| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
physical |
23 |
5 |
18 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Reconstituted Complex |
| RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
physical |
12 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
11 |
2 |
9 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
11 |
3 |
8 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
11 |
3 |
8 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
physical |
10 |
4 |
8 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
10 |
2 |
5 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
9 |
2 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex |
| CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
physical |
9 |
3 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Two-hybrid |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
9 |
3 |
6 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
physical |
9 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex |
| HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
9 |
3 |
4 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
physical |
8 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
8 |
3 |
7 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
8 |
2 |
7 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
8 |
3 |
6 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
8 |
3 |
6 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
8 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
physical |
8 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
8 |
2 |
6 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
7 |
3 |
6 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
7 |
2 |
6 |
Negative Genetic, Positive Genetic, Positive Genetic, Negative Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
physical |
7 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
7 |
1 |
6 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
7 |
2 |
5 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
7 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
7 |
3 |
4 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
7 |
3 |
4 |
Synthetic Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
| SWC3 |
YAL011W |
Protein of unknown function |
genetic |
7 |
2 |
4 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
7 |
2 |
4 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
6 |
3 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Rescue, Negative Genetic |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
6 |
3 |
6 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Negative Genetic, Negative Genetic |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
6 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
6 |
2 |
6 |
Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
6 |
3 |
5 |
Synthetic Rescue, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Phenotypic Suppression |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
6 |
2 |
5 |
Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
6 |
2 |
5 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
6 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
6 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
physical |
6 |
2 |
4 |
Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Two-hybrid |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
6 |
2 |
4 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RXT3 |
YDL076C |
Component of the Rpd3L histone deacetylase complex |
physical |
6 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
6 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
6 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
5 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
5 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
5 |
3 |
4 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
5 |
2 |
4 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect |
| ERG26 |
YGL001C |
C-3 sterol dehydrogenase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
physical |
5 |
3 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
5 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-RNA |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
5 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SAS2 |
YMR127C |
Histone acetyltransferase (HAT) catalytic subunit of the SAS complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SAS4 |
YDR181C |
Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
genetic |
5 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
5 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
4 |
4 |
4 |
Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Suppression, Negative Genetic |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
4 |
2 |
4 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
4 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
4 |
2 |
4 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic |
| SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
4 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
4 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic, Negative Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic |
| BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Negative Genetic, Synthetic Lethality, Synthetic Lethality |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| TIM13 |
YGR181W |
Mitochondrial intermembrane space protein |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
4 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
4 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SCO2 |
YBR024W |
Protein anchored to mitochondrial inner membrane |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| DTR1 |
YBR180W |
Putative dityrosine transporter of the major facilitator superfamily |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
4 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| ADA2 |
YDR448W |
Transcription coactivator |
genetic |
4 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
3 |
3 |
3 |
Positive Genetic, Phenotypic Suppression, Synthetic Rescue |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Rescue |
| SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| HHT1 |
YBR010W |
Histone H3 |
physical |
3 |
2 |
3 |
Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS |
| ASH1 |
YKL185W |
Component of the Rpd3L histone deacetylase complex |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
| NSI1 |
YDR026C |
RNA polymerase I termination factor |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BDF2 |
YDL070W |
Protein involved in transcription initiation |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| TRK1 |
YJL129C |
Component of the Trk1p-Trk2p potassium transport system |
genetic |
3 |
1 |
3 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
| THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| YPT31 |
YER031C |
Rab family GTPase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| INO2 |
YDR123C |
Transcription factor |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| OAF1 |
YAL051W |
Oleate-activated transcription factor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SAS5 |
YOR213C |
Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
physical |
3 |
3 |
2 |
Affinity Capture-MS, Reconstituted Complex, Two-hybrid |
| BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality |
| SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
| NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect |
| NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
| RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
3 |
2 |
2 |
Positive Genetic, Synthetic Rescue, Synthetic Rescue |
| MSC1 |
YML128C |
Protein of unknown function |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MDM10 |
YAL010C |
Subunit of both the ERMES and the SAM complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
3 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| YBR238C |
YBR238C |
Mitochondrial membrane protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| XYL2 |
YLR070C |
Xylitol dehydrogenase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TAF8 |
YML114C |
TFIID subunit (65 kDa) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SNZ1 |
YMR096W |
Subunit of a two-component pyridoxal-5'-phosphate synthase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TEP1 |
YNL128W |
PTEN homolog with no demonstrated inositol lipid phosphatase activity |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TKL1 |
YPR074C |
Transketolase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PSR1 |
YLL010C |
Plasma membrane-associated protein phosphatase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GID8 |
YMR135C |
Subunit of GID Complex, binds strongly to central component Vid30p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
3 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| GBP2 |
YCL011C |
Poly(A+) RNA-binding protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| KTI12 |
YKL110C |
Protein that plays a role in modification of tRNA wobble nucleosides |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PEX12 |
YMR026C |
C3HC4-type RING-finger peroxin and E3 ubiquitin ligase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CHA1 |
YCL064C |
