 1 1 1 Affinity Capture-MS
BLI1 YKL061W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 PCA
IBD2 YNL164C Component of the BUB2-dependent spindle checkpoint pathway physical 1 1 1 Affinity Capture-MS
GMH1 YKR030W Golgi membrane protein of unknown function physical 1 1 1 Affinity Capture-MS
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Positive Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex physical 1 1 1 Affinity Capture-MS
ELP3 YPL086C Subunit of Elongator complex physical 1 1 1 Affinity Capture-MS
IPL1 YPL209C Aurora kinase of chromosomal passenger complex physical 1 1 1 Affinity Capture-MS
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 Affinity Capture-MS
DOC1 YGL240W Processivity factor genetic 1 1 1 Negative Genetic
TFC4 YGR047C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis physical 1 1 1 Affinity Capture-MS
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Negative Genetic
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL9A YGL147C Ribosomal 60S subunit protein L9A physical 1 1 1 Affinity Capture-MS
RPL9B YNL067W Ribosomal 60S subunit protein L9B physical 1 1 1 Affinity Capture-MS
RPS24A YER074W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS24B YIL069C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SFH1 YLR321C Component of the RSC chromatin remodeling complex genetic 1 1 1 Phenotypic Suppression
NHP6A YPR052C High-mobility group (HMG) protein physical 1 1 1 Affinity Capture-MS
SMC2 YFR031C Subunit of the condensin complex physical 1 1 1 Affinity Capture-MS
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Positive Genetic
TAF7 YMR227C TFIID subunit (67 kDa) genetic 1 1 1 Negative Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
ARP5 YNL059C Nuclear actin-related protein involved in chromatin remodeling physical 1 1 1 Affinity Capture-MS
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) physical 1 1 1 Affinity Capture-MS
PRP2 YNR011C RNA-dependent DExD/H-box ATPase physical 1 1 1 Affinity Capture-MS
MRS1 YIR021W Splicing protein physical 1 1 1 Affinity Capture-MS
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8B YER102W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL20B YOR312C Ribosomal 60S subunit protein L20B physical 1 1 1 Affinity Capture-MS
RPL20B YOR312C Ribosomal 60S subunit protein L20B genetic 1 1 1 Negative Genetic
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS17B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS1B YML063W Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL22A YLR061W Ribosomal 60S subunit protein L22A physical 1 1 1 Affinity Capture-MS
STE5 YDR103W Pheromone-responsive MAPK scaffold protein physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Positive Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 1 1 1 Affinity Capture-MS
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Positive Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 1 1 1 Negative Genetic
ELO3 YLR372W Elongase genetic 1 1 1 Synthetic Growth Defect
GCD10 YNL062C Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p genetic 1 1 1 Negative Genetic
HXK2 YGL253W Hexokinase isoenzyme 2 physical 1 1 1 Affinity Capture-MS
IOC2 YLR095C Subunit of the Isw1b complex genetic 1 1 1 Positive Genetic
KAR3 YPR141C Minus-end-directed microtubule motor physical 1 1 1 Affinity Capture-MS
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Positive Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export physical 1 1 1 Affinity Capture-MS
MTR2 YKL186C mRNA transport regulator physical 1 1 1 Affinity Capture-MS
MYO3 YKL129C One of two type I myosins physical 1 1 1 Affinity Capture-MS
MYO5 YMR109W One of two type I myosin motors physical 1 1 1 Affinity Capture-MS
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction physical 1 1 1 Affinity Capture-MS
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles physical 1 1 1 Affinity Capture-MS
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Positive Genetic
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion physical 1 1 1 Affinity Capture-MS
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
SIP5 YMR140W Protein of unknown function physical 1 1 1 Affinity Capture-MS
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
TUB4 YLR212C Gamma-tubulin physical 1 1 1 Affinity Capture-MS
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway physical 1 1 1 Affinity Capture-MS
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) physical 1 1 1 Affinity Capture-Western
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation physical 1 1 1 Affinity Capture-MS
BBP1 YPL255W Protein required for the spindle pole body (SPB) duplication physical 1 1 1 Affinity Capture-MS
HRB1 YNL004W Poly(A+) RNA-binding protein physical 1 1 1 Affinity Capture-MS
