Standard name Systematic name Name description Description
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant
Visualize the interactome of CDC28
Links to external databases:
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Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 30

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.555 0.493 0.562
Nucleus 0.120 0.180 0.189
Vac/Vac Memb 0.378 0.361 0.346

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 6670

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CDC28 21 18 1 1 4

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 28 5 26 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification, Affinity Capture-Western, Co-purification, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Biochemical Activity, Reconstituted Complex, Reconstituted Complex
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle physical 26 4 24 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) physical 22 5 21 Reconstituted Complex, Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, Affinity Capture-MS, Protein-peptide, Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor physical 20 6 16 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Biochemical Activity, Affinity Capture-Western, Affinity Capture-MS
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase physical 17 4 17 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-localization, Reconstituted Complex
CLB3 YDL155W B-type cyclin involved in cell cycle progression physical 16 5 16 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 15 3 9 Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Biochemical Activity, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity
FAR1 YJL157C CDK inhibitor and nuclear anchor physical 14 5 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, PCA, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
CDC6 YJL194W Essential ATP-binding protein required for DNA replication physical 13 3 11 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
CLN3 YAL040C G1 cyclin involved in cell cycle progression physical 11 4 10 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Two-hybrid, Affinity Capture-MS, Biochemical Activity, Biochemical Activity, Affinity Capture-Western, Biochemical Activity
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 10 6 9 Dosage Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Lethality, Synthetic Growth Defect, Synthetic Rescue, Negative Genetic
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle physical 9 4 9 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Biochemical Activity
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) physical 9 3 9 Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Biochemical Activity
CAK1 YFL029C Cyclin-dependent kinase-activating kinase physical 9 5 7 Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Two-hybrid, Two-hybrid, Affinity Capture-MS
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 9 4 4 Dosage Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Phenotypic Enhancement, Negative Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 8 3 7 Dosage Rescue, Synthetic Rescue, Synthetic Rescue, Dosage Rescue, Dosage Rescue, Synthetic Rescue, Dosage Lethality, Dosage Rescue
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation physical 8 2 7 Protein-peptide, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 7 3 7 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Phenotypic Enhancement
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start physical 7 2 7 Biochemical Activity, Biochemical Activity, PCA, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
WHI5 YOR083W Repressor of G1 transcription physical 7 1 7 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 7 5 6 Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression, Dosage Lethality, Dosage Rescue
ORC6 YHR118C Subunit of the origin recognition complex (ORC) physical 6 1 6 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
FIN1 YDR130C Spindle pole body-related intermediate filament protein physical 6 1 6 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
SLT2 YHR030C Serine/threonine MAP kinase genetic 6 4 5 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Positive Genetic, Positive Genetic, Dosage Lethality
HSL1 YKL101W Nim1p-related protein kinase genetic 6 3 5 Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 6 2 5 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
ELM1 YKL048C Serine/threonine protein kinase genetic 6 3 4 Synthetic Lethality, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 5 4 5 Dosage Rescue, Synthetic Rescue, Dosage Growth Defect, Dosage Rescue, Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 5 4 5 Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression, Positive Genetic, Dosage Lethality
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes physical 5 3 5 Two-hybrid, PCA, Biochemical Activity, Biochemical Activity, Biochemical Activity
SWI6 YLR182W Transcription cofactor physical 5 2 5 Biochemical Activity, PCA, Biochemical Activity, PCA, Biochemical Activity
NDD1 YOR372C Transcriptional activator essential for nuclear division physical 5 1 5 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex physical 5 1 5 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 5 4 4 Dosage Lethality, Synthetic Lethality, Dosage Rescue, Negative Genetic, Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 5 4 4 Synthetic Lethality, Synthetic Rescue, Negative Genetic, Negative Genetic, Dosage Lethality
PDS1 YDR113C Securin physical 5 2 4 Reconstituted Complex, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 5 4 3 Dosage Rescue, Synthetic Lethality, Negative Genetic, Negative Genetic, Dosage Lethality
SRL3 YKR091W Repressor of transcription at Start physical 5 4 3 Biochemical Activity, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Biochemical Activity
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 5 3 3 Negative Genetic, Synthetic Growth Defect, Positive Genetic, Negative Genetic, Negative Genetic
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 4 4 4 Two-hybrid, Co-localization, Affinity Capture-Western, Biochemical Activity
CLB4 YLR210W B-type cyclin involved in cell cycle progression physical 4 3 4 Reconstituted Complex, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS
MSA1 YOR066W Activator of G1-specific transcription factors MBF and SBF physical 4 3 4 Two-hybrid, Biochemical Activity, Affinity Capture-MS, Biochemical Activity
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 4 3 4 Phenotypic Enhancement, Synthetic Growth Defect, Dosage Lethality, Dosage Lethality
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 4 2 4 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Dosage Rescue
MCM3 YEL032W Protein involved in DNA replication physical 4 2 4 Biochemical Activity, PCA, Biochemical Activity, Biochemical Activity
NET1 YJL076W Core subunit of the RENT complex physical 4 2 4 PCA, Biochemical Activity, Biochemical Activity, Biochemical Activity
SPC110 YDR356W Inner plaque spindle pole body (SPB) component physical 4 1 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
ORC2 YBR060C Subunit of the origin recognition complex (ORC) physical 4 1 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
CNN1 YFR046C Kinetochore protein physical 4 1 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
SLD2 YKL108W Single-stranded DNA origin-binding and annealing protein physical 4 1 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly physical 4 1 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
FIR1 YER032W Protein involved in 3' mRNA processing physical 4 1 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
YOX1 YML027W Homeobox transcriptional repressor physical 4 1 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis physical 4 1 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails physical 4 1 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
KAR9 YPL269W Spindle positioning factor physical 4 3 3 Two-hybrid, Biochemical Activity, Biochemical Activity, PCA
WHI5 YOR083W Repressor of G1 transcription genetic 4 3 3 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Phenotypic Enhancement
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 4 3 3 Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 4 3 3 Phenotypic Enhancement, Synthetic Lethality, Negative Genetic, Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 4 3 3 Dosage Growth Defect, Negative Genetic, Negative Genetic, Dosage Lethality
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 4 2 3 Negative Genetic, Phenotypic Suppression, Negative Genetic, Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 4 2 3 Negative Genetic, Negative Genetic, Negative Genetic, Dosage Lethality
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 4 2 3 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 4 3 2 Positive Genetic, Negative Genetic, Negative Genetic, Dosage Lethality
CLB3 YDL155W B-type cyclin involved in cell cycle progression genetic 3 3 3 Dosage Rescue, Phenotypic Enhancement, Synthetic Growth Defect
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring physical 3 3 3 Affinity Capture-Western, PCA, Biochemical Activity
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) physical 3 3 3 Affinity Capture-Western, Biochemical Activity, PCA
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 3 3 3 Synthetic Rescue, Phenotypic Suppression, Dosage Lethality
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 3 3 3 Synthetic Lethality, Negative Genetic, Dosage Lethality
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 3 3 3 Synthetic Rescue, Dosage Growth Defect, Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 3 3 3 Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 3 3 3 Phenotypic Enhancement, Phenotypic Suppression, Synthetic Rescue
NUM1 YDR150W Protein required for nuclear migration genetic 3 3 3 Synthetic Growth Defect, Negative Genetic, Dosage Lethality
BRE1 YDL074C E3 ubiquitin ligase genetic 3 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
CLB1 YGR108W B-type cyclin involved in cell cycle progression physical 3 2 3 Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
CLB1 YGR108W B-type cyclin involved in cell cycle progression genetic 3 2 3 Dosage Rescue, Dosage Rescue, Phenotypic Suppression
NDD1 YOR372C Transcriptional activator essential for nuclear division genetic 3 2 3 Dosage Rescue, Dosage Lethality, Dosage Lethality
LTE1 YAL024C Protein similar to GDP/GTP exchange factors physical 3 2 3 Biochemical Activity, PCA, Biochemical Activity
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase physical 3 2 3 PCA, Biochemical Activity, Biochemical Activity
ORC1 YML065W Largest subunit of the origin recognition complex physical 3 2 3 Affinity Capture-MS, Biochemical Activity, Biochemical Activity
SSD1 YDR293C Translational repressor genetic 3 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 3 2 3 Phenotypic Enhancement, Synthetic Rescue, Phenotypic Enhancement
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity
MPS1 YDL028C Dual-specificity kinase genetic 3 2 3 Dosage Lethality, Dosage Lethality, Negative Genetic
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis genetic 3 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Dosage Lethality
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
YEN1 YER041W Holliday junction resolvase physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
MIH1 YMR036C Protein tyrosine phosphatase physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
CIN8 YEL061C Bipolar kinesin motor protein physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
PLM2 YDR501W Putative transcription factor, contains Forkhead Associated domain physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
TOS4 YLR183C Putative transcription factor, contains Forkhead Associated domain physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
XBP1 YIL101C Transcriptional repressor physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
YHP1 YDR451C Homeobox transcriptional repressor physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
CSA1 YPR174C Protein of unknown function physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
HCM1 YCR065W Forkhead transcription factor physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
SMC4 YLR086W Subunit of the condensin complex physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
SFI1 YLL003W Centrin (Cdc31p)-binding protein required for SPB duplication physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
NTH1 YDR001C Neutral trehalase, degrades trehalose physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
RAD52 YML032C Protein involved in homologous recombination genetic 3 1 3 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BNI1 YNL271C Formin physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
BUD3 YCL014W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
ACM1 YPL267W Pseudosubstrate inhibitor of the APC/C physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
BOP3 YNL042W Protein of unknown function physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 3 3 2 Co-localization, Reconstituted Complex, Biochemical Activity
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start genetic 3 3 2 Dosage Lethality, Phenotypic Suppression, Phenotypic Enhancement
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 3 3 2 Phenotypic Enhancement, Negative Genetic, Positive Genetic
CIP1 YPL014W Cyclin-dependent kinase inhibitor physical 3 3 2 Biochemical Activity, Affinity Capture-Western, Reconstituted Complex
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 3 3 2 Synthetic Growth Defect, Positive Genetic, Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 3 2 2 Negative Genetic, Negative Genetic, Dosage Lethality
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor physical 3 2 2 Reconstituted Complex, Biochemical Activity, Biochemical Activity
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 3 2 2 Negative Genetic, Positive Genetic, Negative Genetic
LRE1 YCL051W Protein involved in control of cell wall structure and stress response physical 3 2 2 Biochemical Activity, Affinity Capture-Western, Biochemical Activity
SMC4 YLR086W Subunit of the condensin complex genetic 3 2 2 Positive Genetic, Positive Genetic, Dosage Lethality
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 3 2 2 Negative Genetic, Negative Genetic, Synthetic Growth Defect
STN1 YDR082W Telomere end-binding and capping protein genetic 3 2 2 Negative Genetic, Negative Genetic, Dosage Lethality
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 3 2 2 Negative Genetic, Negative Genetic, Dosage Lethality
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 3 2 2 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 3 2 2 Phenotypic Enhancement, Negative Genetic, Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 3 2 2 Dosage Rescue, Negative Genetic, Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 3 2 2 Positive Genetic, Positive Genetic, Dosage Lethality
SLU7 YDR088C RNA splicing factor genetic 3 2 2 Negative Genetic, Negative Genetic, Dosage Lethality
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 3 2 2 Negative Genetic, Negative Genetic, Dosage Lethality
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 3 2 2 Negative Genetic, Negative Genetic, Dosage Lethality
LSM1 YJL124C Lsm (Like Sm) protein genetic 3 2 2 Negative Genetic, Negative Genetic, Dosage Lethality
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 3 2 2 Negative Genetic, Positive Genetic, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 3 2 2 Phenotypic Enhancement, Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 3 2 2 Phenotypic Suppression, Positive Genetic, Positive Genetic
TOP1 YOL006C Topoisomerase I genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
YIH1 YCR059C Negative regulator of eIF2 kinase Gcn2p physical 3 3 1 Reconstituted Complex, Affinity Capture-Western, PCA
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 3 2 1 Affinity Capture-Western, Two-hybrid, Two-hybrid
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) regulation 2 2 2 qualitative western immunoblotting evidence, quantitative mass spectrometry evidence
NTH1 YDR001C Neutral trehalase, degrades trehalose regulation 2 2 2 protein kinase assay evidence, quantitative mass spectrometry evidence
MCM3 YEL032W Protein involved in DNA replication regulation 2 2 2 qualitative western immunoblotting evidence, quantitative mass spectrometry evidence
WHI5 YOR083W Repressor of G1 transcription regulation 2 2 2 qualitative western immunoblotting evidence, quantitative mass spectrometry evidence
SRL3 YKR091W Repressor of transcription at Start regulation 2 2 2 qualitative western immunoblotting evidence, quantitative mass spectrometry evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex genetic 2 2 2 Negative Genetic, Dosage Lethality
ASF1 YJL115W Nucleosome assembly factor physical 2 2 2 Biochemical Activity, PCA
ASF1 YJL115W Nucleosome assembly factor genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 2 2 2 Two-hybrid, Biochemical Activity
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 2 2 2 Synthetic Rescue, Negative Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 2 2 2 Positive Genetic, Dosage Lethality
MPT5 YGL178W mRNA-binding protein of the PUF family genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 2 2 2 Synthetic Lethality, Phenotypic Suppression
SPC42 YKL042W Central plaque component of spindle pole body (SPB) physical 2 2 2 Two-hybrid, Biochemical Activity
CLB4 YLR210W B-type cyclin involved in cell cycle progression genetic 2 2 2 Dosage Rescue, Phenotypic Enhancement
STE20 YHL007C Cdc42p-activated signal transducing kinase physical 2 2 2 Biochemical Activity, Affinity Capture-MS
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 2 2 2 Phenotypic Suppression, Negative Genetic
SKG3 YLR187W Protein of unknown function physical 2 2 2 Affinity Capture-MS, Biochemical Activity
CNM67 YNL225C Component of the spindle pole body outer plaque physical 2 2 2 Affinity Capture-Western, Biochemical Activity
SLT2 YHR030C Serine/threonine MAP kinase physical 2 2 2 Biochemical Activity, PCA
PCL7 YIL050W Pho85p cyclin of the Pho80p subfamily physical 2 2 2 Two-hybrid, Biochemical Activity
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex genetic 2 2 2 Synthetic Rescue, Dosage Lethality
ZDS2 YML109W Protein with a role in regulating Swe1p-dependent polarized growth genetic 2 2 2 Dosage Rescue, Synthetic Rescue
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 2 2 2 Dosage Growth Defect, Negative Genetic
MSA1 YOR066W Activator of G1-specific transcription factors MBF and SBF genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
SFG1 YOR315W Nuclear protein putative transcription factor physical 2 2 2 Two-hybrid, Biochemical Activity
KAR3 YPR141C Minus-end-directed microtubule motor physical 2 2 2 Two-hybrid, Biochemical Activity
YGR035C YGR035C Putative protein of unknown function, potential Cdc28p substrate physical 2 2 2 PCA, Biochemical Activity
NBP1 YLR457C Spindle pole body (SPB) component physical 2 2 2 PCA, Biochemical Activity
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation physical 2 2 2 PCA, Affinity Capture-MS
PTK2 YJR059W Serine/threonine protein kinase physical 2 2 2 PCA, Biochemical Activity
RAD9 YDR217C DNA damage-dependent checkpoint protein physical 2 2 2 PCA, Biochemical Activity
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p physical 2 2 2 PCA, Affinity Capture-MS
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase physical 2 2 2 Affinity Capture-MS, Biochemical Activity
KIN2 YLR096W S/T protein kinase physical 2 2 2 Affinity Capture-MS, Biochemical Activity
CIN8 YEL061C Bipolar kinesin motor protein genetic 2 2 2 Negative Genetic, Dosage Lethality
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 2 2 2 Biochemical Activity, Affinity Capture-MS
HHF1 YBR009C Histone H4 physical 2 2 2 Affinity Capture-Western, Biochemical Activity
RTT109 YLL002W Histone acetyltransferase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SPC29 YPL124W Inner plaque spindle pole body (SPB) component genetic 2 2 2 Negative Genetic, Dosage Lethality
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 2 2 2 Dosage Rescue, Synthetic Rescue
ELM1 YKL048C Serine/threonine protein kinase physical 2 2 2 PCA, Biochemical Activity