Catabolic L-serine (L-threonine) deaminase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| IZH3 |
YLR023C |
Membrane protein involved in zinc ion homeostasis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RTC6 |
YPL183W-A |
Protein involved in translation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GIC2 |
YDR309C |
Rho-family GTPase interacting protein and Cdc42p effector |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
| HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
| TOP2 |
YNL088W |
Topoisomerase II |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
| MIH1 |
YMR036C |
Protein tyrosine phosphatase |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| AKR2 |
YOR034C |
Ankyrin repeat-containing protein |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Reconstituted Complex |
| DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Suppression |
| MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
| HHT2 |
YNL031C |
Histone H3 |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex |
| MSC2 |
YDR205W |
Endoplasmic reticulum zinc transporter |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
| ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| NTO1 |
YPR031W |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SAP190 |
YKR028W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RSC58 |
YLR033W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HGH1 |
YGR187C |
Chaperone protein for translation factor eEF2 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GCN2 |
YDR283C |
Protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HHF1 |
YBR009C |
Histone H4 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| IOC3 |
YFR013W |
Subunit of the Isw1a complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MIS1 |
YBR084W |
Mitochondrial C1-tetrahydrofolate synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| HTA2 |
YBL003C |
Histone H2A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ABF2 |
YMR072W |
Mitochondrial DNA-binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
| UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| THP1 |
YOL072W |
Nuclear pore-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| WHI4 |
YDL224C |
Putative RNA binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TFG1 |
YGR186W |
TFIIF (Transcription Factor II) largest subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SUT1 |
YGL162W |
Zn(II)2Cys6 family transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SYN8 |
YAL014C |
Endosomal SNARE related to mammalian syntaxin 8 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YBL055C |
YBL055C |
3'-->5' exonuclease and endonuclease with a possible role in apoptosis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YDL157C |
YDL157C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBP16 |
YPL072W |
Deubiquitinating enzyme anchored to the outer mitochondrial membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SUV3 |
YPL029W |
ATP-dependent RNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| URC2 |
YDR520C |
Putative Zn(II)2Cys6 motif containing transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TRX2 |
YGR209C |
Cytoplasmic thioredoxin isoenzyme |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPL245W |
YPL245W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FUN19 |
YAL034C |
Non-essential protein of unknown function |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| OYE2 |
YHR179W |
Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| GCY1 |
YOR120W |
Glycerol dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CIN5 |
YOR028C |
Basic leucine zipper (bZIP) transcription factor of the yAP-1 family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CHZ1 |
YER030W |
Histone chaperone for Htz1p/H2A-H2B dimer |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IKI1 |
YHR187W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DOC1 |
YGL240W |
Processivity factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AMD1 |
YML035C |
AMP deaminase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CTK2 |
YJL006C |
Beta subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC15 |
YGL233W |
Essential 113 kDa subunit of the exocyst complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PDR17 |
YNL264C |
Phosphatidylinositol transfer protein (PITP) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PEX30 |
YLR324W |
ER-resident protein involved in peroxisomal biogenesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HMS1 |
YOR032C |
bHLH protein with similarity to myc-family transcription factors |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HXT1 |
YHR094C |
Low-affinity glucose transporter of the major facilitator superfamily |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MAK31 |
YCR020C-A |
Non-catalytic subunit of N-terminal acetyltransferase of the NatC type |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CYT2 |
YKL087C |
Cytochrome c1 heme lyase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GPI1 |
YGR216C |
Membrane protein involved in the synthesis of GlcNAc-PI |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MTC4 |
YBR255W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FRE7 |
YOL152W |
Putative ferric reductase with similarity to Fre2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FMT1 |
YBL013W |
Methionyl-tRNA formyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PRM6 |
YML047C |
Potassium transporter that mediates K+ influx |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MTC6 |
YHR151C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
physical |
2 |
2 |
1 |
Reconstituted Complex, Two-hybrid |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| RNH1 |
YMR234W |
Ribonuclease H1 |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Phenotypic Enhancement |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| CUB1 |
YPL260W |
Conserved fungal gene linked to DNA repair and proteasome function |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| HOS1 |
YPR068C |
Class I histone deacetylase (HDAC) family member |
physical |
2 |
2 |
1 |
Reconstituted Complex, Two-hybrid |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| RSC2 |
YLR357W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| CYR1 |
YJL005W |
Adenylate cyclase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| MGM101 |
YJR144W |
Protein with a role in mitochondrial DNA recombinational repair |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| SNF8 |
YPL002C |
Component of the ESCRT-II complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| TAM41 |
YGR046W |
Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS20 |
YMR077C |
Myristoylated subunit of the ESCRT-III complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| VPS25 |
YJR102C |
Component of the ESCRT-II complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| SOV1 |
YMR066W |
Mitochondrial protein of unknown function |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| FYV10 |
YIL097W |
Subunit of GID complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| DSS1 |
YMR287C |
3'-5' exoribonuclease |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| HHT1 |
YBR010W |
Histone H3 |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MSS116 |
YDR194C |
Mitochondrial transcription elongation factor |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| OMS1 |
YDR316W |
Protein integral to the mitochondrial membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| GIP1 |
YBR045C |
Meiosis-specific regulatory subunit of the Glc7p protein phosphatase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| RRN11 |
YML043C |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| MCR1 |
YKL150W |
Mitochondrial NADH-cytochrome b5 reductase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| MSE1 |
YOL033W |
Mitochondrial glutamyl-tRNA synthetase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| NPT1 |
YOR209C |
Nicotinate phosphoribosyltransferase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| IRC19 |
YLL033W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| MSS18 |
YPR134W |
Nuclear encoded protein needed for splicing of mitochondrial intron |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DPH5 |
YLR172C |
Methyltransferase required for synthesis of diphthamide |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| COX10 |
YPL172C |
Heme A:farnesyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| HER2 |
YMR293C |
Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PFA4 |
YOL003C |
Palmitoyltransferase with autoacylation activity |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| QDR1 |
YIL120W |
Multidrug transporter of the major facilitator superfamily |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| QRI5 |
YLR204W |
Mitochondrial inner membrane protein |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| RAD61 |
YDR014W |
Subunit of a complex that inhibits sister chromatid cohesion |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| PRS1 |
YKL181W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ADY2 |
YCR010C |
Acetate transporter required for normal sporulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| AGA2 |
YGL032C |