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Synthetic Lethality
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
SNX4 YJL036W Sorting nexin physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
NAM9 YNL137C Mitochondrial ribosomal component of the small subunit physical 1 1 1 Affinity Capture-MS
PET123 YOR158W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
RSM22 YKL155C Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
RSM10 YDR041W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
RSM18 YER050C Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
BUD8 YLR353W Protein involved in bud-site selection physical 1 1 1 Affinity Capture-MS
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
SNL1 YIL016W Ribosome-associated protein physical 1 1 1 Affinity Capture-MS
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p physical 1 1 1 Affinity Capture-MS
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Positive Genetic
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 1 1 1 Positive Genetic
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis physical 1 1 1 Affinity Capture-MS
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta physical 1 1 1 Affinity Capture-MS
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Positive Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis physical 1 1 1 Affinity Capture-MS
STE50 YCL032W Adaptor protein for various signaling pathways physical 1 1 1 Two-hybrid
BUD6 YLR319C Actin- and formin-interacting protein physical 1 1 1 Affinity Capture-MS
CHS3 YBR023C Chitin synthase III genetic 1 1 1 Negative Genetic
ERG25 YGR060W C-4 methyl sterol oxidase physical 1 1 1 Affinity Capture-MS
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator physical 1 1 1 Affinity Capture-MS
GPB2 YAL056W Multistep regulator of cAMP-PKA signaling physical 1 1 1 Affinity Capture-MS
JEM1 YJL073W DnaJ-like chaperone required for nuclear membrane fusion during mating physical 1 1 1 Affinity Capture-MS
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Dosage Rescue
GAD1 YMR250W Glutamate decarboxylase physical 1 1 1 Affinity Capture-MS
GNT1 YOR320C N-acetylglucosaminyltransferase physical 1 1 1 Affinity Capture-MS
BCH1 YMR237W Member of the ChAPs family (Chs5p-Arf1p-binding proteins) genetic 1 1 1 Negative Genetic
FBP26 YJL155C Fructose-2,6-bisphosphatase, required for glucose metabolism physical 1 1 1 Affinity Capture-MS
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Dosage Growth Defect
DPH6 YLR143W Diphthamide synthetase physical 1 1 1 Affinity Capture-MS
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector physical 1 1 1 Affinity Capture-MS
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
CMR2 YOR093C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p physical 1 1 1 Affinity Capture-MS
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p physical 1 1 1 Affinity Capture-MS
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p genetic 1 1 1 Negative Genetic
SEN2 YLR105C Subunit of the tRNA splicing endonuclease genetic 1 1 1 Negative Genetic
SIP3 YNL257C Putative sterol transfer protein physical 1 1 1 Affinity Capture-MS
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
SPC29 YPL124W Inner plaque spindle pole body (SPB) component physical 1 1 1 Affinity Capture-MS
OSH3 YHR073W Member of an oxysterol-binding protein family physical 1 1 1 Affinity Capture-MS
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
ORC5 YNL261W Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-MS
MGA1 YGR249W Protein similar to heat shock transcription factor genetic 1 1 1 Negative Genetic
SAM2 YDR502C S-adenosylmethionine synthetase physical 1 1 1 Affinity Capture-MS
RPL1A YPL220W Ribosomal 60S subunit protein L1A physical 1 1 1 Affinity Capture-MS
RPL1B YGL135W Ribosomal 60S subunit protein L1B physical 1 1 1 Affinity Capture-MS
RPL1B YGL135W Ribosomal 60S subunit protein L1B genetic 1 1 1 Negative Genetic
PBP1 YGR178C Component of glucose deprivation induced stress granules physical 1 1 1 Affinity Capture-MS
ADY4 YLR227C Structural component of the meiotic outer plaque genetic 1 1 1 Negative Genetic
DFG5 YMR238W Putative mannosidase genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Negative Genetic
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I genetic 1 1 1 Negative Genetic
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) physical 1 1 1 Affinity Capture-MS
PRI1 YIR008C Subunit of DNA primase physical 1 1 1 Affinity Capture-MS
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 1 1 1 Positive Genetic
MRPS35 YGR165W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) physical 1 1 1 Affinity Capture-MS