KIP2 YPL155C Kinesin-related motor protein involved in mitotic spindle positioning physical 2 2 2 PCA, Biochemical Activity
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase physical 2 2 2 PCA, Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
GRR1 YJR090C F-box protein component of an SCF ubiquitin-ligase complex physical 2 2 2 Biochemical Activity, Reconstituted Complex
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
UFE1 YOR075W t-SNARE protein required for retrograde vesicular traffic physical 2 2 2 Affinity Capture-MS, Biochemical Activity
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family physical 2 2 2 Affinity Capture-MS, Biochemical Activity
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) physical 2 2 2 Affinity Capture-MS, Biochemical Activity
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p physical 2 2 2 Affinity Capture-MS, Biochemical Activity
DNF2 YDR093W Aminophospholipid translocase (flippase) physical 2 2 2 Affinity Capture-MS, Biochemical Activity
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 2 2 2 Phenotypic Suppression, Dosage Lethality
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 2 2 2 Synthetic Rescue, Phenotypic Enhancement
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 2 2 2 Negative Genetic, Dosage Lethality
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex genetic 2 2 2 Phenotypic Enhancement, Dosage Lethality
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
SPO13 YHR014W Meiotic regulator genetic 2 2 2 Dosage Rescue, Phenotypic Enhancement
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 2 2 2 Synthetic Lethality, Dosage Lethality
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 2 2 2 Synthetic Lethality, Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 2 2 2 Synthetic Lethality, Negative Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
MSH2 YOL090W Protein that binds to DNA mismatches genetic 2 2 2 Phenotypic Enhancement, Dosage Lethality
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 2 2 2 Phenotypic Enhancement, Dosage Lethality
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 2 2 2 Phenotypic Enhancement, Dosage Lethality
RAD18 YCR066W E3 ubiquitin ligase genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 2 2 2 Phenotypic Enhancement, Dosage Lethality
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 2 2 2 Phenotypic Enhancement, Synthetic Rescue
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 2 2 2 Negative Genetic, Dosage Lethality
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 2 2 2 Synthetic Growth Defect, Dosage Rescue
MSN5 YDR335W Karyopherin genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
YSP2 YDR326C Sterol-binding protein genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
CHL1 YPL008W Probable DNA helicase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
VAC14 YLR386W Enzyme regulator genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RTR1 YER139C Dual specificity protein phosphatase genetic 2 2 2 Dosage Growth Defect, Negative Genetic
SGO1 YOR073W Component of the spindle checkpoint genetic 2 2 2 Synthetic Rescue, Dosage Lethality
LCD1 YDR499W Essential protein required for the DNA integrity checkpoint pathways genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
IGO1 YNL157W Protein required for initiation of G0 program genetic 2 2 2 Synthetic Rescue, Phenotypic Enhancement
IGO2 YHR132W-A Protein required for initiation of G0 program genetic 2 2 2 Synthetic Rescue, Phenotypic Enhancement
RMR1 YGL250W Protein required for meiotic recombination and gene conversion genetic 2 2 2 Positive Genetic, Dosage Lethality
SEG2 YKL105C Eisosome component genetic 2 2 2 Positive Genetic, Dosage Lethality
TFC3 YAL001C Subunit of RNA polymerase III transcription initiation factor complex genetic 2 2 2 Negative Genetic, Dosage Lethality
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 2 2 2 Negative Genetic, Dosage Lethality
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Dosage Lethality
TOA1 YOR194C TFIIA large subunit genetic 2 2 2 Negative Genetic, Dosage Lethality
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes genetic 2 2 2 Negative Genetic, Dosage Lethality
SYF1 YDR416W Member of the NineTeen Complex (NTC) genetic 2 2 2 Negative Genetic, Dosage Lethality
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 2 2 2 Negative Genetic, Dosage Lethality
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 2 2 2 Negative Genetic, Dosage Lethality
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family genetic 2 2 2 Negative Genetic, Dosage Lethality
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes genetic 2 2 2 Negative Genetic, Dosage Lethality
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 2 2 2 Negative Genetic, Dosage Lethality
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 2 2 2 Negative Genetic, Dosage Lethality
PRP40 YKL012W U1 snRNP protein involved in splicing genetic 2 2 2 Negative Genetic, Dosage Lethality
PRP16 YKR086W DEAH-box RNA helicase genetic 2 2 2 Negative Genetic, Dosage Lethality
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 2 2 2 Negative Genetic, Dosage Lethality
TOP2 YNL088W Topoisomerase II genetic 2 2 2 Negative Genetic, Dosage Lethality
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 2 2 2 Negative Genetic, Dosage Lethality
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 2 2 2 Negative Genetic, Dosage Lethality
MAP2 YBL091C Methionine aminopeptidase genetic 2 2 2 Negative Genetic, Dosage Lethality
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 2 2 2 Negative Genetic, Dosage Lethality
SWP82 YFL049W Member of the SWI/SNF chromatin remodeling complex genetic 2 2 2 Negative Genetic, Dosage Lethality
OSH7 YHR001W Oxysterol-binding phosphatidylserine transferase genetic 2 2 2 Negative Genetic, Dosage Lethality
SCH9 YHR205W AGC family protein kinase genetic 2 2 2 Negative Genetic, Dosage Lethality
EPO1 YMR124W Protein involved in septin-ER tethering genetic 2 2 2 Negative Genetic, Dosage Lethality
CDC16 YKL022C Subunit of the anaphase-promoting complex/cyclosome (APC/C) genetic 2 2 2 Synthetic Lethality, Phenotypic Suppression
BUR2 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
CCT7 YJL111W Subunit of the cytosolic chaperonin Cct ring complex physical 2 2 2 Biochemical Activity, PCA
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 2 2 2 Negative Genetic, Dosage Lethality
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 2 2 2 Dosage Rescue, Negative Genetic
ARP5 YNL059C Nuclear actin-related protein involved in chromatin remodeling genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
BUD6 YLR319C Actin- and formin-interacting protein physical 2 2 2 PCA, Biochemical Activity
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 2 2 2 Positive Genetic, Dosage Lethality
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 2 1 2 Dosage Rescue, Dosage Rescue
MET10 YFR030W Subunit alpha of assimilatory sulfite reductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DPB2 YPR175W Second largest subunit of DNA polymerase II (DNA polymerase epsilon) physical 2 1 2 Biochemical Activity, Biochemical Activity
DDC1 YPL194W DNA damage checkpoint protein physical 2 1 2 Biochemical Activity, Biochemical Activity
SSC1 YJR045C Hsp70 family ATPase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
KAR3 YPR141C Minus-end-directed microtubule motor genetic 2 1 2 Negative Genetic, Negative Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity physical 2 1 2 Biochemical Activity, Biochemical Activity
CHS2 YBR038W Chitin synthase II physical 2 1 2 Biochemical Activity, Biochemical Activity
MPC54 YOR177C Component of the meiotic outer plaque physical 2 1 2 Biochemical Activity, Biochemical Activity
FPK1 YNR047W Ser/Thr protein kinase physical 2 1 2 Biochemical Activity, Biochemical Activity
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function physical 2 1 2 Biochemical Activity, Biochemical Activity
YBR138C YBR138C Cytoplasmic protein of unknown function physical 2 1 2 Biochemical Activity, Biochemical Activity
KEL2 YGR238C Protein that negatively regulates mitotic exit physical 2 1 2 Biochemical Activity, Biochemical Activity
MOB1 YIL106W Component of the mitotic exit network physical 2 1 2 Biochemical Activity, Biochemical Activity
PXL1 YKR090W Protein that localizes to sites of polarized growth physical 2 1 2 Biochemical Activity, Biochemical Activity
YML119W YML119W Putative protein of unknown function physical 2 1 2 Biochemical Activity, Biochemical Activity
TOM6 YOR045W Component of the TOM (translocase of outer membrane) complex physical 2 1 2 Biochemical Activity, Biochemical Activity
IPL1 YPL209C Aurora kinase of chromosomal passenger complex physical 2 1 2 Biochemical Activity, Biochemical Activity
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex physical 2 1 2 Biochemical Activity, Biochemical Activity
STN1 YDR082W Telomere end-binding and capping protein physical 2 1 2 Biochemical Activity, Biochemical Activity
SAE2 YGL175C Endonuclease required for telomere elongation physical 2 1 2 Biochemical Activity, Biochemical Activity
HSP82 YPL240C Hsp90 chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 2 1 2 Negative Genetic, Negative Genetic
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) physical 2 1 2 Biochemical Activity, Biochemical Activity
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase physical 2 1 2 Biochemical Activity, Biochemical Activity
TGL5 YOR081C Bifunctional triacylglycerol lipase and LPA acyltransferase physical 2 1 2 Biochemical Activity, Biochemical Activity
YCL002C YCL002C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 1 2 Negative Genetic, Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 2 1 2 Negative Genetic, Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 2 1 2 Positive Genetic, Positive Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
DST1 YGL043W General transcription elongation factor TFIIS genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RPL11A YPR102C Ribosomal 60S subunit protein L11A genetic 2 1 2 Negative Genetic, Negative Genetic
COM2 YER130C Transcription factor that binds IME1 Upstream Activation Signal (UAS) genetic 2 1 2 Dosage Lethality, Dosage Lethality
MET4 YNL103W Leucine-zipper transcriptional activator genetic 2 1 2 Dosage Lethality, Dosage Lethality
CDC16 YKL022C Subunit of the anaphase-promoting complex/cyclosome (APC/C) physical 2 1 2 Biochemical Activity, Biochemical Activity
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 2 1 2 Biochemical Activity, Biochemical Activity
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
APC9 YLR102C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 2 1 2 Biochemical Activity, Biochemical Activity
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 2 1 2 Biochemical Activity, Biochemical Activity
BUD4 YJR092W Anillin-like protein involved in bud-site selection physical 2 1 2 Biochemical Activity, Biochemical Activity
BIK1 YCL029C Microtubule-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 2 1 2 Negative Genetic, Negative Genetic
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid physical 2 2 1 Affinity Capture-Western, Co-purification
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 2 2 1 Affinity Capture-Western, Co-purification
PHO2 YDL106C Homeobox transcription factor physical 2 2 1 Two-hybrid, Biochemical Activity
TUB4 YLR212C Gamma-tubulin physical 2 2 1 PCA, Biochemical Activity
INN1 YNL152W Essential protein that associates with contractile actomyosin ring physical 2 2 1 Affinity Capture-Western, Biochemical Activity
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 2 2 1 Positive Genetic, Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 2 2 1 Positive Genetic, Negative Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 2 2 1 Positive Genetic, Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 2 2 1 Positive Genetic, Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 2 2 1 Negative Genetic, Positive Genetic
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 2 1 1 Negative Genetic, Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 2 1 1 Negative Genetic, Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone physical 2 1 1 Two-hybrid, Two-hybrid
PHO2 YDL106C Homeobox transcription factor genetic 2 1 1 Negative Genetic, Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 2 1 1 Negative Genetic, Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 2 1 1 Negative Genetic, Negative Genetic
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase genetic 2 1 1 Negative Genetic, Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 2 1 1 Negative Genetic, Negative Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 2 1 1 Negative Genetic, Negative Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 2 1 1 Negative Genetic, Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 2 1 1 Positive Genetic, Positive Genetic
SEC62 YPL094C Essential subunit of Sec63 complex genetic 2 1 1 Positive Genetic, Positive Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 2 1 1 Positive Genetic, Positive Genetic
YRB1 YDR002W Ran GTPase binding protein genetic 2 1 1 Negative Genetic, Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 2 1 1 Negative Genetic, Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 1 1 Negative Genetic, Negative Genetic
SEC53 YFL045C Phosphomannomutase genetic 2 1 1 Negative Genetic, Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 2 1 1 Negative Genetic, Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 2 1 1 Negative Genetic, Negative Genetic
SKI6 YGR195W Exosome non-catalytic core component genetic 2 1 1 Negative Genetic, Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 2 1 1 Negative Genetic, Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 2 1 1 Negative Genetic, Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 2 1 1 Negative Genetic, Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 2 1 1 Negative Genetic, Negative Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 2 1 1 Negative Genetic, Negative Genetic
RPB8 YOR224C RNA polymerase subunit ABC14.5 genetic 2 1 1 Negative Genetic, Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 2 1 1 Negative Genetic, Negative Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 1 Negative Genetic, Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 2 1 1 Negative Genetic, Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 2 1 1 Negative Genetic, Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 2 1 1 Negative Genetic, Negative Genetic
CIA2 YHR122W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 2 1 1 Negative Genetic, Negative Genetic
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 2 1 1 Negative Genetic, Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 2 1 1 Negative Genetic, Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 2 1 1 Negative Genetic, Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
DBP6 YNR038W Essential protein involved in ribosome biogenesis genetic 2 1 1 Negative Genetic, Negative Genetic
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex genetic 2 1 1 Negative Genetic, Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 2 1 1 Negative Genetic, Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 2 1 1 Negative Genetic, Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 2 1 1 Negative Genetic, Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 2 1 1 Negative Genetic, Negative Genetic
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 2 1 1 Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 2 1 1 Negative Genetic, Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 2 1 1 Negative Genetic, Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 2 1 1 Negative Genetic, Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 2 1 1 Negative Genetic, Negative Genetic
URA4 YLR420W Dihydroorotase genetic 2 1 1 Negative Genetic, Negative Genetic
MSG5 YNL053W Dual-specificity protein phosphatase genetic 2 1 1 Negative Genetic, Negative Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 2 1 1 Negative Genetic, Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 2 1 1 Negative Genetic, Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 2 1 1 Negative Genetic, Negative Genetic
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase regulation 1 1 1 quantitative mass spectrometry evidence
BUD6 YLR319C Actin- and formin-interacting protein regulation 1 1 1 quantitative mass spectrometry evidence
YSC84 YHR016C Actin-binding protein regulation 1 1 1 quantitative mass spectrometry evidence
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton regulation 1 1 1 quantitative mass spectrometry evidence
IQG1 YPL242C Actin filament binding protein that enhances actin ring formation regulation 1 1 1 quantitative mass spectrometry evidence
MOB2 YFL034C-B Activator of Cbk1p kinase regulation 1 1 1 quantitative mass spectrometry evidence
BSP1 YPR171W Adapter that links synaptojanins to the cortical actin cytoskeleton regulation 1 1 1 quantitative mass spectrometry evidence
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis regulation 1 1 1 quantitative mass spectrometry evidence
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) regulation 1 1 1 quantitative mass spectrometry evidence
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome regulation 1 1 1 quantitative mass spectrometry evidence
ALY1 YKR021W Alpha arrestin, substrate of calcineurin regulation 1 1 1 quantitative mass spectrometry evidence
ECM21 YBL101C Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p regulation 1 1 1 quantitative mass spectrometry evidence
ALY2 YJL084C Alpha arrestin, Ub-ligase adaptor for Rsp5p regulation 1 1 1 quantitative mass spectrometry evidence
BUD4 YJR092W Anillin-like protein involved in bud-site selection regulation 1 1 1 quantitative mass spectrometry evidence
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs regulation 1 1 1 quantitative mass spectrometry evidence
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers regulation 1 1 1 quantitative mass spectrometry evidence
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase regulation 1 1 1 quantitative mass spectrometry evidence
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling regulation 1 1 1 quantitative mass spectrometry evidence
IPL1 YPL209C Aurora kinase of chromosomal passenger complex regulation 1 1 1 quantitative mass spectrometry evidence
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family regulation 1 1 1 quantitative mass spectrometry evidence
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase regulation 1 1 1 quantitative mass spectrometry evidence
CIN8 YEL061C Bipolar kinesin motor protein regulation 1 1 1 protein kinase assay evidence
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex regulation 1 1 1 quantitative mass spectrometry evidence
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) regulation 1 1 1 quantitative mass spectrometry evidence
VNX1 YNL321W Calcium/H+ antiporter localized to the endoplasmic reticulum membrane regulation 1 1 1 quantitative mass spectrometry evidence
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor regulation 1 1 1 quantitative mass spectrometry evidence
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex regulation 1 1 1 quantitative mass spectrometry evidence
STE20 YHL007C Cdc42p-activated signal transducing kinase regulation 1 1 1 quantitative mass spectrometry evidence
CLA4 YNL298W Cdc42p-activated signal transducing kinase regulation 1 1 1 quantitative mass spectrometry evidence
FAR1 YJL157C CDK inhibitor and nuclear anchor regulation 1 1 1 quantitative mass spectrometry evidence
SPC42 YKL042W Central plaque component of spindle pole body (SPB) regulation 1 1 1 quantitative mass spectrometry evidence
CHS2 YBR038W Chitin synthase II regulation 1 1 1 quantitative mass spectrometry evidence
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs regulation 1 1 1 quantitative mass spectrometry evidence
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport regulation 1 1 1 quantitative mass spectrometry evidence
SGT1 YOR057W Cochaperone protein regulation 1 1 1 quantitative mass spectrometry evidence
PEA2 YER149C Coiled-coil 12S polarisome subunit regulation 1 1 1 quantitative mass spectrometry evidence
GFD1 YMR255W Coiled-coiled protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins regulation 1 1 1 quantitative mass spectrometry evidence
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes regulation 1 1 1 quantitative mass spectrometry evidence