Adhesion subunit of a-agglutinin of a-cells |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| AGA1 |
YNR044W |
Anchorage subunit of a-agglutinin of a-cells |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CAR1 |
YPL111W |
Arginase, catabolizes arginine to ornithine and urea |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ARG1 |
YOL058W |
Arginosuccinate synthetase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YDR341C |
YDR341C |
Arginyl-tRNA synthetase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| BAR1 |
YIL015W |
Aspartyl protease secreted to periplasmic space of mating type a cell |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| NCE103 |
YNL036W |
Carbonic anhydrase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CHA1 |
YCL064C |
Catabolic L-serine (L-threonine) deaminase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CWP1 |
YKL096W |
Cell wall mannoprotein that localizes to birth scars of daughter cells |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YGP1 |
YNL160W |
Cell wall-related secretory glycoprotein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YOR302W |
YOR302W |
CPA1 uORF |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| REH1 |
YLR387C |
Cytoplasmic 60S subunit biogenesis factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ALD3 |
YMR169C |
Cytoplasmic aldehyde dehydrogenase |
regulation |
1 |
1 |
1 |
northern blot evidence |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SGN1 |
YIR001C |
Cytoplasmic RNA-binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TYS1 |
YGR185C |
Cytoplasmic tyrosyl-tRNA synthetase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CTT1 |
YGR088W |
Cytosolic catalase T |
regulation |
1 |
1 |
1 |
northern blot evidence |
| SHM2 |
YLR058C |
Cytosolic serine hydroxymethyltransferase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| URA1 |
YKL216W |
Dihydroorotate dehydrogenase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YDL023C |
YDL023C |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YGR259C |
YGR259C |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YLR041W |
YLR041W |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CTS1 |
YLR286C |
Endochitinase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ERG28 |
YER044C |
Endoplasmic reticulum membrane protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YPL264C |
YPL264C |
Endoplasmic reticulum protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| COS1 |
YNL336W |
Endosomal protein involved in turnover of plasma membrane proteins |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| COS2 |
YBR302C |
Endosomal protein involved in turnover of plasma membrane proteins |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| COS4 |
YFL062W |
Endosomal protein involved in turnover of plasma membrane proteins |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| COS6 |
YGR295C |
Endosomal protein involved in turnover of plasma membrane proteins |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| COS8 |
YHL048W |
Endosomal protein involved in turnover of plasma membrane proteins |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| COS10 |
YNR075W |
Endosomal protein involved in turnover of plasma membrane proteins |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| COS3 |
YML132W |
Endosomal protein involved in turnover of plasma membrane proteins |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ADE17 |
YMR120C |
Enzyme of 'de novo' purine biosynthesis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SIT1 |
YEL065W |
Ferrioxamine B transporter |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FET3 |
YMR058W |
Ferro-O2-oxidoreductase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| FBA1 |
YKL060C |
Fructose 1,6-bisphosphate aldolase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| UGA1 |
YGR019W |
Gamma-aminobutyrate (GABA) transaminase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GLK1 |
YCL040W |
Glucokinase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GPC1 |
YGR149W |
Glycerophosphocholine acyltransferase (GPCAT) |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GOR1 |
YNL274C |
Glyoxylate reductase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TED1 |
YIL039W |
GPI-glycan remodelase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HPF1 |
YOL155C |
Haze-protective mannoprotein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MUP1 |
YGR055W |
High affinity methionine permease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TNA1 |
YGR260W |
High affinity nicotinic acid plasma membrane permease |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HIS5 |
YIL116W |
Histidinol-phosphate aminotransferase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HHT1 |
YBR010W |
Histone H3 |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| IMD2 |
YHR216W |
Inosine monophosphate dehydrogenase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| INO1 |
YJL153C |
Inositol-3-phosphate synthase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SUC2 |
YIL162W |
Invertase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| BNA4 |
YBL098W |
Kynurenine 3-monooxygenase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| LCB3 |
YJL134W |
Long-chain base-1-phosphate phosphatase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TIP1 |
YBR067C |
Major cell wall mannoprotein with possible lipase activity |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MET13 |
YGL125W |
Major isozyme of methylenetetrahydrofolate reductase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| FIT2 |
YOR382W |
Mannoprotein that is incorporated into the cell wall |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FIT3 |
YOR383C |
Mannoprotein that is incorporated into the cell wall |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MFA1 |
YDR461W |
Mating pheromone a-factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| EMC4 |
YGL231C |
Member of conserved ER transmembrane complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CUP1-1 |
YHR053C |
Metallothionein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CUP1-2 |
YHR055C |
Metallothionein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ALD4 |
YOR374W |
Mitochondrial aldehyde dehydrogenase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| NDE1 |
YMR145C |
Mitochondrial external NADH dehydrogenase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ATG33 |
YLR356W |
Mitochondrial mitophagy-specific protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| OM14 |
YBR230C |
Mitochondrial outer membrane receptor for cytosolic ribosomes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PRX1 |
YBL064C |
Mitochondrial peroxiredoxin with thioredoxin peroxidase activity |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| VPS73 |
YGL104C |
Mitochondrial protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| NNR1 |
YNL200C |
NADHX epimerase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RCH1 |
YMR034C |
Negative regulator of cytosolic calcium homeostasis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HSP30 |
YCR021C |
Negative regulator of the H(+)-ATPase Pma1p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| NPT1 |
YOR209C |
Nicotinate phosphoribosyltransferase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HAM1 |
YJR069C |
Nucleoside triphosphate pyrophosphohydrolase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PHO11 |
YAR071W |
One of three repressible acid phosphatases |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PHO12 |
YHR215W |
One of three repressible acid phosphatases |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ARG3 |
YJL088W |
Ornithine carbamoyltransferase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ZEO1 |
YOL109W |
Peripheral membrane protein of the plasma membrane |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PXP1 |
YEL020C |
Peroxisomal matrix protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PRM5 |
YIL117C |
Pheromone-regulated protein, predicted to have 1 transmembrane segment |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CHO1 |
YER026C |
Phosphatidylserine synthase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GPX2 |
YBR244W |
Phospholipid hydroperoxide glutathione peroxidase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PHO89 |
YBR296C |
Plasma membrane Na+/Pi cotransporter |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YDR034W-B |
YDR034W-B |
Predicted tail-anchored plasma membrane protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPS5 |
YJR123W |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPS4A |
YJR145C |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SDS24 |
YBR214W |
Protein involved in cell separation during budding |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SIM1 |
YIL123W |
Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SNO1 |
YMR095C |
Protein of unconfirmed function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| BSC1 |
YDL037C |
Protein of unconfirmed function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TVS1 |
YCR061W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| DIA1 |
YMR316W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| INA1 |