ERV29 YGR284C Protein localized to COPII-coated vesicles genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex physical 1 1 1 Affinity Capture-MS
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 1 1 1 Negative Genetic
VAB2 YEL005C Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 PCA
ETT1 YOR051C Nuclear protein that inhibits replication of Brome mosaic virus physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Positive Genetic
RPL11A YPR102C Ribosomal 60S subunit protein L11A physical 1 1 1 Affinity Capture-MS
RPL11B YGR085C Ribosomal 60S subunit protein L11B physical 1 1 1 Affinity Capture-MS
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
PXL1 YKR090W Protein that localizes to sites of polarized growth physical 1 1 1 Affinity Capture-MS
CBP1 YJL209W Mitochondrial protein, regulator of COB mRNA stability and translation physical 1 1 1 Affinity Capture-MS
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response genetic 1 1 1 Positive Genetic
SYP1 YCR030C Negative regulator of WASP-Arp23 complex physical 1 1 1 Affinity Capture-MS
TUB1 YML085C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
NOP8 YOL144W Nucleolar protein required for 60S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
RPL28 YGL103W Ribosomal 60S subunit protein L28 physical 1 1 1 Affinity Capture-MS
RPL28 YGL103W Ribosomal 60S subunit protein L28 genetic 1 1 1 Negative Genetic
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
RPL18A YOL120C Ribosomal 60S subunit protein L18A physical 1 1 1 Affinity Capture-MS
RPL18B YNL301C Ribosomal 60S subunit protein L18B physical 1 1 1 Affinity Capture-MS
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS23B YPR132W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
GDH3 YAL062W NADP(+)-dependent glutamate dehydrogenase physical 1 1 1 Affinity Capture-MS
RRS1 YOR294W Essential protein that binds ribosomal protein L11 physical 1 1 1 Affinity Capture-MS
RPL14B YHL001W Ribosomal 60S subunit protein L14B physical 1 1 1 Affinity Capture-MS
TAO3 YIL129C Component of the RAM signaling network physical 1 1 1 Affinity Capture-MS
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Positive Genetic
RPL15A YLR029C Ribosomal 60S subunit protein L15A physical 1 1 1 Affinity Capture-MS
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
RPL19B YBL027W Ribosomal 60S subunit protein L19B physical 1 1 1 Affinity Capture-MS
RPL21A YBR191W Ribosomal 60S subunit protein L21A physical 1 1 1 Affinity Capture-MS
RPL21A YBR191W Ribosomal 60S subunit protein L21A genetic 1 1 1 Negative Genetic
RPL27B YDR471W Ribosomal 60S subunit protein L27B physical 1 1 1 Affinity Capture-MS
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 physical 1 1 1 Affinity Capture-MS
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs physical 1 1 1 Affinity Capture-MS
SBE22 YHR103W Protein involved in bud growth physical 1 1 1 Affinity Capture-MS
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Negative Genetic
ARO8 YGL202W Aromatic aminotransferase I physical 1 1 1 Affinity Capture-MS
ARO8 YGL202W Aromatic aminotransferase I genetic 1 1 1 Negative Genetic
MDM1 YML104C PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs physical 1 1 1 Affinity Capture-MS
MRC1 YCL061C S-phase checkpoint protein required for DNA replication physical 1 1 1 Affinity Capture-MS
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
TPM2 YIL138C Minor isoform of tropomyosin genetic 1 1 1 Negative Genetic
EPO1 YMR124W Protein involved in septin-ER tethering physical 1 1 1 Affinity Capture-MS
GTA1 YEL043W Protein of unknown function physical 1 1 1 Affinity Capture-MS
FUR1 YHR128W Uracil phosphoribosyltransferase genetic 1 1 1 Negative Genetic
PTR3 YFR029W Component of the SPS plasma membrane amino acid sensor system genetic 1 1 1 Negative Genetic
RPL16B YNL069C Ribosomal 60S subunit protein L16B physical 1 1 1 Affinity Capture-MS
RPL16B YNL069C Ribosomal 60S subunit protein L16B genetic 1 1 1 Negative Genetic
GPB1 YOR371C Multistep regulator of cAMP-PKA signaling physical 1 1 1 Affinity Capture-MS
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) physical 1 1 1 Affinity Capture-MS
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
RPL36B YPL249C-A Ribosomal 60S subunit protein L36B physical 1 1 1 Affinity Capture-MS
CIT1 YNR001C Mitochondrial citrate synthase physical 1 1 1 Affinity Capture-MS
CBS2 YDR197W Mitochondrial translational activator of the COB mRNA physical 1 1 1 Affinity Capture-MS
HSP31 YDR533C Methylglyoxalase that converts methylglyoxal to D-lactate genetic 1 1 1 Positive Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
FRK1 YPL141C Protein kinase of unknown cellular role physical 1 1 1 Affinity Capture-MS
HLR1 YDR528W Protein involved in regulation of cell wall composition and integrity physical 1 1 1 Affinity Capture-MS