MSL5 YLR116W Component of commitment complex regulation 1 1 1 quantitative mass spectrometry evidence
SEG1 YMR086W Component of eisosome required for proper eisosome assembly regulation 1 1 1 quantitative mass spectrometry evidence
PBP1 YGR178C Component of glucose deprivation induced stress granules regulation 1 1 1 quantitative mass spectrometry evidence
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes regulation 1 1 1 quantitative mass spectrometry evidence
NOT5 YPR072W Component of the CCR4-NOT core complex, involved in mRNA decapping regulation 1 1 1 quantitative mass spectrometry evidence
LIF1 YGL090W Component of the DNA ligase IV complex regulation 1 1 1 quantitative mass spectrometry evidence
MOB1 YIL106W Component of the mitotic exit network regulation 1 1 1 quantitative mass spectrometry evidence
SPA2 YLL021W Component of the polarisome regulation 1 1 1 quantitative mass spectrometry evidence
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex regulation 1 1 1 quantitative mass spectrometry evidence
RSC2 YLR357W Component of the RSC chromatin remodeling complex regulation 1 1 1 quantitative mass spectrometry evidence
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat regulation 1 1 1 quantitative mass spectrometry evidence
SHS1 YDL225W Component of the septin ring that is required for cytokinesis regulation 1 1 1 quantitative mass spectrometry evidence
CDC3 YLR314C Component of the septin ring that is required for cytokinesis regulation 1 1 1 quantitative mass spectrometry evidence
CNM67 YNL225C Component of the spindle pole body outer plaque regulation 1 1 1 quantitative mass spectrometry evidence
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family regulation 1 1 1 quantitative mass spectrometry evidence
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding regulation 1 1 1 quantitative mass spectrometry evidence
NET1 YJL076W Core subunit of the RENT complex regulation 1 1 1 quantitative mass spectrometry evidence
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering regulation 1 1 1 quantitative mass spectrometry evidence
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator regulation 1 1 1 quantitative mass spectrometry evidence
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus regulation 1 1 1 quantitative mass spectrometry evidence
GIP4 YAL031C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p regulation 1 1 1 quantitative mass spectrometry evidence
SRO9 YCL037C Cytoplasmic RNA-binding protein regulation 1 1 1 quantitative mass spectrometry evidence
SLA1 YBL007C Cytoskeletal protein binding protein regulation 1 1 1 quantitative mass spectrometry evidence
CDC60 YPL160W Cytosolic leucyl tRNA synthetase regulation 1 1 1 quantitative mass spectrometry evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 1 1 1 quantitative mass spectrometry evidence
POG1 YIL122W DNA-binding transcriptional activator regulation 1 1 1 quantitative mass spectrometry evidence
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes regulation 1 1 1 quantitative mass spectrometry evidence
RAD9 YDR217C DNA damage-dependent checkpoint protein regulation 1 1 1 quantitative mass spectrometry evidence
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) regulation 1 1 1 quantitative mass spectrometry evidence
SEG2 YKL105C Eisosome component regulation 1 1 1 quantitative mass spectrometry evidence
ELA1 YNL230C Elongin A regulation 1 1 1 quantitative mass spectrometry evidence
ECM25 YJL201W Endocytic site protein required for stress-induced cell elongation regulation 1 1 1 quantitative mass spectrometry evidence
WSC4 YHL028W Endoplasmic reticulum (ER) membrane protein regulation 1 1 1 quantitative mass spectrometry evidence
ZRG17 YNR039C Endoplasmic reticulum zinc transporter regulation 1 1 1 quantitative mass spectrometry evidence
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex regulation 1 1 1 quantitative mass spectrometry evidence
CDC6 YJL194W Essential ATP-binding protein required for DNA replication regulation 1 1 1 quantitative mass spectrometry evidence
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes regulation 1 1 1 quantitative mass spectrometry evidence
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein regulation 1 1 1 quantitative mass spectrometry evidence
MOT1 YPL082C Essential protein involved in regulation of transcription regulation 1 1 1 quantitative mass spectrometry evidence
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) regulation 1 1 1 quantitative mass spectrometry evidence
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly regulation 1 1 1 quantitative mass spectrometry evidence
MET30 YIL046W F-box protein containing five copies of the WD40 motif regulation 1 1 1 quantitative mass spectrometry evidence
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) regulation 1 1 1 quantitative mass spectrometry evidence
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex regulation 1 1 1 quantitative mass spectrometry evidence
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex regulation 1 1 1 quantitative mass spectrometry evidence
NUP1 YOR098C FG-nucleoporin component of central core of the nuclear pore complex regulation 1 1 1 quantitative mass spectrometry evidence
XRS2 YDR369C FHA domain-containing component of the Mre11 complex regulation 1 1 1 quantitative mass spectrometry evidence
FLC1 YPL221W Flavin adenine dinucleotide transporter regulation 1 1 1 quantitative mass spectrometry evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 quantitative mass spectrometry evidence
RGT1 YKL038W Glucose-responsive transcription factor regulation 1 1 1 quantitative mass spectrometry evidence
GSY2 YLR258W Glycogen synthase regulation 1 1 1 quantitative mass spectrometry evidence
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p regulation 1 1 1 quantitative mass spectrometry evidence
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p regulation 1 1 1 quantitative mass spectrometry evidence
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) regulation 1 1 1 quantitative mass spectrometry evidence
GYP7 YDL234C GTPase-activating protein for yeast Rab family members regulation 1 1 1 quantitative mass spectrometry evidence
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p regulation 1 1 1 quantitative mass spectrometry evidence
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) regulation 1 1 1 quantitative mass spectrometry evidence
MUK1 YPL070W Guanine nucleotide exchange factor (GEF) regulation 1 1 1 quantitative mass spectrometry evidence
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors regulation 1 1 1 quantitative mass spectrometry evidence
SYT1 YPR095C Guanine nucleotide exchange factor (GEF) for Arf proteins regulation 1 1 1 quantitative mass spectrometry evidence
BUD3 YCL014W Guanine nucleotide exchange factor (GEF) for Cdc42p regulation 1 1 1 quantitative mass spectrometry evidence
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p regulation 1 1 1 quantitative mass spectrometry evidence
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter regulation 1 1 1 quantitative mass spectrometry evidence
BAP2 YBR068C High-affinity leucine permease regulation 1 1 1 quantitative mass spectrometry evidence
MMP1 YLL061W High-affinity S-methylmethionine permease regulation 1 1 1 quantitative mass spectrometry evidence
GIS1 YDR096W Histone demethylase and transcription factor regulation 1 1 1 quantitative mass spectrometry evidence
YOX1 YML027W Homeobox transcriptional repressor regulation 1 1 1 quantitative mass spectrometry evidence
LYS21 YDL131W Homocitrate synthase isozyme regulation 1 1 1 quantitative mass spectrometry evidence
LYS20 YDL182W Homocitrate synthase isozyme and functions in DNA repair regulation 1 1 1 quantitative mass spectrometry evidence
WAR1 YML076C Homodimeric Zn2Cys6 zinc finger transcription factor regulation 1 1 1 quantitative mass spectrometry evidence
HEH2 YDR458C Inner nuclear membrane (INM) protein regulation 1 1 1 quantitative mass spectrometry evidence
SRC1 YML034W Inner nuclear membrane protein regulation 1 1 1 quantitative mass spectrometry evidence
SPC29 YPL124W Inner plaque spindle pole body (SPB) component regulation 1 1 1 quantitative mass spectrometry evidence
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism regulation 1 1 1 quantitative mass spectrometry evidence
SKG6 YHR149C Integral membrane protein regulation 1 1 1 quantitative mass spectrometry evidence
RPH1 YER169W JmjC domain-containing histone demethylase regulation 1 1 1 quantitative mass spectrometry evidence
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) regulation 1 1 1 quantitative mass spectrometry evidence
TSL1 YML100W Large subunit of trehalose 6-phosphate synthase/phosphatase complex regulation 1 1 1 quantitative mass spectrometry evidence
NVJ2 YPR091C Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) regulation 1 1 1 quantitative mass spectrometry evidence
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis regulation 1 1 1 quantitative mass spectrometry evidence
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily regulation 1 1 1 quantitative mass spectrometry evidence
PAR32 YDL173W Low complexity protein regulation 1 1 1 quantitative mass spectrometry evidence
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway regulation 1 1 1 quantitative mass spectrometry evidence
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway regulation 1 1 1 quantitative mass spectrometry evidence
KAR3 YPR141C Minus-end-directed microtubule motor regulation 1 1 1 quantitative mass spectrometry evidence
MLO50 YLR049C Mitochondrial protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
SAC3 YDR159W mRNA export factor regulation 1 1 1 quantitative mass spectrometry evidence
TGL4 YKR089C Multifunctional lipase/hydrolase/phospholipase regulation 1 1 1 quantitative mass spectrometry evidence
BYE1 YKL005C Negative regulator of transcription elongation regulation 1 1 1 quantitative mass spectrometry evidence
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p regulation 1 1 1 quantitative mass spectrometry evidence
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) regulation 1 1 1 quantitative mass spectrometry evidence
HSL1 YKL101W Nim1p-related protein kinase regulation 1 1 1 quantitative mass spectrometry evidence
FUN19 YAL034C Non-essential protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
TRI1 YMR233W Non-essential sumoylated protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
VTC5 YDR089W Novel subunit of the vacuolar transporter chaperone complex regulation 1 1 1 quantitative mass spectrometry evidence
NVJ1 YHR195W Nuclear envelope protein regulation 1 1 1 quantitative mass spectrometry evidence
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control regulation 1 1 1 quantitative mass spectrometry evidence
CSR2 YPR030W Nuclear ubiquitin protein ligase binding protein regulation 1 1 1 quantitative mass spectrometry evidence
PSO2 YMR137C Nuclease required for DNA single- and double-strand break repair regulation 1 1 1 quantitative mass spectrometry evidence
SPO12 YHR152W Nucleolar protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p regulation 1 1 1 quantitative mass spectrometry evidence
SIP1 YDR422C One of three alternate beta-subunits of the Snf1p kinase complex regulation 1 1 1 quantitative mass spectrometry evidence
CAF120 YNL278W Part of the CCR4-NOT transcriptional regulatory complex regulation 1 1 1 quantitative mass spectrometry evidence
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins regulation 1 1 1 quantitative mass spectrometry evidence
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase regulation 1 1 1 quantitative mass spectrometry evidence
STE5 YDR103W Pheromone-responsive MAPK scaffold protein regulation 1 1 1 quantitative mass spectrometry evidence
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p regulation 1 1 1 quantitative mass spectrometry evidence
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane regulation 1 1 1 quantitative mass spectrometry evidence
PTP3 YER075C Phosphotyrosine-specific protein phosphatase regulation 1 1 1 quantitative mass spectrometry evidence
ALR1 YOL130W Plasma membrane Mg(2+) transporter regulation 1 1 1 quantitative mass spectrometry evidence
CDC5 YMR001C Polo-like kinase required for mitotic exit regulation 1 1 1 quantitative mass spectrometry evidence
INP52 YNL106C Polyphosphatidylinositol phosphatase regulation 1 1 1 quantitative mass spectrometry evidence
INP53 YOR109W Polyphosphatidylinositol phosphatase regulation 1 1 1 quantitative mass spectrometry evidence
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways regulation 1 1 1 quantitative mass spectrometry evidence
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates regulation 1 1 1 quantitative mass spectrometry evidence
BLM10 YFL007W Proteasome activator regulation 1 1 1 quantitative mass spectrometry evidence
STP4 YDL048C Protein containing a Kruppel-type zinc-finger domain regulation 1 1 1 quantitative mass spectrometry evidence
FIR1 YER032W Protein involved in 3' mRNA processing regulation 1 1 1 quantitative mass spectrometry evidence
NBA1 YOL070C Protein involved in axial bud site selection regulation 1 1 1 quantitative mass spectrometry evidence
BUD8 YLR353W Protein involved in bud-site selection regulation 1 1 1 quantitative mass spectrometry evidence
SDS24 YBR214W Protein involved in cell separation during budding regulation 1 1 1 quantitative mass spectrometry evidence
SDS23 YGL056C Protein involved in cell separation during budding regulation 1 1 1 quantitative mass spectrometry evidence
RIF1 YBR275C Protein involved in control of DNA replication regulation 1 1 1 quantitative mass spectrometry evidence
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage regulation 1 1 1 quantitative mass spectrometry evidence
RAD52 YML032C Protein involved in homologous recombination regulation 1 1 1 protein kinase assay evidence
MBR1 YKL093W Protein involved in mitochondrial functions and stress response regulation 1 1 1 quantitative mass spectrometry evidence
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis regulation 1 1 1 quantitative mass spectrometry evidence
SPT2 YER161C Protein involved in negative regulation of transcription regulation 1 1 1 quantitative mass spectrometry evidence
BOI2 YER114C Protein involved in polar growth regulation 1 1 1 quantitative mass spectrometry evidence
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p regulation 1 1 1 quantitative mass spectrometry evidence
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis regulation 1 1 1 quantitative mass spectrometry evidence
NUR1 YDL089W Protein involved in regulation of mitotic exit regulation 1 1 1 quantitative mass spectrometry evidence
STF2 YGR008C Protein involved in resistance to desiccation stress regulation 1 1 1 quantitative mass spectrometry evidence
DOT6 YER088C Protein involved in rRNA and ribosome biogenesis regulation 1 1 1 quantitative mass spectrometry evidence
EPO1 YMR124W Protein involved in septin-ER tethering regulation 1 1 1 quantitative mass spectrometry evidence
ESC1 YMR219W Protein involved in telomeric silencing regulation 1 1 1 quantitative mass spectrometry evidence
SLD3 YGL113W Protein involved in the initiation of DNA replication regulation 1 1 1 quantitative mass spectrometry evidence
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring regulation 1 1 1 quantitative mass spectrometry evidence
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients regulation 1 1 1 quantitative mass spectrometry evidence
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress regulation 1 1 1 quantitative mass spectrometry evidence
KIC1 YHR102W Protein kinase of the PAK/Ste20 family, required for cell integrity regulation 1 1 1 quantitative mass spectrometry evidence
YPL150W YPL150W Protein kinase of unknown cellular role regulation 1 1 1 quantitative mass spectrometry evidence
TDA1 YMR291W Protein kinase of unknown cellular role regulation 1 1 1 quantitative mass spectrometry evidence
FRK1 YPL141C Protein kinase of unknown cellular role regulation 1 1 1 quantitative mass spectrometry evidence
SWE1 YJL187C Protein kinase that regulates the G2/M transition regulation 1 1 1 quantitative mass spectrometry evidence
ZRG8 YER033C Protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
ACF4 YJR083C Protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
MSC3 YLR219W Protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
CSA1 YPR174C Protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
YRB2 YIL063C Protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
YDR239C YDR239C Protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
YLL032C YLL032C Protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
SOK1 YDR006C Protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
GTA1 YEL043W Protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
HER1 YOR227W Protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
PAL1 YDR348C Protein of unknown function thought to be involved in endocytosis regulation 1 1 1 quantitative mass spectrometry evidence
CDC14 YFR028C Protein phosphatase required for mitotic exit regulation 1 1 1 quantitative mass spectrometry evidence
BBC1 YJL020C Protein possibly involved in assembly of actin patches regulation 1 1 1 quantitative mass spectrometry evidence
IGO2 YHR132W-A Protein required for initiation of G0 program regulation 1 1 1 quantitative mass spectrometry evidence
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis regulation 1 1 1 quantitative mass spectrometry evidence
KEL1 YHR158C Protein required for proper cell fusion and cell morphology regulation 1 1 1 quantitative mass spectrometry evidence
LTE1 YAL024C Protein similar to GDP/GTP exchange factors regulation 1 1 1 quantitative mass spectrometry evidence
SQS1 YNL224C Protein that stimulates the ATPase and helicase activities of Prp43p regulation 1 1 1 quantitative mass spectrometry evidence
MIH1 YMR036C Protein tyrosine phosphatase regulation 1 1 1 quantitative mass spectrometry evidence
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start regulation 1 1 1 quantitative mass spectrometry evidence
MDS3 YGL197W Putative component of the TOR regulatory pathway regulation 1 1 1 quantitative mass spectrometry evidence
GYL1 YMR192W Putative GTPase activating protein (GAP) with a role in exocytosis regulation 1 1 1 quantitative mass spectrometry evidence
MST28 YAR033W Putative integral membrane protein, involved in vesicle formation regulation 1 1 1 quantitative mass spectrometry evidence
POR2 YIL114C Putative mitochondrial porin (voltage-dependent anion channel) regulation 1 1 1 quantitative mass spectrometry evidence
YER079W YER079W Putative protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
YGR237C YGR237C Putative protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
TDA11 YHR159W Putative protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
YMR196W YMR196W Putative protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
YNL058C YNL058C Putative protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
YIL024C YIL024C Putative protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
YJL193W YJL193W Putative protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel regulation 1 1 1 quantitative mass spectrometry evidence
GIP2 YER054C Putative regulatory subunit of protein phosphatase Glc7p regulation 1 1 1 quantitative mass spectrometry evidence
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role regulation 1 1 1 quantitative mass spectrometry evidence
LAM5 YFL042C Putative sterol transfer protein regulation 1 1 1 quantitative mass spectrometry evidence
PIG1 YLR273C Putative targeting subunit for type-1 protein phosphatase Glc7p regulation 1 1 1 quantitative mass spectrometry evidence
MSA2 YKR077W Putative transcriptional activator regulation 1 1 1 quantitative mass spectrometry evidence
TOS4 YLR183C Putative transcription factor, contains Forkhead Associated domain regulation 1 1 1 quantitative mass spectrometry evidence
CDC19 YAL038W Pyruvate kinase regulation 1 1 1 quantitative mass spectrometry evidence
STE2 YFL026W Receptor for alpha-factor pheromone regulation 1 1 1 quantitative mass spectrometry evidence
VHS2 YIL135C Regulator of septin dynamics regulation 1 1 1 quantitative mass spectrometry evidence
ASK10 YGR097W Regulator of the Fps1p glycerol channel regulation 1 1 1 quantitative mass spectrometry evidence