YLR413W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HER1 |
YOR227W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YHR138C |
YHR138C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CSS3 |
YOL159C |
Protein of unknown function, secreted when constitutively expressed |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SPG5 |
YMR191W |
Protein required for proteasome assembly during quiescence |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YER152C |
YER152C |
Protein with 2-aminoadipate transaminase activity |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| UTR4 |
YEL038W |
Protein with sequence similarity to acireductone synthases |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YSP3 |
YOR003W |
Putative precursor of the subtilisin-like protease III |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YER079W |
YER079W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YDR209C |
YDR209C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YCL042W |
YCL042W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YNL115C |
YNL115C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YOR385W |
YOR385W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YNL146W |
YNL146W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YOL014W |
YOL014W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YDL241W |
YDL241W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PYC1 |
YGL062W |
Pyruvate carboxylase isoform |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC19 |
YAL038W |
Pyruvate kinase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| BNA6 |
YFR047C |
Quinolinate phosphoribosyl transferase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GSP1 |
YLR293C |
Ran GTPase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| STE2 |
YFL026W |
Receptor for alpha-factor pheromone |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPL13A |
YDL082W |
Ribosomal 60S subunit protein L13A |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPL17A |
YKL180W |
Ribosomal 60S subunit protein L17A |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPL21A |
YBR191W |
Ribosomal 60S subunit protein L21A |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPL32 |
YBL092W |
Ribosomal 60S subunit protein L32 |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| EFM5 |
YGR001C |
S-adenosylmethionine-dependent lysine methyltransferase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SPE3 |
YPR069C |
Spermidine synthase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GID11 |
YLR149C |
Substrate receptor of the glucose-induced degradation-deficient (GID) |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| EGD1 |
YPL037C |
Subunit beta1 of the nascent polypeptide-associated complex (NAC) |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ATP20 |
YPR020W |
Subunit g of the mitochondrial F1F0 ATP synthase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GPA1 |
YHR005C |
Subunit of G protein involved in pheromone response |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| UGA2 |
YBR006W |
Succinate semialdehyde dehydrogenase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SOA1 |
YIL166C |
Sulfonate and inorganic sulfur transporter |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MIG3 |
YER028C |
Transcriptional regulator |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| EFB1 |
YAL003W |
Translation elongation factor 1 beta |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YEF3 |
YLR249W |
Translation elongation factor 3 |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TIF2 |
YJL138C |
Translation initiation factor eIF4A |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GCV1 |
YDR019C |
T subunit of the mitochondrial glycine decarboxylase complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| UBC8 |
YEL012W |
Ubiquitin-conjugating enzyme that regulates gluconeogenesis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FUR1 |
YHR128W |
Uracil phosphoribosyltransferase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| APE1 |
YKL103C |
Vacuolar aminopeptidase yscI |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| AVT6 |
YER119C |
Vacuolar aspartate and glutamate exporter |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ATG22 |
YCL038C |
Vacuolar integral membrane protein required for efflux of amino acids |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TAG1 |
YLR173W |
Vacuolar membrane protein involved in termination of autophagy |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ATG42 |
YBR139W |
Vacuolar serine-type carboxypeptidase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CEF1 |
YMR213W |
Essential splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSA1 |
YGL111W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL38 |
YLR325C |
Ribosomal 60S subunit protein L38 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP9 |
YJL010C |
Essential subunit of U3-containing 90S preribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP123 |
YER110C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUC1 |
YJL208C |
Major mitochondrial nuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AMN1 |
YBR158W |
Modulator of cell separation and mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP1 |
YNL221C |
Subunit of RNase MRP, nuclear RNase P and telomerase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LTO1 |
YNL260C |
Substrate-specific adaptor protein involved in apo-Rli1p maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC42 |
YLR229C |
Small rho-like GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MES1 |
YGR264C |
Methionyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAP185 |
YJL098W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPO31 |
YOR116C |
RNA polymerase III largest subunit C160 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MFT1 |
YML062C |
Subunit of the THO complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD2 |
YGR083C |
Delta subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPE1 |
YKL059C |
Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT10 |
YPL183C |
WD40 domain-containing protein involved in endosomal recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AOS1 |
YPR180W |
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC2 |
YLR127C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APL2 |
YKL135C |
Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BAT1 |
YHR208W |
Mitochondrial branched-chain amino acid (BCAA) aminotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AIM21 |
YIR003W |
Subunit of a complex that associates with actin filaments |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCA1 |
YER168C |
ATP (CTP):tRNA-specific tRNA nucleotidyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC45 |
YLR103C |
DNA replication initiation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| ENO1 |
YGR254W |
Enolase I, a phosphopyruvate hydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GDI1 |
YER136W |
GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAP2 |
YGL237C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HST1 |
YOL068C |
NAD(+)-dependent histone deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTB2 |
YBL002W |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HTB2 |
YBL002W |
Histone H2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KGD1 |
YIL125W |
Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM4 |
YER112W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MBP1 |
YDL056W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL10 |
YNL284C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL19 |
YNL185C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRP49 |
YKL167C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL35 |
YDR322W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRP10 |
YDL045W-A |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSH6 |
YDR097C |
Protein required for mismatch repair in mitosis and meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTR10 |
YOR160W |
Nuclear import receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG18 |
YFR021W |
Phosphoinositide binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POP2 |
YNR052C |
Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PRP31 |
YGR091W |
Splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP6 |
YBR055C |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIN1 |
YHR156C |
Non-essential component of U5 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NRD1 |
YNL251C |
RNA-binding subunit of Nrd1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NAB6 |
YML117W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTA2 |
YBL003C |
Histone H2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKT1 |
YNL085W |
Protein similar to nucleases that forms a complex with Pbp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| PTI1 |
YGR156W |
Essential component of CPF (cleavage and polyadenylation factor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC2 |
YJR068W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC5 |
YBR087W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FYV8 |
YGR196C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC53 |
YDL150W |
RNA polymerase III subunit C53 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRI1 |
YDL216C |
Catalytic subunit of the COP9 signalosome (CSN) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RET3 |
YPL010W |
Zeta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE1 |
YGL238W |
Nuclear envelope protein that acts as a recycling factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOS4 |
YIL112W |
Subunit of the Set3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABF2 |
YMR072W |
Mitochondrial DNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STB1 |
YNL309W |
Protein with role in regulation of MBF-specific transcription at Start |
physical |
1 |
1 |
1 |
Two-hybrid |
| STB2 |
YMR053C |
Protein that interacts with Sin3p in a two-hybrid assay |
physical |
1 |
1 |
1 |
Two-hybrid |
| STB3 |
YDR169C |
Ribosomal RNA processing element (RRPE)-binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| STB4 |
YMR019W |
Putative transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| STB5 |
YHR178W |
Transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STB6 |
YKL072W |
Protein that binds Sin3p in a two-hybrid assay |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNP1 |
YIL061C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Two-hybrid |
| YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| XBP1 |
YIL101C |
Transcriptional repressor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| XBP1 |
YIL101C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TGL3 |
YMR313C |
Bifunctional triacylglycerol lipase and LPE acyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| TVP23 |
YDR084C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR148C |
YPR148C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR338W |
YOR338W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UTP9 |
YHR196W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUF1 |
YOR187W |
Mitochondrial translation elongation factor Tu (EF-Tu) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP40 |
YKR092C |
Nucleolar serine-rich protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSM4 |
YIL030C |
Membrane-embedded ubiquitin-protein ligase and retrotranslocase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPR3 |
YGR059W |
Sporulation-specific homolog of the CDC3/10/11/12 family of genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TVS1 |
YCR061W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YGR122W |
YGR122W |
Protein that may be involved in pH regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP11 |
YKR098C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC7 |
YLR385C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRT1 |
YMR101C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRK2 |
YKR050W |
Component of the Trk1p-Trk2p potassium transport system |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| STD1 |
YOR047C |
Protein involved in control of glucose-regulated gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UPC2 |
YDR213W |
Sterol regulatory element binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR067C |
YGR067C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPP1 |
YPL138C |
Subunit of COMPASS (Set1C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TFC1 |
YBR123C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPC25 |
YER018C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UTP7 |
YER082C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YML018C |
YML018C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC1 |
YDR177W |
Ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP4 |
YDR324C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP6 |
YDR449C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFC4 |
YGR047C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VHT1 |
YGR065C |
High-affinity plasma membrane H+-biotin (vitamin H) symporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOM20 |
YGR082W |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLN1 |
YIL147C |
Transmembrane histidine phosphotransfer kinase and osmosensor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM54 |
YJL054W |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP18 |
YJL069C |
Small-subunit processome protein involved in pre-18S rRNA maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAE1 |
YJR067C |
Substrate-specific adaptor protein involved in apo-Rli1p maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD2 |
YKL018W |
Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFA1 |
YKL028W |
TFIIE large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBA1 |
YKL210W |
Ubiquitin activating enzyme (E1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF11 |
YMR260C |
Translation initiation factor eIF1A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOG2 |
YOR353C |
Key component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF3 |
YPL011C |
TFIID subunit (47 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC29 |
YPL124W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAH18 |
YPR048W |
Conserved NAPDH-dependent diflavin reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCM62 |
YBR044C |
Protein involved in assembly of the succinate dehydrogenase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TBS1 |
YBR150C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR298C-A |
YBR298C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR003W-A |
YDR003W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRP1 |
YDR007W |
Phosphoribosylanthranilate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTC5 |
YDR089W |
Novel subunit of the vacuolar transporter chaperone complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR248C |
YDR248C |
Putative gluconokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWM1 |
YDR260C |
Subunit of the anaphase-promoting complex (APC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSF2 |
YDR312W |
Protein required for ribosomal large subunit maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIP1 |
YDR422C |
One of three alternate beta-subunits of the Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER039C-A |
YER039C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VFA1 |
YER128W |
Protein that interacts with Vps4p and has a role in vacuolar sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP5 |
YER144C |
Putative ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WWM1 |
YFL010C |
WW domain containing protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YFH7 |
YFR007W |
Putative kinase with similarity to the PRK/URK/PANK kinase subfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOS8 |
YGL096W |
Homeodomain-containing protein and putative transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO74 |
YGL170C |
Component of the meiotic outer plaque of the spindle pole body |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL262W |
YGL262W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR035W-A |
YGR035W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNG1 |
YGR197C |
Protein involved in resistance to nitrosoguanidine and 6-azauracil |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCH1 |
YGR203W |
Phosphatase with sequence similarity to Mih1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO12 |
YHR152W |
Nucleolar protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR213W |
YHR213W |
Pseudogenic fragment with similarity to flocculins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLM1 |
YIL105C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL043W |
YJL043W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL107C |
YJL107C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOH1 |
YJL171C |
GPI-anchored cell wall protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMH11 |
YJR085C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM8 |
YJR135W-A |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCD2 |
YKL027W |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA5 |
YKL080W |
Subunit C of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKL106C-A |
YKL106C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLL032C |
YLL032C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR036C |
YLR036C |
Putative protein predicted to have transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| YLR412C-A |
YLR412C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR419W |
YLR419W |
Putative helicase with limited sequence similarity to human Rb protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML053C |
YML053C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SML1 |
YML058W |
Ribonucleotide reductase inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML108W |
YML108W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNO1 |
YMR095C |
Protein of unconfirmed function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR175W-A |
YMR175W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR295C |
YMR295C |
Protein of unknown function that associates with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL042W-B |
YNL042W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOM7 |
YNL070W |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL165W |
YNL165W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLZ1 |
YNL196C |
Sporulation-specific protein with a leucine zipper motif |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTP1 |
YNL237W |
Probable type-III integral membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WSC2 |
YNL283C |
Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNZ2 |
YNL333W |
Protein involved in thiamine and pyridoxine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR065C |
YNR065C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLL058W |
YLL058W |
Putative protein of unknown function with similarity to Str2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL140C |
YNL140C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM13 |
YOL125W |
2'-O-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPS4 |
YOR313C |
Protein whose expression is induced during sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR365C |
YOR365C |
Putative protein involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRL4 |
YPL033C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL077C |
YPL077C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR114W |
YPR114W |
Protein distantly similar to ceramide synthases, Lag1p and Lac1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR172W |
YPR172W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URA1 |
YKL216W |
Dihydroorotate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIM1 |
YMR152W |
Aldehyde reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
| URA5 |
YML106W |
Major orotate phosphoribosyltransferase (OPRTase) isozyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YDL114W |
YDL114W |
Putative short-chain dehydrogenase/reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT1 |
YFL038C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YIA6 |
YIL006W |
Mitochondrial NAD+ transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YND1 |
YER005W |
Apyrase with wide substrate specificity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC14 |
YLR386W |
Enzyme regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UGA1 |
YGR019W |
Gamma-aminobutyrate (GABA) transaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKM1 |
YOL113W |
Member of the PAK family of serine/threonine protein kinases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR096W |
YJR096W |
Xylose and arabinose reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YVH1 |
YIR026C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMC1 |
YPR058W |
Secondary mitochondrial inner membrane glycine transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USV1 |
YPL230W |
Putative transcription factor containing a C2H2 zinc finger |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT32 |
YGL210W |
Rab family GTPase involved in the exocytic pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TDA5 |
YLR426W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO23 |
YBR250W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR174W-A |
YGR174W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TDA1 |
YMR291W |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPC1 |
YBR183W |
Alkaline ceramidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSB3 |
YFR024C-A |
Protein containing a C-terminal SH3 domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAK1 |
YER129W |
Upstream serine/threonine kinase for the SNF1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EFB1 |
YAL003W |
Translation elongation factor 1 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GLN1 |
YPR035W |
Glutamine synthetase (GS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUN30 |
YAL019W |
Snf2p family member with ATP-dependent chromatin remodeling activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BDH2 |
YAL061W |
Putative medium-chain alcohol dehydrogenase with similarity to BDH1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSM7 |
YJR113C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HEL2 |
YDR266C |
RING finger ubiquitin ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ADO1 |
YJR105W |
Adenosine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG29 |
YPL166W |
Autophagy-specific protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTK1 |
YDL025C |
Putative protein kinase, potentially phosphorylated by Cdc28p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTB1 |
YDR224C |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CNB1 |
YKL190W |
Calcineurin B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARO4 |
YBR249C |
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV5 |
YLR355C |
Acetohydroxyacid reductoisomerase and mtDNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KOG1 |
YHR186C |
Subunit of TORC1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DIG2 |
YDR480W |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAT2 |
YLR027C |
Cytosolic aspartate aminotransferase involved in nitrogen metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP10 |
YDR106W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM30 |
YLR368W |
F-box component of an SCF ubiquitin protein ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYC8 |
YBR112C |
General transcriptional co-repressor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INM1 |
YHR046C |
Inositol monophosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBK1 |
YNL161W |
Serine/threonine protein kinase of the the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DYN2 |
YDR424C |
Cytoplasmic light chain dynein, microtubule motor protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| ELA1 |
YNL230C |
Elongin A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MLH3 |
YPL164C |
Protein involved in DNA mismatch repair and meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOP1 |
YDR141C |
Protein involved in vesicular transport at trans-Golgi network (TGN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUG2 |
YBR281C |
Component of glutamine amidotransferase (GATase II) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDB1 |
YPR184W |
Glycogen debranching enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| IMD4 |
YML056C |
Inosine monophosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LTP1 |
YPR073C |
Protein phosphotyrosine phosphatase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PBA1 |
YLR199C |
Protein involved in 20S proteasome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADD66 |
YKL206C |
Protein involved in 20S proteasome assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD24 |
YER173W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPE1 |
YHR075C |
Protein with carboxyl methyl esterase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC21 |
YDR482C |
Protein involved in RNA splicing by the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE17 |
YMR120C |
Enzyme of 'de novo' purine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEK1 |
YOR351C |
Meiosis-specific serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKK2 |
YPL140C |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCK2 |
YER167W |
Serine/threonine-rich protein involved in PKC1 signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| RAD14 |
YMR201C |
Subunit of Nucleotide Excision Repair Factor 1 (NEF1) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FPK1 |
YNR047W |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICP55 |
YER078C |
Mitochondrial aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC4 |
YFL005W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AHC1 |
YOR023C |
Subunit of the Ada histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP53 |
YPL146C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RMT2 |
YDR465C |
Arginine N5 methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MAS2 |
YHR024C |
Alpha subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUB1 |
YCR076C |
Proteasome-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUT1 |
YBR252W |
Deoxyuridine triphosphate diphosphatase (dUTPase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CPR3 |
YML078W |
Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEF1 |
YBL066C |
Putative transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSC1 |
YLR241W |
Calcium permeable gated cation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD26 |
YJR035W |
Protein involved in transcription-coupled nucleotide excision repair |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MEC3 |
YLR288C |
DNA damage and meiotic pachytene checkpoint protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIM11 |
YMR139W |
Protein kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTA1 |
YJR062C |
Amidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSO2 |
YMR137C |
Nuclease required for DNA single- and double-strand break repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARO9 |
YHR137W |
Aromatic aminotransferase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AFG3 |
YER017C |
Mitochondrial inner membrane m-AAA protease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADH5 |
YBR145W |
Alcohol dehydrogenase isoenzyme V |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUE5 |
YOR042W |
Ubiquitin-binding protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC43 |
YGL155W |
Beta subunit of geranylgeranyltransferase type I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPR2 |
YHR057C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO2 |
YDR123C |
Transcription factor |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| NDL1 |
YLR254C |
Homolog of nuclear distribution factor NudE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLG1 |
YGL215W |
Cyclin-like protein that interacts with Pho85p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCL8 |
YPL219W |
Cyclin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IKS1 |
YJL057C |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACA1 |
YER045C |
ATF/CREB family basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IME1 |
YJR094C |
Master regulator of meiosis that is active only during meiotic events |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG27 |
YJL178C |
Type I membrane protein involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMD1 |
YDL001W |
Cytoplasmic protein required for sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QCR6 |
YFR033C |
Subunit 6 of the ubiquinol cytochrome-c reductase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RUB1 |
YDR139C |
Ubiquitin-like protein with similarity to mammalian NEDD8 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ART5 |
YGR068C |
Protein proposed to regulate endocytosis of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHU1 |
YHL006C |
Component of Shu complex (aka PCSS complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DSE3 |
YOR264W |
Daughter cell-specific protein, may help establish daughter fate |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NHP6A |
YPR052C |
High-mobility group (HMG) protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| JIP5 |
YPR169W |
Protein required for biogenesis of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP1 |
YHR062C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL20B |
YOR312C |
Ribosomal 60S subunit protein L20B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIF2 |
YKL089W |
Centromeric CDEIII region binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| RIF1 |
YBR275C |
Protein involved in control of DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRQ1 |
YDR373W |
N-myristoylated calcium-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATS1 |
YAL020C |
Protein required for modification of wobble nucleosides in tRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRK1 |
YIL095W |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC6 |
YIL068C |
Essential 88kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MPS2 |
YGL075C |
Essential membrane protein localized at nuclear envelope and SPBs |
physical |
1 |
1 |
1 |
Two-hybrid |
| DPH2 |
YKL191W |
Protein required for synthesis of diphthamide |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IQG1 |
YPL242C |
Actin filament binding protein that enhances actin ring formation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO2 |
YDL106C |
Homeobox transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SFI1 |
YLL003W |
Centrin (Cdc31p)-binding protein required for SPB duplication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAL4 |
YPL248C |
DNA-binding transcription factor required for activating GAL genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMP46 |
YLR080W |
Integral membrane component of ER-derived COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAP4 |
YKL109W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PRM8 |
YGL053W |
Pheromone-regulated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BAG7 |
YOR134W |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERV46 |
YAL042W |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| GAP1 |
YKR039W |
General amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SGM1 |
YJR134C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAL80 |
YML051W |
Transcriptional regulator involved in the repression of GAL genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNR1 |
YIL159W |
Formin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RBL2 |
YOR265W |
Protein involved in microtubule morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD6 |
YLR319C |
Actin- and formin-interacting protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESC1 |
YMR219W |
Protein involved in telomeric silencing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET32 |
YDR253C |
Zinc-finger DNA-binding transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MID2 |
YLR332W |
O-glycosylated plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET309 |
YLR067C |
Specific translational activator for the COX1 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCD5 |
YOR329C |
Protein required for normal actin organization and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIX17 |
YMR002W |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ALG5 |
YPL227C |
UDP-glucose:dolichyl-phosphate glucosyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HO |
YDL227C |
Site-specific endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHT2 |
YNL031C |
Histone H3 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RDI1 |
YDL135C |
Rho GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERV29 |
YGR284C |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BSD2 |
YBR290W |
Heavy metal ion homeostasis protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBI2 |
YNL015W |
Cytosolic inhibitor of vacuolar proteinase B (PRB1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN14 |
YJR061W |
Protein required for N-glycan mannosylphosphorylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DYS1 |
YHR068W |
Deoxyhypusine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLB3 |
YDL155W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTN1 |
YDR233C |
Reticulon protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| EUC1 |
YMR111C |
Sequence-specific DNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PXA2 |
YKL188C |
Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p |
physical |
1 |
1 |
1 |
PCA |
| ECM21 |
YBL101C |
Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EPO1 |
YMR124W |
Protein involved in septin-ER tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUG1 |
YDL099W |
Cis-golgi localized protein involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GTA1 |
YEL043W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CNN1 |
YFR046C |
Kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLR1 |
YPL091W |
Cytosolic and mitochondrial glutathione oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PLP1 |
YDR183W |
Protein that interacts with CCT (chaperonin containing TCP-1) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIT1 |
YNR001C |
Mitochondrial citrate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIH1 |
YHR034C |
Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASF2 |
YDL197C |
Anti-silencing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IFH1 |
YLR223C |
Coactivator, regulates transcription of ribosomal protein (RP) genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KTR2 |
YKR061W |
Mannosyltransferase involved in N-linked protein glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC8 |
YPR055W |
Essential 121 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EXP1 |
YDL121C |
A cargo receptor protein for Pma1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NGR1 |
YBR212W |
RNA binding protein that negatively regulates growth rate |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MBA1 |
YBR185C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAT4 |
YCR008W |
Ser/Thr protein kinase involved in salt tolerance, nutrient response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTH1 |
YDR001C |
Neutral trehalase, degrades trehalose |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EKI1 |
YDR147W |
Ethanolamine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FCF2 |
YLR051C |
Nucleolar protein involved in the early steps of 35S rRNA processing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISD11 |
YER048W-A |
Cysteine desulfurase (Nfs1p) activator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUE3 |
YGL110C |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEL1 |
YHR035W |
Activator of Sar1p GTPase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MVB12 |
YGR206W |
ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PDR10 |
YOR328W |
ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTP1 |
YBR291C |
Mitochondrial inner membrane citrate transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LOT6 |
YLR011W |
FMN-dependent NAD(P)H:quinone reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RNH201 |
YNL072W |
Ribonuclease H2 catalytic subunit |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| NAM2 |
YLR382C |
Mitochondrial leucyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GTT3 |
YEL017W |
Protein of unknown function may be involved in glutathione metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSF1 |
YPR047W |
Mitochondrial phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OGG1 |
YML060W |
Nuclear and mitochondrial glycosylase/lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RTR1 |
YER139C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS21A |
YKR057W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIL1 |
YFL034W |
Predicted lipase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NHA1 |
YLR138W |
Na+/H+ antiporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEM1 |
YDR232W |
5-aminolevulinate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL26B |
YGR034W |
Ribosomal 60S subunit protein L26B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AGE2 |
YIL044C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DLD2 |
YDL178W |
D-2-hydroxyglutarate dehydrogenase, and minor D-lactate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP54 |
YOL065C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| PHO91 |
YNR013C |
Low-affinity vacuolar phosphate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NMT1 |
YLR195C |
N-myristoyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DGR2 |
YKL121W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAG1 |
YHL003C |
Ceramide synthase component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM22 |
YLR228C |
Sterol regulatory element binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX3 |
YBL095W |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGM1 |
YMR182C |
Putative zinc finger DNA binding transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM7 |
YLR443W |
Putative integral membrane protein with a role in calcium uptake |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PNT1 |
YOR266W |
Mitochondrial integral inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAD4 |
YDL243C |
Putative aryl-alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWH43 |
YCR017C |
GPI lipid remodelase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKH3 |
YDR466W |
Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGO1 |
YOR073W |
Component of the spindle checkpoint |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL15B |
YMR121C |
Ribosomal 60S subunit protein L15B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EST2 |
YLR318W |
Reverse transcriptase subunit of the telomerase holoenzyme |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| ASI1 |
YMR119W |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTA1 |
YDR256C |
Catalase A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSF1 |
YMR030W |
Protein required for respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PNP1 |
YLR209C |
Purine nucleoside phosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAR1 |
YMR171C |
Specificity factor required for Rsp5p-dependent ubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BXI1 |
YNL305C |
Protein involved in apoptosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTR2 |
YKR093W |
Integral membrane peptide transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM34 |
YMR003W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMC1 |
YGL006W |
Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRX6 |
YNL295W |
Mitochondrial ribosome-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALG12 |
YNR030W |
Alpha-1,6-mannosyltransferase localized to the ER |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| HUG1 |
YML058W-A |
Ribonucleotide reductase inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OAC1 |
YKL120W |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AMD2 |
YDR242W |
Putative amidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPE1 |
YJL121C |
D-ribulose-5-phosphate 3-epimerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAM2 |
YKL019W |
Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MTC2 |
YKL098W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| GRX2 |
YDR513W |
Cytoplasmic glutaredoxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EDC1 |
YGL222C |
RNA-binding protein that activates mRNA decapping directly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAT1 |
YML113W |
DNA binding protein that recognizes oligo(dA).oligo(dT) tracts |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAN4 |
YJR151C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FLO1 |
YAR050W |
Lectin-like protein involved in flocculation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI18 |
YBR004C |
Functional ortholog of human PIG-V |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FCY22 |
YER060W-A |
Putative purine-cytosine permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG41 |
YPL250C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX4 |
YGR133W |
Peroxisomal ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLB6 |
YGR109C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMD8 |
YFR048W |
Cytosolic protein required for sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUG3 |
YNL191W |
Component of glutamine amidotransferase (GATase II) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SED4 |
YCR067C |
Integral ER membrane protein that stimulates Sar1p GTPase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MUP3 |
YHL036W |
Low affinity methionine permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSB1 |
YOR049C |
Sphingoid long-chain base (LCB) efflux transporter |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RCE1 |
YMR274C |
Type II CAAX prenyl protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIR1 |
YKL164C |
O-glycosylated protein required for cell wall stability |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS25A |
YGR027C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EFM5 |
YGR001C |
S-adenosylmethionine-dependent lysine methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX14 |
YDR115W |
Putative mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMC1 |
YIL098C |
Mitochondrial matrix protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSC2 |
YGR244C |
Beta subunit of succinyl-CoA ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM4 |
YKR076W |
S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HPF1 |
YOL155C |
Haze-protective mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MZM1 |
YDR493W |
Protein required for assembly of the cytochrome bc(1) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDL2 |
YPL270W |
Mitochondrial inner membrane half-type ABC transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AGC1 |
YPR021C |
Mitochondrial amino acid transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BER1 |
YLR412W |
Protein involved in microtubule-related processes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAT3 |
YLR013W |
Protein containing GATA family zinc finger motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEE1 |
YPL054W |
Zinc-finger protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG11 |
YNL048W |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROT2 |
YBR229C |
Glucosidase II catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CNE1 |
YAL058W |
Calnexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKP1 |
YIL042C |
Mitochondrial protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPN2 |
YNL217W |
Zn2+-dependent endopolyphosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ENV9 |
YOR246C |
Conserved oxidoreductase involved in lipid droplet morphology |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BCD1 |
YHR040W |
Essential protein required for the accumulation of box C/D snoRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FSH1 |
YHR049W |
Lysophospholipase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM33 |
YML087C |
Protein of unknown function, highly conserved across species |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NCA2 |
YPR155C |
Protein that regulates expression of Fo-F1 ATP synthase subunits |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RCF1 |
YML030W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFA1 |
YDL168W |
Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BNA4 |
YBL098W |
Kynurenine 3-monooxygenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUT2 |
YHR037W |
Delta-1-pyrroline-5-carboxylate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IAH1 |
YOR126C |
Isoamyl acetate-hydrolyzing esterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCT1 |
YKL134C |
Mitochondrial intermediate peptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIF1 |
YNR074C |
Mitochondrial cell death effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRX10 |
YDR282C |
Mitochondrial inner membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX8 |
YDR336W |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRC21 |
YMR073C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSC6 |
YOR354C |
Multicopy suppressor of HER2 involved in mitochondrial translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIT2 |
YJL126W |
Nit protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHM6 |
YDR281C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRX11 |
YPL041C |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RME1 |
YGR044C |
Zinc finger protein involved in control of meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NPP1 |
YCR026C |
Nucleotide pyrophosphatase/phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUS2 |
YGL063W |
Mitochondrial tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCH1 |
YMR034C |
Negative regulator of cytosolic calcium homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAU16 |
YKL224C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |