Standard name Systematic name Name description Description
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family Cytoplasmic chaperone of the Hsp90 family; plays a role in determining prion variants; redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels than HSP82 and induced 2-3 fold by heat shock; contains two acid-rich unstructured regions that promote the solubility of chaperone-substrate complexes; HSC82 has a paralog, HSP82, that arose from the whole genome duplication
Visualize the interactome of HSC82
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.991 0.992 1.0

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 132000

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HSC82 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone physical 14 4 11 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Affinity Capture-MS
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity physical 9 6 7 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Reconstituted Complex, FRET, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 8 3 7 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 8 3 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones physical 7 5 7 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, FRET, Affinity Capture-MS, Co-crystal Structure
HSP82 YPL240C Hsp90 chaperone genetic 7 3 6 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic
SGT1 YOR057W Cochaperone protein physical 7 3 5 Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS
CDC37 YDR168W Essential Hsp90p co-chaperone physical 6 3 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 6 3 5 Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis physical 6 4 1 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 5 4 5 Protein-peptide, Co-crystal Structure, FRET, Reconstituted Complex, Reconstituted Complex
HSF1 YGL073W Trimeric heat shock transcription factor genetic 5 3 4 Dosage Rescue, Phenotypic Suppression, Dosage Rescue, Negative Genetic, Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 5 3 4 Negative Genetic, Dosage Rescue, Synthetic Lethality, Negative Genetic, Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 5 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 4 2 4 Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-RNA, Affinity Capture-MS
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone physical 4 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SGT1 YOR057W Cochaperone protein genetic 4 3 3 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 4 2 3 Negative Genetic, Phenotypic Suppression, Negative Genetic, Negative Genetic
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 4 3 2 Affinity Capture-MS, Co-purification, Reconstituted Complex, Affinity Capture-MS
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 3 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
SKP1 YDR328C Evolutionarily conserved kinetochore protein genetic 3 2 3 Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 3 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SSD1 YDR293C Translational repressor genetic 3 2 3 Synthetic Growth Defect, Positive Genetic, Positive Genetic
HCH1 YNL281W Heat shock protein regulator physical 3 2 3 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS
PPT1 YGR123C Protein serine/threonine phosphatase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SUP35 YDR172W Translation termination factor eRF3 physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
EPS1 YIL005W ER protein with chaperone and co-chaperone activity genetic 3 3 2 Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect
HGH1 YGR187C Chaperone protein for translation factor eEF2 genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
ABD1 YBR236C Methyltransferase genetic 3 2 2 Negative Genetic, Positive Genetic, Negative Genetic
UTP21 YLR409C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
DBP6 YNR038W Essential protein involved in ribosome biogenesis genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
CDC73 YLR418C Component of the Paf1p complex physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TPI1 YDR050C Triose phosphate isomerase, abundant glycolytic enzyme physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 2 2 2 DNA to cDNA expression microarray evidence, two-dimensional polyacrylamide gel electrophoresis evidence
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
HAS1 YMR290C ATP-dependent RNA helicase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CNS1 YBR155W TPR-containing co-chaperone physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
CNS1 YBR155W TPR-containing co-chaperone genetic 2 2 2 Dosage Rescue, Synthetic Growth Defect
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MSH2 YOL090W Protein that binds to DNA mismatches genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RAD51 YER095W Strand exchange protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
STE11 YLR362W Signal transducing MEK kinase physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
SSE2 YBR169C Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
MES1 YGR264C Methionyl-tRNA synthetase physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
UBP6 YFR010W Ubiquitin-specific protease genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 2 2 2 Synthetic Lethality, Negative Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
PMP3 YDR276C Small plasma membrane protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
TBF1 YPL128C Telobox-containing general regulatory factor genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
NOG1 YPL093W Putative GTPase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RPL36A YMR194W Ribosomal 60S subunit protein L36A genetic 2 2 2 Synthetic Growth Defect, Dosage Rescue
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
TTI2 YJR136C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 2 2 2 Negative Genetic, Dosage Lethality
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
ATP1 YBL099W Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
DST1 YGL043W General transcription elongation factor TFIIS genetic 2 1 2 Negative Genetic, Negative Genetic
APL2 YKL135C Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ARO1 YDR127W Pentafunctional arom protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SPT15 YER148W TATA-binding protein (TBP) genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
YPT6 YLR262C Rab family GTPase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TRP3 YKL211C Indole-3-glycerol-phosphate synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SAM1 YLR180W S-adenosylmethionine synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MIR1 YJR077C Mitochondrial phosphate carrier physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SKP1 YDR328C Evolutionarily conserved kinetochore protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MCA1 YOR197W Ca2+-dependent cysteine protease physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
OTU1 YFL044C Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
TUB1 YML085C Alpha-tubulin genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
YBR016W YBR016W Tail-anchored plasma membrane protein with a conserved CYSTM module genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RFS1 YBR052C Protein of unknown function genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MAL31 YBR298C Maltose permease genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RBK1 YCR036W Ribokinase, phosphorylates ribose to ribose-5-phosphate genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
TUP1 YCR084C General repressor of transcription in complex with Cyc8p genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RPL13A YDL082W Ribosomal 60S subunit protein L13A genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RPP1B YDL130W Ribosomal protein P1 beta genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RKM4 YDR257C Ribosomal lysine methyltransferase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RAD34 YDR314C Protein involved in nucleotide excision repair (NER) genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MSN5 YDR335W Karyopherin genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RPP2B YDR382W Ribosomal protein P2 beta genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
URH1 YDR400W Uridine nucleosidase (uridine-cytidine N-ribohydrolase) genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PAC2 YER007W Microtubule effector required for tubulin heterodimer formation genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MRF1 YGL143C Mitochondrial translation release factor genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RPL24B YGR148C Ribosomal 60S subunit protein L24B genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
LIN1 YHR156C Non-essential component of U5 snRNP genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RAM2 YKL019W Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PAN3 YKL025C Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SLD2 YKL108W Single-stranded DNA origin-binding and annealing protein genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
IRS4 YKR019C EH domain-containing protein genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PAU17 YLL025W Protein of unknown function genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RPL6A YML073C Ribosomal 60S subunit protein L6A genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MGL2 YMR210W Monoacylglycerol and triacylglycerol lipase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RPL20A YMR242C Ribosomal 60S subunit protein L20A genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SMM1 YNR015W Dihydrouridine synthase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MAM3 YOL060C Protein involved in magnesium homeostasis genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SFL1 YOR140W Transcriptional repressor and activator genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PDR5 YOR153W Plasma membrane ATP-binding cassette (ABC) transporter genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RPL33B YOR234C Ribosomal 60S subunit protein L33B genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MUM3 YOR298W Protein of unknown function involved in outer spore wall organization genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
YOR342C YOR342C Protein of unknown function genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
YPL068C YPL068C Protein of unknown function genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PRP28 YDR243C Pre-mRNA splicing factor genetic 2 1 2 Negative Genetic, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 2 1 2 Negative Genetic, Negative Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 2 1 2 Negative Genetic, Negative Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ACO1 YLR304C Aconitase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ATP3 YBR039W Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DUF1 YOL087C Ubiquitin-binding protein of unknown function genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
GCY1 YOR120W Glycerol dehydrogenase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ATC1 YDR184C Nuclear protein genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ATP12 YJL180C Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
COQ6 YGR255C Flavin-dependent monooxygenase involved in ubiquinone biosynthesis genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
EGH1 YIR007W Steryl-beta-glucosidase with broad specificity for aglycones genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
DIA1 YMR316W Protein of unknown function genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
GIS1 YDR096W Histone demethylase and transcription factor genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
FIT3 YOR383C Mannoprotein that is incorporated into the cell wall genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
HIS7 YBR248C Imidazole glycerol phosphate synthase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CCC2 YDR270W Cu(+2)-transporting P-type ATPase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
AGC1 YPR021C Mitochondrial amino acid transporter genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CAB2 YIL083C Phosphopantothenoylcysteine synthetase (PPCS) genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
EMC2 YJR088C Member of conserved ER transmembrane complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 2 2 1 Synthetic Growth Defect, Dosage Rescue
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 2 2 1 Synthetic Growth Defect, Dosage Growth Defect
TAH1 YCR060W Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) physical 2 2 1 Affinity Capture-MS, Reconstituted Complex
MYO1 YHR023W Type II myosin heavy chain physical 2 2 1 PCA, Affinity Capture-Western
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid genetic 2 2 1 Synthetic Growth Defect, Dosage Rescue
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 2 1 Phenotypic Suppression, Synthetic Growth Defect
RPN2 YIL075C Subunit of the 26S proteasome genetic 2 2 1 Synthetic Growth Defect, Dosage Rescue
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 2 2 1 Synthetic Growth Defect, Dosage Growth Defect
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 2 1 1 Negative Genetic, Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 2 1 1 Negative Genetic, Negative Genetic
AAR2 YBL074C Component of the U5 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
ARC40 YBR234C Subunit of the ARP2/3 complex genetic 2 1 1 Negative Genetic, Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 2 1 1 Negative Genetic, Negative Genetic
CYR1 YJL005W Adenylate cyclase genetic 2 1 1 Negative Genetic, Negative Genetic
FRS1 YLR060W Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase genetic 2 1 1 Negative Genetic, Negative Genetic
YAR009C YAR009C Retrotransposon TYA Gag and TYB Pol genes physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
PKC1 YBL105C Protein serine/threonine kinase genetic 2 1 1 Negative Genetic, Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 2 1 1 Negative Genetic, Negative Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
SKI6 YGR195W Exosome non-catalytic core component genetic 2 1 1 Negative Genetic, Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 2 1 1 Negative Genetic, Negative Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 2 1 1 Negative Genetic, Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 2 1 1 Negative Genetic, Negative Genetic
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase genetic 2 1 1 Negative Genetic, Negative Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 2 1 1 Negative Genetic, Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 2 1 1 Negative Genetic, Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 2 1 1 Negative Genetic, Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 2 1 1 PCA, PCA
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector physical 2 1 1 PCA, PCA
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 2 1 1 Negative Genetic, Negative Genetic
CDC123 YLR215C Assembly factor for the eIF2 translation initiation factor complex genetic 2 1 1 Negative Genetic, Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BAS1 YKR099W Myb-related transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT6 YGR116W Nucleosome remodeling protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis regulation 1 1 1 DNA to cDNA expression microarray evidence
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity regulation 1 1 1 quantitative western immunoblotting evidence
HCH1 YNL281W Heat shock protein regulator regulation 1 1 1 quantitative western immunoblotting evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Synthetic Growth Defect
CWC2 YDL209C Member of the NineTeen Complex (NTC) genetic 1 1 1 Synthetic Growth Defect
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Synthetic Growth Defect
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 1 1 1 Synthetic Growth Defect
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Growth Defect
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Growth Defect
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Negative Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
ADH1 YOL086C Alcohol dehydrogenase physical 1 1 1 Affinity Capture-MS
ADH1 YOL086C Alcohol dehydrogenase genetic 1 1 1 Synthetic Growth Defect
COR1 YBL045C Core subunit of the ubiquinol-cytochrome c reductase complex physical 1 1 1 Affinity Capture-MS
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Synthetic Growth Defect
ECM2 YBR065C Pre-mRNA splicing factor physical 1 1 1 Affinity Capture-MS
EMW1 YNL313C Essential conserved protein with a role in cell wall integrity genetic 1 1 1 Synthetic Growth Defect
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Synthetic Growth Defect
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function physical 1 1 1 Affinity Capture-MS
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic physical 1 1 1 Affinity Capture-MS
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Synthetic Growth Defect
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 Affinity Capture-MS
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Affinity Capture-MS
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Synthetic Growth Defect
FUN12 YAL035W Translation initiation factor eIF5B physical 1 1 1 Affinity Capture-MS
FUN12 YAL035W Translation initiation factor eIF5B genetic 1 1 1 Synthetic Growth Defect
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 1 1 1 Affinity Capture-MS
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Synthetic Growth Defect
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Affinity Capture-MS
CFT1 YDR301W RNA-binding subunit of the mRNA cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
GIR2 YDR152W Highly-acidic RWD domain-containing cytoplasmic protein physical 1 1 1 Affinity Capture-MS
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Phenotypic Suppression
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Growth Defect
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Synthetic Growth Defect
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 genetic 1 1 1 Synthetic Growth Defect
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme genetic 1 1 1 Negative Genetic
ADE13 YLR359W Adenylosuccinate lyase physical 1 1 1 Affinity Capture-MS
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) physical 1 1 1 Affinity Capture-MS
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) genetic 1 1 1 Synthetic Growth Defect
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 1 1 1 Synthetic Growth Defect
ARC19 YKL013C Subunit of the ARP2/3 complex genetic 1 1 1 Synthetic Growth Defect
ARC35 YNR035C Subunit of the ARP2/3 complex physical 1 1 1 Affinity Capture-MS
ARC40 YBR234C Subunit of the ARP2/3 complex physical 1 1 1 Affinity Capture-MS
ARP2 YDL029W Essential component of the Arp2/3 complex physical 1 1 1 Affinity Capture-MS
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Synthetic Lethality
ARP3 YJR065C Essential component of the Arp2/3 complex physical 1 1 1 Affinity Capture-MS
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Synthetic Growth Defect
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly genetic 1 1 1 Synthetic Growth Defect
CAP1 YKL007W Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) physical 1 1 1 Affinity Capture-MS
CAR1 YPL111W Arginase, catabolizes arginine to ornithine and urea physical 1 1 1 Affinity Capture-MS
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Synthetic Growth Defect
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
CDC10 YCR002C Component of the septin ring, required for cytokinesis physical 1 1 1 Affinity Capture-MS
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Affinity Capture-MS
ERG26 YGL001C C-3 sterol dehydrogenase physical 1 1 1 Affinity Capture-MS
BNI1 YNL271C Formin physical 1 1 1 Reconstituted Complex
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Synthetic Growth Defect
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
CHC1 YGL206C Clathrin heavy chain physical 1 1 1 Affinity Capture-MS
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
CYR1 YJL005W Adenylate cyclase physical 1 1 1 Affinity Capture-Western
CYS4 YGR155W Cystathionine beta-synthase physical 1 1 1 Affinity Capture-MS
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export physical 1 1 1 Affinity Capture-MS
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export genetic 1 1 1 Synthetic Growth Defect
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Synthetic Growth Defect
ENO1 YGR254W Enolase I, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase physical 1 1 1 Affinity Capture-MS
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
FRS1 YLR060W Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
GCN2 YDR283C Protein kinase genetic 1 1 1 Synthetic Growth Defect
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking physical 1 1 1 Affinity Capture-MS
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Synthetic Growth Defect
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
HAT2 YEL056W Subunit of the Hat1p-Hat2p histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Synthetic Growth Defect
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
COG8 YML071C Component of the conserved oligomeric Golgi complex physical 1 1 1 Affinity Capture-Western
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
ECM29 YHL030W Scaffold protein physical 1 1 1 Affinity Capture-MS
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family physical 1 1 1 Affinity Capture-MS
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase physical 1 1 1 Affinity Capture-MS
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase genetic 1 1 1 Synthetic Growth Defect
MRP4 YHL004W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
MSH2 YOL090W Protein that binds to DNA mismatches physical 1 1 1 Affinity Capture-MS
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Synthetic Growth Defect
PPT1 YGR123C Protein serine/threonine phosphatase genetic 1 1 1 Phenotypic Suppression
RAD51 YER095W Strand exchange protein physical 1 1 1 Affinity Capture-MS
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex physical 1 1 1 Two-hybrid
NPL6 YMR091C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
NPL6 YMR091C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
RSC3 YDR303C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
RSC8 YFR037C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
PRE1 YER012W Beta 4 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
KIC1 YHR102W Protein kinase of the PAK/Ste20 family, required for cell integrity physical 1 1 1 Affinity Capture-MS
NAF1 YNL124W RNA-binding protein required for the assembly of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex physical 1 1 1 Affinity Capture-MS
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Synthetic Growth Defect
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis physical 1 1 1 Affinity Capture-MS
SPT15 YER148W TATA-binding protein (TBP) physical 1 1 1 Affinity Capture-MS
RMD8 YFR048W Cytosolic protein required for sporulation physical 1 1 1 Affinity Capture-MS
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 1 1 1 Affinity Capture-MS
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Synthetic Growth Defect
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein physical 1 1 1 Affinity Capture-MS
PBA1 YLR199C Protein involved in 20S proteasome assembly physical 1 1 1 Affinity Capture-MS
YPT6 YLR262C Rab family GTPase physical 1 1 1 Affinity Capture-MS
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex physical 1 1 1 Affinity Capture-MS
UTP20 YBL004W Component of the small-subunit (SSU) processome physical 1 1 1 Affinity Capture-MS
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex physical 1 1 1 Affinity Capture-MS
STP4 YDL048C Protein containing a Kruppel-type zinc-finger domain physical 1 1 1 Affinity Capture-MS
STP4 YDL048C Protein containing a Kruppel-type zinc-finger domain genetic 1 1 1 Negative Genetic
TDH2 YJR009C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 physical 1 1 1 Affinity Capture-MS
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) physical 1 1 1 Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-MS
MRPL50 YNR022C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway physical 1 1 1 Affinity Capture-MS
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Affinity Capture-MS
NOP53 YPL146C Nucleolar protein physical 1 1 1 Affinity Capture-MS
STB3 YDR169C Ribosomal RNA processing element (RRPE)-binding protein physical 1 1 1 Affinity Capture-MS
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin genetic 1 1 1 Synthetic Growth Defect
SAM1 YLR180W S-adenosylmethionine synthetase genetic 1 1 1 Synthetic Growth Defect
NMD5 YJR132W Karyopherin physical 1 1 1 Affinity Capture-MS
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
YOL029C YOL029C Putative protein of unknown function physical 1 1 1 Two-hybrid
YOL029C YOL029C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SSA2 YLL024C HSP70 family ATP-binding protein genetic 1 1 1 Phenotypic Enhancement
TIF6 YPR016C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone genetic 1 1 1 Synthetic Growth Defect
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
HTZ1 YOL012C Histone variant H2AZ physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
IGO1 YNL157W Protein required for initiation of G0 program physical 1 1 1 Affinity Capture-MS
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Affinity Capture-Western
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Phenotypic Suppression
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Synthetic Growth Defect
LAS17 YOR181W Actin assembly factor physical 1 1 1 Affinity Capture-MS
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Growth Defect
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes physical 1 1 1 Affinity Capture-MS
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Synthetic Growth Defect
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex physical 1 1 1 Affinity Capture-MS
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Synthetic Growth Defect
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Synthetic Growth Defect
REV3 YPL167C Catalytic subunit of DNA polymerase zeta physical 1 1 1 Affinity Capture-MS
SNA4 YDL123W Protein of unknown function physical 1 1 1 Affinity Capture-MS
NDI1 YML120C NADH:ubiquinone oxidoreductase physical 1 1 1 Affinity Capture-MS
YIG1 YPL201C Protein that interacts with glycerol 3-phosphatase physical 1 1 1 Affinity Capture-MS
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis physical 1 1 1 Affinity Capture-MS
LSM1 YJL124C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 1 1 1 Synthetic Growth Defect
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 PCA
TFB4 YPR056W Subunit of TFIIH complex physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
OTU1 YFL044C Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p physical 1 1 1 Affinity Capture-MS
IRC20 YLR247C E3 ubiquitin ligase and putative helicase physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Synthetic Growth Defect
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Synthetic Growth Defect
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase genetic 1 1 1 Synthetic Growth Defect
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin genetic 1 1 1 Positive Genetic
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
PMP1 YCR024C-A Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p physical 1 1 1 Affinity Capture-RNA
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
TMA108 YIL137C Ribosome-associated, nascent chain binding factor genetic 1 1 1 Synthetic Growth Defect
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation physical 1 1 1 Affinity Capture-MS
VID24 YBR105C GID Complex regulatory subunit physical 1 1 1 Affinity Capture-MS
UTP21 YLR409C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 1 1 1 Affinity Capture-Western
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis genetic 1 1 1 Synthetic Growth Defect
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III genetic 1 1 1 Synthetic Growth Defect
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone physical 1 1 1 Affinity Capture-MS
HTS1 YPR033C Cytoplasmic and mitochondrial histidine tRNA synthetase physical 1 1 1 Affinity Capture-MS
HXK1 YFR053C Hexokinase isoenzyme 1 physical 1 1 1 Affinity Capture-MS
HXK2 YGL253W Hexokinase isoenzyme 2 physical 1 1 1 Affinity Capture-MS
HYR1 YIR037W Glutathione peroxidase physical 1 1 1 Affinity Capture-MS
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
ILV5 YLR355C Acetohydroxyacid reductoisomerase and mtDNA binding protein physical 1 1 1 Affinity Capture-MS
IML2 YJL082W Protein required for clearance of inclusion bodies physical 1 1 1 Affinity Capture-MS
IML2 YJL082W Protein required for clearance of inclusion bodies genetic 1 1 1 Synthetic Growth Defect
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) physical 1 1 1 Affinity Capture-MS
IRC24 YIR036C Putative benzil reductase physical 1 1 1 Affinity Capture-MS
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 physical 1 1 1 Affinity Capture-MS
KAP123 YER110C Karyopherin beta physical 1 1 1 Affinity Capture-MS
KAP95 YLR347C Karyopherin beta physical 1 1 1 Affinity Capture-MS
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Synthetic Growth Defect
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger physical 1 1 1 Affinity Capture-MS
KTR1 YOR099W Alpha-1,2-mannosyltransferase physical 1 1 1 Affinity Capture-MS
LEU2 YCL018W Beta-isopropylmalate dehydrogenase (IMDH) physical 1 1 1 Affinity Capture-MS
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) physical 1 1 1 Affinity Capture-MS
LYS12 YIL094C Homo-isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
LYS12 YIL094C Homo-isocitrate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
LYS21 YDL131W Homocitrate synthase isozyme physical 1 1 1 Affinity Capture-MS
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase physical 1 1 1 Affinity Capture-MS
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Synthetic Growth Defect
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Affinity Capture-MS
MET17 YLR303W O-acetyl homoserine-O-acetyl serine sulfhydrylase physical 1 1 1 Affinity Capture-MS
MET6 YER091C Cobalamin-independent methionine synthase physical 1 1 1 Affinity Capture-MS
MPD2 YOL088C Member of the protein disulfide isomerase (PDI) family physical 1 1 1 Affinity Capture-MS
MPM1 YJL066C Mitochondrial intermembrane space protein of unknown function physical 1 1 1 Affinity Capture-MS
MRI1 YPR118W 5'-methylthioribose-1-phosphate isomerase physical 1 1 1 Affinity Capture-MS
MRS6 YOR370C Rab escort protein physical 1 1 1 Affinity Capture-MS
MTD1 YKR080W NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase physical 1 1 1 Affinity Capture-MS
MTR4 YJL050W RNA duplex-sensing translocase physical 1 1 1 Affinity Capture-MS
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
NBP35 YGL091C Essential cytoplasmic iron-sulfur cluster binding protein physical 1 1 1 Affinity Capture-MS
NCP1 YHR042W NADP-cytochrome P450 reductase physical 1 1 1 Affinity Capture-MS
NDE1 YMR145C Mitochondrial external NADH dehydrogenase physical 1 1 1 Affinity Capture-MS
NEW1 YPL226W Translation termination and ribosome biogenesis factor physical 1 1 1 Affinity Capture-MS
NPA3 YJR072C Member of the conserved GPN-loop GTPase family physical 1 1 1 Affinity Capture-MS
NTH1 YDR001C Neutral trehalase, degrades trehalose physical 1 1 1 Affinity Capture-MS
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF physical 1 1 1 Affinity Capture-MS
OM45 YIL136W Mitochondrial outer membrane protein of unknown function physical 1 1 1 Affinity Capture-MS
OM45 YIL136W Mitochondrial outer membrane protein of unknown function genetic 1 1 1 Synthetic Growth Defect
PAA1 YDR071C Polyamine acetyltransferase physical 1 1 1 Affinity Capture-MS
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex physical 1 1 1 Affinity Capture-MS
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex physical 1 1 1 Affinity Capture-MS
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes physical 1 1 1 Affinity Capture-MS
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes genetic 1 1 1 Synthetic Growth Defect
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) physical 1 1 1 Affinity Capture-MS
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Synthetic Growth Defect
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane physical 1 1 1 Affinity Capture-MS
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase physical 1 1 1 Affinity Capture-MS
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 Affinity Capture-MS
PGM2 YMR105C Phosphoglucomutase physical 1 1 1 Affinity Capture-MS
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Affinity Capture-MS
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 Affinity Capture-MS
PIL1 YGR086C Eisosome core component physical 1 1 1 Affinity Capture-MS
PIM1 YBL022C ATP-dependent Lon protease physical 1 1 1 Affinity Capture-MS
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) physical 1 1 1 Affinity Capture-MS
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) physical 1 1 1 Affinity Capture-MS
PRM15 YMR278W Phosphoribomutase physical 1 1 1 Affinity Capture-MS
PRM15 YMR278W Phosphoribomutase genetic 1 1 1 Negative Genetic
PRO2 YOR323C Gamma-glutamyl phosphate reductase physical 1 1 1 Affinity Capture-MS
PRO3 YER023W Delta 1-pyrroline-5-carboxylate reductase physical 1 1 1 Affinity Capture-MS
PSA1 YDL055C GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) physical 1 1 1 Affinity Capture-MS
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex genetic 1 1 1 Synthetic Growth Defect
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
PYC2 YBR218C Pyruvate carboxylase isoform physical 1 1 1 Affinity Capture-MS
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) physical 1 1 1 Affinity Capture-MS
RBG2 YGR173W Protein with a role in translation physical 1 1 1 Affinity Capture-MS
RCN2 YOR220W Protein of unknown function physical 1 1 1 Affinity Capture-MS
RET2 YFR051C Delta subunit of the coatomer complex (COPI) physical 1 1 1 Affinity Capture-MS
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Synthetic Growth Defect
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) physical 1 1 1 Affinity Capture-MS
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p physical 1 1 1 Affinity Capture-MS
RNR2 YJL026W Ribonucleotide-diphosphate reductase (RNR), small subunit physical 1 1 1 Affinity Capture-MS
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit physical 1 1 1 Affinity Capture-MS
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Synthetic Growth Defect
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes physical 1 1 1 Affinity Capture-MS
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Synthetic Growth Defect
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RTN1 YDR233C Reticulon protein physical 1 1 1 Affinity Capture-MS
RTN2 YDL204W Reticulon protein physical 1 1 1 Affinity Capture-MS
RVS161 YCR009C Amphiphysin-like lipid raft protein physical 1 1 1 Affinity Capture-MS
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 1 1 1 Affinity Capture-MS
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase physical 1 1 1 Affinity Capture-MS
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Synthetic Growth Defect
SAC6 YDR129C Fimbrin, actin-bundling protein physical 1 1 1 Affinity Capture-MS
SAH1 YER043C S-adenosyl-L-homocysteine hydrolase physical 1 1 1 Affinity Capture-MS
SAR1 YPL218W ARF family GTPase physical 1 1 1 Affinity Capture-MS
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism physical 1 1 1 Affinity Capture-MS
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Synthetic Growth Defect
SDS24 YBR214W Protein involved in cell separation during budding physical 1 1 1 Affinity Capture-MS
SEC13 YLR208W Structural component of 3 complexes physical 1 1 1 Affinity Capture-MS
SEC17 YBL050W Alpha-SNAP cochaperone physical 1 1 1 Affinity Capture-MS
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone physical 1 1 1 Affinity Capture-MS
SEC21 YNL287W Gamma subunit of coatomer physical 1 1 1 Affinity Capture-MS
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 1 1 1 Affinity Capture-MS
SEC28 YIL076W Epsilon-COP subunit of the coatomer physical 1 1 1 Affinity Capture-MS
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Synthetic Growth Defect
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
SEC4 YFL005W Rab family GTPase physical 1 1 1 Affinity Capture-MS
SEC4 YFL005W Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
SEC53 YFL045C Phosphomannomutase physical 1 1 1 Affinity Capture-MS
SER1 YOR184W 3-phosphoserine aminotransferase physical 1 1 1 Affinity Capture-MS
SES1 YDR023W Cytosolic seryl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p genetic 1 1 1 Synthetic Growth Defect
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking physical 1 1 1 Affinity Capture-MS
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Synthetic Growth Defect
SSA4 YER103W Heat shock protein that is highly induced upon stress physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Synthetic Growth Defect
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 1 1 1 Affinity Capture-MS
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export physical 1 1 1 Affinity Capture-MS
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination physical 1 1 1 Affinity Capture-MS
SXM1 YDR395W Nuclear transport factor (karyopherin) physical 1 1 1 Affinity Capture-MS
TAL1 YLR354C Transaldolase, enzyme in the non-oxidative pentose phosphate pathway physical 1 1 1 Affinity Capture-MS
TDH1 YJL052W Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 physical 1 1 1 Affinity Capture-MS
TDH1 YJL052W Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 genetic 1 1 1 Synthetic Growth Defect
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Affinity Capture-MS
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
THS1 YIL078W Threonyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
THS1 YIL078W Threonyl-tRNA synthetase genetic 1 1 1 Negative Genetic
TIF1 YKR059W Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
TKL1 YPR074C Transketolase physical 1 1 1 Affinity Capture-MS
TMA19 YKL056C Protein that associates with ribosomes physical 1 1 1 Affinity Capture-MS
TMA19 YKL056C Protein that associates with ribosomes genetic 1 1 1 Synthetic Growth Defect
TOM40 YMR203W Component of the TOM (translocase of outer membrane) complex physical 1 1 1 Affinity Capture-MS
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex physical 1 1 1 Affinity Capture-MS
TRP2 YER090W Anthranilate synthase physical 1 1 1 Affinity Capture-MS
TRP5 YGL026C Tryptophan synthase physical 1 1 1 Affinity Capture-MS
TRX1 YLR043C Cytoplasmic thioredoxin isoenzyme physical 1 1 1 Affinity Capture-MS
TSA1 YML028W Thioredoxin peroxidase physical 1 1 1 Affinity Capture-MS
TSA2 YDR453C Stress inducible cytoplasmic thioredoxin peroxidase physical 1 1 1 Affinity Capture-MS
TUB2 YFL037W Beta-tubulin physical 1 1 1 Affinity Capture-MS
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Synthetic Growth Defect
TUF1 YOR187W Mitochondrial translation elongation factor Tu (EF-Tu) physical 1 1 1 Affinity Capture-MS
UBA1 YKL210W Ubiquitin activating enzyme (E1) physical 1 1 1 Affinity Capture-MS
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Affinity Capture-MS
UBP6 YFR010W Ubiquitin-specific protease physical 1 1 1 Affinity Capture-MS
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) physical 1 1 1 Affinity Capture-MS
URA7 YBL039C Major CTP synthase isozyme (see also URA8) physical 1 1 1 Affinity Capture-MS
VAC8 YEL013W Vacuole-specific Myo2p receptor physical 1 1 1 Affinity Capture-MS
VAS1 YGR094W Mitochondrial and cytoplasmic valyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 1 1 1 Affinity Capture-MS
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting physical 1 1 1 Affinity Capture-MS
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Synthetic Growth Defect
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting physical 1 1 1 Affinity Capture-MS
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Synthetic Growth Defect
WTM1 YOR230W Transcriptional modulator physical 1 1 1 Affinity Capture-MS
YBR053C YBR053C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YDR341C YDR341C Arginyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
YDR391C YDR391C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YET1 YKL065C Endoplasmic reticulum transmembrane protein physical 1 1 1 Affinity Capture-MS
YHB1 YGR234W Nitric oxide oxidoreductase physical 1 1 1 Affinity Capture-MS
YHR020W YHR020W Prolyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
YHR020W YHR020W Prolyl-tRNA synthetase genetic 1 1 1 Negative Genetic
NRE1 YIR035C Putative cytoplasmic short-chain dehydrogenase/reductase physical 1 1 1 Affinity Capture-MS
YJR096W YJR096W Xylose and arabinose reductase physical 1 1 1 Affinity Capture-MS
YJU3 YKL094W Monoglyceride lipase (MGL) that hydrolyzes fatty acid ethyl esters physical 1 1 1 Affinity Capture-MS
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling physical 1 1 1 Affinity Capture-MS
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
YKR018C YKR018C Protein of unknown function physical 1 1 1 Affinity Capture-MS
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity physical 1 1 1 Affinity Capture-MS
YMR226C YMR226C NADP(+)-dependent serine dehydrogenase and carbonyl reductase physical 1 1 1 Affinity Capture-MS
PYP1 YNL010W Sugar alcohol phosphatase physical 1 1 1 Affinity Capture-MS
SDD3 YOL098C Putative metalloprotease physical 1 1 1 Affinity Capture-MS
YOP1 YPR028W Reticulon-interacting protein physical 1 1 1 Affinity Capture-MS
YOR131C YOR131C Putative haloacid dehalogenase-like hydrolase physical 1 1 1 Affinity Capture-MS
YPK1 YKL126W S/T protein kinase physical 1 1 1 Affinity Capture-MS
YPK1 YKL126W S/T protein kinase genetic 1 1 1 Synthetic Growth Defect
YPL225W YPL225W Protein of unknown function physical 1 1 1 Affinity Capture-MS
YPL225W YPL225W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YPR127W YPR127W Putative pyridoxine 4-dehydrogenase physical 1 1 1 Affinity Capture-MS
YPT52 YKR014C Endosomal Rab family GTPase physical 1 1 1 Affinity Capture-MS
YRB1 YDR002W Ran GTPase binding protein physical 1 1 1 Affinity Capture-MS
YRB1 YDR002W Ran GTPase binding protein genetic 1 1 1 Synthetic Growth Defect
ZPR1 YGR211W Essential protein with two zinc fingers physical 1 1 1 Affinity Capture-MS
ZPR1 YGR211W Essential protein with two zinc fingers genetic 1 1 1 Synthetic Growth Defect
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
HSP104 YLL026W Disaggregase genetic 1 1 1 Phenotypic Suppression
HSP12 YFL014W Plasma membrane protein involved in maintaining membrane organization physical 1 1 1 Affinity Capture-MS
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
NQM1 YGR043C Transaldolase of unknown function physical 1 1 1 Affinity Capture-MS
RPL23A YBL087C Ribosomal 60S subunit protein L23A physical 1 1 1 Affinity Capture-MS
RPL23B YER117W Ribosomal 60S subunit protein L23B physical 1 1 1 Affinity Capture-MS
RPL23B YER117W Ribosomal 60S subunit protein L23B genetic 1 1 1 Synthetic Growth Defect
HYP2 YEL034W Translation elongation factor eIF-5A physical 1 1 1 Affinity Capture-MS
IDP1 YDL066W Mitochondrial NADP-specific isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
IMD3 YLR432W Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
LTP1 YPR073C Protein phosphotyrosine phosphatase of unknown cellular role physical 1 1 1 Affinity Capture-MS
RNR1 YER070W Major isoform of large subunit of ribonucleotide-diphosphate reductase physical 1 1 1 Affinity Capture-MS
RPL11A YPR102C Ribosomal 60S subunit protein L11A physical 1 1 1 Affinity Capture-MS
RPL1A YPL220W Ribosomal 60S subunit protein L1A physical 1 1 1 Affinity Capture-MS
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 Affinity Capture-MS
RPL4A YBR031W Ribosomal 60S subunit protein L4A genetic 1 1 1 Synthetic Growth Defect
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 1 1 1 Affinity Capture-MS
RPL5 YPL131W Ribosomal 60S subunit protein L5 genetic 1 1 1 Synthetic Growth Defect
RPL9A YGL147C Ribosomal 60S subunit protein L9A physical 1 1 1 Affinity Capture-MS
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 1 1 1 Negative Genetic
RPN2 YIL075C Subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer physical 1 1 1 Affinity Capture-MS
SSP120 YLR250W Protein packaged into COPII vesicles for ER to Golgi trafficking physical 1 1 1 Affinity Capture-MS
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Synthetic Growth Defect
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
TPS3 YMR261C Regulatory subunit of trehalose-6-phosphate synthase/phosphatase physical 1 1 1 Affinity Capture-MS
TUB1 YML085C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
TUB3 YML124C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation physical 1 1 1 Affinity Capture-MS
URA8 YJR103W Minor CTP synthase isozyme (see also URA7) physical 1 1 1 Affinity Capture-MS
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 1 1 1 Affinity Capture-MS
MLS1 YNL117W Malate synthase, enzyme of the glyoxylate cycle physical 1 1 1 Affinity Capture-MS
PCK1 YKR097W Phosphoenolpyruvate carboxykinase physical 1 1 1 Affinity Capture-MS
SDS23 YGL056C Protein involved in cell separation during budding physical 1 1 1 Affinity Capture-MS
SOL4 YGR248W 6-phosphogluconolactonase physical 1 1 1 Affinity Capture-MS
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex physical 1 1 1 Affinity Capture-MS
IKI3 YLR384C Subunit of Elongator complex physical 1 1 1 Affinity Capture-MS
ILV2 YMR108W Acetolactate synthase physical 1 1 1 Affinity Capture-MS
ILV3 YJR016C Dihydroxyacid dehydratase physical 1 1 1 Affinity Capture-MS
ILV3 YJR016C Dihydroxyacid dehydratase genetic 1 1 1 Synthetic Growth Defect
ILV6 YCL009C Regulatory subunit of acetolactate synthase physical 1 1 1 Affinity Capture-MS
LEU1 YGL009C Isopropylmalate isomerase physical 1 1 1 Affinity Capture-MS
MBF1 YOR298C-A Transcriptional coactivator physical 1 1 1 Affinity Capture-MS
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase physical 1 1 1 Affinity Capture-MS
OYE2 YHR179W Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) physical 1 1 1 Affinity Capture-MS
PCM1 YEL058W Essential N-acetylglucosamine-phosphate mutase physical 1 1 1 Affinity Capture-MS
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
PTC3 YBL056W Type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
RPL30 YGL030W Ribosomal 60S subunit protein L30 physical 1 1 1 Affinity Capture-MS
RPN13 YLR421C Subunit of the 19S regulatory particle of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
RPN9 YDR427W Non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RQC2 YPL009C Component of the Ribosome Quality Control (RQC) complex physical 1 1 1 Affinity Capture-MS
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase physical 1 1 1 Affinity Capture-MS
SRV2 YNL138W CAP (cyclase-associated protein) physical 1 1 1 Affinity Capture-MS
THR4 YCR053W Threonine synthase physical 1 1 1 Affinity Capture-MS
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
TIF3 YPR163C Translation initiation factor eIF-4B physical 1 1 1 Affinity Capture-MS
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase genetic 1 1 1 Synthetic Growth Defect
VMA4 YOR332W Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) physical 1 1 1 Affinity Capture-MS
VMA4 YOR332W Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) genetic 1 1 1 Synthetic Growth Defect
YNL134C YNL134C NADH-dependent aldehyde reductase physical 1 1 1 Affinity Capture-MS
YPR148C YPR148C Protein of unknown function physical 1 1 1 Affinity Capture-MS
ZUO1 YGR285C Ribosome-associated chaperone physical 1 1 1 Affinity Capture-MS
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport physical 1 1 1 Affinity Capture-MS
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering physical 1 1 1 Affinity Capture-MS
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering genetic 1 1 1 Synthetic Growth Defect
NET1 YJL076W Core subunit of the RENT complex physical 1 1 1 Affinity Capture-MS
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Synthetic Growth Defect
NMA2 YGR010W Nicotinic acid mononucleotide adenylyltransferase physical 1 1 1 Affinity Capture-MS
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences physical 1 1 1 Affinity Capture-MS
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences genetic 1 1 1 Synthetic Growth Defect
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
PNC1 YGL037C Nicotinamidase that converts nicotinamide to nicotinic acid physical 1 1 1 Affinity Capture-MS
RGI1 YER067W Protein involved in energy metabolism under respiratory conditions physical 1 1 1 Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Affinity Capture-MS
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p physical 1 1 1 Affinity Capture-MS
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p genetic 1 1 1 Negative Genetic
SEG2 YKL105C Eisosome component physical 1 1 1 Affinity Capture-MS
SER3 YER081W 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase physical 1 1 1 Affinity Capture-MS
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase physical 1 1 1 Affinity Capture-MS
SPA2 YLL021W Component of the polarisome physical 1 1 1 Affinity Capture-MS
SPA2 YLL021W Component of the polarisome genetic 1 1 1 Synthetic Growth Defect
TDA3 YHR009C Putative oxidoreductase involved in late endosome to Golgi transport physical 1 1 1 Affinity Capture-MS
TIF5 YPR041W Translation initiation factor eIF5 physical 1 1 1 Affinity Capture-MS
UGA1 YGR019W Gamma-aminobutyrate (GABA) transaminase physical 1 1 1 Affinity Capture-MS
YPT1 YFL038C Rab family GTPase physical 1 1 1 Affinity Capture-MS
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-MS
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Synthetic Lethality
STN1 YDR082W Telomere end-binding and capping protein genetic 1 1 1 Dosage Rescue
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SYN8 YAL014C Endosomal SNARE related to mammalian syntaxin 8 genetic 1 1 1 Synthetic Growth Defect
LDS1 YAL018C Protein Involved in spore wall assembly genetic 1 1 1 Synthetic Growth Defect
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Synthetic Growth Defect
SNC1 YAL030W Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Synthetic Growth Defect
PRP45 YAL032C Protein required for pre-mRNA splicing genetic 1 1 1 Synthetic Growth Defect
POP5 YAL033W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Synthetic Growth Defect
RBG1 YAL036C Member of the DRG family of GTP-binding proteins genetic 1 1 1 Synthetic Growth Defect
SEO1 YAL067C Putative permease genetic 1 1 1 Synthetic Growth Defect
SWH1 YAR042W Protein similar to mammalian oxysterol-binding protein genetic 1 1 1 Synthetic Growth Defect
LDB7 YBL006C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Synthetic Growth Defect
PSY4 YBL046W Regulatory subunit of protein phosphatase PP4 genetic 1 1 1 Synthetic Growth Defect
MOH1 YBL049W Protein of unknown function, essential for stationary phase survival genetic 1 1 1 Synthetic Growth Defect
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Synthetic Growth Defect
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
POA1 YBR022W Phosphatase that is highly specific for ADP-ribose 1''-phosphate genetic 1 1 1 Synthetic Growth Defect
REG2 YBR050C Regulatory subunit of the Glc7p type-1 protein phosphatase genetic 1 1 1 Synthetic Growth Defect
TRM7 YBR061C 2'-O-ribose methyltransferase genetic 1 1 1 Synthetic Growth Defect
YBR062C YBR062C Protein of unknown function that interacts with Msb2p genetic 1 1 1 Synthetic Growth Defect
YBR071W YBR071W Protein of unknown function found in the cytoplasm and bud neck genetic 1 1 1 Synthetic Growth Defect
TOS1 YBR162C Covalently-bound cell wall protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 1 1 1 Synthetic Growth Defect
PRP5 YBR237W RNA helicase in the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
RRT2 YBR246W Methylesterase performing penultimate step of diphthamide biosynthesis genetic 1 1 1 Synthetic Growth Defect
SPO23 YBR250W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MTC4 YBR255W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YBR259W YBR259W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 1 1 1 Synthetic Growth Defect
SAF1 YBR280C F-Box protein involved in proteasome-dependent degradation of Aah1p genetic 1 1 1 Synthetic Growth Defect
YCL001W-A YCL001W-A Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YCL002C YCL002C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
LDB16 YCL005W Protein involved in lipid droplet (LD) assembly genetic 1 1 1 Synthetic Growth Defect
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Synthetic Growth Defect
SRO9 YCL037C Cytoplasmic RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
VAC17 YCL063W Phosphoprotein involved in vacuole inheritance genetic 1 1 1 Synthetic Growth Defect
NPP1 YCR026C Nucleotide pyrophosphatase/phosphodiesterase genetic 1 1 1 Synthetic Growth Defect
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Synthetic Growth Defect
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Synthetic Growth Defect
RPL35B YDL136W Ribosomal 60S subunit protein L35B genetic 1 1 1 Synthetic Growth Defect
PCL9 YDL179W Cyclin genetic 1 1 1 Synthetic Growth Defect
YDL199C YDL199C Putative transporter genetic 1 1 1 Synthetic Growth Defect
MRPL11 YDL202W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins genetic 1 1 1 Synthetic Growth Defect
YDL211C YDL211C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SHR3 YDL212W Endoplasmic reticulum packaging chaperone genetic 1 1 1 Synthetic Growth Defect
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis genetic 1 1 1 Synthetic Growth Defect
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Synthetic Growth Defect
WHI4 YDL224C Putative RNA binding protein genetic 1 1 1 Synthetic Growth Defect
RCR2 YDR003W Vacuolar ubiquitin ligase-substrate adaptor genetic 1 1 1 Synthetic Growth Defect
RAD61 YDR014W Subunit of a complex that inhibits sister chromatid cohesion genetic 1 1 1 Synthetic Growth Defect
NSI1 YDR026C RNA polymerase I termination factor genetic 1 1 1 Synthetic Growth Defect
YDR042C YDR042C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Synthetic Growth Defect
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Synthetic Growth Defect
TRM1 YDR120C tRNA methyltransferase genetic 1 1 1 Synthetic Growth Defect
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Synthetic Growth Defect
NVJ3 YDR179W-A Protein with a potential role in tethering ER and vacuoles genetic 1 1 1 Synthetic Growth Defect
MET32 YDR253C Zinc-finger DNA-binding transcription factor genetic 1 1 1 Synthetic Growth Defect
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 1 1 1 Synthetic Growth Defect
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway genetic 1 1 1 Synthetic Growth Defect
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Synthetic Growth Defect
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Synthetic Growth Defect
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p genetic 1 1 1 Synthetic Growth Defect
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Synthetic Growth Defect
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Synthetic Growth Defect
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Synthetic Growth Defect
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Synthetic Growth Defect
YDR415C YDR415C Putative aminopeptidase genetic 1 1 1 Synthetic Growth Defect
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Synthetic Growth Defect
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
YDR444W YDR444W Putative hydrolase acting on ester bonds genetic 1 1 1 Synthetic Growth Defect
STP1 YDR463W Transcription factor genetic 1 1 1 Synthetic Growth Defect
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
VPS60 YDR486C Protein involved in late endosome to vacuole transport genetic 1 1 1 Synthetic Growth Defect
PKH1 YDR490C Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Synthetic Growth Defect
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Synthetic Growth Defect
TCA17 YEL048C Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Synthetic Growth Defect
MAK10 YEL053C Non-catalytic subunit of the NatC N-terminal acetyltransferase genetic 1 1 1 Synthetic Growth Defect
RMD6 YEL072W Protein required for sporulation genetic 1 1 1 Synthetic Growth Defect
MNN1 YER001W Alpha-1,3-mannosyltransferase genetic 1 1 1 Synthetic Growth Defect
TIR1 YER011W Cell wall mannoprotein genetic 1 1 1 Synthetic Growth Defect
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Synthetic Growth Defect
YER034W YER034W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YER039C-A YER039C-A Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
VTC1 YER072W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Synthetic Growth Defect
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Synthetic Growth Defect
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Synthetic Growth Defect
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Synthetic Growth Defect
HXT10 YFL011W Hexose transporter genetic 1 1 1 Synthetic Growth Defect
SMX2 YFL017W-A Core Sm protein Sm G genetic 1 1 1 Synthetic Growth Defect
PAU5 YFL020C Member of the seripauperin multigene family genetic 1 1 1 Synthetic Growth Defect
RPL22B YFL034C-A Ribosomal 60S subunit protein L22A genetic 1 1 1 Synthetic Growth Defect
LAM5 YFL042C Putative sterol transfer protein genetic 1 1 1 Synthetic Growth Defect
YFL051C YFL051C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA genetic 1 1 1 Synthetic Growth Defect
YFR006W YFR006W Putative X-Pro aminopeptidase genetic 1 1 1 Synthetic Growth Defect
YFH7 YFR007W Putative kinase with similarity to the PRK/URK/PANK kinase subfamily genetic 1 1 1 Synthetic Growth Defect
MIC19 YFR011C Component of the MICOS complex genetic 1 1 1 Synthetic Growth Defect
IOC3 YFR013W Subunit of the Isw1a complex genetic 1 1 1 Synthetic Growth Defect
IGD1 YFR017C Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity genetic 1 1 1 Synthetic Growth Defect
YFR018C YFR018C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ROG3 YFR022W Alpha-arrestin involved in ubiquitin-dependent endocytosis genetic 1 1 1 Synthetic Growth Defect
PES4 YFR023W Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation genetic 1 1 1 Synthetic Growth Defect
IRC6 YFR043C Clathrin coat accessory factor genetic 1 1 1 Synthetic Growth Defect
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response genetic 1 1 1 Synthetic Growth Defect
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Synthetic Growth Defect
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Synthetic Growth Defect
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Synthetic Growth Defect
PAN2 YGL094C Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 1 1 1 Synthetic Growth Defect
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Synthetic Growth Defect
VPS73 YGL104C Mitochondrial protein genetic 1 1 1 Synthetic Growth Defect
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
SUA5 YGL169W Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Synthetic Growth Defect
MIG2 YGL209W Zinc finger transcriptional repressor genetic 1 1 1 Synthetic Growth Defect
YPT32 YGL210W Rab family GTPase involved in the exocytic pathway genetic 1 1 1 Synthetic Growth Defect
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Synthetic Growth Defect
OST5 YGL226C-A Zeta subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Synthetic Growth Defect
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Synthetic Growth Defect
MCO32 YGR053C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Synthetic Growth Defect
YGR122W YGR122W Protein that may be involved in pH regulation genetic 1 1 1 Synthetic Growth Defect
VSB1 YGR125W Vacuolar membrane protein required for uptake and storage of arginine genetic 1 1 1 Synthetic Growth Defect
YGR127W YGR127W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Synthetic Growth Defect
YGR130C YGR130C Component of the eisosome with unknown function genetic 1 1 1 Synthetic Growth Defect
THI4 YGR144W Thiazole synthase genetic 1 1 1 Synthetic Growth Defect
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) genetic 1 1 1 Synthetic Growth Defect
PCT1 YGR202C Cholinephosphate cytidylyltransferase genetic 1 1 1 Synthetic Growth Defect
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome genetic 1 1 1 Synthetic Growth Defect
MAL11 YGR289C High-affinity maltose transporter (alpha-glucoside transporter) genetic 1 1 1 Synthetic Growth Defect
YHL012W YHL012W Putative UTP glucose-1-phosphate uridylyltransferase genetic 1 1 1 Synthetic Growth Defect
YLF2 YHL014C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Synthetic Growth Defect
RIM4 YHL024W Putative RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Synthetic Growth Defect
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Synthetic Growth Defect
MUP3 YHL036W Low affinity methionine permease genetic 1 1 1 Synthetic Growth Defect
QCR10 YHR001W-A Subunit of the ubiqunol-cytochrome c oxidoreductase complex genetic 1 1 1 Synthetic Growth Defect
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Synthetic Growth Defect
STP2 YHR006W Transcription factor genetic 1 1 1 Synthetic Growth Defect
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Synthetic Growth Defect
THR1 YHR025W Homoserine kinase genetic 1 1 1 Synthetic Growth Defect
YHI9 YHR029C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
INM1 YHR046C Inositol monophosphatase genetic 1 1 1 Synthetic Growth Defect
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Synthetic Growth Defect
OSH3 YHR073W Member of an oxysterol-binding protein family genetic 1 1 1 Synthetic Growth Defect
PPE1 YHR075C Protein with carboxyl methyl esterase activity genetic 1 1 1 Synthetic Growth Defect
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Synthetic Growth Defect
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Synthetic Growth Defect
RTC3 YHR087W Protein of unknown function involved in RNA metabolism genetic 1 1 1 Synthetic Growth Defect
HXT4 YHR092C High-affinity glucose transporter genetic 1 1 1 Synthetic Growth Defect
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Synthetic Growth Defect
PEX28 YHR150W Peroxisomal integral membrane peroxin genetic 1 1 1 Synthetic Growth Defect
SPO12 YHR152W Nucleolar protein of unknown function genetic 1 1 1 Synthetic Growth Defect
KEL1 YHR158C Protein required for proper cell fusion and cell morphology genetic 1 1 1 Synthetic Growth Defect
PEX18 YHR160C Peroxin genetic 1 1 1 Synthetic Growth Defect
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Synthetic Growth Defect
MTG2 YHR168W Putative GTPase genetic 1 1 1 Synthetic Growth Defect
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 1 1 1 Synthetic Growth Defect
NVJ1 YHR195W Nuclear envelope protein genetic 1 1 1 Synthetic Growth Defect
YIL001W YIL001W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Synthetic Growth Defect
VID28 YIL017C GID Complex subunit, serves as adaptor for regulatory subunit Vid24p genetic 1 1 1 Synthetic Growth Defect
YKE4 YIL023C Zinc transporter genetic 1 1 1 Synthetic Growth Defect
SYG1 YIL047C Plasma membrane protein of unknown function genetic 1 1 1 Synthetic Growth Defect
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Synthetic Growth Defect
RPL34B YIL052C Ribosomal 60S subunit protein L34B genetic 1 1 1 Synthetic Growth Defect
RGI2 YIL057C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
RCI37 YIL077C Protein that associates with the large mitoribosomal subunit genetic 1 1 1 Synthetic Growth Defect
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p genetic 1 1 1 Synthetic Growth Defect
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Synthetic Growth Defect
QDR2 YIL121W Plasma membrane transporter of the major facilitator superfamily genetic 1 1 1 Synthetic Growth Defect
REV7 YIL139C Accessory subunit of DNA polymerase zeta genetic 1 1 1 Synthetic Growth Defect
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis genetic 1 1 1 Synthetic Growth Defect
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions genetic 1 1 1 Synthetic Growth Defect
SOA1 YIL166C Sulfonate and inorganic sulfur transporter genetic 1 1 1 Synthetic Growth Defect
SGN1 YIR001C Cytoplasmic RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) genetic 1 1 1 Synthetic Growth Defect
SYS1 YJL004C Integral membrane protein of the Golgi genetic 1 1 1 Synthetic Growth Defect
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Synthetic Growth Defect
LOH1 YJL038C Protein involved in outer spore wall assembly genetic 1 1 1 Synthetic Growth Defect
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Synthetic Growth Defect
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 1 1 1 Synthetic Growth Defect
JEM1 YJL073W DnaJ-like chaperone required for nuclear membrane fusion during mating genetic 1 1 1 Synthetic Growth Defect
YJL107C YJL107C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Synthetic Growth Defect
NIT2 YJL126W Nit protein genetic 1 1 1 Synthetic Growth Defect
MRS3 YJL133W Iron transporter, mediates Fe2+ transport across inner mito membrane genetic 1 1 1 Synthetic Growth Defect
LCB3 YJL134W Long-chain base-1-phosphate phosphatase genetic 1 1 1 Synthetic Growth Defect
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Synthetic Growth Defect
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Synthetic Growth Defect
TOH1 YJL171C GPI-anchored cell wall protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Synthetic Growth Defect
YJL193W YJL193W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Synthetic Growth Defect
TMA22 YJR014W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
RAD7 YJR052W Nucleotide excision repair (NER) protein genetic 1 1 1 Synthetic Growth Defect
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Synthetic Growth Defect
YJR056C YJR056C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Synthetic Growth Defect
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 1 1 1 Synthetic Growth Defect
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Synthetic Growth Defect
PXP2 YJR111C Peroxisomal matrix protein with naturally active promoter genetic 1 1 1 Synthetic Growth Defect
YJR142W YJR142W 8-oxo-dGTP diphosphatase of the Nudix hydrolase family genetic 1 1 1 Synthetic Growth Defect
YKL033W-A YKL033W-A Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Synthetic Growth Defect
SPC42 YKL042W Central plaque component of spindle pole body (SPB) genetic 1 1 1 Synthetic Growth Defect
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Synthetic Growth Defect
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 genetic 1 1 1 Synthetic Growth Defect
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
PEX1 YKL197C AAA-peroxin genetic 1 1 1 Synthetic Growth Defect
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Synthetic Growth Defect
MRS4 YKR052C Iron transporter of the mitochondrial carrier family genetic 1 1 1 Synthetic Growth Defect
KTR2 YKR061W Mannosyltransferase involved in N-linked protein glycosylation genetic 1 1 1 Synthetic Growth Defect
TFA2 YKR062W TFIIE small subunit genetic 1 1 1 Synthetic Growth Defect
PTR2 YKR093W Integral membrane peptide transporter genetic 1 1 1 Synthetic Growth Defect
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
SFI1 YLL003W Centrin (Cdc31p)-binding protein required for SPB duplication genetic 1 1 1 Synthetic Growth Defect
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Synthetic Growth Defect
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
YLL032C YLL032C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Synthetic Growth Defect
YLR012C YLR012C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p genetic 1 1 1 Synthetic Growth Defect
SNF7 YLR025W One of four subunits of the ESCRT-III complex genetic 1 1 1 Synthetic Growth Defect
YLR031W YLR031W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
PER33 YLR064W Protein that localizes to the endoplasmic reticulum genetic 1 1 1 Synthetic Growth Defect
XYL2 YLR070C Xylitol dehydrogenase genetic 1 1 1 Synthetic Growth Defect
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Synthetic Growth Defect
XDJ1 YLR090W Chaperone with a role in facilitating mitochondrial protein import genetic 1 1 1 Synthetic Growth Defect
ICT1 YLR099C Lysophosphatidic acid acyltransferase genetic 1 1 1 Synthetic Growth Defect
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Synthetic Growth Defect
USB1 YLR132C Putative poly(U)-specific 3'-to-5' RNA exonuclease genetic 1 1 1 Synthetic Growth Defect
PUS5 YLR165C Pseudouridine synthase genetic 1 1 1 Synthetic Growth Defect
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein genetic 1 1 1 Synthetic Growth Defect
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 1 1 1 Synthetic Growth Defect
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Synthetic Growth Defect
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Synthetic Growth Defect
NMA1 YLR328W Nicotinic acid mononucleotide adenylyltransferase genetic 1 1 1 Synthetic Growth Defect
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Synthetic Growth Defect
SPO77 YLR341W Meiosis-specific protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Synthetic Growth Defect
NMD4 YLR363C Protein that may be involved in nonsense-mediated mRNA decay genetic 1 1 1 Synthetic Growth Defect
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Synthetic Growth Defect
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Synthetic Growth Defect
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Synthetic Growth Defect
YLR407W YLR407W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
VPS36 YLR417W Component of the ESCRT-II complex genetic 1 1 1 Synthetic Growth Defect
YPT7 YML001W Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 1 1 1 Synthetic Growth Defect
NDC1 YML031W Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
YMD8 YML038C Putative nucleotide sugar transporter genetic 1 1 1 Synthetic Growth Defect
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Synthetic Growth Defect
YML079W YML079W Non-essential protein of unknown function genetic 1 1 1 Synthetic Growth Defect
NAB6 YML117W Putative RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay genetic 1 1 1 Synthetic Growth Defect
STV1 YMR054W Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Synthetic Growth Defect
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SOV1 YMR066W Mitochondrial protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Synthetic Growth Defect
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Synthetic Growth Defect
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein genetic 1 1 1 Synthetic Growth Defect
SNO1 YMR095C Protein of unconfirmed function genetic 1 1 1 Synthetic Growth Defect
YMR099C YMR099C Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) genetic 1 1 1 Synthetic Growth Defect
MGR3 YMR115W Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Synthetic Growth Defect
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Synthetic Growth Defect
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Synthetic Growth Defect
YMR206W YMR206W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SCJ1 YMR214W One of several homologs of bacterial chaperone DnaJ genetic 1 1 1 Synthetic Growth Defect
TRS130 YMR218C Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Synthetic Growth Defect
TAF7 YMR227C TFIID subunit (67 kDa) genetic 1 1 1 Synthetic Growth Defect
URA10 YMR271C Minor orotate phosphoribosyltransferase (OPRTase) isozyme genetic 1 1 1 Synthetic Growth Defect
RCE1 YMR274C Type II CAAX prenyl protease genetic 1 1 1 Synthetic Growth Defect
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Synthetic Growth Defect
PRC1 YMR297W Vacuolar carboxypeptidase Y (proteinase C, CPY) genetic 1 1 1 Synthetic Growth Defect
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination genetic 1 1 1 Synthetic Growth Defect
IDP3 YNL009W Peroxisomal NADP-dependent isocitrate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
PBI2 YNL015W Cytosolic inhibitor of vacuolar proteinase B (PRB1) genetic 1 1 1 Synthetic Growth Defect
RCM1 YNL022C rRNA m5C methyltransferase genetic 1 1 1 Synthetic Growth Defect
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Synthetic Growth Defect
YNL035C YNL035C Nuclear protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YNL058C YNL058C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Synthetic Growth Defect
YNL108C YNL108C Protein phosphatase genetic 1 1 1 Synthetic Growth Defect
WHI3 YNL197C RNA binding protein that modulates mRNA stability genetic 1 1 1 Synthetic Growth Defect
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Synthetic Growth Defect
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
LAP3 YNL239W Cysteine aminopeptidase with homocysteine-thiolactonase activity genetic 1 1 1 Synthetic Growth Defect
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Synthetic Growth Defect
PDR17 YNL264C Phosphatidylinositol transfer protein (PITP) genetic 1 1 1 Synthetic Growth Defect
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway genetic 1 1 1 Synthetic Growth Defect
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Synthetic Growth Defect
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 1 1 1 Synthetic Growth Defect
PFS2 YNL317W Integral subunit of the pre-mRNA CPF complex genetic 1 1 1 Synthetic Growth Defect
YNL320W YNL320W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Synthetic Growth Defect
YRF1-6 YNL339C Helicase encoded by the Y' element of subtelomeric regions genetic 1 1 1 Synthetic Growth Defect
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Synthetic Growth Defect
LRO1 YNR008W Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) genetic 1 1 1 Synthetic Growth Defect
URK1 YNR012W Uridine/cytidine kinase genetic 1 1 1 Synthetic Growth Defect
YNR014W YNR014W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YNR021W YNR021W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MRX15 YNR040W Membrane-associated mitoribosome receptor genetic 1 1 1 Synthetic Growth Defect
PET494 YNR045W Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Synthetic Growth Defect
MNT4 YNR059W Putative alpha-1,3-mannosyltransferase genetic 1 1 1 Synthetic Growth Defect
YNR071C YNR071C Putative aldose 1-epimerase genetic 1 1 1 Synthetic Growth Defect
PFA4 YOL003C Palmitoyltransferase with autoacylation activity genetic 1 1 1 Synthetic Growth Defect
YOL013W-A YOL013W-A Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
TAT2 YOL020W High affinity tryptophan and tyrosine permease genetic 1 1 1 Synthetic Growth Defect
YOL024W YOL024W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YOL036W YOL036W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
RPP2A YOL039W Ribosomal protein P2 alpha genetic 1 1 1 Synthetic Growth Defect
NGL1 YOL042W Putative endonuclease genetic 1 1 1 Synthetic Growth Defect
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase genetic 1 1 1 Synthetic Growth Defect
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body genetic 1 1 1 Synthetic Growth Defect
SHR5 YOL110W Palmitoyltransferase subunit genetic 1 1 1 Synthetic Growth Defect
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Synthetic Growth Defect
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 1 1 1 Synthetic Growth Defect
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases genetic 1 1 1 Synthetic Growth Defect
YOL131W YOL131W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Synthetic Growth Defect
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Synthetic Growth Defect
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Synthetic Growth Defect
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome genetic 1 1 1 Synthetic Growth Defect
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
TRS33 YOR115C Core component of TRAPP complexes I, II and IV genetic 1 1 1 Synthetic Growth Defect
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Synthetic Growth Defect
TRE2 YOR256C Transferrin receptor-like protein genetic 1 1 1 Synthetic Growth Defect
MOD5 YOR274W Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase genetic 1 1 1 Synthetic Growth Defect
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Synthetic Growth Defect
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Synthetic Growth Defect
SLY41 YOR307C Protein involved in ER-to-Golgi transport genetic 1 1 1 Synthetic Growth Defect
SFG1 YOR315W Nuclear protein putative transcription factor genetic 1 1 1 Synthetic Growth Defect
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Synthetic Growth Defect
SNX3 YOR357C Sorting nexin for late-Golgi enzymes genetic 1 1 1 Synthetic Growth Defect
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Synthetic Growth Defect
NUD1 YOR373W Mitotic exit network (MEN) scaffold protein genetic 1 1 1 Synthetic Growth Defect
SNF8 YPL002C Component of the ESCRT-II complex genetic 1 1 1 Synthetic Growth Defect
VPS28 YPL065W Component of the ESCRT-I complex genetic 1 1 1 Synthetic Growth Defect
YPL077C YPL077C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Synthetic Growth Defect
KAP120 YPL125W Karyopherin responsible for the nuclear import of Rpf1p genetic 1 1 1 Synthetic Growth Defect
PRM4 YPL156C Pheromone-regulated protein proposed to be involved in mating genetic 1 1 1 Synthetic Growth Defect
OYE3 YPL171C Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) genetic 1 1 1 Synthetic Growth Defect
SPT14 YPL175W UDP-glycosyltransferase subunit of the GPI-GnT complex genetic 1 1 1 Synthetic Growth Defect
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) genetic 1 1 1 Synthetic Growth Defect
MF(ALPHA)1 YPL187W Mating pheromone alpha-factor, made by alpha cells genetic 1 1 1 Synthetic Growth Defect
YPL199C YPL199C Protein involved in nonstop mRNA decay genetic 1 1 1 Synthetic Growth Defect
SRP68 YPL243W Core component of the signal recognition particle (SRP) complex genetic 1 1 1 Synthetic Growth Defect
HUT1 YPL244C Protein with a role in UDP-galactose transport to the Golgi lumen genetic 1 1 1 Synthetic Growth Defect
YPL257W YPL257W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
PLC1 YPL268W Phospholipase C genetic 1 1 1 Synthetic Growth Defect
KAR9 YPL269W Spindle positioning factor genetic 1 1 1 Synthetic Growth Defect
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Synthetic Growth Defect
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 1 1 1 Synthetic Growth Defect
MAK3 YPR051W Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) genetic 1 1 1 Synthetic Growth Defect
NVJ2 YPR091C Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) genetic 1 1 1 Synthetic Growth Defect
NOC4 YPR144C Nucleolar protein genetic 1 1 1 Synthetic Growth Defect
YPR147C YPR147C Bifunctional triacylglycerol lipase and short chain ester hydrolase genetic 1 1 1 Synthetic Growth Defect
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins genetic 1 1 1 Synthetic Growth Defect
PDS1 YDR113C Securin genetic 1 1 1 Synthetic Growth Defect
HTA1 YDR225W Histone H2A genetic 1 1 1 Negative Genetic
HTB1 YDR224C Histone H2B genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Synthetic Rescue
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Positive Genetic
HSL7 YBR133C Protein arginine N-methyltransferase genetic 1 1 1 Synthetic Growth Defect
HTL1 YCR020W-B Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
HXT3 YDR345C Low affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Synthetic Growth Defect
IAH1 YOR126C Isoamyl acetate-hydrolyzing esterase genetic 1 1 1 Synthetic Growth Defect
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Synthetic Growth Defect
JLP1 YLL057C Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase genetic 1 1 1 Synthetic Growth Defect
KGD1 YIL125W Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex genetic 1 1 1 Synthetic Growth Defect
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Synthetic Growth Defect
LCB5 YLR260W Minor sphingoid long-chain base kinase genetic 1 1 1 Synthetic Growth Defect
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Synthetic Growth Defect
MAP1 YLR244C Methionine aminopeptidase genetic 1 1 1 Synthetic Growth Defect
MAS2 YHR024C Alpha subunit of the mitochondrial processing protease (MPP) genetic 1 1 1 Synthetic Growth Defect
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Synthetic Growth Defect
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Synthetic Growth Defect
MSS2 YDL107W Peripherally bound inner membrane protein of the mitochondrial matrix genetic 1 1 1 Synthetic Growth Defect
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Synthetic Growth Defect
NCR1 YPL006W Vacuolar membrane protein involved with Npc2p in sterol trafficking genetic 1 1 1 Synthetic Growth Defect
NDD1 YOR372C Transcriptional activator essential for nuclear division genetic 1 1 1 Synthetic Growth Defect
NEJ1 YLR265C DNA end-binding protein required for nonhomologous end joining (NHEJ) genetic 1 1 1 Synthetic Growth Defect
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes genetic 1 1 1 Synthetic Growth Defect
NOP15 YNL110C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Synthetic Growth Defect
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Synthetic Growth Defect
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Synthetic Growth Defect
NUP1 YOR098C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Synthetic Growth Defect
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 1 1 1 Synthetic Growth Defect
PCS60 YBR222C Oxalyl-CoA synthetase genetic 1 1 1 Synthetic Growth Defect
PDR16 YNL231C Phosphatidylinositol transfer protein (PITP) genetic 1 1 1 Synthetic Growth Defect
PER1 YCR044C Protein of the endoplasmic reticulum genetic 1 1 1 Synthetic Growth Defect
PET100 YDR079W Chaperone that facilitates the assembly of cytochrome c oxidase genetic 1 1 1 Synthetic Growth Defect
PHM6 YDR281C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Synthetic Growth Defect
PRM5 YIL117C Pheromone-regulated protein, predicted to have 1 transmembrane segment genetic 1 1 1 Synthetic Growth Defect
PRM8 YGL053W Pheromone-regulated protein genetic 1 1 1 Synthetic Growth Defect
PRO1 YDR300C Gamma-glutamyl kinase genetic 1 1 1 Synthetic Growth Defect
PRY3 YJL078C GPI-anchored cell wall protein involved in export of sterols genetic 1 1 1 Synthetic Growth Defect
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Synthetic Growth Defect
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress genetic 1 1 1 Synthetic Growth Defect
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Synthetic Growth Defect
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p genetic 1 1 1 Synthetic Growth Defect
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Synthetic Growth Defect
RNH202 YDR279W Ribonuclease H2 subunit genetic 1 1 1 Synthetic Growth Defect
ROG1 YGL144C Lipase with specificity for monoacylglycerol genetic 1 1 1 Synthetic Growth Defect
RPC19 YNL113W RNA polymerase subunit AC19 genetic 1 1 1 Synthetic Growth Defect
RPL13B YMR142C Ribosomal 60S subunit protein L13B genetic 1 1 1 Synthetic Growth Defect
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Synthetic Growth Defect
RPL17A YKL180W Ribosomal 60S subunit protein L17A genetic 1 1 1 Synthetic Growth Defect
RPL19B YBL027W Ribosomal 60S subunit protein L19B genetic 1 1 1 Synthetic Growth Defect
RPL21A YBR191W Ribosomal 60S subunit protein L21A genetic 1 1 1 Synthetic Growth Defect
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Synthetic Growth Defect
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 1 1 1 Synthetic Growth Defect
RPL28 YGL103W Ribosomal 60S subunit protein L28 genetic 1 1 1 Synthetic Growth Defect
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Synthetic Growth Defect
RPS17B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit genetic 1 1 1 Synthetic Growth Defect
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Synthetic Growth Defect
RRP9 YPR137W Protein involved in pre-rRNA processing genetic 1 1 1 Synthetic Growth Defect
SCW11 YGL028C Cell wall protein with similarity to glucanases genetic 1 1 1 Synthetic Growth Defect
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Synthetic Growth Defect
SIP1 YDR422C One of three alternate beta-subunits of the Snf1p kinase complex genetic 1 1 1 Synthetic Growth Defect
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Synthetic Growth Defect
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Synthetic Growth Defect
SOL1 YNR034W Protein with a possible role in tRNA export genetic 1 1 1 Synthetic Growth Defect
SPS19 YNL202W Peroxisomal 2,4-dienoyl-CoA reductase genetic 1 1 1 Synthetic Growth Defect
SQS1 YNL224C Protein that stimulates the ATPase and helicase activities of Prp43p genetic 1 1 1 Synthetic Growth Defect
SRB7 YDR308C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
STE14 YDR410C Farnesyl cysteine-carboxyl methyltransferase genetic 1 1 1 Synthetic Growth Defect
SUI3 YPL237W Beta subunit of the translation initiation factor eIF2 genetic 1 1 1 Synthetic Growth Defect
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Synthetic Growth Defect
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes genetic 1 1 1 Synthetic Growth Defect
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 1 1 1 Synthetic Growth Defect
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Synthetic Growth Defect
TAT1 YBR069C Amino acid transporter for valine, leucine, isoleucine, and tyrosine genetic 1 1 1 Synthetic Growth Defect
TRM112 YNR046W Protein involved in methylation of tRNA, rRNA, and translation factors genetic 1 1 1 Synthetic Growth Defect
TYW1 YPL207W Iron-sulfur protein required for synthesis of wybutosine modified tRNA genetic 1 1 1 Synthetic Growth Defect
UBC5 YDR059C Ubiquitin-conjugating enzyme genetic 1 1 1 Synthetic Growth Defect
UGA2 YBR006W Succinate semialdehyde dehydrogenase genetic 1 1 1 Synthetic Growth Defect
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Synthetic Growth Defect
VHS2 YIL135C Regulator of septin dynamics genetic 1 1 1 Synthetic Growth Defect
XBP1 YIL101C Transcriptional repressor genetic 1 1 1 Synthetic Growth Defect
YBR197C YBR197C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YBR219C YBR219C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YBR242W YBR242W 5'-deoxynucleotidase involved in deoxyribonucleoside monophosphate deg genetic 1 1 1 Synthetic Growth Defect
YBR285W YBR285W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YCR050C YCR050C Non-essential protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YDL144C YDL144C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YDR124W YDR124W Mitochondrial protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YDR249C YDR249C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MGP12 YDR286C Mitochondrial protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YFH1 YDL120W Mitochondrial matrix iron chaperone genetic 1 1 1 Synthetic Growth Defect
YGP1 YNL160W Cell wall-related secretory glycoprotein genetic 1 1 1 Synthetic Growth Defect
YHC3 YJL059W Protein required for the ATP-dependent transport of arginine genetic 1 1 1 Synthetic Growth Defect
YIH1 YCR059C Negative regulator of eIF2 kinase Gcn2p genetic 1 1 1 Synthetic Growth Defect
YIL165C YIL165C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YJL027C YJL027C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Synthetic Growth Defect
YLR257W YLR257W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
RTC4 YNL254C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YNR048W YNR048W Potential noncatalytic subunit for phospholipid translocase Dnf3p genetic 1 1 1 Synthetic Growth Defect
YPT11 YNL304W Rab GTPase genetic 1 1 1 Synthetic Growth Defect
YPT35 YHR105W Endosomal protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YRO2 YBR054W Protein with a putative role in response to acid stress genetic 1 1 1 Synthetic Growth Defect
SPS100 YHR139C Protein required for spore wall maturation genetic 1 1 1 Synthetic Growth Defect
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Suppression
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Positive Genetic
IPI1 YHR085W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Positive Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Positive Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Positive Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
RPB5 YBR154C RNA polymerase subunit ABC27 genetic 1 1 1 Negative Genetic
RRP42 YDL111C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
KOG1 YHR186C Subunit of TORC1 genetic 1 1 1 Negative Genetic
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Negative Genetic
URB2 YJR041C Protein required for normal metabolism of the rRNA primary transcript genetic 1 1 1 Negative Genetic
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Negative Genetic
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) genetic 1 1 1 Negative Genetic
STT4 YLR305C Phosphatidylinositol-4-kinase genetic 1 1 1 Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
TOP2 YNL088W Topoisomerase II genetic 1 1 1 Negative Genetic
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 1 1 1 Negative Genetic
RLI1 YDR091C Essential Fe-S protein genetic 1 1 1 Negative Genetic
UTP5 YDR398W Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
TAH11 YJR046W DNA replication licensing factor genetic 1 1 1 Negative Genetic
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 1 1 1 Negative Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
ISC10 YER180C Meiosis-specific MAPK inhibitor genetic 1 1 1 Negative Genetic
RSM27 YGR215W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
YJR124C YJR124C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Negative Genetic
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Negative Genetic
LDH1 YBR204C Serine hydrolase genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
YDR222W YDR222W Protein of unknown function genetic 1 1 1 Negative Genetic
MNT2 YGL257C Mannosyltransferase genetic 1 1 1 Negative Genetic
MPC2 YHR162W Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) genetic 1 1 1 Negative Genetic
YNL046W YNL046W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation genetic 1 1 1 Negative Genetic
PRM3 YPL192C Protein required for nuclear envelope fusion during karyogamy genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
YKL091C YKL091C Putative phosphatidylinositol/phosphatidylcholine transfer protein genetic 1 1 1 Positive Genetic
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
UBP12 YJL197W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Positive Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
BUD3 YCL014W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 1 1 1 Affinity Capture-MS
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Synthetic Growth Defect
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase physical 1 1 1 Affinity Capture-MS
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity genetic 1 1 1 Synthetic Growth Defect
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex genetic 1 1 1 Synthetic Growth Defect
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 1 1 1 Synthetic Growth Defect
BLM10 YFL007W Proteasome activator physical 1 1 1 Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Synthetic Growth Defect
CPA2 YJR109C Large subunit of carbamoyl phosphate synthetase physical 1 1 1 Affinity Capture-MS
GPM1 YKL152C Tetrameric phosphoglycerate mutase physical 1 1 1 Affinity Capture-MS
GPM1 YKL152C Tetrameric phosphoglycerate mutase genetic 1 1 1 Synthetic Growth Defect
ADE57 YGL234W Bifunctional enzyme of 'de novo' purine nucleotide pathway physical 1 1 1 Affinity Capture-MS
ADE57 YGL234W Bifunctional enzyme of 'de novo' purine nucleotide pathway genetic 1 1 1 Synthetic Growth Defect
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Synthetic Growth Defect
FYV8 YGR196C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ADE3 YGR204W Cytoplasmic trifunctional enzyme physical 1 1 1 Affinity Capture-MS
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 1 1 1 Synthetic Growth Defect
DUG1 YFR044C Cys-Gly metallo-di-peptidase physical 1 1 1 Affinity Capture-MS
DUG1 YFR044C Cys-Gly metallo-di-peptidase genetic 1 1 1 Synthetic Growth Defect
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT7 YJL111W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CAM1 YPL048W One of two isoforms of the gamma subunit of eEF1B physical 1 1 1 Affinity Capture-MS
EFB1 YAL003W Translation elongation factor 1 beta physical 1 1 1 Affinity Capture-MS
GLN1 YPR035W Glutamine synthetase (GS) physical 1 1 1 Affinity Capture-MS
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Synthetic Growth Defect
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Synthetic Growth Defect
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA genetic 1 1 1 Synthetic Growth Defect
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) genetic 1 1 1 Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p physical 1 1 1 Affinity Capture-MS
CMS1 YLR003C Putative subunit of the 90S preribosome processome complex genetic 1 1 1 Synthetic Growth Defect
FAR11 YNL127W Protein involved in recovery from cell cycle arrest physical 1 1 1 Affinity Capture-MS
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Synthetic Rescue
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Synthetic Growth Defect
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Dosage Rescue
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen physical 1 1 1 Affinity Capture-MS
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen genetic 1 1 1 Negative Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization physical 1 1 1 Affinity Capture-MS
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton physical 1 1 1 Affinity Capture-MS
CAR2 YLR438W L-ornithine transaminase (OTAse) physical 1 1 1 Affinity Capture-MS
CAR2 YLR438W L-ornithine transaminase (OTAse) genetic 1 1 1 Synthetic Growth Defect
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Positive Genetic
ACO1 YLR304C Aconitase physical 1 1 1 Affinity Capture-MS
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
ADO1 YJR105W Adenosine kinase physical 1 1 1 Affinity Capture-MS
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase physical 1 1 1 Affinity Capture-MS
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase genetic 1 1 1 Synthetic Growth Defect
DCS1 YLR270W Non-essential hydrolase involved in mRNA decapping physical 1 1 1 Affinity Capture-MS
ARF1 YDL192W ADP-ribosylation factor physical 1 1 1 Affinity Capture-MS
ARF1 YDL192W ADP-ribosylation factor genetic 1 1 1 Synthetic Growth Defect
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Synthetic Growth Defect
AIM2 YAL049C Cytoplasmic protein involved in mitochondrial function or organization physical 1 1 1 Affinity Capture-MS
AIM2 YAL049C Cytoplasmic protein involved in mitochondrial function or organization genetic 1 1 1 Synthetic Growth Defect
BUB2 YMR055C Mitotic exit network regulator genetic 1 1 1 Synthetic Growth Defect
AHP1 YLR109W Thiol-specific peroxiredoxin physical 1 1 1 Affinity Capture-MS
CNA1 YLR433C Calcineurin A physical 1 1 1 Affinity Capture-Western
CMP2 YML057W Calcineurin A physical 1 1 1 Affinity Capture-Western
CMP2 YML057W Calcineurin A genetic 1 1 1 Dosage Rescue
DPS1 YLL018C Aspartyl-tRNA synthetase, primarily cytoplasmic physical 1 1 1 Affinity Capture-MS
DPS1 YLL018C Aspartyl-tRNA synthetase, primarily cytoplasmic genetic 1 1 1 Synthetic Growth Defect
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein physical 1 1 1 Affinity Capture-MS
FAA4 YMR246W Long chain fatty acyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
ARO4 YBR249C 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase physical 1 1 1 Affinity Capture-MS
DIG2 YDR480W MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Affinity Capture-MS
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) genetic 1 1 1 Synthetic Growth Defect
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) genetic 1 1 1 Synthetic Growth Defect
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Synthetic Growth Defect
CMK1 YFR014C Calmodulin-dependent protein kinase genetic 1 1 1 Synthetic Growth Defect
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Synthetic Growth Defect
AMF1 YOR378W Low affinity NH4+ transporter genetic 1 1 1 Synthetic Growth Defect
ADK1 YDR226W Adenylate kinase, required for purine metabolism physical 1 1 1 Affinity Capture-MS
ADK1 YDR226W Adenylate kinase, required for purine metabolism genetic 1 1 1 Synthetic Growth Defect
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization physical 1 1 1 Affinity Capture-MS
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Synthetic Growth Defect
GPD2 YOL059W NAD-dependent glycerol 3-phosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
GPD2 YOL059W NAD-dependent glycerol 3-phosphate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
ATG42 YBR139W Vacuolar serine-type carboxypeptidase physical 1 1 1 Affinity Capture-MS
CYC8 YBR112C General transcriptional co-repressor genetic 1 1 1 Synthetic Growth Defect
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase physical 1 1 1 Affinity Capture-MS
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase genetic 1 1 1 Synthetic Growth Defect
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Synthetic Growth Defect
APT1 YML022W Adenine phosphoribosyltransferase physical 1 1 1 Affinity Capture-MS
ACS2 YLR153C Acetyl-coA synthetase isoform physical 1 1 1 Affinity Capture-MS
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 1 1 1 Negative Genetic
ERG10 YPL028W Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) physical 1 1 1 Affinity Capture-MS
FUM1 YPL262W Fumarase physical 1 1 1 Affinity Capture-MS
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
HEM15 YOR176W Ferrochelatase physical 1 1 1 Affinity Capture-MS
ERG1 YGR175C Squalene epoxidase physical 1 1 1 Affinity Capture-MS
ERG1 YGR175C Squalene epoxidase genetic 1 1 1 Synthetic Growth Defect
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein physical 1 1 1 Affinity Capture-MS
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III physical 1 1 1 Affinity Capture-MS
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III genetic 1 1 1 Synthetic Growth Defect
CDC60 YPL160W Cytosolic leucyl tRNA synthetase physical 1 1 1 Affinity Capture-MS
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase physical 1 1 1 Affinity Capture-MS
ERG20 YJL167W Farnesyl pyrophosphate synthetase physical 1 1 1 Affinity Capture-MS
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
GPN3 YLR243W Putative GTPase with a role in biogenesis of RNA pol II and polIII genetic 1 1 1 Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 1 1 1 Synthetic Growth Defect
ERG6 YML008C Delta(24)-sterol C-methyltransferase physical 1 1 1 Affinity Capture-MS
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
CTF13 YMR094W Subunit of the CBF3 complex genetic 1 1 1 Synthetic Growth Defect
ADD66 YKL206C Protein involved in 20S proteasome assembly physical 1 1 1 Affinity Capture-MS
ADD66 YKL206C Protein involved in 20S proteasome assembly genetic 1 1 1 Synthetic Growth Defect
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Synthetic Growth Defect
GAL7 YBR018C Galactose-1-phosphate uridyl transferase genetic 1 1 1 Synthetic Growth Defect
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Negative Genetic
GPG1 YGL121C Proposed gamma subunit of the heterotrimeric G protein genetic 1 1 1 Synthetic Growth Defect
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Synthetic Growth Defect
FAA1 YOR317W Long chain fatty acyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
ACS1 YAL054C Acetyl-coA synthetase isoform physical 1 1 1 Affinity Capture-MS
ADE17 YMR120C Enzyme of 'de novo' purine biosynthesis physical 1 1 1 Affinity Capture-MS
AIP5 YFR016C Protein that positively regulates actin assembly genetic 1 1 1 Synthetic Growth Defect
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) physical 1 1 1 Affinity Capture-MS
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Growth Defect
GSY1 YFR015C Glycogen synthase genetic 1 1 1 Synthetic Growth Defect
APA1 YCL050C AP4A phosphorylase physical 1 1 1 Affinity Capture-MS
ASR1 YPR093C Ubiquitin ligase that modifies and regulates RNA Pol II physical 1 1 1 Affinity Capture-MS
GDT1 YBR187W Calcium and manganese transporter with higher affinity for Ca2+ genetic 1 1 1 Synthetic Growth Defect
CTR1 YPR124W High-affinity copper transporter of plasma membrane genetic 1 1 1 Synthetic Growth Defect
DUT1 YBR252W Deoxyuridine triphosphate diphosphatase (dUTPase) genetic 1 1 1 Synthetic Growth Defect
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
AVT2 YEL064C Putative transporter genetic 1 1 1 Synthetic Growth Defect
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Biochemical Activity
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Negative Genetic
CBR1 YIL043C Cytochrome b reductase and NADH-dependent reductase for Dph3p physical 1 1 1 Affinity Capture-MS
CSC1 YLR241W Calcium permeable gated cation channel genetic 1 1 1 Synthetic Growth Defect
ARA1 YBR149W NADP+ dependent arabinose dehydrogenase physical 1 1 1 Affinity Capture-MS
ADE6 YGR061C Formylglycinamidine-ribonucleotide (FGAM)-synthetase physical 1 1 1 Affinity Capture-MS
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
CYS3 YAL012W Cystathionine gamma-lyase physical 1 1 1 Affinity Capture-MS
CMG1 YLR271W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ARO9 YHR137W Aromatic aminotransferase II genetic 1 1 1 Synthetic Growth Defect
GDH2 YDL215C NAD(+)-dependent glutamate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Synthetic Rescue
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Positive Genetic
CSM2 YIL132C Subunit of the Shu complex (aka PCSS complex) genetic 1 1 1 Synthetic Growth Defect
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Synthetic Growth Defect
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase physical 1 1 1 Affinity Capture-MS
ADE8 YDR408C Phosphoribosyl-glycinamide transformylase physical 1 1 1 Affinity Capture-MS
ALR1 YOL130W Plasma membrane Mg(2+) transporter genetic 1 1 1 Negative Genetic
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Growth Defect
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Synthetic Growth Defect
DAL82 YNL314W Positive regulator of allophanate inducible genes genetic 1 1 1 Synthetic Growth Defect
GDH1 YOR375C NADP(+)-dependent glutamate dehydrogenase physical 1 1 1 Affinity Capture-MS
ARG81 YML099C Zinc finger transcription factor involved in arginine-responsive genes genetic 1 1 1 Synthetic Growth Defect
ATG19 YOL082W Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway physical 1 1 1 Affinity Capture-MS
HAA1 YPR008W Transcriptional activator involved in adaptation to weak acid stress genetic 1 1 1 Negative Genetic
ATG36 YJL185C Pex3p interacting protein, required for pexophagy genetic 1 1 1 Synthetic Growth Defect
DON1 YDR273W Meiosis-specific component of the spindle pole body genetic 1 1 1 Synthetic Growth Defect
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway physical 1 1 1 Affinity Capture-MS
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Negative Genetic
ADY3 YDL239C Protein required for spore wall formation genetic 1 1 1 Synthetic Growth Defect
CNL1 YDR357C Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Synthetic Growth Defect
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance physical 1 1 1 Affinity Capture-MS
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance genetic 1 1 1 Synthetic Growth Defect
CUB1 YPL260W Conserved fungal gene linked to DNA repair and proteasome function physical 1 1 1 Affinity Capture-MS
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
CDC26 YFR036W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Synthetic Growth Defect
CWC15 YDR163W Non-essential protein involved in pre-mRNA splicing genetic 1 1 1 Synthetic Growth Defect
COG7 YGL005C Component of the conserved oligomeric Golgi complex physical 1 1 1 Affinity Capture-Western
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
COG6 YNL041C Component of the conserved oligomeric Golgi complex physical 1 1 1 Affinity Capture-MS
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
COG5 YNL051W Component of the conserved oligomeric Golgi complex physical 1 1 1 Affinity Capture-Western
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
GRC3 YLL035W Polynucleotide kinase present on rDNA genetic 1 1 1 Negative Genetic
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Synthetic Growth Defect
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
CDC31 YOR257W Calcium-binding component of the spindle pole body (SPB) half-bridge genetic 1 1 1 Synthetic Growth Defect
HPC2 YBR215W Subunit of the HIR complex genetic 1 1 1 Synthetic Growth Defect
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
ALF1 YNL148C Alpha-tubulin folding protein physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes genetic 1 1 1 Synthetic Growth Defect
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Synthetic Growth Defect
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Synthetic Growth Defect
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion genetic 1 1 1 Synthetic Growth Defect
HNT1 YDL125C Adenosine 5'-monophosphoramidase genetic 1 1 1 Synthetic Growth Defect
ATS1 YAL020C Protein required for modification of wobble nucleosides in tRNA genetic 1 1 1 Synthetic Growth Defect
FIG4 YNL325C Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase genetic 1 1 1 Synthetic Growth Defect
DPH2 YKL191W Protein required for synthesis of diphthamide genetic 1 1 1 Synthetic Growth Defect
DPH1 YIL103W Protein required for synthesis of diphthamide physical 1 1 1 Affinity Capture-MS
HRB1 YNL004W Poly(A+) RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding physical 1 1 1 Affinity Capture-MS
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding genetic 1 1 1 Synthetic Growth Defect
EMP47 YFL048C Integral membrane component of ER-derived COPII-coated vesicles physical 1 1 1 Affinity Capture-MS
EMP47 YFL048C Integral membrane component of ER-derived COPII-coated vesicles genetic 1 1 1 Synthetic Growth Defect
CCP1 YKR066C Mitochondrial cytochrome-c peroxidase physical 1 1 1 Affinity Capture-MS
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p genetic 1 1 1 Synthetic Growth Defect
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p physical 1 1 1 Affinity Capture-MS
FBP1 YLR377C Fructose-1,6-bisphosphatase physical 1 1 1 Affinity Capture-MS
EMC5 YIL027C Member of conserved ER transmembrane complex genetic 1 1 1 Synthetic Growth Defect
ARG80 YMR042W Transcription factor involved in regulating arginine-responsive genes genetic 1 1 1 Synthetic Growth Defect
ESC1 YMR219W Protein involved in telomeric silencing physical 1 1 1 Affinity Capture-MS
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Synthetic Growth Defect
GAL1 YBR020W Galactokinase physical 1 1 1 Affinity Capture-Western
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator genetic 1 1 1 Synthetic Growth Defect
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 1 1 1 Synthetic Growth Defect
BCH1 YMR237W Member of the ChAPs family (Chs5p-Arf1p-binding proteins) physical 1 1 1 Affinity Capture-MS
FBP26 YJL155C Fructose-2,6-bisphosphatase, required for glucose metabolism genetic 1 1 1 Synthetic Growth Defect
EMA17 YIL029C Protein involved in targeting mitochondrial membrane protein precursor genetic 1 1 1 Synthetic Growth Defect
COQ1 YBR003W Hexaprenyl pyrophosphate synthetase genetic 1 1 1 Synthetic Growth Defect
DPH6 YLR143W Diphthamide synthetase genetic 1 1 1 Synthetic Growth Defect
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Synthetic Growth Defect
GFD2 YCL036W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Synthetic Growth Defect
ATP1 YBL099W Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-MS
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Synthetic Growth Defect
HMS1 YOR032C bHLH protein with similarity to myc-family transcription factors genetic 1 1 1 Synthetic Growth Defect
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 1 1 1 Synthetic Growth Defect
GAT1 YFL021W Transcriptional activator of nitrogen catabolite repression genes genetic 1 1 1 Synthetic Growth Defect
APN2 YBL019W Class II abasic (AP) endonuclease involved in repair of DNA damage genetic 1 1 1 Synthetic Growth Defect
COX17 YLL009C Copper metallochaperone that transfers copper to Sco1p and Cox11p genetic 1 1 1 Synthetic Growth Defect
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) physical 1 1 1 Affinity Capture-MS
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) genetic 1 1 1 Synthetic Growth Defect
ERV29 YGR284C Protein localized to COPII-coated vesicles physical 1 1 1 Affinity Capture-MS
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Synthetic Growth Defect
CAP2 YIL034C Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) physical 1 1 1 Affinity Capture-MS
ETT1 YOR051C Nuclear protein that inhibits replication of Brome mosaic virus physical 1 1 1 Affinity Capture-MS
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Synthetic Growth Defect
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway genetic 1 1 1 Synthetic Growth Defect
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily physical 1 1 1 Affinity Capture-MS
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Synthetic Growth Defect
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 1 1 1 Dosage Rescue
DYS1 YHR068W Deoxyhypusine synthase physical 1 1 1 Affinity Capture-MS
DYS1 YHR068W Deoxyhypusine synthase genetic 1 1 1 Negative Genetic
ERV14 YGL054C COPII-coated vesicle protein physical 1 1 1 Affinity Capture-MS
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 physical 1 1 1 Affinity Capture-MS
ASG1 YIL130W Zinc cluster protein proposed to be a transcriptional regulator genetic 1 1 1 Synthetic Growth Defect
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane physical 1 1 1 Affinity Capture-MS
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Synthetic Growth Defect
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Synthetic Growth Defect
ARO8 YGL202W Aromatic aminotransferase I physical 1 1 1 Affinity Capture-MS
EMC6 YLL014W Member of conserved ER transmembrane complex genetic 1 1 1 Synthetic Growth Defect
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 1 1 1 Synthetic Growth Defect
CIT1 YNR001C Mitochondrial citrate synthase genetic 1 1 1 Synthetic Growth Defect
ADE1 YAR015W N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase physical 1 1 1 Affinity Capture-MS
ADE1 YAR015W N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase genetic 1 1 1 Synthetic Growth Defect
ASF2 YDL197C Anti-silencing protein genetic 1 1 1 Synthetic Growth Defect
FMO1 YHR176W Flavin-containing monooxygenase genetic 1 1 1 Synthetic Growth Defect
FRK1 YPL141C Protein kinase of unknown cellular role genetic 1 1 1 Synthetic Growth Defect
GEF1 YJR040W Voltage-gated chloride channel genetic 1 1 1 Synthetic Growth Defect
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription physical 1 1 1 Affinity Capture-MS
COQ3 YOL096C O-methyltransferase genetic 1 1 1 Synthetic Growth Defect
ASG7 YJL170C Protein that regulates signaling from G protein beta subunit Ste4p genetic 1 1 1 Synthetic Growth Defect
DUS3 YLR401C Dihydrouridine synthase genetic 1 1 1 Synthetic Growth Defect
CST26 YBR042C Acyltransferase genetic 1 1 1 Synthetic Growth Defect
HEH2 YDR458C Inner nuclear membrane (INM) protein genetic 1 1 1 Synthetic Growth Defect
CAN1 YEL063C Plasma membrane arginine permease genetic 1 1 1 Synthetic Growth Defect
AIM45 YPR004C Putative ortholog of mammalian ETF-alpha physical 1 1 1 Affinity Capture-MS
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Synthetic Growth Defect
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Synthetic Growth Defect
EXP1 YDL121C A cargo receptor protein for Pma1p physical 1 1 1 Affinity Capture-MS
CUE1 YMR264W Ubiquitin-binding protein genetic 1 1 1 Synthetic Growth Defect
BDH1 YAL060W NAD-dependent (R,R)-butanediol dehydrogenase physical 1 1 1 Affinity Capture-MS
GLK1 YCL040W Glucokinase physical 1 1 1 Affinity Capture-MS
AYT1 YLL063C Acetyltransferase genetic 1 1 1 Synthetic Growth Defect
GLO4 YOR040W Mitochondrial glyoxalase II genetic 1 1 1 Negative Genetic
ARI1 YGL157W NADPH-dependent aldehyde reductase physical 1 1 1 Affinity Capture-MS
FRE3 YOR381W Ferric reductase genetic 1 1 1 Synthetic Growth Defect
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
FMP23 YBR047W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
FCF2 YLR051C Nucleolar protein involved in the early steps of 35S rRNA processing genetic 1 1 1 Synthetic Growth Defect
AEP3 YPL005W Peripheral mitochondrial inner membrane protein genetic 1 1 1 Synthetic Growth Defect
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase physical 1 1 1 Affinity Capture-MS
CRS1 YNL247W Cysteinyl-tRNA synthetase genetic 1 1 1 Synthetic Growth Defect
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy genetic 1 1 1 Synthetic Growth Defect
CSR1 YLR380W Phosphatidylinositol transfer protein genetic 1 1 1 Synthetic Growth Defect
CHA1 YCL064C Catabolic L-serine (L-threonine) deaminase physical 1 1 1 Affinity Capture-MS
GRE3 YHR104W Aldose reductase genetic 1 1 1 Synthetic Growth Defect
ALD6 YPL061W Cytosolic aldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
ALD6 YPL061W Cytosolic aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Synthetic Growth Defect
CYB5 YNL111C Cytochrome b5 genetic 1 1 1 Synthetic Growth Defect
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 1 1 1 Synthetic Growth Defect
ANB1 YJR047C Translation elongation factor eIF-5A genetic 1 1 1 Synthetic Growth Defect
AQY3 YFL054C Putative channel-like protein genetic 1 1 1 Synthetic Growth Defect
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Synthetic Growth Defect
AIM26 YKL037W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ECM3 YOR092W Non-essential protein of unknown function genetic 1 1 1 Synthetic Growth Defect
HFD1 YMR110C Dehydrogenase involved in ubiquinone and sphingolipid metabolism physical 1 1 1 Affinity Capture-MS
DSF1 YEL070W Mannitol dehydrogenase physical 1 1 1 Affinity Capture-MS
FLO11 YIR019C GPI-anchored cell surface glycoprotein (flocculin) genetic 1 1 1 Phenotypic Suppression
EFM6 YNL024C Putative S-adenosylmethionine-dependent lysine methyltransferase genetic 1 1 1 Synthetic Growth Defect
ADE12 YNL220W Adenylosuccinate synthase physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
GTT3 YEL017W Protein of unknown function may be involved in glutathione metabolism genetic 1 1 1 Synthetic Growth Defect
GIP4 YAL031C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p genetic 1 1 1 Synthetic Growth Defect
DNF1 YER166W Aminophospholipid translocase (flippase) genetic 1 1 1 Synthetic Growth Defect
GLN4 YOR168W Glutamine tRNA synthetase physical 1 1 1 Affinity Capture-MS
FAS1 YKL182W Beta subunit of fatty acid synthetase physical 1 1 1 Affinity Capture-MS
EGH1 YIR007W Steryl-beta-glucosidase with broad specificity for aglycones physical 1 1 1 Affinity Capture-MS
COA3 YJL062W-A Mitochondrial protein required for cytochrome c oxidase assembly physical 1 1 1 Affinity Capture-MS
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Synthetic Growth Defect
GVP36 YIL041W BAR domain protein that localizes to early and late Golgi vesicles physical 1 1 1 Affinity Capture-MS
GVP36 YIL041W BAR domain protein that localizes to early and late Golgi vesicles genetic 1 1 1 Synthetic Growth Defect
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 1 1 1 Synthetic Growth Defect
ABP140 YOR239W AdoMet-dependent tRNA methyltransferase and actin binding protein genetic 1 1 1 Synthetic Growth Defect
ALR2 YFL050C Probable Mg(2+) transporter genetic 1 1 1 Synthetic Growth Defect
CMK2 YOL016C Calmodulin-dependent protein kinase physical 1 1 1 Affinity Capture-MS
DFM1 YDR411C Endoplasmic reticulum (ER) localized protein genetic 1 1 1 Synthetic Growth Defect
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Synthetic Growth Defect
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Synthetic Growth Defect
AGE2 YIL044C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector genetic 1 1 1 Synthetic Growth Defect
CYC3 YAL039C Cytochrome c heme lyase (holocytochrome c synthase) genetic 1 1 1 Synthetic Growth Defect
GGC1 YDL198C Mitochondrial GTP/GDP transporter genetic 1 1 1 Synthetic Growth Defect
ENT4 YLL038C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
HIS5 YIL116W Histidinol-phosphate aminotransferase physical 1 1 1 Affinity Capture-MS
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Synthetic Growth Defect
ALG13 YGL047W Catalytic component of UDP-GlcNAc transferase genetic 1 1 1 Synthetic Growth Defect
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Synthetic Growth Defect
ASI1 YMR119W Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Synthetic Growth Defect
HEM2 YGL040C Aminolevulinate dehydratase physical 1 1 1 Affinity Capture-MS
CYC2 YOR037W Mitochondrial peripheral inner membrane protein genetic 1 1 1 Synthetic Growth Defect
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Negative Genetic
BXI1 YNL305C Protein involved in apoptosis genetic 1 1 1 Synthetic Growth Defect
DFG16 YOR030W Probable multiple transmembrane protein genetic 1 1 1 Synthetic Growth Defect
FPY1 YMR178W FAD pyrophosphatase physical 1 1 1 Affinity Capture-MS
GPX2 YBR244W Phospholipid hydroperoxide glutathione peroxidase physical 1 1 1 Affinity Capture-MS
GRX3 YDR098C Glutathione-dependent oxidoreductase physical 1 1 1 Affinity Capture-MS
BAP2 YBR068C High-affinity leucine permease genetic 1 1 1 Synthetic Growth Defect
FCY2 YER056C Purine-cytosine permease genetic 1 1 1 Synthetic Growth Defect
DPP1 YDR284C Diacylglycerol pyrophosphate (DGPP) phosphatase physical 1 1 1 Affinity Capture-MS
GPM2 YDL021W Nonfunctional homolog of Gpm1p phosphoglycerate mutase genetic 1 1 1 Synthetic Growth Defect
HNT2 YDR305C Dinucleoside triphosphate hydrolase genetic 1 1 1 Synthetic Growth Defect
ARO10 YDR380W Phenylpyruvate decarboxylase physical 1 1 1 Affinity Capture-MS
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 1 1 1 Synthetic Growth Defect
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Synthetic Growth Defect
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Synthetic Growth Defect
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Synthetic Growth Defect
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 1 1 1 Synthetic Growth Defect
CTT1 YGR088W Cytosolic catalase T physical 1 1 1 Affinity Capture-MS
ATG15 YCR068W Phospholipase genetic 1 1 1 Synthetic Growth Defect
HAL9 YOL089C Putative transcription factor containing a zinc finger genetic 1 1 1 Synthetic Growth Defect
GRX2 YDR513W Cytoplasmic glutaredoxin physical 1 1 1 Affinity Capture-MS
DAK1 YML070W Dihydroxyacetone kinase physical 1 1 1 Affinity Capture-MS
CCW14 YLR390W-A Covalently linked cell wall glycoprotein genetic 1 1 1 Synthetic Growth Defect
DAT1 YML113W DNA binding protein that recognizes oligo(dA).oligo(dT) tracts genetic 1 1 1 Synthetic Growth Defect
CTS1 YLR286C Endochitinase genetic 1 1 1 Synthetic Growth Defect
GPI18 YBR004C Functional ortholog of human PIG-V genetic 1 1 1 Synthetic Growth Defect
BRE4 YDL231C Zinc finger protein containing five transmembrane domains genetic 1 1 1 Synthetic Growth Defect
DLD1 YDL174C Major mitochondrial D-lactate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
GRE2 YOL151W 3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase physical 1 1 1 Affinity Capture-MS
HIS1 YER055C ATP phosphoribosyltransferase physical 1 1 1 Affinity Capture-MS
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) physical 1 1 1 Affinity Capture-MS
GRX6 YDL010W Cis-Golgi localized monothiol glutaredoxin, binds Fe-S cluster genetic 1 1 1 Synthetic Growth Defect
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Growth Defect
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Synthetic Growth Defect
ERG12 YMR208W Mevalonate kinase physical 1 1 1 Reconstituted Complex
EFM4 YIL064W Lysine methyltransferase genetic 1 1 1 Synthetic Growth Defect
CPR8 YNR028W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Synthetic Growth Defect
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 1 1 1 Synthetic Growth Defect
DIT2 YDR402C N-formyltyrosine oxidase genetic 1 1 1 Synthetic Growth Defect
ALD3 YMR169C Cytoplasmic aldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
GIT1 YCR098C Plasma membrane permease genetic 1 1 1 Synthetic Growth Defect
ERJ5 YFR041C Type I membrane protein with a J domain genetic 1 1 1 Synthetic Growth Defect
ARR2 YPR200C Arsenate reductase required for arsenate resistance genetic 1 1 1 Negative Genetic
BMT6 YLR063W Methyltransferase required for m3U2843 methylation of the 25S rRNA genetic 1 1 1 Synthetic Growth Defect
AIM36 YMR157C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
AIM9 YER080W Protein of unknown function physical 1 1 1 Affinity Capture-MS
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Synthetic Growth Defect
FAT3 YKL187C Protein required for fatty acid uptake genetic 1 1 1 Synthetic Growth Defect
ECM8 YBR076W Non-essential protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ECM23 YPL021W Non-essential protein of unconfirmed function genetic 1 1 1 Synthetic Growth Defect