GAC1 YOR178C Regulatory subunit for Glc7p type-1 protein phosphatase (PP1) regulation 1 1 1 quantitative mass spectrometry evidence
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex regulation 1 1 1 quantitative mass spectrometry evidence
PSY4 YBL046W Regulatory subunit of protein phosphatase PP4 regulation 1 1 1 quantitative mass spectrometry evidence
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) regulation 1 1 1 quantitative mass spectrometry evidence
TPS3 YMR261C Regulatory subunit of trehalose-6-phosphate synthase/phosphatase regulation 1 1 1 quantitative mass spectrometry evidence
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p regulation 1 1 1 quantitative mass spectrometry evidence
YCL019W YCL019W Retrotransposon TYA Gag and TYB Pol genes regulation 1 1 1 quantitative mass spectrometry evidence
YBL005W-A YBL005W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 quantitative mass spectrometry evidence
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector regulation 1 1 1 quantitative mass spectrometry evidence
BEM2 YER155C Rho GTPase activating protein (RhoGAP) regulation 1 1 1 quantitative mass spectrometry evidence
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) regulation 1 1 1 quantitative mass spectrometry evidence
RPL12B YDR418W Ribosomal 60S subunit protein L12B regulation 1 1 1 quantitative mass spectrometry evidence
REF2 YDR195W RNA-binding protein regulation 1 1 1 quantitative mass spectrometry evidence
SLF1 YDR515W RNA binding protein that associates with polysomes regulation 1 1 1 quantitative mass spectrometry evidence
RPO21 YDL140C RNA polymerase II largest subunit B220 regulation 1 1 1 protein kinase assay evidence
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase regulation 1 1 1 quantitative mass spectrometry evidence
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites regulation 1 1 1 quantitative mass spectrometry evidence
USA1 YML029W Scaffold subunit of the Hrd1p ubiquitin ligase regulation 1 1 1 quantitative mass spectrometry evidence
NTE1 YML059C Serine esterase regulation 1 1 1 quantitative mass spectrometry evidence
MLF3 YNL074C Serine-rich protein of unknown function regulation 1 1 1 quantitative mass spectrometry evidence
KIN4 YOR233W Serine/threonine protein kinase regulation 1 1 1 quantitative mass spectrometry evidence
PTK2 YJR059W Serine/threonine protein kinase regulation 1 1 1 quantitative mass spectrometry evidence
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network regulation 1 1 1 quantitative mass spectrometry evidence
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p regulation 1 1 1 quantitative mass spectrometry evidence
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p regulation 1 1 1 quantitative mass spectrometry evidence
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway regulation 1 1 1 quantitative mass spectrometry evidence
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response regulation 1 1 1 quantitative mass spectrometry evidence
AKL1 YBR059C Ser/Thr protein kinase regulation 1 1 1 quantitative mass spectrometry evidence
FPK1 YNR047W Ser/Thr protein kinase regulation 1 1 1 quantitative mass spectrometry evidence
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein regulation 1 1 1 quantitative mass spectrometry evidence
ALB1 YJL122W Shuttling pre-60S factor regulation 1 1 1 quantitative mass spectrometry evidence
SIR3 YLR442C Silencing protein regulation 1 1 1 quantitative mass spectrometry evidence
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains regulation 1 1 1 quantitative mass spectrometry evidence
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase regulation 1 1 1 quantitative mass spectrometry evidence
FIN1 YDR130C Spindle pole body-related intermediate filament protein regulation 1 1 1 quantitative mass spectrometry evidence
NBP1 YLR457C Spindle pole body (SPB) component regulation 1 1 1 quantitative mass spectrometry evidence
KAR9 YPL269W Spindle positioning factor regulation 1 1 1 quantitative mass spectrometry evidence
YSP2 YDR326C Sterol-binding protein regulation 1 1 1 quantitative mass spectrometry evidence
EGH1 YIR007W Steryl-beta-glucosidase with broad specificity for aglycones regulation 1 1 1 quantitative mass spectrometry evidence
TGL1 YKL140W Steryl ester hydrolase regulation 1 1 1 quantitative mass spectrometry evidence
KIN2 YLR096W S/T protein kinase regulation 1 1 1 quantitative mass spectrometry evidence
RAD51 YER095W Strand exchange protein regulation 1 1 1 protein kinase assay evidence
MSN4 YKL062W Stress-responsive transcriptional activator regulation 1 1 1 quantitative mass spectrometry evidence
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) regulation 1 1 1 quantitative mass spectrometry evidence
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex regulation 1 1 1 quantitative mass spectrometry evidence
HRP1 YOL123W Subunit of cleavage factor I regulation 1 1 1 quantitative mass spectrometry evidence
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) regulation 1 1 1 quantitative mass spectrometry evidence
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) regulation 1 1 1 quantitative mass spectrometry evidence
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex regulation 1 1 1 quantitative mass spectrometry evidence
SMC4 YLR086W Subunit of the condensin complex regulation 1 1 1 quantitative mass spectrometry evidence
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) regulation 1 1 1 quantitative mass spectrometry evidence
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex regulation 1 1 1 quantitative mass spectrometry evidence
ORC2 YBR060C Subunit of the origin recognition complex (ORC) regulation 1 1 1 quantitative mass spectrometry evidence
ORC4 YPR162C Subunit of the origin recognition complex (ORC) regulation 1 1 1 quantitative mass spectrometry evidence
ORC6 YHR118C Subunit of the origin recognition complex (ORC) regulation 1 1 1 quantitative mass spectrometry evidence
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 quantitative mass spectrometry evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 quantitative mass spectrometry evidence
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 quantitative mass spectrometry evidence
HOS4 YIL112W Subunit of the Set3 complex regulation 1 1 1 quantitative mass spectrometry evidence
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) regulation 1 1 1 quantitative mass spectrometry evidence
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) regulation 1 1 1 quantitative mass spectrometry evidence
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) regulation 1 1 1 quantitative mass spectrometry evidence
SIZ1 YDR409W SUMO E3 ligase regulation 1 1 1 quantitative mass spectrometry evidence
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase regulation 1 1 1 quantitative mass spectrometry evidence
TAF4 YMR005W TFIID subunit (48 kDa) regulation 1 1 1 quantitative mass spectrometry evidence
TFA2 YKR062W TFIIE small subunit regulation 1 1 1 quantitative mass spectrometry evidence
TOP2 YNL088W Topoisomerase II regulation 1 1 1 quantitative mass spectrometry evidence
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes regulation 1 1 1 quantitative mass spectrometry evidence
MIG1 YGL035C Transcription factor involved in glucose repression regulation 1 1 1 quantitative mass spectrometry evidence
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis regulation 1 1 1 quantitative mass spectrometry evidence
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes regulation 1 1 1 quantitative mass spectrometry evidence
SSD1 YDR293C Translational repressor regulation 1 1 1 quantitative mass spectrometry evidence
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein regulation 1 1 1 quantitative mass spectrometry evidence
FUN12 YAL035W Translation initiation factor eIF5B regulation 1 1 1 quantitative mass spectrometry evidence
CUE5 YOR042W Ubiquitin-binding protein regulation 1 1 1 quantitative mass spectrometry evidence
UBP2 YOR124C Ubiquitin-specific protease regulation 1 1 1 quantitative mass spectrometry evidence
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p regulation 1 1 1 quantitative mass spectrometry evidence
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex regulation 1 1 1 quantitative mass spectrometry evidence
VSB1 YGR125W Vacuolar membrane protein required for uptake and storage of arginine regulation 1 1 1 quantitative mass spectrometry evidence
VRP1 YLR337C Verprolin, proline-rich actin-associated protein regulation 1 1 1 quantitative mass spectrometry evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Positive Genetic
BRX1 YOL077C Nucleolar protein genetic 1 1 1 Negative Genetic
AXL2 YIL140W Integral plasma membrane protein physical 1 1 1 Biochemical Activity
AXL2 YIL140W Integral plasma membrane protein genetic 1 1 1 Positive Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Phenotypic Enhancement
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex genetic 1 1 1 Dosage Lethality
ABD1 YBR236C Methyltransferase genetic 1 1 1 Dosage Rescue
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme genetic 1 1 1 Negative Genetic
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) genetic 1 1 1 Synthetic Growth Defect
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome physical 1 1 1 Biochemical Activity
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
APC2 YLR127C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 1 1 1 Affinity Capture-MS
APL1 YJR005W Beta-adaptin genetic 1 1 1 Dosage Lethality
APL3 YBL037W Alpha-adaptin genetic 1 1 1 Dosage Lethality
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Negative Genetic
BEM1 YBR200W Protein containing SH3-domains physical 1 1 1 Biochemical Activity
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Dosage Lethality
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 1 1 1 Dosage Lethality
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Synthetic Growth Defect
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Synthetic Growth Defect
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly genetic 1 1 1 Positive Genetic
BOI2 YER114C Protein involved in polar growth physical 1 1 1 Biochemical Activity
BOI2 YER114C Protein involved in polar growth genetic 1 1 1 Dosage Lethality
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Positive Genetic
DAL7 YIR031C Malate synthase physical 1 1 1 Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor physical 1 1 1 Affinity Capture-MS
GSY1 YFR015C Glycogen synthase physical 1 1 1 Affinity Capture-MS
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Dosage Lethality
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Synthetic Lethality
CUP2 YGL166W Copper-binding transcription factor physical 1 1 1 Affinity Capture-Western
CUP2 YGL166W Copper-binding transcription factor genetic 1 1 1 Dosage Lethality
CLA4 YNL298W Cdc42p-activated signal transducing kinase physical 1 1 1 Affinity Capture-Western
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Negative Genetic
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Synthetic Growth Defect
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Affinity Capture-Western
WHI3 YNL197C RNA binding protein that modulates mRNA stability genetic 1 1 1 Phenotypic Enhancement
PDS1 YDR113C Securin genetic 1 1 1 Synthetic Lethality
KAR9 YPL269W Spindle positioning factor genetic 1 1 1 Dosage Lethality
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Synthetic Lethality
SUA7 YPR086W Transcription factor TFIIB physical 1 1 1 Co-localization
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly physical 1 1 1 Co-localization
SPC42 YKL042W Central plaque component of spindle pole body (SPB) genetic 1 1 1 Negative Genetic
PTP2 YOR208W Phosphotyrosine-specific phosphatase physical 1 1 1 Biochemical Activity
PTP3 YER075C Phosphotyrosine-specific protein phosphatase physical 1 1 1 Biochemical Activity
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Biochemical Activity
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 1 1 1 Phenotypic Enhancement
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) physical 1 1 1 Biochemical Activity
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Positive Genetic
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs genetic 1 1 1 Dosage Lethality
FIN1 YDR130C Spindle pole body-related intermediate filament protein genetic 1 1 1 Dosage Lethality
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Dosage Lethality
DDC1 YPL194W DNA damage checkpoint protein genetic 1 1 1 Dosage Lethality
SLD2 YKL108W Single-stranded DNA origin-binding and annealing protein genetic 1 1 1 Dosage Lethality
PRE1 YER012W Beta 4 subunit of the 20S proteasome physical 1 1 1 Co-purification
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Co-purification
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
CYS4 YGR155W Cystathionine beta-synthase physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Negative Genetic
TIF1 YKR059W Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
CNM67 YNL225C Component of the spindle pole body outer plaque genetic 1 1 1 Synthetic Growth Defect
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Dosage Lethality
PCL6 YER059W Pho85p cyclin of the Pho80p subfamily physical 1 1 1 Two-hybrid
SPR6 YER115C Protein of unknown function physical 1 1 1 Two-hybrid
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex physical 1 1 1 Two-hybrid
MSA2 YKR077W Putative transcriptional activator physical 1 1 1 Two-hybrid
MSA2 YKR077W Putative transcriptional activator genetic 1 1 1 Dosage Lethality
SFH1 YLR321C Component of the RSC chromatin remodeling complex physical 1 1 1 Two-hybrid
ZDS2 YML109W Protein with a role in regulating Swe1p-dependent polarized growth physical 1 1 1 Two-hybrid
YMR181C YMR181C Protein of unknown function physical 1 1 1 Two-hybrid
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase physical 1 1 1 Two-hybrid
KAR1 YNL188W Protein involved in karyogamy and spindle pole body duplication physical 1 1 1 Two-hybrid
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway physical 1 1 1 Two-hybrid
HMS1 YOR032C bHLH protein with similarity to myc-family transcription factors physical 1 1 1 Two-hybrid
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine physical 1 1 1 Two-hybrid
SFG1 YOR315W Nuclear protein putative transcription factor genetic 1 1 1 Dosage Lethality
LCB4 YOR171C Sphingoid long-chain base kinase physical 1 1 1 PCA
LCB4 YOR171C Sphingoid long-chain base kinase genetic 1 1 1 Dosage Lethality
SHS1 YDL225W Component of the septin ring that is required for cytokinesis physical 1 1 1 Biochemical Activity
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 1 1 1 Synthetic Growth Defect
MIH1 YMR036C Protein tyrosine phosphatase genetic 1 1 1 Synthetic Rescue
VAC17 YCL063W Phosphoprotein involved in vacuole inheritance physical 1 1 1 Biochemical Activity
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase physical 1 1 1 PCA
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit physical 1 1 1 PCA
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit genetic 1 1 1 Dosage Lethality
THP1 YOL072W Nuclear pore-associated protein physical 1 1 1 PCA
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) physical 1 1 1 PCA
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 1 1 1 PCA
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex physical 1 1 1 PCA
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Positive Genetic
YPT11 YNL304W Rab GTPase physical 1 1 1 PCA
MFT1 YML062C Subunit of the THO complex physical 1 1 1 PCA
NBP1 YLR457C Spindle pole body (SPB) component genetic 1 1 1 Dosage Lethality
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 PCA
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Positive Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Dosage Lethality
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Synthetic Lethality
KIN2 YLR096W S/T protein kinase genetic 1 1 1 Dosage Lethality
KIP1 YBL063W Kinesin-related motor protein physical 1 1 1 Biochemical Activity
ORC1 YML065W Largest subunit of the origin recognition complex genetic 1 1 1 Negative Genetic
RRN6 YBL014C Component of the core factor (CF) rDNA transcription factor complex physical 1 1 1 Biochemical Activity
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Dosage Lethality
SLA1 YBL007C Cytoskeletal protein binding protein physical 1 1 1 Biochemical Activity
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Synthetic Growth Defect
UBP9 YER098W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 1 1 1 Biochemical Activity
PCK1 YKR097W Phosphoenolpyruvate carboxykinase physical 1 1 1 Biochemical Activity
PCK1 YKR097W Phosphoenolpyruvate carboxykinase genetic 1 1 1 Dosage Lethality
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex physical 1 1 1 Biochemical Activity
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
UBX5 YDR330W UBX domain-containing protein that interacts with Cdc48p physical 1 1 1 Biochemical Activity
TDA1 YMR291W Protein kinase of unknown cellular role physical 1 1 1 Biochemical Activity
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role physical 1 1 1 Biochemical Activity
SGS1 YMR190C RecQ family nucleolar DNA helicase physical 1 1 1 Biochemical Activity
RPM2 YML091C Protein subunit of mitochondrial RNase P physical 1 1 1 Biochemical Activity
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Biochemical Activity
YNL284C-A YNL284C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p physical 1 1 1 Biochemical Activity
YDR034C-C YDR034C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YDR239C YDR239C Protein of unknown function physical 1 1 1 Biochemical Activity
SSD1 YDR293C Translational repressor physical 1 1 1 Biochemical Activity
IRC8 YJL051W Bud tip localized protein of unknown function physical 1 1 1 Biochemical Activity
IRC8 YJL051W Bud tip localized protein of unknown function genetic 1 1 1 Dosage Lethality
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation physical 1 1 1 Biochemical Activity
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 1 1 1 Negative Genetic
PDP3 YLR455W Component of the NuA3b histone acetyltransferase complex physical 1 1 1 Biochemical Activity
YPL150W YPL150W Protein kinase of unknown cellular role physical 1 1 1 Biochemical Activity
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen physical 1 1 1 Biochemical Activity
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen genetic 1 1 1 Dosage Rescue
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Biochemical Activity
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Synthetic Growth Defect
VHS2 YIL135C Regulator of septin dynamics physical 1 1 1 Biochemical Activity
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 1 1 1 Biochemical Activity
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis physical 1 1 1 Biochemical Activity
RNH70 YGR276C 3'-5' exoribonuclease physical 1 1 1 Biochemical Activity
YMR155W YMR155W Putative protein of unknown function physical 1 1 1 Biochemical Activity
TRM13 YOL125W 2'-O-methyltransferase physical 1 1 1 Biochemical Activity
YDR042C YDR042C Putative protein of unknown function physical 1 1 1 Biochemical Activity
YPQ1 YOL092W Putative vacuolar membrane transporter for cationic amino acids physical 1 1 1 Biochemical Activity
YHM2 YMR241W Citrate and oxoglutarate carrier protein physical 1 1 1 Biochemical Activity
DLD1 YDL174C Major mitochondrial D-lactate dehydrogenase physical 1 1 1 Biochemical Activity
IMD2 YHR216W Inosine monophosphate dehydrogenase physical 1 1 1 Biochemical Activity
YML083C YML083C Protein of unknown function physical 1 1 1 Biochemical Activity
MET17 YLR303W O-acetyl homoserine-O-acetyl serine sulfhydrylase physical 1 1 1 Biochemical Activity
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase physical 1 1 1 Biochemical Activity
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Dosage Lethality
KDX1 YKL161C Protein kinase physical 1 1 1 PCA
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-Western
HHF2 YNL030W Histone H4 genetic 1 1 1 Dosage Lethality
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex physical 1 1 1 Reconstituted Complex
MTD1 YKR080W NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase physical 1 1 1 Reconstituted Complex
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 Reconstituted Complex
TRP3 YKL211C Indole-3-glycerol-phosphate synthase physical 1 1 1 Reconstituted Complex
YCR016W YCR016W Putative protein of unknown function physical 1 1 1 Reconstituted Complex
YCR016W YCR016W Putative protein of unknown function genetic 1 1 1 Dosage Lethality
SKA1 YKL023W SKI complex-associated protein physical 1 1 1 Reconstituted Complex
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Synthetic Growth Defect
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly genetic 1 1 1 Dosage Lethality
FIR1 YER032W Protein involved in 3' mRNA processing genetic 1 1 1 Dosage Lethality
RTT109 YLL002W Histone acetyltransferase physical 1 1 1 Biochemical Activity
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) physical 1 1 1 Biochemical Activity
TOS8 YGL096W Homeodomain-containing protein and putative transcription factor physical 1 1 1 Biochemical Activity
YHP1 YDR451C Homeobox transcriptional repressor genetic 1 1 1 Dosage Lethality
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Biochemical Activity
NUD1 YOR373W Mitotic exit network (MEN) scaffold protein physical 1 1 1 Biochemical Activity
SPC29 YPL124W Inner plaque spindle pole body (SPB) component physical 1 1 1 Biochemical Activity
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization physical 1 1 1 Biochemical Activity
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion genetic 1 1 1 Synthetic Lethality
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth physical 1 1 1 Biochemical Activity
MBP1 YDL056W Transcription factor physical 1 1 1 PCA
MBP1 YDL056W Transcription factor genetic 1 1 1 Synthetic Growth Defect
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 PCA
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Biochemical Activity
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 PCA
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 1 1 1 PCA
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Synthetic Rescue
GSY2 YLR258W Glycogen synthase physical 1 1 1 PCA
NRM1 YNR009W Transcriptional co-repressor of MBF-regulated gene expression physical 1 1 1 Biochemical Activity
CSA1 YPR174C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Dosage Lethality
HST3 YOR025W Sirtuin, histone H3 deacetylase physical 1 1 1 Biochemical Activity
PAL2 YHR097C Protein involved in clathrin-mediated endocytosis physical 1 1 1 Biochemical Activity
SGN1 YIR001C Cytoplasmic RNA-binding protein physical 1 1 1 Biochemical Activity
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Biochemical Activity
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein genetic 1 1 1 Positive Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Biochemical Activity
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Biochemical Activity
DEF1 YKL054C RNAPII degradation factor genetic 1 1 1 Synthetic Growth Defect
MBF1 YOR298C-A Transcriptional coactivator physical 1 1 1 Biochemical Activity
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs physical 1 1 1 Biochemical Activity
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector physical 1 1 1 Biochemical Activity
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SLD3 YGL113W Protein involved in the initiation of DNA replication physical 1 1 1 Biochemical Activity
SAE2 YGL175C Endonuclease required for telomere elongation genetic 1 1 1 Phenotypic Enhancement
TDH2 YJR009C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 physical 1 1 1 Affinity Capture-MS
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 Affinity Capture-MS
GPM1 YKL152C Tetrameric phosphoglycerate mutase physical 1 1 1 Affinity Capture-MS
RPP2B YDR382W Ribosomal protein P2 beta physical 1 1 1 Affinity Capture-MS
RPL28 YGL103W Ribosomal 60S subunit protein L28 physical 1 1 1 Affinity Capture-MS
RPL28 YGL103W Ribosomal 60S subunit protein L28 genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Phenotypic Suppression
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Dosage Lethality
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-MS
RPP2A YOL039W Ribosomal protein P2 alpha physical 1 1 1 Affinity Capture-MS
RPL9A YGL147C Ribosomal 60S subunit protein L9A physical 1 1 1 Affinity Capture-MS
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 1 1 1 Negative Genetic
RPL6B YLR448W Ribosomal 60S subunit protein L6B physical 1 1 1 Affinity Capture-MS
RPL6B YLR448W Ribosomal 60S subunit protein L6B genetic 1 1 1 Negative Genetic
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 physical 1 1 1 Affinity Capture-MS
RPL15A YLR029C Ribosomal 60S subunit protein L15A physical 1 1 1 Affinity Capture-MS
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
RPL22A YLR061W Ribosomal 60S subunit protein L22A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS31 YLR167W Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin physical 1 1 1 Affinity Capture-MS
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes physical 1 1 1 Affinity Capture-MS
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-MS
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase physical 1 1 1 Affinity Capture-MS
CDC33 YOL139C Translation initiation factor eIF4E physical 1 1 1 Affinity Capture-MS
LEU1 YGL009C Isopropylmalate isomerase physical 1 1 1 Affinity Capture-MS
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL27B YDR471W Ribosomal 60S subunit protein L27B physical 1 1 1 Affinity Capture-MS
RPL31B YLR406C Ribosomal 60S subunit protein L31B physical 1 1 1 Affinity Capture-MS
YLR227W-B YLR227W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SAM1 YLR180W S-adenosylmethionine synthetase physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
RPL30 YGL030W Ribosomal 60S subunit protein L30 physical 1 1 1 Affinity Capture-MS
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 1 1 1 Affinity Capture-MS
RPS17B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RED1 YLR263W Protein component of the synaptonemal complex axial elements physical 1 1 1 Affinity Capture-MS
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase physical 1 1 1 Affinity Capture-MS
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
KRS1 YDR037W Lysyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 1 1 1 Affinity Capture-MS
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus genetic 1 1 1 Positive Genetic
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 1 1 1 Affinity Capture-MS
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-MS
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Positive Genetic
HSP60 YLR259C Tetradecameric mitochondrial chaperonin physical 1 1 1 Affinity Capture-MS
RPO26 YPR187W RNA polymerase subunit ABC23 physical 1 1 1 Affinity Capture-MS
TRX1 YLR043C Cytoplasmic thioredoxin isoenzyme physical 1 1 1 Affinity Capture-MS
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme physical 1 1 1 Affinity Capture-MS
RPS1B YML063W Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel physical 1 1 1 Affinity Capture-MS
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Dosage Lethality
RPL24B YGR148C Ribosomal 60S subunit protein L24B physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone physical 1 1 1 Affinity Capture-MS
MRC1 YCL061C S-phase checkpoint protein required for DNA replication physical 1 1 1 Affinity Capture-MS
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Synthetic Growth Defect
MSH1 YHR120W DNA-binding protein of the mitochondria physical 1 1 1 Affinity Capture-MS
MSH1 YHR120W DNA-binding protein of the mitochondria genetic 1 1 1 Positive Genetic
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 1 1 1 Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
RPL16B YNL069C Ribosomal 60S subunit protein L16B physical 1 1 1 Affinity Capture-MS
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences physical 1 1 1 Affinity Capture-MS
CNE1 YAL058W Calnexin physical 1 1 1 Affinity Capture-MS
RPC19 YNL113W RNA polymerase subunit AC19 physical 1 1 1 Affinity Capture-MS
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex physical 1 1 1 Affinity Capture-MS
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
URA7 YBL039C Major CTP synthase isozyme (see also URA8) physical 1 1 1 Affinity Capture-MS
RPL8B YLL045C Ribosomal 60S subunit protein L8A physical 1 1 1 Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-MS
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 physical 1 1 1 Affinity Capture-MS
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance physical 1 1 1 Affinity Capture-MS
EFB1 YAL003W Translation elongation factor 1 beta physical 1 1 1 Affinity Capture-MS
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis physical 1 1 1 Affinity Capture-MS
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins physical 1 1 1 Affinity Capture-MS
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
SRP40 YKR092C Nucleolar serine-rich protein physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein genetic 1 1 1 Negative Genetic
KAP122 YGL016W Karyopherin beta physical 1 1 1 Affinity Capture-MS
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A genetic 1 1 1 Positive Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
TRM2 YKR056W tRNA methyltransferase physical 1 1 1 Affinity Capture-MS
TIF3 YPR163C Translation initiation factor eIF-4B physical 1 1 1 Affinity Capture-MS
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase physical 1 1 1 Affinity Capture-MS
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Synthetic Growth Defect
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B physical 1 1 1 Affinity Capture-MS
YOR062C YOR062C Protein of unknown function physical 1 1 1 Affinity Capture-MS
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly physical 1 1 1 Affinity Capture-MS
RPC37 YKR025W RNA polymerase III subunit C37 physical 1 1 1 Affinity Capture-MS
YCR087C-A YCR087C-A Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
RPL32 YBL092W Ribosomal 60S subunit protein L32 physical 1 1 1 Affinity Capture-MS
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF physical 1 1 1 Affinity Capture-MS
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) physical 1 1 1 Affinity Capture-MS
TCM62 YBR044C Protein involved in assembly of the succinate dehydrogenase complex physical 1 1 1 Affinity Capture-MS
ZTA1 YBR046C NADPH-dependent quinone reductase physical 1 1 1 Affinity Capture-MS
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering physical 1 1 1 Affinity Capture-MS
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering genetic 1 1 1 Dosage Lethality
LEO1 YOR123C Component of the Paf1 complex physical 1 1 1 Affinity Capture-MS
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Synthetic Growth Defect
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPL14B YHL001W Ribosomal 60S subunit protein L14B physical 1 1 1 Affinity Capture-MS
ERC1 YHR032W Member of the multi-drug and toxin extrusion (MATE) family physical 1 1 1 Affinity Capture-MS
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase physical 1 1 1 Affinity Capture-MS
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 1 1 1 Affinity Capture-MS
RPS14B YJL191W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
FUN12 YAL035W Translation initiation factor eIF5B physical 1 1 1 Affinity Capture-MS
SNF7 YLR025W One of four subunits of the ESCRT-III complex physical 1 1 1 Affinity Capture-MS
VAC8 YEL013W Vacuole-specific Myo2p receptor physical 1 1 1 Affinity Capture-MS
SNU13 YEL026W RNA binding protein physical 1 1 1 Affinity Capture-MS
SNU13 YEL026W RNA binding protein genetic 1 1 1 Negative Genetic
YNL194C YNL194C Integral membrane protein physical 1 1 1 Affinity Capture-MS
KHA1 YJL094C Putative K+/H+ antiporter physical 1 1 1 Affinity Capture-MS
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
PFK26 YIL107C 6-phosphofructo-2-kinase physical 1 1 1 Affinity Capture-MS
LYS12 YIL094C Homo-isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane physical 1 1 1 Affinity Capture-MS
RPL33B YOR234C Ribosomal 60S subunit protein L33B physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) physical 1 1 1 Affinity Capture-MS
PSA1 YDL055C GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) physical 1 1 1 Affinity Capture-MS
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Affinity Capture-MS
RSF2 YJR127C Zinc-finger protein physical 1 1 1 Affinity Capture-MS
RPL17B YJL177W Ribosomal 60S subunit protein L17B physical 1 1 1 Affinity Capture-MS
RPA34 YJL148W RNA polymerase I subunit A34.5 physical 1 1 1 Affinity Capture-MS
URB2 YJR041C Protein required for normal metabolism of the rRNA primary transcript physical 1 1 1 Affinity Capture-MS
URB2 YJR041C Protein required for normal metabolism of the rRNA primary transcript genetic 1 1 1 Negative Genetic
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RAD17 YOR368W Checkpoint protein physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL37A YLR185W Ribosomal 60S subunit protein L37A physical 1 1 1 Affinity Capture-MS
RPL38 YLR325C Ribosomal 60S subunit protein L38 physical 1 1 1 Affinity Capture-MS
RPL38 YLR325C Ribosomal 60S subunit protein L38 genetic 1 1 1 Negative Genetic
RPL4B YDR012W Ribosomal 60S subunit protein L4B physical 1 1 1 Affinity Capture-MS
LYS5 YGL154C Phosphopantetheinyl transferase involved in lysine biosynthesis physical 1 1 1 Affinity Capture-MS
RPL37B YDR500C Ribosomal 60S subunit protein L37B physical 1 1 1 Affinity Capture-MS
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK physical 1 1 1 Affinity Capture-MS
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
IMO32 YGR031W Conserved mitochondrial protein of unknown function physical 1 1 1 Affinity Capture-MS
RPL26B YGR034W Ribosomal 60S subunit protein L26B physical 1 1 1 Affinity Capture-MS
RIE1 YGR250C RNA binding protein and negative regulator of START physical 1 1 1 Affinity Capture-MS
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
TIM11 YDR322C-A Subunit e of mitochondrial F1F0-ATPase physical 1 1 1 Affinity Capture-MS
RPL34A YER056C-A Ribosomal 60S subunit protein L34A physical 1 1 1 Affinity Capture-MS
TIM44 YIL022W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase genetic 1 1 1 Negative Genetic
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I physical 1 1 1 Affinity Capture-MS
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Affinity Capture-MS
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 1 1 1 Dosage Lethality
YDR222W YDR222W Protein of unknown function physical 1 1 1 Affinity Capture-MS
NTE1 YML059C Serine esterase physical 1 1 1 Affinity Capture-MS
SPC2 YML055W Subunit of signal peptidase complex physical 1 1 1 Affinity Capture-MS
SWR1 YDR334W Swi2/Snf2-related ATPase physical 1 1 1 Affinity Capture-MS
ECM38 YLR299W Gamma-glutamyltranspeptidase physical 1 1 1 Affinity Capture-MS
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor physical 1 1 1 Affinity Capture-MS
FPR4 YLR449W Peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
CFT1 YDR301W RNA-binding subunit of the mRNA cleavage and polyadenylation factor physical 1 1 1 Affinity Capture-MS
CDC73 YLR418C Component of the Paf1p complex physical 1 1 1 Affinity Capture-MS
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Growth Defect
YDL129W YDL129W Protein of unknown function physical 1 1 1 Affinity Capture-MS
YDL129W YDL129W Protein of unknown function genetic 1 1 1 Dosage Lethality
TUM1 YOR251C Rhodanese domain sulfur transferase physical 1 1 1 Affinity Capture-MS
MSC6 YOR354C Multicopy suppressor of HER2 involved in mitochondrial translation physical 1 1 1 Affinity Capture-MS
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation physical 1 1 1 Affinity Capture-MS
FLC1 YPL221W Flavin adenine dinucleotide transporter physical 1 1 1 Affinity Capture-MS
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) physical 1 1 1 Affinity Capture-MS
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
RPL7B YPL198W Ribosomal 60S subunit protein L7B physical 1 1 1 Affinity Capture-MS
GYP5 YPL249C GTPase-activating protein (GAP) for yeast Rab family members physical 1 1 1 Affinity Capture-MS
RPL21B YPL079W Ribosomal 60S subunit protein L21B physical 1 1 1 Affinity Capture-MS
RPL13A YDL082W Ribosomal 60S subunit protein L13A physical 1 1 1 Affinity Capture-MS
RPL11B YGR085C Ribosomal 60S subunit protein L11B physical 1 1 1 Affinity Capture-MS
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Negative Genetic
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
ECM3 YOR092W Non-essential protein of unknown function physical 1 1 1 Affinity Capture-MS
RPL20B YOR312C Ribosomal 60S subunit protein L20B physical 1 1 1 Affinity Capture-MS
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B physical 1 1 1 Affinity Capture-MS
RPS24B YIL069C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL1B YGL135W Ribosomal 60S subunit protein L1B physical 1 1 1 Affinity Capture-MS
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL12B YDR418W Ribosomal 60S subunit protein L12B physical 1 1 1 Affinity Capture-MS
RPL19B YBL027W Ribosomal 60S subunit protein L19B physical 1 1 1 Affinity Capture-MS
RPL42B YHR141C Ribosomal 60S subunit protein L42B physical 1 1 1 Affinity Capture-MS
RPL42B YHR141C Ribosomal 60S subunit protein L42B genetic 1 1 1 Synthetic Growth Defect
RPS23B YPR132W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS30B YOR182C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL23B YER117W Ribosomal 60S subunit protein L23B physical 1 1 1 Affinity Capture-MS
RPL2B YIL018W Ribosomal 60S subunit protein L2B physical 1 1 1 Affinity Capture-MS
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL18B YNL301C Ribosomal 60S subunit protein L18B physical 1 1 1 Affinity Capture-MS
RPS18B YML026C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL35B YDL136W Ribosomal 60S subunit protein L35B physical 1 1 1 Affinity Capture-MS
RPL35B YDL136W Ribosomal 60S subunit protein L35B genetic 1 1 1 Negative Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex physical 1 1 1 Biochemical Activity
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p physical 1 1 1 Biochemical Activity
SFI1 YLL003W Centrin (Cdc31p)-binding protein required for SPB duplication genetic 1 1 1 Negative Genetic
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
SAC6 YDR129C Fimbrin, actin-bundling protein physical 1 1 1 Biochemical Activity
CRN1 YLR429W Coronin physical 1 1 1 Biochemical Activity
CRN1 YLR429W Coronin genetic 1 1 1 Dosage Lethality
RTT106 YNL206C Histone chaperone physical 1 1 1 Biochemical Activity
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients physical 1 1 1 Biochemical Activity
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase physical 1 1 1 Biochemical Activity
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease physical 1 1 1 Biochemical Activity
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon physical 1 1 1 Biochemical Activity
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
SPO12 YHR152W Nucleolar protein of unknown function physical 1 1 1 Biochemical Activity
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex physical 1 1 1 Biochemical Activity
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex genetic 1 1 1 Dosage Lethality
FUN30 YAL019W Snf2p family member with ATP-dependent chromatin remodeling activity physical 1 1 1 Biochemical Activity
VMR1 YHL035C Vacuolar membrane protein physical 1 1 1 Biochemical Activity
KCH1 YJR054W Potassium transporter that mediates K+ influx physical 1 1 1 Biochemical Activity
YRF1-6 YNL339C Helicase encoded by the Y' element of subtelomeric regions physical 1 1 1 Biochemical Activity
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis physical 1 1 1 Biochemical Activity
SLK19 YOR195W Kinetochore-associated protein physical 1 1 1 Biochemical Activity
SLK19 YOR195W Kinetochore-associated protein genetic 1 1 1 Dosage Lethality
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase physical 1 1 1 Biochemical Activity
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) physical 1 1 1 Biochemical Activity
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat physical 1 1 1 Biochemical Activity
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains physical 1 1 1 Biochemical Activity
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains genetic 1 1 1 Synthetic Growth Defect
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
SIP3 YNL257C Putative sterol transfer protein physical 1 1 1 Biochemical Activity
CSR2 YPR030W Nuclear ubiquitin protein ligase binding protein physical 1 1 1 Biochemical Activity
YRF1-3 YGR296W Helicase encoded by the Y' element of subtelomeric regions physical 1 1 1 Biochemical Activity
SKG6 YHR149C Integral membrane protein physical 1 1 1 Biochemical Activity
SEC3 YER008C Subunit of the exocyst complex physical 1 1 1 Biochemical Activity