HLR1 YDR528W Protein involved in regulation of cell wall composition and integrity genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p physical 1 1 1 Affinity Capture-MS
DUS3 YLR401C Dihydrouridine synthase physical 1 1 1 Affinity Capture-MS
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
SIA1 YOR137C Protein of unassigned function genetic 1 1 1 Negative Genetic
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Dosage Lethality
CST26 YBR042C Acyltransferase genetic 1 1 1 Negative Genetic
GTB1 YDR221W Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p genetic 1 1 1 Negative Genetic
TIM21 YGR033C Nonessential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
ANT1 YPR128C Peroxisomal adenine nucleotide transporter genetic 1 1 1 Negative Genetic
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Positive Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
MSS11 YMR164C Transcription factor physical 1 1 1 Affinity Capture-MS
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
RPS31 YLR167W Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin physical 1 1 1 Affinity Capture-MS
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p physical 1 1 1 Affinity Capture-MS
PEX1 YKL197C AAA-peroxin physical 1 1 1 Affinity Capture-MS
EXP1 YDL121C A cargo receptor protein for Pma1p physical 1 1 1 Affinity Capture-MS
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) genetic 1 1 1 Negative Genetic
OCH1 YGL038C Mannosyltransferase of the cis-Golgi apparatus physical 1 1 1 Affinity Capture-MS
NTH2 YBR001C Putative neutral trehalase, required for thermotolerance physical 1 1 1 Affinity Capture-MS
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B physical 1 1 1 Affinity Capture-MS
PBP4 YDL053C Pbp1p binding protein physical 1 1 1 Affinity Capture-MS
SRP14 YDL092W Signal recognition particle (SRP) subunit physical 1 1 1 Affinity Capture-MS
SOK1 YDR006C Protein of unknown function physical 1 1 1 Affinity Capture-MS
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
FCF2 YLR051C Nucleolar protein involved in the early steps of 35S rRNA processing physical 1 1 1 Affinity Capture-MS
FCF2 YLR051C Nucleolar protein involved in the early steps of 35S rRNA processing genetic 1 1 1 Negative Genetic
NAT5 YOR253W Subunit of protein N-terminal acetyltransferase NatA physical 1 1 1 Affinity Capture-MS
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Positive Genetic
GID11 YLR149C Substrate receptor of the glucose-induced degradation-deficient (GID) genetic 1 1 1 Negative Genetic
STP1 YDR463W Transcription factor genetic 1 1 1 Negative Genetic
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-MS
KXD1 YGL079W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 PCA
BLS1 YLR408C Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 PCA
SNN1 YNL086W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 PCA
GUK1 YDR454C Guanylate kinase genetic 1 1 1 Negative Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes physical 1 1 1 Affinity Capture-MS
MTG1 YMR097C Putative GTPase peripheral to the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
TOD6 YBL054W PAC motif binding protein involved in rRNA and ribosome biogenesis physical 1 1 1 Affinity Capture-MS
UBP2 YOR124C Ubiquitin-specific protease physical 1 1 1 Affinity Capture-MS
UBP2 YOR124C Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
CUE3 YGL110C Subunit of ribosome-associated quality control trigger complex (RQT) physical 1 1 1 Affinity Capture-MS
LCB5 YLR260W Minor sphingoid long-chain base kinase physical 1 1 1 Affinity Capture-MS
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis physical 1 1 1 Affinity Capture-MS
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
HOB2 YPR117W Protein with structural similarity to lipid transport protein Vps13p physical 1 1 1 Affinity Capture-MS
PPN1 YDR452W Dual endo- and exopolyphosphatase with a role in phosphate metabolism physical 1 1 1 Affinity Capture-MS
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Positive Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer physical 1 1 1 Affinity Capture-MS
RSM24 YDR175C Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
RSM24 YDR175C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
SSH1 YBR283C Subunit of the Ssh1 translocon complex physical 1 1 1 Affinity Capture-MS
CGI121 YML036W Component of the EKC/KEOPS complex genetic 1 1 1 Negative Genetic
SPC1 YJR010C-A Subunit of the signal peptidase complex (SPC) genetic 1 1 1 Negative Genetic
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 1 1 1 Negative Genetic
URB2 YJR041C Protein required for normal metabolism of the rRNA primary transcript genetic 1 1 1 Negative Genetic
THP3 YPR045C Protein that may have a role in transcription elongation physical 1 1 1 Affinity Capture-MS
LAM1 YHR155W Putative sterol transfer protein physical 1 1 1 Affinity Capture-MS
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
RDH54 YBR073W DNA-dependent ATPase physical 1 1 1 Affinity Capture-MS
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis physical 1 1 1 Affinity Capture-MS
VAC14 YLR386W Enzyme regulator physical 1 1 1 Affinity Capture-MS
MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
MRPL22 YNL177C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
ADE12 YNL220W Adenylosuccinate synthase physical 1 1 1 Affinity Capture-MS
GIP4 YAL031C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p physical 1 1 1 Affinity Capture-MS
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone physical 1 1 1 Affinity Capture-MS
TGL5 YOR081C Bifunctional triacylglycerol lipase and LPA acyltransferase physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
OXP1 YKL215C 5-oxoprolinase physical 1 1 1 Affinity Capture-MS
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Negative Genetic
AIM23 YJL131C Mitochondrial translation initiation factor 3 (IF3, mIF3) physical 1 1 1 Affinity Capture-MS
MRPL32 YCR003W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL12A YEL054C Ribosomal 60S subunit protein L12A physical 1 1 1 Affinity Capture-MS
COA3 YJL062W-A Mitochondrial protein required for cytochrome c oxidase assembly genetic 1 1 1 Negative Genetic
JJJ2 YJL162C Protein of unknown function physical 1 1 1 Affinity Capture-MS
TIR4 YOR009W Cell wall mannoprotein genetic 1 1 1 Negative Genetic
SRP68 YPL243W Core component of the signal recognition particle (SRP) complex physical 1 1 1 Affinity Capture-MS
GEP5 YLR091W Protein of unknown function physical 1 1 1 Affinity Capture-MS
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex physical 1 1 1 Affinity Capture-MS
TUB3 YML124C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
RPL24A YGL031C Ribosomal 60S subunit protein L24A physical 1 1 1 Affinity Capture-MS
RPL20A YMR242C Ribosomal 60S subunit protein L20A physical 1 1 1 Affinity Capture-MS
RPL20A YMR242C Ribosomal 60S subunit protein L20A genetic 1 1 1 Positive Genetic
TUB2 YFL037W Beta-tubulin physical 1 1 1 Affinity Capture-MS
RPS22B YLR367W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
ERP3 YDL018C Protein with similarity to Emp24p and Erv25p physical 1 1 1 Affinity Capture-MS
SDD3 YOL098C Putative metalloprotease physical 1 1 1 Affinity Capture-MS
RPL4B YDR012W Ribosomal 60S subunit protein L4B physical 1 1 1 Affinity Capture-MS
RPL13B YMR142C Ribosomal 60S subunit protein L13B physical 1 1 1 Affinity Capture-MS
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL7B YPL198W Ribosomal 60S subunit protein L7B physical 1 1 1 Affinity Capture-MS
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
RPL8B YLL045C Ribosomal 60S subunit protein L8A physical 1 1 1 Affinity Capture-MS
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase physical 1 1 1 Affinity Capture-MS
ATP25 YMR098C Protein that associates with mitochondrial ribosome physical 1 1 1 Affinity Capture-MS
RPL19A YBR084C-A Ribosomal 60S subunit protein L19A physical 1 1 1 Affinity Capture-MS
RPL35A YDL191W Ribosomal 60S subunit protein L35A physical 1 1 1 Affinity Capture-MS
RPL6B YLR448W Ribosomal 60S subunit protein L6B physical 1 1 1 Affinity Capture-MS
RPL6B YLR448W Ribosomal 60S subunit protein L6B genetic 1 1 1 Negative Genetic
RPL33B YOR234C Ribosomal 60S subunit protein L33B physical 1 1 1 Affinity Capture-MS
RPL43A YPR043W Ribosomal 60S subunit protein L43A physical 1 1 1 Affinity Capture-MS
RPL6A YML073C Ribosomal 60S subunit protein L6A physical 1 1 1 Affinity Capture-MS
UFD4 YKL010C Ubiquitin-protein ligase (E3) physical 1 1 1 Affinity Capture-MS
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
RSA3 YLR221C Protein with a likely role in ribosomal maturation physical 1 1 1 Affinity Capture-MS
SQS1 YNL224C Protein that stimulates the ATPase and helicase activities of Prp43p physical 1 1 1 Affinity Capture-MS
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes physical 1 1 1 Affinity Capture-MS
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 1 1 1 Negative Genetic
RPL35B YDL136W Ribosomal 60S subunit protein L35B physical 1 1 1 Affinity Capture-MS
RPL34A YER056C-A Ribosomal 60S subunit protein L34A physical 1 1 1 Affinity Capture-MS
RPL34B YIL052C Ribosomal 60S subunit protein L34B physical 1 1 1 Affinity Capture-MS
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
CAB1 YDR531W Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase genetic 1 1 1 Negative Genetic
KIN82 YCR091W Putative serine/threonine protein kinase genetic 1 1 1 Negative Genetic
DGA1 YOR245C Diacylglycerol acyltransferase physical 1 1 1 Affinity Capture-MS
PHO91 YNR013C Low-affinity vacuolar phosphate transporter physical 1 1 1 Affinity Capture-MS
ORM1 YGR038W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis physical 1 1 1 Affinity Capture-MS
PIK1 YNL267W Phosphatidylinositol 4-kinase genetic 1 1 1 Negative Genetic
RGD3 YHR182W GTPase activating protein (GAP) for Rho3p, involved in cell polarity g physical 1 1 1 Affinity Capture-MS
APS2 YJR058C Small subunit of the clathrin-associated adaptor complex AP-2 physical 1 1 1 Affinity Capture-MS
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein physical 1 1 1 Affinity Capture-MS
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Positive Genetic
LOA1 YPR139C Lysophosphatidic acid acyltransferase physical 1 1 1 Affinity Capture-MS
SYG1 YIL047C Plasma membrane protein of unknown function physical 1 1 1 Affinity Capture-MS
MPD1 YOR288C Member of the protein disulfide isomerase (PDI) family physical 1 1 1 Affinity Capture-MS
MTG2 YHR168W Putative GTPase physical 1 1 1 Affinity Capture-MS
DDP1 YOR163W Diadenosine and diphosphoinositol polyphosphate phosphatase genetic 1 1 1 Positive Genetic
AAD4 YDL243C Putative aryl-alcohol dehydrogenase genetic 1 1 1 Negative Genetic
TDA3 YHR009C Putative oxidoreductase involved in late endosome to Golgi transport physical 1 1 1 Affinity Capture-MS
TES1 YJR019C Peroxisomal acyl-CoA thioesterase physical 1 1 1 Affinity Capture-MS
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 1 1 1 Affinity Capture-MS
SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
PKP2 YGL059W Mitochondrial protein kinase physical 1 1 1 Affinity Capture-MS
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
RSM27 YGR215W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
RQT4 YKR023W Subunit of ribosome-associated quality control trigger complex (RQT) physical 1 1 1 Affinity Capture-MS
RPL14A YKL006W Ribosomal 60S subunit protein L14A physical 1 1 1 Affinity Capture-MS
ALG13 YGL047W Catalytic component of UDP-GlcNAc transferase genetic 1 1 1 Negative Genetic
RPL2B YIL018W Ribosomal 60S subunit protein L2B physical 1 1 1 Affinity Capture-MS
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
DCR2 YLR361C Protein phosphatase genetic 1 1 1 Negative Genetic
PEX3 YDR329C Peroxisomal membrane protein (PMP) physical 1 1 1 Affinity Capture-MS
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) physical 1 1 1 Affinity Capture-MS
ASI1 YMR119W Subunit of the inner nuclear membrane Asi ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
SPO14 YKR031C Phospholipase D physical 1 1 1 Affinity Capture-MS
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase physical 1 1 1 Affinity Capture-MS
CYC2 YOR037W Mitochondrial peripheral inner membrane protein physical 1 1 1 Affinity Capture-MS
PSR2 YLR019W Putative plasma membrane phosphatase physical 1 1 1 Affinity Capture-MS
CHS2 YBR038W Chitin synthase II physical 1 1 1 Affinity Capture-MS
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Negative Genetic
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Negative Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Positive Genetic
COQ4 YDR204W Protein with a role in ubiquinone (Coenzyme Q) biosynthesis physical 1 1 1 Affinity Capture-MS
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PTR2 YKR093W Integral membrane peptide transporter genetic 1 1 1 Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain physical 1 1 1 Affinity Capture-MS
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
EFG1 YGR271C-A Ribosome biogenesis factor required for maturation of 18S rRNA physical 1 1 1 Affinity Capture-MS
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
SSY1 YDR160W Component of the SPS plasma membrane amino acid sensor system genetic 1 1 1 Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Negative Genetic
PMC1 YGL006W Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions genetic 1 1 1 Dosage Rescue
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Negative Genetic
RTC1 YOL138C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Positive Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Positive Genetic
HLJ1 YMR161W Co-chaperone for Hsp40p physical 1 1 1 Affinity Capture-MS
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 1 1 1 Negative Genetic
MSC3 YLR219W Protein of unknown function physical 1 1 1 Affinity Capture-MS
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
EFR3 YMR212C Protein required for Stt4-containing PI kinase complex localization physical 1 1 1 Affinity Capture-MS
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Negative Genetic
ARO7 YPR060C Chorismate mutase genetic 1 1 1 Positive Genetic
BIG1 YHR101C Integral membrane protein of the endoplasmic reticulum genetic 1 1 1 Positive Genetic
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 1 1 1 Negative Genetic
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation physical 1 1 1 Affinity Capture-MS
FRT1 YOR324C Tail-anchored ER membrane protein of unknown function physical 1 1 1 Affinity Capture-MS
HPT1 YDR399W Dimeric hypoxanthine-guanine phosphoribosyltransferase genetic 1 1 1 Negative Genetic
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 1 1 1 Negative Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
MTC2 YKL098W Protein of unknown function physical 1 1 1 Affinity Capture-MS
HSP32 YPL280W Possible chaperone and cysteine protease genetic 1 1 1 Negative Genetic
ALK1 YGL021W Atypical protein kinase physical 1 1 1 Affinity Capture-MS
CRT10 YOL063C Protein required for the degradation of mutant 25S rRNAs physical 1 1 1 Affinity Capture-MS
RMD8 YFR048W Cytosolic protein required for sporulation physical 1 1 1 Affinity Capture-MS
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II physical 1 1 1 Affinity Capture-MS
IML2 YJL082W Protein required for clearance of inclusion bodies physical 1 1 1 Affinity Capture-MS
RHB1 YCR027C Putative Rheb-related GTPase physical 1 1 1 Affinity Capture-MS
PBI1 YPL272C Putative protein of unknown function genetic 1 1 1 Negative Genetic
LAM4 YHR080C Sterol-binding protein that localizes to puncta in the cortical ER physical 1 1 1 Affinity Capture-MS
SOV1 YMR066W Mitochondrial protein of unknown function physical 1 1 1 Affinity Capture-MS
GLO1 YML004C Monomeric glyoxalase I physical 1 1 1 Affinity Capture-MS
IFM1 YOL023W Mitochondrial translation initiation factor 2 physical 1 1 1 Affinity Capture-MS
RPO41 YFL036W Mitochondrial RNA polymerase physical 1 1 1 Affinity Capture-MS
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs physical 1 1 1 Affinity Capture-MS
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs physical 1 1 1 Affinity Capture-MS
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 1 1 1 Negative Genetic
HTS1 YPR033C Cytoplasmic and mitochondrial histidine tRNA synthetase physical 1 1 1 Affinity Capture-MS
RPL33A YPL143W Ribosomal 60S subunit protein L33A physical 1 1 1 Affinity Capture-MS
RPL33A YPL143W Ribosomal 60S subunit protein L33A genetic 1 1 1 Negative Genetic
RPL12B YDR418W Ribosomal 60S subunit protein L12B physical 1 1 1 Affinity Capture-MS
MAM3 YOL060C Protein involved in magnesium homeostasis physical 1 1 1 Affinity Capture-MS
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TGL3 YMR313C Bifunctional triacylglycerol lipase and LPE acyltransferase physical 1 1 1 Affinity Capture-MS
TDA5 YLR426W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
LDO45 YMR147W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
CMI7 YIL002W-A Putative mitochondrial protein of unknown function physical 1 1 1 Affinity Capture-MS
COX8 YLR395C Subunit VIII of cytochrome c oxidase (Complex IV) physical 1 1 1 Affinity Capture-MS
MRPL50 YNR022C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
MRPL31 YKL138C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MIC27 YNL100W Component of the MICOS complex genetic 1 1 1 Negative Genetic
GRX7 YBR014C Cis-golgi localized monothiol glutaredoxin genetic 1 1 1 Positive Genetic
LMO1 YLL007C Homolog of mammalian ELMO (Engulfment and celL MOtility) physical 1 1 1 Affinity Capture-MS
MCH4 YOL119C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Negative Genetic
AGC1 YPR021C Mitochondrial amino acid transporter physical 1 1 1 Affinity Capture-MS
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase physical 1 1 1 Affinity Capture-MS
MST1 YKL194C Mitochondrial threonyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
COS6 YGR295C Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
DLT1 YMR126C Protein of unknown function physical 1 1 1 Affinity Capture-MS
HXT14 YNL318C Protein with similarity to hexose transporter family members genetic 1 1 1 Negative Genetic
GUP2 YPL189W Probable membrane protein genetic 1 1 1 Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Negative Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein physical 1 1 1 Affinity Capture-MS
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SMY2 YBR172C GYF domain protein physical 1 1 1 Affinity Capture-MS
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder physical 1 1 1 Affinity Capture-MS
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex physical 1 1 1 Affinity Capture-MS
PEX35 YGR168C Regulator of peroxisome abundance genetic 1 1 1 Synthetic Growth Defect
NCA2 YPR155C Protein that regulates expression of Fo-F1 ATP synthase subunits physical 1 1 1 Affinity Capture-MS
ERJ5 YFR041C Type I membrane protein with a J domain physical 1 1 1 Affinity Capture-MS
ECM32 YER176W DNA dependent ATPase/DNA helicase physical 1 1 1 Affinity Capture-MS
CBT1 YKL208W Protein involved in 5' RNA end processing physical 1 1 1 Affinity Capture-MS
PET54 YGR222W Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
AIM36 YMR157C Protein of unknown function genetic 1 1 1 Negative Genetic
MTQ1 YNL063W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
SCP1 YOR367W Component of yeast cortical actin cytoskeleton physical 1 1 1 Affinity Capture-MS
PUT2 YHR037W Delta-1-pyrroline-5-carboxylate dehydrogenase physical 1 1 1 Affinity Capture-MS
DPI35 YMR130W Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
UTP30 YKR060W Subunit of U3-containing 90S preribosome complex physical 1 1 1 Affinity Capture-MS
UTP23 YOR004W Component of the small subunit processome physical 1 1 1 Affinity Capture-MS
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) physical 1 1 1 Affinity Capture-MS
SRP72 YPL210C Core component of the signal recognition particle (SRP) physical 1 1 1 Affinity Capture-MS
STB6 YKL072W Protein that binds Sin3p in a two-hybrid assay physical 1 1 1 Affinity Capture-MS
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP genetic 1 1 1 Negative Genetic
GYP8 YFL027C GTPase-activating protein for yeast Rab family members physical 1 1 1 Affinity Capture-MS
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
ECM14 YHR132C Conserved fungal protein with similarity to zinc carboxypeptidases genetic 1 1 1 Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Positive Genetic
MRX10 YDR282C Mitochondrial inner membrane protein of unknown function genetic 1 1 1 Negative Genetic
MRX8 YDR336W Protein that associates with mitochondrial ribosome physical 1 1 1 Affinity Capture-MS
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains physical 1 1 1 Affinity Capture-MS
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
SUL2 YLR092W High affinity sulfate permease genetic 1 1 1 Negative Genetic
UCC1 YLR224W F-box protein and component of SCF ubiquitin ligase complexes genetic 1 1 1 Positive Genetic
SMP1 YBR182C MADS-box transcription factor involved in osmotic stress response genetic 1 1 1 Negative Genetic
SEN34 YAR008W Subunit of the tRNA splicing endonuclease physical 1 1 1 Affinity Capture-MS
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) physical 1 1 1 Affinity Capture-MS
SLH1 YGR271W Subunit of ribosome-associated quality control trigger complex (RQT) physical 1 1 1 Affinity Capture-MS
MRX4 YPL168W Protein that associates with mitochondrial ribosome physical 1 1 1 Affinity Capture-MS
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway physical 1 1 1 Affinity Capture-MS
SAL1 YNL083W ADP/ATP transporter physical 1 1 1 Affinity Capture-MS
TGL4 YKR089C Multifunctional lipase/hydrolase/phospholipase physical 1 1 1 Affinity Capture-MS
TMA16 YOR252W Protein of unknown function that associates with ribosomes physical 1 1 1 Affinity Capture-MS
TOM7 YNL070W Component of the TOM (translocase of outer membrane) complex physical 1 1 1 Affinity Capture-MS
PET20 YPL159C Mitochondrial protein physical 1 1 1 Affinity Capture-MS
MTC4 YBR255W Protein of unknown function physical 1 1 1 Affinity Capture-MS
RTP1 YMR185W Protein required for the nuclear import and biogenesis of RNA pol II physical 1 1 1 Affinity Capture-MS
RSO55 YLR281C Mitochondrial protein of unknown function physical 1 1 1 Affinity Capture-MS
UBP16 YPL072W Deubiquitinating enzyme anchored to the outer mitochondrial membrane physical 1 1 1 Affinity Capture-MS
RSM26 YJR101W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
RMD9 YGL107C Mitochondrial protein that controls mitochondrial gene expression physical 1 1 1 Affinity Capture-MS
UBP1 YDL122W Ubiquitin-specific protease physical 1 1 1 Affinity Capture-MS
THR4 YCR053W Threonine synthase physical 1 1 1 Affinity Capture-MS
TSC10 YBR265W 3-ketosphinganine reductase genetic 1 1 1 Negative Genetic
BUD25 YER014C-A Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
RTS2 YOR077W Basic zinc-finger protein genetic 1 1 1 Negative Genetic
SOP4 YJL192C ER-membrane protein genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
SEC59 YMR013C Dolichol kinase genetic 1 1 1 Negative Genetic
ECM23 YPL021W Non-essential protein of unconfirmed function genetic 1 1 1 Positive Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
UTH1 YKR042W Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
UTR4 YEL038W Protein with sequence similarity to acireductone synthases genetic 1 1 1 Negative Genetic
SUT2 YPR009W Zn2Cys6 family transcription factor genetic 1 1 1 Negative Genetic
PGA1 YNL158W Essential component of GPI-mannosyltransferase II genetic 1 1 1 Negative Genetic
URA6 YKL024C Uridylate kinase genetic 1 1 1 Negative Genetic
TPN1 YGL186C Plasma membrane pyridoxine (vitamin B6) transporter genetic 1 1 1 Negative Genetic