SEC3 YER008C Subunit of the exocyst complex genetic 1 1 1 Synthetic Lethality
MSB1 YOR188W Protein of unknown function physical 1 1 1 Biochemical Activity
MSB1 YOR188W Protein of unknown function genetic 1 1 1 Dosage Lethality
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 1 1 1 Biochemical Activity
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) physical 1 1 1 Biochemical Activity
PHD1 YKL043W Transcriptional activator that enhances pseudohyphal growth physical 1 1 1 Biochemical Activity
YLR035C-A YLR035C-A Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Biochemical Activity
TOS2 YGR221C Protein involved in localization of Cdc24p to the site of bud growth physical 1 1 1 Biochemical Activity
YLR278C YLR278C Zinc-cluster protein physical 1 1 1 Biochemical Activity
FUS1 YCL027W Membrane protein localized to the shmoo tip physical 1 1 1 Biochemical Activity
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 1 1 1 Biochemical Activity
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Dosage Lethality
RBS1 YDL189W Protein involved in assembly of the RNA Pol III complex physical 1 1 1 Biochemical Activity
YER158C YER158C Protein of unknown function physical 1 1 1 Biochemical Activity
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex physical 1 1 1 Biochemical Activity
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane physical 1 1 1 Biochemical Activity
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex physical 1 1 1 Biochemical Activity
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways physical 1 1 1 Biochemical Activity
INO2 YDR123C Transcription factor physical 1 1 1 Biochemical Activity
INO2 YDR123C Transcription factor genetic 1 1 1 Dosage Lethality
MYO3 YKL129C One of two type I myosins physical 1 1 1 Biochemical Activity
VNX1 YNL321W Calcium/H+ antiporter localized to the endoplasmic reticulum membrane physical 1 1 1 Biochemical Activity
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) physical 1 1 1 Biochemical Activity
GIP4 YAL031C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p physical 1 1 1 Biochemical Activity
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Negative Genetic
PAL1 YDR348C Protein of unknown function thought to be involved in endocytosis physical 1 1 1 Biochemical Activity
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p physical 1 1 1 Biochemical Activity
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p genetic 1 1 1 Dosage Lethality
HOS4 YIL112W Subunit of the Set3 complex physical 1 1 1 Biochemical Activity
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Biochemical Activity
TDA11 YHR159W Putative protein of unknown function physical 1 1 1 Biochemical Activity
SPA2 YLL021W Component of the polarisome physical 1 1 1 Biochemical Activity
POG1 YIL122W DNA-binding transcriptional activator physical 1 1 1 Biochemical Activity
POG1 YIL122W DNA-binding transcriptional activator genetic 1 1 1 Dosage Lethality
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Biochemical Activity
DBF20 YPR111W Ser/Thr kinase involved in late nuclear division physical 1 1 1 Biochemical Activity
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes physical 1 1 1 Biochemical Activity
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex physical 1 1 1 Biochemical Activity
NBA1 YOL070C Protein involved in axial bud site selection physical 1 1 1 Biochemical Activity
NBA1 YOL070C Protein involved in axial bud site selection genetic 1 1 1 Negative Genetic
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone physical 1 1 1 Biochemical Activity
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone genetic 1 1 1 Negative Genetic
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Biochemical Activity
TGL4 YKR089C Multifunctional lipase/hydrolase/phospholipase physical 1 1 1 Biochemical Activity
TGL4 YKR089C Multifunctional lipase/hydrolase/phospholipase genetic 1 1 1 Phenotypic Suppression
CYC2 YOR037W Mitochondrial peripheral inner membrane protein physical 1 1 1 Biochemical Activity
CRF1 YDR223W Transcriptional corepressor physical 1 1 1 Biochemical Activity
SRC1 YML034W Inner nuclear membrane protein physical 1 1 1 Biochemical Activity
CST9 YLR394W SUMO E3 ligase physical 1 1 1 Biochemical Activity
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator physical 1 1 1 Biochemical Activity
TFG1 YGR186W TFIIF (Transcription Factor II) largest subunit physical 1 1 1 Biochemical Activity
PKH2 YOL100W Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
NUR1 YDL089W Protein involved in regulation of mitotic exit physical 1 1 1 Biochemical Activity
FMT1 YBL013W Methionyl-tRNA formyltransferase physical 1 1 1 Biochemical Activity
VPS501 YKR078W Vacuolar SNX-BAR protein physical 1 1 1 Biochemical Activity
GAC1 YOR178C Regulatory subunit for Glc7p type-1 protein phosphatase (PP1) physical 1 1 1 Biochemical Activity
PIN2 YOR104W Exomer-dependent cargo protein physical 1 1 1 Biochemical Activity
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) physical 1 1 1 Biochemical Activity
TAF4 YMR005W TFIID subunit (48 kDa) physical 1 1 1 Biochemical Activity
SIT1 YEL065W Ferrioxamine B transporter physical 1 1 1 Biochemical Activity
MSB2 YGR014W Mucin family member involved in various signaling pathways physical 1 1 1 Biochemical Activity
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex physical 1 1 1 Biochemical Activity
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
MMS4 YBR098W Subunit of structure-specific Mms4p-Mus81p endonuclease physical 1 1 1 Biochemical Activity
MMS4 YBR098W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 1 1 1 Synthetic Growth Defect
SPO11 YHL022C Meiosis-specific protein required for meiotic recombination physical 1 1 1 Biochemical Activity
SPO11 YHL022C Meiosis-specific protein required for meiotic recombination genetic 1 1 1 Phenotypic Enhancement
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p physical 1 1 1 Biochemical Activity
PRR1 YKL116C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
YNL058C YNL058C Putative protein of unknown function physical 1 1 1 Biochemical Activity
DUS3 YLR401C Dihydrouridine synthase physical 1 1 1 Biochemical Activity
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein physical 1 1 1 Biochemical Activity
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 1 1 1 Synthetic Growth Defect
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Biochemical Activity
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p physical 1 1 1 Biochemical Activity
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Synthetic Growth Defect
YGL235W YGL235W Putative protein of unknown function physical 1 1 1 Biochemical Activity
KEL1 YHR158C Protein required for proper cell fusion and cell morphology physical 1 1 1 Biochemical Activity
KEL1 YHR158C Protein required for proper cell fusion and cell morphology genetic 1 1 1 Dosage Lethality
MSC3 YLR219W Protein of unknown function physical 1 1 1 Biochemical Activity
YOL036W YOL036W Protein of unknown function physical 1 1 1 Biochemical Activity
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Biochemical Activity
SRM1 YGL097W Nucleotide exchange factor for Gsp1p physical 1 1 1 Biochemical Activity
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
YHL050C YHL050C Putative protein of unknown function physical 1 1 1 Biochemical Activity
JSN1 YJR091C Member of the Puf family of RNA-binding proteins physical 1 1 1 Biochemical Activity
JSN1 YJR091C Member of the Puf family of RNA-binding proteins genetic 1 1 1 Dosage Lethality
RAD30 YDR419W DNA polymerase eta physical 1 1 1 Biochemical Activity
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
LIF1 YGL090W Component of the DNA ligase IV complex physical 1 1 1 Biochemical Activity
SLX4 YLR135W Endonuclease involved in processing DNA physical 1 1 1 Biochemical Activity
SLX4 YLR135W Endonuclease involved in processing DNA genetic 1 1 1 Dosage Lethality
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) physical 1 1 1 Affinity Capture-RNA
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Dosage Lethality
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 1 1 1 Proximity Label-MS
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
DOC1 YGL240W Processivity factor genetic 1 1 1 Synthetic Lethality
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Synthetic Lethality
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator genetic 1 1 1 Synthetic Lethality
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Synthetic Rescue
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Synthetic Lethality
CTF13 YMR094W Subunit of the CBF3 complex genetic 1 1 1 Synthetic Growth Defect
REC102 YLR329W Protein involved in early stages of meiotic recombination genetic 1 1 1 Phenotypic Enhancement
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Phenotypic Suppression
MET14 YKL001C Adenylylsulfate kinase genetic 1 1 1 Positive Genetic
CNB1 YKL190W Calcineurin B genetic 1 1 1 Positive Genetic
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Phenotypic Suppression
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Synthetic Rescue
FLO8 YER109C Transcription factor genetic 1 1 1 Synthetic Rescue
RAD51 YER095W Strand exchange protein genetic 1 1 1 Phenotypic Enhancement
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Phenotypic Enhancement
SLX1 YBR228W Endonuclease involved in DNA recombination and repair genetic 1 1 1 Phenotypic Enhancement
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Phenotypic Enhancement
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Phenotypic Enhancement
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Phenotypic Enhancement
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Phenotypic Enhancement
CSM3 YMR048W Replication fork associated factor genetic 1 1 1 Phenotypic Enhancement
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Phenotypic Enhancement
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
GEP7 YGL057C Protein of unknown function genetic 1 1 1 Negative Genetic
VSB1 YGR125W Vacuolar membrane protein required for uptake and storage of arginine genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Negative Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Negative Genetic
RCF2 YNR018W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
SPE3 YPR069C Spermidine synthase genetic 1 1 1 Negative Genetic
YPR089W YPR089W Protein of unknown function genetic 1 1 1 Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
SIT4 YDL047W Ceramide-activated, type 2A-related serine-threonine phosphatase genetic 1 1 1 Synthetic Lethality
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Phenotypic Suppression
HTB1 YDR224C Histone H2B genetic 1 1 1 Synthetic Lethality
CHS3 YBR023C Chitin synthase III genetic 1 1 1 Synthetic Growth Defect
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Synthetic Growth Defect
FYV4 YHR059W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
HNT3 YOR258W DNA 5' AMP hydrolase involved in DNA repair genetic 1 1 1 Synthetic Growth Defect
MRS1 YIR021W Splicing protein genetic 1 1 1 Synthetic Growth Defect
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response genetic 1 1 1 Synthetic Growth Defect
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Synthetic Growth Defect
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Synthetic Growth Defect
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Synthetic Growth Defect
THR1 YHR025W Homoserine kinase genetic 1 1 1 Synthetic Growth Defect
TUB3 YML124C Alpha-tubulin genetic 1 1 1 Synthetic Growth Defect
DCV1 YFR012W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Synthetic Growth Defect
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 1 1 1 Synthetic Growth Defect
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Synthetic Growth Defect
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Synthetic Growth Defect
IRC15 YPL017C Microtubule associated protein genetic 1 1 1 Synthetic Growth Defect
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Synthetic Growth Defect
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Synthetic Growth Defect
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 1 1 1 Synthetic Growth Defect
NAT3 YPR131C Catalytic subunit of the NatB N-terminal acetyltransferase genetic 1 1 1 Synthetic Growth Defect
PAN2 YGL094C Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 1 1 1 Synthetic Growth Defect
RAI1 YGL246C Nuclear decapping endonuclease genetic 1 1 1 Synthetic Growth Defect
STB5 YHR178W Transcription factor genetic 1 1 1 Synthetic Growth Defect
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Synthetic Growth Defect
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Synthetic Growth Defect
TUP1 YCR084C General repressor of transcription in complex with Cyc8p genetic 1 1 1 Synthetic Growth Defect
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 1 1 1 Synthetic Growth Defect
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Synthetic Growth Defect
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 1 1 1 Synthetic Growth Defect
YGR054W YGR054W Eukaryotic initiation factor eIF2A genetic 1 1 1 Synthetic Growth Defect
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Synthetic Growth Defect
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 1 1 1 Synthetic Growth Defect
PAN3 YKL025C Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 1 1 1 Synthetic Growth Defect
RNR1 YER070W Major isoform of large subunit of ribonucleotide-diphosphate reductase genetic 1 1 1 Synthetic Growth Defect
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Synthetic Growth Defect
FDO1 YMR144W Protein involved in directionality of mating type switching genetic 1 1 1 Synthetic Growth Defect
UBI4 YLL039C Ubiquitin genetic 1 1 1 Dosage Rescue
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 1 1 1 Synthetic Growth Defect
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Synthetic Growth Defect
HST2 YPL015C Cytoplasmic NAD(+)-dependent protein deacetylase genetic 1 1 1 Synthetic Growth Defect
SIR1 YKR101W Protein involved in silencing at mating-type loci HML and HMR genetic 1 1 1 Synthetic Growth Defect
SIR3 YLR442C Silencing protein genetic 1 1 1 Synthetic Growth Defect
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Synthetic Growth Defect
HOS1 YPR068C Class I histone deacetylase (HDAC) family member genetic 1 1 1 Synthetic Growth Defect
NAS6 YGR232W Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 1 1 1 Synthetic Growth Defect
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Synthetic Growth Defect
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Synthetic Growth Defect
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Synthetic Growth Defect
YPK9 YOR291W Vacuolar protein with a possible role in sequestering heavy metals genetic 1 1 1 Synthetic Growth Defect
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 1 1 1 Synthetic Growth Defect
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Synthetic Rescue
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) genetic 1 1 1 Synthetic Growth Defect
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Phenotypic Enhancement
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 1 1 1 Synthetic Growth Defect
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 1 1 1 Synthetic Growth Defect
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Synthetic Growth Defect
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes genetic 1 1 1 Synthetic Growth Defect
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Synthetic Growth Defect
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Synthetic Growth Defect
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Synthetic Growth Defect
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Synthetic Growth Defect
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 1 1 1 Synthetic Growth Defect
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex genetic 1 1 1 Phenotypic Suppression
YPI1 YFR003C Regulatory subunit of the type I protein phosphatase (PP1) Glc7p genetic 1 1 1 Phenotypic Suppression
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Phenotypic Suppression
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Positive Genetic
ORM1 YGR038W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Synthetic Rescue
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Synthetic Rescue
TGL3 YMR313C Bifunctional triacylglycerol lipase and LPE acyltransferase genetic 1 1 1 Phenotypic Suppression
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) genetic 1 1 1 Positive Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Positive Genetic
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) genetic 1 1 1 Positive Genetic
FRQ1 YDR373W N-myristoylated calcium-binding protein genetic 1 1 1 Positive Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Positive Genetic
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Positive Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 1 1 1 Positive Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Positive Genetic
TFC8 YPL007C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Positive Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Positive Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Positive Genetic
NUS1 YDL193W Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 genetic 1 1 1 Positive Genetic
HEM13 YDR044W Coproporphyrinogen III oxidase genetic 1 1 1 Positive Genetic
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Positive Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Positive Genetic
UTP7 YER082C Nucleolar protein genetic 1 1 1 Positive Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Positive Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Positive Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Positive Genetic
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Positive Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Positive Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Positive Genetic
TAF3 YPL011C TFIID subunit (47 kDa) genetic 1 1 1 Positive Genetic
PER1 YCR044C Protein of the endoplasmic reticulum genetic 1 1 1 Positive Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Positive Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Positive Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Positive Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
YDL218W YDL218W Putative protein of unknown function genetic 1 1 1 Positive Genetic
MFB1 YDR219C Mitochondria-associated F-box protein genetic 1 1 1 Positive Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Positive Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Positive Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Positive Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 1 1 1 Positive Genetic
SHY1 YGR112W Mitochondrial inner membrane protein required for complex IV assembly genetic 1 1 1 Positive Genetic
YHL042W YHL042W Endoplasmic reticulum protein genetic 1 1 1 Positive Genetic
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Positive Genetic
YJL136W-A YJL136W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
REC107 YJR021C Protein involved in early stages of meiotic recombination genetic 1 1 1 Positive Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Positive Genetic
NFU1 YKL040C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 1 1 1 Positive Genetic
PER33 YLR064W Protein that localizes to the endoplasmic reticulum genetic 1 1 1 Positive Genetic
YLR154C-H YLR154C-H Putative protein of unknown function genetic 1 1 1 Positive Genetic
RPS29A YLR388W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Positive Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Positive Genetic
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
UTP6 YDR449C Nucleolar protein genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
ERG26 YGL001C C-3 sterol dehydrogenase genetic 1 1 1 Negative Genetic
EMG1 YLR186W Methyltransferase for rRNA genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
NOP14 YDL148C Nucleolar protein genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
FAD1 YDL045C Flavin adenine dinucleotide (FAD) synthetase genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Negative Genetic
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit genetic 1 1 1 Negative Genetic
RPC17 YJL011C RNA polymerase III subunit C17 genetic 1 1 1 Negative Genetic
PHS1 YJL097W Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane genetic 1 1 1 Negative Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Negative Genetic
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
TBF1 YPL128C Telobox-containing general regulatory factor genetic 1 1 1 Negative Genetic
DIB1 YPR082C 17-kDa component of the U4/U6aU5 tri-snRNP genetic 1 1 1 Negative Genetic
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) genetic 1 1 1 Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 1 1 1 Negative Genetic
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex genetic 1 1 1 Negative Genetic
PRP11 YDL043C Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway genetic 1 1 1 Negative Genetic
CDC53 YDL132W Cullin genetic 1 1 1 Negative Genetic
SCM3 YDL139C Nonhistone component of centromeric chromatin genetic 1 1 1 Negative Genetic
RPC53 YDL150W RNA polymerase III subunit C53 genetic 1 1 1 Negative Genetic
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
RPC11 YDR045C RNA polymerase III subunit C11 genetic 1 1 1 Negative Genetic
DOP1 YDR141C Protein involved in vesicular transport at trans-Golgi network (TGN) genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
YDR341C YDR341C Arginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
CDC40 YDR364C Pre-mRNA splicing factor genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
SRB4 YER022W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Negative Genetic
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 1 1 1 Negative Genetic
LSG1 YGL099W Putative GTPase involved in 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
VHT1 YGR065C High-affinity plasma membrane H+-biotin (vitamin H) symporter genetic 1 1 1 Negative Genetic
NOP7 YGR103W Component of several different pre-ribosomal particles genetic 1 1 1 Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
IPI1 YHR085W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Negative Genetic
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
UTP9 YHR196W Nucleolar protein genetic 1 1 1 Negative Genetic
THS1 YIL078W Threonyl-tRNA synthetase genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
HCA4 YJL033W DEAD box RNA helicase genetic 1 1 1 Negative Genetic
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
MIF2 YKL089W Centromeric CDEIII region binding protein genetic 1 1 1 Negative Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Negative Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Negative Genetic
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly genetic 1 1 1 Negative Genetic
GRC3 YLL035W Polynucleotide kinase present on rDNA genetic 1 1 1 Negative Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
DML1 YMR211W Essential protein involved in mtDNA inheritance genetic 1 1 1 Negative Genetic
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 1 1 1 Negative Genetic
TIF11 YMR260C Translation initiation factor eIF1A genetic 1 1 1 Negative Genetic
HAS1 YMR290C ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
RPC31 YNL151C RNA polymerase III subunit C31 genetic 1 1 1 Negative Genetic
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
CRS1 YNL247W Cysteinyl-tRNA synthetase genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
THI80 YOR143C Thiamine pyrophosphokinase genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
HTS1 YPR033C Cytoplasmic and mitochondrial histidine tRNA synthetase genetic 1 1 1 Negative Genetic
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription genetic 1 1 1 Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Negative Genetic
RXT3 YDL076C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
GIS1 YDR096W Histone demethylase and transcription factor genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PSP1 YDR505C Asn and gln rich protein of unknown function genetic 1 1 1 Negative Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Negative Genetic
YHR045W YHR045W Putative protein of unknown function genetic 1 1 1 Negative Genetic
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
TCD2 YKL027W tRNA threonylcarbamoyladenosine dehydratase genetic 1 1 1 Negative Genetic
YKL075C YKL075C Putative protein of unknown function genetic 1 1 1 Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Negative Genetic
LOS1 YKL205W Nuclear pore protein genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
VTA1 YLR181C Multivesicular body (MVB) protein genetic 1 1 1 Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Negative Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Negative Genetic
TRM11 YOL124C Catalytic subunit of adoMet-dependent tRNA methyltransferase complex genetic 1 1 1 Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Negative Genetic
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Negative Genetic
PCL8 YPL219W Cyclin genetic 1 1 1 Negative Genetic
YPL225W YPL225W Protein of unknown function genetic 1 1 1 Negative Genetic
MRL1 YPR079W Membrane protein genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
EGH1 YIR007W Steryl-beta-glucosidase with broad specificity for aglycones genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Negative Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PPR1 YLR014C Zinc finger transcription factor genetic 1 1 1 Negative Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Negative Genetic
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
MDM36 YPR083W Mitochondrial protein genetic 1 1 1 Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
PHO11 YAR071W One of three repressible acid phosphatases genetic 1 1 1 Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
KTI11 YBL071W-A Zn-ribbon protein that co-purifies with Dph1 and Dph2 genetic 1 1 1 Negative Genetic
YBR085C-A YBR085C-A Protein of unknown function genetic 1 1 1 Negative Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
YCL068C YCL068C Putative protein of unknown function genetic 1 1 1 Negative Genetic
CTO1 YCR015C Protein required for cold tolerance genetic 1 1 1 Negative Genetic
HTL1 YCR020W-B Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RRT12 YCR045C Probable subtilisin-family protease genetic 1 1 1 Negative Genetic
YDL057W YDL057W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SYO1 YDL063C Transport adaptor or symportin genetic 1 1 1 Negative Genetic
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 1 1 1 Negative Genetic
RGT2 YDL138W Plasma membrane high glucose sensor that regulates glucose transport genetic 1 1 1 Negative Genetic
YDL144C YDL144C Protein of unknown function genetic 1 1 1 Negative Genetic
MGT1 YDL200C DNA repair methyltransferase (6-O-methylguanine-DNA methylase) genetic 1 1 1 Negative Genetic
YDL211C YDL211C Protein of unknown function genetic 1 1 1 Negative Genetic
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
NSI1 YDR026C RNA polymerase I termination factor genetic 1 1 1 Negative Genetic
VTC5 YDR089W Novel subunit of the vacuolar transporter chaperone complex genetic 1 1 1 Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
YCF1 YDR135C Vacuolar glutathione S-conjugate transporter genetic 1 1 1 Negative Genetic
YDR194W-A YDR194W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
REF2 YDR195W RNA-binding protein genetic 1 1 1 Negative Genetic
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 1 1 1 Negative Genetic
EBS1 YDR206W Protein involved in translation inhibition and nonsense-mediated decay genetic 1 1 1 Negative Genetic
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p genetic 1 1 1 Negative Genetic
YDR444W YDR444W Putative hydrolase acting on ester bonds genetic 1 1 1 Negative Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Negative Genetic
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome genetic 1 1 1 Negative Genetic
VPS60 YDR486C Protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
YDR524C-B YDR524C-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
MIT1 YEL007W Transcriptional regulator of pseudohyphal growth genetic 1 1 1 Negative Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
YEL076C YEL076C Putative protein of unknown function genetic 1 1 1 Negative Genetic
MXR1 YER042W Methionine-S-sulfoxide reductase genetic 1 1 1 Negative Genetic
YER076C YER076C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Negative Genetic
RPL24A YGL031C Ribosomal 60S subunit protein L24A genetic 1 1 1 Negative Genetic
PUS2 YGL063W Mitochondrial tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
EAT1 YGR015C Ethanol acetyltransferase genetic 1 1 1 Negative Genetic
LST7 YGR057C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
YGR204C-A YGR204C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Negative Genetic
YGR273C YGR273C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR283C YGR283C Putative methyltransferase genetic 1 1 1 Negative Genetic
YLF2 YHL014C Protein of unknown function genetic 1 1 1 Negative Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Negative Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 1 1 1 Negative Genetic
NDT80 YHR124W Meiosis-specific transcription factor genetic 1 1 1 Negative Genetic
CTR2 YHR175W Low-affinity copper transporter of the vacuolar membrane genetic 1 1 1 Negative Genetic
PDR11 YIL013C ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein genetic 1 1 1 Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Negative Genetic
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase genetic 1 1 1 Negative Genetic
DPI8 YJL133C-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis genetic 1 1 1 Negative Genetic
YJL193W YJL193W Putative protein of unknown function genetic 1 1 1 Negative Genetic
GEA1 YJR031C Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) genetic 1 1 1 Negative Genetic
HIT1 YJR055W Protein involved in C/D snoRNP assembly genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
THI11 YJR156C Protein involved in synthesis of the thiamine precursor HMP genetic 1 1 1 Negative Genetic
COS5 YJR161C Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 1 1 1 Negative Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
FOX2 YKR009C 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase genetic 1 1 1 Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Negative Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
DPA10 YLR307C-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Negative Genetic
DIF1 YLR437C Protein that regulates nuclear import of Rnr2p and Rnr4p genetic 1 1 1 Negative Genetic
RSF1 YMR030W Protein required for respiratory growth genetic 1 1 1 Negative Genetic
HFD1 YMR110C Dehydrogenase involved in ubiquinone and sphingolipid metabolism genetic 1 1 1 Negative Genetic
GYL1 YMR192W Putative GTPase activating protein (GAP) with a role in exocytosis genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RIT1 YMR283C Initiator methionine 2'-O-ribosyl phosphate transferase genetic 1 1 1 Negative Genetic
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 1 1 1 Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
RPL9B YNL067W Ribosomal 60S subunit protein L9B genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
DGR1 YNL130C-A Protein of unknown function genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
IBD2 YNL164C Component of the BUB2-dependent spindle checkpoint pathway genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 1 1 1 Negative Genetic
MET2 YNL277W L-homoserine-O-acetyltransferase genetic 1 1 1 Negative Genetic
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 1 1 1 Negative Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Negative Genetic
MPP6 YNR024W Nuclear exosome-associated RNA binding protein genetic 1 1 1 Negative Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 1 1 1 Negative Genetic
PDR18 YNR070W Transporter of the ATP-binding cassette (ABC) family genetic 1 1 1 Negative Genetic
MAN2 YNR073C Mannitol dehydrogenase genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
MHF1 YOL086W-A Component of the heterotetrameric MHF histone-fold complex genetic 1 1 1 Negative Genetic
YOR032W-A YOR032W-A Protein of unknown function genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
SRL1 YOR247W Mannoprotein that exhibits a tight association with the cell wall genetic 1 1 1 Negative Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Negative Genetic
YOR394C-A YOR394C-A Protein of unknown function genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
YPL060C-A YPL060C-A TyA Gag protein genetic 1 1 1 Negative Genetic
HTC1 YPL067C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RNY1 YPL123C Vacuolar RNase of the T(2) family genetic 1 1 1 Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex genetic 1 1 1 Negative Genetic
COA2 YPL189C-A Cytochrome oxidase assembly factor genetic 1 1 1 Negative Genetic
YPL245W YPL245W Putative protein of unknown function genetic 1 1 1 Negative Genetic
KEL3 YPL263C Cytoplasmic protein of unknown function genetic 1 1 1 Negative Genetic
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
FEX2 YPL279C Protein involved in fluoride export genetic 1 1 1 Negative Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Dosage Lethality
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Dosage Lethality
NHP6B YBR089C-A High-mobility group (HMG) protein genetic 1 1 1 Dosage Lethality
RGT1 YKL038W Glucose-responsive transcription factor genetic 1 1 1 Dosage Lethality
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 1 1 1 Dosage Lethality
USV1 YPL230W Putative transcription factor containing a C2H2 zinc finger genetic 1 1 1 Dosage Lethality
HMRA2 YCR096C Silenced copy of a2 at HMR genetic 1 1 1 Dosage Lethality
YPR015C YPR015C Putative zinc finger transcription factor genetic 1 1 1 Dosage Lethality
FZF1 YGL254W Transcription factor involved in sulfite metabolism genetic 1 1 1 Dosage Lethality
TOG1 YER184C Transcriptional activator of oleate genes genetic 1 1 1 Dosage Lethality
YAP3 YHL009C Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Dosage Lethality
PDR8 YLR266C Transcription factor genetic 1 1 1 Dosage Lethality
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes genetic 1 1 1 Dosage Lethality
DAP2 YHR028C Dipeptidyl aminopeptidase genetic 1 1 1 Positive Genetic
FLO1 YAR050W Lectin-like protein involved in flocculation genetic 1 1 1 Dosage Lethality
PDR3 YBL005W Transcriptional activator of the pleiotropic drug resistance network genetic 1 1 1 Dosage Lethality
RIB1 YBL033C GTP cyclohydrolase II genetic 1 1 1 Dosage Lethality
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Dosage Lethality
PSY4 YBL046W Regulatory subunit of protein phosphatase PP4 genetic 1 1 1 Dosage Lethality
YEL1 YBL060W Guanine nucleotide exchange factor specific for Arf3p genetic 1 1 1 Dosage Lethality
ROX3 YBL093C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Dosage Lethality
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Dosage Lethality
RKM3 YBR030W Ribosomal lysine methyltransferase genetic 1 1 1 Dosage Lethality
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 1 1 1 Dosage Lethality
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Dosage Lethality
YSW1 YBR148W Protein required for normal prospore membrane formation genetic 1 1 1 Dosage Lethality
KTR4 YBR199W Glycosyltransferase involved in protein glycosylation genetic 1 1 1 Dosage Lethality
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs genetic 1 1 1 Dosage Lethality
YPT10 YBR264C Rab family GTP-binding protein genetic 1 1 1 Dosage Lethality
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Dosage Lethality
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint genetic 1 1 1 Dosage Lethality
SRO9 YCL037C Cytoplasmic RNA-binding protein genetic 1 1 1 Dosage Lethality
KAR4 YCL055W Transcription factor required for response to pheromones genetic 1 1 1 Dosage Lethality
CIT2 YCR005C Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle genetic 1 1 1 Dosage Lethality
MATALPHA2 YCR039C Homeobox-domain protein genetic 1 1 1 Dosage Lethality
FUB1 YCR076C Proteasome-binding protein genetic 1 1 1 Dosage Lethality
KNH1 YDL049C Protein with similarity to Kre9p genetic 1 1 1 Dosage Lethality
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA genetic 1 1 1 Dosage Lethality
THI3 YDL080C Regulatory protein that binds Pdc2p and Thi2p transcription factors genetic 1 1 1 Dosage Lethality
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export genetic 1 1 1 Dosage Lethality
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 1 1 1 Dosage Lethality
LYS21 YDL131W Homocitrate synthase isozyme genetic 1 1 1 Dosage Lethality
RDI1 YDL135C Rho GDP dissociation inhibitor genetic 1 1 1 Dosage Lethality
UGX2 YDL169C Protein of unknown function genetic 1 1 1 Dosage Lethality
SNF3 YDL194W Plasma membrane low glucose sensor, regulates glucose transport genetic 1 1 1 Dosage Lethality
CWC2 YDL209C Member of the NineTeen Complex (NTC) genetic 1 1 1 Dosage Lethality
FMP45 YDL222C Integral membrane protein localized to mitochondria genetic 1 1 1 Dosage Lethality
SOK1 YDR006C Protein of unknown function genetic 1 1 1 Dosage Lethality
MAK21 YDR060W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Dosage Lethality
STE5 YDR103W Pheromone-responsive MAPK scaffold protein genetic 1 1 1 Dosage Lethality
YDR124W YDR124W Mitochondrial protein of unknown function genetic 1 1 1 Dosage Lethality
MRX16 YDR132C Protein that associates with the large mitoribosomal subunit genetic 1 1 1 Dosage Lethality
STB3 YDR169C Ribosomal RNA processing element (RRPE)-binding protein genetic 1 1 1 Dosage Lethality
HST4 YDR191W NAD(+)-dependent protein deacetylase genetic 1 1 1 Dosage Lethality
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 1 1 1 Dosage Lethality
PRP28 YDR243C Pre-mRNA splicing factor genetic 1 1 1 Dosage Lethality
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Dosage Lethality
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase genetic 1 1 1 Dosage Lethality
YDR249C YDR249C Putative protein of unknown function genetic 1 1 1 Dosage Lethality
PAM1 YDR251W Essential protein of unknown function genetic 1 1 1 Dosage Lethality
RKM4 YDR257C Ribosomal lysine methyltransferase genetic 1 1 1 Dosage Lethality
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Dosage Lethality
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Dosage Lethality
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Dosage Lethality
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Dosage Lethality
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor genetic 1 1 1 Dosage Lethality
CIN10 YDR387C Putative transporter genetic 1 1 1 Dosage Lethality
UBA2 YDR390C Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Aos1p genetic 1 1 1 Dosage Lethality
TRS120 YDR407C Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Dosage Lethality
SPG3 YDR504C Protein required for high temperature survival during stationary phase genetic 1 1 1 Dosage Lethality
SPS1 YDR523C STE20-family GCKIII protein kinase genetic 1 1 1 Dosage Lethality
UBC8 YEL012W Ubiquitin-conjugating enzyme that regulates gluconeogenesis genetic 1 1 1 Dosage Lethality
YEL025C YEL025C Putative protein of unknown function genetic 1 1 1 Dosage Lethality
GTA1 YEL043W Protein of unknown function genetic 1 1 1 Dosage Lethality
GLY1 YEL046C Threonine aldolase genetic 1 1 1 Dosage Lethality
PHM8 YER037W Lysophosphatidic acid (LPA) phosphatase, nucleotidase genetic 1 1 1 Dosage Lethality
TPA1 YER049W Prolyl hydroxylase genetic 1 1 1 Dosage Lethality
RSM18 YER050C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Dosage Lethality
FCY21 YER060W Putative purine-cytosine permease genetic 1 1 1 Dosage Lethality
SPT15 YER148W TATA-binding protein (TBP) genetic 1 1 1 Dosage Lethality
YER152C YER152C Protein with 2-aminoadipate transaminase activity genetic 1 1 1 Dosage Lethality
MYG1 YER156C Protein involved in mitochondrial function genetic 1 1 1 Dosage Lethality
VTC2 YFL004W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Dosage Lethality
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Dosage Lethality
GYP8 YFL027C GTPase-activating protein for yeast Rab family members genetic 1 1 1 Dosage Lethality
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Dosage Lethality
CLG1 YGL215W Cyclin-like protein that interacts with Pho85p genetic 1 1 1 Dosage Lethality
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation genetic 1 1 1 Dosage Lethality
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex genetic 1 1 1 Dosage Lethality
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins genetic 1 1 1 Dosage Lethality
MTE1 YGR042W Protein of unknown function genetic 1 1 1 Dosage Lethality
ROM1 YGR070W Guanine nucleotide exchange factor (GEF) for Rho1p genetic 1 1 1 Dosage Lethality
PEX8 YGR077C Intraperoxisomal organizer of the peroxisomal import machinery genetic 1 1 1 Dosage Lethality
PRP31 YGR091W Splicing factor genetic 1 1 1 Dosage Lethality
ECL1 YGR146C Protein of unknown function genetic 1 1 1 Dosage Lethality
HIP1 YGR191W High-affinity histidine permease genetic 1 1 1 Dosage Lethality
ZPR1 YGR211W Essential protein with two zinc fingers genetic 1 1 1 Dosage Lethality
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Dosage Lethality
YGR266W YGR266W Protein of unknown function genetic 1 1 1 Dosage Lethality
YHL008C YHL008C Putative protein of unknown function genetic 1 1 1 Dosage Lethality
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Dosage Lethality
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Dosage Lethality
PPE1 YHR075C Protein with carboxyl methyl esterase activity genetic 1 1 1 Dosage Lethality
DMA1 YHR115C Ubiquitin-protein ligase (E3) genetic 1 1 1 Dosage Lethality
YHR138C YHR138C Protein of unknown function genetic 1 1 1 Dosage Lethality
SPO16 YHR153C Meiosis-specific protein involved in synaptonemal complex assembly genetic 1 1 1 Dosage Lethality
LIN1 YHR156C Non-essential component of U5 snRNP genetic 1 1 1 Dosage Lethality
PRP8 YHR165C Component of U4/U6-U5 snRNP complex genetic 1 1 1 Dosage Lethality
RGD3 YHR182W GTPase activating protein (GAP) for Rho3p, involved in cell polarity g genetic 1 1 1 Dosage Lethality
PFS1 YHR185C Sporulation protein required for prospore membrane formation genetic 1 1 1 Dosage Lethality
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Dosage Lethality
VHR1 YIL056W Transcriptional activator genetic 1 1 1 Dosage Lethality
KTR7 YIL085C Putative mannosyltransferase involved in protein glycosylation genetic 1 1 1 Dosage Lethality
UTP25 YIL091C Nucleolar protein genetic 1 1 1 Dosage Lethality
ESL1 YIL151C hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Dosage Lethality
COA1 YIL157C Mitochondrial inner membrane protein genetic 1 1 1 Dosage Lethality
MND2 YIR025W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Dosage Lethality
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum genetic 1 1 1 Dosage Lethality
MTR4 YJL050W RNA duplex-sensing translocase genetic 1 1 1 Dosage Lethality
IKS1 YJL057C Protein kinase of unknown cellular role genetic 1 1 1 Dosage Lethality
SIP4 YJL089W C6 zinc cluster transcriptional activator genetic 1 1 1 Dosage Lethality
GSM1 YJL103C Putative zinc cluster protein of unknown function genetic 1 1 1 Dosage Lethality
SET4 YJL105W Chromatin-associated protein involved in control of stress response genetic 1 1 1 Dosage Lethality
YJL107C YJL107C Putative protein of unknown function genetic 1 1 1 Dosage Lethality
TRK1 YJL129C Component of the Trk1p-Trk2p potassium transport system genetic 1 1 1 Dosage Lethality
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Dosage Lethality
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Dosage Lethality
RAD7 YJR052W Nucleotide excision repair (NER) protein genetic 1 1 1 Dosage Lethality
JHD2 YJR119C JmjC domain family histone demethylase genetic 1 1 1 Dosage Lethality
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex genetic 1 1 1 Dosage Lethality
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Dosage Lethality
CWP2 YKL096W-A Covalently linked cell wall mannoprotein genetic 1 1 1 Dosage Lethality
YPK1 YKL126W S/T protein kinase genetic 1 1 1 Dosage Lethality
LTV1 YKL143W Subunit of the EGO/GSE complex genetic 1 1 1 Dosage Lethality
LOT5 YKL183W Protein of unknown function genetic 1 1 1 Dosage Lethality
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Dosage Lethality
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 1 1 1 Dosage Lethality
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation genetic 1 1 1 Dosage Lethality
YKR041W YKR041W Protein of unknown function genetic 1 1 1 Dosage Lethality
TFA2 YKR062W TFIIE small subunit genetic 1 1 1 Dosage Lethality
TRZ1 YKR079C tRNA 3'-end processing endonuclease tRNase Z genetic 1 1 1 Dosage Lethality
ESL2 YKR096W hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Dosage Lethality
LOT6 YLR011W FMN-dependent NAD(P)H:quinone reductase genetic 1 1 1 Dosage Lethality
GAT3 YLR013W Protein containing GATA family zinc finger motifs genetic 1 1 1 Dosage Lethality
MLH2 YLR035C Protein involved in mismatch repair and meiotic recombination genetic 1 1 1 Dosage Lethality
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Dosage Lethality
LAM6 YLR072W Sterol transporter that transfers sterols between membranes genetic 1 1 1 Dosage Lethality
SRL2 YLR082C Protein of unknown function genetic 1 1 1 Dosage Lethality
IOC2 YLR095C Subunit of the Isw1b complex genetic 1 1 1 Dosage Lethality
HRT3 YLR097C Putative SCF-ubiquitin ligase F-box protein genetic 1 1 1 Dosage Lethality
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly genetic 1 1 1 Dosage Lethality
CSC1 YLR241W Calcium permeable gated cation channel genetic 1 1 1 Dosage Lethality
YLR297W YLR297W Protein of unknown function genetic 1 1 1 Dosage Lethality
CWC24 YLR323C General splicing factor genetic 1 1 1 Dosage Lethality
MID2 YLR332W O-glycosylated plasma membrane protein genetic 1 1 1 Dosage Lethality
ELO3 YLR372W Elongase genetic 1 1 1 Dosage Lethality
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Dosage Lethality
RIF2 YLR453C Protein that binds to the Rap1p C-terminus genetic 1 1 1 Dosage Lethality
TAF11 YML015C TFIID subunit (40 kDa) genetic 1 1 1 Dosage Lethality
YML053C YML053C Putative protein of unknown function genetic 1 1 1 Dosage Lethality
YML082W YML082W Putative protein predicted to have carbon-sulfur lyase activity genetic 1 1 1 Dosage Lethality
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs genetic 1 1 1 Dosage Lethality
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Dosage Lethality
SRT1 YMR101C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Dosage Lethality
JLP2 YMR132C Protein of unknown function genetic 1 1 1 Dosage Lethality
REC114 YMR133W Protein involved in early stages of meiotic recombination genetic 1 1 1 Dosage Lethality
PSO2 YMR137C Nuclease required for DNA single- and double-strand break repair genetic 1 1 1 Dosage Lethality
RIM11 YMR139W Protein kinase genetic 1 1 1 Dosage Lethality
ICY1 YMR195W Protein of unknown function genetic 1 1 1 Dosage Lethality
INP1 YMR204C Peripheral membrane protein of peroxisomes genetic 1 1 1 Dosage Lethality
EFR3 YMR212C Protein required for Stt4-containing PI kinase complex localization genetic 1 1 1 Dosage Lethality
ESC1 YMR219W Protein involved in telomeric silencing genetic 1 1 1 Dosage Lethality
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein genetic 1 1 1 Dosage Lethality
YME2 YMR302C Integral inner mitochondrial membrane protein genetic 1 1 1 Dosage Lethality
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination genetic 1 1 1 Dosage Lethality
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) genetic 1 1 1 Dosage Lethality
GCD10 YNL062C Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p genetic 1 1 1 Dosage Lethality
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) genetic 1 1 1 Dosage Lethality
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Dosage Lethality
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Dosage Lethality
MGS1 YNL218W Protein with DNA-dependent ATPase and ssDNA annealing activities genetic 1 1 1 Dosage Lethality
SEC21 YNL287W Gamma subunit of coatomer genetic 1 1 1 Dosage Lethality
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p genetic 1 1 1 Dosage Lethality
TOS6 YNL300W Glycosylphosphatidylinositol-dependent cell wall protein genetic 1 1 1 Dosage Lethality
DAL82 YNL314W Positive regulator of allophanate inducible genes genetic 1 1 1 Dosage Lethality
ZRG17 YNR039C Endoplasmic reticulum zinc transporter genetic 1 1 1 Dosage Lethality
PUL4 YNR063W Putative zinc-cluster transcription factor genetic 1 1 1 Dosage Lethality
PHO80 YOL001W Cyclin genetic 1 1 1 Dosage Lethality
YAP7 YOL028C Transcriptional repressor of nitric oxide oxidase genetic 1 1 1 Dosage Lethality
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Dosage Lethality
PFK27 YOL136C 6-phosphofructo-2-kinase genetic 1 1 1 Dosage Lethality
HPF1 YOL155C Haze-protective mannoprotein genetic 1 1 1 Dosage Lethality
TIR4 YOR009W Cell wall mannoprotein genetic 1 1 1 Dosage Lethality
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease genetic 1 1 1 Dosage Lethality
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Dosage Lethality
NRT1 YOR071C High-affinity nicotinamide riboside transporter genetic 1 1 1 Dosage Lethality
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation genetic 1 1 1 Dosage Lethality
TRS33 YOR115C Core component of TRAPP complexes I, II and IV genetic 1 1 1 Dosage Lethality
UBP2 YOR124C Ubiquitin-specific protease genetic 1 1 1 Dosage Lethality
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor genetic 1 1 1 Dosage Lethality
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
SWT1 YOR166C RNA endoribonuclease involved in perinuclear mRNP quality control genetic 1 1 1 Dosage Lethality
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway genetic 1 1 1 Dosage Lethality
PUS7 YOR243C Pseudouridine synthase genetic 1 1 1 Dosage Lethality
HUA2 YOR284W Cytoplasmic protein of unknown function genetic 1 1 1 Dosage Lethality
SLY41 YOR307C Protein involved in ER-to-Golgi transport genetic 1 1 1 Dosage Lethality
TEA1 YOR337W Ty1 enhancer activator involved in Ty enhancer-mediated transcription genetic 1 1 1 Dosage Lethality
TFB6 YOR352W Subunit of TFIIH complex genetic 1 1 1 Dosage Lethality
SCP1 YOR367W Component of yeast cortical actin cytoskeleton genetic 1 1 1 Dosage Lethality
FIT3 YOR383C Mannoprotein that is incorporated into the cell wall genetic 1 1 1 Dosage Lethality
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Dosage Lethality
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Dosage Lethality
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Dosage Lethality
DBP1 YPL119C ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Dosage Lethality
SPO19 YPL130W Meiosis-specific prospore protein genetic 1 1 1 Dosage Lethality
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 1 1 1 Dosage Lethality
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Dosage Lethality
SUI3 YPL237W Beta subunit of the translation initiation factor eIF2 genetic 1 1 1 Dosage Lethality
REC8 YPR007C Meiosis-specific component of the sister chromatid cohesion complex genetic 1 1 1 Dosage Lethality
NOT5 YPR072W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Dosage Lethality
RRP15 YPR143W Nucleolar protein genetic 1 1 1 Dosage Lethality
NOC4 YPR144C Nucleolar protein genetic 1 1 1 Dosage Lethality
JIP5 YPR169W Protein required for biogenesis of the large ribosomal subunit genetic 1 1 1 Dosage Lethality
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Rescue
RCF3 YBR255C-A Mitochondrial inner membrane protein genetic 1 1 1 Dosage Rescue
USO1 YDL058W Essential protein involved in vesicle-mediated ER to Golgi transport genetic 1 1 1 Dosage Rescue
COX9 YDL067C Subunit VIIa of cytochrome c oxidase (Complex IV) genetic 1 1 1 Dosage Rescue
RCR2 YDR003W Vacuolar ubiquitin ligase-substrate adaptor genetic 1 1 1 Dosage Rescue
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p genetic 1 1 1 Dosage Rescue
SUT1 YGL162W Zn(II)2Cys6 family transcription factor genetic 1 1 1 Dosage Rescue
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking genetic 1 1 1 Dosage Rescue
HUL4 YJR036C Protein with similarity to hect domain E3 ubiquitin-protein ligases genetic 1 1 1 Dosage Rescue
VPS25 YJR102C Component of the ESCRT-II complex genetic 1 1 1 Dosage Rescue
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase genetic 1 1 1 Dosage Rescue
THI7 YLR237W Plasma membrane transporter responsible for the uptake of thiamine genetic 1 1 1 Dosage Rescue
YNL095C YNL095C Putative protein of unknown function genetic 1 1 1 Dosage Rescue
MGE1 YOR232W Mitochondrial matrix cochaperone genetic 1 1 1 Dosage Rescue
FMP30 YPL103C Protein with a role in maintaining mitochondrial morphology genetic 1 1 1 Dosage Rescue
PIS1 YPR113W Phosphatidylinositol synthase genetic 1 1 1 Dosage Rescue
CDC11 YJR076C Component of the septin ring that is required for cytokinesis physical 1 1 1 Affinity Capture-Western
BNI1 YNL271C Formin genetic 1 1 1 Phenotypic Suppression
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Synthetic Growth Defect
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Dosage Lethality
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Dosage Lethality
BDF2 YDL070W Protein involved in transcription initiation physical 1 1 1 Biochemical Activity
ADA2 YDR448W Transcription coactivator genetic 1 1 1 Synthetic Growth Defect
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Negative Genetic
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome genetic 1 1 1 Dosage Lethality
BSP1 YPR171W Adapter that links synaptojanins to the cortical actin cytoskeleton physical 1 1 1 Biochemical Activity
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Synthetic Growth Defect
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
CCT7 YJL111W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Dosage Lethality
CAM1 YPL048W One of two isoforms of the gamma subunit of eEF1B physical 1 1 1 Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 PCA
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Positive Genetic
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 1 1 1 Biochemical Activity
BNA3 YJL060W Kynurenine aminotransferase physical 1 1 1 Biochemical Activity
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
ARF1 YDL192W ADP-ribosylation factor genetic 1 1 1 Dosage Lethality
BUB2 YMR055C Mitotic exit network regulator genetic 1 1 1 Phenotypic Enhancement
BUD13 YGL174W Subunit of the RES complex genetic 1 1 1 Negative Genetic
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 1 1 1 Synthetic Growth Defect
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p physical 1 1 1 Biochemical Activity
CAF120 YNL278W Part of the CCR4-NOT transcriptional regulatory complex physical 1 1 1 Biochemical Activity
ADK1 YDR226W Adenylate kinase, required for purine metabolism genetic 1 1 1 Negative Genetic
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network physical 1 1 1 PCA
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network genetic 1 1 1 Dosage Lethality
ACS2 YLR153C Acetyl-coA synthetase isoform physical 1 1 1 Affinity Capture-MS
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) physical 1 1 1 Biochemical Activity
AFR1 YDR085C Protein required for pheromone-induced projection (shmoo) formation genetic 1 1 1 Dosage Lethality
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Biochemical Activity
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 1 1 1 Proximity Label-MS
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Negative Genetic
AIP5 YFR016C Protein that positively regulates actin assembly genetic 1 1 1 Dosage Rescue
BOP2 YLR267W Protein of unknown function genetic 1 1 1 Dosage Lethality
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway physical 1 1 1 Biochemical Activity
ATG20 YDL113C Sorting nexin family member physical 1 1 1 Biochemical Activity
ATG20 YDL113C Sorting nexin family member genetic 1 1 1 Dosage Lethality
AIR1 YIL079C Zinc knuckle protein genetic 1 1 1 Dosage Lethality
ARG1 YOL058W Arginosuccinate synthetase physical 1 1 1 Biochemical Activity
APL4 YPR029C Gamma-adaptin genetic 1 1 1 Dosage Lethality
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Negative Genetic
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex genetic 1 1 1 Dosage Lethality
ARH1 YDR376W Oxidoreductase of the mitochondrial inner membrane genetic 1 1 1 Dosage Lethality
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Negative Genetic
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 1 1 1 Dosage Lethality
ARG81 YML099C Zinc finger transcription factor involved in arginine-responsive genes genetic 1 1 1 Dosage Lethality
BIT61 YJL058C Subunit of TORC2 membrane-associated complex genetic 1 1 1 Dosage Lethality
ATG39 YLR312C Transmembrane receptor with a role in nucleophagy genetic 1 1 1 Dosage Lethality
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
ALY2 YJL084C Alpha arrestin, Ub-ligase adaptor for Rsp5p physical 1 1 1 Biochemical Activity
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Negative Genetic
ACF4 YJR083C Protein of unknown function physical 1 1 1 Biochemical Activity
ADY3 YDL239C Protein required for spore wall formation physical 1 1 1 Biochemical Activity
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Dosage Lethality
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 1 1 1 Biochemical Activity
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Negative Genetic
BRF1 YGR246C TFIIIB B-related factor genetic 1 1 1 Dosage Lethality
BDP1 YNL039W Essential subunit of RNA polymerase III transcription factor (TFIIIB) genetic 1 1 1 Negative Genetic
AMA1 YGR225W Activator of meiotic anaphase promoting complex (APC/C) genetic 1 1 1 Phenotypic Suppression
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase physical 1 1 1 Biochemical Activity
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Synthetic Growth Defect
BUD4 YJR092W Anillin-like protein involved in bud-site selection genetic 1 1 1 Dosage Lethality
ATS1 YAL020C Protein required for modification of wobble nucleosides in tRNA physical 1 1 1 Biochemical Activity
BIK1 YCL029C Microtubule-associated protein physical 1 1 1 Biochemical Activity
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation genetic 1 1 1 Positive Genetic
BBP1 YPL255W Protein required for the spindle pole body (SPB) duplication physical 1 1 1 Biochemical Activity
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p genetic 1 1 1 Dosage Lethality
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
ARG82 YDR173C Inositol polyphosphate multikinase (IPMK) genetic 1 1 1 Dosage Lethality
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 1 1 1 Negative Genetic
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
CDC19 YAL038W Pyruvate kinase genetic 1 1 1 Negative Genetic
ADY4 YLR227C Structural component of the meiotic outer plaque genetic 1 1 1 Dosage Lethality
CCH1 YGR217W Voltage-gated high-affinity calcium channel physical 1 1 1 Affinity Capture-MS
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Dosage Lethality
AUA1 YFL010W-A Protein required for the negative regulation by ammonia of Gap1p genetic 1 1 1 Negative Genetic
ADE1 YAR015W N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase genetic 1 1 1 Synthetic Growth Defect
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
BCH2 YKR027W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Dosage Lethality
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein physical 1 1 1 Biochemical Activity
BPH1 YCR032W Protein homologous to Chediak-Higashi syndrome and Beige proteins genetic 1 1 1 Dosage Lethality
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy genetic 1 1 1 Negative Genetic
BYE1 YKL005C Negative regulator of transcription elongation genetic 1 1 1 Dosage Lethality
AHC2 YCR082W Component of the ADA histone acetyltransferase complex genetic 1 1 1 Dosage Lethality
ALR2 YFL050C Probable Mg(2+) transporter genetic 1 1 1 Dosage Lethality
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation genetic 1 1 1 Dosage Lethality
CDA1 YLR307W Chitin deacetylase physical 1 1 1 Biochemical Activity
AIM29 YKR074W Protein of unknown function genetic 1 1 1 Negative Genetic
CCW22 YDR134C Cell wall protein physical 1 1 1 Biochemical Activity
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Negative Genetic
BNA2 YJR078W Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase physical 1 1 1 Affinity Capture-MS
ALO1 YML086C D-Arabinono-1,4-lactone oxidase genetic 1 1 1 Dosage Lethality
ASI2 YNL159C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
BAP2 YBR068C High-affinity leucine permease genetic 1 1 1 Dosage Lethality
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Dosage Lethality
BIG1 YHR101C Integral membrane protein of the endoplasmic reticulum genetic 1 1 1 Negative Genetic
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Negative Genetic
ATG41 YPL250C Protein of unknown function physical 1 1 1 Biochemical Activity
ATG41 YPL250C Protein of unknown function genetic 1 1 1 Dosage Lethality
BSC4 YNL269W Protein of unknown function genetic 1 1 1 Negative Genetic
AGC1 YPR021C Mitochondrial amino acid transporter genetic 1 1 1 Dosage Lethality
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic